DREYFUS GNMA FUND INC
497, 2000-12-15
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GNMA265SP1200

11/30/00

Dreyfus

GNMA Fund, Inc.

Investing in Ginnie Maes and other mortgage-related securities for current
income


PROSPECTUS September 1, 2000
             As revised, December 15, 2000


As with all mutual funds, the Securities and Exchange Commission has not
approved or disapproved these securities or passed upon the adequacy of this
prospectus. Any representation to the contrary is a criminal offense.

<PAGE>


                                 Contents

                                  THE FUND
----------------------------------------------------

                             2    Goal/Approach

                             3    Main Risks

                             4    Past Performance

                             5    Expenses

                             6    Management

                             7    Financial Highlights

                                  YOUR INVESTMENT
--------------------------------------------------------------------

                             8    Account Policies

                            11    Distributions and Taxes

                            12    Services for Fund Investors

                            14    Instructions for Regular Accounts

                            16    Instructions for IRAs

                                  FOR MORE INFORMATION
-------------------------------------------------------------------------------

                                  Back Cover

What every investor should know about the fund

Information for managing your fund account

Where to learn more about this and other Dreyfus funds

<PAGE>


                                                                     The Fund
                                                       Dreyfus GNMA Fund, Inc.
                                               --------------------------------
                                                          Ticker Symbol: DRGMX

GOAL/APPROACH

The  fund  seeks  as  high  a  level of current income as is consistent with the
preservation  of  capital. To pursue this goal, the fund invests at least 65% of
its  net assets in GNMA certificates (popularly called "Ginnie Maes"), which are
guaranteed  as  to  timely  payment  of principal and interest by the Government
National    Mortgage    Association.

The  fund  also may invest in other mortgage-related securities, including those
issued by government-related organizations such as the Federal National Mortgage
Association  and  the Federal Home Loan Mortgage Corporation, and collateralized
mortgage    obligations    (CMOs)   , including   residential   and   commercial
mortgage-backed  securities issued by governmental agencies or private entities.
The  fund can invest in privately issued mortgage-backed securities with a "BBB"
or  higher  credit  quality,  but  currently  intends  to  invest  in only those
securities with an "A" or higher credit quality.

The  fund  also  may  purchase other securities issued or guaranteed by the U.S.
government  or  its  agencies or instrumentalities, such as U.S. Treasury bills,
notes  and  bonds.  It  also may purchase asset-backed securities and enter into
repurchase    agreements.

INFORMATION  ON  THE  FUND' S RECENT STRATEGIES AND HOLDINGS CAN BE FOUND IN THE
CURRENT ANNUAL/SEMIANNUAL REPORT (SEE BACK COVER).

Concepts to understand

GINNIE MAES: securities backed by a pool of residential mortgages, which "pass
through" to investors the interest and principal payments of homeowners. The
Government National Mortgage Association guarantees that investors will receive
timely principal and interest payments even if homeowners do not make mortgage
payments on time.

CMOS: multi-class bonds backed by pools of mortgage pass-through securities or
mortgage loans; either residential or commercial. CMOs may be issued by U.S.
government agencies or private entities.

COMMERCIAL MORTGAGE-BACKED SECURITIES: a CMO backed by loans on apartment
buildings, office buildings or shopping centers.



2
<PAGE 2>

MAIN RISKS

A  security guaranteed by the U.S. government is guaranteed only as to principal
and  interest.  Neither  the  market value of such security nor the fund's share
price  is  guaranteed.  The  value of your investment in the fund could go up or
down, which means that you could lose money.

While  prices  of  fixed-income  securities tend to move inversely with interest
rate changes, mortgage-related securities may react differently to interest rate
changes than other bonds, because of prepayments and other factors. For example,
when  interest  rates  fall,  mortgage  pass-through  securities may be paid off
earlier  than  expected,  and the fund may reinvest those assets at lower rates.
This  factor  lessens  price-appreciation potential from interest rate declines.
When  rates  rise, prices may decline less, given their generally higher coupon.
Also,  when rates rise it may effectively lengthen a mortgage-related security's
expected  maturity  and cause the value of the security to fluctuate more widely
in response to interest rate changes.

