PHOTOGEN TECHNOLOGIES INC
PRE 14A, 2000-04-07
PHARMACEUTICAL PREPARATIONS
Previous: WLR FOODS INC, 4, 2000-04-07
Next: MANUFACTURERS LIFE INSURANCE CO OF NORTH AMERICA, POS AM, 2000-04-07



<PAGE>

                                  SCHEDULE 14A
                                 (RULE 14A-101)
                     INFORMATION REQUIRED IN PROXY STATEMENT
                            SCHEDULE 14A INFORMATION
                  Proxy Statement Pursuant to Section 14(A) of
                       the Securities Exchange Act of 1934

/X/  Filed by the Registrant

/ /  Filed by a Party other than the Registrant

Check the appropriate box:

/X/  Preliminary Proxy Statement

/ /  Confidential, for use of the Commission only (as permitted by Rule 14a-6(e)
     (2))

/ /  Definitive Proxy Statement

/ /  Definitive Additional Materials

/ /  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                           PHOTOGEN TECHNOLOGIES, INC.
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

/X/  No Fee Required

/ /  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and
     0-11.

              (1)  Title of each class of securities to which
                   transaction applies:

              (2)  Aggregate number of securities to which transaction
                   applies:
                            -------------------------------------------

              (3)  Per unit price or other underlying value of
                   transaction computed pursuant to Exchange Act Rule 0-
                   11 (set forth the amount on which the filing fee is
                   calculated and state how it was determined:

                   ----------------------------------------------------

              (4)  Proposed maximum aggregate value of transaction:

                   ----------------------------------------------------

              (5)  Total fee paid:
                                      -------------------------------------

/ /  Fee paid previously with preliminary materials.

/ /  Check box if any part of the fee is offset as provided by Exchange
     Act Rule 0-11(a)(2) and identify the filing for which the offsetting
     fee was paid previously. Identify the previous filing by registration
     statement number, or the Form or Schedule and the date of its filing.

              (1)  Amount Previously Paid:
                                          ------------------------------

              (2)  Form, Schedule or Registration Statement No.:
                                                                --------

              (3)  Filing Party:
                                ----------------------------------------

              (4)  Date Filed:
                              ------------------------------------------

<PAGE>

[GRAPHIC OMITTED]

NOTICE OF 2000 ANNUAL MEETING
OF STOCKHOLDERS AND PROXY STATEMENT

                                                                  April 19, 2000

         The 2000 annual meeting of stockholders of Photogen Technologies, Inc.,
a Nevada corporation (the "Company"), will be held on Wednesday, May 17, 2000,
at 10:00 a.m., Chicago time, at the Ritz Carlton Hotel, 160 East Pearson Street,
Chicago, Illinois. The purposes of the meeting are to:

         1.  Elect six directors;

         2.  Approve an Amendment to Article Fifth of the Company's
             Articles of Incorporation increasing the size of the Board of
             Directors from six to seven directors and providing that all
             vacancies on the Board of Directors shall be filled in the
             manner provided in the Company's Bylaws;

         3.  Approve the 2000 Long Term Incentive Compensation Plan;

         4.  Ratify the appointment of BDO Seidman, LLP as the Company's
             independent certified public accountants for 2000; and

         5.  Transact such other business as may properly come before the
             meeting or any adjournment.

         Stockholders are cordially invited to attend the meeting. IF YOU PLAN
TO ATTEND, PLEASE NOTIFY THE COMPANY BY MAY 5, 2000. Space is limited. Only
stockholders of record at the close of business on April 17, 2000 will be
entitled to notice of the annual meeting and to vote at the meeting or any
adjournment. A list of stockholders of the Company entitled to vote at the
meeting will be available for inspection by stockholders at the Company's
office, for ten days before the annual meeting during normal business hours.

         PLEASE COMPLETE, DATE, SIGN AND RETURN THE ENCLOSED PROXY CARD IN THE
ENVELOPE PROVIDED, WHICH REQUIRES NO POSTAGE IF MAILED IN THE UNITED STATES. IF
YOU DECIDE TO ATTEND THE MEETING, YOU MAY, IF DESIRED, REVOKE THE PROXY AND VOTE
THE SHARES IN PERSON. ATTENDANCE AT THIS MEETING DOES NOT ITSELF SERVE TO REVOKE
YOUR PROXY.

                                         By Order of the Board of Directors,

                                         ERIC A. WACHTER, PH.D.

                                         SECRETARY

<PAGE>

                           PHOTOGEN TECHNOLOGIES, INC.
                         7327 OAK RIDGE HIGHWAY, SUITE B
                               KNOXVILLE, TN 37931

                                 PROXY STATEMENT
                                       FOR
                       2000 ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON MAY 17, 2000

GENERAL INFORMATION

         Photogen Technologies, Inc. ("we," "us," "our," or the "Company") is
furnishing this Proxy Statement to holders of its common stock, par value $.001
per share ("Common Stock"), in connection with the solicitation of Proxies on
behalf of the Company's Board of Directors for the Annual Meeting of
Stockholders to be held at 10:00 a.m. Chicago time on Wednesday, May 17, 2000
(the "Annual Meeting"). The Annual Meeting will be held at the Ritz Carlton
Hotel, 160 East Pearson Street, Chicago, Illinois.

         SHAREHOLDERS ENTITLED TO VOTE. Only stockholders of record at the close
of business on April 17, 2000 are entitled to notice of and to vote at the
Annual Meeting. Stockholders will be solicited by mail on or about April 20,
2000. On all matters that may come before the Annual Meeting, each holder of
Common Stock will be entitled to one vote for each share of Common Stock he or
she holds at the close of business on April 17, 2000; and each holder of Series
B Convertible Preferred Stock ("Series B Preferred") will be entitled to the
number of votes equal to the number of shares of Common Stock into which such
holder's Series B Preferred is convertible as of April 17, 2000. The holders of
a majority of the shares of voting stock entitled to vote and present in person
or represented by proxy will constitute a quorum at the Annual Meeting.
Abstentions and broker non-votes will be counted for purposes of determining the
presence of a quorum; but will not be counted to determine whether any given
proposal has been approved by the stockholders. A broker "non-vote" occurs when
a nominee holding shares for a beneficial owner does not vote on a particular
proposal because the nominee does not have discretionary voting power with
respect to that item and has not received instructions from the beneficial
owner. At April 1, 2000 there were 37,383,386 shares of Common Stock
outstanding; and 337,056 shares of Series B Preferred outstanding which are
convertible into 337,056 shares of Common Stock as of April 1, 2000.

         We are the record holder of 22,955 shares of Common Stock (less than
0.1% of the outstanding Common Stock) as exchange agent for stockholders who
have not turned in their shares of our predecessor (Bemax Corporation) in
exchange for Company shares with respect to previous reverse splits of the
Common Stock. Proxy materials will be delivered to the last known addresses of
those stockholders. If any of those stockholders votes at the Annual Meeting (by
Proxy or attending the Annual Meeting), we will record their votes in accordance
with their direction. We will treat shares held by such stockholders who do not
vote as broker non-votes.

         HOW TO VOTE. Please sign, date and return the enclosed Proxy promptly.
If your shares are held in the name of a bank, broker or other holder of record
(that is, in "street name") you will receive instructions from the holder of
record that you must follow for your shares to be voted. The Board of


                                     -1-
<PAGE>

Directors recommends that you vote FOR each of the four proposals to be
considered in the Annual Meeting.

         CHANGING YOUR VOTE. Returning your completed Proxy will not prevent you
from voting in person at the Annual Meeting if you are present and wish to vote.
You may attend the Annual Meeting, revoke your Proxy and vote in person if you
desire to do so, but attending the Annual Meeting will not by itself revoke your
Proxy. If your shares are held in the name of a bank, broker or other holder of
record, you must obtain a proxy, executed in your favor, from the holder of
record to be able to vote at the Annual Meeting. You may revoke your Proxy at
any time before it is exercised by either giving written notice of revocation to
the Company's Secretary or by submitting a new Proxy dated after the revoked
Proxy to us before the Annual Meeting.

         Shares represented by executed Proxies that are not revoked will be
voted in accordance with the instructions in the Proxy or, in the absence of
instructions, in accordance with the recommendations of the Board of Directors.
The election of directors requires a plurality of the votes cast by the holders
of the voting stock. A "plurality" means that the individuals who receive the
largest number of affirmative votes cast are elected as directors up to the
maximum number of directors to be chosen at the Annual Meeting. The affirmative
vote of the holders of a majority of the voting stock present in person or
represented by proxy and entitled to vote is required to approve any other
matter to be acted upon at the Annual Meeting.

         PROXY SOLICITATION. We will pay all expenses of the solicitation,
including the cost of preparing, assembling and mailing the proxy solicitation
materials. We expect to reimburse brokerage houses, custodians, nominees and
fiduciaries on request for reasonable out-of-pocket expenses they incur in
connection with forwarding solicitation material to the beneficial owners of our
stock.

         DISSENTERS' RIGHTS OF APPRAISAL. There are no dissenters' rights of
appraisal in connection with the matters to be voted on at the Annual Meeting.

         STOCKHOLDER PROPOSALS. Stockholders interested in presenting a proposal
for consideration at our annual meeting of stockholders in 2001 may do so by
following the procedures prescribed in Rule 14a-8 under the Securities Exchange
Act of 1934 and our Bylaws. To be eligible for inclusion, stockholder proposals
must be received by the Company's Corporate Secretary no later than December 31,
2000.

                                   PROPOSAL 1

                            ELECTION OF SIX DIRECTORS
                       TO THE COMPANY'S BOARD OF DIRECTORS

         DIRECTOR NOMINEES

         There are six nominees for election as directors of the Company, each
of whom will hold office until the next annual meeting of shareholders and until
his successor is elected and qualified, or until his earlier death, retirement,
resignation or removal. Three of the Company's six incumbent directors, Eric
Wachter, Ph.D., Robert Weinstein, M.D. and Lester McKeever, Jr., are nominated
for re-election. In addition to the three incumbent directors nominated for
re-election, Theodore Tannebaum, Eugene Golub


                                       -2-
<PAGE>

and Vincent L. Fabiano are nominated for election as directors of the Company.
Except for Mr. McKeever, none of these individuals is a director of any other
company subject to the reporting requirements under the federal securities laws.

         Upon election of the six directors currently nominated for election to
the Board of Directors, there will be one director position vacant. We are
currently conducting a search for a new President and CEO, and the Board intends
to appoint this individual to the Board of Directors when selected.

         A brief discussion of the business experience of each director and
director nominee during the past five years is set forth below.

         VINCENT L. FABIANO, age 47, has been Vice President of Corporate
Development at Elan Pharmaceutical Technologies, Inc. since August 1998. Prior
to that time he was Executive Vice President and Chief Operating Officer of
Transcell Technologies, a pharmaceutical company and Vice President of Business
Development at Sepracor, also a pharmaceutical company. Mr. Fabiano received a
law degree from the University of Houston and a Bachelor of Science in Pharmacy
from the University of Maryland College of Pharmacy.

         EUGENE GOLUB, age 69, has served as Chairman of Golub & Company, a
company he founded in 1961, which with its affiliates has been involved in more
than $2 billion in real estate transactions. Under Mr. Golub's leadership, the
Golub companies have owned, developed or operated more than 25 million square
feet of office, residential and mixed-use properties in the United States and
abroad. Mr. Golub is active in numerous Chicago based charitable organizations
and was inducted into the Chicago Association of Realtors Hall of Fame in 1999.

         LESTER H. MCKEEVER, JR., age 65, has served as a Director of the
Company since June 17, 1998. Mr. McKeever is Managing Principal of the firm of
Washington, Pittman & McKeever, LLC, a Chicago, Illinois firm of certified
public accountants and consultants providing a broad range of professional
services, and has held a similar position with that firm since 1976. Mr.
McKeever is also Chairman of the Federal Reserve Bank of Chicago, and he serves
as a director of MBIA Insurance Corp. of Illinois, Worldwide Broadcasting, Inc.,
People's Energy Corporation, and Printing Specialities, Inc. Mr. McKeever serves
on several not-for-profit boards and councils, including the Chicago Urban
League (formerly Chairman of the Board), Business Advisory Counsel University of
Illinois College of Commerce at Urbana-Champaign, University of Illinois Board
of Trustees (Treasurer), Illinois Institute of Technology, IIT Chicago Kent
College of Law, and the Chicago Symphony Orchestra Association. Mr. McKeever
received his B.S. degree in accounting from the University of Illinois at
Urbana- Champaign and his J.D. with distinction from the IIT-Chicago Kent
College of Law.

