MEDICAL RESEARCH INVESTMENT FUND INC
PRE 14A, 1996-07-23
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                            SCHEDULE 14A INFORMATION


           Proxy Statement Pursuant to Section 14(a) of the Securities
                      Exchange Act of 1934 (Amendment No. )


Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check
the  appropriate  box: [X]  Preliminary  Proxy  Statement [ ]  Definitive  Proxy
Statement [ ] Definitive  Additional  Materials [ ] Soliciting Material Pursuant
to Rule 14a-11(c) or Rule 14a-12

                     Medical Research Investment Fund, Inc.
                (Name of Registrant as Specified in Its Charter)

                                Allison B. Crane
   (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of filing fee (Check the appropriate box):
[X] $125 per Exchange Act Rules  0-11(c)(1)(ii),  14a-6(i)(1),  14a-6(j)(2)  [ ]
$500  per  each  party  to  the  controversy   pursuant  to  Exchange  Act  Rule
14a-6(i)(3).  [ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(4)
and 0-11.

1) Title of each class of securities to which transaction applies:

2) Aggregate number of securities to which transactions applies:

3) Per united price or other underlying value of transaction computed pursuant
   to Exchange Act Rule 0-11: (1)

4) Proposed maximum aggregate value of transactions:

[ ] Check box if any part of the fee is offset as provided by Exchange  Act Rule
0-11(a)(2)  and  identify  the  filing  for  which the  offsetting  fee was paid
previously.  Identify the previous filing by registration  statement  number, or
the Form or Schedule and the date of its filing.

1) Amount Previously Paid:

2) Form, Schedule or Registration Statement No.:

3) Filing Party:

4) Date Filed:

(1) Set forth the amount on which the filing fee is calculated and state how it
    was determined
<PAGE>
                                                          Preliminary Copy

                  MEDICAL RESEARCH INVESTMENT FUND, INC.

                                                              August 2, 1996

Dear Stockholders:

         On August 29, 1996, a Special  Meeting of the  Stockholders  of Medical
Research  Investment  Fund,  Inc.  (the  "Fund") will be held to vote on several
important  proposals.  Adoption of these  proposals,  which the Fund's  Board of
Directors has approved and believe will provide significant benefits to the Fund
and its stockholders requires stockholder  approval.  As a stockholder,  you are
entitled to cast one vote for each share that you own.

Voting Only Takes a Few Minutes - Please Respond Promptly.

         Your vote is  important,  no matter  how many  shares  you own.  If the
required votes are not received by August 29, 1996, it will be necessary to send
further  mailings to secure it. This is a costly  process and is paid for by the
Fund.  Therefore,  you, as a  stockholder,  ultimately  pay for the expense of a
delayed  vote.  Please  sign and  return  your  proxy  promptly  to  avoid  this
unnecessary expense.

         The primary  purpose of the Meeting is to consider  proposals  that the
Board of Directors believes will position the Fund to achieve higher returns for
stockholders by realizing certain economies of scale and operating efficiencies.
The  anticipated  effect  of  these  proposals  is to  enable  the  Fund and its
stockholders to participate in a much larger  investment  portfolio with a lower
aggregate expense ratio,  broader diversity of securities  holdings and improved
stockholder  exchange  privileges.  Current shareholders will not be required to
pay any sales loads on future purchases of shares.

         In order  to  achieve  these  benefits,  the  Board  of  Directors  has
appointed Eaton Vance Management as administrator and Eaton Vance  Distributors,
Inc. as distributor of the Fund. No change is occurring in the investment  focus
of the Fund, the investment adviser, or the underlying  portfolio of medical and
health sciences equity securities. G/A Capital Management, Inc. will continue as
the investment  adviser,  and I will remain as the portfolio  manager.  However,
certain changes in the legal structure of the Fund require stockholder approval.

         Eaton Vance, founded in 1924, advises, administers and distributes more
than 150 mutual funds investing in more than 60 different investment portfolios.
Total assets under management exceed $16 billion. The proposals to be considered
at this  Meeting  will have the effect of adding the Fund to the 56 mutual funds
that comprise the Eaton Vance Traditional family of funds.




<PAGE>



Other Proposals You are Voting On.

         At the  Meeting,  stockholders  will  elect  Directors  and be asked to
approve auditors. Stockholders also will be asked to amend the Fund's investment
objectives and basic investment  policies to clarify the management focus of the
Fund.  Finally,  stockholders  will also be asked to amend  certain  fundamental
investment  restrictions  to modernize  them  consistent  with current  industry
standards.


             THIS IS A VERY IMPORTANT MEETING.  IF YOU DO NOT PLAN
             TO ATTEND IN PERSON, PLEASE SIGN, DATE AND RETURN THE
                            ENCLOSED PROXY CARD TODAY.

         The matters to be presented  to the Meeting are  described in detail in
the enclosed proxy  statement.  The Board of Directors  believes that all of the
proposals are in the best interests of the Fund and its stockholders.  The Board
of Directors believes that  restructuring the Fund will not expose  stockholders
to significant  new risks and will enable them to participate in a larger,  more
diversified and potentially more attractive  investment portfolio and to achieve
cost savings over time.
                           For the Board of Directors



                           Samuel D. Isaly, President and Director


==============================================================================
YOUR BOARD OF DIRECTORS URGES YOU TO VOTE IN FAVOR OF ALL
PROPOSALS, AND LOOKS FORWARD TO RECEIVING YOUR PROXY SO YOUR
SHARES CAN BE VOTED AT THE MEETING.  FOR YOUR CONVENIENCE AND TO
SPEED DELIVERY OF YOUR PROXY, PLEASE USE THE ENCLOSED POSTAGE-PAID
ENVELOPE. YOUR PROMPT RESPONSE IS APPRECIATED.  THANK YOU.
==============================================================================



<PAGE>



                                      MEDICAL RESEARCH INVESTMENT FUND, INC.
                                 5847 SAN FELIPE, SUITE 4100, HOUSTON, TX 77057

                                     Notice of Special Meeting of Stockholders
                                            To Be Held August 29, 1996

         A Special Meeting of Stockholders of Medical Research  Investment Fund,
Inc.  (the  "Fund"),  will be held at the offices of  Shearman &  Sterling,  599
Lexington Avenue, New York, New York on August 29, 1996, commencing at 2:00 P.M.
(Eastern time), for the following purposes:

         1.       To consider and act upon a proposal to adopt a new  investment
                  policy to authorize the Fund to invest its  investable  assets
                  in a specific  corresponding  open-end  management  investment
                  company  (the  "Portfolio")  having   substantially  the  same
                  investment  objective,  policies and restrictions as the Fund,
                  and to  supplement  investment  restrictions  to  permit  such
                  investment.

         2.       To consider and act upon a proposal to  authorize  the Fund to
                  vote at a meeting of holders of interests in the  Portfolio to
                  (A)  elect a  board  of  trustees  of the  Portfolio;  and (B)
                  approve the  Investment  Advisory  Agreement  (as set forth in
                  Exhibit A to the  accompanying  Proxy  Statement)  between the
                  Portfolio and its investment adviser,  G/A Capital Management,
                  Inc.

     3.           To fix the number of  Directors at six, and to elect a Board 
                  of Directors until their successors are elected and 
                  qualified.

         4.       To ratify or reject the  selection of Tait,  Weller & Baker as
                  the independent certified public accountants to be employed by
                  the Fund to sign or certify financial  statements which may be
                  filed by the Fund with the Securities and Exchange  Commission
                  in respect of all or any part of its current fiscal year.

         5.       To consider and act upon a proposal to  eliminate,  reclassify
                  and amend the Fund's investment  objectives and certain of the
                  Fund's  fundamental  investment  policies  (as  set  forth  in
                  Exhibit B to the accompanying Proxy Statement).

         6.       To  consider  and  act  upon  any  matters  incidental  to the
                  foregoing purposes or any of them, and any other matters which
                  may properly come before said meeting or any adjourned session
                  thereof.

These items are discussed in greater detail in the following pages.



                                                       1

<PAGE>



The  meeting  is  called  pursuant  to the  By-Laws  of the  Fund.  The Board of
Directors  of the Fund have fixed the close of  business on July 24, 1996 as the
record date for the  determination  of the  stockholders of the Fund entitled to
notice of and to vote at the meeting and any adjournments thereof.

                                                               SAMUEL D. ISALY
                                                                  President

August 2, 1996


IMPORTANT - Stockholders can help the Board of Directors of their Fund avoid the
necessity and additional expense to the Fund of further  solicitations to insure
a quorum by promptly  returning  the  enclosed  proxy.  The  enclosed  addressed
envelope  requires no postage if mailed in the United States and is intended for
your convenience.


                                                       2

<PAGE>



                                      MEDICAL RESEARCH INVESTMENT FUND, INC.
                                            5847 San Felipe, Suite 4100
                                                 Houston, TX 77057

                                                               August 2, 1996

                                                  PROXY STATEMENT


         A proxy is enclosed with the foregoing  Notice of a Special  Meeting of
Stockholders of Medical Research  Investment Fund, Inc. (the "Fund"), to be held
August 29, 1996 for the benefit of stockholders  who do not expect to be present
at the  meeting.  This proxy is solicited on behalf of the Board of Directors of
the Fund, and is revocable by the person giving it prior to exercise by a signed
writing filed with the  President of the Fund, or by executing and  delivering a
later dated proxy, or by attending the meeting and voting your shares in person.
Each proxy will be voted in accordance with its instructions;  if no instruction
is given,  an executed proxy will  authorize the persons named as attorneys,  or
any of them, to vote in favor of each such matter.  This proxy material is being
mailed to stockholders on or about July 30, 1996.

         The Board of Directors of the Fund has fixed the close of business July
24, 1996, as the record date for the determination of the stockholders  entitled
to  notice  of  and to  vote  at  the  meeting  and  any  adjournments  thereof.
Stockholders at the close of business on the record date will be entitled to one
vote for each share  held.  As of July 24,  1996,  there were  shares of capital
stock of the Fund  outstanding.  As of such  date,  the  following  stockholders
beneficially  owned the  following  number of shares of the Fund (at least 5% of
outstanding  shares):  . To the  knowledge of the Fund, no other person owns (of
record or beneficially) more than 5% of its outstanding shares.

         The Board of Directors of the Fund knows of no business other than that
mentioned  in Items 1  through  5 of the  Notice of the  meeting  which  will be
presented for consideration.  If any other matters are properly presented, as to
such  matters,  it is the  intention  of the persons  named as  attorneys in the
enclosed proxy to vote the proxies in accordance with their judgment.


                                PROPOSAL 1.  TO APPROVE A NEW INVESTMENT POLICY
                                   AND TO SUPPLEMENT INVESTMENT RESTRICTIONS TO
                                         PERMIT A NEW INVESTMENT STRUCTURE


         The Board of Directors of the Fund has  approved,  and is submitting to
the  stockholders  of the Fund for  approval,  the adoption of a new  investment
policy for the Fund and the addition of a  fundamental  investment  provision to
permit the Fund to invest its "investable assets"

                                                       3

<PAGE>



(portfolio   securities  and  cash)  in  a  corresponding   open-end  management
investment  company,  the Worldwide Health Sciences Portfolio (the "Portfolio"),
having substantially the same investment objective, policies and restrictions as
the Fund.  The new investment  policy and change in the investment  restrictions
for the Fund  are  subject  to  approval  by the  Fund's  stockholders.  If this
Proposal  is  approved,  the Board of  Directors  will  direct  that the  Fund's
investable assets be invested in the Portfolio,  thereby  converting the Fund to
the Hub and Spoke(R)  structure.  (Hub and Spoke(R) is a registered service mark
of Signature Financial Group, Inc.) This will permit the Fund to become a member
of the Eaton  Vance  family of funds,  as  discussed  in this  proxy  statement.
Proposals 1, 2A, 2B and 3 are  interrelated  and will only be implemented if all
are adopted.

                                               New Investment Policy

         The Board of Directors  recommends  that the  stockholders  of the Fund
approve a new  investment  policy for the Fund,  i.e., to invest its  investable
assets in the  Portfolio.  The  Portfolio  is a trust which,  like the Fund,  is
registered as an open-end management company under the Investment Company Act of
1940 (the "Act"). The Portfolio has substantially the same investment objective,
policies and  restrictions as the Fund if shareholders  approve  Proposal 5. G/A
Capital  Management,  Inc. is currently the  investment  adviser of the Fund and
will be the  investment  adviser of the  Portfolio if Proposal 2(B) is approved.
Accordingly,  by investing in the Portfolio,  the Fund would seek its investment
objective  through its investment in the  Portfolio,  rather than through direct
investments in  securities.  The Portfolio in turn would invest in securities in
accordance with its objective, policies and restrictions.

         The  Portfolio was organized as a trust under New York law on March 26,
1996.  The  interests in the Portfolio are not available for purchase by members
of the general public.

         By investing the Fund's assets in the Portfolio, the Board of Directors
expects that the Eaton Vance organization ("Eaton Vance"), discussed below, will
be in a position to sponsor  other  collective  investment  vehicles  that could
invest in the Portfolio.  Eaton Vance has employed personnel to develop such new
vehicles. Initially, another domestic and an off-shore fund will be investing in
the Portfolio on or about the date this Proposal is  implemented.  To the extent
that these  strategies are  successful,  the new Hub and Spoke  structure  could
enable the Fund to participate in a larger,  more  diversified  and  potentially
more  attractive  investment  portfolio.  The  Fund  would be in a  position  to
benefit,  directly or indirectly,  from certain economies of scale, based on the
premise that certain of the expenses of operating an  investment  portfolio  are
relatively fixed and that a larger investment portfolio may eventually achieve a
lower ratio of operating  expenses to average net assets. The Board of Directors
also  believes  that  investing  in the  Portfolio  may produce  other  benefits
resulting  from such  increased  asset  size  such as the  ability  to  purchase
securities in larger amounts than the Fund currently is able to acquire. See the
pro forma expense  tables and the  discussion  provided  below.  There can be no
assurance that these anticipated benefits will be realized.