If  the market for privately issued securities in which the fund invests becomes
" illiquid,"  typically  when  there  are  many more sellers than buyers for the
securities,  the value of those securities, and the fund's share price, may fall
dramatically.

Privately  issued  mortgage-related  securities also are subject to credit risks
associated  with  the  underlying  mortgage  properties  and,  during  difficult
economic conditions, may be more volatile and less liquid than more traditional,
government-backed debt securities.

Other potential risks

Most mortgage- and asset-backed securities are a form of derivative. The fund,
at times, may also invest in other derivative securities, such as options and
futures. Derivatives are used primarily to hedge the fund's portfolio, but may
be used to increase returns; however, such practices may lower returns or
increase volatility. Derivatives can be illiquid, and a small investment in
certain derivatives could have a potentially large impact on the fund's
performance.

The fund may buy securities on a forward-commitment basis, and enter into
reverse repurchase agreements, which are forms of borrowing that can increase
the fund's overall price volatility.

                                                                     The Fund 3



<PAGE 3>

PAST PERFORMANCE

The  bar  chart and table below show some of the risks of investing in the fund.
The bar chart shows the changes in the fund's performance from year to year. The
table  compares  the  fund' s  average annual total return to that of the Lehman
Brothers  GNMA  Index, an unmanaged Ginnie Mae performance benchmark. Of course,
past performance is no guarantee of future results.
                        --------------------------------------------------------

Year-by-year total return AS OF 12/31 EACH YEAR (%)

9.75    14.50   6.34    7.16    -2.77   15.11   4.41    8.83    4.16    1.31
90      91      92      93      94      95      96      97      98      99


BEST QUARTER:                                 Q3 '91         +4.96%

WORST QUARTER:                                Q1 '94         -2.36%

THE FUND'S YEAR-TO-DATE TOTAL RETURN AS OF 6/30/00 WAS 3.98%.
                        --------------------------------------------------------

Average annual total return AS OF 12/31/99

<TABLE>
<CAPTION>


                                                1 Year               5 Years            10 Years
                    ---------------------------------------------------------------------------------------

<S>                                             <C>                 <C>                  <C>
FUND                                            1.31%               6.66%                6.75%

LEHMAN

BROTHERS

GNMA INDEX                                      1.93%               8.08%                7.87%

</TABLE>


What this fund is --
and isn't

This fund is a mutual fund:
a pooled  investment  that is  professionally  managed  and  gives  you the
opportunity to participate in financial markets.  It strives to reach its stated
goal, although as with all mutual funds, it cannot offer guaranteed results.

An  investment  in this fund is not a bank  deposit.  It is not  insured or
guaranteed  by the FDIC or any other  government  agency.  It is not a  complete
investment  program.  You could lose  money in this fund,  but you also have the
potential to make money.






4
<PAGE 4>

EXPENSES

As  an  investor, you pay certain fees and expenses in connection with the fund,
which  are described in the table below. Annual fund operating expenses are paid
out of fund assets, so their effect is included in the share price. The fund has
no sales charge (load).
                        --------------------------------------------------------

Fee table


ANNUAL FUND OPERATING EXPENSES
% OF AVERAGE DAILY NET ASSETS
Management fees                                                            0.60%

Rule 12b-1 fee                                                             0.16%

Other expenses                                                             0.16%

                         -------------------------------------------------------

TOTAL                                                                      0.92%
                        --------------------------------------------------------

Expense example

1 Year                  3 Years                 5 Years                 10 Years
--------------------------------------------------------------------------------

$94                  $293                        $509                   $1,131

                        This  example  shows what you could pay in expenses over
                        time.  It  uses  the  same hypothetical conditions other
                        funds   use   in  their  prospectuses:  $10,000  initial
                        investment,  5% total return each year and no changes in
                        expenses.  The  figures  shown would be the same whether
                        you  sold  your  shares  at  the end of a period or kept
                        them.   Because  actual  return  and  expenses  will  be
                        different, the example is for comparison only.