         THEODORE TANNEBAUM, age 66, was Chairman of the Board of HMO America,
Inc. and is currently a private investor. During the last five years, Mr.
Tannebaum has also been involved in the development and production of films and
other theatrical productions through Lakeshore Entertainment Film Production Co.
of which he is Chairman of the Board. He received a law degree from DePaul
University and a business degree from Roosevelt University, both in Chicago,
Illinois.

         ERIC A. WACHTER, Ph.D., age 37, has served as a Director, Secretary and
employee of the Company since May 16, 1997, and he was appointed as a Vice
President in 1999. He is primarily responsible for developing and demonstrating
the functional feasibility of the laser system hardware,


                                       -3-
<PAGE>

including focusing and targeting. He is also responsible for development of
nontherapeutic laser applications. He received a Ph.D. in chemistry from the
University of Wisconsin-Madison and a B.S. in chemistry (cum laude) in the
honors program from Indiana University, Bloomington. Dr. Wachter is one of the
founders of Photogen L.L.C. and for the three years prior to May 1997 he was
associated with the Oak Ridge National Laboratory. Dr. Wachter is a
physical-analytical chemist who concentrates in the fields of biochemistry,
optical spectroscopy and instrumentation research and development. He has
numerous technical publications in these fields along with numerous U.S.
Patents, patent applications and patent disclosures.

         ROBERT J. WEINSTEIN, M.D., age 54, has served as a Director of the
Company since February 28, 1997. He is currently a private investor. During the
last five years, Dr. Weinstein served as Chief Executive Officer of HMO America,
Inc. and subsequently held the same position in United HealthCare of Illinois
when United HealthCare acquired HMO America in 1993. On January 1, 1996 he
became a consultant to United HealthCare Corporation. He is a graduate of the
Chicago Medical School and received a B.A. from Hunter College in New York.

         EXECUTIVE OFFICERS AND SIGNIFICANT EMPLOYEES

         The recent business experience of our other executive officers and
significant employees follows.

         TIMOTHY SCOTT, Ph.D., age 42, has served as the Company's Interim
President, CEO, Chief Financial Officer and Treasurer since February 2000 and as
an employee of the Company since November 1, 1997. Dr. Scott is one of the
founders of Photogen, L.L.C. and prior to 1997 he was associated with Oak Ridge
National Laboratory. Dr. Scott has experience in the fields of chemical
separations, material science, and biotechnology. He has numerous technical
publications in these fields, over ten U.S. patents, and has licensed
separations technology for petrochemical processing, solvent extraction, and
analytical chemistry applications. Dr. Scott has a Ph.D. in chemical engineering
from the University of Wisconsin-Madison, and a B.S. in chemical engineering
from the University of Tennessee-Knoxville.

         GERALD L. WOLF, Ph.D., M.D., age 62, has served as the Company's
Medical Director since July 1999. For the five years prior to that time he
served as a Director of the Center of Imaging and Pharmaceutical Research at
Massachusetts General Hospital and as a professor at Harvard Medical School. Dr.
Wolf is a leading researcher in the field of interventional radiology whose
primary research focus has been non-invasive and minimally invasive cancer
treatments. He is the author of numerous articles in peer-reviewed journals, and
is an inventor with respect to five world-wide patents. Dr. Wolf graduated from
Harvard Medical School and received his B.S., M.S. in Physiology and Ph.D. in
Physiology and Pharmacology all from the University of Nebraska.

         DAVID D. SHAW, Ph.D., age 57, has served as the Company's Vice
President of Clinical Research and Technology Development since November 1999.
Dr Shaw is responsible for directing clinical trial programs leading to Food and
Drug Administration (FDA) approval of the Company's advanced device and drug
technologies. For eight years prior to Dr. Shaw joining the Company, he was Vice
President of Drug Development for Latin America and Canada for Nycomed Amersham
Inc., a pharmaceutical company. Dr. Shaw holds a bachelor's degree in zoology
from the University of Cincinnati, a Master's


                                       -4-
<PAGE>

Degree in Biology from Idaho State University, and a Ph.D. in Medical Physiology
and Biophysics from the University of Nebraska Medical Center.

         JAY ZIMMERMAN, M.Ed., age 39, has served as the Company's Vice
President of Clinical Operations since November 1999. For two years prior to
that time, Mr. Zimmerman was Chief Operating Officer for Clinical Trials and
Senior Vice President of WorldCare, Inc. and from 1990 through 1998 he served as
Administrative Director of the Oral and Maxillofacial Surgery Department and of
the Center for Imaging and Pharmaceutical Research at Massachusetts General
Hospital. Mr. Zimmerman received a B.S. in Biology and Education from the
University of South Carolina and a Master of Education in Administrative
Policies Studies and Hospital Administration from the University of Pittsburgh.

         DIRECTOR'S MEETINGS AND COMMITTEES

         During the 1999 fiscal year, the Board of Directors held five meetings
and acted by unanimous written consent on seven occasions. The Executive
Committee did not hold any meeting or act by unanimous written consent during
the 1999 fiscal year. No incumbent director attended fewer than 75% of all
meetings of the Board of Directors, or fewer than 75% of all meetings of a
committee on which that director served during the past fiscal year.

         The Board of Directors has a standing Audit Committee and Compensation
Committee. Dr. Weinstein and Mr. McKeever have been members of the Company's
Audit Committee and Compensation Committee since the formation of those
Committees on June 17, 1998, and they are expected to continue in those
capacities. The Audit Committee has general responsibility for meeting with the
Company's independent public accountants and reviewing the scope and results of
auditing procedures and our accounting procedures and controls. The Audit
Committee also provides general oversight with respect to the accounting
principles employed in our financial reporting. The Compensation Committee is
responsible for reviewing the performance and total compensation package for our
executive officers, including the President and Chief Executive Officer;
considering the modification of existing compensation and employee benefit
programs and the adoption of new plans; administering the terms and provisions
of any equity compensation or stock option plans (including our 1998 Long Term
Incentive Compensation Plan), 401(k), profit sharing plan and similar employee
benefit plans; and reviewing the compensation and benefits, if any, of
consultants and non-employee directors. The administration of option,
compensation or similar plans includes determining, subject to the respective
plan provisions, the individuals to whom awards are granted, the nature of the
awards to be granted, the number of awards to be granted, and the exercise
price, vesting schedule, term and all other conditions and terms of the awards
to be granted. We have no standing nominating committee.

         During the 1999 fiscal year, the Compensation Committee met three times
and acted by unanimous written consent on three occasions; and the Audit
Committee met once during the fiscal year ended December 31, 1999.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

         Section 16(a) of the Securities Exchange Act of 1934 requires our
executive officers, directors and persons who beneficially own more than 10% of
a registered class of our equity securities to file reports of ownership and
changes in ownership with the Securities and Exchange Commission.


                                       -5-
<PAGE>

Executive officers, directors and beneficial owners of more than 10% of our
Common Stock are required by regulations promulgated by the Securities and
Exchange Commission to furnish us with copies of all Section 16(a) forms that
they file. To our knowledge, based solely on a review of the copies of those
reports we received, the executive officers we hired in 1999 filed the requisite
initial reports of ownership on Form 3 on a timely basis after their appointment
by the Board as Vice Presidents; and our executive officers, directors and
greater than 10% stockholders satisfied all other Section 16(a) filing
requirements on a timely basis during the 1999 fiscal year.

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

         The following table sets forth the beneficial ownership of our Common
Stock as of December 31, 1999 by directors and executive officers, and any
person or group known to us to be the owner of more than five percent of our
Common Stock. Shares beneficially owned by the individuals below through family
partnerships or other entities they control are included in the number of shares
listed for that individual.

<TABLE>
<CAPTION>
                                                                          AMOUNT AND
                                NAME AND ADDRESS                     NATURE OF BENEFICIAL             PERCENT
TITLE OF CLASS                OF BENEFICIAL OWNER                         OWNERSHIP                  OF CLASS
- --------------                -------------------                    --------------------            --------
<S>                       <C>                                        <C>                            <C>
Common Stock              Timothy Scott, Ph.D. (President, Chief            4,507,667                   12.06
                          Executive Officer, Chief Financial
                          Officer, Treasurer)
                          7327 Oak Ridge Highway
                          Suite B
                          Knoxville, TN 37931

Common Stock              Eric A. Wachter, Ph.D. (Director, Vice            4,524,667                   12.10
                          President, Secretary)
                          7327 Oak Ridge Highway
                          Suite B
                          Knoxville, TN 37931

Common Stock              Craig Dees, Ph.D. (Director)                      4,521,667                   12.10
                          7327 Oak Ridge Highway
                          Suite B
                          Knoxville, TN 37931

Common Stock              Walter G. Fisher, Ph.D. (Director)                4,504,167                   12.05
                          7327 Oak Ridge Highway
                          Suite B
                          Knoxville, TN 37931
</TABLE>


                                       -6-
<PAGE>

<TABLE>
<CAPTION>
                                                                          AMOUNT AND
                                NAME AND ADDRESS                     NATURE OF BENEFICIAL             PERCENT
TITLE OF CLASS                OF BENEFICIAL OWNER                         OWNERSHIP                  OF CLASS
- --------------                -------------------                    --------------------            --------
<S>                      <C>                                                <C>                         <C>
Common Stock              Robert J. Weinstein, M.D. (Director)              3,455,421                    9.24
                          and
                          Lois Weinstein
                          875 N. Michigan Avenue
                          Suite 2930
                          Chicago, IL 60611-1901

Common Stock              Lester H. McKeever, Jr. (Director)                   36,000(1)                 0.09
                          819 South Wabash Avenue
                          Chicago, IL 60605

Common Stock              John Smolik (Director; President &                4,500,267                   12.04
                          CEO of Photogen, Inc.)
                          7327 Oak Ridge Highway
                          Suite B
                          Knoxville, TN 37931

Common Stock              Theodore Tannebaum (Director                      2,116,921                    5.66
                          Nominee)
                          875 N. Michigan Avenue
                          Suite 2930
                          Chicago, IL 60611-1901

Common Stock              Eugene Golub (Director Nominee)                      37,924(2)                 0.10
                          625 North Michigan Ave., Ste 2000
                          Chicago, IL 60611

Common Stock              Stuart P. Levine                                  3,291,621                    8.80
                          875 N. Michigan Avenue
                          Suite 2930
                          Chicago, IL 60611-1901

Common Stock              Gerald Wolf, Ph.D., M.D. (Vice                       75,000(3)                 0.20
                          President - Medical Director)
                          69 Milk Street, Suite 308
                          Westborough, MA 01581

            -             Vincent L. Fabiano (Director Nominee)                     0(4)                    0
                          3000 Horizon Drive
                          King of Prussia, PA 19406
</TABLE>


                                                        -7-
<PAGE>

<TABLE>
<CAPTION>
                                                                          AMOUNT AND
                                NAME AND ADDRESS                     NATURE OF BENEFICIAL             PERCENT
TITLE OF CLASS                OF BENEFICIAL OWNER                         OWNERSHIP                  OF CLASS
- --------------                -------------------                    --------------------            --------
<S>                      <C>                                              <C>                        <C>
            -             David Shaw, Ph.D. (Vice President -                      0                        0
                          Clinical Research and Technology
                          Development)
                          69 Milk Street, Suite 308
                          Westborough, MA 01581

            -             Jay Zimmerman, M.Ed. (Vice President                     0                        0
                          - Clinical Operations)
                          69 Milk Street, Suite 308
                          Westborough, MA 01581

Common Stock              All directors (including nominees) and          28,279,701                    75.65
                          executive officers as a group
                          (11 persons)
Common Stock              Parties to Voting Agreement(5)                  26,013,856                    69.59
                          (6 persons)
</TABLE>

- ---------------------
         (1) Includes 4,000 shares subject to vested options.

         (2) Includes 5,924 shares of our Series B Convertible Preferred Stock,
which are currently convertible into 5,924 shares of our Common Stock.

         (3) Includes 75,000 shares subject to vested options.

