<PAGE> PAGE 1
000 A000000 02/28/95
000 C000000 760110
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 3.0
000 J000000 U
001 A000000 MEDICAL RESEARCH INVESTMENT FUND, INC.
001 B000000 811-4196
001 C000000 7132609053
002 A000000 5847 SAN FELIPE, SUITE 4100
002 B000000 HOUSTON
002 C000000 TX
002 D010000 77057
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
062 A000000 N
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 0.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
071 A000000 1668
071 B000000 2502
071 C000000 12980
071 D000000 13
072 A000000 6
074 N000000 13228
074 T000000 13178
075 A000000 0
075 B000000 13031
077 A000000 N
<PAGE> PAGE 2
SIGNATURE DAN E WATSON
TITLE PRESIDENT
