BIOCRAFT LABORATORIES INC
DEFM14A, 1996-04-29
PHARMACEUTICAL PREPARATIONS
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<PAGE>
________________________________________________________________________________
________________________________________________________________________________
 
                            SCHEDULE 14A INFORMATION
 
              PROXY STATEMENT/PROSPECTUS PURSUANT TO SECTION 14(a)
                     OF THE SECURITIES EXCHANGE ACT OF 1934
 
Filed by the Registrant [x]
Filed by a party other than the Registrant [ ]
CHECK THE APPROPRIATE BOX:
 
[ ] Preliminary Proxy Statement
[ ] Confidential, for Use of the Commission Only (as permitted by Rule
14a-6(e)(2))
[x] Definitive Proxy Statement
[ ] Definitive Additional Materials
[ ] Soliciting Material Pursuant to SS 240.14a-11(c) or SS 240.14a-12
                            ------------------------
 
                          BIOCRAFT LABORATORIES, INC.
                (NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
 
    (NAME OF PERSON(S) FILING PROXY STATEMENT, IF OTHER THAN THE REGISTRANT)
 
                            ------------------------
 
Payment of Filing Fee (Check the appropriate box):
 
[ ] $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), 14a-6(i)(2) or Item
    22(a)(2) of Schedule 14A.
 
[ ] $500  per  each  party to  the  controversy  pursuant to  Exchange  Act Rule
    14a-6(i)(3).
 
[x] Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.
 
     1) Title of each class of  securities to which transaction applies:  COMMON
        STOCK, PAR VALUE $.01 PER SHARE OF BIOCRAFT LABORATORIES, INC.; AMERICAN
        DEPOSITARY SHARES OF TEVA PHARMACEUTICAL INDUSTRIES LIMITED ('TEVA').(1)
 
     2) Aggregate  number of securities to which transaction applies: 14,352,193
        SHARES OF COMMON STOCK OF BIOCRAFT; 6,616,361 AMERICAN DEPOSITARY SHARES
        OF TEVA
 
     3) Per unit  price  or  other  underlying  value  of  transaction  computed
        pursuant  to Exchange Act Rule  0-11 (set forth the  amount on which the
        filing fee is calculated and state  how it was determined): $38.875  PER
        AMERICAN DEPOSITARY SHARE OF TEVA(2)
 
     4) Proposed maximum aggregate value of transaction: $257,211,034(3)
 
     5) Total fee paid: $51,442.21
 
- ------------
 
(1) Each  American  Depositary  Share  ('ADS') of  Teva  represents  10 Ordinary
    Shares, par value NIS 0.01 each, of Teva.
 
(2) Based on the average of the high  and low prices of Teva's ADSs reported  on
    March  13, 1996 and the maximum number of ADSs of Teva issuable of 6,616,361
    ADSs.
 
(3) Estimated solely for purposes of calculating the filing fee.
                            ------------------------
 
[x] Fee paid previously with preliminary materials.
 
[ ] Check box if any part of the fee is offset as provided by Exchange Act  Rule
    0-11(a)(2)  and identify  the filing for  which the offsetting  fee was paid
    previously. Identify the previous  filing by registration statement  number,
    or the Form or Schedule and the date of its filing:
 
     1) Amount Previously Paid:  .............
 
     2) Form, Schedule or Registration Statement No.:  .............
 
     3) Filing Party:  .............
 
     4) Date Filed:  .............
 
________________________________________________________________________________
________________________________________________________________________________


<PAGE>
 
<PAGE>
                          BIOCRAFT LABORATORIES, INC.
                                18-01 RIVER ROAD
                          FAIR LAWN, NEW JERSEY 07410
 
Dear Stockholder:
 
     You  are cordially invited  to attend a Special  Meeting of Stockholders of
Biocraft Laboratories, Inc., which will be held at 10:00 a.m. on Friday, May 31,
1996, at the Marriott at Glenpointe, 100 Frank Burr Blvd., Teaneck, New Jersey.
 
     At the Special Meeting, holders of  Biocraft Common Stock will be asked  to
consider  a  proposal to  approve  and adopt  an  Agreement and  Plan  of Merger
providing for a merger in which  Biocraft will become a wholly owned  subsidiary
of Teva Pharmaceutical Industries Limited. Pursuant to the merger, each share of
Biocraft Common Stock will be converted into the right to receive 0.461 American
Depositary  Shares ('ADSs') of  Teva. Each ADS represents  10 Ordinary Shares of
Teva.
 
     The   proposed   merger   is   described   in   the   accompanying    Proxy
Statement/Prospectus,  the forepart of which includes  a summary of the terms of
the merger and certain other information relating to the proposed transaction. I
urge you  to review  carefully the  Proxy Statement/Prospectus  and the  Annexes
thereto.
 
     THE  BIOCRAFT BOARD OF DIRECTORS  HAS DETERMINED THAT THE  MERGER IS IN THE
BEST  INTERESTS  OF  BIOCRAFT  AND  ITS  STOCKHOLDERS.  ACCORDINGLY,  THE  BOARD
UNANIMOUSLY  APPROVED THE AGREEMENT AND PLAN  OF MERGER PROVIDING FOR THE MERGER
AND RECOMMENDS THAT THE HOLDERS  OF BIOCRAFT COMMON STOCK  VOTE IN FAVOR OF  THE
AGREEMENT AND PLAN OF MERGER AT THE MEETING.
 
     I  hope you will  attend the Special  Meeting. However, whether  or not you
plan to attend  the meeting,  please complete,  sign and  date the  accompanying
proxy  card promptly and return it in  the enclosed prepaid envelope. If you are
present at the meeting  you may, if  you wish, withdraw your  proxy and vote  in
person.
 
                                          HAROLD SNYDER
                                          Chairman, Chief Executive Officer
                                            and President
 
Fair Lawn, New Jersey
April 29, 1996
<PAGE>
 
<PAGE>
                          BIOCRAFT LABORATORIES, INC.
                                18-01 RIVER ROAD
                          FAIR LAWN, NEW JERSEY 07410
                            ------------------------
                   NOTICE OF SPECIAL MEETING OF STOCKHOLDERS
                                  MAY 31, 1996
                            ------------------------
 
To the Stockholders of
Biocraft Laboratories, Inc.:
 
     NOTICE IS HEREBY GIVEN that a Special Meeting of Stockholders (the 'Special
Meeting')  of Biocraft Laboratories, Inc.,  a Delaware corporation ('Biocraft'),
will be held on Friday, May 31,  1996, at the Marriott at Glenpointe, 100  Frank
Burr  Blvd., Teaneck, New Jersey, commencing at  10:00 a.m., local time, for the
following purposes:
 
          1. To  consider and  vote upon  a proposal  to approve  and adopt  the
     Agreement  and Plan of Merger (the  'Merger Agreement') dated as of January
     29, 1996, among Teva Pharmaceutical Industries Limited, a company organized
     under the laws of the State of Israel ('Teva'), Genco Merger Corporation, a
     Delaware corporation and a wholly owned subsidiary of Teva ('Merger  Sub'),
     and Biocraft, providing for the merger of Merger Sub with and into Biocraft
     (the 'Merger'). Pursuant to the Merger, Biocraft will become a wholly owned
     subsidiary  of Teva, and each outstanding  share of Common Stock, par value
     $.01 per share,  of Biocraft  ('Biocraft Common Stock')  will be  converted
     into  the right to receive 0.461  American Depositary Shares of Teva ('Teva
     ADSs'), each Teva ADS representing 10  Ordinary Shares, par value NIS  0.01
     each,  of Teva ('Teva Ordinary Shares'). A  copy of the Merger Agreement is
     attached as Annex I to the accompanying Proxy Statement/Prospectus.
 
          2. To transact  such other business  as may properly  come before  the
     Special Meeting or any adjournment or postponement thereof.
 
     The  Board of Directors has fixed the  close of business on April 22, 1996,
as the record date for the  determination of stockholders entitled to notice  of
and to vote at the Special Meeting and any adjournment or postponement thereof.
 
     The  affirmative vote of holders of two-thirds (66 2/3%) of the outstanding
shares of Biocraft  Common Stock is  necessary to approve  and adopt the  Merger
Agreement  providing for  the Merger.  The holders  of approximately  60% of the
outstanding shares of Biocraft Common  Stock have executed an irrevocable  proxy
appointing  Teva as agent to  vote such shares in  favor of the Merger Agreement
and the Merger. In accordance with the Delaware General Corporation Law, holders
of Biocraft Common  Stock are not  entitled to dissenters'  appraisal rights  in
connection with the Merger.
 
     Whether  or not  you plan  to attend the  Special Meeting,  please fill in,
sign, date  and  return the  enclosed  form of  proxy  card promptly.  A  return
envelope is enclosed for your convenience and requires no postage for mailing in
the United States.
 
                                          HAROLD SNYDER
                                          Chairman, Chief Executive Officer
                                            and President
 
Fair Lawn, New Jersey
April 29, 1996
 
                             YOUR VOTE IS IMPORTANT
 
           PLEASE DATE, SIGN AND COMPLETE THE ACCOMPANYING PROXY CARD
             AND MAIL IT PROMPTLY IN THE ENCLOSED RETURN ENVELOPE.


<PAGE>
 
<PAGE>
                          BIOCRAFT LABORATORIES, INC.
              PROXY STATEMENT FOR SPECIAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON MAY 31, 1996
                            ------------------------
                     TEVA PHARMACEUTICAL INDUSTRIES LIMITED
                                   PROSPECTUS
                                   FOR UP TO
                      6,616,361 AMERICAN DEPOSITARY SHARES
     REPRESENTING 66,163,610 ORDINARY SHARES, PAR VALUE NIS 0.01 PER SHARE
 
     This  Proxy  Statement/Prospectus  relates  to  the  proposed  merger  (the
'Merger') of Biocraft Laboratories,  Inc., a Delaware corporation  ('Biocraft'),
with  Genco  Merger Corporation,  a Delaware  corporation  ('Merger Sub')  and a
wholly owned subsidiary  of Teva  Pharmaceutical Industries  Limited, a  company
organized  under  the laws  of  the State  of  Israel ('Teva'),  pursuant  to an
Agreement and  Plan  of  Merger  dated  as of  January  29,  1996  (the  'Merger
Agreement').  As a  result of  the Merger, Biocraft  will become  a wholly owned
subsidiary of Teva. At the effective time of the Merger (the 'Effective  Time'),
each  outstanding share of Common  Stock, par value $.01  per share, of Biocraft
('Biocraft Common Stock')  will be  converted into  the right  to receive  0.461
American  Depositary Shares of Teva ('Teva ADSs'), each Teva ADS representing 10
Ordinary Shares, par value New Israeli  Shekels ('NIS') 0.01 per share, of  Teva
('Teva  Ordinary Shares'). Biocraft is  soliciting proxies from its stockholders
for use at the Special Meeting of Stockholders of Biocraft scheduled to be  held
on  Friday, May 31,  1996 (the 'Special  Meeting') to consider  the approval and
adoption of  the  Merger Agreement  providing  for  the Merger.  The  Merger  is
expected  to  be consummated  immediately after  approval of  the Merger  by the
stockholders of Biocraft.
 
     This Proxy  Statement/Prospectus constitutes  both the  proxy statement  of
Biocraft  relating to the solicitation of proxies  by its Board of Directors for
use at the Special Meeting and the  prospectus of Teva with respect to the  Teva
Ordinary  Shares represented by Teva ADSs to be issued in the Merger in exchange
for outstanding shares of Biocraft Common Stock. This Proxy Statement/Prospectus
and the enclosed forms of proxy are first being sent to stockholders of Biocraft
on or about May 2, 1996.
 
     SEE 'RISK  FACTORS'  ON  PAGE  16 FOR  A  DESCRIPTION  OF  CERTAIN  FACTORS
CONCERNING TEVA AND ITS OPERATIONS FOLLOWING THE MERGER.
                            ------------------------
THE SECURITIES TO WHICH THIS PROXY STATEMENT/PROSPECTUS RELATES HAVE NOT BEEN
   APPROVED OR DISAPPROVED BY THE SECURITIES AND EXCHANGE COMMISSION OR ANY
     STATE  SECURITIES COMMISSION,  NOR HAS  THE SECURITIES  AND EXCHANGE
       COMMISSION OR  ANY STATE  SECURITIES COMMISSION  PASSED UPON  THE
        ACCURACY  OR ADEQUACY OF  THIS PROXY STATEMENT/PROSPECTUS. ANY
               REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                            ------------------------
THE SECURITIES AUTHORITY OF  THE STATE OF ISRAEL  HAS EXEMPTED TEVA FROM  THE
   REQUIREMENT UNDER ISRAELI LAW TO OBTAIN A PERMIT TO PUBLISH THE PROSPECTUS
     IN  CONNECTION WITH THE OFFERING HEREUNDER. NOTHING IN THE EXEMPTION
       GRANTED SHALL BE CONSTRUED AS AN EXPRESSION OF OPINION AS TO  THE
                   QUALITY OF THE SECURITIES OFFERED HEREBY.
 
                            ------------------------
A  COPY OF THIS PROXY STATEMENT/PROSPECTUS WILL BE FILED WITH THE REGISTRAR OF
  COMPANIES AND THE SECURITIES AUTHORITY OF THE STATE OF ISRAEL. ALL PERMITS,
     APPROVALS AND LICENSES REQUIRED UNDER THE LAWS OF THE STATE OF  ISRAEL
     FOR THE OFFERING OF THE TEVA ORDINARY SHARES AND FOR THE PUBLICATION
             OF THIS PROXY STATEMENT/PROSPECTUS HAVE BEEN OBTAINED.
 
                            ------------------------
 
         The date of this Proxy Statement/Prospectus is April 29, 1996.
 
<PAGE>
 
<PAGE>
     NO  PERSON  HAS BEEN  AUTHORIZED TO  GIVE  ANY INFORMATION  OR TO  MAKE ANY
REPRESENTATION, OTHER THAN THOSE  CONTAINED IN THIS PROXY  STATEMENT/PROSPECTUS,
IN  CONNECTION  WITH  THE  SOLICITATION  AND THE  OFFERING  MADE  BY  THIS PROXY
STATEMENT/PROSPECTUS AND, IF GIVEN OR  MADE, SUCH INFORMATION OR  REPRESENTATION
SHOULD   NOT   BE   RELIED  UPON   AS   HAVING  BEEN   AUTHORIZED.   THIS  PROXY
STATEMENT/PROSPECTUS DOES NOT CONSTITUTE THE SOLICITATION OF A PROXY OR AN OFFER
TO SELL,  OR A  SOLICITATION OF  AN OFFER  TO PURCHASE,  ANY SECURITIES  IN  ANY
JURISDICTION IN WHICH SUCH SOLICITATION OR OFFERING MAY NOT LAWFULLY BE MADE.
 
     NEITHER   THE  DELIVERY   OF  THIS   PROXY  STATEMENT/PROSPECTUS   NOR  ANY
DISTRIBUTION OF SECURITIES  MADE HEREUNDER SHALL  IMPLY THAT THERE  HAS BEEN  NO
CHANGE IN THE INFORMATION SET FORTH HEREIN OR IN THE AFFAIRS OF TEVA OR BIOCRAFT
SINCE  THE DATE HEREOF OR THAT THE INFORMATION  HEREIN IS CORRECT AS OF ANY TIME
SUBSEQUENT TO ITS DATE.
 
                            ------------------------
 
                             AVAILABLE INFORMATION
 
     Biocraft is subject  to the  informational requirements  of the  Securities
Exchange  Act  of  1934 (the  'Exchange  Act'),  and Teva  is  subject  to those
informational requirements of the  Exchange Act that  are applicable to  foreign
private  issuers. In  accordance with the  Exchange Act, Teva  and Biocraft file
reports and other information with  the Securities and Exchange Commission  (the
'SEC'). Biocraft also files proxies with the SEC in accordance with the Exchange
Act.  Teva is not subject  to the SEC's proxy  requirements. This filed material
can be inspected and copied at the public reference facilities maintained by the
SEC at Room  1024, 450  Fifth Street,  N.W., Washington,  DC 20549,  and at  the
following  Regional Offices  of the  SEC: Chicago  Regional Office  (Suite 1400,
Citicorp Center, 500 West Madison Street, Chicago, Illinois 60661) and New  York
Regional  Office  (Seven World  Trade  Center, 13th  Floor,  New York,  New York
10048). Copies  of  such  material can  be  obtained  by mail  from  the  Public
Reference  Section of the SEC, 450 Fifth  Street, N.W., Washington, DC 20549, at
prescribed rates. In addition,  such material for Teva  can be inspected at  the
offices  of the National  Association of Securities  Dealers, Inc. (the 'NASD'),
1735 K Street,  N.W., Washington, DC  20006. Such material  for Biocraft can  be
inspected  at the offices of the New  York Stock Exchange, Inc. (the 'NYSE'), 20
Broad Street, New York, New York 10005.
 
     Teva has  filed a  Registration Statement  on Form  F-4 (the  'Registration
Statement')  with the  SEC under  the Securities  Act of  1933, as  amended (the
'Securities Act') with respect to the Teva Ordinary Shares, represented by  Teva
ADSs,   to   be   issued   upon  consummation   of   the   Merger.   This  Proxy
Statement/Prospectus does  not contain  all  the information  set forth  in  the
Registration  Statement and the exhibits thereto, certain portions of which have
been omitted as permitted by the rules and regulations of the SEC. Copies of the
Registration Statement (including such omitted portions) are available from  the
SEC upon payment of prescribed rates. For further information, reference is made
to  the  Registration Statement  and  the exhibits  filed  therewith. Statements
contained in this Proxy Statement/Prospectus or in any document incorporated  by
reference  in this  Proxy Statement/Prospectus relating  to the  contents of any
contract or other  document referred to  herein or therein  are not  necessarily
complete, and in each instance reference is made to the copy of such contract or
other  document filed as an exhibit to  the Registration Statement or such other
document, each such statement being qualified in all respects by such reference.
 
     Teva is currently exempt from the rules under the Exchange Act  prescribing
the  furnishing and content of proxy statements, and its officers, directors and
principal shareholders  are exempt  from the  reporting and  short-swing  profit
recovery  provisions contained in Section  16 of such Act.  Teva is not required
under the  Exchange Act  to publish  financial statements  as frequently  or  as
promptly  as are  United States companies  subject thereto.  Teva will, however,
continue to  furnish its  shareholders with  annual reports  containing  audited
financial  statements  and  quarterly reports  containing  unaudited  results of
operations as well as such other reports as may from time to time be  authorized
by Teva's Board of Directors or be required under law.
 
                                       2
 
<PAGE>
 
<PAGE>
     Teva  prepares  its consolidated  financial  statements in  accordance with
accounting principles  generally  accepted in  Israel  ('Israel GAAP')  and  the
United  States ('U.S. GAAP'). As applicable to Teva's financial statements, such
accounting principles are practically identical, except as described in Note  12
of  Notes to Consolidated Financial Statements contained in Teva's Annual Report
on Form 20-F for the fiscal year ended December 31, 1995.
 
                INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
 
     The following Teva documents  are incorporated by  reference in this  Proxy
Statement/Prospectus:
 
          (a)  Annual Report on Form  20-F for the year  ended December 31, 1995
     (File No. 0-16174); and
 
          (b) Reports of Foreign Issuer on Form 6-K pursuant to Rules 13a-16 and
     15d-16, filed with the  SEC on January 4,  1996, January 11, 1996,  January
     18,  1996, January 30, 1996, March 4,  1996, March 5, 1996, March 15, 1996,
     April 2, 1996, April 15, 1996, April 17, 1996 and April 19, 1996.
 
     The following  Biocraft documents  are incorporated  by reference  in  this
Proxy Statement/Prospectus:
 
          (a) Annual Report on Form 10-K for the year ended March 31, 1995 (File
     No.  1-8867), as amended by  Form 10-K/A-1 filed with  the SEC on April 29,
     1996; and
 
          (b) Quarterly Reports  on Form  10-Q for  the periods  ended June  30,
     1995, September 30, 1995 and December 31, 1995.
 
     All  reports and definitive  proxy or information  statements filed by Teva
and Biocraft pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act
subsequent to the date of this Proxy Statement/Prospectus and prior to the  date
of the Special Meeting shall be deemed to be incorporated by reference into this
Proxy  Statement/Prospectus  from the  dates of  filing  of such  documents. Any
statement contained in a document incorporated  or deemed to be incorporated  in
this Proxy Statement/Prospectus shall be deemed to be modified or superseded for
purposes  of  this Proxy  Statement/Prospectus to  the  extent that  a statement
contained herein or in any other subsequently filed document that also is or  is
deemed  to be incorporated  by reference modifies  or supersedes such statement.
Any such statement so modified or superseded  shall not be deemed, except as  so
modified or superseded, to constitute a part of this Proxy Statement/Prospectus.
All  information appearing in this Proxy Statement/Prospectus or in any document
incorporated herein by reference is not necessarily complete and is qualified in
its entirety  by  the  information and  financial  statements  (including  notes
thereto)  appearing in the documents incorporated by reference herein and should
be read together with such information and documents.
 
     All information contained  in this Proxy  Statement/Prospectus relating  to
Teva  or Merger Sub has  been supplied by Teva,  and all information relating to
Biocraft has been supplied by Biocraft.
 
     THIS PROXY STATEMENT/PROSPECTUS INCORPORATES  DOCUMENTS BY REFERENCE  WHICH
ARE  NOT PRESENTED  HEREIN OR DELIVERED  HEREWITH. COPIES OF  ANY SUCH DOCUMENTS
(EXCLUDING EXHIBITS  TO SUCH  DOCUMENTS UNLESS  SUCH EXHIBITS  ARE  SPECIFICALLY
INCORPORATED   BY  REFERENCE  INTO  THE  INFORMATION  INCORPORATED  HEREIN)  ARE
AVAILABLE WITHOUT CHARGE TO ANY PERSON, INCLUDING ANY BENEFICIAL OWNER, TO  WHOM
THIS  PROXY STATEMENT/PROSPECTUS IS DELIVERED UPON ORAL OR WRITTEN REQUEST. WITH
RESPECT TO TEVA'S DOCUMENTS, REQUESTS SHOULD BE DIRECTED TO 5 BASEL STREET, P.O.
BOX  3190,   PETACH  TIKVA   49131  ISRAEL,   ATTN:  UZI   KARNIEL   (TELEPHONE:
011-972-3-9267267).  WITH RESPECT  TO BIOCRAFT'S  DOCUMENTS, REQUESTS  SHOULD BE
DIRECTED TO 18-01 RIVER ROAD, FAIR LAWN, NEW JERSEY 07410, ATTN: ETHYL  ANDERSEN
(TELEPHONE:  (201)  703-0400).  IN  ORDER  TO  ENSURE  TIMELY  DELIVERY  OF SUCH
DOCUMENTS, ANY REQUEST SHOULD BE MADE BY MAY 24, 1996.
 
                                       3
 
<PAGE>
 
<PAGE>
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                                                                                              PAGE
                                                                                                              ----
<S>                                                                                                           <C>
SUMMARY....................................................................................................     7
     Special Meeting.......................................................................................     7
     Votes Required........................................................................................     7
     The Merger............................................................................................     7
     Irrevocable Proxy and Termination Rights Agreement....................................................    11
     Regulatory Matters....................................................................................    11
     Certain Tax Consequences of the Merger................................................................    11
     Anticipated Accounting Treatment......................................................................    12
     Absence of Appraisal Rights...........................................................................    12
     Market Price Data.....................................................................................    12
     Certain Significant Considerations....................................................................    12
     Teva and Biocraft Selected Historical and Pro Forma Combined Financial Data...........................    13
     Comparative Per ADS and Per Share Data................................................................    15
RISK FACTORS...............................................................................................    16
     Fixed Exchange Ratio..................................................................................    16
     Difficulty of Integration of Operations Following the Merger..........................................    16
     Regulatory Status of Copaxone'r'......................................................................    16
     Biocraft's History of Regulatory Problems.............................................................    16
     Dependency on Product Development.....................................................................    17
     Competition and Technological Change..................................................................    17
     Government Regulation.................................................................................    18
     Product Liability.....................................................................................    18
     Pharmaceutical Pricing and Health Care Reform.........................................................    18
     Legal Proceedings.....................................................................................    19
     Foreign Operations....................................................................................    19
     Risk of More Limited Information from Foreign Private Issuer..........................................    19
     Service and Enforcement of Legal Process..............................................................    19
THE SPECIAL MEETING........................................................................................    20
     Special Meeting.......................................................................................    20
     Record Date; Shares Entitled to Vote..................................................................    21
     Vote Required and Irrevocable Proxy...................................................................    21
     Proxies; Proxy Solicitation...........................................................................    21
     Miscellaneous.........................................................................................    22
THE MERGER.................................................................................................    22
     Background of the Merger..............................................................................    22
     Recommendation of the Biocraft Board and Biocraft's Reasons for the Merger............................    23
     Certain Advantages and Disadvantages of the Merger to Biocraft and its Stockholders...................    24
     Teva's Reasons for the Merger.........................................................................    24
     Opinion of Financial Advisor..........................................................................    25
     Effective Time........................................................................................    28
     Exchange Ratio........................................................................................    28
     Exchange Agent; Exchange Procedures; Distributions with Respect to Unexchanged Shares; No Further
      Ownership Rights in Biocraft Common Stock; No Fractional Teva ADSs...................................    28
     Admission for Trading on NASDAQ National Market.......................................................    30
     Cessation of NYSE Trading and Deregistration of Biocraft Common Stock After the Merger................    30
     Certain Significant Considerations....................................................................    30
     Certain Tax Consequences of the Merger................................................................    30
     Anticipated Accounting Treatment......................................................................    31
     Absence of Appraisal Rights...........................................................................    31
     Irrevocable Proxy and Termination Rights Agreement....................................................    31
</TABLE>
 
                                       4
 
<PAGE>
 
<PAGE>
 
<TABLE>
<CAPTION>
                                                                                                              PAGE
                                                                                                              ----
<S>                                                                                                           <C>
     Interests of Certain Persons in the Merger............................................................    32
     Operations After the Merger...........................................................................    33
     Effect on Dividend Reinvestment Plan..................................................................    33
     Severance Payments; Effect on Employee Benefit and Stock Option Plans; Indemnification................    34
     Regulatory Filings and Approvals......................................................................    35
     Resale of Teva ADSs...................................................................................    36
     Right of the Biocraft Board to Withdraw Recommendation................................................    36
DESCRIPTION OF TEVA........................................................................................    37
DESCRIPTION OF BIOCRAFT....................................................................................    37
COMPARATIVE STOCK PRICES AND DIVIDENDS.....................................................................    38
     Teva ADSs.............................................................................................    38
     Teva Ordinary Shares..................................................................................    39
     Dividends on Teva Ordinary Shares.....................................................................    39
     Biocraft Common Stock.................................................................................    40
     Dividends on Biocraft Common Stock....................................................................    41
UNAUDITED PRO FORMA COMBINED CONDENSED FINANCIAL STATEMENTS................................................    42
TERMS OF THE MERGER AGREEMENT..............................................................................    48
     The Merger; Exchange and Conversion of Shares.........................................................    48
     Exchange of Share Certificates........................................................................    48
     Treatment of Biocraft Stock Options...................................................................    49
     Effective Time........................................................................................    49
     Termination Rights....................................................................................    50
     Certain Fees and Expenses.............................................................................    50
     Conditions to the Merger..............................................................................    51
     Representations and Warranties........................................................................    53
     Indemnification; Officers' and Directors' Liability Insurance.........................................    53
     Certain Covenants of Biocraft.........................................................................    53
     Certain Covenants of Teva.............................................................................    54
     No Solicitation of Other Offers.......................................................................    55
     Amendments............................................................................................    55
DESCRIPTION OF TEVA ORDINARY SHARES........................................................................    56
DESCRIPTION OF AMERICAN DEPOSITARY SHARES..................................................................    56
     American Depositary Receipts..........................................................................    56
     Deposit and Withdrawal of Teva Ordinary Shares........................................................    56
     Dividends, Other Distributions and Rights.............................................................    57
     Record Dates..........................................................................................    59
     Reports and Other Communications......................................................................    59
     Voting of the Underlying Teva Ordinary Shares.........................................................    59
     Amendment and Termination of the Deposit Agreement....................................................    60
     Charges of Depositary.................................................................................    60
     Liability of Holders for Taxes, Duties or Other Charges...............................................    61
     Transfer of American Depositary Receipts..............................................................    61
     General...............................................................................................    61
COMPARISON OF STOCKHOLDER RIGHTS...........................................................................    62
     Vote Required for Certain Actions.....................................................................    62
     Appraisal Rights......................................................................................    62
     Stockholders' Meeting.................................................................................    63
     Action by Written Consent of Stockholders.............................................................    63
     Election of Directors; Classes of Directors; Cumulative Voting........................................    63
     Newly Created Directorships and Vacancies.............................................................    64
     Removal of Directors..................................................................................    64
     Dividends.............................................................................................    65
</TABLE>
 
                                       5
 
<PAGE>
 
<PAGE>
 
<TABLE>
<CAPTION>
                                                                                                              PAGE
                                                                                                              ----
<S>                                                                                                           <C>
     Treasury Shares.......................................................................................    65
     Business Combinations.................................................................................    65
     Limitation on Directors' Liability; Indemnification of Officers and Directors.........................    66
     Loans to Directors and Officers.......................................................................    66
     Special Meetings......................................................................................    66
     Warrants or Options...................................................................................    67
     Stockholder Suits.....................................................................................    67
     Registration of Shares in Name of Pledgee.............................................................    67
     Inspection of Corporate Books and Records; Shareholder Lists..........................................    67
SECURITY OWNERSHIP OF DIRECTORS, EXECUTIVE OFFICERS AND OWNERS OF 5% OR MORE OF BIOCRAFT COMMON STOCK......    68
EXPERTS....................................................................................................    69
LEGAL MATTERS..............................................................................................    69
ANNEX I -- Agreement and Plan of Merger
ANNEX II -- Opinion of Goldman, Sachs & Co.
</TABLE>
 
                                       6


<PAGE>
 
<PAGE>
                                    SUMMARY
 
     The  following is a  summary of certain  information contained elsewhere in
this Proxy  Statement/Prospectus. Reference  is  made to,  and this  summary  is
qualified  in its entirety by, the more detailed information contained elsewhere
in this Proxy Statement/Prospectus, in the attached Annexes and in the documents
incorporated herein by reference. Stockholders are urged to read carefully  this
Proxy Statement/Prospectus and the attached Annexes in their entirety.
 