                                                       4

<PAGE>



         To the  extent  that the Fund  invests  its  investable  assets  in the
Portfolio,  the Fund would no longer require investment  advisory services.  For
this reason,  if stockholders of the Fund approve the addition to the investment
restrictions and adopt the new investment policy described in this Proposal, and
the Fund invests its investable assets in the Portfolio, the existing investment
advisory  agreement of the Fund with the Adviser will be terminated.  Currently,
under the existing investment  advisory  agreement,  the Fund pays the Adviser a
fee computed daily and payable  monthly at an annual rate of 1.00% of the Fund's
average  daily net assets up to $30 million of such assets 0.90% of the next $20
million of such assets, and 0.75% on such assets in excess of $50 million.

         The  Portfolio  has an investment  advisory  agreement  with respect to
Portfolio  assets pursuant to which G/A will be paid a monthly fee calculated in
the same manner as the fee currently being paid by the Fund, as set forth above,
with two exceptions. First, fee reductions will occur when net assets reach $500
million pursuant to the following schedule:

                                                                      Annual
         Average Daily Net Assets                                   Asset Rate

         $500 million but less than $1 billion................         0.70%
         $1 billion but less than $1.5 billion................         0.65%
         $1.5 billion but less than $2 billion................         0.60%
         $2 billion but less than $3 billion..................         0.55%
         $3 billion and over..................................         0.50%

Second,  the foregoing fee will be subject to a performance fee  adjustment,  as
follows:

                  After 12 months,  the basic  advisory fee is subject to upward
         or downward adjustment  depending upon whether, and to what extent, the
         investment  performance  of  the  Portfolio  differs  by at  least  one
         percentage  point from the record of the Standard & Poor's Index of 500
         Common Stocks over the same period. Each percentage point difference is
         multiplied  by a  performance  adjustment  rate of 0.025%.  The maximum
         adjustment  plus/minus is 0.25%.  One twelfth (1/12) of this adjustment
         is applied each month to the average  daily net assets of the Portfolio
         over the entire performance period. This adjustment shall be based on a
         rolling  period  of up to and  including  the most  recent  36  months.
         Performance  shall be total return as computed under Rule 482 under the
         Securities Act of 1933.

The  effect  of this  performance  fee  adjustment  is that  after  one year the
advisory  fee of the  Portfolio  could be higher or lower than what the advisory
fee of the Fund would have been.

         Upon exchange of the  investable  assets of the Fund for an interest in
the  Portfolio,  the Fund will retain the  services  of Eaton  Vance  Management
("EVM"), 24 Federal Street, Boston, MA 02110 under a management agreement to act
as administrator of the Fund.  Capstone Asset Management  Company  ("Capstone"),
5847 San Felipe, Suite 4100, Houston, Texas 77507, the

                                                       5

<PAGE>



Fund's  current  administrator,   has  consented  to  this  change.  Under  this
agreement,  EVM  would  provide  the Fund with  general  office  facilities  and
supervise the overall  administration  of the Fund.  For these services EVM will
receive .25% of average  daily net assets,  which fee declines if assets grow to
over $500 million. EVM will also receive a fee at the same rate on Portfolio net
assets for  administrative  services  provided to the  Portfolio  pursuant to an
administration  agreement.  The administration  contract with the Fund's current
administrator,  Capstone, will be terminated. Such contract has a fee of .25% of
average daily net assets which does not decline with asset growth.  In addition,
Capstone  receives  $2,000 per month for  bookkeeping  services  for which Eaton
Vance would not be separately compensated.

         EVM is a  Massachusetts  business  trust  and part of the  Eaton  Vance
organization.  Eaton Vance,  its affiliates and its  predecessor  companies have
been managing  assets of individuals and  institutions  since 1924, and managing
investment  companies  since  1931.  Eaton Vance acts as  investment  adviser to
investment  companies  and various  individual  and  institutional  clients with
assets under  management of over $16 billion.  EVM provides  administrative  and
management  services  to all of the Eaton  Vance  funds,  as well as The  Wright
Managed  Income Trust,  The Wright  Managed  Equity Trust,  The Wright  EquiFund
Equity Trust and The Wright Managed Blue Chip Series Trust.  The Wright group of
funds has assets of over $1 billion. Eaton Vance is a wholly-owned subsidiary of
Eaton Vance Corp.  ("EVC"),  a publicly held holding company,  which through its
subsidiaries  and  affiliates,  is primarily  engaged in investment  management,
administration,  and marketing activities.  Eaton Vance has utilized the Hub and
Spoke structure since 1992 and currently sponsors over 60 Hub funds and over 150
Spoke funds. The Fund, therefore, would become part of the Eaton Vance family of
funds with an exchange privilege for existing fund shareholders that includes 56
different mutual funds. See "Expanded Exchange Privilege Below".

         The Board of Directors  has also approved the  replacement  of Capstone
Asset  Planning  Company  with  Eaton  Vance   Distributors,   Inc.  ("EVD")  as
distributor of the Fund.  Capstone has consented to this change.  EVD intends to
sponsor both domestic and off-shore  investment  companies  which will invest in
the Portfolio in the fall of 1996. EVD, which has over 100 full-time  employees,
acts as  Principal  Underwriter  for over 150  investment  companies  (or series
thereof),  each of which  makes a  continuous  offering  of  shares.  EVD has an
international  distribution network and substantial financial resources. EVD has
dealer  agreements  with over 1,800 U.S.  registered  broker-dealers,  banks and
other financial intermediaries.

         EVD also acts as the Placement  Agent for the Portfolio.  The Placement
Agent  Agreement  is  renewable  annually by the  Portfolio's  Board of trustees
(including a majority of the independent  trustees),  may be terminated on sixty
days' notice either by such trustees or by vote of a majority of the outstanding
voting  securities  of the  Portfolio or on six months'  notice by the Placement
Agent and is automatically terminated upon assignment.

         The  Portfolio  and  the  Fund,  as the  case  may  be,  will  each  be
responsible  for all  respective  costs and expenses not expressly  stated to be
payable  by the  Adviser  under  the  investment  advisory  agreement  with  the
Portfolio, by EVM under its administration agreement

                                                       6

<PAGE>



with the Portfolio, or by EVM under its management agreement with the Fund. Such
costs and expenses to be borne by the  Portfolio  and the Fund,  as the case may
be, include, without limitation:  custody and transfer agency fees and expenses,
including those incurred for determining net asset value and keeping  accounting
books and records; expenses of pricing and valuation services; the cost of share
certificates;  membership dues in investment company organizations;  expenses of
acquiring,  holding and disposing of securities and other investments;  fees and
expenses of registering  under the securities  laws and the  governmental  fees;
expenses of reporting to stockholders and investors;  proxy statements and other
expenses of stockholders' or investors' meetings;  insurance premiums;  printing
and mailing expenses;  interest,  taxes and corporate fees; legal and accounting
expenses;  compensation  and expenses of trustees or Directors,  as the case may
be, not affiliated with EVM or G/A; and investment  advisory fees. The Portfolio
and the Fund will also each bear expenses incurred in connection with litigation
in which the Portfolio or the Fund, as the case may be, is a party and any legal
obligation to indemnify its  respective  officers and trustees or Directors,  as
the case may be, with respect thereto.

         The following  table shows the actual  expenses of the Fund for the six
months ended February 29, 1996, and a pro forma adjustment  thereof assuming the
Fund had invested its  investable  assets in the Portfolio for the entire period
then ended.  The pro forma  adjustment  does not include the estimated  costs of
this proxy solicitation  because Eaton Vance will bear such costs, but assumes a
waiver of Fund  management  fees of .15% of average  daily net  assets.  The pro
forma  adjustment  assumes  that:  (i) there were no holders of interests in the
Portfolio other than the Fund; and (ii) the average daily net assets of the Fund
and the Portfolio  were equal to the actual average daily net assets of the Fund
during the period.




              FUND OPERATING EXPENSES FOR THE SIX MONTHS
                        ENDED FEBRUARY 29, 1996
            (annualized as a percent of average daily net assets)

                                              Pro Forma (assuming that
                                                    the average
                                              daily net assets invested
                                                    by the Fund
                                                 in the Portfolio were
                                                     $29,060,000     )

                                    Actual            Fund   Portfolio Total
Annual Fund Operating Expenses
         Investment advisory (and
           administration) fees     1.23%             0.10%    1.23%   1.33%
         Rule 12b-1 Fees            0.25%             0.25%    0.00%   0.25%
         Other expenses
                                    0.53%             0.27%    0.15%   0.42%
                                    -----             -----    -----   -----
Total Fund Operating Expenses       2.01%             0.62%    1.38%   2.00%
                                     ----             -----    -----   -----



        Assuming  that  the  Fund was the only  holder  of an  interest  in the
Portfolio and that the Fund was fully invested therein,  the net asset value per
share, distributions per share and net

                                                       7

<PAGE>



investment  income per share of the Fund would have been about the same on a pro
forma  basis as the actual net asset  value,  distributions  and net  investment
income per share of the Fund  during the period  indicated.  If the  Portfolio's
assets grew so that average  daily net assets were $150  million,  the projected
total operating expense ratio would be reduced to 1.88%.

         Eaton  Vance also has agreed to  maintain  the  expenses of the Fund to
ensure they do not exceed 2.0% of average  daily net assets  through  August 31,
1999.  Currently,  Capstone and G/A have agreed to maintain expenses at 2.50% of
average daily net assets. Through August 31, 1995, the Fund historically has had
an annual expense ratio of no lower than 2.44% since inception.

         In recommending  that the stockholders  authorize the conversion of the
Fund to the Hub and Spoke  structure,  the  Board of  Directors  has taken  into
account  and  evaluated  the  possible  effects  which  increased  assets in the
Portfolio  may have on the expense  ratio of the Fund.  There is, of course,  no
assurance  that the net  assets of the  Portfolio  will  grow.  After  carefully
weighing the costs involved  against the anticipated  benefits of converting the
Fund to the Hub and Spoke structure,  the Board of Directors recommends that the
stockholders of the Fund vote to approve Proposal 1.

     If Proposal 1 is approved,  the Board of Directors expects to implement the
investment  policy for the Fund by causing the Fund to exchange  its  investable
assets  (portfolio  securities  and  cash)  as  well  as  certain  other  assets
(including  receivables  for securities  sold from the portfolio and receivables
for  interest on portfolio  securities)  for an interest in the  Portfolio.  The
proposed transaction will not alter the rights and privileges of stockholders of
the Fund. The value of a  stockholder's  investment in the Fund will be the same
immediately after the Fund's  investment in the Portfolio as immediately  before
that investment.  Of course, the value of a stockholder's investment in the Fund
may fluctuate thereafter.

         The Fund would be able to withdraw its  investment  in the Portfolio at
any time, if the  Directors  determine  that it is in the best  interests of the
Fund to do so. Upon any such  withdrawal,  the  Directors  would  consider  what
action might be taken,  including the investment of the investable assets of the
Fund  in  another  pooled  investment  entity  having   substantially  the  same
investment  objective as the Fund or the retention of another investment adviser
to manage the Fund's assets in  accordance  with its  investment  policies as is
presently the case.

                                           Description of the Portfolio

         The investment  objective of the Portfolio is the same as the objective
of the Fund, assuming Proposal 5 is approved. The Portfolio seeks to achieve its
investment  objective through  investments limited to the types of securities in
which the Fund is authorized to invest. The investment restrictions and policies
of the  Portfolio  are such that the Portfolio may not invest in any security or
engage  in any  transaction  which  would  not be  permitted  by the  investment
restrictions  and  policies  of the Fund if the Fund were to invest  directly in
such a  security  or  engage  directly  in such a  transaction,  again  assuming
Proposal 5 is approved.

                                                       8

<PAGE>




         If the proposed investment in the Portfolio is implemented,  the Fund's
assets  would no longer be directly  invested in a portfolio of  securities  but
would  rather be  invested  in the  securities  of a single  issuer,  i.e.,  the
Portfolio,  which  is a New  York  trust,  and  is  registered  as  an  open-end
management  investment  company  under the Act.  Nevertheless,  inasmuch  as the
assets of the Portfolio would be directly invested in a portfolio of securities,
the Fund believes there are no material risks of investing in the Portfolio that
are  different  from  those to  which  stockholders  of the  Fund are  currently
subject.

         The approval of the Portfolio's  investors (i.e.,  holders of interests
in the  Portfolio,  such as the Fund) would be required to change certain of its
investment  restrictions;  however,  any  change  in  nonfundamental  investment
policies  would  not  require  such  approval.  For a  discussion  of when  Fund
stockholders would be requested to vote on Portfolio matters, see page below.

         Like the Fund,  the  Portfolio  determines  its net asset value once on
each day the New York Stock Exchange (the "Exchange") is open for trading, as of
the close of regular trading on the Exchange. The Portfolio's net asset value is
computed  by  determining  the  value  of  the  Portfolio's  total  assets  (the
securities it holds plus any cash or other assets,  including  interest  accrued
but  not yet  received),  and  subtracting  all of the  Portfolio's  liabilities
(including  accrued  expenses).  The Portfolio will value its assets in the same
manner as the Fund.

          To the extent sales prices are available,  securities  that are traded
on a recognized stock exchange,  whether U.S. or foreign, are valued at the last
sale price on that exchange prior to the time when assets are valued or prior to
the close of trading on the New York Stock Exchange. In the event that there are
no sales, the last available sale price will be used. If a security is traded on
more than one  exchange,  the latest  price on the  exchange  where the stock is
primarily  traded will be used.  If there is no sale that day or if the security
is  not  listed,  the  security  is  valued  at its  last  sale  quotation.  The
calculation   of  the   Portfolio's   net  asset   value  may  not  take   place
contemporaneously  with the times  noted  above for  determining  the  prices of
certain portfolio securities, including foreign securities. If events materially
effecting the value of such securities  occur between the time when their prices
are determined and the time the Portfolio's net asset value is calculated,  such
securities  will be  valued at fair  value as  determined  in good  faith by the
Trustees.  Also, for any security for which application of the preceding methods
of  valuation  results  in a  price  for a  security  that is  deemed  not to be
representative of the market value of such security, the security will be valued
at fair value under the supervision and responsibility of the Board of Trustees.