         (4) Mr. Fabiano is employed by an affiliate of Elan International
Services, Ltd., which owns 12,015 shares of our Series A Convertible
Exchangeable Preferred Stock. The Series A Preferred Stock is convertible into
approximately 567,548 shares of Common Stock under certain circumstances after
October 22, 2001. Mr. Fabiano disclaims beneficial ownership of the Series A
Preferred Stock.

         (5) The parties to the Voting Agreement may be deemed to be a "group"
within the meaning of Instruction 7 to Item 403 of Regulation S-B. The Voting
Agreement is described below.

         Drs. Wachter, Dees, Fisher, Scott and Mr. Smolik (the "Tennessee
Stockholders") and Dr. Weinstein (the "Chicago Stockholder") are parties to an
Amended and Restated Voting Agreement (the "Voting Agreement"). The Tennessee
Stockholders and Chicago Stockholder together currently own beneficially
26,013,856 shares, or approximately 69.59% of the Company's outstanding common
stock. The Voting Agreement currently provides that the Tennessee Stockholders
and Chicago Stockholder will vote their shares of common stock (i) in accordance
with the unanimous recommendation of the Board of Directors with respect to any
amendments to the Articles of Incorporation or Bylaws, (ii) to fix the number of
directors at six (we expect the Voting Agreement will be amended to provide for
seven directors), (iii) to elect to the Board of Directors four persons
nominated by holders of 80% of the shares of the Tennessee Stockholders and one
person nominated by holders of 80% of the shares of the Chicago Stockholder (and
to remove any such director at the request of the stockholders who nominated
him), and (iv) to fix the number of directors on the Board's Executive


                                       -8-
<PAGE>

Committee at three, two of whom will be selected by the Tennessee Stockholders
and one of whom will be selected by the Chicago Stockholder. The election of the
sixth director is not subject to the Voting Agreement; and we expect that the
future election of the seventh director will likewise not be subject to that
agreement. In addition, the Company agreed to comparable voting requirements and
restrictions with respect to its subsidiary Photogen, Inc. in its capacity as
sole stockholder of that corporation. The Voting Agreement has a term of 15
years, so long as the Tennessee Stockholders and Chicago Stockholder are the
beneficial owners of 20% or more of the outstanding Common Stock during that
period. The Tennessee Stockholders and Chicago Stockholder together control
management of the Company.

         Mr. Smolik, and Drs. Scott, Wachter, Dees, Fisher, who as of April 1,
2000 collectively hold approximately 22,558,435 shares of Common Stock, have
agreed not to sell or otherwise dispose of those shares for a period ending
August 2001, without the prior written consent of Theodore Tannebaum. Until
December 31, 2000, Mr. Tannebaum must consult with the placement agent for our
private placement of Series B Convertible Preferred Stock concerning any
proposed disposition by those five individuals.

         There are no arrangements currently known to us which may result in a
future change of control of the Company.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         No transaction between us and our directors, director nominees or
executive officers presently exists. However, we have received a commitment from
one of our principal stockholders and nominee for director, Theodore Tannebaum,
to make a $1 million credit facility available to us. If we use Mr. Tannebaum's
credit facility, borrowings will bear interest at 6% per year and interest only
will be paid annually, with the principal due in five years. The loan would be
secured by a lien on all of our assets.

EXECUTIVE COMPENSATION

         The following table sets forth compensation we paid to our executive
officers (the "Named Officers") for services rendered us in all capacities
during the year ended December 31, 1999.


                                         -9-
<PAGE>

<TABLE>
<CAPTION>
                                                          SUMMARY COMPENSATION TABLE

                                                     ANNUAL COMPENSATION                   LONG TERM COMPENSATION
                                                     -------------------                  ------------------------
                                                                                           AWARDS              PAYOUTS
                                                                        OTHER    --------------------------    -------       ALL
                                                                        ANNUAL   RESTRICTED      SECURITIES                 OTHER
                                                                        COMPEN-    STOCK         UNDERLYING     LTIP       COMPEN-
                                               SALARY       BONUS       SATION    AWARD(S)        OPTIONS      PAYOUTS      SATION
  NAME AND PRINCIPAL POSITION       YEAR        ($)           ($)         ($)       ($)              (#)         ($)         ($)
- -----------------------------------------------------------------------------------------------------------------------------------
<S>                               <C>        <C>         <C>        <C>          <C>           <C>             <C>         <C>
John Smolik,(1)                     1999      $125,000    $     0    $     0         0               0            0        $  0
  Former President,                 1998      $118,000          -          -         -               -            -           -
  Treasurer, CEO,                   1997      $ 85,000          -          -         -               -            -           -
  Chairman, and Chief
  Financial Officer

Timothy Scott, Ph.D.(1)             1999      $ 99,999    $     0    $     0         0               0            0        $  0
  Interim President,                1998      $ 97,500          -          -         -               -            -           -
  Treasurer, CEO and                1997      $ 85,000          -          -         -               -            -           -
  Chief Financial Officer

Eric A. Wachter, Ph.D.,(2)          1999      $ 99,999    $     0    $     0         0               0            0        $  0
  Director, Vice President,         1998      $ 97,500          -          -         -               -            -           -
  Secretary                         1997      $ 85,000          -          -         -               -            -           -

Gerald L. Wolf, Ph.D., M.D.(3)      1999      $190,000    $     0    $     0         0         750,000            0        $  0
  Vice President - Medical          1998         -
  Director                          1997         -

David D. Shaw, Ph.D.(3)             1999      $125,000    $     0    $     0         0         170,000            0        $  0
  Vice President  - Clinical        1998         -
  Research and Technology           1997         -
  Development

Jay Zimmerman, M.Ed.(3)             1999      $125,000    $     0    $     0         0         170,000            0        $  0
  Vice President  - Clinical        1998         -
  Operations                        1997         -
</TABLE>

         (1) Mr. Smolik resigned as President, Treasurer, CEO and Chief
Financial Officer of Photogen Technologies, Inc. on February 3, 2000. He
remains a Director of the Company and President and CEO of Photogen, Inc.
while the Company engages in a search for a new President and CEO. Timothy
Scott was appointed as Photogen Technologies, Inc.'s President, Treasurer,
CEO and Chief Financial Officer on February 3, 2000. Dr. Scott is also
employed as a Chief Operating Officer and a research scientist for Photogen,
Inc.

         (2) Two other Directors and Senior Scientists, Walter G. Fisher, Ph.D.
and Craig Dees, Ph.D., received the same compensation as Dr. Wachter during
1997, 1998 and 1999.

         (3) These individuals were hired at various times during 1999. The
compensation reported here is their contractual annual salary for a full year.


                                              -10-
<PAGE>

STOCK OPTIONS

         The following table contains information concerning the grant of stock
options under our 1998 Long Term Incentive Compensation Plan to the Named
Officers during our last fiscal year.

<TABLE>
<CAPTION>
                                                    1999 OPTION GRANTS

                                                           Individual Grants
                                    --------------------------------------------------------------
                                     Number of        % of Total
                                     Securities         Options
                                     Underlying       Granted to        Exercise
                                      Options          Employees         Price          Expiration
              Name                 Granted (#)(1)       In 1999          ($/Sh)            Date
             ------                --------------      ---------        --------        ----------
<S>                               <C>                <C>             <C>               <C>
John T. Smolik                              0               0                 0                 0
Timothy Scott, Ph.D.                        0               0                 0                 0
Eric A. Wachter, Ph.D.                      0               0                 0                 0
Gerald L. Wolf, Ph.D., M.D.           750,000            67.7            $9.375           7/23/09
David D. Shaw, Ph.D.                  150,000            13.5            $15.25          11/01/09
                                       20,000             1.8           $18.125          11/30/09
Jay Zimmerman, M.Ed.                  170,000            15.3           $18.125          11/30/09
</TABLE>
- ----------------------

(1)      The options were granted at an exercise price equal to the fair market
         value of the Company's Common Stock on the date of grant. A portion of
         the options become exercisable on various dates and other options
         become exercisable upon the occurrence of various performance criteria.


                                           -11-
<PAGE>

         The following table sets forth information about the Named Officers
concerning the exercise of options during the last fiscal year and unexercised
options held as of the end of the fiscal year.

<TABLE>
<CAPTION>
                                         1999 OPTION EXERCISES AND YEAR-END VALUES

                                 Shares                        Number of Securities              Value of Unexercised
                                Acquired                      Underlying Unexercised         In-the-Money Options at Year
                                   On          Value       Options at Year end 1999 (#)            End 1999 ($)(1)
                                Exercise      Realized    -------------------------------    -------------------------------
            NAME                   (#)           ($)      Exercisable       Unexercisable    Exercisable       Unexercisable
           ------                --------       -----     -------------------------------    -------------------------------
<S>                           <C>           <C>          <C>               <C>              <C>               <C>
John T. Smolik                      0             0               0              0               0                  0
Timothy Scott, Ph.D.                0             0               0              0               0                  0
Eric A. Wachter, Ph.D.              0             0               0              0               0                  0
Gerald L. Wolf, Ph.D., M.D.         0             0          75,000           675,000         684,375           6,159,375
David D. Shaw, Ph.D.                0             0               0           170,000            0               495,000
Jay Zimmerman, M.Ed.                0             0               0           170,000            0                63,750
</TABLE>
- ----------------------

(1)      For purposes of this table, the "value" of stock options was determined
         by the difference between the exercise price and $18.50, the closing
         price for Common Stock on the last business day of the fiscal year.
         Shares acquired on exercise of these options are not registered under
         the Securities Act of 1933 and are not freely saleable except in
         compliance with exemptions from registration, including the holding
         period and other requirements of Rule 144 thereunder. Consequently,
         the values set forth in the table are only theoretical values and may
         not accurately represent actual market value.

         We have Employment Agreements in place with Drs. Scott, Wachter,
Fisher, Dees, Wolf and Shaw and with Messrs. Smolik and Zimmerman. Each
Employment Agreement has a term expiring between 2002 and 2003 (subject to
earlier termination for cause) and provides that while the individual is
employed by us and for a period of one or two years after termination he will
not engage in activities which compete with our business. The Employment
Agreements also require the employee to disclose to the Board of Directors
all inventions or other intellectual property discovered or made by the
employee during his employment and twelve months thereafter, if those
inventions are related to or useful in our business, or result from duties
assigned to that individual or from the use of any of our assets or
facilities. Drs. Scott, Wachter, Fisher, Dees, Wolf, Shaw and Messrs. Smolik
and Zimmerman each receive typical health, life and disability insurance
benefits that are available to our other salaried employees. These
individuals are also eligible to defer a portion of their salary through our
401(k) plan, but the Company does not match or make any contributions to the
401(k) plan nor does the Company maintain a pension plan.

         Officers generally serve at the discretion of the Board of Directors.
We have no compensatory plans or arrangements resulting from the resignation,
retirement or any other termination of an executive officer's employment with us
or from a change in control.

         Our directors receive no specified compensation for serving as
directors, and have no standard arrangements providing for such compensation. In
August 1998, Mr. McKeever received an award of non-qualified options under our
1998 Long Term Incentive Compensation Plan to acquire 20,000 shares of Common
Stock at an exercise price of $13.25. These options vest over five years from
the date of grant.


                                -12-
<PAGE>

                                   PROPOSAL 2

       APPROVAL OF AN AMENDMENT TO THE COMPANY'S ARTICLES OF INCORPORATION

         On February 3, 2000, the Board of Directors unanimously approved
amending the Company's Articles of Incorporation (subject to stockholder
approval at the Annual Meeting) to increase the size of the Board of Directors
from six to seven directors and to provide that all vacancies on the Board of
Directors shall be filled as provided in the Company's Bylaws. The Articles of
Incorporation currently provide that there will be six directors on the
Company's Board of Directors and vacancies will be filled by vote of the
stockholders. As amended, Article Fifth would read as follows:

                  FIFTH: (a) The governing board of the Corporation shall be
         styled as a "Board of Directors," and any member of said Board shall be
         styled as a "director."

                  (b)      The authorized number of members constituting the
         Board of Directors of the Corporation is seven (7).

                  (c)      All vacancies on the Board of Directors, including
         those caused by an increase in the number of directors, shall be
         filled in the manner provided by the Bylaws.