     This  Proxy  Statement/Prospectus  relates  to  the  proposed  merger  (the
'Merger') of Biocraft Laboratories,  Inc., a Delaware corporation  ('Biocraft'),
with  Genco  Merger Corporation,  a Delaware  corporation  ('Merger Sub')  and a
wholly owned subsidiary  of Teva  Pharmaceutical Industries  Limited, a  company
organized  under  the laws  of  the State  of  Israel ('Teva'),  pursuant  to an
Agreement and  Plan  of  Merger  dated  as of  January  29,  1996  (the  'Merger
Agreement').  As a  result of  the Merger, Biocraft  will become  a wholly owned
subsidiary of Teva. At the effective time of the Merger (the 'Effective  Time'),
each  outstanding share of Common  Stock, par value $.01  per share, of Biocraft
(the 'Biocraft Common Stock') will be converted into the right to receive  0.461
American  Depositary Shares of Teva ('Teva ADSs'), each Teva ADS representing 10
Ordinary Shares, par value NIS 0.01 per share, of Teva ('Teva Ordinary Shares').
Teva ADSs are represented by American Depositary Receipts ('ADRs'). The exchange
ratio of 0.461 Teva ADSs for each  share of Biocraft Common Stock, as set  forth
in the Merger Agreement, is hereinafter referred to as the 'Exchange Ratio'.
 
SPECIAL MEETING
 
     A  Special Meeting of  the stockholders of  Biocraft will be  held at 10:00
a.m., local  time, on  Friday, May  31,  1996 (the  'Special Meeting'),  at  the
Marriott  at Glenpointe, 100 Frank Burr Blvd., Teaneck, New Jersey. Only holders
of record of Biocraft Common Stock at the close of business on Monday, April 22,
1996 (the 'Record Date'),  will be entitled  to notice of, and  to vote at,  the
Special  Meeting. At the Special Meeting,  holders of Biocraft Common Stock will
be asked to consider and vote upon the approval of the Merger Agreement, a  copy
of  which is attached as Annex I to this Proxy Statement/Prospectus, pursuant to
which Merger Sub will  be merged with  and into Biocraft.  Biocraft will be  the
surviving  corporation  in the  Merger  (the 'Surviving  Corporation')  and will
become a wholly owned subsidiary of Teva. Holders of Biocraft Common Stock  will
also  transact  such other  business  as may  properly  come before  the Special
Meeting.
 
VOTES REQUIRED
 
     The affirmative  vote  of  the  holders of  two-thirds  (66  2/3%)  of  the
outstanding  shares of Biocraft Common Stock is required for the approval of the
Merger Agreement. As an inducement for Teva to enter into the Merger  Agreement,
Harold   Snyder,  Biocraft's  current  Chairman,  Chief  Executive  Officer  and
President,  Beatrice  Snyder,  Biocraft's  current  Senior  Vice  President  and
Secretary,  and their children as trustees for certain trusts which Mr. and Mrs.
Snyder have  established, holding  in  the aggregate  approximately 60%  of  the
outstanding  Biocraft  Common  Stock,  have executed  an  Irrevocable  Proxy and
Termination Rights Agreement  (the 'Irrevocable Proxy')  pursuant to which  such
stockholders  have,  among  other  things, appointed  Teva  their  lawful agent,
attorney and proxy to vote such shares of Biocraft Common Stock in favor of  the
Merger  Agreement  and the  Merger.  See 'THE  MERGER  -- Irrevocable  Proxy and
Termination Rights  Agreement' and  'THE SPECIAL  MEETING --  Vote Required  and
Irrevocable Proxy'.
 
     The  approval of  the shareholders  of Teva is  not required  to effect the
Merger.
 
THE MERGER
 
     The Parties.  Teva  develops,  manufactures and  markets  branded,  generic
(off-patent) and branded generic pharmaceutical products. Teva also manufactures
and sells bulk pharmaceutical chemicals, hospital supplies, veterinary products,
yeast  and alcohol. Teva is the leading  supplier of such products in Israel and
has manufacturing facilities in Israel, Europe  and the United States. Over  60%
of its sales are generated outside of Israel. The principal executive offices of
Teva  are located at  5 Basel Street,  Petach Tikva 49131  Israel. The telephone
number is 011-972-3-9267267.
 
                                       7
 
<PAGE>
 
<PAGE>
     Merger Sub, a Delaware  corporation, is a wholly  owned subsidiary of  Teva
formed solely for the purpose of effecting the Merger.
 
     Biocraft  develops, manufactures  and markets  generic drugs  in the United
States. Its facilities are located in  Northern New Jersey and in Missouri.  The
principal  executive offices of  Biocraft are located at  18-01 River Road, Fair
Lawn, New Jersey 07410. The telephone number is (201) 703-0400.
 
     Exchange Ratio. At the Effective  Time, each outstanding share of  Biocraft
Common  Stock, other than treasury  shares, will be converted  into the right to
receive 0.461 Teva ADSs, each Teva ADS representing 10 Teva Ordinary Shares.  No
fractional  Teva ADSs will be issued in the  Merger and the holders of shares of
Biocraft Common Stock will  be entitled to  a cash payment in  lieu of any  such
fractional Teva ADSs which would otherwise be issued in the Merger.
 
     Recommendation  of the Biocraft  Board and Reasons  for the Merger; Certain
Advantages and Disadvantages.  THE BIOCRAFT  BOARD HAS  UNANIMOUSLY ADOPTED  THE
MERGER  AGREEMENT,  DETERMINED  THAT THE  MERGER  IS  IN THE  BEST  INTERESTS OF
BIOCRAFT AND ITS STOCKHOLDERS AND  RECOMMENDS THAT THE STOCKHOLDERS OF  BIOCRAFT
VOTE FOR THE APPROVAL OF THE MERGER AGREEMENT. In reaching its decision to adopt
the  Merger Agreement and recommend the  Merger, the Biocraft Board considered a
number  of  factors.  See  'THE  MERGER   --  Background  of  the  Merger'   and
'  --  Recommendation  of the  Biocraft  Board  and Biocraft's  Reasons  for the
Merger'. See also  'THE MERGER --  Certain Advantages and  Disadvantages of  the
Merger  to Biocraft and  its Stockholders' for  a summary of  certain actual and
potential advantages and disadvantages of the Merger.
 
     Opinion of  Financial  Advisor.  Goldman, Sachs  &  Co.  ('Goldman  Sachs')
delivered  its oral  opinion on January  28, 1996  to the Board  of Directors of
Biocraft that the Exchange Ratio pursuant to  the Merger is fair to the  holders
of  Biocraft Common Stock. Goldman Sachs  confirmed its oral opinion by delivery
of its  written opinion  dated  January 29,  1996.  In addition,  Goldman  Sachs
subsequently  confirmed its earlier opinion  by  delivery of its written opinion
dated as of the  date hereof. The  full text of the  written opinion of  Goldman
Sachs  dated as of the  date hereof, which sets  forth assumptions made, matters
considered and  limitations on  the  review undertaken  in connection  with  the
opinion,  is  attached as  Annex II  to this  Proxy Statement/Prospectus  and is
incorporated herein by reference. HOLDERS OF BIOCRAFT COMMON STOCK ARE URGED TO,
AND SHOULD, READ SUCH  OPINION IN ITS  ENTIRETY. See 'THE  MERGER -- Opinion  of
Financial Advisor'.
 
     Interests  of  Certain  Persons  in  the Merger.  As  of  the  Record Date,
directors and  executive officers  of Biocraft  and their  affiliates owned  (i)
9,104,884  shares of Biocraft Common Stock (for which they will receive the same
consideration as  other  Biocraft  stockholders) and  (ii)  options  to  acquire
117,400  shares of Biocraft Common Stock, which will be treated in the Merger as
described below  under 'THE  MERGER --  Severance Payments;  Effect on  Employee
Benefit  and Stock Option Plans'. In addition, Harold Snyder, Biocraft's current
Chairman, President and Chief Executive Officer, and Beatrice Snyder, Biocraft's
current Senior  Vice President  and Secretary,  are expected  to be  parties  to
employment  agreements with  the Surviving  Corporation pursuant  to which their
employment with  the  Surviving Corporation  shall  continue and  their  current
compensation  and other benefits will continue  to be provided to them following
the Effective  Time. Pursuant  to such  employment agreements,  Mr. Snyder  will
serve   as  Senior   Vice  President  and   Mrs.  Snyder  will   serve  as  Vice
President -  Cost  Accounting  and  Inventory and  Secretary  of  the  Surviving
Corporation.  In addition, Mr. Snyder  and Mrs. Snyder will  be nominated at the
next annual meeting of Teva shareholders to serve on Teva's Board of  Directors.
Mr.  Snyder is also  expected to be  designated as a  member of Teva's executive
committee. See 'THE MERGER -- Interests  of Certain Persons in the Merger'.  The
Merger  Agreement also provides for the payment of certain severance benefits to
executive officers  and employees  of  Biocraft. See  'THE MERGER  --  Severance
Payments;    Effect   on    Employee   Benefit    and   Stock    Option   Plans;
Indemnification -- Severance Payments'.
 
     Security Ownership  of  Certain Persons;  Irrevocable  Proxies. As  of  the
Record  Date, there were 14,184,843 shares of Biocraft Common Stock outstanding,
of which  9,104,884 shares  (approximately 64.2%  of the  outstanding shares  of
Biocraft  Common  Stock)  were  beneficially owned  by  directors  and executive
officers of Biocraft and their affiliates. See 'SECURITY OWNERSHIP OF DIRECTORS,
EXECUTIVE  OFFICERS   AND   OWNERS   OF   5%  OR   MORE   OF   BIOCRAFT   COMMON
 
                                       8
 
<PAGE>
 
<PAGE>
STOCK'.  All such  directors and  executive officers  and their  affiliates have
indicated to Biocraft that they  intend to vote or direct  the vote of all  such
shares in favor of the approval of the Merger Agreement. In addition, Harold and
Beatrice  Snyder and their children as trustees for certain trusts which Mr. and
Mrs. Snyder have established, holding in the aggregate approximately 60% of  the
outstanding  shares of Biocraft Common Stock, have appointed Teva as irrevocable
proxy to vote their shares in favor of approval of the Merger Agreement and  the
Merger.
 
     Dividend  Reinvestment Plan. Biocraft  has amended, pursuant  to the Merger
Agreement, the  Stockholder Dividend  Reinvestment and  Stock Purchase  Plan  to
terminate  the supplemental  payment investment option  offered thereunder. Teva
does not have a comparable plan; accordingly, no dividend reinvestment plan will
be available following the Merger to former holders of Biocraft Common Stock.
 
     Stock Option  Plans.  Pursuant  to  the  Merger  Agreement,  prior  to  the
Effective  Time the Biocraft  Board will terminate  the Biocraft Incentive Stock
Option Plan and the 1987 Directors' Stock Option Plan and each holder of options
under such  plans will,  in  accordance with  the terms  of  his or  her  option
agreements,  have the  right to exercise,  by written notice,  all such options,
whether or not then exercisable by the terms of the applicable option agreement.
Options as to which no  notice of exercise is  received by Biocraft (other  than
options  held by executive  officers or directors  subject to Section  16 of the
Exchange Act) will  be converted into  the right to  receive promptly after  the
Effective  Time,  as to  each  share of  Biocraft  Common Stock  covered thereby
(without regard to  any then  applicable restrictions  on the  exercise of  such
options),  the number  of Teva ADSs  determined by (i)  multiplying the Exchange
Ratio by  the fair  market value  of  a Teva  ADS on  the Effective  Date,  (ii)
subtracting  from the product  of such multiplication the  sum of the applicable
per share exercise price plus applicable per share withholding for taxes  (which
will be appropriately remitted to the applicable tax authority on behalf of such
optionee)  and (iii)  dividing the  amount obtained in  clause (ii)  by the fair
market value of a  Teva ADS on  the Effective Date. For  such purpose, the  fair
market  value of a Teva ADS on the NASDAQ National Market shall mean the average
of the last sale prices of a Teva  ADS on the NASDAQ National Market on each  of
the  ten trading days  ending two trading  days prior to  the Effective Date. In
addition, prior to the Effective Time,  but subject to the Merger, the  Biocraft
Board  will cause Biocraft's Restricted Stock Purchase Plan to be amended to (a)
provide that no further restricted stock grants be made after the Effective Time
and (b) provide that  the terms and  conditions of such Plan  will apply to  the
Teva  Ordinary Shares and  the Teva ADSs representing  such Teva Ordinary Shares
issued upon the Merger to the holders  of restricted stock under such Plan,  and
such  holders  shall thereafter  hold such  Teva ADSs  and Teva  Ordinary Shares
subject to the terms and conditions  of such Plan, including without  limitation
any requirement for the legending of certificates evidencing such securities.
 
     Conditions  to the Merger. The obligations of Teva, Merger Sub and Biocraft
to consummate the Merger  are subject to the  satisfaction or waiver of  various
conditions,   including,  without  limitation,  obtaining  Biocraft  stockholder
approval and admission for trading (subject  to official notice of issuance)  on
the NASDAQ National Market of the Teva ADSs representing Teva Ordinary Shares to
be   issued  in   connection  with  the   Merger.  See  'TERMS   OF  THE  MERGER
AGREEMENT -- Conditions to the Merger'.
 
     No Solicitation. The Merger Agreement  provides that Biocraft may not,  nor
may  it permit any of its subsidiaries to, nor may it authorize or permit any of
its officers or directors or any investment banker, attorney or other advisor or
representative retained  by  it or  any  of  its subsidiaries  to,  directly  or
indirectly,  (i) solicit, initiate  or encourage the  submission of any Takeover
Proposal (as  defined  therein),  or  (ii) participate  in  any  discussions  or
negotiations  regarding, or furnish  to any person  any information with respect
to, or take any other  action to facilitate any inquiries  or the making of  any
proposal  that  constitutes,  or may  reasonably  be  expected to  lead  to, any
Takeover Proposal. However, to the extent required by the fiduciary  obligations
of  the Biocraft Board (as determined in  good faith by the Biocraft Board after
reviewing the  advice of  outside  counsel), Biocraft  may,  in response  to  an
unsolicited   Takeover  Proposal  and  subject  to  compliance  with  Biocraft's
responsibility to keep Teva informed in all material respects of the status  and
details  of any such Takeover Proposal and certain other conditions, (a) furnish
and discuss information  with respect to  Biocraft to any  person pursuant to  a
customary
 
                                       9
 
<PAGE>
 
<PAGE>
confidentiality  agreement (as  determined by  Biocraft's outside  counsel) with
such person and (b) participate  in negotiations and discussions regarding  such
Takeover  Proposal. See  'TERMS OF  THE MERGER  AGREEMENT --  No Solicitation of
Other Offers'.
 
     Right of the Biocraft  Board to Withdraw  Recommendation. Under the  Merger
Agreement,  the Biocraft Board or any committee  thereof may not (i) withdraw or
modify, or propose to withdraw or modify, in a manner adverse to Teva or  Merger
Sub,  the Biocraft Board's approval or recommendation of the Merger Agreement or
the Merger, (ii) approve or recommend,  or propose to approve or recommend,  any
Takeover Proposal or (iii) enter into any agreement with respect to any Takeover
Proposal.  Notwithstanding  the  foregoing,  if the  Biocraft  Board  receives a
Takeover Proposal  that,  in  the  exercise of  its  fiduciary  obligations  (as
determined  in good faith by  the Biocraft Board, after  reviewing the advice of
outside counsel), it determines to be Superior Proposal, the Biocraft Board  may
(a) withdraw or modify its approval or recommendation of the Merger Agreement or
the  Merger, (b) approve or  recommend any Superior Proposal  (as defined in the
Merger Agreement), (c)  enter into an  agreement with respect  to such  Superior
Proposal  or (d) terminate the Merger Agreement,  in each case at any time after
the second business day following Teva's receipt of written notice advising Teva
that the  Biocraft  Board  has  received a  Superior  Proposal,  specifying  the
material  terms and  conditions of  such Superior  Proposal and  identifying the
person making such Superior Proposal. In addition, if Biocraft proposes to enter
into an agreement with  respect to any Takeover  Proposal, the Merger  Agreement
requires  Biocraft, concurrently with entering into such an agreement, to pay to
Teva the  fees  and  expenses  described  below under  '  --  Certain  Fees  and
Expenses'.  See  'THE  MERGER  --  Right  of  the  Biocraft  Board  to  Withdraw
Recommendation'.
 
     Certain Fees and Expenses.  The Merger Agreement  requires Biocraft to  pay
promptly  to  Teva a  termination  fee in  the amount  of  $6 million,  plus all
expenses described therein, if the Merger Agreement is terminated by Biocraft in
accordance with  the provisions  described above  under 'Right  of the  Biocraft
Board  to Withdraw Recommendation' or  is terminated by Teva  as a result of (i)
the withdrawal  or  modification  by  the Biocraft  Board  of  its  approval  or
recommendation  of  the Merger  to Biocraft's  stockholders  or its  approval or
recommendation to  Biocraft's  stockholders of  any  Takeover Proposal,  or  its
resolution to do the foregoing, (ii) the occurrence of a Third Party Acquisition
(as defined therein), or (iii) a material breach of any covenant, representation
or  warranty, of Biocraft in  the Merger Agreement or  the Special Meeting being
canceled or not being held by August 15, 1996 (except as a result of a judgment,
injunction, order or  decree of  any competent  authority or  events beyond  the
reasonable  control  of Biocraft)  and, within  12  months of  such termination,
Biocraft enters into an agreement with  certain persons with respect to a  Third
Party Acquisition, or a Third Party Acquisition occurs with certain persons. The
Merger  Agreement also requires  Teva to pay promptly  to Biocraft a termination
fee in the amount  of $6 million,  plus all expenses  described therein, if  the
Merger  Agreement  is  terminated  due  to  a  material  breach  of  a covenant,
representation or warranty of Teva in the Merger Agreement and, within 12 months
after such termination, Teva is acquired  by merger, tender offer or  otherwise,
or  a person acquires 20% or more of Teva's total assets or outstanding Ordinary
Shares or Teva enters into an agreement with respect to the foregoing.  Expenses
are  also  payable in  certain  other circumstances.  See  'TERMS OF  THE MERGER
AGREEMENT -- Certain Fees and Expenses'.
 
     Termination. The  Merger  Agreement  may  be  terminated,  and  the  Merger
contemplated  thereby may be abandoned, at any time prior to the Effective Time,
whether before or  after approval  by the  stockholders of  Biocraft of  matters
presented  in connection with the Merger, (i) by mutual written consent of Teva,
Merger Sub  and  Biocraft,  (ii)  by  Teva  if  the  required  approval  of  the
stockholders  of Biocraft is not obtained or  the Special Meeting is canceled or
is  otherwise  not   held  prior  to   August  15,  1996   (except  in   certain
circumstances),  or (iii) by either Teva or Biocraft if (a) the Merger shall not
have been consummated on or before August 31, 1996, (b) any law or regulation of
any competent authority  makes the  Merger illegal  or prohibited  or any  final
judgment,  injunction, order or decree prohibits the Merger or (c) if there is a
material breach of a covenant or a breach of a representation or warranty  which
breach  materially and adversely affects the  value of the breaching party which
is  not  cured  within  the  specified  period,  (iv)  by  Biocraft,  under  the
circumstances set forth above under 'Right of the
 
                                       10
 
<PAGE>
 
<PAGE>
Biocraft  Board to Withdraw Recommendation'  or (v) by Teva  if (a) the Biocraft
Board shall have withdrawn or modified in a manner adverse to Teva its  approval
or  recommendation  of  the  Merger  or the  Merger  Agreement,  or  approved or
recommended any Takeover  Proposal, or  resolved to  take any  of the  foregoing
actions, or (b) a Third Party Acquisition shall have occurred. See 'TERMS OF THE
MERGER AGREEMENT -- Termination Rights'.
 
IRREVOCABLE PROXY AND TERMINATION RIGHTS AGREEMENT
 
     As  an  inducement for  Teva  to enter  into  the Merger  Agreement, Harold
Snyder, Biocraft's  current Chairman,  Chief  Executive Officer  and  President,
Beatrice  Snyder, Biocraft's  current Senior  Vice President  and Secretary, and
their children as  trustees for certain  trusts which Mr.  and Mrs. Snyder  have
established,  holding  in the  aggregate  approximately 60%  of  the outstanding
Biocraft Common Stock,  have executed  the Irrevocable Proxy  pursuant to  which
such  stockholders have appointed Teva their lawful agent, attorney and proxy to
vote such shares of Biocraft Common Stock  in favor of the Merger Agreement  and
the  Merger.  In addition,  pursuant  to the  Irrevocable  Proxy, if  the Merger
Agreement is terminated in certain specified circumstances and a stockholder who
is a party to the Irrevocable Proxy  sells or otherwise disposes of any of  such
stockholder's  Biocraft Common Stock  pursuant to a  Third Party Acquisition (as
defined in the Merger Agreement), then  such stockholder is obligated to pay  to
Teva  such stockholder's Profit per Share (as defined therein) multiplied by the
number of shares  of Biocraft Common  Stock sold by  such stockholder. See  'THE
MERGER -- Irrevocable Proxy and Termination Rights Agreement'.
 
REGULATORY MATTERS
 
     Antitrust.   The   Merger   is   subject  to   the   requirements   of  the
Hart-Scott-Rodino Antitrust  Improvements  Act of  1976,  as amended  (the  'HSR
Act'),  and the  rules and  regulations thereunder,  which provide  that certain
transactions may not be consummated until required information and material have
been furnished  to the  Antitrust Division  of the  Department of  Justice  (the
'Antitrust  Division') and the Federal Trade  Commission (the 'FTC') and certain
waiting periods have  expired or been  terminated. Biocraft and  Teva filed  the
required  information and  material with the  Antitrust Division and  the FTC on
March 1, 1996. Early termination of  the statutory waiting period under the  HSR
Act  was granted on  March 28, 1996.  See 'THE MERGER  -- Regulatory Filings and
Approvals -- Antitrust'.
 
     Israeli Regulatory Approvals. The consummation of the Merger is conditioned
upon (i) there being in effect the consent of the Controller of Foreign Currency
of the Bank of Israel (the 'Controller of Foreign Currency') to the Merger,  the
issuance   of  the  Teva  Ordinary  Shares   and  certain  of  the  transactions
contemplated in  connection  with the  Merger,  (ii) Teva  having  received  the
required permit from the Israeli Securities Authority to publish a prospectus in
connection with the Merger or having obtained an exemption from such requirement
and  (iii)  consent in  principle  having been  granted  by the  Tel  Aviv Stock
Exchange ('TASE') to list  the Teva Ordinary Shares  to be issued in  connection
with  the Merger.  Teva has  obtained the consent  of the  Controller of Foreign
Currency to  the  Merger, the  issuance  of the  Teva  Ordinary Shares  and  the
transactions contemplated thereby. Teva has obtained from the Israeli Securities
Authority  an  exemption  from  the  requirement  to  publish  a  prospectus  in
connection with the Merger. Both the Listing and the Executive Committees of the
TASE have recommended to the TASE Board of Directors to consent in principle  to
list   the  Teva   Ordinary  Shares  to   be  issued  pursuant   to  this  Proxy
Statement/Prospectus. The TASE Board of  Directors is scheduled to consider  the
matter   on  May   2,  1996.   See  'THE   MERGER  --   Regulatory  Filings  and
Approvals -- Israeli Regulatory Approvals'.
 
CERTAIN TAX CONSEQUENCES OF THE MERGER
 
     The Merger is intended to qualify as a 'tax-free reorganization' for United
States Federal  income  tax purposes.  Accordingly,  no  gain or  loss  will  be
recognized  for  United  States  Federal income  tax  purposes  by  the Biocraft
stockholders as a result of the exchange of shares of Biocraft Common Stock  for
Teva  ADSs  representing  Teva  Ordinary Shares  in  the  Merger.  However, cash
received by Biocraft stockholders in lieu of fractional Teva ADSs may give  rise
to taxable gain or loss. In addition, any
 
                                       11
 
<PAGE>
 
<PAGE>
Biocraft  stockholder that is a United States  citizen or resident or a domestic
corporation and which owns (directly, indirectly or constructively) five percent
or more of the Teva Ordinary Shares immediately following the Effective Time may
have to comply with certain requirements  to avoid recognizing gain, if any,  on
the  exchange. Each stockholder of  Biocraft is urged to  consult his or her tax
advisor to  determine  the specific  tax  consequences  of the  Merger  to  such
stockholder.
 
     The  obligations of  Teva and  Biocraft to  consummate the  Merger are each
subject to the  receipt of an  opinion of  their respective tax  counsel to  the
effect  that the  Merger will be  a 'tax-free reorganization'  for United States
Federal income tax purposes. For a further discussion of the tax consequences of
the Merger, see 'THE MERGER -- Certain Tax Consequences of the Merger'.
 
ANTICIPATED ACCOUNTING TREATMENT
 
     Teva  and   Biocraft  believe   that   the  Merger   will  qualify   as   a
'pooling-of-interests'  for accounting and financial reporting purposes. It is a
condition to the  consummation of  the Merger  that Kesselman  & Kesselman,  the
independent  auditors for Teva, and Ernst  & Young LLP, the independent auditors
for Biocraft, issue their opinions that  there is no fact or circumstance  known
to  them concerning  Teva or Merger  Sub, on the  one hand, or  Biocraft, on the
other hand, respectively, which  would cause the Merger  not to be recorded  for
accounting   purposes   as  a   'pooling-of-interests'  transaction.   See  'THE
MERGER -- Anticipated Accounting Treatment'.
 
ABSENCE OF APPRAISAL RIGHTS
 
     Stockholders of Biocraft  will not  be entitled to  appraisal rights  under
Delaware  law  in connection  with the  Merger.  See 'THE  MERGER --  Absence of
Appraisal Rights'.
 
MARKET PRICE DATA
 
     Teva ADSs representing  Teva Ordinary Shares  (symbol: TEVIY) are  admitted
for  trading on  the NASDAQ National  Market and Biocraft  Common Stock (symbol:
BCL) is listed on the NYSE. Teva  Ordinary Shares are listed for trading on  the
Tel Aviv Stock Exchange.
 
     The  following table sets forth the high  and low sales prices per Teva ADS
on the NASDAQ National Market and per share of Biocraft Common Stock on the NYSE
(on a historical and equivalent per share  basis) on January 26, 1996, the  last
trading  day in the United States prior to public announcement of the signing of
the Merger Agreement:
 
<TABLE>
<CAPTION>
                                                                     HIGH      LOW
                                                                    ------    ------
 
<S>                                                                 <C>       <C>
Teva ADSs........................................................   $46.00    $45.25
Biocraft Common Stock
     Historical..................................................   $13.63    $12.75
     Equivalent share basis(1)...................................    21.21     20.86
</TABLE>
 
- ------------
 
(1) Equivalent share basis is determined by multiplying the applicable Teva  ADS
    price by 0.461 to reflect the terms of the Merger Agreement.
 
     The  last reported sales price of the  Teva Ordinary Shares on the Tel Aviv
Stock Exchange on January 28, 1995, the last trading day on such exchange  prior
to  public announcement of the signing of  the Merger Agreement, was $4.58. Each
Teva ADS represents 10 Teva Ordinary  Shares. See 'COMPARATIVE STOCK PRICES  AND
DIVIDENDS'.
 