         Futures contracts and call options written on portfolio securities will
be priced at the latest  sales  price on the  principal  exchange  on which such
options are normally  traded or, if there have been no sales on such exchange on
that day, at the closing asked price.  Short-term  investments having a maturity
of 60 days or less are valued on the basis of amortized  cost.  All other assets
and  securities  held by the Portfolio  (including  restricted  securities)  are
valued at fair value as  determined  in good  faith  under the  supervision  and
responsibility  of the Board of Trustees.  Any assets that are  denominated in a
foreign  currency are translated into U.S.  dollars of the last quoted spot rate
of exchange prevailing on each valuation date.

                                                       9

<PAGE>




         The Fund's net asset  value is  determined  at the same time and on the
same days that the net asset value of the  Portfolio  is  calculated.  Net asset
value per share is computed by  determining  the value of the Fund's assets (its
investment  in the Portfolio and other  assets),  subtracting  all of the Fund's
liabilities  (including accrued expenses),  and dividing the result by the total
number of shares outstanding at such time.

         Interests in the Portfolio have no  pre-emptive  or conversion  rights,
and are fully paid and non-assessable,  except as set forth below. The Portfolio
normally will not hold meetings of holders of such interests  except as required
under the Act. The  Portfolio  would be required to hold a meeting of holders in
the event that at any time less than a majority of the trustees  holding  office
had been  elected by holders.  The  trustees of the  Portfolio  continue to hold
office until their successors are elected and have qualified.  Holders holding a
specified  percentage interest in the Portfolio may call a meeting of holders in
the  Portfolio  for the  purpose  of  removing  any  trustee.  A trustee  of the
Portfolio  may be  removed  upon a majority  vote of  holders  in the  Portfolio
qualified to vote in the election.  The Act requires the Portfolio to assist its
holders in calling such a meeting. Upon liquidation of the Portfolio, holders in
the  Portfolio  would be  entitled  to share  pro rata in the net  assets of the
Portfolio available for distribution to holders.

         Each holder in the  Portfolio is entitled to vote in  proportion to its
share of the interests in the Portfolio. Except as described below, whenever the
Fund is requested to vote on matters pertaining to the Portfolio,  the Fund will
hold a meeting of its  stockholders and will cast its votes  proportionately  as
instructed by Fund stockholders.

         Subject to applicable statutory and regulatory  requirements,  the Fund
would not request a vote of its  stockholders  with  respect to (a) any proposal
relating to the  Portfolio,  which  proposal,  if made with respect to the Fund,
would not require the vote of the stockholders of the Fund, or (b) any proposal,
with respect to the Portfolio that is identical,  in all material respects, to a
proposal that has  previously  been approved by  stockholders  of the Fund.  Any
proposal  submitted to holders in the Portfolio,  and that is not required to be
voted on by  stockholders  of the  Fund,  would  nonetheless  be voted on by the
Directors of the Fund.

         Investments in the Portfolio may not be  transferred,  but a holder may
withdraw  all or any portion of its  investment  at any time at net asset value.
Each  holder  in the  Portfolio,  including  the Fund,  will be  liable  for all
obligations  of the  Portfolio.  However,  the risk of a holder in the Portfolio
incurring   financial   loss  on  account  of  such   liability  is  limited  to
circumstances  in which both  inadequate  insurance  exists,  and the  Portfolio
itself is unable to meet its obligations.  Thus, stockholders of the Fund should
not experience losses from the new investment structure itself.

         The  Portfolio  has its own board of trustees,  including a majority of
trustees  who are not  "interested"  persons of the  Portfolio as defined in the
Act.  The present  trustees  of the  Portfolio  are  identical  to the  proposed
Directors of the Fund and are listed in Proposal 2A of this Proxy Statement.


                                                       10

<PAGE>



                                   Tax Considerations

         The  Internal  Revenue  Service has issued  private  letter  rulings to
numerous investment companies, including EVM sponsored funds, to the effect that
this type of transaction  will not result in recognition of capital gains.  Such
rulings are not binding on the Service with  respect to the Fund.  Nevertheless,
the Fund has  received an opinion of tax  counsel,  Brown & Wood,  to the effect
that,   although  there  is  no  judicial   authority  directly  on  point,  the
contribution  of its assets to the  Portfolio in exchange for an interest in the
Portfolio  will not  result in the  recognition  of gain or loss to the Fund for
federal  income tax purposes  pursuant to Internal  Revenue Code Section 721 and
related  authorities.  The Fund has not applied  for a ruling from the  Internal
Revenue  Service to the same  effect and legal  opinions  are not binding on the
Service. If it were determined that the transaction was taxable,  the Fund would
realize and recognize gain in an amount equal to the appreciation  (undiminished
by losses) in the transferred assets as of the date of the transfer (the "deemed
gain"). If the Fund did not make a distribution to its stockholders equal to all
or a portion of the deemed gain, the Fund could be subject to tax (plus interest
and  penalties)  on all or a portion of the deemed gain.  Alternatively,  if the
Fund were to make a distribution  to its  stockholders in an amount equal to all
or a portion  of the  deemed  gain,  then its  stockholders  at the time of such
distribution  would be taxed on the  amount  distributed  and the Fund  could be
required to pay penalties and/or interest. Depending on the amount and nature of
the deemed gain and the Fund's previous  distributions  of gains with respect to
the same  taxable  year,  the Fund might be  required  to make the  distribution
described in the preceding sentence in order to preserve its qualification under
the Internal Revenue Code (the "Code") as a regulated investment company.

         As of February  29,  1996,  the gross  unrealized  appreciation  in the
assets of the Fund on a Federal Income tax basis was  $8,011,579.  The amount of
gross unrealized  appreciation in the assets of the Fund at the time of transfer
of the  Fund's  assets  to the  Portfolio  may be more or less  than the  amount
indicated in the  preceding  sentence,  and no assurance  can be given as to the
magnitude of such amount at the time of such transfer.

         As a regulated investment company under the Code, the Fund does not pay
federal income or excise taxes to the extent that it distributes to stockholders
its net investment  income and net realized capital gains in accordance with the
timing  requirements  imposed by the Code. As a  partnership  under the Internal
Revenue  Code,  the  Portfolio  does not pay  federal  income or  excise  taxes.
Provided the Fund qualifies as a regulated investment company for federal income
tax  purposes  and the  Portfolio  is treated as a  partnership  for federal tax
purposes,  neither is liable for state income, corporate excise tax or franchise
tax.

                   Proposed Supplement to Investment Restrictions

     Certain of the Fund's investment  restrictions must be amended,  eliminated
or  reclassified  in order for the Fund to invest its  investable  assets in the
Portfolio.  (See investment  restrictions  (1), (4), (8), (11), (12), (14), (15)
and (17) in Exhibit B.) The Board of Directors of the Fund

                                                       11

<PAGE>



has approved,  subject to a  stockholder  vote, a  supplemental  provision to be
added to the  investment  restrictions  of the Fund to permit  it to invest  its
investable assets in the Portfolio.

         The Board of Directors  proposes that these  restrictions and all other
investment   restrictions  be  supplemented   with  an  additional   fundamental
investment provision as follows:  "(18)  Notwithstanding the investment policies
and  restrictions  of the Fund,  the Fund may invest  its assets in an  open-end
management  investment company with substantially the same investment objective,
policies and restrictions as the Fund."

         The additional investment provision would also apply to any conflicting
nonfundamental  investment policies.  (The current investment restrictions would
also be revised if Proposal 5 is approved.)

                          Expanded Exchange Privilege

         Because  the Fund would  become a member of the Eaton  Vance  family of
funds if this Proposal is approved,  Fund  shareholders  would be able to freely
exchange  into the following  mutual funds without  payment of a sales charge or
fund exchange fee:



                                                       12

<PAGE>



                         ELIGIBLE EXCHANGE PRIVILEGE FUNDS


                                                 Equity Funds

EV Traditional  Asian Small Companies Fund EV Traditional  Emerging Markets Fund
EV Traditional Information Age Fund EV Traditional Investors Fund EV Traditional
Greater  China  Growth Fund EV  Traditional  Greater  India Fund EV  Traditional
Growth Fund EV Traditional  Special  Equities Fund EV Traditional  Stock Fund EV
Traditional Tax-Managed Growth Fund EV Traditional Total Return Fund

                                                Income Funds

Eaton Vance Income Fund of Boston
EV Traditional Government Obligations Fund

                                                Money Market Funds

Eaton Vance Cash Management Fund
Eaton Vance Tax Free Reserves

                                               Municipal Bond Funds

Eaton Vance Municipal Bond Fund L.P. EV Traditional  Alabama  Municipals Fund EV
Traditional  Arizona Municipals Fund EV Traditional  Arkansas Municipals Fund EV
Traditional  California  Municipals Fund EV Traditional Colorado Municipals Fund
EV Traditional  Connecticut  Municipals Fund EV Traditional  California  Limited
Maturity
  Municipals Fund
EV Traditional Connecticut Limited Maturity
  Municipals Fund
EV Traditional Florida Insured Municipals
  Fund
EV Traditional Florida Limited Maturity
  Municipals Fund

                                         Municipal Bond Funds (Continued)

EV Traditional Florida Municipals Fund EV Traditional Georgia Municipals Fund EV
Traditional  Hawaii Municipals Fund EV Traditional High Yield Municipals Fund EV
Traditional  Kansas Municipals Fund EV Traditional  Kentucky  Municipals Fund EV
Traditional Louisiana Municipals Fund EV Traditional Maryland Municipals Fund EV
Traditional  Massachusetts  Municipals  Fund  EV  Traditional  Michigan  Limited
Maturity
  Municipals Fund
EV Traditional Michigan Municipals Fund
EV Traditional Minnesota Municipals Fund
EV Traditional Mississippi Municipals Fund
EV Traditional Missouri Municipals Fund
EV Traditional National Limited Maturity
  Municipals Fund
EV Traditional National Municipals Fund
EV Traditional New Jersey Limited Maturity
  Municipals Fund
EV Traditional New Jersey Municipals Fund
EV Traditional New York Limited Maturity
  Municipals Fund
EV Traditional New York Municipals Fund
EV Traditional North Carolina Municipals
  Fund
EV Traditional Ohio Limited Maturity
  Municipals Fund
EV Traditional Ohio Municipals Fund
EV Traditional Oregon Municipals Fund
EV Traditional Pennsylvania Municipals Fund
EV Traditional South Carolina Municipals
  Fund
EV Traditional Tennessee Municipals Fund
EV Traditional Texas Municipals Fund
EV Traditional Virginia Municipals Fund
EV Traditional West Virginia Municipals Fund

The Fund can change this exchange privilege upon 60 days notice to shareholders.
The new privilege is substantially  broader than the current one provided by the
Capstone family of funds which only includes the following five funds:  Capstone
Growth  Fund,  Inc.,  Capstone  Government  Income Fund,  Capstone  Intermediate
Government Fund, Capstone Nikko Japan Fund and Capstone New Zealand Fund.

         In addition,  shareholders of record on the date of the conversion will
be  permitted to purchase  additional  shares of the Fund without a sales charge
for as long as they remain Fund shareholders.

                                        Evaluation by the Fund's Directors

         The  Board  of  Directors  of the Fund has  carefully  considered  this
Proposal  and its  potential  benefits,  which  will  in  effect  authorize  the
conversion of the Fund to the Hub and Spoke structure. In this regard, the Board
believes that the Portfolio will attract other  collective  investment  vehicles
which will have  investors  who would not  otherwise  be  investors in the Fund.
Investors in the Portfolio may include other  established  investment  companies
sponsored by Eaton Vance with  substantially the same investment  objectives and
policies  as the Fund.  By  adopting  the Hub and Spoke  structure  the Fund can
participate  in a larger,  more  diversified  and  potentially  more  attractive
investment  portfolio.  By this pooling of assets the Portfolio is likely,  over
time, to achieve a variety of operating economies.  The larger asset size of the
Portfolio,  in the  Board's  view,  can be  expected  to permit the  purchase of
investments in larger amounts than the Fund currently is able to purchase, which
may  reduce  certain   operating   expenses   indirectly  borne  by  the  Fund's
stockholders.  In  general,  to the  extent  that  certain  operating  costs are
relatively fixed and currently are borne by the Fund alone, these expenses would
instead be borne in whole or in part by the  Portfolio  and shared by the Fund's
stockholders with other investors in the Portfolio. These portfolio benefits and
economies of scale would be likely only if assets of the Portfolio  were to grow
through  investments in the Portfolio by entities in addition to the Fund. There
can be no assurance that such benefits will be realized.

         The  Board  also  considered  the  comparative  skill,  experience  and
resources  of  Eaton  Vance  and  Capstone  in  serving  as  administrator   and
distributor of the Fund especially in the proposed revised structure.  The Board
recognized  that EVM and G/A could benefit from the proposed  structure  because
such  structure  could  enable them to increase fee bearing  assets  through the
development of new vehicles to attract investor assets and that G/A and Capstone
will receive the benefits described in "Related Transactions" below.

         The  Board  of  Directors  of the  Fund  believes  that  over  time the
aggregate per share  expenses of the Fund and the Portfolio  should be less than
the  expenses  that would be incurred by the Fund if it  continued to retain the
services of an investment adviser and to invest directly in securities  although
there can be no assurance that such expense savings will be realized.  The Board
also considered risks associated with an investment in the Portfolio.  The Board
of

                                                       13

<PAGE>



Directors  believes that the Portfolio's  investment  policies and  restrictions
involve  substantially  the same risks as are associated  with the Fund's direct
investment in securities.

         The Board also considered the expanded exchange privilege which will be
available to shareholders. The number of available funds that could be exchanged
into will increase  from 5 to 56.  Although the Eaton Vance family of funds does
not have funds with identical investment objectives and policies to the Capstone
funds, the Board believes the available choices are a substantial improvement.