         After the Annual Meeting, the Board of Directors plans to amend the
Company's Bylaws to provide that vacancies on the Board (resulting from an
increase in the size of the Board or a director's resignation or removal)
arising between regular elections for directors will be filled by a majority of
the remaining directors then in office. These proposed changes to the Articles
of Incorporation and Bylaws are part of our plan to create a more diverse and
flexible management structure. Increasing the size of the Board to include seven
members will enable us to utilize the insight and expertise of an additional
director. We also believe that amending the Articles of Incorporation to enable
the directors to fill vacancies on the Board existing between regular elections
should enhance our flexibility by enabling us to appoint a director without
having to call a special meeting of the stockholders. We presently expect the
seventh Board seat to be filled by our President and Chief Executive Officer
when chosen.

         In keeping with our desire for greater flexibility, the Board also
intends to amend the Company's Bylaws to eliminate the requirement of unanimous
Board approval for certain material transactions. The unanimous approval
requirement will be changed to a requirement that five of seven directors
approve certain matters and transactions, and that a majority approve certain
other matters. (We expect to make comparable changes to the Charter and Bylaws
of Photogen, Inc. after the Annual Meeting.)

         THE BOARD RECOMMENDS A VOTE FOR APPROVAL OF THE AMENDMENT TO THE
COMPANY'S ARTICLES OF INCORPORATION INCREASING THE SIZE OF THE BOARD OF
DIRECTORS FROM SIX TO SEVEN DIRECTORS AND PROVIDING THAT ALL VACANCIES OF THE
BOARD OF DIRECTORS SHALL BE FILLED AS PROVIDED FOR IN THE COMPANY'S BYLAWS.


                                      -13-
<PAGE>

                                   PROPOSAL 3

                     APPROVAL OF THE 2000 STOCK OPTION PLAN

         The Board of Directors believes that it is in the Company's best
interests to continue the practice of making stock options available to those
employees responsible for significant contributions to our business. The Board
believes that the equity stake in our development and success afforded by stock
options provides key employees with an incentive to continue to energetically
apply their talents to our business.

         In 1998, we established the 1998 Long Term Incentive Compensation Plan
(the "1998 Plan") enabling our Compensation Committee to award options to
purchase up to 2 million shares of Common Stock. Since 1998, the Compensation
Committee has totaling 1,117,500 shares. We believe this option program has been
an important component in our ability to attract talented professionals. There
are now only 882,500 shares available under the 1998 Plan.

         As a result, on February 3, 2000, the Board of Directors unanimously
approved the 2000 Long Term Incentive Compensation Plan (the "2000 Plan") and
directed that it be submitted for consideration and action at the Annual
Meeting. A majority of the shares voted at the annual meeting must vote in favor
of the 2000 Plan for it to be adopted. If the 2000 Plan is approved by the
stockholders, options will not be granted under the 2000 Plan until all options
have been granted under the existing 1998 Long Term Incentive Compensation Plan.

         THE BOARD RECOMMENDS A VOTE FOR APPROVAL OF THE 2000 LONG TERM
INCENTIVE COMPENSATION PLAN.

         The following is a brief but not comprehensive summary of the 2000 Long
Term Incentive Compensation Plan ("2000 Plan") which in most material respects
is nearly identical to the 1998 Long Term Incentive Compensation Plan. The
complete text of the 2000 Plan is attached as Annex B and you should refer to
that Annex for a complete statement of the Plan's provisions.

         INTRODUCTION. The 2000 Plan is intended to advance our interests by
providing key employees and certain consultants with additional incentives to
promote the success of our business, to increase their proprietary interest in
our success and to encourage them to remain in our employ. The Board and its
Compensation Committee believe that the 2000 Plan is a necessary tool to help us
compete effectively with other enterprises for the services of new employees and
to retain key employees and directors, all as may be required for the future
development of our business. We cannot determine at this time how many potential
consultants or employees will be eligible for receipt of awards under the 2000
Plan. The Board presently contemplates that current employee directors will not
be considered for awards under the 2000 Plan during our 2000 fiscal year.

         Each director, each nominee for director and each officer and employee
of the Company has, by reason of being eligible to receive awards under the 2000
Plan, an interest in seeing that the 2000 Plan is adopted by the stockholders.


                                        -14-
<PAGE>

         NATURE OF AWARDS TO BE GRANTED PURSUANT TO THE 2000 PLAN. The 2000 Plan
provides for the grant of options intended to qualify as "incentive stock
options" ("ISOs") under Section 422(b) of the Internal Revenue Code of 1986 (the
"Code") and non-qualified stock options ("NQSOs") and Restricted Stock Awards.
The 2000 Plan also permits awards of restricted stock.

         COMMON STOCK SUBJECT TO THE 2000 PLAN. The aggregate number of shares
of Common Stock covered by the 2000 Plan is 2,000,000 shares.

         Shares issued upon exercise of options or awards of Restricted Stock
under the 2000 Plan may be either authorized but unissued shares or shares
re-acquired by the Company. If, on or prior to the termination of the 2000 Plan,
an award expires or is terminated for any reason without having been exercised
or vested in full, the unpurchased or unvested shares will again become
available for the grant of awards under the 2000 Plan.

         The purchase price of the shares of Common Stock covered by each NQSO
will be determined by the Compensation Committee and will be at least the par
value of the shares. ISOs will have an exercise price of at least 100% of the
fair market value of the Common Stock at the time the option is granted,
determined by reference to the closing sale price at which the Common Stock
trades on the principal securities exchange on which the shares are traded.

         No option granted to any person who, at the time of such grant, owns
(taking into account the attribution rules of Section 424(d) of the Code) stock
possessing more than 10% of the total combined voting power of all classes of
our stock or of the stock of any of our corporate subsidiaries, may be
designated as an ISO unless at the time of such grant the purchase price of the
shares of Common Stock covered by such option is at least 110% of the fair
market value, but in no event less than the par value, of such shares. The
aggregate fair market value (determined at the time each ISO is granted) of the
shares of Common Stock with respect to which ISOs issued to any one person are
exercisable for the first time during any calendar year may not exceed $100,000.

         Awards of Restricted Stock under the 2000 Plan will be made at the
discretion of the Compensation Committee and will consist of shares of Common
Stock granted to a participant and covered by a Restricted Stock award
agreement. At the time of an award, a participant will have the benefits of
ownership in respect of such shares, including the right to vote such shares and
receive dividends thereon and other distributions, subject to the restrictions
in the 2000 Plan and in the Restricted Stock award agreement. The shares will be
legended and, at our option, may be held in escrow and may not be sold,
transferred or disposed of until such restrictions have lapsed. Each award may
be subject to a lapsing formula pursuant to which the restrictions on
transferability lapse over a particular time period. The Compensation Committee
has broad discretion as to the specific terms and conditions of each award,
including applicable rights upon certain terminations of employment.

         ADMINISTRATION OF THE 2000 PLAN. The 2000 Plan will be administered by
the Compensation Committee. The Compensation Committee has full and exclusive
authority to, among other things, determine the grant of awards under the 2000
Plan. Dr. Weinstein and Mr. McKeever currently serve as the members of the
Compensation Committee.

         PURCHASE OF COMMON STOCK UNDER THE 2000 PLAN. Each award granted under
the 2000 Plan will be granted pursuant to and subject to the terms and
conditions of an award agreement (an "Award


                                      -15-
<PAGE>

Agreement") to be entered into between the Company and the awardholder at the
time of the grant. Any Award Agreement will incorporate by reference all of the
terms and provisions of the 2000 Plan as in effect at the time of grant and may
contain other terms and provisions as may be approved by the Compensation
Committee.

         The expiration date of an award granted under the 2000 Plan will be
determined by the Compensation Committee at the time of grant. Each award will
become exercisable or vested in whole, in part or in installments, at the time
or times as the Compensation Committee may prescribe and specify in the Award
Agreement.

         In the event of a "Change in Control" (defined in the 2000 Plan) of the
Company, awards granted under the 2000 Plan which, by their terms, vest or are
exercisable in installments, will become immediately exercisable or vested in
full. These provisions of the 2000 Plan may have some deterrent effect on
certain mergers, tender offers or other takeover attempts, thereby having some
potential adverse effect on the market price of our Common Stock.

         The exercise price for options granted under the 2000 Plan may be paid
in any of the following ways, which may be combined for any given exercise: (i)
the exercise price may be paid in cash or its equivalent; (ii) the exercise
price may be paid by tendering previously acquired shares of Common Stock having
a fair market value equal to the aggregate exercise price for the options being
exercised; or (iii) subject to applicable requirements of the Exchange Act, the
optionholder may deliver with his or her exercise notice irrevocable
instructions to a broker to promptly deliver to us an amount of sale or loan
proceeds sufficient to pay the exercise price.

         Awards granted under the 2000 Plan are assignable or transferable by
will or pursuant to the laws of descent and distribution or as otherwise
specifically permitted by the Award Agreement or by the Compensation Committee,
and options will be exercisable during the awardholder's lifetime by the
awardholder himself or herself or any permitted transferee. No holder of any
option will have any rights to dividends or other rights of a stockholder with
respect to shares subject to an option before exercising the option.

         TERMINATION OF EMPLOYMENT, DEATH OR DISABILITY OF OPTIONHOLDER. Each
option, to the extent it has not been previously exercised, will terminate upon
the earliest to occur of: (i) the expiration of the option period set forth in
the Award Agreement; (ii) for ISOs, the expiration of three months following the
Participant's retirement (following the Participant's retirement, NQSOs will
terminate upon the expiration of the option period set forth in the Award
Agreement); (iii) the expiration of 12 months following the Participant's death
or disability; (iv) immediately upon termination for cause; (v) the expiration
of 90 days following the Participant's termination of employment for any reason
other than cause, Change in Control, death, disability, or retirement; or (vi)
at such other time and on such conditions provided for in the Award Agreement.
Upon a termination of employment related to a Change in Control, options will be
treated in the manner set forth in the Change of Control provisions.

         Upon a Participant's death, disability, or retirement, all Restricted
Stock will vest immediately. Each Award Agreement will set forth the extent to
which the Participant will have the right to retain unvested restricted shares
following termination of the Participant's employment with the Company in all
other circumstances. Such provisions will be determined in the sole discretion
of the Compensation Committee, will be included in the Award Agreement entered
into with each Participant, need not be


                                      -16-
<PAGE>

uniform among all shares of Restricted Stock issued pursuant to the 2000 Plan,
and may reflect distinctions based on the reasons for termination of employment.

         EXPIRATION, TERMINATION AND AMENDMENT OF THE 2000 PLAN. The 2000 Plan
may at any time be terminated, modified, altered, suspended or amended by the
Board of Directors or the Compensation Committee. The Board of Directors or the
Compensation Committee may, insofar as permitted by law, from time to time with
respect to any shares of Common Stock at the time not subject to options or
other awards, suspend or discontinue the 2000 Plan or revise or amend it in any
respect whatsoever, except that, without approval of the stockholders of the
Company, no such revision or amendment may increase the number of shares
available for grants of ISOs under the 2000 Plan or alter the class of
participants in the 2000 Plan. Subject to the provisions described above, the
Board of Directors or the Compensation Committee will have the power to amend
the 2000 Plan and any outstanding awards granted thereunder in such respects as
the Board of Directors or the Compensation Committee may, in its sole
discretion, deem advisable in order to incorporate in the 2000 Plan or any such
award any new provision or change designed to comply with or take advantage of
requirements or provisions of the Code or other statute, or rules or regulations
of the Internal Revenue Service or other federal or state governmental agency
enacted or promulgated after the adoption of the 2000 Plan.

         FEDERAL TAX CONSEQUENCES. We believe that the following generally
summarizes the federal income tax consequences of awards under the Plan for
participants and the Company. A participant will not be deemed to have received
any income subject to tax at the time a stock option (including an ISO) or
Restricted Stock award that is subject to conditions, restrictions or
contingencies is awarded, nor will we be entitled to a tax deduction at that
time. When a stock option (other than an ISO) is exercised, the participant will
be deemed to have received an amount of ordinary income equal to the excess of
the fair market value of the shares purchased over the exercise price. The
income tax consequences of Restricted Stock Awards will depend on how the awards
are structured, but generally, a participant will be deemed to have ordinary
income at the time a Restricted Stock Award is distributed to him free of all
conditions, restrictions and contingencies. In each case, the Company will be
allowed a tax deduction in the year and in an amount equal to the amount of
ordinary income that the participant is deemed to have received. The extent of
the deduction for certain highly compensated employees may be limited to $1
million annually for performance based awards under Section 162(m) of the
Internal Revenue Code.