CERTAIN SIGNIFICANT CONSIDERATIONS
 
     In  considering whether to approve and adopt the Merger Agreement providing
for the Merger, stockholders of Biocraft should carefully consider those factors
described under 'RISK FACTORS' as  well as the fact  that the Exchange Ratio  is
fixed  and will not be adjusted based on  changes in the price of the Teva ADSs,
and the price of the Teva ADSs at the Effective Time may vary from the price  as
of the date of this Proxy Statement/Prospectus or the date on which stockholders
of  Biocraft vote on  the Merger due  to changes in  the business, operations or
prospects of Teva, market assessments of the likelihood that the Merger will  be
consummated  and the timing thereof, general market and economic conditions, and
other factors.
 
                                       12
 
<PAGE>
 
<PAGE>
                               TEVA AND BIOCRAFT
           SELECTED HISTORICAL AND PRO FORMA COMBINED FINANCIAL DATA
 
     The following tables present selected historical financial data of Teva and
Biocraft and selected pro forma combined financial data, after giving effect  to
the  Merger under  the 'pooling  of interests'  method of  accounting as  if the
Merger had been consummated at the beginning of the periods presented, and, with
respect to the pro  forma statement of  income for the  year ended December  31,
1995,  after giving effect to the  acquisitions by Teva of Biogal Pharmaceutical
Works Ltd. and Industrie Chimiche Italiane S.p.A. under the 'purchase' method of
accounting, as if they had occurred as of January 1, 1995. Teva's and Biocraft's
historical financial data  for each of  the annual periods  presented have  been
derived   from  their  respective   audited  consolidated  financial  statements
previously filed with the SEC. Biocraft's historical financial data for the nine
months ended  December 31,  1995  and 1994  presented,  have been  derived  from
Biocraft's  unaudited financial  statements previously  filed with  the SEC. All
such financial statements have been incorporated by reference herein. Biocraft's
unaudited interim financial  information as  of December  31, 1995  and for  the
periods ended December 31, 1995 and 1994 includes all adjustments (consisting of
only  normal  recurring accruals)  which are,  in the  opinion of  management of
Biocraft, necessary for  a fair presentation  of the results  of operations  for
such  interim periods. Operating results for  the nine months ended December 31,
1995 are not necessarily indicative of the results that may be achieved for  the
year  ended March 31, 1996. Biocraft's  historical financial data should be read
in conjunction with 'Management's Discussion and Analysis of Financial Condition
and Results of Operations' and the consolidated financial statements and related
notes thereto incorporated  by reference herein.  The historical financial  data
for  Teva are presented for each of the  five years in the period ended December
31, 1995. Biocraft's  historical financial data  are presented on  the basis  of
fiscal years ended March 31.
 
     The  selected pro forma combined financial  data have been derived from, or
prepared on a basis consistent with, the unaudited pro forma combined  financial
statements  included in this Proxy  Statement/Prospectus. Pro forma earnings per
Teva ADS are computed assuming that 0.461  Teva ADSs are issued in exchange  for
each share of Biocraft Common Stock in the Merger. For purposes of the pro forma
information,  Biocraft's  financial data  for  all periods  presented  have been
recast to reflect the results of operations  on a calendar year basis, prior  to
combination  of those results with  the results of Teva.  The selected pro forma
combined financial data should be read in conjunction with, and is qualified  in
its  entirety by reference  to, the unaudited pro  forma combined financial data
and the notes  thereto. See  'UNAUDITED PRO FORMA  COMBINED CONDENSED  FINANCIAL
STATEMENTS'. The following data are presented for illustrative purposes only and
are  not necessarily indicative  of the operating  results or financial position
that would have occurred or that will occur after consummation of the Merger.
 
                                       13
 
<PAGE>
 
<PAGE>
                                TEVA HISTORICAL
 
<TABLE>
<CAPTION>
                                                                           YEARS ENDED DECEMBER 31,
                                                              ---------------------------------------------------
                                                               1995       1994       1993       1992       1991
                                                              -------    -------    -------    -------    -------
                                                                (IN THOUSANDS US DOLLARS, EXCEPT PER ADS DATA)
<S>                                                           <C>        <C>        <C>        <C>        <C>
Operating Data:
     Sales.................................................   667,677    587,711    501,975    396,336    320,983
     Gross profit..........................................   278,158    258,478    213,855    154,387    117,034
     Write-off in accordance with General Health Fund debt
       arrangement.........................................     4,745      --         --         --         --
     Operating income......................................   110,413    106,730     87,981     54,729     35,477
     Net income............................................    79,792     71,646     57,475     31,734     23,282
     Earnings per ADS
          Primary..........................................      1.46       1.32       1.07       0.61       0.49
          Fully diluted....................................      1.46       1.32       1.07       0.61       0.46
     Weighted average number of ADSs outstanding:
          Primary..........................................    55,112     54,968     54,950     54,111     47,120
          Fully diluted....................................    55,112     54,968     54,950     54,111     51,109
     Cash dividends per ADS................................      0.26       0.26       0.21       0.11       0.09
Balance Sheet Data at End of Period:
     Working capital.......................................    64,792    159,782    123,577     90,775    102,315
     Total assets..........................................   871,294    675,983    562,917    433,650    368,623
     Long-term debt........................................    40,763     80,838     50,914     12,769     23,348
     Shareholders' equity..................................   402,883    342,037    267,526    216,538    178,977
     Book value per ADS....................................      7.38       6.26       5.05       4.18       3.80
U.S. GAAP Data
Net income.................................................    81,461     70,095     53,848     36,414     23,282
     Earnings per ADS:
          Primary..........................................      1.49       1.29       1.00       0.69       0.49
          Fully diluted....................................      1.49       1.29       1.00       0.69       0.46
</TABLE>
 
                              BIOCRAFT HISTORICAL
 
<TABLE>
<CAPTION>
                                                NINE MONTHS
                                                   ENDED
                                               DECEMBER 31,                    FISCAL YEARS ENDED MARCH 31,
                                        ---------------------------   -----------------------------------------------
                                            1995           1994        1995      1994      1993      1992      1991
                                        ------------   ------------   -------   -------   -------   -------   -------
                                                      (IN THOUSANDS US DOLLARS, EXCEPT PER SHARE DATA)
 
<S>                                     <C>            <C>            <C>       <C>       <C>       <C>       <C>
Operating Data:
     Sales............................     106,729        102,891     140,794   143,149   113,176    84,259    76,121
     Gross profit.....................      14,360         17,534      25,085    33,509    24,005     9,434    17,952
     Net income (loss)................      (4,726)        (2,533)     (2,395)    6,105     5,856    (6,740)    3,708
     Earnings (loss) per share........       (0.33)         (0.18)      (0.17)     0.43      0.42     (0.48)     0.27
     Cash dividends per share.........          --           0.10        0.10      0.10      0.10      0.10      0.10
Balance Sheet Data at End of Period:
     Working capital..................      55,145         55,452      60,177    63,256    60,642    60,032    62,919
     Total assets.....................     183,275        170,879     172,945   168,073   170,147   164,252   157,378
     Long-term debt...................      52,402         46,596      50,800    48,582    52,255    56,405    45,109
     Shareholders' equity.............      89,751         93,701      93,981    97,292    91,867    86,320    93,286
     Book value per share.............        6.33           6.61        6.63      6.88      6.52      6.15      6.68
</TABLE>
 
                                       14
 
<PAGE>
 
<PAGE>
                   SUMMARY PRO FORMA COMBINED FINANCIAL DATA
                               TEVA AND BIOCRAFT
 
<TABLE>
<CAPTION>
                                                                                       1995        1994       1993
                                                                                     ---------    -------    -------
                                                                                        (IN THOUSANDS US DOLLARS,
                                                                                          EXCEPT PER ADS DATA)
<S>                                                                                  <C>          <C>        <C>
Operating Data:
    Sales.........................................................................     894,454    724,857    648,727
    Gross profit..................................................................     316,080    281,848    252,511
    Write-off in accordance with General Health Fund debt arrangement.............       4,745         --         --
    Operating income..............................................................     107,622    103,955    104,487
    Net income....................................................................      74,818     68,454     66,596
    Earnings per ADS..............................................................        1.22       1.12       1.10
    Weighted Average Number of ADSs Outstanding...................................      61,678     61,534     61,516
    Cash dividends per ADS*.......................................................        0.26       0.26       0.21
Balance Sheet Data at End of Year:
    Working capital...............................................................      97,387         --         --
    Total assets..................................................................   1,040,637         --         --
    Long-term debt................................................................      93,165         --         --
    Shareholders' equity..........................................................     473,767         --         --
    Book value per ADS............................................................        7.75
U.S. GAAP Data:
    Net income....................................................................      75,286     69,176     67,745
    Earnings per ADS..............................................................        1.22       1.12       1.10
</TABLE>
 
- ------------
 
* Pro forma combined cash dividends per ADS reflect Teva cash dividends declared
  for the years presented.
 
                     COMPARATIVE PER ADS AND PER SHARE DATA
 
     The following table  sets forth certain  historical per ADS  and per  share
data  of Teva and Biocraft  and combined per ADS data  on an unaudited pro forma
basis after  giving effect  to the  Merger  on a  'pooling of  interests'  basis
assuming  that 0.461 Teva ADSs are issued in exchange for each share of Biocraft
Common Stock in the  Merger. This data  should be read  in conjunction with  the
selected  historical financial data, the pro forma combined financial statements
and the separate historical  financial statements of Teva  and Biocraft and  the
notes  thereto,  included  in, or  incorporated  by reference  into,  this Proxy
Statement/Prospectus. The unaudited  pro forma combined  financial data are  not
necessarily  indicative of the  operating results that  would have been achieved
had the Merger been in effect as  of the beginning of the periods presented  and
should not necessarily be construed as representative of future operations.
<TABLE>
<CAPTION>
                                                                              YEAR ENDED MARCH 31,
                                                                             -----------------------
                                                                             1995      1994     1993
                                                                             -----     ----     ----
                                                                                  (US DOLLARS)
<S>                                                                          <C>       <C>      <C>
Biocraft -- historical
    Earnings (loss) per share.............................................   (0.17)    0.43     0.42
    Cash dividends per share..............................................    0.10     0.10     0.10
    Book value per share..................................................    6.63     6.88     6.52
 
<CAPTION>
                                                                             YEAR ENDED DECEMBER 31,
                                                                             -----------------------
                                                                             1995      1994     1993
                                                                             -----     ----     ----
                                                                                  (US DOLLARS)
<S>                                                                          <C>       <C>      <C>
Teva -- historical
    Earnings per ADS......................................................    1.46     1.32     1.07
    Cash dividends per ADS................................................    0.26     0.26     0.21
    Book value per ADS....................................................    7.38     6.26     5.05
Pro forma combined
    Earnings per ADS......................................................    1.22     1.12     1.10
    Cash dividends per ADS*...............................................    0.26     0.26     0.21
    Book value per ADS....................................................    7.75     --       --
Biocraft pro forma equivalents
    Earnings per share....................................................    0.56     0.52     0.51
    Cash dividends per share..............................................    0.12     0.12     0.10
    Book value per share..................................................    3.57     --       --
</TABLE>
 
- ------------
 
* Pro forma combined cash dividends per ADS reflect Teva cash dividends declared
  for the years presented.
 
                                       15



<PAGE>
 
<PAGE>
                                  RISK FACTORS
 
     In  addition to the  other information in  this Proxy Statement/Prospectus,
the following  factors should  be considered  carefully by  the stockholders  of
Biocraft  in  evaluating  whether  to approve  and  adopt  the  Merger Agreement
providing for the Merger. The Private  Securities Litigation Reform Act of  1995
provides  a 'safe  harbor' for forward  looking statements.  Any forward looking
statements contained  in  this Proxy  Statement/Prospectus,  including,  without
limitation, those relating to the combined operations of Teva and Biocraft after
the Merger, are subject to, among other things, such factors.
 
FIXED EXCHANGE RATIO
 
     In  considering whether to approve and adopt the Merger Agreement providing
for the  Merger, stockholders  of Biocraft  should carefully  consider that  the
Exchange  Ratio is fixed and will not be  adjusted based on changes in the price
of the Teva ADSs, and the price of the Teva ADSs at the Effective Time may  vary
from  the price as of the date of this Proxy Statement/Prospectus or the date on
which stockholders  of  Biocraft  vote on  the  Merger  due to  changes  in  the
business,  operations or prospects of Teva, market assessments of the likelihood
that the Merger will be consummated  and the timing thereof, general market  and
economic conditions, and other factors.
 
DIFFICULTY OF INTEGRATION OF OPERATIONS FOLLOWING THE MERGER
 
     The Teva Board and the Biocraft Board have each given careful consideration
to  the Merger and  believe it to be  in the best  interests of their respective
stockholders. However, the Merger involves the combination of two companies that
have operated  independently.  Accordingly,  there  can  be  no  assurance  that
Biocraft  can  be  successfully  integrated  into  Teva  or  that  Teva  and its
shareholders (including the stockholders of Biocraft who become shareholders  of
Teva)  will ultimately realize any benefits from  the Merger. The success of the
combined company following the Merger will require the dedication of  management
resources  which  may  temporarily detract  from  attention  to the  day  to day
business of Teva and Biocraft. There can be no assurance that there will not  be
high costs associated with integrating the two companies, that such diversion of
management  resources will not adversely affect  revenues or that other material
adverse effects will not result from such activities.
 
REGULATORY STATUS OF COPAXONE'r'
 
     During 1995, Teva filed applications for marketing approval of  Copaxone'r'
(co-polymer-1),  Teva's  innovative  product  for  the  treatment  of relapsing,
remitting multiple  sclerosis,  with  the  U.S.  Food  and  Drug  Administration
('FDA'),  the  United Kingdom's  Medicines Control  Agency  (the 'MCA')  and the
Israeli Ministry  of Health.  In addition,  Teva has  built facilities  for  the
production  of  Copaxone'r'  which  must also  be  approved  by  such regulatory
authorities. However,  there can  be no  assurance that  the FDA,  the MCA,  the
Israeli Ministry of Health or any other governmental agency will grant marketing
approval  for  this  product  or  approval for  these  facilities  or  when such
approvals will  be  forthcoming. Failure  to  obtain, or  delays  in  obtaining,
regulatory  approval of this  product or difficulties in  the production of this
product on a  commercial scale  could adversely affect  Teva. Teva  is aware  of
other  products for the treatment of multiple sclerosis, one of which is already
on the market. As competitors enter  this market, the resulting competition  may
adversely affect the market for, and the price of, Copaxone'r'.
 
BIOCRAFT'S HISTORY OF REGULATORY PROBLEMS
 
     In  July  1994, Biocraft  entered into  a  consent decree  with the  FDA to
resolve  outstanding  regulatory  issues  with   respect  to  its  dosage   form
facilities.  Among other things, the consent decree required Biocraft to suspend
shipments of  certain products  until Biocraft  satisfied certain  requirements.
Biocraft  also had  to obtain  and submit  to the  FDA expert  certifications of
procedures used  in  the manufacturing  and  testing  of the  remainder  of  its
products,  scheduled periodically over an 18-month period. In November 1995, the
FDA completed its inspection of Biocraft's research and development laboratories
in connection with  new product submissions  and issued its  findings on a  Form
483.  At the end of  January 1996, Biocraft submitted  the final group of expert
certifications in accordance with the consent decree. Although Biocraft believes
that   it   has    responded   adequately    to   the   Form    483   and    has
 
                                       16
 
<PAGE>
 
<PAGE>
satisfactorily  completed all expert certifications,  no assurances can be given
that the  FDA  will find  such  responses or  certifications  acceptable.  Since
February  1996 Biocraft has received approvals  from the FDA to manufacture four
new generic drugs  including sucralfate,  an antiulcer drug  for which  Biocraft
received  the  first  generic  approval.  These  approvals  are  the  first such
approvals which Biocraft has received in  over two and one half years.  Biocraft
cannot predict the timing of its receipt of any additional new drug approvals as
a result of the FDA's continuing review of the Form 483 response, certifications
or  other matters  which they may  choose to consider  or subsequent inspections
that they  may require.  Were Biocraft's  regulatory problems  with the  FDA  to
continue or new ones to arise, or were Teva to experience significant regulatory
problems  with  the FDA,  the results  of operations  of the  combined companies
following the Merger would be materially and adversely affected.
 
DEPENDENCY ON PRODUCT DEVELOPMENT
 
     The future results  of operations of  Teva and Biocraft  will depend, to  a
certain  degree,  upon their  ability  to successfully  commercialize additional
generic and/or innovative branded  pharmaceutical products. Innovative  products
must  be developed, tested  and manufactured, as  well as proven  to be safe and
effective in  clinical  trials.  Generic  products must  be  proven  to  be  the
bioequivalent  of the branded counterpart, and all products must meet regulatory
standards and  receive  requisite  regulatory  approvals.  The  development  and
commercialization  process is  both time consuming  and costly. There  can be no
assurance that  any products  presently  under development,  if and  when  fully
developed  and  tested, will  perform in  accordance  with Teva's  or Biocraft's
expectations, that necessary regulatory approvals  will be obtained in a  timely
manner,  if  at  all, or  that  any of  such  products can  be  successfully and
profitably produced  and marketed.  Delays in  any part  of the  process or  the
inability  of Teva or  Biocraft to obtain regulatory  approval of their products
could adversely affect the respective operating results of Teva and Biocraft and
the combined company following the Merger.
 
COMPETITION AND TECHNOLOGICAL CHANGE
 
     In the United States, Teva and Biocraft experience substantial  competition
in  connection with  the manufacture and  sale of  generic pharmaceuticals. Many
competitors,   including   divisions   and   subsidiaries   of   large   branded
pharmaceutical  companies that market off-patent  drugs, have greater financial,
technical, clinical, marketing and other  resources than Teva and Biocraft  and,
therefore,  are able  to expend  more than  Teva and  Biocraft in  areas such as
research, marketing and  product development.  Although a  company with  greater
resources  will not necessarily receive FDA approval for a particular off-patent
drug before its smaller competitors,  relatively large research and  development
expenditures  enable a company to  support many FDA applications simultaneously,
thereby improving  the likelihood  that it  will be  among the  first to  obtain
approval  of at  least some  off-patent drugs.  Selling prices  of generic drugs
typically decline,  sometimes  dramatically,  as  additional  companies  receive
Abbreviated  New Drug Applications  ('ANDAs') approvals for  a given product and
competition intensifies, including price  competition from the branded  product.
Teva's  and Biocraft's profitability will thus depend, in part, on their ability
to maintain efficient production and to develop and introduce new products in  a
timely manner.
 
     In addition, competition in the United States generic pharmaceutical market
continues  to  intensify as  the  pharmaceutical industry  adjusts  to increased
pressures to contain health  care costs. Brand  name companies are  increasingly
selling  their products into the generic market directly by acquiring or forming
strategic  alliances  with  generic  pharmaceutical  companies.  No   regulatory
approvals are required for a brand name manufacturer to sell directly or through
a  third party to the  generic market, nor do  such manufacturers face any other
significant barriers  to entry  into such  market. In  addition, such  companies
continually  seek  to  find new  ways  to  defeat generic  competition,  such as
developing patented controlled release products  or developing and marketing  as
over-the-counter products those branded products which are about to face generic
competition. The competitive environment will continue to affect both Teva's and
Biocraft's  respective pharmaceutical operations. The  markets in which Teva and
Biocraft operate are undergoing, and are expected to continue to undergo,  rapid
and  significant technological change, and  Teva and Biocraft expect competition
to intensify as technological
 
                                       17
 
<PAGE>
 
<PAGE>
advances in such fields are made. There can be no assurance that developments by
others will not render the products or technologies of Teva or Biocraft obsolete
or uncompetitive.
 
GOVERNMENT REGULATION
 
     Teva is subject to extensive pharmaceutical industry regulation in  Israel,
the  United States, Hungary and other  jurisdictions, and Biocraft is subject to
such regulation in the United States. Neither Teva nor Biocraft can predict  the
extent  to  which  it  may  be  affected  by  legislative  and  other regulatory
developments concerning its products.
 
     In Israel, the manufacture and sale of pharmaceutical products is regulated
in  a  manner  substantially  similar  to  that  in  the  United  States.  Legal
requirements   generally  prohibit  the  handling,  manufacture,  marketing  and
importation of any pharmaceutical unless it is properly registered in accordance
with applicable law. The  registration file relating  to any particular  product
must  contain medical  data related  to product  efficacy and  safety, including
results of clinical testing  and references to medical  publications as well  as
detailed  information  regarding  production methods  and  quality  control. The
Ministry of Health is authorized to cancel the registration of a  pharmaceutical
if found to be harmful or ineffective or manufactured and marketed other than in
accordance with the registration conditions.
 
     In  the United States,  Teva's innovative products  are subject to rigorous
preclinical and  clinical testing  for  safety and  efficacy  as well  as  other
approval  processes of  New Drug  Applications ('NDAs')  by the  FDA and similar
health authorities in other countries.  The process of obtaining such  approvals
is  time consuming  and costly.  There can be  no assurance  that any innovative
products developed by  Teva will  be determined to  be safe  and efficacious  in
clinical  trials or  meet other applicable  regulatory standards  to receive the
necessary approvals for manufacture and marketing.
 
     Teva and  Biocraft,  as  well  as other  generic  drug  manufacturers,  are
dependent  on obtaining timely approvals of  ANDAs from the FDA before marketing
most of its products. Any manufacturer  failing to comply with FDA  requirements
may be unable to obtain approvals for the introduction of new products and, even
after  approval, initial product shipments may be  delayed. The FDA also has the
authority to revoke drug approvals previously granted and remove from the market
previously approved drug products containing  ingredients no longer approved  by
the  FDA. Teva's and  Biocraft's major facilities  and products are periodically
inspected by the FDA, which has extensive enforcement powers over the activities
of pharmaceutical manufacturers, including the  power to seize, force to  recall
and prohibit the sale or import of noncomplying products, and halt operations of
and  criminally  prosecute noncomplying  manufacturers. Any  failure by  Teva or
Biocraft to comply  with applicable FDA  policies and regulations  could have  a
material adverse effect on the operations of Teva or Biocraft.
 
PRODUCT LIABILITY
 
     The  businesses of  Teva and Biocraft  inherently expose  them to potential
liability. From  time  to  time, the  pharmaceutical  industry  has  experienced
difficulty in obtaining desired amounts of product liability insurance coverage.
Biocraft effectively self-insures its product liability coverage. If any product
liability  claim not  covered by insurance  or exceeding the  policy limits were
sustained against  Teva,  or  if  any  material  product  liability  claim  were
sustained  against  Biocraft, it  could have  a material  adverse effect  on the
respective businesses and financial conditions of such companies.
 
PHARMACEUTICAL PRICING AND HEALTH CARE REFORM
 
     Increasing  expenditures  for  health  care   have  been  the  subject   of
considerable  public attention in Israel, the United States and Western European
countries. Both private and  governmental entities are seeking  to find ways  to
reduce  or contain health care costs. In  many countries in which Teva currently
operates, including Israel, pharmaceutical prices are subject to regulation.  In
the  United  States,  numerous proposals  have  been introduced  or  proposed in
Congress and in some state legislatures that would effect changes in the  United
States  health care system. Similar activities  are taking place in Europe. Teva
and Biocraft cannot predict the  nature of the measures  that may be adopted  or
their
 
                                       18
 
<PAGE>
 
<PAGE>
impact  on the  respective results  of operations of  Teva and  Biocraft and the
combined company following the Merger.
 
LEGAL PROCEEDINGS
 
     On March 31, 1996, an  indictment relating to tax  issues was filed by  the
Jerusalem district attorney's office against Promedico Ltd., a former subsidiary
of  Teva ('Promedico'), as  well as certain  of its officers,  including Mr. Eli
Hurvitz, the President and C.E.O. of Teva, who served during the period in which
Promedico was owned by  Teva (1980   - 1986) as the  chairman of Promedico.  The
charges  allege: failure to report  commissions allegedly received by Promedico;
failure to register such commissions in Promedico's books; failure to pay  taxes
which  may  be due  on such  commissions; and  fraudulent actions  regarding the
foregoing. The charges are attributed to Mr. Hurvitz by reason of his serving as
the  chairman  of  the  board  of  directors  of  Promedico  between  the  years
1980   - 1986. Mr. Hurvitz denies any  culpability in regard to this matter, and
the Board of Directors of Teva has expressed its fullest confidence and  support
of  his ability to continue managing Teva and that Mr. Hurvitz will be fully and
completely exonerated. While Teva is not a party to these proceedings, there can
be no assurance as to  the outcome of these proceedings  or any effect they  may
have on the operations of Teva.
 
FOREIGN OPERATIONS
 
     A  significant portion of  the operations of Teva  are conducted outside of
the United  States.  Teva may,  therefore,  be directly  affected  by  economic,
political  and military conditions in  the countries in which  it is located, as
well as  by  currency  exchange  rate  fluctuations  and  the  exchange  control
regulations  of such countries. Teva's executive offices and the majority of its
manufacturing facilities  are located  in the  State of  Israel. Teva's  Israeli
operations  are dependent upon  materials imported from  outside of Israel. Teva
also exports  significant  amounts of  products  from Israel.  Accordingly,  the
operations  of Teva could be materially  adversely affected by acts of terrorism
or if major  hostilities involving  Israel should occur  in the  Middle East  or
trade between Israel and its present trading partners should be curtailed.
 
RISK OF MORE LIMITED INFORMATION FROM FOREIGN PRIVATE ISSUER
 
     Teva  is subject to the informational requirements of the Exchange Act that
are applicable to foreign private  issuers, which differ significantly from  the
reporting  requirements applicable to  U.S. issuers such  as Biocraft. After the
Merger, the former stockholders of Biocraft will only be entitled to receive  as
shareholders  of Teva  those reports  required of  foreign private  issuers. For
example, Teva  is  currently  exempt  from the  rules  under  the  Exchange  Act
prescribing  the furnishing and  content of proxy  statements, and its officers,
directors  and  principal  shareholders  are  exempt  from  the  reporting   and
short-swing profit recovery provisions contained in Section 16 of such Act. Teva
is  not  required under  the  Exchange Act  to  publish financial  statements as
frequently or as promptly as are United States companies subject thereto.
 
SERVICE AND ENFORCEMENT OF LEGAL PROCESS
 
     Service of process upon Teva, its  directors and the experts named  herein,
most of whom reside outside the United States, may be difficult to obtain within
the  United States.  Furthermore, since  most of  Teva's assets  are outside the
United States, any judgment obtained in  the United States against Teva may  not
be  collectible within the United States. Teva has appointed Lemmon Company, 650
Cathill Road, Sellersville,  Pennsylvania, as  its agent to  receive service  of
process in any action against Teva in any federal court or court in the State of
New  York  arising out  of the  issuance  of securities  pursuant to  this Proxy
Statement/Prospectus. In addition, Teva has submitted to the jurisdiction of any
state or federal court sitting in the State of New York with respect to any suit
arising out  of,  under or  in  connection with  the  Merger Agreement  and  has
appointed  CT Corporation System in the City of New York as its agent to receive
process in any such suit.
 
     Teva has been informed by its legal  counsel in Israel, S. Horowitz &  Co.,
that  there is  doubt as  to the enforceability  of civil  liabilities under the
Securities Act or the Exchange Act in original actions
 
                                       19
 
<PAGE>
 
<PAGE>
instituted in Israel. However, subject  to certain time limitations, an  Israeli
court  may declare a foreign civil judgment enforceable if it finds that (1) the
judgment was given in a state the  courts of which were, according to its  laws,
competent  to  give  it, (2)  the  judgment  is no  longer  appealable,  (3) the
obligation imposed  by  the  judgment  is enforceable  according  to  the  rules
relating  to the enforceability  of judgments in  Israel and its  content is not
contrary to public  policy and (4)  the judgment  is executory in  the state  in
which  it was given. A  foreign judgment will not  be declared enforceable if it
was given in a  state the laws of  which do not provide  for the enforcement  of
judgments of Israeli courts (subject to exceptional cases) or if its enforcement
is likely to prejudice the sovereignty or security of Israel. A foreign judgment
will  also not be enforceable if it is  proven to the Israeli court that (a) the
judgment was obtained by fraud, (b) there  was no due process, (c) the  judgment
was  given by a court not competent to give it according to the rules of private
international law  in Israel,  (d)  the judgment  is  at variance  with  another
judgment  given in the same  matter between the same  parties and still valid or
(e) at the time the action was brought  in the foreign court a suit in the  same
matter  and between the same  parties was pending before  a court or tribunal in
Israel.
 
     Under existing law, a foreign judgment  payable in foreign currency may  be
paid in Israeli currency at the rate of exchange on the date of payment, but the
judgment  debtor  may  also make  payment  in  foreign currency  if  the Israeli
exchange control  regulations  then  in  effect  permit  such  foreign  currency
payment.  Pending collection,  the amount  of the  judgment of  an Israeli court
stated in Israeli  currency will ordinarily  be linked to  the Israeli  consumer
price  index. For  judgments recovered  in Israeli  currency, judgment creditors
must bear the risk that they will be unable to convert their award into  foreign
currency  that can  be transferred out  of Israel. Such  judgment creditors must
also bear the risk of unfavorable exchange rates.
 