         Based on their  consideration,  analysis  and  evaluation  of the above
factors and other  information  deemed by them to be relevant to this  Proposal,
the  Fund's  Board  of  Directors  (including  a  majority  of  the  Independent
Directors) have concluded that it would be in the best interests of the Fund and
its  stockholders  to  approve a new  investment  policy and  supplement  to the
fundamental investment  restrictions to enable the Fund to invest its investable
assets in the Portfolio.

                                        Vote Required to Approve Proposal 1

         Approval by the  stockholders of the Fund of the new investment  policy
and  supplement  to  its  fundamental   investment   restrictions  requires  the
affirmative vote of a majority of the outstanding  voting securities of the Fund
which term as used in this Proxy  Statement  means the vote of the lesser of (a)
more than 50% of the outstanding shares of the Fund, or (b) 67% of the shares of
the  Fund  present  at the  meeting  if the  holders  of  more  than  50% of the
outstanding  shares  of the  Fund are  present  or  represented  by proxy at the
meeting.

         The Board of Directors of the Fund recommends that the  stockholders of
the Fund vote to approve  this  Proposal.  Implementation  of this  Proposal  is
dependent upon approval of Proposals 2 and 5. In the event the  stockholders  of
the Fund fail to approve this  Proposal,  the Board would continue to retain the
Adviser as the  investment  adviser  for the Fund to manage  the  Fund's  assets
through direct  investments in securities,  and the Fund's  existing  investment
advisory agreement would continue in effect in its current form.

                     PROPOSAL 2.  AUTHORIZATION TO VOTE AT MEETINGS OF
                                        PORTFOLIO INVESTORS

         Stockholders  of the Fund are being  asked to vote on  certain  matters
with  respect to the  Portfolio  because  the  Portfolio  is  expected to call a
meeting  of  its  holders   (including  the  Fund)  to  vote  on  such  matters.
Specifically,  it is expected that the Portfolio will ask its holders to vote at
such meeting to:

                  (A)  Elect a board of trustees of the Portfolio; and
                  (B) Approve the Investment  Advisory Agreement as set forth in
                  Exhibit A to this Proxy  Statement  between the  Portfolio and
                  its investment adviser, G/A Capital Management, Inc.

                                                       14

<PAGE>




         The Fund will cast its votes at the meeting of holders of  interests in
the  Portfolio  on each matter in the same  proportion  as the votes cast by the
Fund's  stockholders.  Based on the Fund's current net assets, it is anticipated
that the Fund will  hold over 99% of the  interests  in the  Portfolio  when the
conversion occurs.

                    PROPOSAL 2(A).  ELECTION OF TRUSTEES OF THE PORTFOLIO

         It is the  present  intention  that the  enclosed  proxy  will,  unless
authority to vote for election of one or more nominees is specifically  withheld
by executing the proxy in the manner stated thereon,  be used for the purpose of
authorizing  the Fund to vote in  favor of the  election  of the  following  six
nominees  indicated  below as trustees of the  Portfolio,  to hold office  until
their  successors  are  elected  and  qualified.  Please  note  that each of the
following  nominees is proposed to serve as a Director of the Fund.  The nominee
whose name is preceded by an asterisk(*)  is an "interested  person" (as defined
in the Act), by reason of his affiliation with the Eaton Vance organization.

         Name and                               Principal Occupations Over
     Other Information                            Past Five Years


Donald R. Dwight       Mr. Dwight is President of Dwight Partners, Inc. 
Age: 65; has been a    (a corporate relations and communications company) Board
trustee since          founded in 1988; Chairman of the of Newspapers of New 
June 24, 1996.         England, Inc., since 1982.  He also servesas a Director, 
                       Managing General Partner, Director General Partner, or
                       Trustee of seventy-nine investment companies advised or 
                       administered  by  EVM  or  its subsidiary,  Boston  
                       Management and Research
                       ("BMR").

*James B. Hawkes      President of the Portfolio and a Trustee since inception. 
Age 54; has been a    Executive Vice President of Eaton Vance Corp. ("EVC"), 
trustee since         EVM and (the parent of EVM), EVM and EV, Inc.(a sister 
March 26, 1996.       subsidiary of EVM) and a Director of EVC and EV, Inc. He 
                      also serves as a Director or Trustee and/or Officer of 
                      seventy-two investment companies advised or administered
                      by EVM  or BMR.

Samuel L. Hayes, III  Dr. Hayes is the Jacob H. Schiff Professor of Investment
Age: 61; has been a   Banking at Harvard Graduate School of Business 
trustee since         Administration. He also serves as a Director, Managing 
June 24, 1996.        General Partner, Director General Partner, or Trustee of 
                      eighty-two investment companies advised or administered 
                      by EVM or BMR.

Norton H. Reamer      President and a Director of United Asset Management 
Age: 60; has been a   Corporation, Director, Chairman and President of The Regis
trustee since         Fund, Inc., an open-end mutual fund.  He also serves as a 
June 24, 1996.        Director, Managing General Partner, Director General
                      Partner, or Trustee of seventy-nine investment companies.
                      advised or administered by EVM or BMR

                                                       15

<PAGE>


John L. Thorndike     Director of Fiduciary Company Incorporated in Boston,
Age 69; has been a    Massachusetts; a Trustee of the Boston Symphony Orchestra.
trustee since         He also serves as a Director, Managing General Partner,
June 24, 1996.        Director General Partner, or Trustee of seventy-nine
                      investment companies advised or administered by EVM or
                      BMR.

Jack L. Treynor       An investment adviser and consultant.  Associate Professor
Age: 66; has been a   of Finance, Loyola-Marymount University, Los Angeles,
trustee since         California (until May 1989).  Mr. Treynor is also a member
June 24, 1996.        of the Advisory Board of the Institute of Quantitive
                      Research in Finance.  He also serves as a Director,
                      Managing General Partner, Director General Partner,
                      or  Trustee of seventy-seven investment companies
                      advised or administered by EVM or BMR.

         As of July 16,  1996,  no current  or former  trustee or officer of the
Portfolio, individually or as a group, directly or indirectly beneficially owned
more than 1% of the Fund's shares then outstanding.

         It is not  expected  that any of the  nominees  referred  to above will
decline or become unavailable for election,  but in case this should happen, the
Portfolio  may vote for a substitute  nominee or nominees  (unless  authority to
vote for election of all  nominees is  specifically  withheld by  executing  the
proxy in the manner stated thereon).

         Messrs. Thorndike (Chairman),  Hayes and Reamer serve as members of the
Special Committee of the board of trustees of the Portfolio.  The purpose of the
Special Committee is to consider,  evaluate and make recommendations to the full
Board concerning (i) all contractual  arrangements with service providers to the
Portfolio,  including  advisory,  administrative,  custodial and fund accounting
services,  and  (ii)  all  other  matters  in which  Eaton  Vance,  G/A or their
affiliates have any actual or potential  conflict of interest with the Portfolio
or its interestholders.

         The  Nominating  Committee is  comprised  of four  trustees who are not
"interested  persons" as that term is defined  under the Act. The  Committee has
four-year  staggered  terms,  with one member  rotating of the  committee  to be
replaced by another  noninterested  trustee.  Messrs. Hayes (Chairman),  Reamer,
Thorndike and Treynor are currently serving on the committee. The purpose of the
Committee  is  to   recommend  to  the  Board   nominees  for  the  position  of
noninterested  trustee  and to assure  that at least a majority  of the Board of
trustees is  independent  of G/A,  Eaton Vance and their  affiliates.  The Board
will, when a vacancy exists or is anticipated,  consider any nominee for trustee
recommended by a shareholder if such recommendation is submitted to the board in
writing and contains sufficient background information concerning the individual
to enable a proper judgment to be made as to such individual's qualifications.

         Messrs.  Treynor  (Chairman)  and Dwight  serve as members of the Audit
Committee  of the board of  trustees  of the  Portfolio.  The Audit  Committee's
functions include making recommendations to the board regarding the selection of
the independent public accountants,  and reviewing with such accountants and the
Treasurer of the Portfolio matters relative to trading

                                                       16

<PAGE>



and brokerage  policies and  practices,  accounting  and auditing  practices and
procedures,  accounting records, internal accounting controls, and the functions
performed by the custodian,  transfer agent and dividend disbursing agent of the
Portfolio.

         The fees and expenses of those  trustees of the  Portfolio  who are not
members of the Eaton Vance  organization  or G/A will be paid by the  Portfolio.
For the fiscal year ended October 31, 1996,  the proposed  Directors of the Fund
will have earned the following  compensation in their  capacities as trustees of
the Portfolio and other funds in the Eaton Vance fund complex:

                         Retirement
                       Benefit Accrued                   Total
                            from                      Compensation
         Name              Complex                   Fund Complex(1)

Donald R. Dwight           $ 35,000                  $ 135,000
Samuel L. Hayes, III         33,750                    150,000
Norton H. Reamer              -0-                      135,000
John L. Thorndike             -0-                      140,000
Jack L. Treynor               -0-                      140,000


     (1) The Eaton  Vance fund  complex  consists of 211  registered  investment
companies or series thereof.

         Trustees of the Portfolio that are not affiliated  with Eaton Vance may
elect to defer receipt of all or a percentage of their annual fees in accordance
with the terms of a Deferred Compensation Plan (the "Plan").  Under the Plan, an
eligible  trustee may elect to have his deferred fees invested by a Portfolio in
the  shares of one or more  funds in the Eaton  Vance  Family of Funds,  and the
amount paid to the  trustees  under the Plan will be  determined  based upon the
performance of such  investments.  Deferral of trustees' fees in accordance with
the Plan will have a negligible effect on a Portfolio's assets, liabilities, and
net income per share, and will not obligate the Portfolio to retain the services
of any  trustee  or  obligate  the  Portfolio  to pay any  particular  level  of
compensation to the trustee.

         It  is  estimated  that  the  trustees,   as  a  group,   will  receive
approximately  $175 in compensation from the Fund and $450 from the Portfolio in
the next fiscal year of operations.  Mr. Hawkes,  a trustee of the Portfolio who
is affiliated  with EVM is  compensated by EVM and does not and will not receive
fees or renumeration directly from the Fund or the Portfolio.

         The Board of Directors of the Fund recommends that the  stockholders of
the Fund vote to  authorize  the Fund to elect each  nominee as a trustee of the
Portfolio at the meeting of the holders of interests in the Portfolio.



                                                       17

<PAGE>



                                          PROPOSAL 2(B).  APPROVAL OF THE
                                        INVESTMENT ADVISORY AGREEMENT WITH
                                           G/A CAPITAL MANAGEMENT, INC.

         G/A Capital Management, Inc. ("G/A"), the Adviser of the Fund, will act
as  investment  adviser to the  Portfolio  pursuant  to an  Investment  Advisory
Agreement between G/A and the Portfolio,  to be dated the date of the conversion
to the Hub and Spoke structure (the  "Agreement").  G/A is located at 41 Madison
Avenue,  40th Floor,  New York, New York  10010-2202.  G/A was  incorporated  in
Delaware on February 24, 1989 and is principally  owned by Samuel D. Isaly,  who
serves as the  President  of by G/A.  Assuming  Proposal 1 is  implemented,  the
Portfolio would be the only investment  company registered under the Act advised
by G/A.  Investment  decisions for the Portfolio  would be made by the portfolio
manager,  Samuel D. Isaly. Mr. Isaly has been active in international and health
care investing  throughout his career,  beginning at Chase Manhattan Bank in New
York in 1968. He studied international  economics,  mathematics and econometrics
at  Princeton  and  the  London  School  of  Economics.  His  company,  Gramercy
Associates,  was the first to develop an integrated worldwide system of analysis
on  the  100  leading  worldwide  pharmaceutical   companies,   with  investment
recommendations  conveyed  to 50 leading  financial  institutions  in the United
States and Europe beginning in 1982.  Gramercy Associates was absorbed into S.G.
Warburg & Company Inc. in 1986,  where Mr. Isaly became a Senior Vice President.
In July of 1989, Mr. Isaly joined with Mr. Viren Mehta to found the  partnership
of Mehta and Isaly.  The  operations of the combined  effort  (including G/A and
affiliated  entities)  are (1) to  provide  investment  ideas  to  institutional
investors on the subject of worldwide health care, (2) to undertake cross-border
merger and  acquisition  projects in the industry and (3) to provide  investment
management services to selected investors. G/A is registered with the Securities
and Exchange Commission as an investment adviser.

         The Board of Directors  of the Fund have  reviewed  the  Agreement  and
recommends  that the  stockholders  of the Fund  vote to  authorize  the Fund to
approve the Agreement entered into by the Portfolio at the meeting of holders of
interests  in the  Portfolio.  A copy of the  Agreement  is  attached  hereto as
Exhibit  A and the  discussion  of the  Agreement  herein  is  qualified  in its
entirety by such Agreement.

         The Agreement will remain in full force and effect through February 28,
1997, and will continue in full force and effect  indefinitely  thereafter,  but
only so long as such continuance is specifically  approved at least annually (i)
by the  board of  trustees  of the  Portfolio  or by vote of a  majority  of the
outstanding voting securities (as defined in the Act) of the Portfolio, and (ii)
by the  vote of a  majority  of  those  trustees  of the  Portfolio  who are not
interested  persons (as defined in the Act) of EVM, G/A or the Portfolio cast in
person at a meeting called for the purpose of voting on such approval.

         Under the terms of the Agreement,  the Portfolio will employ G/A to act
as investment  adviser for and to manage the investment and  reinvestment of the
assets of the Portfolio,  subject to the  supervision of its trustees.  G/A will
furnish to the Portfolio investment advice and

                                                       18

<PAGE>



assistance,  and investment advisory,  statistical and research facilities,  and
has arranged for certain members of the G/A organization to serve without salary
as officers of the Portfolio.