         If an ISO is exercised by a participant who satisfies certain
employment requirements at the time of exercise, the participant will not be
deemed to have received any income subject to tax at such time, although the
excess of the fair market value of the common stock so acquired on the date of
exercise over the exercise price will be an item of tax preference for purposes
of the alternative minimum tax. Section 422 of the Code provides that if the
Common Stock is held at least one year after the exercise date and two years
after the date of grant, the participant will realize a long-term capital gain
or loss upon a subsequent sale, measured as the difference between the exercise
price and the sales price. If Common Stock acquired upon the exercise of an ISO
is not held for one year, a "disqualifying disposition" results, at which time,
the participant is deemed to have received an amount of ordinary income equal to
the lesser of (a) the excess of the fair market value of the Common Stock on the
date of exercise over the exercise price or (b) the excess of the amount
realized on the disposition of the shares over the exercise price. If the amount
realized on the "disqualifying disposition" of the Common Stock exceeds the fair
market value on the date of exercise, the gain on the excess of the ordinary
income portion will be treated as a capital gain. Any loss on the disposition of
Common Stock acquired through the exercise of an ISO is a capital loss. No
income tax deduction will be allowed to us with respect to


                                      -17-
<PAGE>

shares of Common Stock purchased by a participant through the exercise of an
ISO, provided there is no "disqualifying disposition" as described above. In the
event of a "disqualifying disposition", we are entitled to a tax deduction equal
to the amount of ordinary income recognized by the participant.

         NEW PLAN BENEFITS. No awards have been granted under the 2000 Plan. The
Board of Directors contemplates that no Awards under the 2000 Plan will be given
to current employee directors during the fiscal year ending December 31, 2000 in
view of their existing substantial holdings in the Company. Because the 2000
Plan gives broad discretion with respect to the Awards to the Compensation
Committee we cannot determine the amount of the Awards that would have been
granted to the eligible officers, directors and key employees during the fiscal
year ending December 31, 1999 at this time. During the 2000 fiscal year the
Company may consider hiring additional employees and/or consultants who may
become eligible for receipt of Awards under the 2000 Plan. At this point,
however, we cannot provide information as to the amount of the Awards, if any,
which would be granted to under the 2000 Plan.

                                   PROPOSAL 4

                         RATIFICATION OF APPOINTMENT OF
                    INDEPENDENT CERTIFIED PUBLIC ACCOUNTANTS

         BDO Seidman, LLP, Chicago, Illinois, has served as independent
certified public accountants for us and our predecessors and subsidiaries since
1995, including the 1999 fiscal year. The Board of Directors has approved
retaining that firm for the 2000 fiscal year. We expect that a representative of
BDO Seidman, LLP will be present at the Annual Meeting and will be available to
answer appropriate questions from stockholders.

         Proposal Number 4 at the Annual Meeting is to ratify the selection of
BDO Seidman, LLP as our independent certified public accountants for 2000.
Although the appointment of independent certified public accountants is not
required to be approved by the stockholders, the Board of Directors has decided
to ascertain the position of the stockholders on that appointment. The Board
will reconsider the appointment of BDO Seidman, LLP if it is not ratified.

         THE BOARD RECOMMENDS A VOTE FOR THE RATIFICATION OF BDO SEIDMAN, LLP AS
THE COMPANY'S INDEPENDENT CERTIFIED PUBLIC ACCOUNTS FOR 2000.

                                  OTHER MATTERS

         If any other matters are properly presented at the Annual Meeting,
including a motion to adjourn, the persons named as Proxies will have discretion
to vote on those matters according to their best judgment to the same extent as
a person delivering a Proxy would be entitled to vote. At the date this Proxy
Statement went to press, we did not anticipate that any other matters would be
raised at the Annual Meeting.


                                        -18-
<PAGE>

                                     ANNEX A

                           PHOTOGEN TECHNOLOGIES, INC.

                   2000 LONG TERM INCENTIVE COMPENSATION PLAN

1.       ESTABLISHMENT, OBJECTIVES AND DURATION.

         a.       ESTABLISHMENT OF THE PLAN. Photogen Technologies, Inc. hereby
                  establishes an incentive compensation plan to be known as the
                  "Photogen Technologies, Inc. 2000 Long Term Incentive
                  Compensation Plan" (the "Plan"), as set forth in this
                  document. The Plan permits the grant of Incentive Stock
                  Options, Nonqualified Stock Options and Restricted Stock.

         b.       OBJECTIVES OF THE PLAN. The objectives of the Plan are to
                  optimize the profitability and growth of the Company through
                  the use of incentives which are consistent with the Company's
                  objectives and which link the interests of Participants to
                  those of the Company's stockholders; to provide Participants
                  with an incentive for excellence in individual performance;
                  and to promote teamwork among Participants. The Plan is
                  further intended to provide flexibility to the Company in its
                  ability to motivate, attract, and retain the services of
                  Participants who make significant contributions to the
                  Company's success and to allow Participants to share in the
                  success of the Company.

         c.       DURATION OF THE PLAN. The Plan shall become effective as of
                  the date it is approved by the stockholders of Photogen
                  Technologies, Inc. (the "Effective Date"). The Plan shall
                  remain in effect, subject to the right of the Board of
                  Directors or the Committee to amend or terminate the Plan at
                  any time pursuant to Section 11 hereof, until all Shares
                  subject to it shall have been purchased or acquired according
                  to the Plan's provisions. However, in no event may an
                  Incentive Stock Option be granted under the Plan on or after
                  May 17, 2010.

2.       DEFINITIONS.

Whenever used in the Plan, the following terms shall have the meanings set forth
below:

         a.       "AFFILIATE" means a "parent corporation" or "subsidiary
                  corporation" as defined in Section 424 of the Code.

         b.       "AWARD" means, individually or collectively, a grant under
                  this Plan of Incentive Stock Options, Nonqualified Stock
                  Options or Restricted Stock.

         c.       "AWARD AGREEMENT" means an agreement entered into by the
                  Company and each Participant setting forth the terms and
                  provisions applicable to Awards granted under this Plan.

         d.       "BENEFICIAL OWNER" or "BENEFICIAL OWNERSHIP" shall have the
                  meaning ascribed to such term in Rule 13d-3 of the General
                  Rules and Regulations under the Exchange Act.

<PAGE>

         e.       "BOARD" or "BOARD OF DIRECTORS" means the Board of Directors
                  of the Company.

         f.       "CAUSE" shall be determined by the Committee, exercising good
                  faith and reasonable judgment, and shall mean the occurrence
                  of any one or more of the following:

                  i.       The willful and continued failure by the Participant
                           to substantially perform his duties (other than any
                           such failure resulting from the Participant's
                           Disability) after a written demand for substantial
                           performance is delivered by the Committee to the
                           Participant that identifies in reasonable detail the
                           manner in which the Committee believes that the
                           Participant has not substantially performed his
                           duties, and the Participant has failed to remedy the
                           situation within 30 calendar days of receiving such
                           notice; or

                  ii.      The Participant's conviction for committing an act of
                           fraud, embezzlement, theft or another act
                           constituting a felony; or

                  iii.     Any breach by a Participant of any written agreement
                           with the Company, including any agreement concerning
                           a Participant's employment, non-competition or
                           confidentiality of Company proprietary information;
                           or

                  iv.      The willful engaging by the Participant in gross
                           misconduct materially and demonstrably injurious to
                           the Company, as determined by the Committee.

         g.       "CHANGE IN CONTROL" of the Company shall be deemed to have
                  occurred as of the first day that any one or more of the
                  following conditions shall have been satisfied:

                  i.       The acquisition by any Person of Beneficial Ownership
                           of 50% or more of either (i) the then outstanding
                           shares of Common Stock of the Company, or (ii) the
                           combined voting power of the outstanding voting
                           securities of the Company entitled to vote generally
                           in the election of Directors; provided, however, that
                           for purposes of this subsection, the following
                           transactions shall not constitute a Change of
                           Control: (A) any acquisition directly from the
                           Company through a public offering of shares of Common
                           Stock of the Company, (B) any acquisition by the
                           Company, (C) any acquisition by any employee benefit
                           plan (or related trust) sponsored or maintained by
                           the Company or any corporation controlled by the
                           Company, or (D) any acquisition by any corporation
                           pursuant to a transaction which complies with clauses
                           (i), (ii) and (iii) of subsection (C) below;

                  ii.      The cessation, for any reason, of the individuals who
                           constitute the Company's Board of Directors as of the
                           date hereof ("Incumbent Board") to constitute at
                           least a majority of the Company's Board of Directors;
                           provided, however, that any individual becoming a
                           Director following the date hereof whose election, or
                           nomination for election by the Company's
                           stockholders, was approved by a vote of at least a
                           majority of the Directors then comprising the
                           Incumbent Board shall be considered as though such
                           individual was a member of the Incumbent Board, but
                           excluding, for this purpose, any such individual
                           whose initial assumption of


                                      -2-
<PAGE>

                           office occurs because of an actual or threatened
                           election contest with respect to the election or
                           removal of Directors or other actual or threatened
                           solicitation of proxies or consents by or on behalf
                           of a Person other than the Company's Board of
                           Directors;

                  iii.     The consummation of a reorganization, merger or
                           consolidation or sale or other disposition of all or
                           substantially all of the assets of the Company
                           ("Business Combination") unless, following such
                           Business Combination, (i) all or substantially all of
                           the individuals and entities who were the Beneficial
                           Owners, respectively, of the outstanding shares of
                           Common Stock of the Company and the outstanding
                           voting securities of the Company immediately before
                           such Business Combination beneficially own, directly
                           or indirectly, more than 50% of, respectively, the
                           then outstanding shares of Common Stock and the
                           combined voting power of the then outstanding voting
                           securities entitled to vote generally in the election
                           of Directors, as the case may be, of the Company
                           resulting from such Business Combination (including,
                           without limitation, a corporation which as a result
                           of such transaction owns the Company or all or
                           substantially all of the Company's assets either
                           directly or through one or more subsidiaries) in
                           substantially the same proportions as their ownership
                           immediately before such Business Combination of the
                           outstanding shares of Common Stock and the
                           outstanding voting securities of the Company, as the
                           case may be; (ii) no party (excluding any corporation
                           resulting from such Business Combination or any
                           employee benefit plan (or related trust) of the
                           Company or such corporation resulting from such
                           Business Combination) beneficially owns, directly or
                           indirectly, 50%; or more of, respectively, the then
                           outstanding shares of common stock of the corporation
                           resulting from such Business Combination or the
                           combined voting power of the then outstanding voting
                           securities of such corporation except to the extent
                           that such ownership existed before the Business
                           Combination; and (iii) at least a majority of the
                           members of the board of directors of the corporation
                           resulting from such Business Combination were members
                           of the Company's Board of Directors at the time of
                           the execution of the initial agreement, or of the
                           action of the Company's Board of Directors, providing
                           for such Business Combination; or

                  iv.      The approval by the stockholders of the Company of a
                           complete liquidation or dissolution of the Company.

         h.       "CODE" means the Internal Revenue Code of 1986, as amended
                  from time to time.

         i.       "COMMITTEE" means the Compensation Committee of the Board, as
                  specified in Section 3 herein, or such other Committee
                  appointed by the Board to administer the Plan with respect to
                  grants of Awards.

         j.       "COMPANY" means Photogen Technologies, Inc., a Nevada
                  corporation, and also means any corporation of which a
                  majority of the voting capital stock is owned directly or
                  indirectly by Photogen Technologies Inc. or by any of its
                  Subsidiaries, and any other


                                       -3-
<PAGE>

                  corporation designated by the Committee as being a Company
                  hereunder (but only during the period of such ownership or
                  designation).

         k.       "DIRECTOR" means any individual who is a member of the Board
                  of Directors of the Company.

         l.       "DISABILITY", as applied to a Participant, means that the
                  Participant (a) has established to the satisfaction of the
                  Committee that the Participant is unable to engage in any
                  substantial gainful activity by reason of any medically
                  determinable physical or mental impairment which can be
                  expected to last for a continuous period of not less than 12
                  months (all within the meaning of Section 22(e)(3) of the
                  Code), and (b) has satisfied any requirement imposed by the
                  Committee in regard to evidence of such disability.