                              THE SPECIAL MEETING
 
SPECIAL MEETING
 
     This Proxy Statement/Prospectus is being furnished to Biocraft stockholders
in connection with the solicitation by the Biocraft Board of proxies for use  at
the  Special Meeting to  be held on Friday,  May 31, 1996,  at 10:00 a.m., local
time, at the Marriott at Glenpointe, 100 Frank Burr Blvd., Teaneck, New Jersey.
 
     At the Special Meeting, holders of Biocraft Common Stock will consider  and
vote  upon  a proposal  to approve  the Merger  Agreement. The  Merger Agreement
provides that, upon the terms and subject to the conditions thereof, Merger  Sub
will  be merged with and  into Biocraft and Biocraft  will become a wholly owned
subsidiary of Teva. Each share of  Biocraft Common Stock issued and  outstanding
immediately prior to the Merger will be converted into the right to receive that
number  of validly issued, fully  paid and nonassessable Teva  ADSs equal to the
Exchange Ratio.
 
     No fractional Teva ADSs will be issued  in the Merger. In lieu of any  such
fractional  Teva ADSs, each holder of  Biocraft Common Stock who otherwise would
be entitled to receive  a fractional Teva ADS  pursuant to the Merger  Agreement
will  be  paid an  amount  in cash,  without  interest, equal  to  such holder's
proportionate interest in the net proceeds  from the sale by the Exchange  Agent
(as  defined  below) on  behalf  of all  such holders  of  the aggregate  of the
fractions of Teva ADSs which would otherwise be issued.
 
     THE BIOCRAFT BOARD HAS UNANIMOUSLY ADOPTED THE MERGER AGREEMENT, DETERMINED
THAT THE MERGER IS IN THE BEST  INTERESTS OF BIOCRAFT AND ITS STOCKHOLDERS,  AND
RECOMMENDS THAT THE STOCKHOLDERS OF BIOCRAFT VOTE FOR THE APPROVAL OF THE MERGER
AGREEMENT.  SEE 'THE MERGER -- BACKGROUND OF THE MERGER' AND ' -- RECOMMENDATION
OF THE BIOCRAFT BOARD AND BIOCRAFT'S REASONS FOR THE MERGER'.
 
     The Teva  Board of  Directors has  approved the  Merger Agreement  and  the
issuance  of Teva ADSs representing Teva Ordinary  Shares in the Merger, and the
Board of Directors of Merger  Sub, and Teva, as  the sole stockholder of  Merger
Sub,  have respectively adopted  and approved the  Merger Agreement. Approval of
the Merger Agreement and  the Merger by Teva's  shareholders is not required  to
effect the Merger.
 
                                       20
 
<PAGE>
 
<PAGE>
RECORD DATE; SHARES ENTITLED TO VOTE
 
     The  close of business on April 22, 1996  has been fixed as the Record Date
for determining the holders of Biocraft Common Stock who are entitled to  notice
of  and  to vote  at the  Special Meeting.  As  of the  Record Date,  there were
14,184,843 shares of Biocraft Common Stock outstanding and entitled to vote, and
such shares were held by approximately  761  holders of record.  The  holders of
record on the Record Date of Biocraft Common Stock are entitled to one vote  per
share of Biocraft Common Stock on each matter submitted to a vote at the Special
Meeting.  The presence in person or by proxy of the holders of a majority of the
outstanding Biocraft Common Stock entitled to vote is necessary to constitute  a
quorum  for the transaction of  business at the Special  Meeting. As a result of
the Irrevocable Proxy, such quorum requirement  for the Special Meeting will  be
met.
 
     Proxies  relating to  'street name' shares  that are  properly executed and
returned  by  brokers  will  be  counted  as  shares  present  for  purposes  of
determining  the presence of a quorum, but  will not be treated as shares having
voted at the Special Meeting as to the Merger Agreement if authority to vote has
been withheld by the broker (a 'broker non-vote'). Abstentions will be  recorded
as  such by the inspectors of election for  the Special Meeting. In light of the
treatment of broker non-votes and abstentions and the fact that the  affirmative
vote  required to approve the Merger Agreement is two-thirds of the total number
of outstanding  shares of  Biocraft  Common Stock  on  the Record  Date,  broker
non-votes and abstentions will have the same effect as votes against approval of
the Merger Agreement.
 
VOTE REQUIRED AND IRREVOCABLE PROXY
 
     The  affirmative vote of holders of two-thirds (66-2/3%) of the outstanding
shares of  the Biocraft  Common Stock  is required  for approval  of the  Merger
Agreement.  As of April 22, 1996,  the Biocraft directors and executive officers
and their affiliates as a group held shares representing approximately 64.2%  of
the  outstanding  shares of  Biocraft Common  Stock. Each  of the  directors and
executive officers of  Biocraft who  owns shares  of Biocraft  Common Stock  has
advised  Biocraft that  he/she intends to  vote or  direct the vote  of all such
shares over which he/she has voting control, subject to and consistent with  any
fiduciary  obligations in the case  of shares held as  a fiduciary, for approval
and adoption  of  the  Merger Agreement  and  the  Merger. In  addition,  as  an
inducement  for Teva to enter into the  Merger Agreement, each of Harold Snyder,
Biocraft's current  Chairman, Chief  Executive Officer  and President,  Beatrice
Snyder,  Biocraft's  current  Senior  Vice President  and  Secretary,  and their
children as  trustees  for  certain  trusts  which  Mr.  and  Mrs.  Snyder  have
established,  holding  in the  aggregate  approximately 60%  of  the outstanding
shares of Biocraft  Common Stock,  has executed the  Irrevocable Proxy  whereby,
among  other things, such  stockholder has irrevocably  appointed Teva as agent,
attorney and proxy to vote such stockholder's shares (i) in favor of the Merger,
(ii) in favor of the Merger  Agreement, (iii) against any Takeover Proposal  (as
defined in the Merger Agreement) (other than the Merger) or other proposal which
provides  for any merger,  sale of assets or  other business combination between
Biocraft and any other person or entity  or which would make it impractical  for
Teva to effect a merger or other business combination of Biocraft with Teva or a
wholly  owned subsidiary of Teva and (iv)  against any other action or agreement
that would result in a breach of any covenant, representation or warranty or any
other obligation or agreement  of Biocraft under the  Merger Agreement or  which
could  result in  any of Biocraft's  obligations under the  Merger Agreement not
being fulfilled. As  of the  Record Date, Teva  owned no  outstanding shares  of
Biocraft  Common Stock.  See 'THE  MERGER --  Irrevocable Proxy  and Termination
Rights Agreement'.
 
PROXIES; PROXY SOLICITATION
 
     Shares of Biocraft Common Stock represented by properly executed, unrevoked
proxies received at or prior to the Special Meeting will be voted at the Special
Meeting in  accordance  with  the  instructions  contained  therein.  Shares  of
Biocraft  Common Stock represented  by properly executed,  unrevoked proxies for
which no  instruction  is  given  will  be voted  FOR  approval  of  the  Merger
Agreement.  Biocraft  stockholders are  requested  to complete,  sign,  date and
return promptly the enclosed  proxy card in  the postage-paid envelope  provided
for  this purpose to ensure that their  shares are voted. A Biocraft stockholder
may revoke a proxy by  submitting a later dated proxy  with respect to the  same
shares at any time prior to the vote on the approval of the Merger Agreement, by
delivering
 
                                       21
 
<PAGE>
 
<PAGE>
written  notice of revocation to the Secretary  of Biocraft at any time prior to
such vote  or  by attending  the  Special Meeting  and  voting in  person.  Mere
attendance at the Special Meeting will not in and of itself revoke a proxy.
 
     If  the Special Meeting is postponed or  adjourned for any reason, when the
Special Meeting is convened or reconvened, all proxies will be voted in the same
manner as such proxies would  have been voted at  the original convening of  the
meeting  (except for any proxies which  have heretofore effectively been revoked
or withdrawn), notwithstanding that they may have been effectively voted on  the
same or any other matter at a previous meeting.
 
     The  cost of the  solicitation of proxies by  Biocraft's Board of Directors
for use  at the  Special  Meeting will  be borne  by  Biocraft. In  addition  to
solicitation  by mail, directors, officers and employees of Biocraft may solicit
proxies by  telephone,  telegram  or otherwise.  Such  directors,  officers  and
employees of Biocraft will not be additionally compensated for such solicitation
but  may  be  reimbursed  by Biocraft  for  out-of-pocket  expenses  incurred in
connection therewith.  Brokerage firms,  fiduciaries  and other  custodians  who
forward  soliciting  material to  the beneficial  owners  of shares  of Biocraft
Common Stock held  of record  by them will  be reimbursed  for their  reasonable
expenses incurred in forwarding such material.
 
MISCELLANEOUS
 
     Representatives  of Ernst & Young LLP, Biocraft's independent auditors, are
expected to be  present at  the Special  Meeting. Such  representatives will  be
afforded  an opportunity to make  a statement, if they desire  to do so, and are
expected to be available to respond to appropriate questions.
 
                                   THE MERGER
 
BACKGROUND OF THE MERGER
 
     In September 1991, the  Board of Directors of  Biocraft determined that  it
was  appropriate  to  begin  to  consider  possible  strategic  alternatives for
realizing stockholder value. The Board  was influenced in this determination  by
developing  trends  in, and  affecting,  the pharmaceutical  industry generally.
These included increasing consolidations in  the pharmaceutical industry and  in
the  industries comprising Biocraft's customer base. These trends were viewed as
being affected, in  turn, by actual  and anticipated changes  in government  and
private  health care reimbursement policies and  the drive throughout the health
care industry to achieve greater efficiencies  and cost savings. The Board  also
took  into account the  expressed interest of  Biocraft's founders and principal
stockholders, Harold and Beatrice Snyder, to diversify in an appropriate  manner
their  substantial investment in  Biocraft. Against this  background, it was the
sense of the Board that Biocraft explore the possibility of forming a  strategic
alliance  with another entity through a merger,  an acquisition of Biocraft or a
substantial capital investment in Biocraft by a strategic partner.
 
     To assist it in the evaluation of potential transactions, in November  1991
the Board of Directors of Biocraft authorized the retention of Wertheim Schroder
&  Co., Incorporated ('Wertheim Schroder') as financial advisors to Biocraft. In
the succeeding months,  as Wertheim Schroder  acquainted itself with  Biocraft's
business  and operations it also began, with assistance from Mr. and Mrs. Snyder
and other members of the Snyder  family, to identify U.S. and foreign  companies
that  were  either  involved  in  the pharmaceutical  industry  or  known  to be
exploring acquisitions  or  significant investments  in  the industry  and  that
appeared  to possess the financial and other resources to be able to develop and
expand Biocraft's operations. While this work was ongoing, the Board considered,
among other  matters, the  manner in  which expressions  of interest  should  be
solicited and the timing of such solicitation. Also during this period, Biocraft
received several unsolicited expressions of interest in a strategic transaction.
Mr.  and  Mrs.  Snyder,  with the  assistance  of  Wertheim  Schroder, conducted
exploratory discussions  with  these  parties,  but  none  of  such  discussions
developed into an offer.
 
     On  May 27, 1992,  Biocraft publicly announced that  its Board of Directors
had authorized Wertheim  Schroder to  assist it in  exploring various  strategic
options  in order  to enhance  the value  of Biocraft  to its  stockholders. Its
announcement also stated that  the options being considered  included a sale  of
Biocraft through a merger or other business combination.
 
                                       22
 
<PAGE>
 
<PAGE>
     The  companies  identified  by  Biocraft and  Wertheim  Schroder  were then
contacted by Wertheim  Schroder, on behalf  of Biocraft, to  explore a  possible
strategic   transaction.  Concurrently,  Biocraft  and  Wertheim  Schroder  were
contacted by other  companies that had  become aware of  Biocraft's interest  in
exploring  potential strategic transactions. None of the discussions with any of
such companies progressed beyond the exploratory stage.
 
     In August  1993,  Biocraft  initially  engaged Goldman  Sachs  as  its  new
financial  advisor  in connection  with a  possible  sale of  Biocraft. Biocraft
decided to hire  a financial  advisor in light  of what  management of  Biocraft
perceived   as   an  accelerating   pace  in   consolidations  in   the  generic
pharmaceutical industry at that time.  Biocraft, with the assistance of  Goldman
Sachs,  identified a number of companies that it believed were likely candidates
for a strategic alliance with Biocraft and, along with Goldman Sachs,  commenced
contacting  them. As  in the  earlier period, Biocraft  was, from  time to time,
contacted directly by companies  that had an interest  in exploring a  potential
strategic transaction.
 
     Among  the exploratory  discussions which  Biocraft had  in late  1993 were
discussions with  William Fletcher,  President of  Lemmon Company,  Teva's  U.S.
generic   drug  subsidiary  ('Lemmon').  In   February  1994  these  preliminary
discussions  proceeded  sufficiently  that   Teva  and  Biocraft  entered   into
confidentiality  agreements pursuant to which  confidential information would be
exchanged for the purpose of evaluating a possible transaction.
 
     On the  basis of  the  mutual preliminary  investigation conducted  by  the
companies  through September 1994, in October 1994,  Mr. and Mrs. Snyder and Mr.
Eli Hurvitz, President  and Chief Executive  Officer of Teva,  met to explore  a
possible  merger transaction. Those meetings focused  on a possible stock merger
in which Biocraft would be combined with Teva and in which Biocraft stockholders
would receive Teva Ordinary Shares in the form of Teva ADSs. While no  agreement
was  reached  at  that time  concerning  the  material terms  of  a transaction,
including the rate at which shares  of Biocraft Common Stock would be  converted
in  a merger to Teva ADSs, Mr. and  Mrs. Snyder and Mr. Hurvitz agreed to pursue
further mutual investigation  with the assistance  of advisors and  to begin  to
authorize  counsel for the two companies to  begin developing the form of merger
and associated  agreements pursuant  to which  a transaction  could be  effected
when, as and if further discussions yielded agreement on such material terms.
 
     Mr.  and Mrs. Snyder  met with Mr.  Hurvitz again in  January 1995. At that
time, the discussions related to the possibility of a cash transaction, but were
inconclusive. In May 1995 and again in  September 1995, Mr. and Mrs. Snyder  met
with  Mr. Hurvitz to reconsider a possible stock merger but reached no consensus
on the  material  terms  of  a  transaction.  Significant  fluctuations  in  the
respective  trading  prices  of  the  companies'  securities  and  a  lack  of a
definitive resolution of Biocraft's  ongoing efforts to  establish to the  FDA's
satisfaction  its  compliance  with  FDA's  cGMP  Regulations  hampered  efforts
throughout this  period to  reach  agreement upon  the  relative values  of  the
companies.
 
     During 1994 and 1995, Mr. and Mrs. Snyder and Biocraft's advisors continued
to   have  exploratory  discussions  with  other  potential  strategic  partners
concerning a  range of  transactions, but  none  of such  discussions led  to  a
definitive offer by any of such parties.
 
     On  January 25, 1996 Mr. and Mrs. Snyder  again met with Mr. Hurvitz and on
the basis of negotiations on that day,  agreed to recommend to the Biocraft  and
Teva  Boards, respectively, a merger transaction  at a fixed conversion ratio of
0.461 Teva ADSs for each share of Biocraft Common Stock. On January 28, 1996 and
January 29, 1996, the  Boards of Directors of  Biocraft and Teva,  respectively,
approved the Merger Agreement.
 
RECOMMENDATION OF THE BIOCRAFT BOARD AND BIOCRAFT'S REASONS FOR THE MERGER
 
     At the meeting of the Biocraft Board of Directors held on January 28, 1996,
the  Biocraft Board determined that  the terms of the Merger  are fair to and in
the best  interests of  Biocraft and  its stockholders  and adopted  the  Merger
Agreement  and authorized and  directed the appropriate  officers of Biocraft to
execute the Merger Agreement on behalf of Biocraft.
 
     THE BIOCRAFT BOARD HAS UNANIMOUSLY ADOPTED THE MERGER AGREEMENT, DETERMINED
THAT THE MERGER IS IN THE BEST  INTERESTS OF BIOCRAFT AND ITS STOCKHOLDERS,  AND
RECOMMENDS THAT THE STOCKHOLDERS OF BIOCRAFT VOTE FOR THE APPROVAL OF THE MERGER
AGREEMENT.
 
                                       23
 
<PAGE>
 
<PAGE>
     In  making its  determination, the  Biocraft Board  considered, among other
factors, the opinion received from Goldman Sachs (see ' -- Opinion of  Financial
Advisor'),  the  respective  operating  performances  and  capital  resources of
Biocraft and Teva, and economic and competitive conditions in the industry.  The
Board,  assisted  by  Goldman  Sachs,  also  reviewed  publicly  available  data
concerning Teva and considered reports of interviews with Teva senior management
concerning  Teva's  recent  financial   performance  and  future  plans.   These
considerations  reinforced  the Board's  view  that due  to  increasing industry
competitiveness and Biocraft's limited  capital resources, successful  expansion
of  its  business would  be difficult  and  Biocraft stockholders  might receive
greater long-term  benefits through  a sale  or merger  with a  business  having
greater  capital resources, a broader market  for its products and the potential
for synergistic combination with Biocraft's operations.
 
     Based on  the foregoing,  the Board  concluded that  Teva, because  of  its
greater  size and capital resources, profitable operating performance and strong
competitive position within the industry,  was an attractive merger partner  and
that  the consideration offered in the Merger  was fair and in the best interest
of the stockholders of Biocraft. There can be no assurance, however, that any or
all of  the  objectives  described above  will  be  achieved if  the  Merger  is
consummated.
 
CERTAIN ADVANTAGES AND DISADVANTAGES OF THE
MERGER TO BIOCRAFT AND ITS STOCKHOLDERS
 
     In considering the proposed Merger, the Board of Directors of Biocraft also
considered the following additional actual and potential material advantages and
disadvantages of the Merger to Biocraft and its stockholders:
 
     ADVANTAGES:
 
           More effective selling of Biocraft products as part of a broader line
           of generic drug offerings when combined with those of Lemmon.
 
           Increased utilization of Biocraft's bulk pharmaceutical manufacturing
           capacity  in  connection with  the manufacture  of certain  of Teva's
           dosage form  products  and  the expansion  of  Teva's  existing  bulk
           pharmaceutical chemical product line.
 
           Efficiencies  achievable through the  elimination of certain expenses
           that would be redundant as a result of the Merger.
 
           Greater capital  and other  resources  for, among  other  activities,
           research and development of new generic and other drug products.
 
           No  recognition for Biocraft and its stockholders of any gain or loss
           for tax purposes except with respect to any cash received in lieu  of
           a fractional share interest.
 
           Participation by Biocraft stockholders in the potential future growth
           of a larger enterprise.
 
           Likely greater liquidity for Biocraft stockholders as holders of Teva
           ADSs by virtue of the much larger number of outstanding securities of
           Teva.
 
     DISADVANTAGES:
 
           The  management challenges  presented by  the tasks  of combining the
           operations  of  Biocraft  and  Teva  and  achieving  the  hoped   for
           synergistic benefits.
 
           The  inability of the former stockholders of Biocraft, as a group, to
           control the management of Teva as a result of their minority interest
           in Teva upon completion of the Merger.
 
           The  potential  business  risks  associated  with  Teva's  operations
           outside  the  United  States as  they  may be  affected  by economic,
           political and  military conditions  in those  foreign countries,  and
           currency exchange rate fluctuations and exchange control regulations.
 
TEVA'S REASONS FOR THE MERGER
 
     Teva  believes that the Merger will  substantially broaden both its product
offerings and  its market  presence in  the U.S.  market for  generic drugs  and
enable it to compete more effectively in the rapidly
 
                                       24
 
<PAGE>
 
<PAGE>
changing  market for health care products in  the United States. The U.S. market
for pharmaceutical products is being shaped to an ever greater degree by managed
care  organizations,   pharmaceutical  benefit   managers,  cooperative   buying
organizations  and  large  drug  store  chains.  Teva  believes  that  as  these
organizations increase  in  size,  they  will seek  to  purchase  generic  drugs
directly  from manufacturers who will be able  to supply a broad base of generic
products and establish and  maintain a reputation  for reliability and  service.
The   combination  of  Teva  and  Biocraft   will  create  one  of  the  largest
manufacturers of generic  drugs in  the United  States. Given  that the  product
lines  of the two companies are largely  complementary, the Merger will permit a
consolidated sales force  to offer  a very broad  base of  generic products.  In
addition,  Biocraft's bulk  pharmaceutical production capacity  will both permit
Teva to increase  the extent of  the vertical integration  of its finished  dose
pharmaceutical   production  and  permit  Teva  to  expand  its  worldwide  bulk
pharmaceutical chemical product line.
 
     Teva plans to  cause Biocraft and  Lemmon to  be managed as  a single  unit
under  the  direction of  William Fletcher,  the  President and  Chief Executive
Officer of Lemmon,  and become  part of the  same U.S.  consolidated tax  return
group.  Teva is currently exploring the possibility of eventually merging Lemmon
into Biocraft.
 
OPINION OF FINANCIAL ADVISOR
 
     Goldman Sachs delivered its oral opinion  on January 28, 1996 to the  Board
of Directors of Biocraft that as of such date the Exchange Ratio pursuant to the
Merger  is fair to the holders of Biocraft Common Stock. Goldman Sachs confirmed
its oral opinion by delivery of its  written opinion dated January 29, 1996.  In
addition,  Goldman Sachs subsequently confirmed its earlier opinion  by delivery
of its written opinion dated as of the date hereof.
 
     THE FULL TEXT OF THE WRITTEN OPINION OF GOLDMAN SACHS DATED AS OF THE  DATE
HEREOF, WHICH SETS FORTH ASSUMPTIONS MADE, MATTERS CONSIDERED AND LIMITATIONS ON
THE REVIEW UNDERTAKEN IN CONNECTION WITH THE OPINION, IS ATTACHED AS ANNEX II TO
THIS PROXY STATEMENT/PROSPECTUS AND IS INCORPORATED HEREIN BY REFERENCE. HOLDERS
OF  BIOCRAFT COMMON  STOCK ARE URGED  TO, AND  SHOULD, READ SUCH  OPINION IN ITS
ENTIRETY.
 
     In connection with its opinion, Goldman Sachs reviewed, among other things:
(i) the Registration Statement,  including the Proxy Statement/Prospectus;  (ii)
the Merger Agreement; (iii) Annual Reports to Stockholders and Annual Reports on
Form  10-K of  Biocraft for  the five  years ended  March 31,  1995; (iv) Annual
Reports to Shareholders and  Annual  Reports on  Form  20-F of  Teva for the six
years  ended December 31, 1995; (v)  certain interim reports to stockholders and
Quarterly Reports on Form  10-Q and Reports  on Form 6-K  of Biocraft and  Teva,
respectively;  (vi) certain other communications from Biocraft and Teva to their
respective stockholders;  and  (vii)  certain internal  financial  analyses  and
forecasts  for  Biocraft  and  Teva prepared  by  their  respective managements.
Goldman Sachs also  held discussions with  members of the  senior management  of
Biocraft  and Teva regarding the past and current business operations, financial
condition and future  prospects of  their respective  companies as  well as  the
future  outlook of the combined entity.  In addition, Goldman Sachs reviewed the
reported price and trading activity for  the Biocraft Common Stock and the  Teva
ADSs,  compared certain financial and stock  market information for Biocraft and
Teva with  similar information  for certain  other companies  the securities  of
which  are  publicly  traded, reviewed  the  financial terms  of  certain recent
business combinations  and  performed such  other  studies and  analyses  as  it
considered appropriate.
 
     Goldman Sachs relied without independent verification upon the accuracy and
completeness  of all of the  financial and other information  reviewed by it for
purposes of its opinion. In addition, Goldman Sachs did not make an  independent
evaluation or appraisal of the assets and liabilities of Biocraft or Teva or any
of  their respective subsidiaries and Goldman  Sachs has not been furnished with
any such evaluation  or appraisal. Goldman  Sachs assumed, with  the consent  of
Biocraft's  Board of  Directors, that  the consummation  of the  Merger would be
recorded  as  a  pooling  of  interests  under  generally  accepted   accounting
principles.
 
     The  following is a  summary of certain  of the financial  analyses used by
Goldman Sachs  in connection  with providing  its January  29, 1996  opinion  to
Biocraft's Board of Directors. Goldman Sachs
 
                                       25
 
<PAGE>
 
<PAGE>
used  substantially  the  same type  of  financial analyses  in  connection with
providing the written opinion attached hereto as Annex II.
 
          (i) Historical  Stock Trading  Analysis.  Goldman Sachs  reviewed  the
     historical  trading prices  and volumes for  the Biocraft  Common Stock. In
     addition, Goldman  Sachs  analyzed  the consideration  to  be  received  by
     holders  of  Biocraft  Common Stock  pursuant  to the  Merger  Agreement in
     relation to the  per share closing  price on  the day prior  to the  public
     announcement  of the  Merger (January  26, 1996)  of $13.63.  Such analysis
     indicated that based on  the Exchange Ratio and  the closing price of  Teva
     ADSs  on January  26, 1996 of  $45.25, the  aggregate consideration payable
     pursuant to the Merger represented a premium of 53.1%.
 
          (ii) Selected Companies Analysis. Goldman Sachs reviewed and  compared
     certain   financial  information  relating  to  Biocraft  to  corresponding
     financial  information,  ratios  and  public  market  multiples  for  seven
     publicly  traded corporations:  A.L. pharma, Inc.,  Barr Laboratories Inc.,
     Copley Inc., Forest Laboratories Inc., IVAX Corp., Mylan Laboratories  Inc.
     and  Watson Pharmaceuticals  Inc. (the 'Selected  Companies'). The Selected
     Companies were  chosen  because they  are  publicly traded  companies  with
     operations  that  for purposes  of analysis  may  be considered  similar to
     Biocraft. Goldman Sachs calculated and compared various financial multiples
     and ratios. The  multiples of  Biocraft were  calculated using  a price  of
     $13.63  per share of Biocraft Common Stock, the closing price of the shares
     on the NYSE on the day prior to public announcement of the Merger  (January
     26,  1996). The  multiples and  ratios for Biocraft,  Teva and  each of the
     Selected Companies  were  based  on  the  most  recent  publicly  available
     information.   With  respect  to  the  Selected  Companies,  Goldman  Sachs
     considered levered  market capitalization  (i.e.,  market value  of  common
     equity  plus book value of  debt less cash) as  a multiple of Latest Twelve
     Months ('LTM') sales  and as a  multiple of LTM  earnings before  interest,
     taxes, depreciation and amortization ('EBITDA'). Goldman Sachs' analyses of
     the  Selected Companies  indicated levered  multiples of:  LTM sales, which
     ranged from 0.5x to 5.1x; and LTM EBITDA, which ranged from 9.5x to  36.3x,
     compared to 1.8x and 54.7x, respectively, for Biocraft, and 4.1x and 20.4x,
     respectively,  for  Teva. Goldman  Sachs also  considered for  the Selected
     Companies estimated  calendar  years  1995, 1996  and  1997  price/earnings
     ratios   derived  from  an   aggregation  of  estimates   reported  by  the
     Institutional Broker  Estimate  Service ('IBES')  and  stock prices  as  of
     January  26, 1996, which ranged from  12.6x to 43.9x for estimated calendar
     year 1995, 10.1x  to 32.8x  for estimated calendar  year 1996  and 8.6x  to
     25.5x  for  estimated calendar  year 1997,  compared to  25.7x in  1997 and
     multiples in 1995 and 1996 for  Biocraft which could not be calculated  due
     to  projected losses, and  29.2x, 21.0x and  13.9x, respectively, for Teva;
     and five-year compound annual growth rate of Earnings Per Share ('EPS') for
     the five fiscal years ending in 2001  ranging from 17% to 30%, compared  to
     10% for Biocraft and 25% for Teva.
 
          (iii)  Discounted  Cash  Flow  Analysis.  Goldman  Sachs  performed  a
     discounted cash flow analysis under the following two scenarios: (a)  using
     Biocraft's  management projections  with the  impact of  generic drugs from
     Biocraft's product pipeline (the 'Base Case Plus') and (b) using Biocraft's
     management without the impact  of the generic  drugs in Biocraft's  product
     pipeline (the 'Base Case'). Goldman Sachs calculated a net present value of
     free cash flows for the fiscal years 1997 through 2001 using discount rates
     ranging  from  15% to  25%.  Goldman Sachs  calculated  Biocraft's terminal
     values in the year  2001 based on  multiples ranging from  16x EBIT to  24x
     EBIT.  These terminal  values were then  discounted to  present value using
     discount rates from 15% to 25%.
 