Concepts to understand

MANAGEMENT FEE: the fee paid to Dreyfus for managing the fund's portfolio and
assisting in all aspects of the fund's operations.


RULE 12B-1 FEE: a fee of up to 0.20% used to reimburse the fund's distributor
for distributing fund shares, servicing shareholder accounts, and advertising
and marketing. Because this fee is paid out of the fund's assets on an ongoing
basis, over time it will increase the cost of your investment and may cost you
more than paying other types of sales charges.


OTHER EXPENSES: fees paid by the fund for miscellaneous items such as transfer
agency, custody, professional and registration fees.

                                                                      The Fund 5





<PAGE 5>

MANAGEMENT

The investment adviser for the fund is The Dreyfus Corporation, 200 Park Avenue,
New  York,  New  York  10166.  Founded  in  1947, Dreyfus manages more than $134
billion  in  over 160 mutual fund portfolios. For the past fiscal year, the fund
paid  Dreyfus a management fee at the annual rate of 0.60% of the fund's average
daily  net  assets.  Dreyfus  is  the  primary  mutual  fund  business of Mellon
Financial  Corporation,  a  global financial services company with approximately
$2.8  trillion  of assets under management, administration or custody, including
approximately  $521 billion under management. Mellon provides wealth management,
global  investment  services  and  a comprehensive array of banking services for
individuals, businesses and institutions. Mellon is headquartered in Pittsburgh,
Pennsylvania.

The  fund, Dreyfus and Dreyfus Service Corporation (the fund's distributor) each
have  adopted a code of ethics that permits its personnel, subject to such code,
to  invest  in securities, including securities that may be purchased or held by
the  fund.  The  Dreyfus  code  of  ethics  restricts  the  personal  securities
transactions  of  its  employees,  and  requires  portfolio  managers  and other
investment  personnel  to  comply  with  the  code's preclearance and disclosure
procedures.  Its  primary  purpose is to ensure that personal trading by Dreyfus
employees does not disadvantage any Dreyfus-managed fund.


Portfolio manager

Michael Hoeh has been the fund's primary portfolio manager since March 1997 and
has been employed by Dreyfus since October 1996. Prior to joining Dreyfus, Mr.
Hoeh was senior vice president of the portfolio management division of ARM
Capital Advisors, Inc.



6
<PAGE 6>

FINANCIAL HIGHLIGHTS

This  table  describes  the fund's performance for the fiscal periods indicated.
" Total  return" shows how much your investment in the fund would have increased
(or decreased) during each period, assuming you had reinvested all dividends and
distributions.  These  figures  have been independently audited by Ernst & Young
LLP,  whose  report,  along with the fund's financial statements, is included in
the annual report.

<TABLE>
<CAPTION>


                                                                YEAR ENDED APRIL 30,

                                        2000           1999            1998            1997           1996
---------------------------------------------------------------------------------------------------------

PER-SHARE DATA ($)

<S>                                     <C>             <C>            <C>             <C>            <C>
Net asset value, beginning of period    14.54           14.99          14.44           14.50          14.32

Investment operations:

      Investment income -- net            .90             .92            .91             .92            .96

      Net realized and unrealized gain
      (loss) on investments              (.65)           (.46)           .55            (.05)           .18

Total from investment operations          .25             .46           1.46             .87           1.14

Distributions:

      Dividends from investment
      income -- net                      (.90)           (.91)          (.91)           (.93)          (.96)

Net asset value, end of period          13.89           14.54          14.99           14.44          14.50

Total return (%)                         1.75            3.17          10.38            6.17           8.11
---------------------------------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA

Ratio of expenses
to average net assets (%)                 .92             .94            .96             .96            .96

Ratio of interest expense
and loan commitment fees
to average net assets (%)                  --             .25             --              --             --

Ratio of net investment income
to average net assets (%)                6.40            6.19           6.16            6.38           6.57

Portfolio turnover rate (%)            420.18          206.15         342.71          323.99         144.43
--------------------------------------------------------------------------------------------------------

Net assets, end of period
($ x 1,000)                           910,969       1,068,347      1,172,792       1,240,459      1,373,618

</TABLE>



                                                                      The Fund 7



<PAGE 7>

                                                                Your Investment

ACCOUNT POLICIES

Buying shares

YOU  PAY  NO SALES CHARGES to invest in this fund. Your price for fund shares is
the  fund's net asset value per share (NAV), which is generally calculated as of
the  close  of trading on the New York Stock Exchange (usually 4:00 p.m. Eastern
time)  every day the exchange is open. Your order will be priced at the next NAV
calculated  after  your  order is accepted by the fund's transfer agent or other
authorized  entity.  The fund's investments are generally valued based on market
value or, where market quotations are not readily available, based on fair value
as determined in good faith by the fund's board.
                        --------------------------------------------------------

Minimum investments

                                                Initial      Additional
                        --------------------------------------------------------

REGULAR ACCOUNTS                                $2,500       $100
                                                             $500 FOR
                                                             TELETRANSFER
INVESTMENTS

TRADITIONAL IRAS                                $750         NO MINIMUM

SPOUSAL IRAS                                    $750         NO MINIMUM

ROTH IRAS                                       $750         NO MINIMUM

EDUCATION IRAS                                  $500         NO MINIMUM
                                                             AFTER THE FIRST
YEAR

DREYFUS AUTOMATIC                               $100         $100
INVESTMENT PLANS

                        All  investments  must  be  in U.S. dollars. Third-party
                        checks  cannot be accepted. You may be charged a fee for
                        any  check  that  does  not  clear. Maximum TeleTransfer
                        purchase is $150,000 per day.

Concepts to understand

NET ASSET VALUE (NAV): a mutual fund's share price on  a given day. A fund's NAV
is calculated by dividing the value of its net assets by the number of existing
shares.




8

<PAGE 8>

Selling shares

YOU  MAY  SELL (REDEEM) SHARES AT ANY TIME. Your shares will be sold at the next
NAV  calculated  after  your  order  is accepted by the fund's transfer agent or
other  authorized  entity.  Any certificates representing fund shares being sold
must  be  returned  with  your  redemption request. Your order will be processed
promptly and you will generally receive the proceeds within a week.

BEFORE  SELLING  OR  WRITING A CHECK against shares recently purchased by check,
TeleTransfer or Automatic Asset Builder, please note that:

(pound)  if  you  send a written request to sell such shares, the  fund  may
         delay  sending  the  proceeds  for  up to eight business days following
         the purchase of those shares

(pound)  the  fund  will  not  honor  redemption  checks,  or process  wire,
         telephone or TeleTransfer redemption requests, for up to eight
         business days following the purchase of those shares
                        --------------------------------------------------------

Limitations on selling shares by phone

Proceeds
sent by                                   Minimum       Maximum
                        --------------------------------------------------------

CHECK                                     NO MINIMUM    $250,000 PER DAY

WIRE                                      $1,000        $500,000 FOR JOINT
ACCOUNTS
                                                        EVERY 30 DAYS

TELETRANSFER                              $500          $500,000 FOR JOINT
ACCOUNTS
                                                        EVERY 30 DAYS


Written sell orders

Some circumstances require written sell orders along with signature guarantees.
These include:

(pound) amounts of $10,000 or more on accounts whose address has been changed
        within the last 30 days

(pound) requests to send the proceeds to a different  payee or address

Written sell orders of $100,000 or more must also be signature guaranteed.