         m.       "ELIGIBLE PERSON" shall mean all Employees, Directors or
                  consultants of the Company or any Affiliate; provided,
                  however, that no Award may be granted to anyone who is not an
                  "employee" as that term is defined in General Instruction
                  A.(1)(a) of Form S-8, as such definition may be amended from
                  time to time, without first receiving advice and guidance from
                  the Company's outside counsel as to the effect of such grant.

         n.       "EMPLOYEE" means any officer or employee of the Company.

         o.       "EXCHANGE ACT" means the Securities Exchange Act of 1934, as
                  amended from time to time, or any successor act thereto.

         p.       "FAIR MARKET VALUE" Except as otherwise determined by the
                  Committee, the "Fair Market Value" of a share of Common Stock
                  as of any date shall be equal to the closing sale price of a
                  share of Common Stock as reported on The National Association
                  of Securities Dealers' New York Stock Exchange Composite
                  Reporting Tape (or if the Common Stock is not traded on The
                  New York Stock Exchange, the closing sale price on the
                  exchange on which it is traded or as reported by an applicable
                  automated quotation system, including the over-the-counter
                  bulletin board) (the "Composite Tape"), on the applicable date
                  or, if no sales of Common Stock are reported on such date, the
                  closing sale price of a share of Common Stock on the date the
                  Common Stock was last reported on the Composite Tape (or such
                  other exchange or automated quotation system, if applicable)
                  as of the date specified by the Committee (and if no date is
                  specified, then on the date of the meeting of the Committee at
                  which the award was granted).

         q.       "IMMEDIATE FAMILY MEMBERS" means the spouse, children and
                  grandchildren of a Participant.

         r.       "INCENTIVE STOCK OPTION" or "ISO" means an option to purchase
                  Shares granted under Section 6 herein and which is designated
                  as an Incentive Stock Option and which is intended to meet the
                  requirements of Code Section 422.

         s.       "INSIDER" shall mean an individual who is, on the relevant
                  date, a Director, a 10% Beneficial Owner of any class of the
                  Company's equity securities that is registered


                                       -4-
<PAGE>

                  pursuant to Section 12 of the Exchange Act or an officer of
                  the Company, as defined under Section 16 of the Exchange Act
                  and as determined by the Board of Directors from time to time.

         t.       "NONEMPLOYEE DIRECTOR" means an individual who is a member of
                  the Board of Directors of the Company but who is not an
                  Employee of the Company.

         u.       "NONQUALIFIED STOCK OPTION" or "NQSO" means an option to
                  purchase Shares granted under Section 6 herein and which is
                  not intended to meet the requirements of Code Section 422.

         v.       "OPTION" means an Incentive Stock Option or a Nonqualified
                  Stock Option, as described in Section 6 herein.

         w.       "OPTION PRICE" means the price at which a Share may be
                  purchased by a Participant pursuant to an Option.

         x.       "PARTICIPANT" means an Eligible Person who has outstanding an
                  Award granted under the Plan.

         y.       "PERIOD OF RESTRICTION" means the period during which the
                  transfer of Shares of Restricted Stock is limited in some way
                  (based on the passage of time, the achievement of performance
                  objectives, or upon the occurrence of other events as
                  determined by the Committee, at its discretion), and the
                  Shares of Restricted Stock are subject to a substantial risk
                  of forfeiture, as provided in Section 7 herein.

         z.       "PERSON" shall have the meaning ascribed to such term in
                  Section 3(a)(9) of the Exchange Act and used in Sections 13(d)
                  and 14(d) thereof, including a "group" as defined in Section
                  13(d) thereof.

         aa.      "RESTRICTED STOCK" means an Award granted to a Participant
                  pursuant to Section 7 herein.

         bb.      "RETIREMENT" as applied to a Participant, means the
                  Participant's termination of employment in a manner which
                  qualifies the Participant to receive immediately payable
                  retirement benefits under any applicable retirement plan
                  maintained by the Company (the "Retirement Plan"), under the
                  successor or replacement of such Retirement Plan if it is then
                  no longer in effect, or under any other retirement plan
                  maintained or adopted by the Company which is determined by
                  the Committee to be the functional equivalent of such
                  Retirement Plan; or, with respect to a Participant who may not
                  or has not participated in a retirement plan or if there is no
                  such retirement plan maintained by the Company or an
                  Affiliate, "Retirement" shall have the meaning determined by
                  the Committee from time to time.

         cc.      "SHARES" means Common Stock of Photogen Technologies, Inc.,
                  par value $.001 per share.


                                       -5-
<PAGE>

         dd.      "SUBSIDIARY" means any corporation, partnership, joint venture
                  or other entity in which the Company has a majority voting
                  interest.

3.       ADMINISTRATION.

         a.       THE COMMITTEE. The Plan shall be administered by the
                  Committee, or by any other committee appointed by the Board,
                  which Committee shall consist solely of two or more
                  "Nonemployee Directors" within the meaning of Rule 16b-3 under
                  the Exchange Act, or any successor provision. The members of
                  the Committee shall be appointed from time to time by, and
                  shall serve at the discretion of, the Board of Directors.

         b.       AUTHORITY OF THE COMMITTEE. Except as limited by law and
                  subject to the provisions herein, the Committee shall have
                  full power in its discretion to select Eligible Persons who
                  shall participate in the Plan; determine the sizes and types
                  of Awards; determine the terms and conditions of Awards
                  (including vesting periods and restrictions); prescribe the
                  form of, construe and interpret any agreement or instrument
                  entered into under the Plan as they apply to Participants;
                  construe and interpret the terms and conditions of this Plan;
                  establish, amend, or waive rules and regulations for the
                  Plan's administration as they apply to Participants; alter,
                  amend, suspend or terminate the Plan in whole or in part; and
                  (subject to the provisions of Section 11 herein) amend the
                  terms and conditions of any outstanding Award to the extent
                  such terms and conditions are within the discretion of the
                  Committee as provided in the Plan. Further, the Committee
                  shall make all other determinations which may be necessary or
                  advisable for the administration of the Plan. As permitted by
                  law, the Committee may delegate its authority as identified
                  herein.

         c.       DECISIONS BINDING. All determinations and decisions made by
                  the Committee pursuant to the provisions of the Plan and all
                  related orders and resolutions of the Board shall be final,
                  conclusive and binding on all persons, including the Company,
                  its stockholders, Employees, Participants and their estates
                  and beneficiaries.

         d.       COSTS OF PLAN. The costs and expenses incurred in the
                  operation and administration of the Plan shall be borne by the
                  Company.

         e.       INDEMNIFICATION. Each person who is or shall have been a
                  member of the Committee shall be indemnified and held harmless
                  by the Company against and from any loss, cost, liability, or
                  expense that may be imposed upon or reasonably incurred by him
                  in connection with or resulting from any claim, action, suit,
                  or proceeding to which he may be a party or in which he may be
                  involved by reason of any action taken or failure to act under
                  the Plan and against and from any and all amounts paid by him
                  in settlement thereof, to the fullest extent permitted by the
                  Nevada General Corporation Law. The foregoing right of
                  indemnification shall not be exclusive of any other rights of
                  indemnification to which such persons may be entitled under
                  the Company's Sections of Incorporation or Bylaws, as a matter
                  of law, or otherwise, or any power that the Company may have
                  to indemnify them or hold them harmless. In addition, a member
                  of the Committee, in the performance of any act (or in
                  refraining from taking any action) in connection with the
                  Plan, shall not be liable to the Company, its stockholders,


                                       -6-
<PAGE>

                  Employees, Participants or any person when relying in good
                  faith upon the records of the Company or upon such information
                  or statements presented to the Company by any of its officers,
                  employees or other persons as to matters the member reasonably
                  believes are within such other person's professional or expert
                  competence and who has been selected with reasonable care by
                  or on behalf of the Company.

4.       SHARES SUBJECT TO THE PLAN AND MAXIMUM AWARDS.

         a.       NUMBER OF SHARES AVAILABLE FOR GRANTS. Subject to adjustment
                  as provided in Section 4.2 herein, the number of Shares hereby
                  reserved for issuance to Participants under the Plan shall be
                  2,000,000. Shares issued upon exercise of Options or Awards of
                  Restricted Stock under the Plan may be either authorized but
                  unissued Shares or Shares re-acquired by the Company. If, on
                  or prior to the termination of the Plan, an Award granted
                  thereunder expires or is terminated for any reason without
                  having been exercised or vested in full, the unpurchased or
                  unvested Shares covered thereby will again become available
                  for the grant of Awards under the Plan. Shares of Common Stock
                  covered by Options surrendered in connection with the exercise
                  of other Options shall not be deemed to have been exercised
                  and shall again become available for the grant of awards under
                  the Plan.

         b.       ADJUSTMENTS IN AUTHORIZED SHARES. In the event of any change
                  in corporate capitalization, such as a stock split, or a
                  corporate transaction, such as any merger, consolidation,
                  separation, including a spin-off, or other distribution of
                  stock or property of the Company, any reorganization (whether
                  or not such reorganization comes within the definition of such
                  term in Code Section 368) or any partial or complete
                  liquidation of the Company, such adjustment shall be made in
                  the number and class of Shares which may be delivered under
                  Section 4.1, in the number and class of and/or price of Shares
                  subject to outstanding Awards granted under the Plan, and in
                  the Award limits set forth in Section 4.1, as may be
                  determined to be appropriate and equitable by the Committee,
                  in its sole discretion, to prevent dilution or enlargement of
                  rights; provided, however, that the number of Shares subject
                  to any Award shall always be a whole number.

5.       ELIGIBILITY AND PARTICIPATION.

         a.       ELIGIBILITY. All Eligible Persons are eligible to participate
                  in this Plan.

         b.       ACTUAL PARTICIPATION. Subject to the provisions of the Plan,
                  the Committee may from time to time in its discretion select
                  Eligible Persons to whom Awards shall be granted and shall
                  determine the nature and amount of each Award.

         c.       PERFORMANCE-BASED AWARDS. The Committee may, in its
                  discretion, grant Awards that are wholly contingent on the
                  attainment of performance goals established by the Committee
                  from time to time. The performance goals may relate to one or
                  more of the following performance measures, as determined by
                  the Committee for each applicable performance period: (i)
                  return to stockholders, (ii) cash flow, (iii) return on
                  equity, (iv) Company created income (for example, income due
                  to Company initiated cost reductions or productivity
                  improvements), (v) sales growth, (vi) earnings and


                                       -7-
<PAGE>

                  earnings growth, (vii) return on assets, (viii) stock price,
                  (ix) earnings per share, (x) market share, (xi) customer
                  satisfaction, and (xii) attaining regulatory approvals or
                  other regulatory benchmarks. Any such performance goals and
                  the applicable performance measures will be determined by the
                  Committee at the time of grant and reflected in an Award
                  Agreement. The number or value of performance-based stock
                  Awards that will be paid out to any Participant at the end of
                  the applicable performance period, which may be one year or
                  longer as determined by the Committee, will depend on the
                  extent to which the Company attains the established
                  performance goals. Awards intended to be performance-based
                  stock Awards shall be subject to such restrictions and
                  conditions as may be required under Section 162(m) to be
                  performance-based compensation thereunder.