          Goldman Sachs also assumed an annual revenue growth rate of 5% in both
     the Base Case Plus and the Base Case and assumed operating margins of  15%,
     13%  and 11% for estimated fiscal  years 1999, 2000 and 2001, respectively,
     in the Base Case Plus and an assumed operating margin of 10% for  estimated
     fiscal years 1999-2001 in the Base Case. Goldman Sachs, utilizing the above
     analyses,  calculated implied per  share values which  ranged from $8.73 to
     $22.05 in the Base Case Plus and from $5.19 to $16.03 in the Base Case.
 
          In connection with the foregoing, Goldman Sachs also reviewed  certain
     EPS  projections of Biocraft's  management for estimated  fiscal years 1995
     and 1996. The projections reviewed were at various dates from September 14,
     1994   to    December   13,    1995.   Goldman    Sachs   compared    these
 
                                       26
 
<PAGE>
 
<PAGE>
     management projections to actual data, in the case of fiscal year 1995, and
     to  street estimates  reported by  IBES, in the  case of  fiscal year 1996.
     Goldman Sachs' analyses indicated (A)  that management EPS projections  for
     estimated  fiscal year 1995 ranged from  $0.20 per share of Biocraft Common
     Stock on September 14, 1994 to negative $0.20 per share of Biocraft  Common
     Stock  on January 7, 1995, compared to  an actual EPS of negative $0.17 per
     share of Biocraft Common Stock and (B) that management EPS projections  for
     estimated fiscal year 1996 were $1.02 per share of Biocraft Common Stock on
     September  14, 1994, $1.79 per share of Biocraft Common Stock on January 7,
     1995 and negative $0.31 per share of Biocraft Common Stock on December  13,
     1995.
 
          (iv)  Pro  Forma Merger  Analysis.  Goldman Sachs  prepared  pro forma
     analyses of the financial impact of the Merger using earnings estimates for
     Biocraft and Teva prepared  by their respective  managements for the  years
     1996  and  1997  (which were  calendarized  for Biocraft)  (a)  assuming no
     synergies and (b) assuming $15 million of pre-tax synergies. Based on  such
     analyses,   the  proposed   transaction  would   be  accretive   to  Teva's
     shareholders in the years  1996 and 1997, assuming  $15 million of  pre-tax
     synergies   and  in  1997,  assuming   no  synergies,  while  the  proposed
     transaction would be dilutive in 1996, assuming no synergies. Goldman Sachs
     also prepared pro  forma analyses  of the  financial impact  of the  Merger
     using  earnings estimates  for Biocraft and  Teva provided by  IBES for the
     years 1996 and 1997 (calendarized  for Biocraft) (a) assuming no  synergies
     and  (b) assuming $15 million of pre-tax synergies. Based on such analyses,
     the proposed transaction would  be dilutive to  Teva's shareholders in  the
     years 1996 and 1997 (under both scenarios).
 
          (v)  Contribution Analysis. Goldman  Sachs reviewed certain historical
     and estimated future operating and financial information (including,  among
     other  things, sales, EBIT,  net income, book equity  and total assets) for
     Biocraft, Teva and the combined entity  resulting from the Merger based  on
     Biocraft's  and Teva's  managements' financial  forecasts for  Biocraft and
     Teva, respectively. The analysis  indicated that the Biocraft  stockholders
     would receive 10.6% of the outstanding common equity of the combined entity
     after the Merger (based on the number of (i) outstanding shares of Biocraft
     Common  Stock reported  on Biocraft's Quarterly  Report on  Form 10-Q dated
     September 30, 1995 and  (ii) outstanding Teva  Ordinary Shares reported  in
     Teva's  Report on  Form 6-K dated  September 28, 1995).  Goldman Sachs also
     analyzed the relative income statement contribution of Biocraft and Teva to
     the combined entity  on a pro  forma basis based  on estimated years  1995,
     1996 and 1997 (calendarized for Biocraft), based on financial data provided
     to  Goldman Sachs by Biocraft and Teva managements. This analysis indicated
     that in estimated calendar  years 1995, 1996 and  1997 Biocraft would  have
     contributed  18.1%,  16.3%  and  16.1%,  respectively,  to  combined sales,
     negative 1.4%,  11.1%  and  14.3%,  respectively,  to  combined  EBIT,  and
     negative 5.0%, 7.3% and 11%, respectively, to combined net income.
 
     The  preparation of  a fairness  opinion is  a complex  process and  is not
necessarily susceptible to  partial analysis or  summary description.  Selecting
portions  of the analyses or of the summary set forth above, without considering
the analyses  as a  whole, could  create  an incomplete  view of  the  processes
underlying  Goldman Sachs' opinion.  In arriving at  its fairness determination,
Goldman Sachs  considered  the results  of  all  such analyses.  No  company  or
transaction  used in the above analyses as a comparison is identical to Biocraft
or Teva or the contemplated transaction.  The analyses were prepared solely  for
purposes  of  Goldman Sachs'  providing  its opinion  to  the Biocraft  Board of
Directors as  to the  fairness of  the  Exchange Ratio  to the  stockholders  of
Biocraft  and do not purport to be  appraisals or necessarily reflect the prices
at which businesses  or securities  actually may  be sold.  Analyses based  upon
forecasts  of future  results are  not necessarily  indicative of  actual future
results, which may  be significantly more  or less favorable  than suggested  by
such  analyses.  Because such  analyses are  inherently subject  to uncertainty,
being based upon numerous factors or events beyond the control of the parties or
their respective advisors, none  of Biocraft, Teva, Goldman  Sachs or any  other
person  assumes responsibility if  future results are  materially different from
those forecasts. As  described above,  Goldman Sachs'  opinion to  the Board  of
Directors  of Biocraft was one  of many factors taken  into consideration by the
Biocraft Board of Directors  in making its determination  to approve the  Merger
Agreement.  The foregoing summary does not  purport to be a complete description
of the analysis performed by Goldman Sachs  and is qualified in its entirety  by
reference  to the written opinion of Goldman Sachs set forth in Annex II to this
Proxy Statement/Prospectus.
 
                                       27
 
<PAGE>
 
<PAGE>
     Goldman Sachs, as part of  its investment banking business, is  continually
engaged  in the valuation of businesses  and their securities in connection with
mergers  and  acquisitions,  negotiated  underwritings,  competitive   biddings,
secondary  distributions of  listed and unlisted  securities, private placements
and valuations  for  estate, corporate  and  other purposes.  Biocraft  selected
Goldman  Sachs as  its financial advisor  because it is  a nationally recognized
investment banking firm that has substantial experience in transactions  similar
to  the Merger.  Goldman Sachs  is familiar  with Biocraft  having acted  as its
financial advisor in connection with, and having participated in, certain of the
negotiations leading to the Merger Agreement.
 
     Goldman Sachs provides a  full range of  financial, advisory and  brokerage
services  and in the  course of its  normal trading activities  may from time to
time effect transactions  and hold  positions in  the securities  or options  on
securities  of Biocraft and/or Teva  for its own account  and for the account of
customers.
 
     Pursuant to  a letter  agreement  dated January  5, 1995  (the  'Engagement
Letter'),  Biocraft engaged  Goldman Sachs  to act  as its  financial advisor in
connection with  a possible  sale of  Biocraft.  Pursuant to  the terms  of  the
Engagement Letter, Biocraft has agreed to pay Goldman Sachs upon consummation of
the Merger a transaction fee of 1.25% of the aggregate consideration paid in the
Merger (which is to be based on the average of the last sales price for Biocraft
Common Stock on the five trading days ending five days prior to the consummation
of  the  Merger).  Biocraft  has  agreed  to  reimburse  Goldman  Sachs  for its
reasonable out-of-pocket expenses, including reasonable attorneys' fees, and  to
indemnify   Goldman  Sachs   against  certain   liabilities,  including  certain
liabilities under the United States Federal securities laws.
 
EFFECTIVE TIME
 
     The Merger will become effective at such time as a Certificate of Merger is
duly filed with  the Secretary of  State of the  State of Delaware,  or at  such
other  time as Teva and Biocraft agree  should be specified in such certificate.
The Merger Agreement provides that Merger Sub and Biocraft will execute and file
such certificate or other appropriate documents as soon as practicable after the
last of the  conditions to the  Merger have  been fulfilled. See  'TERMS OF  THE
MERGER AGREEMENT -- Conditions to the Merger'.
 
EXCHANGE RATIO
 
     At  the  Effective Time,  each share  of Biocraft  Common Stock  issued and
outstanding immediately  prior  to the  Effective  Time, other  than  shares  of
Biocraft  Common Stock owned by Biocraft in the form of treasury shares, will be
converted into the right  to receive that number  of validly issued, fully  paid
and  nonassessable  Teva ADSs  representing Teva  Ordinary  Shares equal  to the
Exchange Ratio.
 
     As of the  Effective Time,  all shares of  Biocraft Common  Stock shall  no
longer  be outstanding and shall automatically be canceled and retired and shall
cease to exist, and each holder of a certificate representing any such shares of
Biocraft Common  Stock shall  cease to  have any  rights with  respect  thereto,
except  the right to receive Teva ADSs representing Ordinary Shares and any cash
in lieu of fractional Teva ADSs to  be issued or paid in consideration  therefor
upon  surrender of such certificate, in each case without interest. Any treasury
shares of Biocraft Common Stock will  automatically be canceled and retired  and
will cease to exist as of the Effective Time.
 
EXCHANGE AGENT; EXCHANGE PROCEDURES; DISTRIBUTIONS WITH RESPECT TO UNEXCHANGED
SHARES; NO FURTHER OWNERSHIP RIGHTS IN BIOCRAFT COMMON STOCK; NO FRACTIONAL TEVA
ADSS
 
     Exchange  Agent. The  Merger Agreement requires  Teva to deposit  as of the
Effective Time,  with The  Bank of  New  York (the  'Exchange Agent'),  for  the
benefit  of the holders of shares of Biocraft Common Stock, Teva Ordinary Shares
to be represented by Teva ADSs issuable in exchange for Biocraft Common Stock.
 
     Exchange Procedures. As soon as reasonably practicable after the  Effective
Time,  Teva shall cause the Exchange Agent to mail to each holder of record of a
certificate or  certificates  which  immediately prior  to  the  Effective  Time
represented    outstanding    shares    of    Biocraft    Common    Stock   (the
 
                                       28
 
<PAGE>
 
<PAGE>
'Certificates'), whose shares were converted into the right to receive Teva ADSs
pursuant to the Merger,  (i) a letter of  transmittal (which shall specify  that
delivery shall be effected, and risk of loss and title to the Certificates shall
pass, only upon delivery of the Certificates to the Exchange Agent, and shall be
in  such form and have such other provisions as Teva may reasonably specify) and
(ii) instructions for  use in  effecting the  surrender of  the Certificates  in
exchange  for ADRs representing  Teva ADSs. Upon surrender  of a Certificate for
cancellation to the Exchange  Agent, together with  such letter of  transmittal,
duly  executed, and such  other documents as  may reasonably be  required by the
Exchange Agent, the holder of such  Certificate shall be entitled to receive  in
exchange  therefor an  ADR representing Teva  ADSs (rounded down  to the nearest
whole Teva ADS) which  such holder has  the right to  receive after taking  into
account  all the shares of Biocraft Common  Stock then held by such holder under
all such Certificates so surrendered, cash  in lieu of fractional Teva ADSs  and
any  dividends or other distributions to which  such holder is entitled, and the
Certificate so  surrendered shall  forthwith  be canceled.  In  the event  of  a
transfer  of ownership of  Biocraft Common Stock  that is not  registered in the
transfer records of Biocraft, an ADR representing  Teva ADSs may be issued to  a
person  other than the  person in whose  name the Certificate  so surrendered is
registered, if, upon  presentation to  the Exchange Agent,  such Certificate  is
properly  endorsed or otherwise  is in proper  form for transfer  and the person
requesting such payment pays any transfer  or other taxes required by reason  of
the  issuance of Teva ADSs to a person  other than the registered holder of such
Certificate or establishes to  the satisfaction of Teva  that such tax has  been
paid  or  is not  applicable. Until  so surrendered,  each Certificate  shall be
deemed at any  time after  the Effective  Time to  represent only  the right  to
receive  upon such surrender an ADR representing  Teva ADSs, cash in lieu of any
fractional Teva ADSs  and any  dividends or  other distributions  to which  such
holder is entitled pursuant to the Merger Agreement. No interest will be paid or
will accrue on any cash payable pursuant to the Merger Agreement.
 
     BIOCRAFT STOCKHOLDERS SHOULD NOT FORWARD BIOCRAFT STOCK CERTIFICATES TO THE
EXCHANGE AGENT UNTIL THEY HAVE RECEIVED TRANSMITTAL FORMS. BIOCRAFT STOCKHOLDERS
SHOULD NOT RETURN STOCK CERTIFICATES WITH THE ENCLOSED PROXY.
 
     Distributions  with Respect  to Unexchanged  Shares. No  dividends or other
distributions with respect to Teva Ordinary Shares with a record date after  the
Effective Time shall be paid to the holder of any unsurrendered Certificate with
respect  to the  Teva ADSs represented  thereby and  no cash payment  in lieu of
fractional Teva ADSs shall be paid to any such holder until the holder of record
of such Certificate shall surrender such Certificate. Following surrender of any
such Certificate,  there  shall  be  paid  to the  record  holder  of  the  ADRs
representing Teva ADSs issued in exchange therefor, without interest, (i) at the
time  of such surrender, the amount of any  cash payable in lieu of a fractional
Teva ADS and the amount of dividends  or other distributions with a record  date
after  the Effective Time theretofore paid with respect to such whole Teva ADSs,
and (ii)  at the  appropriate payment  date, the  amount of  dividends or  other
distributions  with a record  date after the  Effective Time, but  prior to such
surrender, and a payment date subsequent to such surrender payable with  respect
to such whole Teva ADSs.
 
     No  Further Ownership Rights in Biocraft Common Stock. All Teva ADSs issued
upon the surrender for exchange of shares of Biocraft Common Stock in accordance
with the terms of the Merger Agreement (including any cash paid) shall be deemed
to have been issued in full satisfaction of all rights pertaining to such shares
of Biocraft  Common  Stock,  and  there shall  be  no  further  registration  of
transfers on the stock transfer books of the Surviving Corporation of the shares
of  Biocraft  Common  Stock  which were  outstanding  immediately  prior  to the
Effective Time. If, after the Effective Time, Certificates are presented to  the
Surviving  Corporation  or the  Exchange  Agent for  any  reason, they  shall be
canceled and exchanged as provided in the Merger Agreement.
 
     No Fractional Teva ADSs. No ADRs representing fractional Teva ADSs shall be
issued upon the surrender for exchange of Certificates. Each holder of shares of
Biocraft Common Stock exchanged pursuant to the Merger who would otherwise  have
been entitled to receive a fraction of a Teva ADS (after taking into account all
Certificates  delivered  by such  holder) will  receive,  in lieu  thereof, cash
(without interest)  in  an  amount equal  to  such  stockholder's  proportionate
interest in the net proceeds
 
                                       29
 
<PAGE>
 
<PAGE>
from  the  sale by  the Exchange  Agent on  behalf  of all  such holders  of the
aggregate of the fractions of ADSs which would otherwise be issued.
 
ADMISSION FOR TRADING ON NASDAQ NATIONAL MARKET
 
     Teva ADSs are presently admitted for trading on the NASDAQ National Market.
It is a condition to each party's obligation to effect the Merger that the  Teva
ADSs  issuable to Biocraft's stockholders pursuant to the Merger Agreement shall
have been  admitted  for trading  on  the  NASDAQ National  Market,  subject  to
official notice of issuance. See 'TERMS OF THE MERGER AGREEMENT -- Conditions to
the Merger'.
 
CESSATION OF NYSE TRADING AND DEREGISTRATION OF BIOCRAFT COMMON STOCK AFTER THE
MERGER
 
     If  the Merger is consummated,  the Biocraft Common Stock  will cease to be
traded on the NYSE and will be  deregistered under the Exchange Act. After  such
delisting  and  deregistration,  Biocraft  will  no  longer  be  subject  to any
reporting obligations under the Exchange Act.
 
CERTAIN SIGNIFICANT CONSIDERATIONS
 
     In considering whether to approve and adopt the Merger Agreement  providing
for the Merger, stockholders of Biocraft should carefully consider those factors
described  under 'RISK FACTORS' as  well as the fact  that the Exchange Ratio is
fixed and will not be adjusted based on  changes in the price of the Teva  ADSs,
and  the price of the Teva ADSs at the Effective Time may vary from the price as
of the date of this Proxy Statement/Prospectus or the date on which stockholders
of Biocraft vote on  the Merger due  to changes in  the business, operations  or
prospects  of Teva, market assessments of the likelihood that the Merger will be
consummated and the timing thereof, general market and economic conditions,  and
other factors.
 
CERTAIN TAX CONSEQUENCES OF THE MERGER
 
     The  Merger is intended to be a 'tax-free reorganization' for United States
Federal income tax purposes under section 368(a)(1)(A) and section  368(a)(2)(E)
of the Internal Revenue Code of 1986, as amended (the 'Code'). As a consequence:
 
          1.  Neither Teva, Merger  Sub nor Biocraft will  recognize any gain or
     loss in the Merger.
 
          2. A holder  of Biocraft Common  Stock who, in  the Merger,  exchanges
     shares  of Biocraft Common Stock for Teva  ADSs will not recognize any gain
     or loss upon  such exchange, except  that (as noted  in paragraph 5  below)
     gain  or loss may be recognized with respect  to cash received in lieu of a
     fractional share interest. However, a United States resident or citizen  or
     domestic  corporation  that owns  (directly, indirectly  or constructively)
     Teva ADSs  and Teva  Ordinary  Shares representing  in the  aggregate  five
     percent  or more of the Teva  Ordinary Shares outstanding immediately after
     the Effective Time may have to  recognize gain under section 367(a) of  the
     Code  unless certain requirements relating  to a gain recognition agreement
     with the Internal Revenue Service are satisfied.
 
          3. The aggregate adjusted tax basis of the Teva ADSs received in  such
     exchange  (including  a  fractional  share  interest  deemed  received,  as
     explained in paragraph 5 below) will be equal to the aggregate adjusted tax
     basis of the shares of Biocraft Common Stock surrendered therefor.
 
          4. If the shares of Biocraft  Common Stock are held as capital  assets
     at the Effective Time, the holding period of the Teva ADSs will include the
     holding period of the shares of Biocraft Common Stock exchanged therefor.
 
          5.  A holder of shares  of Biocraft Common Stock  who receives cash in
     the Merger in  lieu of  a fractional  Teva ADS  will be  treated as  having
     received  such fractional share  in such exchange  and then having received
     cash in redemption of such fractional  share interest by Teva. The  receipt
     of  such cash should cause the recipient to recognize capital gain or loss,
     provided  the  shares  of  Biocraft  Common  Stock  surrendered  for   such
     fractional  share interest  were held  as capital  assets at  the Effective
     Time, equal to the difference between  the amount of cash received and  the
     portion of
 
                                       30
 
<PAGE>
 
<PAGE>
     such  holder's adjusted  tax basis in  the shares of  Biocraft Common Stock
     allocable to the fractional share interest.
 
     The obligations of the parties to consummate the Merger are subject to  the
receipt  by Biocraft of an opinion of its  counsel and the receipt by Teva of an
opinion of its counsel, each to the  effect that the Merger will be a  'tax-free
reorganization'  for  United States  Federal income  tax purposes  under section
368(a) of the Code. Each such opinion is based on current law and various  other
assumptions as set forth in the copies of such opinions filed as exhibits to the
Registration Statement of which this Proxy Statement/Prospectus forms a part.
 
     THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY
AND  IS BASED UPON PRESENT UNITED  STATES FEDERAL LAW. EACH BIOCRAFT STOCKHOLDER
SHOULD CONSULT HIS OR HER TAX ADVISOR AS TO THE SPECIFIC TAX CONSEQUENCES OF THE
MERGER TO HIM  OR HER,  INCLUDING THE APPLICATION  AND EFFECT  OF UNITED  STATES
FEDERAL,  STATE, LOCAL, FOREIGN AND  OTHER TAX LAWS AND  THE POSSIBLE EFFECTS OF
CHANGES IN UNITED STATES FEDERAL LAW OR OTHER TAX LAWS. THE FOREGOING DISCUSSION
MAY NOT BE APPLICABLE WITH  RESPECT TO TEVA ADSS  RECEIVED BY CURRENT OR  FORMER
BIOCRAFT  EMPLOYEES IN  THE MERGER  THROUGH THE  OPERATION OF  BIOCRAFT EMPLOYEE
STOCK OPTION PLANS.
 
ANTICIPATED ACCOUNTING TREATMENT
 
     The Merger is designed to qualify as 'pooling-of-interests' for  accounting
and  financial reporting purposes. Under this method of accounting, the recorded
assets and liabilities of Biocraft and Teva  will be carried forward to Teva  at
their  recorded amounts; income of Teva will include income of Teva and Biocraft
for the entire fiscal year in which  the Merger occurs; and the reported  income
of  the separate corporations for prior periods will be combined and restated as
income of the  combined company. The  obligations of the  parties to the  Merger
Agreement  to consummate  the Merger  are subject  to the  receipt by  Teva from
Kesselman & Kesselman, the  independent auditors of Teva,  and by Biocraft  from
Ernst  & Young LLP, the independent auditors of Biocraft, of their opinions that
there is no fact or circumstance known  to them concerning Teva and Merger  Sub,
on the one hand, or Biocraft, on the other hand, respectively, which would cause
the    Merger   not   to   be   recorded    for   accounting   purposes   as   a
'pooling-of-interests'. See 'TERMS OF THE MERGER AGREEMENT -- Conditions to  the
Merger'.
 
ABSENCE OF APPRAISAL RIGHTS
 
     Holders  of Teva Ordinary  Shares will not be  entitled to appraisal rights
under Israeli law in connection with the Merger.
 
     Delaware law  does not  provide a  stockholder with  appraisal rights  with
respect  to any  merger in which  holders of stock  traded on the  NYSE are only
required to accept for  such stock shares  of stock of  a corporation which  are
traded  on the NASDAQ National Market. Teva ADSs are, and it is anticipated will
be at the  Effective Time, traded  on the NASDAQ  National Market.  Accordingly,
Biocraft  stockholders will not  be entitled to  appraisal rights under Delaware
law  in   connection   with  the   Merger.   See  'COMPARISON   OF   STOCKHOLDER
RIGHTS -- Appraisal Rights'.
 
IRREVOCABLE PROXY AND TERMINATION RIGHTS AGREEMENT
 
     As  an inducement  for Teva  to enter  into the  Merger Agreement,  each of
Harold  Snyder,  Biocraft's  current  Chairman,  Chief  Executive  Officer   and
President,  Beatrice  Snyder,  Biocraft's  current  Senior  Vice  President  and
Secretary, and their children as trustees for certain trusts which Mr. and  Mrs.
Snyder  have  established, holding  in the  aggregate  approximately 60%  of the
outstanding shares of Biocraft Common Stock, has executed the Irrevocable  Proxy
whereby,  among other things, such stockholder has irrevocably appointed Teva as
agent, attorney and proxy to vote such stockholder's shares (i) in favor of  the
Merger,  (ii)  in favor  of  the Merger  Agreement,  (iii) against  any Takeover
Proposal (as defined in the Merger  Agreement) (other than the Merger) or  other
proposal  which  provides  for any  merger,  sale  of assets  or  other business
combination between  Biocraft and  any other  person or  entity or  which  would
 
                                       31
 
<PAGE>
 
<PAGE>
make it impractical for Teva to effect a merger or other business combination of
Biocraft  with Teva or  a wholly owned  subsidiary of Teva  and (iv) against any
other action  or  agreement that  would  result in  a  breach of  any  covenant,
representation  or warranty  or any  other obligation  or agreement  of Biocraft
under  the  Merger  Agreement  or  which  could  result  in  any  of  Biocraft's
obligations under the Merger Agreement not being fulfilled.
 
     In  addition, pursuant to the Irrevocable Proxy, if the Merger Agreement is
terminated in certain specified circumstances and  a stockholder who is a  party
to   the  Irrevocable  Proxy  sells  or   otherwise  disposes  of  any  of  such
stockholder's Biocraft Common Stock  pursuant to a  Third Party Acquisition  (as
defined in the Merger Agreement), then, such stockholder is obligated to pay, or
cause  to  be paid,  in  same day  funds  (to the  extent  of cash  received and
otherwise payable in  kind) to  Teva upon  demand an  amount equal  to (x)  such
stockholder's  Profit per Share multiplied by (y) the aggregate number of shares
of Biocraft Common Stock sold or  otherwise disposed of by such stockholder.  As
used  in the Irrevocable Proxy, 'Profit per  Share' in connection with a sale or
other disposition of shares of Biocraft Common Stock by a stockholder means on a
per share basis the  amount by which (A)  the sum of (1)  if such sale or  other
disposition  is for  or made in  cash, the  cash received by  the stockholder in
respect of  each share  of Biocraft  Common Stock,  (2) if  such sale  or  other
disposition  is for or made  in marketable securities, the  fair market value at
the time  such securities  are received  by the  stockholder of  the  securities
received  in respect of each share of Biocraft Common Stock, (3) if such sale or
other disposition  is for  or made  in property  other than  cash or  marketable
securities,  the fair market value at the  time such property is received by the
stockholder of the property received in respect of each share of Biocraft Common
Stock (or any combination of the  consideration referred to in clauses (1),  (2)
and (3)), and (4) without duplication, any dividends or interest received by the
stockholder  in respect of each  share of Biocraft Common  Stock exceeds (B) the
higher of the fair market  value of 0.461 Teva ADSs  on January 29, 1996 and  on
the  date that  the Merger  Agreement is terminated.  As used  therein, the term
'fair market value'  means, in the  case of marketable  securities, the  closing
sale  price of the security  on the principal securities  exchange on which such
security is listed,  if such security  is listed  on any such  exchange, or  the
closing  bid quotation with respect to  the security on the National Association
of Securities Dealers, Inc.  automated quotations system  or any similar  system
then in general use, if such quotations are available, and, in the case of other
property, the fair market value thereof as agreed to by the parties, or, if they
are  unable to agree, as  determined by a third  party appraiser selected by the
parties.
 
     The Irrevocable Proxy will terminate on  the earlier of the Effective  Time
or 24 months following the date of termination of the Merger Agreement, provided
that  the appointment of Teva  as agent, attorney and  proxy will terminate upon
the termination of the Merger Agreement.
 
INTERESTS OF CERTAIN PERSONS IN THE MERGER
 
     Directors and Officers of the Surviving Corporation. At the Effective Time,
the Board of  Directors of  the Surviving  Corporation will  consist of:  Harold
Snyder,  Biocraft's  current Chairman,  Chief  Executive Officer  and President;
Beatrice Snyder, Biocraft's  current Senior  Vice President  and Secretary;  Eli
Hurvitz,  the President and  Chief Executive Officer  of Teva; William Fletcher,
the President and Chief Executive Officer of Lemmon; Peter H. Jakes, U.S.  legal
counsel  to Teva; and  Elon Kohlberg, a professor  of business administration at
Harvard University.  Each  such director  will  hold  office until  his  or  her
successor  is  duly  appointed and  qualified.  At the  Effective  Time, William
Fletcher will serve as  President and Chief Executive  Officer of the  Surviving
Corporation,  and Peter Terreri,  Vice President and  Chief Financial Officer of
Lemmon, will serve  as Vice  President, Chief Financial  Officer and  Treasurer.
Pursuant  to the employment  agreements referred to below  under ' -- Employment
Agreements', Harold  Snyder will  serve as  Senior Vice  President and  Beatrice
Snyder  will  serve  as Vice  President  --  Cost Accounting  and  Inventory and
Secretary of the Surviving  Corporation. Harold Snyder  and Beatrice Snyder  are
husband  and wife. Other current officers will  continue to serve as officers of
the Surviving Corporation at the discretion of the Board.
 
     Representation on the  Board of Teva.  The Board of  Directors of Teva  has
adopted  a resolution nominating  Harold Snyder for election  at the next annual
meeting following the  Effective Time  as a director  of Teva  for a  three-year
term,   recommending   that   upon   his   election   to   the   Board,   he  be
 
                                       32
 
<PAGE>
 
<PAGE>
designated  as  a  member  of  the  Executive  Committee  of  Teva's  Board  and
recommending  to  the Board  as reconstituted  after each  of the  following two
annual meetings to continue to designate Mr. Snyder as a member of the Executive
Committee while he continues to serve  on the Teva Board. In addition,  pursuant
to  the  terms of  Teva's Articles  of  Association, the  Snyder family  will be
entitled to appoint a director of Teva  by virtue of their holding in excess  of
4%  of Teva's outstanding share capital. The Snyder family has advised Teva that
they intend to select Beatrice Snyder to serve as this director.
 