A SIGNATURE GUARANTEE helps protect against fraud. You can obtain one from most
banks or securities dealers, but not from a notary public. For joint accounts,
each signature must be guaranteed. Please call us to ensure that your signature
guarantee will be processed correctly.

                                                               Your Investment 9



<PAGE 9>

ACCOUNT POLICIES (CONTINUED)

General policies

IF YOUR ACCOUNT FALLS BELOW $500, the fund may ask you to increase your balance.
If  it  is  still  below $500 after 45 days, the fund may close your account and
send you the proceeds.

UNLESS  YOU  DECLINE  TELEPHONE  PRIVILEGES  on  your  application,  you  may be
responsible  for  any  fraudulent  telephone  order  as  long  as  Dreyfus takes
reasonable    measures    to    verify    the    order.

THE FUND RESERVES THE RIGHT TO:

(pound)   refuse  any  purchase  or exchange request that
          could  adversely  affect  the  fund  or  its operations,
          including those from any individual or group who, in the
          fund' s  view,  is likely to engage in excessive trading
          (usually  defined as more than four exchanges out of the
          fund within a calendar year)

(pound)   refuse any purchase or exchange request in excess of
          1% of the fund's total assets

(pound)   change  or  discontinue  its  exchange privilege, or
          temporarily suspend this privilege during unusual market conditions

(pound)   change its minimum investment amounts

(pound)   delay  sending  out  redemption  proceeds  for up to
          seven days (generally applies only in cases of very large redemptions,
          excessive trading or during unusual market conditions)

The  fund  also  reserves the right to make a "redemption in kind" -- payment in
portfolio  securities  rather  than  cash  -- if the amount you are redeeming is
large  enough to affect fund operations (for example, if it represents more than
1% of the fund's assets).

Third-party investments

If you invest through a third party (rather than directly with Dreyfus), the
policies and fees may be different than those described here. Banks, brokers,
401(k) plans, financial advisers and financial supermarkets may charge
transaction fees and may set different minimum investments or limitations on
buying or selling shares. Consult a representative of your plan or financial
institution if in doubt.

10

<PAGE 10>


DISTRIBUTIONS AND TAXES

THE  FUND USUALLY PAYS ITS SHAREHOLDERS DIVIDENDS from its net investment income
once a month, and distributes any net capital gains it has realized once a year.
Your  distributions  will be reinvested in the fund unless you instruct the fund
otherwise. There are no fees or sales charges on reinvestments.

FUND  DIVIDENDS  AND  DISTRIBUTIONS  ARE  TAXABLE to most investors (unless your
investment  is in an IRA or other tax-advantaged account). The tax status of any
distribution  is  the  same regardless of how long you have been in the fund and
whether  you  reinvest  your  distributions  or  take  them in cash. In general,
distributions are federally taxable as follows:
                        --------------------------------------------------------

Taxability of distributions

Type of                                    Tax rate for    Tax rate for
distribution                               15% bracket     28% bracket or above
                        --------------------------------------------------------

INCOME                                     ORDINARY        ORDINARY
DIVIDENDS                                  INCOME RATE     INCOME RATE

SHORT-TERM                                 ORDINARY        ORDINARY
CAPITAL GAINS                              INCOME RATE     INCOME RATE

LONG-TERM
CAPITAL GAINS                              10%             20%

The  tax  status  of  your  dividends and distributions will be detailed in your
annual tax statement from the fund.

Because everyone's tax situation is unique, always consult your tax professional
about federal, state and local tax consequences.


Taxes on transactions

Except in tax-advantaged accounts, any sale or exchange of fund shares,
including through the checkwriting privilege, may generate a tax liability. Of
course, withdrawals or distributions from tax-deferred accounts are taxable when
received.

The table at right also can provide a guide for your potential tax liability
when selling or exchanging fund shares. "Short-term capital gains" applies to
fund shares sold or exchanged up to 12 months after buying them. "Long-term
capital gains" applies to shares sold or exchanged after 12 months.


