MEDICAL RESEARCH INVESTMENT FUND INC
497J, 1996-01-17
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                       MEDICAL RESEARCH INVESTMENT FUND, INC.

                                    CERTIFICATION


          The undersigned, Vice President of Medical Research Investment
Fund, Inc., a Maryland corporation (the "Fund"), hereby certifies that:

          (a)  The form of Prospectus and Statement of Additional
               Information that would have been filed pursuant to Rule
               497(c) of the Securities Act of 1933, as amended, would not
               have differed from that contained in Post-Effective
               Amendment No. 14 to the Registration Statement of the Fund.

          (b)  The text of Post-Effective Amendment No. 14 to the
               Registration Statement of the Fund has been filed
               electronically.

          IN WITNESS WHEREOF, the undersigned has signed and delivered this
Certification as of the 16th day of January, 1996.



                                /s/EDWARD L. JAROSKI                   
                                --------------------------------
                                Edward L. Jaroski
                                Vice President



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