         In  approving  the  Agreement  for the  Portfolio,  the trustees of the
Portfolio have taken into account such factors and information as were deemed by
them  to  be  relevant  to  G/A's  investment  advisory  relationship  with  the
Portfolio. In their deliberations the trustees have considered: the requirements
and needs of the Portfolio  for advisory  services and  facilities,  the nature,
extent and quality of the advisory services and facilities  heretofore  provided
to the Fund, the ability of G/A's  personnel,  the fiduciary duties and risks to
be assumed  by the G/A  organization  and its  commitment  to  provide  advisory
services and facilities to the Portfolio on a continuing basis, the compensation
and  benefits  which will be  received by the G/A  organization  pursuant to the
Agreement,  the  necessity  that G/A  maintain its ability to retain and attract
capable  personnel to service the  Portfolio,  the  continuance  of  appropriate
incentives  to  assure  that  G/A  will  provide  high  quality  management  and
administrative  services to the  Portfolio,  the revenues,  expenses,  financial
condition,  stability and capabilities of G/A, the investment performance of the
Fund since its inception, the various investment strategies and techniques to be
employed  by G/A to enhance  the  Portfolio's  investment  performance,  current
developments  and trends in the mutual fund and  financial  services  industries
including the entry of large and highly capitalized companies which are spending
and appear to be prepared to  continue  to spend  substantial  amounts to engage
personnel  and to  provide  services  for  competing  mutual  funds,  and  other
information and factors which the trustees believed relevant to the matter.

         Pursuant  to  the  Agreement,  G/A  will  provide  the  Portfolio  with
investment research, advice and supervision,  will furnish an investment program
and  will  determine  what  securities  will be  purchased,  held or sold by the
Portfolio  and what  portion,  if any,  of the  Portfolio's  assets will be held
uninvested.  The  Agreement  requires  G/A to pay the  salaries  and fees of all
officers  of the  Portfolio  who are  members  of the G/A  organization  and all
personnel  of G/A  performing  services  relating  to  research  and  investment
activities.  The Agreement provides that the Portfolio will pay all its expenses
other than those expressly  stated to be payable by G/A, which expenses  payable
by the  Portfolio  will include,  without  implied  limitation,  (i) expenses of
maintaining the Portfolio and continuing its existence, (ii) registration of the
Portfolio under the Act, (iii)  commissions,  fees and other expenses  connected
with  the   acquisition,   holding  and  disposition  of  securities  and  other
investments,  (iv)  auditing,  accounting  and  legal  expenses,  (v)  taxes and
interest,  (vi) governmental  fees, (vii) expenses of issue, sale and redemption
of interests in the Portfolio, (viii) expenses of registering and qualifying the
Portfolio and interests in the Portfolio under federal and state securities laws
and  of  preparing  and  printing  registration  statements  or  other  offering
statements  or  memoranda  for such  purposes and for  distributing  the same to
holders and  investors,  and fees and expenses of  registering  and  maintaining
registrations  of the  Portfolio  and  of the  Portfolio's  placement  agent  as
broker-dealer or agent under state securities laws, (ix) expenses of reports and
notices to holders and of meetings of holders and proxy solicitations  therefor,
(x) expenses of reports to governmental officers and commissions, (xi) insurance
expenses,   (xii)  association   membership  dues,  (xiii)  fees,  expenses  and
disbursements of custodians and  subcustodians for all services to the Portfolio
(including without

                                                       19

<PAGE>



limitation  safekeeping of funds,  securities and other investments,  keeping of
books, accounts and records, and determination of net asset values, book capital
account  balances and tax capital account  balances),  (xiv) fees,  expenses and
disbursements of transfer agents,  dividend disbursing agents,  holder servicing
agents and  registrars  for all  services to the  Portfolio,  (xv)  expenses for
servicing the accounts of holders,  (xvi) any direct charges to holders approved
by the trustees of the Portfolio,  (xvii)  compensation and expenses of trustees
of the  Portfolio  who are not members of G/A's  organization,  and (xviii) such
non-recurring items as may arise, including expenses incurred in connection with
litigation,  proceedings  and  claims and the  obligation  of the  Portfolio  to
indemnify its trustees, officers and holders with respect thereto.

         In  consideration  of  the  services,  payments  and  facilities  to be
furnished  by G/A  under the  Agreement,  the  Portfolio  will pay G/A a monthly
advisory  as  described  under  Proposal  1 above.  Therefore,  there will be no
increase in the schedule of advisory fee rates as a result of the  conversion of
the Fund to the Hub and Spoke  structure  until  after one year and then only if
the Fund's  performance  merits an  adjustment.  The effective fee rate may also
decline from either growth in assets or performance that is below the benchmark.

         The  Agreement  provides  that it may be terminated at any time without
penalty on sixty days' notice by G/A or by the  trustees of the  Portfolio or by
vote of a majority of the outstanding  voting  securities of the Portfolio,  and
that it  shall  automatically  terminate  in the  event of its  assignment.  The
Agreement  provides  that G/A may render  services to others and engage in other
business activities. The Agreement also provides that G/A shall to be liable for
any loss incurred in connection  with the  performance of its duties,  or action
taken or omitted under the Agreement in the absence of willful misfeasance,  bad
faith or gross  negligence in the  performance of its duties or by reason of its
reckless disregard of its obligations and duties  thereunder,  or for any losses
which  may be  sustained  in the  acquisition,  holding  or  disposition  of any
security or other investment.

                                      Vote Required to Authorize the Fund to
                                     Approve the Investment Advisory Agreement

         Authorization  of  the  Fund  to  approve  the  Portfolio's  investment
advisory  agreement  with G/A at the meeting of the holders of  interests in the
Portfolio  requires the affirmative vote of a majority of the outstanding voting
securities of the Fund as defined in Proposal 1.

         The Board of Directors of the Fund recommends that the  stockholders of
the Fund vote to approve this Proposal.  In the event that the  stockholders  of
the Fund fail to approve this Proposal,  the Directors of the Fund will consider
what further action should be taken.

                                        PROPOSAL 3.  ELECTION OF DIRECTORS

         It is the  present  intention  that the  enclosed  proxy  will,  unless
authority to vote for election to office is  specifically  withheld by executing
the proxy in the manner stated thereon, be used for the purpose of voting to fix
the number of Directors for the ensuing year at six, and

                                                       20

<PAGE>



of voting in favor of the  election  of the  nominees  named  below  until their
successors are elected and qualified.  The nominee whose names is preceded by an
asterisk(*) is an  "interested  person" (as defined in the Act) by reason of his
affiliations  with Eaton Vance. The biographical  information as to each nominee
is provided under Proposal 2(A).

                                              Nominees for Directors

                                             Donald R. Dwight
                                            *James B. Hawkes
                                             Samuel L. Hayes, III
                                             Norton H. Reamer
                                             John L. Thorndike
                                             Jack L. Treynor

         As of July 18, 1996,  the proposed  Directors of the Fund  beneficially
owned shares constituting less than 1% of the outstanding shares of the Fund.

         It is not  expected  that any of the  nominees  referred  to above will
decline or become unavailable for election,  but in case this should happen, the
discretionary  power  given in the  proxy  may be used to vote for a  substitute
nominee or  nominees or to vote to fix the number of  Directors  for the ensuing
year at less than six (unless  authority to vote for election of all nominees is
specifically  withheld by  executing  the proxy in the manner  stated  thereon).
Eaton Vance has  undertaken  to use its best efforts to ensure that for at least
two years after  implementation of Proposal 1 at least 75% of the directors will
not be "interested persons" of the Eaton Vance organization or of G/A.

         In recommending a change in the Board,  the existing Board of Directors
considered various factors,  including the substantial  knowledge and experience
the  nominees  have  with  the  master-feeder  structure  and  the  Eaton  Vance
organization.  The existing Directors have resigned subject to implementation of
Proposals 1, 2A and 2B and the election of  successors.  The existing  Directors
and officers are:




Name and Other            Percentage Ownership     Principal Occupation
Information               of Shares Outstanding    Over Past Five Years

*Samuel D. Isaly                  2.48%            Chairman of the Board and
 Age: 51; director                                 President. President of G/A
 since 1989.                                       Capital Management, Inc.
                                                   since 1989; formerly Senior
                                                   Vice President of S.G.
                                                   Warburg & Co., Inc. from 1986
                                                   through 1989 and President of
                                                   Gramercy Associates, a health
                                                   care industry consulting
                                                   firm, from 1983 through 1986.

John J. Maggio, D.O.              0.06%            Director and Chairman of the
  Age: 53; director                                Department of Obstetrics and
  since 1989.                                      Gynecology at St. Clare's
                                                   Hospital since 1982; Clinical
                                                   Associate Professor of
                                                   Surgery at New York Medical
                                                   College since 1982; and
                                                   Clinical Associate Professor
                                                   of Obstetrics and Gynecology
                                                   at New York College of
                                                   Osteopathic Medicine since
                                                   1986.

Philip C. Smith                  0.00%             Private investor. Director of
  Age: 90; director                                other Capstone Funds and
  since 1989.                                      Lexington Mutual Funds.

Eugene E. Weise, M.D.,           0.30%             Private medical practice
P.C  Age: 57; director                             since 1972; formerly
  since 1989.                                      Assistant Professor of
                                                   Ophthalmology at Cornell
                                                   University School of Medicine
                                                   from 1974 through 1987.


*Edward L. Jaroski              0.01%              Vice President. Chairman of
  Age: 49; director                                the Board and Director of the
  since 1988.                                      Administrator since 1987;
                                                   President and Director of the
                                                   Distributor since 1987;
                                                   President and Director of
                                                   Capstone Financial Services,
                                                   Inc. since 1987;
                                                   Director/Trustee and Officer
                                                   of other Capstone Funds.

*Iris R. Clay                   0.00%              Secretary. Assistant
  Age: 44.                                         Secretary of Capstone
                                                   Financial Services, Inc.
                                                   since 1990; formerly
                                                   Compliance Analyst with
                                                   Capstone.

*Linda G. Giuffre               0.00%              Treasurer. Treasurer of
  Age: 34.                                         Capstone Financial Services,
                                                   Inc. since 1990; Treasurer of
                                                   other Capstone Funds;
                                                   formerly Transfer Agent
                                                   Manager with Capstone
                                                   Financial Services, Inc. from
                                                   1987 through 1990; Accounting
                                                   Supervisor with Tenneco
                                                   Financial Services, Inc. from
                                                   1984 through 1987.


* May be deemed to be an "interested Person" of the Fund as that term is defined
in the Investment  Company Act of 1940 because of his or her relationship to G/A
or Capstone.

         Each  Director  not  affiliated  with G/A is  entitled to $250 for each
Board  meeting  attended,  and is paid a $500 annual  retainer by the Fund.  The
Directors and officers of the Fund are also reimbursed for expenses  incurred in
attending meetings of the Board of Directors. For the fiscal year ending August

                                                       21

<PAGE>



31,  1996,  the Fund has paid or accrued  for the account of its  directors  and
officers, as a group for services in all capacities, a total of $4,250.

         The following table represents the fees paid or accrued during the 1996
calendar  year to the  directors  of the Fund and the  total  compensation  each
director received for the calendar year 1995 from the Capstone Funds complex.

                                             Aggregate       Total
                                             Compensation    Compensation
         Name                                From Fund       From Complex

Dr. John J. Maggio                           $ 1,500          $ 1,125
Philip C. Smith                                1,500            6,750
Dr. Eugene E. Weise                            1,250            1,000

     Messrs.  Maggio,  Smith  and  Weise  serve  as  members  of the  audit  and
nominating  committees.  During the current fiscal year, the audit committee had
one meeting and the nominating committee had no meetings. Each director attended
at least 75% of all Board and  committee  meetings for the year ended August 31,
1995.

                   4. RATIFICATION OF SELECTION OF ACCOUNTANTS
                                   OF THE FUND

         A  majority  of the  members  of each  Board of  Directors  who are not
interested persons of a Fund have selected Tait, Weller & Baker, Two Penn Center
Plaza, Suite 700, Philadelphia,  PA 191092-1707, as independent certified public
accountants  to sign or certify any financial  statements  which may be filed by
the Fund with the  Securities  and Exchange  commission in respect of all or any
part of the Fund's  fiscal year ending August 31, 1996,  the  employment of such
accountants being expressly conditioned upon the right of the Fund, by vote of a
majority of the outstanding capital stock at any meeting called for the purpose,
to terminate such employment  forthwith without any penalty.  Such selection was
made  pursuant  to  provisions  of Section  32(a) of the Act,  and is subject to
ratification  or  rejection by the  stockholders  at this  meeting.  The Fund is
informed  that no member  of Tait,  Weller & Baker  has any  direct or  material
indirect interest in the Fund.

         The Fund's independent  certified public accountants  provide customary
professional  services in  connection  with the audit  function for a management
investment  company  such  as  the  Fund,  including  services  leading  to  the
expression of opinions on the financial statements included in the Fund's annual
report to stockholders, opinions on financial statements and other data included
in the Fund's annual report to the Securities and Exchange Commission,  opinions
on  financial  statements  included  in  amendments  to the Fund's  registration
statement,  and  preparation of the Fund's  Federal tax returns.  The nature and
scope of the professional  services of the accountants have been approved by the
Fund's Board of Directors,  which has considered the possible  effect thereof on
the independence of the accountants.

         Representatives  of Tait, Weller & Baker are not expected to be present
at the meeting but have been given the  opportunity  to make a statement if they
so  desire  and will be  available  should  any  matter  arise  requiring  their
presence.


                                                       22

<PAGE>



         It is intended  that proxies not limited to the contrary  will be voted
in favor of ratifying the selection of Tait,  Weller & Baker, as the independent
certified  public  accountants  to be  employed  by the Fund to sign or  certify
financial  statements  required to be signed or certified by independent  public
accountants and filed with the Securities and Exchange  Commission in respect of
all or part of the fiscal year ending August 31, 1996.

                  PROPOSAL 5.  TO APPROVE THE ELIMINATION,
           SSIFICATION AND AMENDMENT OF THE FUND'S INVESTMENT OBJECTIVE
                  AND CERTAIN FUNDAMENTAL INVESTMENT POLICIES

         The Act requires a registered  investment company like the Fund to have
certain specific  investment policies which can be changed only by a shareholder
vote.  Investment companies may also elect to designate other policies which may
be changed only by a shareholder vote. Both types of policies are often referred
to as "fundamental"  policies. (In this Proxy Statement,  the word "restriction"
is sometimes  used to describe a policy.)  Some  fundamental  policies have been
adopted  in the past by the Fund to  reflect  certain  regulatory,  business  or
industry  conditions  which are no longer in effect.  Accordingly,  the Board of
Directors has approved the  simplification  and  modernization of those policies
which are required to be  fundamental,  and the  elimination as fundamental  any
policies  which are not required to be  fundamental  under the  positions of the
staff of the  Securities  and Exchange  Commission in  interpreting  the Act, in
which case, depending on the circumstances,  the policy would be reclassified as
a  nonfundamental  policy in the same or a modified  form,  or  eliminated.  The
revised policies must also be in conformity with state  securities  ("Blue Sky")
laws.   Nonfundamental   policies  can  be  changed  by  the  Directors  without
stockholder  approval.  Revision of  fundamental  policies have been approved by
shareholders of numerous other funds administered by EVM, and if these revisions
are approved  then the  uniformity  of such  policies  would serve to facilitate
EVM's compliance efforts.

         This Proposal seeks stockholder  approval of changes which are intended
to accomplish the foregoing  goals. The proposed changes will not affect current
management  of the Fund's  portfolio.  The proposed  changes to the  fundamental
policies  are  discussed  in detail  below.  Please  refer to the changes to the
policies  as set  forth in  Exhibit B (which  does not  include  the  additional
fundamental  investment  provision  to be added if Proposal 1 is  approved).  By
reducing to a minimum those  policies  which can be changed only by  stockholder
vote, the Fund may be able to avoid the costs and delay  associated  with future
stockholder  meetings and the Boards of Directors believes that G/A's ability to
manage the Fund's portfolio in a changing  regulatory or investment  environment
will be  enhanced.  Accordingly,  investment  management  opportunities  will be
increased.  The references to the Fund's investment  restrictions  correspond to
the  paragraphs  in Exhibit B. If this  Proposal is approved,  the  restrictions
would be reordered.




                                                       23

<PAGE>



             Reclassification and Amendment of Investment Objectives and
                           Basic Investment Policies

         The Fund's present investment  objectives and basic investment policies
are as follows:  "The Fund's primary objective is long-term growth of capital, a
goal it seeks by investing primarily in common stocks and securities  (including
debt and  warrants)  convertible  into common  stocks,  of domestic  and foreign
companies  engaged  in  medical  research  and the health  care  industry.  Such
companies  obtain at least  fifty  percent of their  profits and  revenues  from
medical  research  or health  care  products or  services.  Current  income is a
secondary  objective.  Except during temporary defensive periods,  not less than
65% of the Fund's total assets will be invested in the  securities  of companies
primarily engaged in medical research and the health care industry,  and, except
during temporary defensive periods,  the Fund would normally expect at least 80%
of its total assets to be so invested.  As a diversified  investment company, at
least 75% of the Fund's total  assets are required to be invested in  securities
limited in  respect  of any one  issuer to not more than 5% of the Fund's  total
assets and to not more than 10% of the issuer's voting securities."

         It is proposed  that the  investment  objective  be modified to express
more explicitly the focus on investing in of stocks of health science  companies
which in today's market  generally pay little or no dividends.  The proposed new
objective is: "long-term capital growth by investing in a global and diversified
portfolio of securities  of health  science  companies."  This  objective  would
remain  fundamental.  Similarly,  the 75%  diversification  restriction would be
retained as fundamental.  The remaining  policies would become  "nonfundamental"
and would be revised to be as follows:  "The  Portfolio  invests in a global and
diversified portfolio of securities of health science companies. These companies
principally  are  engaged in the  development,  production  or  distribution  of
products or services  related to scientific  advances in  healthcare,  including
biotechnology,   diagnostics,  managed  healthcare  and  medical  equipment  and
supplies,  and  pharmaceuticals.  At the time the Portfolio makes an investment,
50% or more of such a  company's  sales,  earnings  or assets will arise from or
will  be  dedicated  to  the  application  of  scientific  advances  related  to
healthcare.  Under normal market conditions,  the Portfolio will invest as least
65% of its assets in securities of health science  companies,  including  common
and preferred stocks;  equity interests in partnerships;  convertible  preferred
stocks;  and other  convertible  instruments".  These  changes  would be made to
improve the marketing  appeal of the Fund. The proposed changes would not affect
current portfolio management.

         Consistent  with these  changes  and the  inclusion  of the Fund in the
Eaton Vance family of funds,  the Board of Directors has changed the name of the
Fund  to  "EV   Traditional   Global  Health   Sciences  Fund"   effective  upon
implementation of Proposal 1.

                       Elimination of Certain Restrictions

      The Board of Directors proposes to delete Restriction (4) and most of
Restriction  (13) because such  restrictions  are not required to be fundamental
policies under the Act or state "Blue Sky" laws and/or the practices referred to
therein are otherwise governed by the Act.

                                                       24

<PAGE>




         Restriction  (4) concerning  investment in other  investment  companies
prohibits the Fund from  investing in securities of other  investment  companies
and investment funds.  Investment in other investment  companies is regulated by
the Act and this  restriction  does not contain all of the provisions in the Act
regarding such investments.

         The latter part of Restriction (13) concerning pledging,  mortgaging or
hypothecating  the assets of the Fund is being deleted as pledging  restrictions
are no longer required by state law.
Restriction (6), as revised, contains limitations on leverage.

                    Reclassification of Certain Restrictions

         The Board of Directors also proposes that  Restrictions  (7), (8), (9),
(10),  (14), and (17) and part of Restriction (16) be eliminated as fundamental,
but  be  retained  as  nonfundamental  policies  of the  Fund  (which  could  be
thereafter  changed or eliminated by Director vote). Each of these  restrictions
is required under various state "Blue Sky" laws and/or federal laws, but are not
required to be fundamental policies of the Fund.

         Restriction (7) concerning  investment in affiliated  issuers prohibits
the Fund from purchasing a security where  individuals  affiliated with the Fund
beneficially  own  more  than 5% of that  security.  The  securities  laws  have
numerous prohibitions on affiliated transactions and the restriction need not be
fundamental.

         Restriction  (8)  concerning  investing for control  prohibits the Fund
from investing for control or management of other  companies.  Such  investments
would be difficult because of the Act's diversification  requirements  contained
in  Restrictions  (10) and (11),  and are  regulated by the Act's  provisions on
affiliated  transactions.  Because the Fund focuses on health science companies,
amendment of the restriction if reclassified may be advisable in the future.

         Restriction  (9) concerns  investing in options and futures  contracts.
These transactions are of increasing use to portfolio  management and any future
need to permit greater use of them with appropriate prospectus disclosure, would
be facilitated by making this restriction nonfundamental.

         Restriction (10) concerning warrants and the middle part of Restriction
(16) concerning  investment in oil, gas and similar programs are not required to
be fundamental investment policies. No amendment is being proposed.

         Restriction  (14)  concerning  investment in  restricted  securities is
consistent (as revised) with the current position of the staff of the Securities
and Exchange  Commission.  The flexibility afforded to amend this restriction by
making it nonfundamental may be useful for a health science fund.


                                                       25

<PAGE>



         Restriction (17) concerns  investments in unseasoned  issuers with less
than three years continuous operation. This restriction is overly burdensome for
a health science fund and has been amended to permit 5% of total assets to be so
invested.

         As a result of this  proposed  reclassification  of certain  investment
restrictions  as  nonfundamental,  a future change in any of these  restrictions
could be effected by the Directors without stockholder approval if the Directors
determined  that  such  change  was  appropriate  and  desirable.  The  Board of
Directors has no present expectation that the foregoing restrictions which would
be reclassified would be amended or eliminated.  The Directors believe, however,
that this  reclassification of restrictions will permit the Fund to respond more
rapidly to future changes in the Fund's competitive and regulatory environment.

                        Amendment of Certain Restrictions

     The Board of Directors also proposes the amendment of seven fundamental
policies.

         Restriction (1) concerning underwriting is being amended to conform the
wording to that of other Eaton Vance administered funds. There is no substantive
change.

         Restriction (2) concerning  investments in real estate is being amended
in order to expressly  permit the Fund to invest in  securities  secured by real
estate and securities of companies which invest or deal in real estate,  both of
which were previously implied.

         Restriction (3) concerning  lending has been amended to reflect current
regulatory  restraints  and recent  changes to the lending policy of other Eaton
Vance administered funds. The Fund has no current expectation to lend securities
and is constrained by regulation as to the extent it could do so.

         The first  part of  Restriction  (5)  concerning  short  sales has been
revised to permit the Fund to engage in such  transactions  if they are "against
the box." In a short  sale,  the Fund  would  sell a  borrowed  security  with a
corresponding  obligation to return the same security. The revision would permit
such transactions only if the Fund owns or has the right to acquire the relevant
security.  Such transactions are not currently contemplated and would be engaged
in only if the  prospectus  is  revised.  The  latter  part of  Restriction  (5)
concerning margin  transactions has been clarified to permit expressly  ordinary
securities settlements practices.

         Restrictions  (6) and (13) concerning  senior  securities and borrowing
have been revised by permitting  borrowing and the issuance of senior securities
consistent  with the Act. The positions of staff of the  Securities and Exchange
Commission on borrowings and senior securities have evolved in recent years with
the  development  of new  investment  strategies,  such  as  reverse  repurchase
agreements and futures transactions. The Fund would like the ability to consider
use of new investment  techniques  consistent with the Act as interpretations of
the Act are further developed.


                                                       26

<PAGE>



         Finally, the wording of Restriction (16) with respect to commodities is
being amended to limit the exception to financial futures  contracts,  which was
previously implied.


                       Vote Required to Approve Proposal 5

     Approval of each item in this Proposal requires the affirmative vote of
a majority of the  outstanding  voting  securities  of the Fund as defined under
Proposal 1.  Implementation  of this  Proposal is not  dependent  upon any other
proposal herein.

         The Board of Directors has considered various factors and believes that
this Proposal will increase investment management flexibility and is in the best
interests  of the Fund's  stockholders.  If the  Proposal is not  approved,  the
Fund's present objectives and fundamental  policies and restrictions will remain
in effect and a stockholder  vote would be required before the Fund could engage
in activities  prohibited by a fundamental  restriction.  The Board of Directors
recommends   that  the   stockholders   vote  in   favor  of  the   elimination,
reclassification   and  amendment  of  the  Fund's  investment   objectives  and
restrictions as described above.

                              RELATED TRANSACTIONS

         The  proposed  restructuring  of the Fund  described  in Proposal 1 and
related changes described in this proxy statement are the result of the decision
of G/A and Eaton Vance to work jointly to improve the distribution,  performance
and  shareholder  servicing  of the  Fund.  To date,  these  organizations  have
formalized this relationship in three respects. First, Eaton Vance has agreed to
pay G/A on the conversion of the Fund to Hub and Spoke the sum of $2 million for
G/A's  tradename  which may  thereafter  only be used by G/A with Eaton  Vance's
approval  and such  approval  has only been given in  connection  with  services
provided by G/A to Eaton Vance.  In addition,  Eaton Vance has agreed to pay G/A
the sum of $500,000 if the assets of the Portfolio reach $100 million (excluding
any G/A  affiliated  investments)  within six  months  after  implementation  of
Proposal 1 as the result of the  services of G/A  personnel  in assisting in the
marketing of the restructured  Fund.  Lastly,  G/A has agreed to pay Eaton Vance
the  equivalent  of  one-third  of its  Portfolio  advisory  fee  out of its own
resources to be used by Eaton Vance to pay expenses related to its activities as
Placement Agent of the Portfolio. All of these agreements are designed to enable
Eaton  Vance to promote  the sale of Fund  shares and  increase  the size of the
Portfolio.  As  discussed in Proposal 1, asset growth  should be  beneficial  to
shareholders. It is possible G/A and Eaton Vance may enter into other agreements
that   directly  or  indirectly   affect  the  Fund,   but  none  are  currently
contemplated.

         G/A and Eaton  Vance have agreed to make  certain  payments to Capstone
for services  necessary to facilitate the transition of the  administration  and
distribution functions of the Fund and to provide incentives to Capstone to sell
shares  of  the  Fund.   G/A  will  pay  Capstone  the  sum  of  $150,000   upon
implementation  of  Proposal  1 and an amount  equal to .05% of the  Portfolio's
average daily net assets for two years.  (G/A and Eaton Vance will share equally
if such aggregate  payments exceed $200,000.) In addition,  if the assets of the
Portfolio reach $100

                                                       27

<PAGE>



million within six months of the implementation of Proposal 1 (excluding any G/A
affiliated investments),  G/A will pay Capstone $150,000. Eaton Vance has agreed
to reimburse  Capstone up to $75,000 for expenses of employment  severance  that
Capstone  incurs as a result of the change in Fund service  providers and to pay
Capstone $15,000 (plus  out-of-pocket  costs) for transition  related  services.
Capstone  will  become  a  dealer  firm in the  EVD  distribution  network  and,
therefore,  may receive  distribution  fees from EVD pursuant to the Fund's Rule
12b-1 distribution plan after the restructuring.

                      NOTICE TO BANKS AND BROKER/DEALERS

     The Fund has previously solicited all Nominee and Broker/Dealer accounts as
to the  number of  additional  proxy  statements  required  to supply  owners of
shares.  Should  additional  proxy material be required for  beneficial  owners,
please forward such requests to: Management  Information Systems, Inc. 61 Accord
Park Drive, Norwell, MA 02061.