     Employment Agreements.  The  Surviving  Corporation will,  as  a  condition
precedent   to  the  Merger,  execute  employment  agreements  (the  'Employment
Agreements') with Harold Snyder and  Beatrice Snyder (each, an 'Executive'),  to
take  effect at  the Effective  Time. The  Employment Agreements  provide for an
employment term of  three years  from the  Effective Time.  The Executives  will
continue  to receive their current  annual base salary ($500,000  in the case of
Harold Snyder and $173,414 in the  case of Beatrice Snyder). If the  Executive's
employment  is terminated prior to the expiration  of the three-year term by the
Surviving Corporation other than as a result  of the death or disability of  the
Executive or for 'Cause' (as such term is defined in the Employment Agreements),
the  Surviving Corporation is obligated to pay  the Executive an amount equal to
the Executive's unearned base salary for the remainder of the three-year term of
the applicable Employment  Agreement. In addition,  if the Executive  terminates
employment  for  'Good  Reason'  (as  such term  is  defined  in  the Employment
Agreements), the  Executive is  also entitled  to payment  of such  amount.  The
Executive  will be  entitled to participate  in, or receive  benefits under, any
employee benefit plan, arrangement or perquisite generally made available by the
Surviving Corporation during the three-year term of the Employment Agreements to
its executives and key management employees.
 
     Severance and  Indemnification.  The  Merger  Agreement  provides  for  the
payment  of certain  severance benefits to  executive officers  and employees of
Biocraft.  In  addition,  pursuant  to   the  Merger  Agreement  the   Surviving
Corporation  will maintain, for a period of  six years after the Effective Time,
certain rights  to indemnification  in favor  of present  and former  directors,
officers  and  employees of  Biocraft. See  'THE  MERGER --  Severance Payments;
Effect on Employee Benefit and Stock Option Plans; Indemnification'.
 
OPERATIONS AFTER THE MERGER
 
     At the Effective Time,  Merger Sub will be  merged with and into  Biocraft,
and  Biocraft, as the Surviving Corporation in  the Merger, will become a wholly
owned subsidiary of Teva. Teva plans  to cause Biocraft and Lemmon, Teva's  U.S.
generic  drug subsidiary, to be managed as  a single unit under the direction of
William Fletcher,  the President  and  Chief Executive  Officer of  Lemmon,  and
become  part of the same  U.S. consolidated tax return  group. Teva is currently
exploring the possibility of eventually merging Lemmon into Biocraft.
 
     Neither Teva  nor  Biocraft  has  any present  plans  for  dispositions  of
material  assets. There can be no assurance,  however, that in the future either
Teva or Biocraft,  or both, may  not deem  it advisable to  dispose of  material
assets.  Pursuant to the terms of the  Merger Agreement, however, Teva will not,
(i) after  the  Effective  Time, make  any  disposition  of the  assets  of  the
Surviving  Corporation or any equity interest in the Surviving Corporation which
would  prevent  the  Merger  from  being  recorded  as  a  pooling  of  interest
transaction  or (ii) prior  to the third  anniversary of the  Effective Time (or
under certain circumstances the fifth anniversary), make any disposition of  the
assets  of the  Surviving Corporation that  would cause any  recognition of gain
under a gain  recognition agreement  with the  Internal Revenue  Service by  any
former  Biocraft shareholder who is a  'five percent transferee shareholder' (as
defined  in  the  U.S.  Treasury  regulations),  except  in  certain   specified
circumstances.
 
     Teva  has in the past paid cash dividends. The payment and amount of future
dividends, if any, will  be determined by the  Teva Board based upon  conditions
then  existing, including Teva's earnings, if  any, and financial condition, tax
expense, capital requirements and other relevant factors.
 
EFFECT ON DIVIDEND REINVESTMENT PLAN
 
     Biocraft has, pursuant  to the Merger  Agreement, amended the  Stockholders
Dividend  Reinvestment  and Stock  Purchase Plan  to terminate  the supplemental
payment investment option offered
 
                                       33
 
<PAGE>
 
<PAGE>
thereunder. Teva  does  not have  a  comparable plan;  accordingly  no  dividend
reinvestment  plan will be  available following the Merger  to former holders of
Biocraft Common Stock.
 
SEVERANCE PAYMENTS; EFFECT ON EMPLOYEE BENEFIT AND STOCK OPTION PLANS;
INDEMNIFICATION
 
     Severance Payments. The Merger Agreement provides that Teva will cause  the
Surviving  Corporation to adopt  a severance plan providing  for payment to each
Biocraft employee, whose tenure and conditions of employment are not covered  by
a collective bargaining agreement, and whose employment is terminated within one
year after the Effective Time a severance benefit in cash in an amount equal to:
(i)  in the case of  Vice Presidents and Assistant  Vice Presidents of Biocraft,
twelve (12) months base salary, payable in equal monthly installments, and  (ii)
in  the case of  other non-union employees, such  employee's regular weekly base
pay multiplied by the number of years  of employment such employee has had  with
Biocraft  up to ten (10) years of  employment, plus two times such weekly salary
multiplied by the number of years of such employment beyond the tenth year (such
payment to be paid  on a weekly  basis in an amount  not exceeding such  regular
weekly  base pay, and reduced by  any applicable withholding and payroll taxes).
The Surviving Corporation, however, is  free to include customary provisions  in
such  severance plan  including, without  limitation, provisions  which preclude
payment in the  event of  a termination  for cause and  payment as  a result  of
inter-plant  transfers among Biocraft's New Jersey facilities. Any such employee
whose employment is terminated after the first anniversary of the Effective Time
will be  entitled  to  the same  severance  benefits  as are  payable  to  other
non-union employees of Teva's U.S. generic drug subsidiary.
 
     Employee  Benefit Plans. The Merger Agreement further provides that, at the
Effective Time, subject to applicable law, all of the Employee Benefit Plans (as
defined therein) as  of the  date of  the closing  of the  Merger (the  'Closing
Date'),  other than those  involving stock of  Biocraft ('Current Benefits') and
all employment agreements between Biocraft and any of its employees in effect as
of the Closing Date will continue, and for not less than one year from and after
the Closing  Date,  Teva  will  provide  for  the  employees  of  the  Surviving
Corporation  to  continue  to participate  in  the  Current Benefits  and  to be
provided aggregate benefits  thereunder that  are not less  than those  provided
thereunder during Biocraft's most recent fiscal year. Teva may effect any change
after  such one-year period on a prospective  basis in any Employee Benefit Plan
or Pension Plan (as defined therein)  or terminate such plans, provided that  to
the extent it terminates any Employee Benefit Plan after the Effective Time, and
any  U.S. generic drug subsidiary of Teva  has in place a benefit plan providing
benefits of the same general type as the terminated Employee Benefit Plan to its
similarly situated  subsidiaries' employees,  Teva  will thereafter  permit  the
employees  of the Surviving Corporation to  participate in such employee benefit
plan of its U.S. subsidiary or a similar plan.
 
     Stock Option Plans. Certain officers,  directors and employees of  Biocraft
have  received  options to  acquire Biocraft  Common Stock  ('Biocraft Options')
pursuant to the  Biocraft Incentive Stock  Option Plan and  the 1987  Directors'
Stock  Option  Plan  (the  'Biocraft  Stock  Plans').  Pursuant  to  the  Merger
Agreement, prior to  the Effective Time  the Biocraft Board  will terminate  the
Biocraft  Stock Plans and each holder of Biocraft Options pursuant to such plans
will, in accordance with  the terms of  his or her  option agreements, have  the
right  to exercise,  by written  notice, all such  options, whether  or not then
exercisable by the terms of the applicable option agreement. Options as to which
no notice of exercise is received by  Biocraft will be converted into the  right
to  receive promptly  after the  Effective Time,  as to  each share  of Biocraft
Common Stock covered thereby (without regard to any then applicable restrictions
on the exercise  of such options),  the number  of Teva ADSs  determined by  (i)
multiplying  the Exchange Ratio  by the fair market  value of a  Teva ADS on the
Effective Date, (ii) subtracting from the product of such multiplication the sum
of the applicable per share exercise price plus applicable per share withholding
for taxes (which will be appropriately remitted to the applicable tax  authority
on  behalf of such  optionee) and (iii)  dividing the amount  obtained in clause
(ii) by the fair market value of an ADS on the Effective Date. For such purpose,
the fair market value of a Teva ADS on the NASDAQ National Market shall mean the
average of the last sale prices of a Teva  ADS on the NASDAQ on each of the  ten
trading  days ending two trading days prior  to the Effective Date. In addition,
prior to the Effective Time, but subject to the Merger, the Biocraft Board  will
cause  Biocraft's Restricted  Stock Purchase Plan  to be amended  to (a) provide
that no further restricted stock grants be
 
                                       34
 
<PAGE>
 
<PAGE>
made after the Effective Time and (b)  provide that the terms and conditions  of
such  Plan will apply to the Teva ADSs  and Teva Ordinary Shares issued upon the
Merger to the  holders of  restricted stock under  such Plan,  and such  holders
shall  thereafter hold such  Teva ADSs and  Teva Ordinary Shares  subject to the
terms and conditions of such Plan, including without limitation any  requirement
for the legending of certificates evidencing such securities.
 
     The  following  table  sets  forth  with respect  to  each  of  the current
directors of Biocraft  and all  executive officers thereof  as a  group (i)  the
number  of shares of Biocraft Common Stock subject to stock options held by them
as of April 22, 1996, (ii) the number of shares subject to options held by  them
that  had not vested prior to April 22, 1996 (all of which will be automatically
vested and immediately exercisable at the Effective Time) and (iii) the  average
exercise  price per share of Biocraft Common Stock subject to such stock options
as of April 22, 1996.
 
<TABLE>
<CAPTION>
                                                                                NUMBER OF SHARES OF
                                                                                  BIOCRAFT COMMON
                                                         NUMBER OF SHARES OF     STOCK SUBJECT TO
                                                           BIOCRAFT COMMON       OPTIONS THAT HAD         AVERAGE
                                                            STOCK SUBJECT        NOT VESTED BEFORE     EXERCISE PRICE
                         NAME                                TO OPTIONS           APRIL 22, 1996         PER SHARE
- ------------------------------------------------------   -------------------    -------------------    --------------
<S>                                                      <C>                    <C>                    <C>
Beryl Snyder..........................................          13,350               --                    $ 8.75
Brian Snyder..........................................          12,450               --                      9.02
Jay Snyder............................................          12,450               --                      9.02
All executive officers and directors as a group.......         117,400                 1,850               $10.25
</TABLE>
 
     Indemnification of Directors and Officers Pursuant to the Merger Agreement.
Pursuant to the Merger Agreement, for a period of six years after the  Effective
Time,  the Surviving Corporation  will, subject to  applicable law, maintain all
rights to indemnification  existing on the  date of the  Merger Agreement  under
Biocraft's  Certificate of Incorporation and By-laws in favor of the present and
former directors, officers  and employees  of Biocraft with  respect to  matters
occurring  prior to the Effective Time,  and Teva has guaranteed the performance
in full of such indemnification  obligations of the Surviving Corporation.  Teva
has  agreed  to use  its  best efforts  to  cause the  Surviving  Corporation to
maintain for  three years  from  the Effective  Time,  the current  policies  of
directors'  and officers'  liability insurance  maintained by  Biocraft covering
those persons who are currently  covered by Biocraft's directors' and  officers'
liability   insurance  policy,  provided  that  the  Surviving  Corporation  may
substitute therefor policies of at least  the same coverage containing terms  no
less  advantageous to such  directors, officers and  employees and the Surviving
Corporation is not required to pay an annual premium therefor in excess of  150%
of  the last  annual premium paid  by Biocraft prior  to the date  of the Merger
Agreement ('Biocraft's Current Premium'). If such premiums for such insurance at
any  time  exceed  150%  of  Biocraft's  Current  Premium,  then  the  Surviving
Corporation  will cause  to be  maintained policies  of insurance  which, in the
Surviving Corporation's good faith  determination, provide the maximum  coverage
available  at an annual premium equal to  150% of Biocraft's Current Premium and
the indemnified  parties  have the  right  to  provide funds  to  the  Surviving
Corporation  to  fund premiums  to  the extent  they  exceed 150%  of Biocraft's
Current Premium.
 
REGULATORY FILINGS AND APPROVALS
 
     Antitrust. The Merger is subject to the requirements of the HSR Act and the
rules and regulations  thereunder, which provide  that certain transactions  may
not  be consummated until required information and materials have been furnished
to the Antitrust Division and the  FTC and certain waiting periods have  expired
or  been  terminated.  Teva  and Biocraft  filed  the  required  information and
materials with  the Antitrust  Division and  the  FTC on  March 1,  1996.  Early
termination  of the statutory  waiting period under  the HSR Act  was granted on
March 28, 1996.
 
     The Antitrust Division and the FTC frequently scrutinize the legality under
the antitrust laws of  transactions such as  the Merger. At  any time before  or
after  the Effective Time, either  the Antitrust Division or  the FTC could take
such action under the antitrust laws as  it deems necessary or desirable in  the
public  interest, or certain other persons could take action under the antitrust
laws, including seeking to enjoin the Merger.
 
     Israeli Regulatory Approvals. The consummation of the Merger is conditioned
upon (i) there being in effect the consent of the Controller of Foreign Currency
to the Merger, the issuance of Teva Ordinary
 
                                       35
 
<PAGE>
 
<PAGE>
Shares and  certain of  the  transactions contemplated  in connection  with  the
Merger,  (ii)  Teva  having  received  the  required  permit  from  the  Israeli
Securities Authority to publish  a prospectus in connection  with the Merger  or
having  obtained  an  exemption  from  such  requirement  and  (iii)  consent in
principle having been granted by the TASE to list the Teva Ordinary Shares to be
issued in  connection with  the Merger.  Teva has  obtained the  consent of  the
Controller  of Foreign Currency to the Merger, the issuance of the Teva Ordinary
Shares and the  transactions contemplated  thereby. Teva has  obtained from  the
Israeli  Securities Authority  an exemption  from the  requirement to  publish a
prospectus in connection  with the Merger.  Both the Listing  and the  Executive
Committees  of  the TASE  have recommended  to  the TASE  Board of  Directors to
consent in principle to list the Teva  Ordinary Shares to be issued pursuant  to
this  Proxy Statement/Prospectus.  The TASE Board  of Directors  is scheduled to
consider the matter on May 2, 1996.
 
RESALE OF TEVA ADSS
 
     All Teva ADSs received  by holders of Biocraft  Common Stock in the  Merger
will  have  been  registered  under  the  Securities  Act  and  will  be  freely
transferable, except that  Teva ADSs received  by persons who  are deemed to  be
affiliates of Biocraft (for purposes of Rule 145 under the Securities Act or for
purposes  of qualifying the Merger for pooling of interests accounting treatment
under Opinion 16 of the Accounting Principles Board and applicable SEC rules and
regulations) prior to  the Merger  may be resold  by them  only in  transactions
permitted  by the resale provisions of Rule 145 promulgated under the Securities
Act (or Rule 144 in the case of  such persons who become affiliates of Teva)  or
as  otherwise permitted by the  Securities Act. Persons who  may be deemed to be
affiliates of Biocraft or  Teva generally include  individuals or entities  that
control, are controlled by, or are under common control with, such party and may
include  certain  officers and  directors  of such  party  as well  as principal
shareholders of such party. The rights of affiliates of Biocraft to receive Teva
ADSs in the Merger are conditioned upon the execution by each of such affiliates
of a written agreement to the effect that such person will not offer or sell  or
otherwise dispose of any of the Teva ADSs or Teva Ordinary Shares represented by
such  ADSs  issued to  such  person in  the Merger  either  in violation  of the
Securities Act or  the rules and  regulations promulgated thereunder  or at  any
time  during the  period beginning  30 days  before the  Merger and  ending when
financial results covering  at least 30  days of post-merger  operations of  the
combined  entity have been  published. The ADRs  received in the  Merger by such
affiliates will  bear a  restrictive  legend to  such  effect. Pursuant  to  the
written  agreements described above,  Harold and Beatrice  Snyder and the trusts
which they have  established for  the benefit  of their  children have  received
certain registration rights from Teva.
 
RIGHT OF THE BIOCRAFT BOARD TO WITHDRAW RECOMMENDATION
 
     Under  the Merger  Agreement, the  Biocraft Board  may not  (i) withdraw or
modify, or propose to withdraw or modify, in a manner adverse to Teva or  Merger
Sub,  the Biocraft Board's approval or recommendation of the Merger Agreement or
the Merger, (ii) approve or recommend,  or propose to approve or recommend,  any
Takeover Proposal or (iii) enter into any agreement with respect to any Takeover
Proposal.  Notwithstanding  the  foregoing,  if the  Biocraft  Board  receives a
Takeover Proposal  that,  in  the  exercise of  its  fiduciary  obligations  (as
determined  in good faith by  the Biocraft Board, after  reviewing the advice of
outside counsel) it determines to be a Superior Proposal, the Biocraft Board may
withdraw or modify its approval or recommendation of the Merger Agreement or the
Merger, approve or recommend any Superior Proposal, enter into an agreement with
respect to such  Superior Proposal or  terminate the Merger  Agreement, in  each
case  at any  time after  the second  business day  following Teva's  receipt of
written notice advising  Teva that the  Biocraft Board has  received a  Superior
Proposal, specifying the material terms and conditions of such Superior Proposal
and  identifying  the  person making  such  Superior Proposal.  In  addition, if
Biocraft proposes  to enter  into  an agreement  with  respect to  any  Takeover
Proposal,  it shall  concurrently with entering  in into such  agreement pay, or
cause to be paid, to Teva the fees and expenses described below under 'TERMS  OF
THE MERGER AGREEMENT -- Certain Fees and Expenses'.
 
                                       36



<PAGE>
 
<PAGE>
                              DESCRIPTION OF TEVA
 
     Teva  develops, manufactures and markets  branded, generic (off-patent) and
branded generic pharmaceutical products.  As the largest branded  pharmaceutical
company  in Israel,  Teva has  successfully utilized  its integrated production,
manufacturing and research capabilities to establish a worldwide  pharmaceutical
business  focusing on the growing demand for generic drugs and the opportunities
for proprietary branded  products for  niche therapeutic  categories. Teva  also
manufactures   and  sells  bulk  pharmaceutical  chemicals,  hospital  supplies,
veterinary products, yeast and alcohol. Approximately 44% of its $667.7  million
sales  in 1995 were  in North America and  17% were in  Europe and other markets
outside of Israel.
 
     During 1995, Teva acquired two companies  in Europe. In October 1995,  Teva
acquired   Industrie  Chimiche   Italiane  S.p.A.   --  a   bulk  pharmaceutical
manufacturer located in  Milan, Italy. In  November 1995, Teva  acquired 78%  of
Biogal  Pharmaceutical  Works  Ltd.  ('Biogal')  --  a  Hungarian pharmaceutical
manufacturer as  well as  producer of  bulk pharmaceuticals.  Subsequently  Teva
acquired  additional shares of Biogal on the open market and currently holds 87%
of Biogal.
 
     Through  its  wholly  owned  U.S.  subsidiary,  Lemmon,  Teva  is  a  major
participant  in the U.S.  generic pharmaceutical market.  Lemmon's sales reached
$240.2 million in 1995,  and it currently markets  over 50 generic products.  In
1995,  Teva and  Lemmon received 12  generic drug approvals  and began marketing
eight of  such  products.  As  of  March 1,  1996,  Teva  had  17  generic  drug
applications  pending before  the FDA and  has product  development programs for
approximately 50 additional products.
 
     Teva possesses  a significant  bulk pharmaceutical  chemical  manufacturing
operation. As both a supplier and end user of pharmaceutical raw materials, Teva
believes  that  its experience  complying  with stringent  FDA  requirements and
proven manufacturing expertise are  significant competitive advantages  relative
to many of its smaller competitors.
 
     Teva  uses a combination of its  own research and development personnel and
its access to the  major research institutions in  Israel to develop  innovative
drug products for selected niche markets. To date these development efforts have
primarily  focused on products for neurological disorders, primarily Copaxone'r'
(COP-1), a  treatment for  multiple sclerosis.  During 1995,  the NDA  file  for
Copaxone'r' was submitted to the FDA, and similar applications were submitted to
the Medicines Control Agency in the United Kingdom and to the Ministry of Health
in Israel.
 
     Teva's  operations  are  conducted  directly  and  through  subsidiaries in
Israel, Europe  and  the United  States.  Teva  was incorporated  in  Israel  on
February  13, 1944 and is the successor to a number of Israeli corporations, the
oldest of which was established in 1901.  Teva grew through a series of  mergers
and  acquisitions  commencing  in  the  1960s  which  consolidated  part  of the
fragmented pharmaceutical  industry in  Israel, thereby  resulting in  increased
efficiency and greater production capacity.
 
     Teva's  executive offices  are located  at 5  Basel Street,  P.O. Box 3190,
Petach Tikva 49131  Israel, telephone number  011-972-3-9267267, telefax  number
011-972-3-9234050.
 
                            DESCRIPTION OF BIOCRAFT
 
     Biocraft  develops, manufactures and markets generic drugs. Its dosage form
product line  comprises  22  prescription drug  products  and  one  prescription
veterinary  product, constituting  an aggregate of  70 products  sold in various
oral dosage forms, including compressed tablets, two-piece hard-shell  capsules,
powders for oral solution or suspension and liquids. FDA approvals were required
and obtained for each of these products.
 
     More  than half of Biocraft's dosage form products have been semi-synthetic
penicillin or cephalosporin products. Biocraft  also manufactures and markets  a
range  of  other oral  dosage form  generic products,  including other  types of
antibiotics,   anti-infectives,   anti-depressants,   bronchial   dilators,    a
cardiovascular drug, a gastrointestinal drug, an analgesic and an anti-spasmodic
drug.
 
     Biocraft  also manufactures at  its Waldwick, New  Jersey facility the bulk
product it uses in  its semi-synthetic penicillin drugs  and produces bulk  form
Cephalexin  at  its  Mexico,  Missouri  facility.  Chemical  intermediates  also
manufactured in  Biocraft's Mexico,  Missouri facility  are used  in  Biocraft's
production  of certain antibiotics and are also  sold at times to third parties.
Biocraft is currently in the
 
                                       37
 
<PAGE>
 
<PAGE>
second year of a  three-year supply agreement with  Eli Lilly and Company  ('Eli
Lilly')  with respect  to one such  chemical intermediate.  Under the agreement,
Biocraft  supplies  Eli   Lilly  with  substantial   quantities  of  a   product
manufactured  at Biocraft's  Missouri facility  and Eli  Lilly supplies Biocraft
with substantial quantities of a raw material at a fixed exchange ratio.
 
     Biocraft's primary product  development strategies are  to manufacture  and
sell  in generic form  antibiotic drugs for which  Biocraft can maintain certain
cost  controls  by  manufacturing  the  chemical  intermediates  and/or   active
ingredients  in bulk.  Biocraft also  is developing  other types  of products in
order to broaden its product line. In so doing, it selects products for which it
expects initially  limited competition  as a  result of  approval  requirements,
complexity  of manufacture  or other  factors, and  products in  which the total
generic market is anticipated to be  large enough to allow for multiple  generic
versions.  Biocraft's research and development  generally consists of activities
related to new generic drug product development and research for developing  new
bulk manufacturing processes and products.
 
     Biocraft sells its products, primarily through its internal sales staff, to
approximately  300 customers. More than half  of Biocraft's gross sales of drugs
in dosage  form is  made under  its  own label  and the  balance is  made  under
customers'  labels; however, in all cases Biocraft  is named on the label as the
manufacturer. Sales of drugs in dosage forms are made primarily to distributors,
drug   wholesalers,   drugstore   chains,   mass   merchandisers,   other   drug
manufacturers,  health care institutions and  government agencies, almost all of
which are located in the United States.
 
                     COMPARATIVE STOCK PRICES AND DIVIDENDS
 
     The following table sets forth the high  and low sales prices per Teva  ADS
on the NASDAQ National Market and per share of Biocraft Common Stock on the NYSE
(on  a historical and equivalent per share  basis) on January 26, 1996, the last
trading day in the United States before the public announcement of the execution
of the Merger Agreement:
 
<TABLE>
<CAPTION>
                                                                     HIGH      LOW
                                                                    ------    ------
 
<S>                                                                 <C>       <C>
Teva ADSs........................................................   $46.00    $45.25
Biocraft Common Stock
     Historical..................................................   $13.63    $12.75
     Equivalent share basis(1)...................................    21.21     20.86
</TABLE>
 
- ------------
 
(1) Equivalent share basis is determined by multiplying the applicable Teva  ADS
    price by 0.461 to reflect the terms of the Merger Agreement.
 
     The  last reported sales price of the  Teva Ordinary Shares on the Tel Aviv
Stock Exchange on January 28, 1995, the last trading day on such exchange  prior
to  public announcement of the signing of  the Merger Agreement, was $4.58. Each
Teva ADS represents 10 Teva Ordinary Shares.
 
TEVA ADSS
 
     Teva ADSs  have  been traded  in  the United  States  since 1982  and  were
admitted to trading on the NASDAQ National Market in October 1987. Teva ADSs are
quoted under the symbol TEVIY. The Bank of New York serves as Depositary for the
ADSs. Each Teva ADS represents 10 Teva Ordinary
 
                                       38
 
<PAGE>
 
<PAGE>
Shares.  The table below sets  forth the high and  low last reported sale prices
for Teva ADSs during the indicated fiscal quarters.
<TABLE>
<CAPTION>
                                          HIGH            LOW                                                  HIGH       LOW
                                       ----------   -------------                                           ----------  -----
                                              (IN DOLLARS)                                                 (IN DOLLARS)
 
<S>                                      <C>            <C>            <C>                                      <C>       <C>
Year ended December 31, 1994:                                          Year ending December 31, 1996:
     First quarter....................   34 1/4         25             First quarter ........................   46 1/8   37 7/8
     Second quarter...................   27 3/8         22 1/2         Second quarter (through
     Third quarter....................   30 3/4         23 1/4         April 26, 1996 .......................   45 1/2   37 15/16
     Fourth quarter...................   29 1/4         22 7/8
 
Year ended December 31, 1995:
     First quarter....................   30 3/4         21 9/16
     Second quarter...................   38 3/8         29 3/8
     Third quarter....................   43             35 3/4
     Fourth quarter...................   47 1/8         34 7/8
 
</TABLE>
 
     On April 26, 1996, the  last reported sale price for  the Teva ADSs on  the
NASDAQ  National Market was $45.50. As of  April 25, 1996, there were 831 record
holders of Teva ADSs, which in total represented approximately 66% of the  total
outstanding  Teva Ordinary Shares,  and 819 of  such record holders  were in the
United States.
 
     On February  14, 1994,  the American  Stock Exchange,  the Chicago  Options
Exchange and the Pacific Stock Exchange began quoting options on Teva ADSs under
the symbol TEVIY.
 
     Since  May 1994, the Teva ADSs have  also been traded on SEAQ International
in London.
 
TEVA ORDINARY SHARES
 
     Teva Ordinary Shares have been listed on the Tel Aviv Stock Exchange  since
1951.  The table below sets forth the high  and low last reported sale prices of
the Teva Ordinary  Shares on the  Tel Aviv Stock  Exchange during the  indicated
fiscal quarters as reported by such exchange. The translation into United States
dollars  is based on the daily representative  rate of exchange published by the
Bank of Israel then in effect.
 
<TABLE>
<CAPTION>
                                          HIGH     LOW                                             HIGH     LOW
                                          -----   -----                                            -----   -----
                                          (IN DOLLARS)                                             (IN DOLLARS)
 
<S>                                       <C>     <C>    <C>                                       <C>     <C>
Year ended December 31, 1994:                            Year ending December 31, 1996:
     First quarter.....................    3.40    2.60  First quarter .........................    4.58    3.74
     Second quarter....................    2.75    2.19  Second quarter (through
     Third quarter.....................    2.98    2.22  April 28, 1996) .......................    4.48    3.70
     Fourth quarter....................    2.90    2.42
 
Year ended December 31, 1995:
     First quarter.....................    3.03    2.15
     Second quarter....................    3.73    2.92
     Third quarter.....................    4.25    3.67
     Fourth quarter....................    4.66    3.52
</TABLE>
 
     On April 28, 1996, the last reported sale price of Teva Ordinary Shares  on
the  Tel Aviv  Stock Exchange was  $4.48. As of  April 25, 1996,  there were 196
record holders of Teva Ordinary Shares.
 
DIVIDENDS ON TEVA ORDINARY SHARES
 
     For over 30 years  Teva has paid  dividends, and since  1987 Teva has  paid
dividends  on a regular quarterly basis. Future dividend policy will be reviewed
by the Board of Directors based upon conditions then existing, including  Teva's
earnings, financial condition, capital requirements and other factors. Dividends
are  declared  and  paid in  New  Israeli  Shekels ('NIS').  Such  dividends are
converted into dollars and paid by the Depositary of the ADSs for the benefit of
owners of ADSs.
 
                                       39
 
<PAGE>
 
<PAGE>
     Dividends paid  by  an Israeli  company  to shareholders  residing  outside
Israel  are currently subject to withholding of  Israeli income tax at a rate of
up to 25%. In the case of Teva, the applicable withholding tax rate will  depend
on  the particular  facilities which  have generated  the earnings  that are the
source of the dividend  and, accordingly, the applicable  rate will change  from
time to time. The rate of tax withheld on Teva's dividends has typically been at
25%.  United States  persons who  become owners  of Teva  ADSs must  include the
entire amount of any  dividend paid by  Teva with respect  to the Teva  Ordinary
Shares  (not reduced by any Israeli income taxes withheld) in their gross income
for U.S. Federal income  tax purposes. United  States corporations holding  Teva
ADSs  will not  be entitled  to the 70%  dividends received  deduction under the
Code. Residents of  the United  States generally  will have  withholding tax  in
Israel  deducted by  Teva. Such  persons may be  entitled to  relief from United
States taxation under the Code, using such tax either as a reduction of  taxable
income  or as  a dollar-for-dollar credit  against United States  tax subject to
certain limitations.
 
     The following table sets forth the amounts of the dividends paid in respect
of each period indicated prior to deductions for applicable Israeli  withholding
taxes:
 
<TABLE>
<CAPTION>
                  CENTS PER TEVA ADS                                       CENTS PER TEVA ADS
- ------------------------------------------------------   ------------------------------------------------------
 
<S>                                                <C>   <C>                                                <C>
Year ended December 31, 1991:                            Year ended December 31, 1994:
     1st interim................................   2.1   1st interim.....................................   6.6
     2nd interim................................   2.2   2nd interim.....................................   6.6
     3rd interim................................   2.2   3rd interim.....................................   6.6
     4th interim................................   2.5   4th interim.....................................   6.7
Year ended December 31, 1992:                            Year ended December 31, 1995:
     1st interim................................   2.5   1st interim.....................................   6.7
     2nd interim................................   2.5   2nd interim.....................................   6.6
     3rd interim................................   2.3   3rd interim.....................................   6.5
     4th interim................................   3.6   4th interim.....................................   6.4
Year ended December 31, 1993:                            Year ending December 31, 1996
     1st interim................................   3.7   1st interim.....................................   5.0
     2nd interim................................   5.2
     3rd interim................................   5.1
     4th interim................................   6.6
</TABLE>
 
BIOCRAFT COMMON STOCK
 
     Biocraft Common Stock is listed on the NYSE under the symbol BCL. The table
below  sets forth the high and low last reported sale prices for Biocraft Common
Stock on the NYSE during the indicated fiscal quarters.
<TABLE>
<CAPTION>
                                           HIGH        LOW                                                   HIGH        LOW
                                        ---------   ---------                                            ------------   -----
                                            (IN DOLLARS)                                                 (IN DOLLARS)
 
<S>                                       <C>          <C>           <C>                                       <C>       <C>
Year ended March 31, 1994:                                             Year ended March 31, 1996:
     First quarter.....................   26 1/2      15 3/4        First quarter..........................   22 1/2   17 5/8
     Second quarter....................   35          26 1/8        Second quarter.........................   21 1/4   16 7/8
     Third quarter.....................   37 5/8      18 7/8        Third quarter..........................   17 1/4   12 5/8
     Fourth quarter....................   21 3/4      14 3/4        Fourth quarter.........................   20 5/8   12 3/4
 
Year ended March 31, 1995:                                             Year ending March 31, 1997:
     First quarter.....................   18 1/8      13 5/8        First quarter (through
     Second quarter....................   17 1/8      11 3/4        April 26, 1996)........................   21       17 3/8
     Third quarter.....................   19 1/4      14 7/8
     Fourth quarter....................   19 1/4      15 1/4
 
</TABLE>
 
     On April 26, 1996, the last  reported sale price for Biocraft Common  Stock
on  the NYSE was $21.00. As  of April 22, 1996, there were 761 record holders of
Biocraft Common Stock.
 
                                       40
 
<PAGE>
 
<PAGE>
DIVIDENDS ON BIOCRAFT COMMON STOCK
 
     Biocraft has not paid  a cash dividend on  its Common Stock since  November
1994  and does not currently anticipate paying cash dividends in the foreseeable
future. On August 8, 1994, Biocraft declared  a cash dividend of $.10 per  share
on  its Common Stock,  which was paid on  November 22, 1994.  A cash dividend of
$.10 per share on Biocraft Common Stock had also been paid on November 18, 1993.
The payment of dividends is subject to the discretion of the Board of  Directors
of  Biocraft and is dependent upon  many factors, including Biocraft's earnings,
its capital needs and its  general financial condition. In addition,  Biocraft's
credit  agreement with General Electric Capital Corporation restricts Biocraft's
ability to pay  dividends unless  certain conditions  are satisfied  and in  any
event prohibits the payment of dividends in excess of $1.5 million per annum.
 
                                       41
 
<PAGE>
 
<PAGE>
          UNAUDITED PRO FORMA COMBINED CONDENSED FINANCIAL STATEMENTS
 
     The  following  unaudited pro  forma  combined condensed  balance  sheet at
December 31, 1995 gives effect to the Merger of Biocraft into Teva as if it  had
occurred  as of  December 31, 1995.  The following unaudited  pro forma combined
condensed statements of  operations for each  of the three  years in the  period
ended  December 31, 1995 gives effect to the acquisitions by Teva, in the fourth
quarter of  1995, of  Biogal Pharmaceutical  Works Ltd.  and Industrie  Chimiche
Italiane  S.p.A. (the 'Acquisitions') as if they had occurred on January 1, 1995
and to the  Merger as  if it  had occurred  on January  1, 1993.  The pro  forma
financial statements give effect to the above mentioned transactions as follows:
The  Merger is accounted for under the  'pooling of interests' method, while the
Acquisitions are accounted for under the 'purchase' method.
 
     Biocraft's  historical  financial   statements  and/or  summary   financial
information derived therefrom, presented herein or incorporated by reference are
presented  on the basis of fiscal years ending  on March 31. For purposes of the
pro forma  information,  Biocraft's statements  of  operations for  all  periods
presented  have been recast to  reflect the results of  operations on a calendar
year basis, prior to the combination of those statements with the statements  of
Teva.
 
     These unaudited pro forma statements have been prepared from, and should be
read  in conjunction with, the  historical consolidated financial statements and
the notes thereto of Teva and  Biocraft, which are incorporated by reference  in
this Proxy Statement/Prospectus.
 
     The  pro forma data  are presented for informational  purposes only and are
not necessarily indicative of the  operating results or financial position  that
would  have occurred had the Merger and the Acquisitions been consummated at the
dates indicated nor are they necessarily indicative of future operating  results
or financial position.
 
                                       42
 
<PAGE>
 
<PAGE>
              UNAUDITED PRO FORMA CONDENSED COMBINED BALANCE SHEET
                              AT DECEMBER 31, 1995
 
<TABLE>
<CAPTION>
                                                                                         PRO FORMA       PRO FORMA
                                                                TEVA      BIOCRAFT      ADJUSTMENTS      COMBINED
                                                               -------    --------      -----------      ---------
                                                                            (IN THOUSANDS US DOLLARS)
 
<S>                                                            <C>        <C>           <C>              <C>
                          ASSETS:
Current Assets:
     Cash and cash equivalents..............................    63,396       1,469                          64,865
     Short-term investments.................................    10,273                                      10,273
     Accounts receivable....................................   204,169      30,750                         234,919
     Inventories............................................   188,661      56,229         (9,184)(3a)     235,206
                                                                                             (500)(3b)
     Other current assets...................................                 3,686            (66)(3a)       3,620
                                                               -------    --------      -----------      ---------
          Total current assets..............................   466,499      92,134         (9,750)         548,883
Investments and non-current receivables.....................    47,890         180                          48,070
Property, plant and equipment
     Cost...................................................   423,549     137,148         (4,053)(3a)     556,644
     Less accumulated depreciation..........................   131,968      47,229           (571)(3a)     178,626
                                                               -------    --------      -----------      ---------
                                                               291,581      89,919         (3,482)         378,018
Intangibles and other assets................................    65,324       1,042           (700)(3c)      65,666
                                                               -------    --------      -----------      ---------
          Total assets......................................   871,294     183,275        (13,932)       1,040,637
                                                               -------    --------      -----------      ---------
                                                               -------    --------      -----------      ---------
                        LIABILITIES:
Current Liabilities:
     Short-term credit......................................   250,376       4,218                         254,594
     Current maturities of long-term debt...................                 4,848                           4,848
     Accounts payable and accrued expenses..................   151,331      27,923         12,800(3d)      192,054
                                                               -------    --------      -----------      ---------
          Total current liabilities.........................   401,707      36,989         12,800          451,496
Long-term debt..............................................    40,763      52,402                          93,165
Deferred taxes..............................................    11,052       4,133         (4,965)(3a)       7,320
                                                                                           (2,900)(3e)
Other liabilities...........................................    10,210                                      10,210
                                                               -------    --------      -----------      ---------
          Total liabilities.................................   463,732      93,524          4,935          562,191
Minority interest...........................................     4,679                                       4,679
Shareholders' equity:
     Share capital..........................................   122,173      43,680         (1,305)(3f)     164,548
     Other capital surplus..................................     9,129                                       9,129
     Retained earnings......................................   282,593      47,376         (7,767)(3a)     311,102
                                                                                          (11,100)(3e)
     Treasury stock.........................................   (11,012)     (1,305)         1,305(3f)      (11,012)
                                                               -------    --------      -----------      ---------
          Total shareholders' equity........................   402,883      89,751        (18,867)         473,767
                                                               -------    --------      -----------      ---------
Total liabilities and shareholders' equity..................   871,294     183,275        (13,932)       1,040,637
                                                               -------    --------      -----------      ---------
                                                               -------    --------      -----------      ---------
</TABLE>
 
                                       43
 
<PAGE>
 
<PAGE>
                     UNAUDITED PRO FORMA CONDENSED COMBINED
                            STATEMENT OF OPERATIONS
                      FOR THE YEAR ENDED DECEMBER 31, 1995
 
<TABLE>
<CAPTION>
                                                    1995        PRO FORMA    ADJUSTED               PRO FORMA          PRO FORMA
                                       TEVA     ACQUISITIONS   ADJUSTMENTS     TEVA     BIOCRAFT   ADJUSTMENTS         COMBINED
                                      -------   ------------   -----------   --------   --------   -----------         ---------
                                                            (IN THOUSANDS US DOLLARS EXCEPT PER ADS DATA)
 
<S>                                   <C>       <C>            <C>           <C>        <C>        <C>                 <C>
Sales...............................  667,677      83,174                    750,851     144,632      (1,029)(2e)       894,454
Costs of sales......................  389,519      63,884                    453,403     122,721       3,106(2a)        578,374
                                                                                                         173(2b)
                                                                                                      (1,029)(2e)
                                      -------   ------------                 --------   --------   -----------         ---------
    Gross profit....................  278,158      19,290                    297,448      21,911      (3,279)           316,080
Research and development expenses:
    Total expenses..................   67,934       4,324                     72,258      11,129         822(2c)         84,209
    Less grants and participations..  (36,345)                               (36,345 )                                  (36,345)
                                      -------   ------------                 --------   --------   -----------         ---------
                                       31,589       4,324                     35,913      11,129         822             47,864
Selling, general and                  131,411      10,167           236(2f)  141,814      14,035                        155,849
  administrative....................
Write-off in accordance with General
  Health Fund debt arrangement......    4,745                                  4,745                                      4,745
                                      -------   ------------      -----      --------   --------   -----------         ---------
Operating income....................  110,413       4,799          (236)     114,976      (3,253)     (4,101)           107,622
Financial expenses, net.............    8,475       3,834                     12,309       4,275                         16,584
Other income, net...................    4,766       2,970                      7,736         143                          7,879
                                      -------   ------------      -----      --------   --------   -----------         ---------
Income before income taxes..........  106,704       3,935          (236)     110,403      (7,385)     (4,101)            98,917
Income taxes........................   27,906       1,583                     29,489      (2,922)     (1,599)(2d)        24,968
                                      -------   ------------      -----      --------   --------   -----------         ---------
                                       78,798       2,352          (236)      80,914      (4,463)     (2,502)            73,949
Share in profits of associated
  companies.........................       27                                     27                                         27
Minority interest...................      967                                    967                                        967
                                      -------   ------------      -----      --------   --------   -----------         ---------
Net income before extraordinary        79,792       2,352          (236)      81,908      (4,463)     (2,502)            74,943
  item..............................
Extraordinary item..................                                                        (125)                          (125)
                                      -------   ------------      -----      --------   --------   -----------         ---------
Net income..........................   79,792       2,352          (236)      81,908      (4,588)     (2,502)            74,818
                                      -------   ------------      -----      --------   --------   -----------         ---------
                                      -------   ------------      -----      --------   --------   -----------         ---------
Earnings per ADS....................     1.46                                                                              1.22
Weighted average number of ADSs
  outstanding.......................   55,112                                                          6,566             61,678
</TABLE>
 
                                       44
 
<PAGE>
 
<PAGE>
                   UNAUDITED PRO FORMA CONSOLIDATED COMBINED
                            STATEMENT OF OPERATIONS
                      FOR THE YEAR ENDED DECEMBER 31, 1994
 
<TABLE>
<CAPTION>
                                                                                      PRO FORMA         PRO FORMA
                                                               TEVA      BIOCRAFT    ADJUSTMENTS        COMBINED
                                                              -------    --------    -----------        ---------
                                                                 (IN THOUSANDS US DOLLARS EXCEPT PER ADS DATA)
 
<S>                                                           <C>        <C>         <C>                <C>
Sales......................................................   587,711     137,377         (231)(2e)      724,857
Cost of sales..............................................   329,238     112,163        1,809(2a)       443,009
                                                                                            30(2b)
                                                                                          (231)(2e)
                                                              -------    --------    -----------        ---------
Gross profit...............................................   258,473      25,214       (1,839)          281,848
Research and development expenses:
     Total expenses........................................    50,814      11,300          400(2c)        62,514
     Less grants and participations........................   (14,264)                                   (14,264)
                                                              -------    --------    -----------        ---------
                                                               36,550      11,300          400            48,250
 
Selling, general and administrative........................   115,193      14,450                        129,643
                                                              -------    --------    -----------        ---------
Operating income...........................................   106,730        (536)      (2,239)          103,955
Financial expenses, net....................................    10,994       3,715                         14,709
Other income, net..........................................     2,251         155                          2,406
                                                              -------    --------    -----------        ---------
Income before income taxes.................................    97,987      (4,096)      (2,239)           91,652
Income taxes...............................................    27,022      (2,270)        (873)(2d)       23,879
                                                              -------    --------    -----------        ---------
                                                               70,965      (1,826)      (1,366)           67,773
Share in profits of associated companies...................       685                                        685
Minority interest..........................................        (4)                                        (4)
                                                              -------    --------    -----------        ---------
Net income.................................................    71,646      (1,826)      (1,366)           68,454
                                                              -------    --------    -----------        ---------
                                                              -------    --------    -----------        ---------
Earnings per ADS...........................................      1.32                                       1.12
Weighted average number of ADSs outstanding................    54,968                    6,566            61,534
</TABLE>
 
                                       45
 
<PAGE>
 
<PAGE>
                     UNAUDITED PRO FORMA CONDENSED COMBINED
                            STATEMENTS OF OPERATIONS
                      FOR THE YEAR ENDED DECEMBER 31, 1993
 
<TABLE>
<CAPTION>
                                                                                      PRO FORMA         PRO FORMA
                                                               TEVA      BIOCRAFT    ADJUSTMENTS        COMBINED
                                                              -------    --------    -----------        ---------
                                                                 (IN THOUSANDS US DOLLARS EXCEPT PER ADS DATA)
 
<S>                                                           <C>        <C>         <C>                <C>
Sales......................................................   501,975     147,534        (782)(2e)       648,727
Cost of sales..............................................   288,120     108,850          38(2a)        396,216
                                                                                          (10)(2b)
                                                                                         (782)(2e)
                                                              -------    --------    -----------        ---------
Gross profit...............................................   213,855      38,684         (28)           252,511
Research and development expenses:
     Total expenses........................................    31,289      10,140          61(2c)         41,490
     Less grants and participations........................    (6,604)                                    (6,604)
                                                              -------    --------    -----------        ---------
                                                               24,685      10,140          61             34,886
 
Selling, general and administrative........................   101,189      11,949                        113,138
                                                              -------    --------    -----------        ---------
Operating income...........................................    87,981      16,595         (89)           104,487
Financial expenses, net....................................     5,255       4,109                          9,364
Other income, net..........................................     2,475       1,691                          4,166
                                                              -------    --------    -----------        ---------
Income before income taxes.................................    85,201      14,177         (89)            99,289
Income taxes...............................................    27,526       5,032         (35)(2d)        32,523
                                                              -------    --------    -----------        ---------
                                                               57,675       9,145         (54)            66,766
Share in profits of associated companies...................         0                                          0
Minority interest..........................................      (200)          0                           (200)
                                                              -------    --------    -----------        ---------
Net income before cumulative effect of an accounting
  change...................................................    57,475       9,145         (54)            66,566
Cumulative effect of an accounting change..................                    30                             30
                                                              -------    --------    -----------        ---------
Net income.................................................    57,475       9,175         (54)            66,596
                                                              -------    --------    -----------        ---------
                                                              -------    --------    -----------        ---------
Earnings per ADS...........................................      1.07                                       1.10
Weighted average number of ADSs outstanding................    54,950                   6,566             61,516
</TABLE>
 
                                       46
 
<PAGE>
 
<PAGE>
                NOTES TO UNAUDITED PRO FORMA COMBINED CONDENSED
                              FINANCIAL STATEMENTS
 
1. The  unaudited pro forma combined  condensed financial statements reflect the
   issuance of approximately 6.6  million Teva ADSs in  exchange for all of  the
   shares  of Biocraft  Common Stock. This  reflects an Exchange  Ratio of 0.461
   Teva ADS for each outstanding share of Biocraft Common Stock which represents
   an indicated value of $20.86 per share of Biocraft Common Stock based on  the
   closing price of $45 1/4 of Teva ADSs at January 26, 1996.
 
2. Pro forma adjustments relating to the pro forma statements of operations:
 
        (a)      an  adjustment to Biocraft's cost of sales to conform to Teva's
                 inventory valuation policies (principally an adjustment for the
                 change from 'Last-in-First-Out' to 'First-in-First-Out');
 
        (b)      an adjustment  to   Biocraft's  cost  of    sales  to   conform
                 Biocraft's  policy   of    capitalizing   certain    costs   in
                 construction   projects,   primarily   internal labor, benefits
                 and overhead to Teva's  policy of  expensing similar costs;
 
        (c)      an  adjustment to Biocraft's  research and development expenses
                 to conform  to  Teva's  policy of  valuing  raw  materials  for
                 products   prior  to  regulatory  approval  at  their  expected
                 replacement costs  versus  Biocraft's policy  of  valuing  such
                 inventory  at the  lower of  cost or  market and  to conform to
                 Teva's  policy  of  not  capitalizing  certain  materials   and
                 supplies used in production prior to regulatory approval;
 
        (d)      the  above conforming adjustments have been tax effected at the
                 overall expected rate;
 
        (e)      inter-company sales have been eliminated;
 
        (f)      an adjustment  to  the 1995  statements  of operations  of  the
                 Acquisitions  to reflect the amortization of the goodwill which
                 arose in these acquisitions in the period in 1995 prior to  the
                 acquisition   by  Teva;   the  statements  of   income  of  the
                 Acquisitions do  not  reflect non-recurring  charges  resulting
                 from their acquisition by Teva.
 
3. Pro forma adjustments relating to the pro forma balance sheet:
 
        (a)      inventories,   property  plant  and  equipment,  other  assets,
                 deferred taxes and retained earnings were adjusted as a  result
                 of the conforming adjustments described in adjustments 2a, b, c
                 and d;
 
        (b)      inventories   have  been  adjusted to  reflect  Teva's expected
                 discontinuance of  certain  product presentations and packaging
                 lines after the completion of the Merger;
 
        (c)      other  assets have been adjusted  to write-off certain deferred
                 costs, principally loan  origination costs,  to reflect  Teva's
                 expected  repayment  of  such  loans  after  completion  of the
                 Merger;
 
        (d)      other accrued  expenses  have  been  adjusted  to  reflect  (i)
                 estimated professional fees and other expenses directly related
                 to  the  Merger,  (ii)  Teva's  planned  approach  for handling
                 litigation claims after the completion of the Merger and  (iii)
                 severance  costs related to the anticipated restructuring costs
                 resulting from the elimination  of certain redundant  personnel
                 after the completion of the Merger;
 
        (e)      to  reflect in retained earnings and deferred taxes adjustments
                 3b, c and d;
 
        (f)      Biocraft treasury stock has been eliminated.
 
                                       47


<PAGE>
 
<PAGE>
                         TERMS OF THE MERGER AGREEMENT
 
     The  following description of certain provisions of the Merger Agreement is
only a summary and does not purport to be complete. This discussion is qualified
in its entirety by reference to the complete text of the Merger Agreement, which
is attached to this  Proxy Statement/Prospectus as Annex  I and incorporated  by
reference herein.
 
THE MERGER; EXCHANGE AND CONVERSION OF SHARES
 
     Pursuant  to  and  subject  to  the  terms  and  conditions  of  the Merger
Agreement, at  the  Effective Time  Merger  Sub will  be  merged with  and  into
Biocraft.  Biocraft  will  be  the  surviving  corporation  in  the  Merger (the
'Surviving Corporation'). All shares of Biocraft Common Stock, other than shares
owned by  Biocraft as  treasury stock,  shall  be converted  into and  shall  be
canceled  in exchange for  the right to  receive 0.461 Teva  ADSs, each Teva ADS
representing 10 Teva Ordinary  Shares, duly issued and  credited as fully  paid.
All  such shares  of Biocraft  Common Stock shall  no longer  be outstanding and
shall automatically be canceled and retired  and shall cease to exist, and  each
holder  of a certificate  representing any such  shares shall cease  to have any
rights with respect thereto,  except the right  to receive the  Teva ADSs to  be
issued  in exchange  therefor upon  the surrender  of such  certificate, without
interest. All  shares of  Biocraft Common  Stock which  are held  in  Biocraft's
treasury  shall be canceled and retired prior to the Effective Time and no share
capital or  other consideration  shall  be delivered  in exchange  therefor.  In
consideration  of the issue  to Teva by  the Surviving Corporation  of shares of
common stock  of the  Surviving  Corporation and  the cancellation  of  Biocraft
Shares,  Teva will allot, in exchange for the  issue to Teva of all the unissued
shares of common stock of the Surviving Corporation, the Teva Ordinary Shares to
be issued to  the Exchange Agent  on behalf  of such persons  as Biocraft  shall
nominate  for  the  purpose of  giving  effect  to the  conversion  and exchange
referred to above.
 
     Based on the number  of shares of Biocraft  Common Stock outstanding as  of
April 22, 1996, assuming that all Biocraft stock options are exercised, the Teva
ADSs  to be issued in the Merger will represent 66,163,610 Teva Ordinary Shares,
or  approximately  10.7%   of  the   outstanding  Teva   Ordinary  Shares.   See
' -- Treatment of Biocraft Stock Options'.
 
     No  fraction of a Teva ADS will be issued in connection with the Merger. If
a holder of shares of Biocraft Common  Stock would otherwise be entitled at  the
Effective Time to a fraction of a Teva ADS, such stockholder will be entitled to
receive  from the Exchange  Agent an amount  in cash in  lieu of such fractional
Teva ADS, representing such holder's proportionate interest in the net  proceeds
from the sale on the NASDAQ National Market of the aggregate of the fractions of
ADSs  which would otherwise have been issued  by the Exchange Agent on behalf of
all such holders.
 
EXCHANGE OF SHARE CERTIFICATES
 
     At the Effective Time, certificates representing shares of Biocraft  Common
Stock  ('Biocraft Certificates') will be deemed to represent solely the right to
receive the number of Teva Ordinary  Shares represented by Teva ADSs  determined
as described above.
 
     As  soon  as practicable  after  the Effective  Time,  Teva will  cause the
Exchange Agent to mail or make available  a notice and letter of transmittal  to
each  holder of record of shares of Biocraft Common Stock at the Effective Time,
advising such holder of the effectiveness  of the Merger and the procedures  for
surrendering  to the Exchange  Agent any Biocraft  Certificates for exchange. If
any Teva ADSs are to be issued to  a person other than the person in whose  name
the Biocraft Certificate is registered, it shall be a condition to such issuance
that  the Biocraft  Certificate shall  be properly  endorsed or  otherwise be in
proper form for transfer and that  the person requesting such issuance must  pay
to  the Exchange Agent any transfer or other  taxes required as a result of such
issuance to a person other than the  registered holder or must establish to  the
satisfaction  of the Exchange Agent that such tax either has been paid or is not
payable.
 
     Each holder of shares of Biocraft Common Stock so converted, upon surrender
to the Exchange  Agent of  one or  more Biocraft  Certificates for  cancellation
together  with a properly  completed letter of transmittal,  will be entitled to
receive ADRs representing 0.461 Teva ADSs  in respect of each share of  Biocraft
Common  Stock  and  cash  in lieu  of  any  fractional Teva  ADSs  in  an amount
calculated as
 
                                       48
 
<PAGE>
 
<PAGE>
described above. The Exchange Agent will not issue ADRs in respect to shares  of
Biocraft  Common Stock which have not been  surrendered within six months of the
Effective Time. Thereafter, holders of shares of Biocraft Common Stock may  look
only  to Teva and the  Surviving Corporation for issuance  of ADRs in respect of
such shares.  Notwithstanding  the foregoing,  neither  Teva nor  the  Surviving
Corporation shall be liable to any holder of shares of Biocraft Common Stock for
any  securities delivered or  any amount paid  to a public  official pursuant to
applicable abandoned property laws. Any Teva ADSs remaining unclaimed by holders
of shares of Biocraft Common Stock three years after the Effective Time (or such
earlier date immediately prior to such  time as such securities would  otherwise
escheat  to or  become property  of any governmental  entity or  as is otherwise
provided by applicable law) shall, to the extent permitted by applicable law, be
free and  clear of  any claims  or interest  of any  person previously  entitled
thereto.
 
     No dividends, interest or other distributions with respect to securities of
Teva  or the Surviving  Corporation issuable with respect  to shares of Biocraft
Common Stock  shall  be  paid  to  the  holder  of  any  unsurrendered  Biocraft
Certificates  until  such  Biocraft  Certificates  are  surrendered.  Upon  such
surrender, there shall be  paid, without interest, to  the person in whose  name
the  Teva ADSs are registered, all  dividends and other distributions payable in
respect of such securities on a date  subsequent to, and in respect of a  record
date after, the Effective Time.
 
TREATMENT OF BIOCRAFT STOCK OPTIONS
 
     Prior  to the Effective  Time, the Biocraft Board  will take all reasonably
necessary action to (i) terminate the Biocraft Incentive Stock Option Plan  (and
all options thereunder), the Biocraft 1987 Directors' Stock Option Plan (and all
options thereunder) and all other Biocraft plans or agreements providing for the
grant  of stock options, (ii) notify the  holder of options terminated under (i)
above, and (iii)  offer the  holder of  each such  option the  right by  written
notice  to exercise, by  written notice, all  such options, whether  or not then
exercisable by the terms of the applicable option agreement. Options as to which
no notice of exercise is received by  Biocraft will be converted into the  right
to  receive promptly  after the  Effective Time,  as to  each share  of Biocraft
Common Stock covered thereby (without regard to any then applicable restrictions
on the exercise  of such options),  the number  of Teva ADSs  determined by  (a)
multiplying  the  Exchange Ratio  by  the fair  market value  of  an ADS  on the
Effective Date, (b) subtracting from the product of such multiplication the  sum
of the applicable per share exercise price plus applicable per share withholding
for  taxes (which will be appropriately remitted to the applicable tax authority
on behalf of such optionee) and (c)  dividing the amount obtained in clause  (b)
by  the fair market value of a Teva ADS on the Effective Date. For such purpose,
the fair market value of a Teva ADS on the NASDAQ National Market shall mean the
average of the last sale prices of a  Teva ADS on the NASDAQ National Market  on
each  of the  ten trading days  ending two  trading days prior  to the Effective
Date. In addition, prior to the Effective  Time, but subject to the Merger,  the
Biocraft  Board  will  cause Biocraft's  Restricted  Stock Purchase  Plan  to be
amended to (i) provide that no further restricted stock grants be made after the
Effective Time and (ii) provide that the terms and conditions of such Plan  will
apply  to the Teva ADSs  and Teva Ordinary Shares issued  upon the Merger to the
holders of restricted stock under such  Plan, and such holders shall  thereafter
hold such Teva ADSs and Teva Ordinary Shares subject to the terms and conditions
of  such Plan, including without limitation any requirement for the legending of
certificates evidencing such securities.
 
