September 5, 2000
Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, NW
Washington, DC 20549
Re: Dreyfus GNMA Fund, Inc.
811-4215; 2-95553
Dear Sir/Madam:
Pursuant to Rule 497(j) under the Securities Act of 1933, this is to
certify that the form of Prospectus and Statement of Additional Information for
the above-referenced Fund does not differ from that contained in the most recent
amendment to the Fund's Registration Statement, electronically filed with the
Securities and Exchange Commission on August 28, 2000, pursuant to Rule 485(b).
Very truly yours,
/s/ John B. Hammalian
John B. Hammalian
Secretary