                              ADDITIONAL INFORMATION

         The expense of preparing, printing and mailing this Proxy Statement and
enclosures  and the  cost of  soliciting  proxies  on  behalf  of the  Board  of
Directors of the Fund will be borne by Eaton Vance. Proxies will be solicited by
mail and may be  solicited in person or by telephone or telegraph by officers of
the Fund,  by personnel of G/A,  EVM, by  broker-dealer  firms or by  Management
Information  Systems,  Inc.,  a  professional  solicitation  organization.   The
expenses  connected with the  solicitation of these proxies and with any further
proxies which may be solicited by the Fund's officers,  by EVM's personnel or by
broker-dealer  firms,  in person,  by telephone or by telegraph will be borne by
Eaton Vance.  EVM will reimburse banks,  broker-dealer  firms, and other persons
holding shares registered in their names or in the names of their nominees,  for
their expenses  incurred in sending proxy material to and obtaining proxies from
the beneficial owners of such shares.

         All proxy cards  solicited by the Board of Directors  that are properly
executed and received by the tabulator  prior to the meeting,  and which are not
revoked,  will be voted at the meeting.  Shares represented by such proxies will
be voted in accordance with the  instructions  thereon.  If no  specification is
made on the proxy card, it will be voted for the matters  specified on the proxy
card. All proxies not voted,  will not be counted toward  establishing a quorum.
Broker  non-votes  will  be  counted  toward   establishing  a  quorum  and  for
determining  whether  sufficient  votes have been  received  for approval of the
Proposal to be acted upon.  Stockholders should note that while votes to abstain
will  count  toward  establishing  a  quorum,  passage  of  any  Proposal  being
considered  at the meeting will occur only if a  sufficient  number of votes are
cast for the Proposal. Accordingly, votes to abstain, broker non-votes and votes
against will have the same effect in determining whether a Proposal is approved.



                                                       28

<PAGE>



         In the event that sufficient  votes by the  stockholders of the Fund in
favor of any  Proposal  set forth in the Notice of this meeting are not received
by August 29, 1996,  the persons  named as  attorneys in the enclosed  proxy may
propose one or more  adjournments of the meeting to permit further  solicitation
of proxies.  A stockholder  vote may be taken on one or more of the Proposals in
this Proxy  Statement  prior to such  adjournment if sufficient  votes have been
received and it is otherwise appropriate.  Any such adjournment will require the
affirmative vote of the holders of a majority of the shares present in person or
by proxy at the session of the  meeting to be  adjourned.  The persons  named as
attorneys in the  enclosed  proxy will vote in favor of such  adjournment  those
proxies  which  they are  entitled  to vote in favor of the  Proposal  for which
further  solicitation  of proxies is to be made. They will vote against any such
adjournment those proxies required to be voted against such Proposal.  The costs
of any such additional  solicitation and of any adjourned  session will be borne
by the Fund.

         Consistent   with  applicable  law,  the  Fund  does  not  hold  annual
stockholders'  meetings.  Stockholders wishing to submit proposals for inclusion
in a proxy statement for a subsequent  meeting should send their proposal to the
Secretary  of the  Fund.  Proposals  must  be  received  in  advance  of a proxy
solicitation  to be  included  and the mere  submission  of a proposal  does not
guarantee  inclusion in the proxy statement  because certain federal  securities
law rules must be complied with.

         The Fund  will  furnish,  without  charge a copy of the  Fund's  Annual
Report and its most recent  Semi-Annual  Report  succeeding the Annual Report to
any  stockholder  upon request.  Stockholders  desiring to obtain a copy of such
reports  should  direct all  written  requests  to:  Capstone  Asset  Management
Company,  5847 San Felipe,  Suite 4100,  Houston,  Texas  77057,  or should call
Capstone at 1-800-262-6631.

                           MEDICAL RESEARCH INVESTMENT FUND, INC.

August 2, 1996

                                                       29

<PAGE>




                                                                 EXHIBIT A

                  WORLDWIDE HEALTH SCIENCES PORTFOLIO

                       INVESTMENT ADVISORY AGREEMENT


         AGREEMENT made this 24th day of June,  1996,  between  Worldwide Health
Sciences  Portfolio,  a New York trust (the "Trust") and G/A Capital Management,
Inc., a Delaware corporation (the "Adviser").

         1. Duties of the Adviser.  The Trust hereby  employs the Adviser to act
as investment  adviser for and to manage the investment and  reinvestment of the
assets of the Trust,  subject to the  supervision  of the Trustees of the Trust,
for the period and on the terms set forth in this Agreement.

         The Adviser hereby accepts such  employment and undertakes to afford to
the Trust the advice and assistance of the Adviser's  organization in the choice
of  investments  and in the purchase and sale of securities for the Trust and to
furnish  for  the  use of the  Trust  office  space  and  all  necessary  office
facilities,  equipment and personnel for servicing the  investments of the Trust
and to pay the  salaries  and fees of all officers and Trustees of the Trust who
are  members of the  Adviser's  organization  and all  personnel  of the Adviser
performing services relating to research and investment activities.  The Adviser
shall for all purposes herein be deemed to be independent contractors and shall,
except as otherwise  expressly provided or authorized,  have no authority to act
for or  represent  the Trust in any way or  otherwise  be deemed an agent of the
Trust.

         The Adviser shall provide the Trust with such investment management and
supervision as the Trust may from time to time consider necessary for the proper
supervision of the Trust. As investment  adviser to the Trust, the Adviser shall
furnish continuously an investment program and shall determine from time to time
what  securities  and  other  investments  shall  be  acquired,  disposed  of or
exchanged  and what  portion of the  Trust's  assets  shall be held  uninvested,
subject  always to the  applicable  restrictions  of the  Declaration  of Trust,
By-Laws and registration statement of the Trust under the Investment Company Act
of 1940,  all as from time to time amended.  Should the Trustees of the Trust at
any time, however,  make any specific  determination as to investment policy for
the Trust and notify the Adviser thereof in writing,  the Adviser shall be bound
by such  determination for the period, if any, specified in such notice or until
similarly notified that such  determination has been revoked.  The Adviser shall
take, on behalf of the Trust, all actions which they deem necessary or desirable
to implement the investment policies of the Trust.

         The  Adviser  shall  place  all  orders  for  the  purchase  or sale of
portfolio  securities  for the  account of the Trust  either  directly  with the
issuer or with brokers or dealers  selected by the Adviser,  and to that end the
Adviser  is  authorized  as the agent of the Trust to give  instructions  to the
custodian of the Trust as to deliveries  of securities  and payments of cash for
the account of the Trust.  In  connection  with the selection of such brokers or
dealers and the placing of such orders,  the Adviser  shall use its best efforts
to seek to execute security transactions at prices which are advantageous to the
Trust  and  (when  a  disclosed  commission  is  being  charged)  at  reasonably
competitive  commission  rates.  In  selecting  brokers or dealers  qualified to
execute a particular transaction, brokers or dealers may be selected who also


                                                      -30-          

<PAGE>



provide  brokerage and research  services (as those terms are defined in Section
28(e) of the Securities  Exchange Act of 1934) to the Adviser and the Adviser is
expressly authorized to pay any broker or dealer who provides such brokerage and
research services a commission for executing a security  transaction which is in
excess of the amount of commission  another  broker or dealer would have charged
for effecting that transaction if the Adviser determines in good faith that such
amount of commission is reasonable in relation to the value of the brokerage and
research services  provided by such broker or dealer,  viewed in terms of either
that particular  transaction or the overall  responsibilities  which the Adviser
and its  affiliates  have with  respect to  accounts  over  which they  exercise
investment  discretion.  Subject  to the  requirement  set  forth in the  second
sentence of this paragraph,  the Adviser is authorized to consider,  as a factor
in the  selection of any broker or dealer with whom  purchase or sale orders may
be placed,  the fact that such broker or dealer has sold or is selling shares of
any one or more  investment  companies  sponsored  by the  Adviser,  Eaton Vance
Management  or their  affiliates  or  shares  of any  other  investment  company
investing in the Trust.

         The Adviser  shall not be  responsible  for providing  certain  special
administrative  services  to  the  Trust  under  this  Agreement.   Eaton  Vance
Management,  in its capacity as Administrator of the Trust, shall be responsible
for  providing   such   services  to  the  Trust  under  the  Trust's   separate
Administration Agreement with the Administrator.

         2.  Compensation  of  the  Adviser.  For  the  services,  payments  and
facilities  to be  furnished  hereunder  by the  Adviser,  the Adviser  shall be
entitled to receive from the Trust a fee computed  daily and payable  monthly at
an  annual  rate of 1.00% of the  Trust's  average  daily  net  assets up to $30
million of such assets,  0.90% of the next $20 million of such assets, and 0.75%
on such assets in excess of $50  million.  For assets of $500  million and more,
the advisory fee is as follows:

                                                                    Annual
         Average Daily Net Assets                                  Asset Rate

         $500 million but less than $1 billion........................0.70%
         $1 billion but less than $1.5 billion. ......................0.65%
         $1.5 billion but less than $2 billion........................0.60%
         $2 billion but less than $3 billion..........................0.55%
         $3 billion and over..........................................0.50%

         After 12  months,  the  basic  advisory  fee is  subject  to  upward or
downward adjustment  depending upon whether,  and to what extent, the investment
performance  of the Trust  differs  by at least one  percentage  point  from the
record of the Standard & Poor's Index of 500 Common Stocks over the same period.
Each percentage point difference is multiplied by a performance  adjustment rate
of 0.025%.  The maximum  adjustment  plus/minus is 0.25%.  One twelfth (1/12) of
this  adjustment  is applied  each month to the average  daily net assets of the
Trust over the entire  performance  period.  This adjustment shall be based on a
rolling  period  of up to  and  including  the  most  recent  36  months.  Trust
performance  shall be  total  return  as  computed  under  Rule  482  under  the
Securities Act of 1933.

         Such advisory fee shall be paid monthly in arrears on the last business
day of each month.  The Trust's net asset value shall be computed in  accordance
with  the  Declaration  of Trust  of the  Trust  and any  applicable  votes  and
determinations  of  the  Trustees  of  the  Trust.  In  case  of  initiation  or
termination of the Agreement  during any month,  the fee for that month shall be
based on the number of calendar days during which it is in effect.



                                                      -31-              
<PAGE>



         The Adviser  may,  from time to time,  waive all or a part of the above
compensation to which it is entitled hereunder.

         3. Allocation of Charges and Expenses.  It is understood that the Trust
will pay all  expenses  other than those  expressly  stated to be payable by the
Adviser  hereunder,  which expenses payable by the Trust shall include,  without
implied  limitation,  (i) expenses of  maintaining  the Trust and continuing its
existence,  (ii)  registration of the Trust under the Investment  Company Act of
1940, (iii) commissions, fees and other expenses connected with the acquisition,
holding and  disposition  of securities  and other  investments,  (iv) auditing,
accounting and legal expenses,  (v) taxes and interest,  (vi) governmental fees,
(vii) expenses of issue, sale, and redemption of Interests in the Trust,  (viii)
expenses of  registering  and  qualifying  the Trust and  Interests in the Trust
under  federal  and  state   securities  laws  and  of  preparing  and  printing
registration  statements  or other  offering  statements  or memoranda  for such
purposes and for  distributing  the same to Holders and investors,  and fees and
expenses of registering  and maintaining  registrations  of the Trust and of the
Trust's  placement agent as  broker-dealer or agent under state securities laws,
(ix)  expenses  of reports and notices to Holders and of meetings of Holders and
proxy solicitations  therefor,  (x) expenses of reports to governmental officers
and commissions,  (xi) insurance  expenses,  (xii) association  membership dues,
(xiii) fees,  expenses and disbursements of custodians and subcustodians for all
services  to the  Trust  (including  without  limitation  safekeeping  of funds,
securities and other investments,  keeping of books,  accounts and records,  and
determination of net asset values, book capital account balances and tax capital
account  balances),  (xiv) fees,  expenses and disbursements of transfer agents,
dividend  disbursing  agents,  Holder  servicing  agents and  registrars for all
services to the Trust, (xv) expenses for servicing the account of Holders, (xvi)
any direct  charges to Holders  approved by the  Trustees  of the Trust,  (xvii)
compensation and expenses of Trustees of the Trust who are not members of one of
the Adviser's  organization,  and (xviii) such non-recurring items as may arise,
including  expenses  incurred in connection  with  litigation,  proceedings  and
claims and the  obligation of the Trust to indemnify its Trustees,  officers and
Holders with respect thereto.

         4. Other Interests.  It is understood that Trustees and officers of the
Trust and Holders of Interests  in the Trust are or may be or become  interested
in the  Adviser  as  trustees,  shareholders  or  otherwise  and that  trustees,
officers  and  shareholders  of the  Adviser  are or may be or become  similarly
interested in the Trust, and that the Adviser may be or become interested in the
Trust as Holder or otherwise.  It is also  understood  that trustees,  officers,
employees  and  shareholders  of the  Adviser  may be or become  interested  (as
directors,  trustees, officers,  employees,  shareholders or otherwise) in other
companies  or  entities   (including,   without  limitation,   other  investment
companies) which the Adviser or Eaton Vance Management may organize,  sponsor or
acquire, or with which it may merge or consolidate,  and that the Adviser or its
subsidiaries  or affiliates may enter into advisory or management  agreements or
other contracts or relationships with such other companies or entities.

         5. Limitation of Liability of the Adviser.  The services of the Adviser
to the Trust are not to be deemed to be  exclusive,  the  Adviser  being free to
render  services  to others  and  engage in other  business  activities.  In the
absence  of  willful  misfeasance,  bad  faith,  gross  negligence  or  reckless
disregard of  obligations  or duties  hereunder on the part of the Adviser,  the
Adviser  shall not be  subject  to  liability  to the Trust or to any  Holder of
Interests  in the Trust for any act or omission  in the course of, or  connected
with,  rendering  services hereunder or for any losses which may be sustained in
the acquisition, holding or disposition of any security or other investment.