6.       STOCK OPTIONS.

         a.       GRANT OF OPTIONS. Subject to the terms and provisions of the
                  Plan, Options may be granted to Participants in such number,
                  and upon such terms, and at any time and from time to time as
                  shall be determined by the Committee.

         b.       AWARD AGREEMENT. Each Option grant shall be evidenced by an
                  Award Agreement that shall specify the Option Price, the
                  duration of the Option, the number of Shares to which the
                  Option pertains, and such other provisions as the Committee
                  shall determine, which need not be uniform for all
                  Participants. The Award Agreement also shall specify whether
                  the Option is intended to be an ISO within the meaning of Code
                  Section 422, or an NQSO whose grant is intended not to fall
                  under the provisions of Code Section 422.

         c.       PROVISIONS FOR NQSOs. Each Stock Option intended to be a
                  Non-Qualified Stock Option shall be subject to the terms and
                  conditions which the Committee determines to be appropriate,
                  subject to the following minimum standards for any such
                  Non-Qualified Stock Option:

                  i.       The option price (per share) of the Shares covered by
                           each Non-Qualified Stock Option shall be determined
                           by the Committee but shall not be less than the par
                           value per share of Common Stock.

                  ii.      Each Award Agreement shall state the date or dates on
                           which it first is exercisable and the date after
                           which it may no longer be exercised, and may provide
                           that the Stock Option rights accrue or become
                           exercisable in installments over a period of months
                           or years, or upon the occurrence of certain
                           conditions or the attainment of stated goals or
                           events; and

                  iii.     Exercise of any Stock Option may be conditioned upon
                           the Participant's execution of a Share purchase
                           agreement in form satisfactory to the Committee
                           providing, among other things, that:

                           (1)      The Participant's or the Participant's
                                    estate, heirs and representatives right to
                                    sell the Shares may be restricted; and


                                       -8-
<PAGE>

                           (2)      The Participant or the Participant's estate,
                                    heirs and representatives may be required to
                                    execute letters of investment intent and
                                    must also acknowledge that the Shares will
                                    bear legends noting any applicable
                                    restrictions.

         d.       PROVISIONS FOR ISOs. Each Stock Option intended to be an
                  Incentive Stock Option shall be issued only to an Employee and
                  be subject to at least the following terms and conditions,
                  with such additional restrictions or changes as the Committee
                  determines are appropriate but not in conflict with Code
                  Section 422 and relevant regulations and rulings of the
                  Internal Revenue Service:

                  i.       The Incentive Stock Option shall meet the minimum
                           standards required of Non-Qualified Stock Options, as
                           described in Section 6.3 except clause (a)
                           thereunder.

                  ii.      Immediately before the Incentive Stock Option is
                           granted, if the Participant owns, directly or by
                           reason of the applicable attribution rules in Code
                           Section 424(d):

                           (1)      Ten percent (10%) or less of the total
                                    combined voting power of all classes of
                                    share capital of the Company or an
                                    Affiliate, the option price per share of the
                                    Shares covered by each Incentive Stock
                                    Option shall not be less than one hundred
                                    percent (100%) of the Fair Market Value per
                                    share of the Shares on the date of the grant
                                    of the Incentive Stock Option.

                           (2)      More than ten percent (10%) of the total
                                    combined voting power of all classes of
                                    share capital of the Company or an
                                    Affiliate, the option price per share of the
                                    Shares covered by each Incentive Stock
                                    Option shall not be less than one hundred
                                    ten percent (110%) of the said Fair Market
                                    Value on the date of grant.

                  iii.     For Participants who own:

                           (1)      Ten percent (10%) or less of the total
                                    combined voting power of all classes of
                                    share capital of the Company or an
                                    Affiliate, each Incentive Stock Option shall
                                    terminate not more than ten (10) years from
                                    the date of the grant or at such earlier
                                    time as the Award Agreement may provide;

                           (2)      More than ten percent (10%) of the total
                                    combined voting power of all classes of
                                    share capital of the Company or an
                                    Affiliate, each Incentive Stock Option shall
                                    terminate not more than five (5) years from
                                    the date of the grant or at such earlier
                                    time as the Award Agreement may provide.


                                       -9-
<PAGE>

                  iv.      The Award Agreements shall restrict the amount of
                           Options which may be exercisable in any calendar year
                           (under this or any other Incentive Stock Option plan
                           of the Company or an Affiliate) so that the aggregate
                           Fair Market Value (determined at the time each
                           Incentive Stock Option is granted) of the stock with
                           respect to which Incentive Stock Options are
                           exercisable for the first time by the Participant in
                           any calendar year does not exceed one hundred
                           thousand dollars ($100,000), provided that this
                           subparagraph shall have no force or effect if its
                           inclusion in the Plan is not necessary for Options
                           issued as Incentive Stock Options to qualify as
                           Incentive Stock Options pursuant to Section 422(d) of
                           the Code.

                  v.       No Incentive Stock Options shall be granted after the
                           date which is the earlier of ten (10) years from the
                           date of the adoption of the Plan by the Company and
                           the date of the approval of this Plan by the
                           shareholders of the Company.

                  vi.      Each Participant who receives an Incentive Stock
                           Option must agree to notify the Company in writing
                           immediately after the Participant makes a
                           Disqualifying Disposition of any shares acquired
                           pursuant to the exercise of an Incentive Stock
                           Option. A Disqualifying Disposition is any
                           disposition (including any sale) of such shares
                           before the later of (i) two years after the date the
                           Participant was granted the Incentive Stock Option,
                           or (ii) one year after the date the Participant
                           acquired shares by exercising the Incentive Stock
                           Option. If the Participant has died before such stock
                           is sold, these holding period requirements do not
                           apply and no Disqualifying Disposition can occur
                           thereafter.

         e.       PAYMENT. Options granted under this Section 6 shall be
                  exercised in accordance with the applicable Award Agreement by
                  the delivery of a proper notice of exercise to the Company,
                  setting forth the number of Shares with respect to which the
                  Option is to be exercised. No shares of Common Stock shall be
                  issued on the exercise of an Option unless the Option Price is
                  paid for in full at the time of exercise. Payment shall be
                  made in cash, which may be paid by check or other instrument
                  acceptable to the Committee. In addition, subject to
                  compliance with applicable laws and regulations and such
                  conditions as the Committee may impose, the Option holder may
                  deliver with his exercise notice irrevocable instructions to a
                  broker to promptly deliver to the Company an amount of sale or
                  loan proceeds sufficient to pay the exercise price. As soon as
                  practicable after receipt of proper notification of exercise
                  and full payment, the Company shall deliver to the
                  Participant, in the Participant's name, Share certificates in
                  an appropriate amount based upon the number of Shares
                  purchased under the Option(s).

         f.       RESTRICTIONS ON SHARE TRANSFERABILITY. The Committee may
                  impose such restrictions on any Shares acquired pursuant to
                  the exercise of an Option granted under this Section 6 as it
                  may deem advisable, including, without limitation,
                  restrictions under applicable federal securities laws, under
                  the requirements of any stock exchange or market upon which
                  such Shares are then listed and/or traded, and under any state
                  securities laws applicable to such Shares.


                                      -10-
<PAGE>

         g.       TERMINATION OF EMPLOYMENT. Each Option, to the extent it has
                  not been previously exercised, shall terminate upon the
                  earliest to occur of: (a) the expiration of the Option period
                  set forth in the Award Agreement; (b) for ISOs, the expiration
                  of three months following the Participant's Retirement
                  (following the Participant's Retirement, NQSOs shall terminate
                  upon the expiration of the Option period set forth in the
                  Option Award Agreement); (c) the expiration of 12 months
                  following the Participant's death or Disability; (d)
                  immediately upon termination for Cause; (e) the expiration of
                  90 days following the Participant's termination of employment
                  for any reason other than Cause, Change in Control, death,
                  Disability, or Retirement; or (f) at such other time or times
                  and on such conditions provided for in the Award Agreement.
                  Upon a termination of employment related to a Change in
                  Control, Options shall be treated in the manner set forth in
                  Section 10.

         h.       NONTRANSFERABILITY OF OPTIONS.

                  i.       INCENTIVE STOCK OPTIONS. No ISO granted under the
                           Plan may be sold, transferred, pledged, assigned or
                           otherwise alienated or hypothecated, other than by
                           will or by the laws of descent and distribution.
                           Further, all ISOs granted to a Participant under the
                           Plan shall be exercisable during his or her lifetime
                           only by such Participant.

                  ii.      NONQUALIFIED STOCK OPTIONS. The Committee may, in its
                           discretion, authorize all or a portion of NQSOs
                           granted to a Participant to be on terms which permit
                           transfer by such Participant to (i) Immediate Family
                           Members, (ii) a trust or trusts for the exclusive
                           benefit of such Immediate Family Members, or (iii) a
                           partnership in which such Immediate Family Members
                           are the only partners, provided that (A) there may be
                           no consideration for any such transfer, (B) the Award
                           Agreement pursuant to which such Options are granted
                           must be approved by the Committee, and must expressly
                           provide for transferability in a manner consistent
                           with this Section, and (C) subsequent transfers of
                           transferred Options shall be prohibited except those
                           by will or the laws of descent and distribution.
                           Following transfer, any such Options shall continue
                           to be subject to the same terms and conditions as
                           were applicable immediately prior to transfer,
                           provided that for purposes of this Plan, the term
                           "Participant" shall be deemed to refer to the
                           transferee. The events of termination of employment
                           shall continue to be applied with respect to the
                           original Participant, following which the Options
                           shall be exercisable by the transferee only to the
                           extent, and for the periods specified in this Section
                           6.8. Notwithstanding the foregoing, should the
                           Committee provide that Options granted be
                           transferable, the Company by such action incurs no
                           obligation to notify or otherwise provide notice to a
                           transferee of early termination of the Option. In the
                           event of a transfer, as set forth above, the original
                           Participant is and will remain subject to and
                           responsible for any applicable withholding taxes upon
                           the exercise of such Options.

7.       RESTRICTED STOCK.


                                      -11-
<PAGE>

         a.       GRANT OF RESTRICTED STOCK. Subject to the terms and provisions
                  of the Plan, the Committee, at any time and from time to time,
                  may grant Shares of Restricted Stock to Participants in such
                  amounts as the Committee shall determine. Without limiting the
                  generality of the foregoing, Restricted Shares may be granted
                  in connection with payouts under other compensation programs
                  of the Company.

         b.       RESTRICTED STOCK AGREEMENT. Each Restricted Stock grant shall
                  be evidenced by a Restricted Stock Award Agreement that shall
                  specify the Period(s) of Restriction, the number of Shares of
                  Restricted Stock granted, and such other provisions as the
                  Committee shall determine.

         c.       TRANSFERABILITY. Except as provided in this Section 7, the
                  Shares of Restricted Stock granted herein may not be sold,
                  transferred, pledged, assigned or otherwise alienated or
                  hypothecated until the end of the applicable Period of
                  Restriction established by the Committee and specified in the
                  Restricted Stock Award Agreement, or upon earlier satisfaction
                  of any other conditions, as specified by the Committee in its
                  sole discretion and set forth in the Restricted Stock Award
                  Agreement. All rights with respect to the Restricted Stock
                  granted to a Participant under the Plan shall be available
                  during his or her lifetime only to such Participant.

         d.       OTHER RESTRICTIONS. Subject to the Plan, the Committee shall
                  impose such other conditions and/or restrictions on any Shares
                  of Restricted Stock granted pursuant to the Plan as it may
                  deem advisable including, without limitation, a requirement
                  that Participants pay a stipulated purchase price for each
                  Share of Restricted Stock, restrictions based upon the
                  achievement of specific performance objectives, time-based
                  restrictions on vesting following the attainment of the
                  performance objectives, and/or restrictions under applicable
                  federal or state securities laws. At the discretion of the
                  Committee, the Company may retain the certificates
                  representing Shares of Restricted Stock in the Company's
                  possession until such time as all conditions and/or
                  restrictions applicable to such Shares have been satisfied.
                  Except as otherwise provided in this Section 7, Shares of
                  Restricted Stock covered by each Restricted Stock grant made
                  under the Plan shall become freely transferable by the
                  Participant after the last day of the applicable Period of
                  Restriction, subject to applicable securities laws.

         e.       VOTING RIGHTS. During the Period of Restriction, Participants
                  holding Shares of Restricted Stock granted hereunder may
                  exercise full voting rights with respect to those Shares.

         f.       DIVIDENDS AND OTHER DISTRIBUTIONS. During the Period of
                  Restriction, Participants holding Shares of Restricted Stock
                  granted hereunder may be credited with regular cash dividends
                  paid with respect to the underlying Shares while they are so
                  held. Such dividends may be paid currently, accrued as
                  contingent cash obligations, or converted into additional
                  shares of Restricted Stock, upon such terms as the Committee
                  establishes. The Committee may apply any restrictions to the
                  dividends that the Committee deems appropriate. In the event
                  that any dividend constitutes a "derivative security" or an
                  "equity security" pursuant to Rule 16(a) under the Exchange
                  Act, such


                                      -12-
<PAGE>

                  dividend shall be subject to a vesting period equal to the
                  remaining vesting period of the Shares of Restricted Stock
                  with respect to which the dividend is paid.

         g.       TERMINATION OF EMPLOYMENT. Upon a Participant's death,
                  Disability, or Retirement, all Restricted Shares shall vest
                  immediately. Each Restricted Stock Award Agreement shall set
                  forth the extent to which the Participant shall have the right
                  to retain unvested Restricted Shares following termination of
                  the Participant's employment with the Company in all other
                  circumstances. Such provisions shall be determined in the sole
                  discretion of the Committee, shall be included in the Award
                  Agreement entered into with each Participant, need not be
                  uniform among all Shares of Restricted Stock issued pursuant
                  to the Plan, and may reflect distinctions based on the reasons
                  for termination of employment.