                                                              Your Investment 11




<PAGE 11>

SERVICES FOR FUND INVESTORS

Automatic services

BUYING  OR  SELLING  SHARES  AUTOMATICALLY  is  easy with the services described
below.  With  each service, you select a schedule and amount, subject to certain
restrictions.  You can set up most of these services with your application or by
calling 1-800-645-6561.
                        --------------------------------------------------------

For investing

DREYFUS AUTOMATIC                             For making automatic investments
ASSET BUILDER((reg.tm))                       from a designated bank account.

DREYFUS PAYROLL                               For making automatic investments
SAVINGS PLAN                                  through a payroll deduction.

DREYFUS GOVERNMENT                            For making automatic investments
DIRECT DEPOSIT                                from your federal employment,
PRIVILEGE                                     Social Security or other regular
                                              federal government check.

DREYFUS DIVIDEND                              For automatically reinvesting the
SWEEP                                         dividends and distributions from
                                              one Dreyfus fund into another
                                              (not available for IRAs).
                        --------------------------------------------------------

For exchanging shares

DREYFUS AUTO-                                 For making regular exchanges
EXCHANGE PRIVILEGE                            from one Dreyfus fund into
                                              another.
                        --------------------------------------------------------

For selling shares

DREYFUS AUTOMATIC                             For making regular withdrawals
WITHDRAWAL PLAN                               from most Dreyfus funds.


Dreyfus Financial Centers

Through a nationwide network of Dreyfus Financial Centers, Dreyfus offers a full
array of investment services and products. This includes information on mutual
funds, brokerage services, tax-advantaged products and retirement planning.

Experienced financial consultants can help you make informed choices and provide
you with personalized attention in handling account transactions. The Financial
Centers also offer informative seminars and events. To find the Financial Center
nearest you, call 1-800-499-3327.





12
<PAGE 12>

Checkwriting privilege

YOU MAY WRITE REDEMPTION CHECKS against your account in amounts of $500 or more.
These  checks  are  free;  however,  a  fee may be charged if you request a stop
payment  or  if  the  transfer  agent  cannot  honor  a  redemption check due to
insufficient  funds  or another valid reason. Please do not postdate your checks
or use them to close your account.

                        Exchange privilege

YOU  CAN EXCHANGE SHARES worth $500 or more (no minimum for retirement accounts)
from  one Dreyfus fund into another. You can request your exchange in writing or
by phone. Be sure to read the current prospectus for any fund into which you are
exchanging  before  investing.  Any  new account established through an exchange
will  have  the  same  privileges  as your original account (as long as they are
available). There is currently no fee for exchanges, although you may be charged
a sales load when exchanging into any fund that has one.

Dreyfus TeleTransfer privilege

TO  MOVE  MONEY  BETWEEN  YOUR BANK ACCOUNT and your Dreyfus fund account with a
phone  call, use the Dreyfus TeleTransfer privilege. You can set up TeleTransfer
on  your  account  by  providing  bank  account  information  and  following the
instructions on your application.

24-hour automated account access

YOU  CAN  EASILY  MANAGE  YOUR  DREYFUS  ACCOUNTS,  check your account balances,
transfer  money  between your Dreyfus funds, get price and yield information and
much more -- when it's convenient for you -- by calling 1-800-645-6561.

Retirement plans

Dreyfus offers a variety of retirement plans, including traditional, Roth and
Education IRAs. Here's where you call for information:

(pound)  for traditional, rollover, Roth and Education IRAs, call 1-800-645-656

(pound)  for SEP-IRAs, Keogh accounts, 401(k) and 403(b) accounts,
         call 1-800-358-0910


                                                              Your Investment 13

<PAGE 13>


 INSTRUCTIONS FOR REGULAR ACCOUNTS

   TO OPEN AN ACCOUNT

            In Writing

   Complete the application.