     6.   Sub-Investment   Adviser.   The   Adviser   may  employ  one  or  more
sub-investment  advisers  from  time to time to  perform  such of the  acts  and
services  of the  Adviser,  including  the  selection  of  brokers or dealers to
execute the Trust's portfolio security transactions, and upon such terms and


                                                      -32-       

<PAGE>



conditions as may be agreed upon between the Adviser and such investment adviser
and  approved by the Trustees of the Trust,  all as permitted by the  Investment
Company Act of 1940.

         7. Duration and  Termination of this  Agreement.  This Agreement  shall
become  effective  upon the date of its  execution,  and,  unless  terminated as
herein  provided,  shall remain in full force and effect  through and  including
February  28,  1997 and shall  continue  in full force and  effect  indefinitely
thereafter,  but only so long as such  continuance  after  February  28, 1997 is
specifically  approved  at least  annually  (i) by the Board of  Trustees of the
Trust or by vote of a majority of the outstanding voting securities of the Trust
and (ii) by the vote of a majority  of those  Trustees  of the Trust who are not
interested  persons  of the  Adviser  or the  Trust  cast in person at a meeting
called for the purpose of voting on such approval.

         Any party  hereto may,  at any time on sixty (60) days'  prior  written
notice to the others,  terminate that party's obligations hereunder,  or, in the
case of the Trust, terminate this Agreement in its entirety, without the payment
of any penalty,  by action of Trustees of the Trust or the trustees or directors
of the  Adviser,  as the case may be, and the Trust  may,  at any time upon such
written  notice to the Adviser,  terminate  this  Agreement  with respect to the
Adviser by vote of a majority of the outstanding voting securities of the Trust.
This Agreement shall terminate automatically in the event of its assignment.

         8.  Amendments  of the  Agreement.  This  Agreement may be amended by a
writing  signed  by all  parties  hereto,  provided  that no  amendment  to this
Agreement  shall be  effective  until  approved (i) by the vote of a majority of
those Trustees of the Trust who are not interested  persons of an Adviser or the
Trust  cast in person  at a meeting  called  for the  purpose  of voting on such
approval, and (ii) by vote of a majority of the outstanding voting securities of
the Trust.

         9.  Limitation of Liability.  The Adviser  expressly  acknowledges  the
provision  in the  Declaration  of  Trust  of the  Trust  (Section  5.2 and 5.6)
limiting the personal  liability of the Trustees and officers of the Trust,  and
the Adviser  hereby  agrees that it shall have recourse to the Trust for payment
of claims or  obligations  as between the Trust and the  Adviser  arising out of
this  Agreement and shall not seek  satisfaction  from any Trustee or officer of
the Trust.

         10.  Certain  Definitions.   The  terms  "assignment"  and  "interested
persons" when used herein shall have the  respective  meanings  specified in the
Investment Company Act of 1940 as now in effect or as hereafter amended subject,
however,  to such  exemptions as may be granted by the  Securities  and Exchange
Commission by any rule, regulation or order. The term "vote of a majority of the
outstanding voting securities" shall mean the vote, at a meeting of Holders,  of
the lesser of (a) 67 per centum or more of the Interests in the Trust present or
represented by proxy at the meeting if the Holders of more than 50 per centum of
the  outstanding  Interests in the Trust are present or  represented by proxy at
the meeting, or (b) more than 50 per centum of the outstanding  Interests in the
Trust.  The terms  "Holders"  and  "Interests"  when used herein  shall have the
respective meanings specified in the Declaration of Trust of the Trust.




                                                      -33-        
<PAGE>



         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed on the day and year first above written.

WORLDWIDE HEALTH SCIENCES PORTFOLIO

         /s/  James B. Hawkes
By:
         President


G/A CAPITAL MANAGEMENT, INC.

         /s/ Samuel D. Isaly
By:
         President


                                                      -34-         
<PAGE>



                                                                 EXHIBIT B

                                              INVESTMENT RESTRICTIONS

         [Proposed Additions in Italics and Proposed Deletions in Brackets]

         As a matter of fundamental policy, the Fund may not:

         1.       [Act as an  underwriter  of]  Underwrite  securities  of other
                  issuers  [within  the  meaning of the  Securities  Act of 1933
                  except insofar as it might be deemed to be an underwriter upon
                  disposition of certain  portfolio  securities  acquired within
                  the limitation on purchases of restricted securities];

         2.       [Engage] Invest in [the purchase or sale of interests in] real
                  estate including interests in real estate limited partnerships
                  (although  it may  purchase  and  sell  securities  which  are
                  secured  by real  estate and  securities  of  companies  which
                  invest  or deal in  real  estate)  [or  real  estate  mortgage
                  loans];

         3.       Make  loans to any  person,  except  by (a) [that the Fund may
                  purchases  or hold] the  acquisition  of debt  securities  and
                  making portfolio  investments  [instruments in accordance with
                  its  investment  objectives  and policies,  and may enter] (b)
                  entering into repurchase  agreements and (c) lending portfolio
                  securities;

         4.       [Acquire securities of other investment companies registered 
                  under the Investment Company Act of 1940, except in connection
                  with a merger, consolidation, reorganization or acquisition of
                  assets];

         5.       Sell  securities  short  unless  at all  times  when  a  short
                  position is open the Fund either owns an equal  amount of such
                  securities   or   owns   securities    convertible   into   or
                  exchangeable,  without  payment of any further  consideration,
                  for  securities  of the same issue as, and equal in amount to,
                  the  securities  sold short,  or purchase  any  securities  on
                  margin except that the Fund may obtain such short-term credits
                  as may be necessary  for the  clearance of purchases and sales
                  of  securities  [may enter into futures  contracts and related
                  options];

         6.       Issue any senior securities except as permitted by the 
                  Investment Company Act of 1940 [that the Fund may enter into 
                  futures contracts and related options];

         7.       *Purchase  or retain  the  securities  of any issuer if to the
                  knowledge  of the Fund any  officer or director of the Fund or
                  of its investment adviser own beneficially more than 1/2 of 1%
                  of the outstanding securities of such issuer and together they
                  own  beneficially  more  than  5% of the  securities  of  such
                  issuer;

         8.       *Invest in companies for the purpose of exercising control or
                  management;

         9.       *Invest  in or sell  put  options,  call  options,  straddles,
                  spreads or any combination  thereof,  except that the Fund may
                  write  covered  call  options or enter into  closing  purchase
                  transactions  and except that the Fund may enter into  futures
                  contracts and related options; or



- --------
 *This restriction would become nonfundamental if Proposal 5 is approved.


                                                      -35-                    

<PAGE>



         10.      *Invest in  warrants  if as a result more than 2% of the value
                  of the Fund's total assets would be invested in warrants which
                  are not listed on a recognized stock exchange, or more than 5%
                  of the Fund's  total  assets  would be  invested  in  warrants
                  regardless of whether listed on such an exchange;

         11.      With respect to 75% of its total assets, invest more than 5% 
                  of its assets in the securities of any one issuer (except 
                  securities issued or guaranteed by the U.S. Government, its
                  agencies and instrumentalities);

         12.      With respect to 75% of its total assets, invest in the 
                  securities of any issuer if as a result the Fund holds more 
                  than 10% of the outstanding securities of such issuer;

         13.      Borrow money except as permitted by the Investment Company Act
                  of 1940 [or pledge,  mortgage or hypothecate its assets except
                  to  facilitate   redemption  requests  which  might  otherwise
                  require untimely  disposition of portfolio securities and then
                  only from banks and in amounts not exceeding the lessor of 10%
                  of its total  assets  valued at cost or 5% of its total  asset
                  valued  at  market  at the  time  of such  borrowing,  pledge,
                  mortgage or  hypothecation  and except that the Fund may enter
                  into futures contracts and related options];

         14.      *Invest  more than [10% of the value] 15% of its net assets in
                  [illiquid]   securities  which  are  not  readily  marketable,
                  including  repurchase  agreements with remaining maturities in
                  excess of seven days and  securities  and  [other]  restricted
                  securities  [for  which  market  quotations  are  not  readily
                  available.]  Restricted  securities  for the  purposes of this
                  limitation  do not  include  securities  eligible  for  resale
                  pursuant  to Rule 144A  under the  Securities  Act of 1933 and
                  commercial  paper issued  pursuant to Section 4(2) of said Act
                  that the Board of  Directors of the Fund,  or their  delegate,
                  determines to be liquid.

         15.      Invest  in the  securities  of any one  industry,  except  the
                  medical   research  and  health  care   industry  (and  except
                  securities  issued or guaranteed by the U.S.  Government,  its
                  agencies and  instrumentalities)  if as a result more than 25%
                  of the Fund's total assets would be invested in the securities
                  of such industry;

         16.      *Purchase or sell commodities or commodity contracts with 
                  respect to physical commodities, or invest in oil, gas or 
                  mineral exploration or development programs [except that the 
                  Fund may enter into futures contracts and related options]; 
                  and

         17.      *Invest   in  the   securities   of  any   issuer   (including
                  predecessors)  which has not been in continuous  operation for
                  at least  three  years  if more  than 5% of the  Fund's  total
                  assets would be invested in such securities.







- --------
  * This restriction would become nonfundamental if Proposal 5 is approved.



                                                      -36-           
<PAGE>



MEDICAL RESEARCH INVESTMENT FUND, INC................THIS PROXY IS SOLICITED ON
                                                     BEHALF OF THE BOARD OF 
                                                     DIRECTORS OF THE FUND

KNOW ALL MEN BY THESE PRESENTS: That the undersigned,  revoking previous proxies
for such stock,  hereby appoints Samuel D. Isaly and James B. Hawkes,  or any of
them, attorneys of the undersigned, with full power of substitution, to vote all
stock of Medical  Research  Investment  Fund,  Inc.,  which the  undersigned  is
entitled to vote at the Special  Meeting of the  Stockholders of said Fund to be
held on August 29, 1996 at the offices of  Shearman &  Sterling,  599  Lexington
Avenue,  New York,  New York, at 2:00 P.M.  (Eastern  time),  and at any and all
adjournments  thereof.  Receipt  of the Notice of and Proxy  Statement  for said
Meeting is acknowledged.

The shares  represented by this proxy will be voted on the following  matters as
specified below and on the reverse side by the undersigned.  If no specification
is made, this proxy will be voted in favor of all such matters. Note: This proxy
must be returned in order for your shares to be voted.

1.  To approve a new investment policy
    and to supplement investment
    restrictions to permit a new
    investment structure as described
    in the Proxy Statement.              FOR [ ]   AGAINST [ ]   ABSTAIN [ ]1

2.A. To authorize the Fund to vote at
     a meeting of holders of interests
     in the Portfolio to elect six 
     trustees of the Portfolio.        FOR [ ]                 WITHHOLD [ ] 2A
                                       the nominees            AUTHORITY
                                       except those whose      to vote for any
                                       names are inserted on   of the nominees.
                                       the line below. 

     D.R. Dwight, J.B. Hawkes, S.L.Hayes, III, N.H. Reamer, J.L.Thorndike,
     J.L.Treynor.



2.B. To authorize the Fund to vote
     at a meeting of holders of 
     interests in the Portfolio to
     approve the Investment Advisory
     Agreement between the Portfolio 
     and G/A Capital Management, Inc. 
     as set forth in Exhibit A to    
     the Proxy Statement.               FOR [ ]   AGAINST [ ]   ABSTAIN [ ]2B 

3.   To fix the number of Directors
     at six, and to elect Directors.    FOR [ ]                WITHHOLD [ ]3   
                                       the nominees            AUTHORITY
                                       except those whose      to vote for any
                                       names are inserted on   of the nominees.
                                       the line below.

    Directors - D.R. Dwight, J.B. Hawkes,
    S.L. Hayes, III, N.H. Reamer, J.L. Thorndike,
    J.L. Treynor     


4. To ratify the selection of Tait, 
   Weller & Baker as independent public
   accountants of the Fund for the current
   fiscal year.                          FOR [ ]   AGAINST [ ]   ABSTAIN [ ]4




                                                      -37-             
<PAGE>


5. To approve the revision of the 
   Fund's investment objective and certain
   of the Fund's investment policies 
   as set forth in Exhibit B to the
   Proxy Statement as follows:

5.A. Reclassification and Amendment 
     of the investment objective 
     and basic policies.               FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5A
5.B. Eliminate the restriction
     concerning investment in 
     other investment companies.       FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5B
5.C. Eliminate the restriction 
     concerning pledging.              FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5C
5.D. Reclassify the restriction 
     concerning investment in 
     affiliated issuers.               FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5D
5.E. Reclassify the restriction 
     concerning investing for control. FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5E
5.F. Reclassify the restriction 
     concerning options and futures.   FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5F
5.G. Reclassify the restriction 
     concerning warrants.              FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5G
5.H. Reclassify the restriction 
     concerning exploration programs.  FOR [ ]   AGAINST [ ]    ABSTAIN [ ]5H
5.I. Reclassify and amend the 
     restriction concerning illiquid 
     securities.                       FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5I
5.J. Reclassify and amend the restriction 
     concerning unseasoned issuers.    FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5J
5.K. Amend the restriction concerning
     underwriting.                     FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5K
5.L. Amend the restriction concerning 
     real estate.                      FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5L
5.M. Amend the restriction concerning 
     lending.                          FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5M
5.N. Amend the restriction concerning
     short sales.                      FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5N
5.O. Amend the restriction concerning 
     senior securities.                FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5O
5.P. Amend the restriction concerning 
     borrowing.                        FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5P
5.Q. Amend the restriction concerning
     commodities.                      FOR [ ]    AGAINST [ ]    ABSTAIN [ ]5Q

As to any other matter,  or if any of the nominees named in the Proxy  Statement
are not available for election,  said  attorneys  shall vote in accordance  with
their judgment.

THE BOARD OF DIRECTORS
RECOMMENDS A VOTE
IN FAVOR OF ALL MATTERS
- ---------------

 ............................................................


 ............................................................

Please sign exactly as your name
or names appear at left.

Dated:
, 1996
- --------------------



- -38- 


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