8.       BENEFICIARY DESIGNATION.

         A Participant under the Plan may make written designation of a
beneficiary on forms prescribed by and filed with the Secretary of the Company.
Such beneficiary, or if no such designation of any beneficiary has been made,
the legal representative of such Participant or such other person entitled
thereto as determined by a court of competent jurisdiction, may exercise, in
accordance with and subject to the provisions of Section 6, any unterminated and
unexpired Option granted to such Participant to the same extent that the
Participant himself could have exercised such Option were he alive or able;
provided, however, that no Option granted under the Plan shall be exercisable
for more Shares than the Participant could have purchased thereunder on the date
his employment by, or other relationship with, the Company and its Subsidiaries
was terminated.

9.       RIGHTS OF ELIGIBLE PERSONS AND PARTICIPANTS.

         Nothing in this Plan or any Award Agreement shall be deemed to: prevent
the Company or an Affiliate from terminating the employment, consultancy or
director status of a Participant; prevent a Participant from terminating his or
her own employment, consultancy or director status; give any Participant a right
to be retained in employment or other service by the Company or any Affiliate
for any period of time; confer on any person any right to be selected as a
Participant.

10.      CHANGE IN CONTROL.

         a.       TREATMENT OF OUTSTANDING AWARDS. Upon the occurrence of a
                  Change in Control, unless otherwise specifically prohibited
                  under applicable laws, or by the rules and regulations of any
                  governing governmental agencies or national securities
                  exchanges:

                  i.       Any and all Options granted hereunder shall become
                           immediately exercisable, and shall remain exercisable
                           throughout their entire term; and

                  ii.      Any restriction periods and restrictions imposed on
                           Shares of Restricted Stock shall lapse; provided,
                           however, that the degree of vesting associated with
                           Restricted Stock which has been conditioned upon the
                           achievement of


                                      -13-
<PAGE>

                           performance conditions pursuant to Section 5.3 herein
                           shall be determined in the manner set forth in
                           Section 7.4 herein.

         b.       TERMINATION, AMENDMENT, AND MODIFICATIONS OF
                  CHANGE-IN-CONTROL PROVISIONS. Notwithstanding any other
                  provision of this Plan or any Award Agreement provision, the
                  provisions of this Section 10 may not be terminated, amended,
                  or modified on or after the date of a Change in Control to
                  affect adversely any Award theretofore granted under the Plan
                  without the prior written consent of the Participant with
                  respect to said Participant's outstanding Awards.

11.      AMENDMENT, MODIFICATION, AND TERMINATION.

         a.       AMENDMENT, MODIFICATION, AND TERMINATION. Subject to Section
                  10.2 herein, the Board or the Committee may at any time and
                  from time to time, alter, amend, suspend or terminate the Plan
                  in whole or in part, except that, without approval of the
                  stockholders of the Company, no such revision or amendment
                  shall increase the number of shares available for grants of
                  ISOs under the Plan or alter the class of participants in the
                  Plan. Notwithstanding the foregoing, neither the Company nor
                  the Board or Committee on its behalf may cancel outstanding
                  Awards and issue substitute Awards in replacement thereof or
                  reduce the exercise price of any outstanding Options without
                  stockholder approval.

         b.       ADJUSTMENT OF AWARDS UPON THE OCCURRENCE OF CERTAIN UNUSUAL OR
                  NONRECURRING EVENTS. The Committee may make adjustments in the
                  terms and conditions of, and the criteria included in, Awards
                  in recognition of unusual or nonrecurring events (including,
                  without limitation, the events described in Section 4.2
                  hereof) affecting the Company or the financial statements of
                  the Company or of changes in applicable laws, regulations, or
                  accounting principles, whenever the Committee determines that
                  such adjustments are appropriate in order to prevent dilution
                  or enlargement of the benefits or potential benefits intended
                  to be made available under the Plan.

         c.       AWARDS PREVIOUSLY GRANTED. No termination, amendment, or
                  modification of the Plan shall adversely affect in any
                  material way any Award previously granted under the Plan,
                  without the written consent of the Participant holding such
                  Award.

12.      WITHHOLDING.

         a.       TAX WITHHOLDING. The Company shall have the power and the
                  right to deduct or withhold, or require a Participant to remit
                  to the Company, an amount sufficient to satisfy federal,
                  state, and local taxes, domestic or foreign, required by law
                  or regulation to be withheld with respect to any taxable event
                  arising as a result of this Plan.

         b.       SHARE WITHHOLDING. To the extent provided by the Committee, a
                  Participant may elect to have any distribution to be made
                  under this Plan to be withheld or to surrender to the Company
                  shares of Common Stock already owned by the Participant to
                  fulfill any tax withholding obligation.


                                      -14-
<PAGE>

13.      SUCCESSORS.

         All obligations of the Company under the Plan with respect to Awards
granted hereunder shall be binding on any successor to the Company, whether the
existence of such successor is the result of a direct or indirect purchase of
all or substantially all of the business and/or assets of the Company, or a
merger, consolidation or otherwise.

14.      LEGAL CONSTRUCTION.

         a.       GENDER AND NUMBER. Except where otherwise indicated by the
                  context, any masculine term used herein also shall include the
                  feminine; the plural shall include the singular; and, the
                  singular shall include the plural.

         b.       SEVERABILITY. In the event any provision of the Plan shall be
                  held illegal or invalid for any reason, the illegality or
                  invalidity shall not affect the remaining parts of the Plan,
                  and the illegal or invalid provision shall be modified to the
                  extent necessary to be legal and valid and shall be enforced
                  as modified.

         c.       REQUIREMENTS OF LAW. The granting of Awards and the issuance
                  of Shares under the Plan shall be subject to all applicable
                  laws, rules, and regulations, and to such approvals by any
                  governmental agencies or national securities exchanges as may
                  be required.

         d.       SECURITIES LAW COMPLIANCE. With respect to Insiders,
                  transactions under this Plan are intended to comply with all
                  applicable conditions of Rule 16b-3 or its successors under
                  the Exchange Act. To the extent any provision of the Plan or
                  action by the Committee fails to so comply, it shall be deemed
                  null and void, to the extent permitted by law and deemed
                  advisable by the Committee.

         e.       GOVERNING LAW. To the extent not preempted by federal law, the
                  Plan, and all agreements hereunder, shall be construed in
                  accordance with and governed by the laws of the state of
                  Nevada.

15.      RIGHTS AS A SHAREHOLDER.

         No Participant to whom an Award has been granted shall have rights as a
shareholder with respect to any Shares covered by such Award, except after due
exercise of the Award and tender of the full purchase price for any Shares being
purchased pursuant to such exercise and registration of the Shares in the
Company's share register in the name of the Participant. Nothing in this Plan
shall affect a Participant's employment or other engagement by the Company,
including the Company's right to terminate such employment or engagement.

16.      PURCHASE FOR INVESTMENT.

         a.       Unless the offering and sale of the Shares to be issued upon
                  the particular exercise of an Option shall have been
                  effectively registered under the Securities Act of 1933 (the
                  "1933


                                      -15-
<PAGE>

                  Act"), the Company shall be under no obligation to issue the
                  Shares covered by such exercise unless and until the person(s)
                  who exercise such Option shall represent and warrant to the
                  Company, prior to the receipt of such Shares, that such
                  person(s) are acquiring such Shares for their own respective
                  accounts, for investment, and not with a view to, or for sale
                  in connection with, the distribution of any such Shares. The
                  person(s) acquiring such Shares shall be bound by the
                  provisions of the following legend which shall be endorsed
                  upon the certificate(s) evidencing their Shares issued
                  pursuant to such exercise or such grant:

                  The shares evidenced by this certificate have not been
                  registered under the Securities Act of 1933, as amended, or
                  under state securities laws to the extent applicable. The
                  shares may not be sold, offered for sale, or otherwise
                  transferred in the absence of an effective registration
                  statement under said Act (and any registration or
                  qualification as may be required under such state laws) or an
                  opinion of counsel satisfactory to the company and its counsel
                  that such registration or qualification is not required.

         b.       The Company may delay issuance of the Shares until completion
                  of any action or obtaining of any consent which the Company
                  deems necessary under any applicable law (including, without
                  limitation, state securities or "blue sky" laws).

                                      -16-


<PAGE>

                       PHOTOGEN TECHNOLOGIES, INC.
                      ANNUAL MEETING OF STOCKHOLDERS

                             MAY 17, 2000

                                PROXY

                SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned hereby appoints Timothy Scott, Ph.D. and Robert
Weinstein, M.D., or either one of them acting singly in the absence of the
other, with full power of substitution, the proxy and proxies of the
undersigned to vote the shares of Common Stock, par value $.001 per share, of
Photogen Technologies, Inc. ("Photogen"), which the undersigned could vote,
and with all power the undersigned would possess, if personally present at
the Annual Meeting of Stockholders of Photogen to be held at the Ritz Carlton
Hotel, 160 East Pearson Street, Chicago, Illinois, on Wednesday, May 17, 2000
at 10:00 a.m., Chicago Time, and any adjournment thereof, all as set forth in
the accompanying Proxy Statement:

             (Continued and to be dated and signed on other side)
<PAGE>

                        PHOTOGEN TECHNOLOGIES, INC.
     PLEASE MARK VOTE IN OVAL IN THE FOLLOWING MANNER USING DARK INK ONLY

                                                                     FOR All
                                               FOR      WITHHELD     Except
                                               All        All        as noted
1.   Election of Directors.                    / /        / /          / /
     INSTRUCTION: TO WITHHOLD AUTHORITY
     TO VOTE FOR ANY INDIVIDUAL NOMINEE,
     MARK A LINE THROUGH THE NOMINEE'S NAME
     IN THE LIST BELOW.

     Eric A. Wachter, Ph.D.        Theodore Tannebaum
     Robert J. Weinstein, M.D.     Eugene Golub
     Lester H. McKeever, Jr.       Vincent L. Fabiano

2.   Approval of an amendment to Article        FOR     AGAINST     ABSTAIN
     Fifth of the Company's Articles of         / /       / /         / /
     Incorporation increasing the size of
     the Board of Directors from six to
     seven directors and providing that all
     vacancies of the Board of Directors
     shall be filled in the manner
     provided in the Company's Bylaws.

3.   Approval of the 2000 Long Term             FOR     AGAINST     ABSTAIN
     Incentive Compensation Plan                / /       / /         / /

4.   Ratification of BDO Seidman, LLP as        FOR     AGAINST     ABSTAIN
     the Company's independent public           / /       / /         / /
     accountants for 2000.

5.  In their discretion, to act upon any matters incidental to the foregoing
    and such other business as may properly come before the Annual Meeting, or
    any adjournment thereof.

This Proxy when properly executed, will be voted in the manner directed
herein by the undersigned stockholder.  IF NO DIRECTION IS MADE, THIS PROXY
WILL BE VOTED FOR ITEMS 1, 2, 3 AND 4 ABOVE AND IN THE DISCRETION OF THE
APPOINTED PROXIES UPON SUCH OTHER BUSINESS AS MAY PROPERLY COME BEFORE THE
MEETING.  Any holder who wishes to withhold the discretionary authority
referred to in Item 5 above should mark a line through the entire Item.

The signer hereby revokes all proxies heretofore given by the signer to vote
at said meeting or any adjournments thereof.

Dated_________________________________, 2000

____________________________________________
               Signature(s)

____________________________________________
               Signature(s)

(Please sign exactly and as fully as your name appears on your stock
certificate. If shares are held jointly, each stockholder must sign.
When signing as an attorney, executor, administrator, trustee
or guardian, please give full title as such.)

                            - FOLD AND DETACH HERE -

   PLEASE MARK, SIGN, DATE AND RETURN PROMPTLY, USING THE ENCLOSED ENVELOPE.

                            NO POSTAGE IS REQUIRED.



© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission