DREYFUS GNMA FUND INC
24F-2NT, 1995-06-21
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                             DREYFUS GNMA FUND, INC.
                                200 PARK AVENUE
                              NEW YORK, NY  10166


Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, NW
Washington, DC  20549


      24f-2 Notice - DREYFUS GNMA FUND, INC.
      Registration Statement No. 2-95553 - CIK #762156

Gentlemen:

  On May 22, 1985, the Registration Statement of Dreyfus GNMA Fund, Inc. was
declared effective by the SEC.  The Registration Statement represented the
Fund's election to register an indefinite number of shares and this Notice,
filed pursuant to Rule 24f-2, is for the fiscal year ended April 30, 1995.

  The following information is furnished:

  (a) Shares registered under Securities Act
      of 1933 other than pursuant to Rule 24f(2)
      which remained unsold on May 1, 1994:                       83,848,718

  (b) Shares registered during fiscal year
      other than pursuant to Section 24(f)

  Post-Effective Amendment No. 16 effective 12/14/94:             16,293,771
                                                                 -----------



  Total of (a) and (b)                                           100,142,489
                                                                 ===========


                                                  SHARES        DOLLAR AMOUNT

  (c) Total number of shares sold during
      fiscal year ended 4/30/95 subject
      to registration under Rule 24f-2:        6,996,614     $    99,068,452

  (d) Less shares redeemed during
      fiscal year ended 4/30/95:              22,822,022         322,130,878
                                            -------------    ----------------

  Net Sales During Fiscal Year [(c)-(d)]:   ( 15,825,408)    $(  223,062,426)
                                             ==============  ================

  Less shares registered other than
  pursuant to Section 24(f) [(a) + (b)]        100,142,489     1,447,143,410
                                             --------------  ---------------

  Unsold balance of registered shares         (115,967,897)  $(1,670,205,836)
                                             ============== =================


                                          -2-


                                   CALCULATION OF FEE

  Since the shares redeemed exceed the shares sold, no registration fee is
required.  An opinion of counsel is enclosed.


                                                   Very truly yours,

JJP/ems

                                                   John J. Pyburn
cc:  Mr. J. deMichaelis, SEC                       Assistant Treasurer
     Ms. R. McLaughlin, E&Y









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