   Mail your application and a check to:
   The Dreyfus Family of Funds
   P.O. Box 9387, Providence, RI 02940-9387


TO ADD TO AN ACCOUNT

Fill out an investment slip, and write your account number on your check.

Mail the slip and the check to:
The Dreyfus Family of Funds
P.O. Box 105,
Newark, NJ 07101-0105


           By Telephone

   WIRE  Have your bank send your
investment to The Bank of New York, with these instructions:

   * ABA# 021000018

   * DDA# 8900051973

   * the fund name

   * your Social Security or tax ID number

   * name(s) of investor(s)

   Call us to obtain an account number. Return your application.


WIRE  Have your bank send your investment to The Bank of New York, with these
instructions:

* ABA# 021000018

* DDA# 8900051973

* the fund name

* your account number

* name(s) of investor(s)

ELECTRONIC CHECK  Same as wire, but insert "1111" before your account number.

TELETRANSFER  Request TeleTransfer on your application. Call us to request your
transaction.

           Automatically

   WITH AN INITIAL INVESTMENT  Indicate
on your application which automatic service(s) you want. Return your application
with your investment.

   WITHOUT ANY INITIAL INVESTMENT  Check the Dreyfus Step Program option on your
application. Return your application, then complete the additional materials
when they are sent to you.

ALL SERVICES  Call us to request a form to add any automatic investing service
(see "Services for Fund Investors"). Complete and return the forms along with
any other required materials.

           Via the Internet

   COMPUTER  Visit the Dreyfus Web site http://www.dreyfus.com and follow the
instructions to download an account application.








14

<PAGE 14>

TO SELL SHARES

Write a redemption check OR write a letter of instruction that includes:

* your name(s) and signature(s)

* your account number

* the fund name

* the dollar amount you want to sell

* how and where to send the proceeds

Obtain a signature guarantee or other documentation, if required (see "Account
Policies -- Selling Shares").

Mail your request to:
The Dreyfus Family of Funds
P.O. Box 9671, Providence, RI 02940-9671

WIRE  Be sure the fund has your bank account information on file. Call us to
request your transaction. Proceeds will be wired to your bank.

TELETRANSFER  Be sure the fund has your bank account information on file. Call
us to request your transaction. Proceeds will be sent to your bank by electronic
check.

CHECK  Call us to request your transaction. A check will be sent to the address
of record.

DREYFUS AUTOMATIC WITHDRAWAL PLAN  Call us to request a form to add the plan.
Complete the form, specifying the amount and frequency of withdrawals you would
like.

Be sure to maintain an account balance of $5,000 or more.


  To reach Dreyfus, call toll free in the U.S.

  1-800-645-6561

  Outside the U.S. 516-794-5452

  Make checks payable to:

  THE DREYFUS FAMILY OF FUNDS

  You also can deliver requests to any Dreyfus Financial Center. Because
  processing time may vary, please ask the representative when your account will
  be credited or debited.

Concepts to understand

WIRE TRANSFER: for transferring money from one financial institution to another.
Wiring is the fastest way to move money, although your bank may charge a fee to
send or receive wire transfers. Wire redemptions from the fund are subject to a
$1,000 minimum.

ELECTRONIC CHECK: for transferring money out of a bank account. Your transaction
is entered electronically, but may take up to eight business days to clear.
Electronic checks usually are available without a fee at all Automated Clearing
House (ACH) banks.

                                                              Your Investment 15



<PAGE 15>

 INSTRUCTIONS FOR IRAS

   TO OPEN AN ACCOUNT

           In Writing

   Complete an IRA application, making sure to specify the fund name and to
indicate the year the contribution is for.

   Mail your application and a check to:
   The Dreyfus Trust Company, Custodian
   P.O. Box 6427, Providence, RI 02940-6427

TO ADD TO AN ACCOUNT

Fill out an investment slip, and write your account number on your check.
Indicate the year the contribution is for.

Mail in the slip and the check (see "To Open an Account" at left).

           By Telephone


WIRE  Have your bank send your investment to The Bank of New York, with these
instructions:

* ABA# 021000018

* DDA# 8900051973

* the fund name

* your account number

* name of investor

* the contribution year

ELECTRONIC CHECK  Same as wire, but insert "1111" before your account number.

TELEPHONE CONTRIBUTION  Call to request us to move money from a regular Dreyfus
account to an IRA (both accounts must be held in the same shareholder name).

           Automatically

   WITHOUT ANY INITIAL INVESTMENT  Call us
to request a Dreyfus Step Program form. Complete and return the form along with
your application.

ALL SERVICES  Call us to request a form to add an automatic investing service
(see "Services for Fund Investors"). Complete and return the form along with any
other required materials.

All contributions will count as current year.

           Via the Internet

   COMPUTER  Visit the Dreyfus Web site http://www.dreyfus.com and follow the
instructions to download an account application.







16

<PAGE 16>

TO SELL SHARES

Write a letter of instruction that includes:

* your name and signature

* your account number

* the fund name

* the dollar amount you want to sell

* how and where to send the proceeds

* whether the distribution is qualified or premature

* whether the 10% TEFRA should be withheld

Obtain a signature guarantee or other documentation, if required.

Mail in your request (see "To Open an Account" at left).


DREYFUS AUTOMATIC WITHDRAWAL PLAN  Call us to request instructions to establish
the plan.


  To reach Dreyfus, call toll free in the U.S.

  1-800-645-6561

  Outside the U.S. 516-794-5452

  Make checks payable to:

  THE DREYFUS TRUST COMPANY, CUSTODIAN

  You also can deliver requests to any Dreyfus Financial Center. Because
  processing time may vary, please ask the representative when your account will
  be credited or debited.

Concepts to understand

WIRE TRANSFER: for transferring money from one financial institution to another.
Wiring is the fastest way to move money, although your bank may charge a fee to
send or receive wire transfers. Wire redemptions from the fund are subject to a
$1,000 minimum.

ELECTRONIC CHECK: for transferring money out of a bank account. Your transaction
is entered electronically, but may take up to eight business days to clear.
Electronic checks usually are available without a fee at all Automated Clearing
House (ACH) banks.

                                                              Your Investment 17



<PAGE 17>

                    For More Information

                        Dreyfus GNMA Fund, Inc.
                        -----------------------------
                        SEC file number:  811-4215

                        More  information  on  this  fund is available free upon
                        request, including the following:

                        Annual/Semiannual Report

                        Describes   the  fund' s  performance,  lists  portfolio
                        holdings  and  contains a letter from the fund's manager
                        discussing recent market conditions, economic trends and
                        fund  strategies  that significantly affected the fund's
                        performance during the last fiscal year.

                        Statement of Additional Information (SAI)

                        Provides more details about the fund and its policies. A
                        current  SAI is on file with the Securities and Exchange
                        Commission  (SEC)  and  is incorporated by reference (is
                        legally considered part of this prospectus).

To obtain information:

BY TELEPHONE Call 1-800-645-6561

BY MAIL  Write to:
The Dreyfus Family of Funds
144 Glenn Curtiss Boulevard
Uniondale, NY 11556-0144

BY E-MAIL  Send your request to [email protected]

ON THE INTERNET  Text-only versions of certain fund documents can be viewed
online or downloaded from:

      SEC
      http://www.sec.gov

      DREYFUS
      http://www.dreyfus.com

You can also obtain copies by visiting the SEC's Public Reference Room in
Washington, DC (for information, call  1-202-942-8090) or, after paying a
duplicating fee, by E-mail request to [email protected], or by writing to the
SEC's Public Reference Section, Washington, DC 20549-0102.

(c) 2000 Dreyfus Service Corporation                                  265P1200



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