EFFECTIVE TIME
 
     The Effective Time of the Merger, at  which time the closing of the  Merger
will occur and the conversion of the shares of Biocraft Common Stock will become
effective,  will be the time  of the filing of a  Certificate of Merger with the
Secretary of State of the State of Delaware or at such later time as is provided
in the Certificate  of Merger.  This filing will  occur as  soon as  practicable
following  the approval of the Merger  Agreement by the stockholders of Biocraft
and the satisfaction or  waiver of other conditions  precedent set forth in  the
Merger  Agreement, but in no  event later than the  fifth business day after the
satisfaction or waiver of all conditions or at such other time and place and  on
such  other date  as Teva  and Biocraft  mutually agree.  The Effective  Time is
currently expected to take place on or about May 31, 1996. See ' --  Termination
Rights' and ' -- Conditions to the Merger'.
 
                                       49
 
<PAGE>
 
<PAGE>
TERMINATION RIGHTS
 
     The  Merger Agreement may be terminated and  the Merger may be abandoned at
any time prior to the  Effective Time (whether before  or after approval of  the
Merger  by the stockholders of  Biocraft) by mutual consent  of Biocraft, on the
one hand, and of Teva and  Merger Sub, on the other  hand, or by either Teva  or
Biocraft, if:
 
          (i) the Effective Time shall not have occurred by August 31, 1996;
 
          (ii)  there shall be any law  or regulation of any competent authority
     that makes consummation of the Merger illegal or otherwise prohibited or if
     any judgment,  injunction,  order  or decree  of  any  competent  authority
     prohibiting  such  transaction is  entered  and such  judgment, injunction,
     order or decree shall have become final and nonappealable; or
 
          (iii) there has been a material breach of any covenant or a breach  of
     any  representation or warranty in the Merger  Agreement on the part of the
     other, which breach of representation or warranty individually or, together
     with all other such breaches, materially and adversely affects the value of
     the breaching  party,  provided that  any  such  breach of  a  covenant  or
     representation  or  warranty has  not been  cured  within 15  business days
     following receipt by the breaching party of notice of such breach.
 
     The Merger Agreement may be terminated  by Biocraft if Biocraft receives  a
Takeover  Proposal and  its Board of  Directors reasonably  determines that such
Takeover Proposal (as defined below in  'No Solicitation of Other Offers') is  a
Superior  Proposal (as defined below in 'No Solicitation of Other Offers') after
the second business  day following receipt  by Teva of  notice of such  Superior
Proposal  specifying the material terms and  conditions of the Superior Proposal
and  identifying  the  person  making  such  Superior  Proposal;  provided  that
termination  under this clause is not  effective until Biocraft has made payment
in full of the Termination  Fee (as defined below  in 'No Solicitation of  Other
Offers').
 
     The Merger Agreement may be terminated by Teva if:
 
          (a)  the  required  approval  of the  Merger  by  the  stockholders of
     Biocraft shall not have  been obtained by reason  of the failure to  obtain
     the  required vote  at a duly  held meeting  of the stockholders  or at any
     adjournment thereof;
 
          (b) the Special Meeting is canceled or is otherwise not held prior  to
     August  15, 1996 (except  as a result  of a judgment,  injunction, order or
     decree of any  competent authority  or events or  circumstances beyond  the
     reasonable control of Biocraft); or
 
          (c)  the Biocraft Board of Directors  shall have withdrawn or modified
     in a manner  adverse to  Teva its  approval or  recommendation to  Biocraft
     stockholders  of the Merger Agreement or  the Merger or shall have approved
     or recommended to Biocraft stockholders that  they accept the terms of  any
     Takeover  Proposal  or shall  have resolved  to take  any of  the foregoing
     actions or  a  Third  Party  Acquisition  shall  have  occurred;  provided,
     however, that Biocraft is obligated to pay the termination fee described in
     '  -- Certain Fees  and Expenses'. 'Third Party  Acquisition' is defined in
     the Merger Agreement as the occurrence of any of the following events:  (x)
     the  acquisition of  Biocraft by merger,  tender offer or  otherwise by any
     person other  than Teva,  Merger Sub  or any  affiliate thereof  (a  'Third
     Party');  (y) the acquisition by a Third Party  of 20% or more of the total
     assets of  Biocraft and  its subsidiaries,  taken as  a whole;  or (z)  the
     acquisition  by a Third  Party of 20%  or more of  the outstanding Biocraft
     Common Stock.
 
     Upon termination,  the  Merger Agreement  shall  become void  and  have  no
effect,  and there shall be no liability  thereunder on the part of Teva, Merger
Sub or Biocraft, except for liability for breach and except that the  provisions
governing  confidentiality and costs and  expenses shall survive any termination
of the Merger Agreement.
 
CERTAIN FEES AND EXPENSES
 
     Except as provided below, all fees and expenses incurred in connection with
the Merger,  the  Merger Agreement  and  the consummation  of  the  transactions
contemplated  thereby  shall  be paid  by  the  party incurring  such  costs and
expenses, whether or not the Merger is consummated.
 
                                       50
 
<PAGE>
 
<PAGE>
     If the  Merger  Agreement  is  terminated  due  to  a  material  breach  of
covenants,  representations or warranties, then the breaching party must pay all
actual out-of-pocket costs and expenses  of the non-breaching party incurred  in
connection  with the Merger Agreement and the transactions contemplated thereby,
including, without limitation, legal, professional and service fees and expenses
(the  'Expenses').  If  the  Merger  Agreement  is  terminated  by  Biocraft  in
accordance  with  the provisions  described under  'THE MERGER  -- Right  of the
Biocraft Board to Withdraw Recommendation' or is terminated by Teva as a  result
of  (i) the failure of  Biocraft to obtain the  required vote of stockholders or
hold the Special Meeting by August 15,  1996 (except as a result of a  judgment,
injunction,   order  or  decree   of  any  competent   authority  or  events  or
circumstances beyond the reasonable control of Biocraft), (ii) the withdrawal or
modification by the Biocraft  Board of its recommendation  of the Merger or  the
recommendation  of a  Takeover Proposal,  or the  adoption of  a resolution with
respect thereto, or  (iii) the  occurrence of  a Third  Party Acquisition,  then
Biocraft must pay the Expenses of Teva and Merger Sub.
 
     The   Merger  Agreement  requires  Biocraft  to  pay  promptly  to  Teva  a
termination fee  in  the  amount  of  $6 million  if  the  Merger  Agreement  is
terminated  by Biocraft in  accordance with the  provisions described under 'THE
MERGER   --  Right of  the  Biocraft Board  to  Withdraw Recommendation'  or  is
terminated  by Teva  as a result  of (i)  the withdrawal or  modification by the
Biocraft Board of  its approval or  recommendation of the  Merger to  Biocraft's
stockholders or its approval or recommendation to Biocraft's stockholders of any
Takeover Proposal, or its resolution to do the foregoing, (ii) the occurrence of
a  Third  Party  Acquisition,  or  (iii)  a  material  breach  of  any covenant,
representation or warranty of  Biocraft in the Merger  Agreement or the  Special
Meeting  being canceled or not being held by August 15, 1996 (except as a result
of a judgment, injunction, order or decree of any competent authority or  events
beyond  the  reasonable  control of  Biocraft)  and,  within 12  months  of such
termination, a transaction constituting a Third Party Acquisition is consummated
involving any person with whom Biocraft  or its agents had any discussions  with
respect  to a Third Party Acquisition, to  whom Biocraft or its agents furnished
information with respect to or with a  view to a Third Party Acquisition or  who
had  submitted  a Takeover  Proposal or  expressed any  interest publicly  or to
Biocraft in a Third Party Acquisition,  in each case prior to such  termination.
The  Merger  Agreement  also  requires  Teva  to  promptly  pay  to  Biocraft  a
termination fee  in  the  amount  of  $6 million  if  the  Merger  Agreement  is
terminated due to a material breach of a covenant, representation or warranty of
Teva  in the Merger Agreement and, within 12 months after such termination, Teva
is acquired by merger, tender  offer or otherwise, or  a person acquires 20%  or
more  of Teva's total assets or outstanding  Ordinary Shares or Teva enters into
an agreement with respect to the foregoing.
 
CONDITIONS TO THE MERGER
 
     The  parties'  obligations  to  effect  the  Merger  are  subject  to   the
satisfaction  or waiver at or prior to the Effective Time of various conditions,
including: (i) approval of the Merger Agreement by the requisite holders of  the
Biocraft   Common  Stock  in  accordance  with  applicable  law  and  Biocraft's
Certificate of  Incorporation and  By-laws;  (ii) any  waiting period  (and  any
extension  thereof) under the HSR Act applicable to the Merger having expired or
been terminated; (iii)  no preliminary  or permanent injunction  or other  order
having  been issued by  any court or  by any governmental  or regulatory agency,
body or authority which enjoins, restrains or prohibits the consummation of  the
Merger  or has the effect of making the Merger illegal and which is in effect at
the Effective Time (each party  has agreed to use its  best efforts to have  any
such  injunction  or  order lifted);  (iv)  the  absence of  any  statute, rule,
regulation, executive order,  decree or order  of any kind  which prohibits  the
consummation  of the Merger or has the  effect of making the Merger illegal; (v)
consent in principle having been granted by  the TASE to list the Teva  Ordinary
Shares  to  be issued  in connection  with  the Merger;  (vi) the  admission for
trading of the Teva ADSs on the  NASDAQ National Market upon official notice  of
issuance;  (vii) the effectiveness of the Registration Statement and the absence
of any stop order or  proceeding for a stop  order; (viii) Teva having  received
the  required  permit  from  the  Israeli  Securities  Authority  to  publish  a
prospectus in connection with  the Merger or having  obtained an exemption  from
such requirement; (ix) consent of the Controller of Foreign Currency of the Bank
of  Israel having been obtained to the Merger, the issuance of the Teva Ordinary
Shares in connection therewith  and the other  transactions contemplated by  the
Merger Agreement; (x) consents having been
 
                                       51
 
<PAGE>
 
<PAGE>
obtained  from  government  bodies  and  authorities,  including  the  Insurance
Commissioner of the State  of Hawaii which are  required in order to  consummate
the  Merger and the other transactions  contemplated by the Merger Agreement and
the failure  to  obtain  which would  have  a  material adverse  effect  on  the
condition (financial or otherwise) of Teva and its subsidiaries taken as a whole
after  giving effect to the Merger; (xi)  Biocraft having received an opinion in
form and substance  satisfactory to it  from Proskauer Rose  Goetz &  Mendelsohn
LLP, counsel to Biocraft, and Teva having received the opinion of Willkie Farr &
Gallagher,  counsel to Teva, to  the effect that the  Merger will be treated for
United States Federal income tax purposes as a reorganization within the meaning
of Section 368(a) of the Code and  that Biocraft, Teva and Merger Sub will  each
be  a party to that  reorganization within the meaning  of Section 368(b) of the
Code; (xii) no general suspension or  limitation of trading having been  imposed
on  the Teva  Ordinary Shares  or Teva  ADSs or  on securities  generally on the
NASDAQ National Market; and (xiii)  the execution of employment agreements  with
Biocraft by Harold Snyder and Beatrice Snyder.
 
     Further  conditions precedent to the obligations  of Teva and Merger Sub to
effect the  Merger  are:  (i) the  accuracy  in  all material  respects  of  the
representations  and warranties of  Biocraft in the  Merger Agreement unless the
failure  of  such  representations  and  warranties  to  be  accurate  does  not
materially and adversely affect the value of Biocraft and its subsidiaries taken
as  a whole; (ii) the  performance in all material  respects of all obligations,
agreements, covenants  and  conditions  of  Biocraft  contained  in  the  Merger
Agreement  to be performed or complied with prior to the Closing Date; (iii) all
persons who are  'affiliates' of  Biocraft for purposes  of Rule  145 under  the
Securities  Act  having  delivered a  written  agreement in  form  and substance
satisfactory to Teva with respect to Rule  145 of the Securities Act; (iv)  Teva
having  received an opinion of Proskauer Rose Goetz & Mendelsohn LLP, counsel to
Biocraft, in the form annexed to the Merger Agreement; (v) Teva having  received
a  comfort letter from Ernst  & Young LLP, independent  auditors to Biocraft, in
form and substance satisfactory  to Teva; (vi) Teva  having received an  opinion
from  Kesselman & Kesselman, independent auditors to Teva, stating that there is
no fact or circumstance concerning Teva or Merger Sub known to them which  would
cause  the Merger  not to be  recorded for  accounting purposes as  a pooling of
interests under both Israel GAAP and US GAAP; (vii) Biocraft having received for
each real property  owned or  operated by Biocraft  or any  of its  subsidiaries
located  in  the State  of  New Jersey,  either  a Letter  of Non-Applicability,
approval by the  New Jersey  Department of Environmental  Protection and  Energy
('DEP')  of a  Negative Declaration submitted  by Biocraft, a  no further action
letter from  DEP, the  filing by  Biocraft of  a De  Minimis Quantity  Exemption
Affidavit,  a letter of authorization for the  transfer of ownership from DEP or
approval by  DEP  of  a  Remediation Agreement  (any  of  the  foregoing,  'ISRA
Clearance')  pursuant to the  New Jersey Industrial  Site Recovery Act, N.J.S.A.
13:1K-6 et seq. and the regulations of DEP promulgated thereunder (collectively,
'ISRA'); and (viii) Teva having received  any necessary permit from the  Israeli
Securities Authority or an exemption from such requirement.
 
     Further  conditions precedent to the obligations  of Biocraft to effect the
Merger are: (i) the accuracy in all material respects of the representations and
warranties of Teva and Merger Sub in the Merger Agreement unless the failure  of
such  representations  and warranties  to be  accurate  does not  materially and
adversely affect the value of Teva and  its subsidiaries taken as a whole;  (ii)
the  performance  in  all  material  respects  of  all  obligations, agreements,
covenants and  conditions  of  Teva  and Merger  Sub  contained  in  the  Merger
Agreement  to be  performed or  complied with prior  to the  Closing Date; (iii)
Biocraft having received  opinions of  Willkie Farr &  Gallagher, United  States
counsel  to Teva, and  S. Horowitz & Co.,  Israeli counsel to  Teva, in the form
annexed to the Merger Agreement; (iv) Biocraft having received a comfort  letter
from  Kesselman & Kesselman, independent auditors to Teva, in form and substance
satisfactory to Biocraft;  (v) Biocraft having  received an opinion  of Ernst  &
Young  LLP, independent auditors of  Biocraft, stating that there  is no fact or
circumstance concerning Biocraft or its  subsidiaries known to them which  would
cause  the Merger  not to be  recorded for  accounting purposes as  a pooling of
interests under US GAAP; (vii) Teva  having executed the agreements referred  to
above  with  the  affiliates  of  Biocraft;  and  (viii)  Teva  having delivered
undertakings from each of its officers  and directors to refrain from  effecting
sales  of  Teva Ordinary  Shares or  Teva  ADSs until  after the  publication of
financial statements reflecting the combined  operating results of Biocraft  and
Teva for a period of not less than 30 days after the Effective Time.
 
                                       52
 
<PAGE>
 
<PAGE>
     The  foregoing  conditions  may  be  waived,  to  the  extent  permitted by
applicable law, by the party or parties affected by such waiver.
 
REPRESENTATIONS AND WARRANTIES
 
     The  Merger  Agreement  contains  various  customary  representations   and
warranties  relating to, among  other things, (i) each  of Biocraft's and Teva's
organization,  capital  structure  and  similar  corporate  matters,  (ii)   the
financial  statements of each  of Biocraft and Teva,  (iii) the authorization of
the Merger Agreement by each of Biocraft and Teva and related matters, (iv)  the
absence of any conflicts under charters or by-laws, receipt of required consents
or approvals, and absence of violations of any instruments or law, (v) documents
filed  by  Biocraft  and Teva  with  the  SEC and  the  accuracy  of information
contained therein,  (vi)  the  absence  of a  material  adverse  change  in  the
business,  properties, assets, liabilities, operations, results of operations or
condition (financial or otherwise) of Biocraft  and its subsidiaries taken as  a
whole  and  Teva and  its  subsidiaries taken  as  a whole,  each  since certain
specified dates, (vii) in  the case of Biocraft,  retirement and other  employee
plans  and  matters,  (viii)  certain FDA  matters,  (ix)  certain environmental
matters, (x)  litigation,  (xi)  compliance  with law,  (xii)  in  the  case  of
Biocraft,  the stockholder vote  required and (xiii)  broker's or finder's fees.
The representations and  warranties in  the Merger Agreement  (other than  those
relating to broker's or finder's fees) will not survive the Effective Time.
 
INDEMNIFICATION; OFFICERS' AND DIRECTORS' LIABILITY INSURANCE
 
     Biocraft,  the surviving  corporation in  the Merger,  for a  period of six
years commencing at the  Effective Time, will, to  the extent permitted by  law,
maintain  all rights to indemnification now  existing in favor of the directors,
officers or  employees of  Biocraft  as provided  in Biocraft's  Certificate  of
Incorporation  or By-Laws with  respect to acts  and omissions occurring through
the Effective Time, and  Teva has guaranteed the  due and prompt performance  of
such  indemnification obligations of the  surviving corporation. During a period
of three years from the Effective Time, Teva will use its best efforts to  cause
Biocraft  to maintain the current policy or policies of directors' and officers'
liability insurance covering directors and officers of Biocraft with respect  to
acts  and omissions  occurring prior  to the  Effective Time;  provided that the
Surviving Corporation  may substitute  therefor policies  of at  least the  same
coverage  (with carriers comparable to  Biocraft's existing carriers) containing
terms and  conditions  which  are  no less  advantageous  to  the  officers  and
directors  and (ii)  the Surviving  Corporation shall not  be required  to pay a
premium at a rate  for such insurance  in excess of 150%  of the annual  premium
rate  represented  by the  last premium  paid prior  to the  date of  the Merger
Agreement, but in such case shall purchase as much coverage as possible for such
amount and (iii) any or all of  the officers and directors shall have the  right
to  provide funds to  the Surviving Corporation  to fund premiums  to the extent
they exceed such 150% level.
 
CERTAIN COVENANTS OF BIOCRAFT
 
     Biocraft has agreed, among  other things, that during  the period from  the
date  of  the  Merger  Agreement  until the  Effective  Time,  Biocraft  and its
subsidiaries will  conduct their  operations  in all  material respects  in  the
ordinary  and usual  course and  will use  their reasonable  efforts to preserve
intact their business  organizations, to  keep available the  services of  their
directors,  officers  and  employees,  preserve in  full  force  and  effect all
material  licenses  and  approvals  held  by  them  and  maintain   satisfactory
relationships  with suppliers, distributors, clients  and others having material
business relationships with them. In addition, Biocraft has agreed that  without
the  prior written consent of  Teva neither it nor  any of its subsidiaries will
during such  period (i)  make  any change  in or  amendment  to its  charter  or
by-laws;  (ii) issue or  sell any shares  of its capital  stock or share capital
(other than in connection with (A) Biocraft's Stockholder Dividend  Reinvestment
and  Stock Purchase Plan or  (B) the exercise of  options granted under employee
and directors'  stock  option  plans  outstanding on  the  date  of  the  Merger
Agreement)  or any of its other  securities, or issue any securities convertible
into, or options, warrants or rights to purchase or subscribe to, or enter  into
any  arrangement or contract with respect to the issuance or sale of, any shares
of its capital stock or any of  its other securities, or make any other  changes
in  its capital  structure; (iii)  declare, pay  or make  any dividend  or other
distribution or payment
 
                                       53
 
<PAGE>
 
<PAGE>
with respect to,  or split,  combine, redeem or  reclassify, any  shares of  its
capital  stock  or  share  capital  other  than  in  accordance  with Biocraft's
Restricted Stock Purchase  Plan or Shareholder  Dividend Reinvestment and  Stock
Purchase  Plan;  (iv) enter  into  any contract  or  commitment with  respect to
capital expenditures in excess of certain specified contracts or commitments  or
in  excess of  $100,000, individually, or  $200,000, in the  aggregate, or enter
into any  other  material  contracts  or commitments  except  contracts  in  the
ordinary  course of business; (v) acquire  assets (other than as contemplated by
clause (iv) above), other than in the ordinary course of business, in an  amount
in  excess of $100,000, individually, or  $200,000, in the aggregate, or dispose
of (including by way of sale, lease or encumbrance), other than in the  ordinary
course  of business, a  material amount of  assets or release  or relinquish any
material rights under any material contract; (vi) except as contemplated by  the
Merger  Agreement, amend any  employee or non-employee  benefit plan or program,
employment agreement,  license agreement  or retirement  agreement, or  pay  any
bonus  or contingent compensation, except in each case in the ordinary course of
business consistent  with  past  practice  prior  to  the  date  of  the  Merger
Agreement;  (vii)  incur  any indebtedness  for  borrowed money  (other  than by
drawing under current  revolving credit  agreements (as such  agreements are  in
effect  on the  date of  the Merger  Agreement and  without givingeffect  to any
waivers of any  of the  provisions of such  agreements)) or  guarantee any  such
indebtedness  or issue  or sell  any debt  securities or  warrants or  rights to
acquire any debt securities of Biocraft or any of its subsidiaries or  guarantee
any  debt securities of others; (viii) make any material change in its method of
accounting or record keeping  not otherwise required by  US GAAP; (ix) agree  to
the  settlement of any  material litigation for  any amounts in  excess of those
reserved on Biocraft's books and records;  or (x) purchase or acquire, or  offer
to  purchase  or  acquire,  any  shares of  its  capital  stock,  other  than in
connection with  Biocraft's  Restricted  Stock  Purchase  Plan  and  Stockholder
Dividend  Reinvestment  and  Stock  Purchase  Plan.  Until  the  Effective Time,
Biocraft has also  agreed, upon  reasonable notice, to  afford to  Teva and  its
authorized  representatives  reasonable  access  to  its  properties,  books and
records during normal  business hours and  to furnish information  as Teva  will
from time to time request.
 
CERTAIN COVENANTS OF TEVA
 
     Teva  has  agreed  that during  the  period  from the  date  of  the Merger
Agreement until the Effective Time, it  will (i) upon reasonable notice,  afford
Biocraft and its authorized representatives reasonable access to its properties,
books  and records  during normal business  hours and to  furnish information as
Biocraft will from time to time request;  (ii) make application to the Tel  Aviv
Stock  Exchange for the listing on such  exchange of the Teva Ordinary Shares to
be issued pursuant  to the Merger  Agreement; (iii) cause  the Teva ADSs  issued
pursuant to the Merger to be admitted for trading on the NASDAQ National Market,
subject  to official notice of issuance; and  (iv) exercise its rights under the
Irrevocable Proxy  to  vote  in the  Special  Meeting  in favor  of  the  Merger
Agreement  and the  Merger. Both  Biocraft and Teva  also agree  to cooperate in
filing the Registration Statement of which this Proxy Statement/Prospectus is  a
part  and to use their  best efforts to procure  its effectiveness. In addition,
Teva has agreed (a)  to indemnify the former  stockholders of Biocraft who  held
Biocraft  Common Stock  immediately prior to  the Effective Time  from, and hold
them harmless against, any federal, state, local and foreign tax liability  that
they   may  incur  if  Teva  or  any  of  its  affiliates  effects  any  merger,
consolidation,  reorganization,  issuance,  transfer,  assignment,   conveyance,
disposition  or other transaction with respect to the Surviving Corporation, its
capital stock or its assets after  the Effective Time, which, without regard  to
Section  367 of the  Code, results in the  Merger being treated  other than as a
tax-free reorganization under the Code and (b)  that it shall not (1) after  the
Effective  Time make any disposition of  the assets of the Surviving Corporation
or any equity  interest in  the Surviving  Corporation which  would prevent  the
Merger  from being recorded as a pooling of interest transaction or (2) prior to
the third anniversary (or a longer  period up to the fifth anniversary  provided
certain  conditions are met) of the Effective  Time, make any disposition of the
assets of the  Surviving Corporation or  any equity interests  in the  Surviving
Corporation  that would cause  any recognition of gain  under a gain recognition
agreement entered into with the Internal Revenue Service under Section 367(a) of
the Code  and Section  1.367(a)-3T of  the U.S.  Temporary Treasury  Income  Tax
Regulations  by  any  former stockholder  of  Biocraft  who is  a  'five percent
transferee shareholder' (as defined in Section 1.367(a)-3T(c)(6)(ii)), except  a
disposition described in Section 1.367(a)-3T(g)(7) as
 
                                       54
 
<PAGE>
 
<PAGE>
to  which Teva  provides the five  percent transferee shareholders,  on a timely
basis, with notice of the disposition and all information they require in  order
to comply with the requirements of subdivision (i) of that section.
 
NO SOLICITATION OF OTHER OFFERS
 
     Biocraft  and its subsidiaries shall not, directly or indirectly, take (nor
shall Biocraft  authorize  or  permit  its  subsidiaries,  officers,  directors,
investment  bankers, attorneys, or other representatives, to take) any action to
(i) solicit, initiate or encourage the  submission of any Takeover Proposal,  or
(ii) participate in any discussions or negotiations regarding, or furnish to any
person  any information with respect to, or  take any other action to facilitate
any inquiries or the making of any proposal that constitutes, or may  reasonably
be  expected to lead to, any Takeover  Proposal; provided, however, that, to the
extent required  by the  fiduciary  obligations of  the  Board of  Directors  of
Biocraft,  as determined in good faith by the Board of Directors after reviewing
the advice of outside counsel, Biocraft  may, (A) in response to an  unsolicited
request  therefor, furnish  information with respect  to Biocraft  to any person
pursuant to a customary confidentiality  agreement (as determined by  Biocraft's
outside  counsel) and  discuss (1)  such information (but  not the  terms of any
possible Takeover Proposal) and (2) the terms of the nonsolicitation  provisions
of  the Merger Agreement with such person and  (B) upon receipt by Biocraft of a
Takeover  Proposal,  following  delivery  to   Teva  of  the  notice   required,
participate  in discussions  or negotiations  regarding such  Takeover Proposal.
'Takeover  Proposal'  means  any  proposal  for  a  merger  or  other   business
combination  involving  Biocraft or  any  proposal or  offer  to acquire  in any
manner, directly or indirectly, an equity interest in, not less than 20% of  the
outstanding  voting securities of,  or assets representing not  less than 20% of
the annual revenues of Biocraft, other than the transactions contemplated by the
Merger Agreement.
 
     In the  event  the Board  of  Directors  of Biocraft  receives  a  Takeover
Proposal  that, in the  exercise of its fiduciary  obligations (as determined in
good faith  by the  Board of  Directors after  reviewing the  advice of  outside
counsel),  it determines to be  a Superior Proposal, the  Board of Directors may
(subject to  the  following  sentences)  withdraw  or  modify  its  approval  or
recommendation  of the Merger Agreement or  the Merger, approve or recommend any
such Superior Proposal, enter  into an agreement with  respect to such  Superior
Proposal  or terminate the Merger Agreement, in  each case at any time after the
second business day  following Teva's receipt  of written notice  (a 'Notice  of
Superior  Proposal') advising  Teva that the  Board of Directors  has received a
Superior Proposal, specifying the material terms and conditions of such Superior
Proposal and identifying  the person  making such  Superior Proposal.  'Superior
Proposal'  means any  bona fide  Takeover Proposal on  terms which  the Board of
Directors of Biocraft determines  in its good  faith reasonable judgment  (after
reviewing the advice of a financial advisor of nationally recognized reputation)
to be more favorable to Biocraft's stockholders than the Merger.
 
AMENDMENTS
 
     Any  provision of the Merger Agreement may  be amended or waived in writing
by the appropriate  parties thereto before  the Effective Time  (notwithstanding
any  stockholder approval) by action taken by the respective Boards of Directors
of Teva,  Merger Sub  and Biocraft,  provided that  after any  such  stockholder
approval,  no  such amendment  or waiver  shall  be made  which by  law requires
further approval by such stockholders without such further approval.
 
                                       55
 
<PAGE>
 
<PAGE>
                      DESCRIPTION OF TEVA ORDINARY SHARES
 
     The par value of  the Teva Ordinary  Shares is NIS 0.01  per share and  all
issued  and outstanding Teva Ordinary Shares  are fully paid and non-assessable.
Holders of paid-up Teva Ordinary Shares  are entitled to participate equally  in
the  payment  of  dividends  and  other  distributions  and,  in  the  event  of
liquidation,  in  all  distributions  after  the  discharge  of  liabilities  to
creditors.
 
     The  Teva Board of Directors may  declare interim dividends and propose the
final dividend with  respect to  any fiscal year  out of  profits available  for
dividends  after statutory appropriation  to capital reserves.  Declaration of a
final dividend  (not  exceeding  the  amount proposed  by  the  Board)  requires
shareholder  approval through the  adoption of an  ordinary resolution. All Teva
Ordinary Shares represented by the Teva  ADSs will be issued in registered  form
only. Teva Ordinary Shares do not entitle their holders to preemptive rights.
 
     Voting  is on the basis of one vote per share, either by a showing of hands
or, if the Chairman, two shareholders present in person, or shareholders present
in person or by proxy and holding  at least 5% of the outstanding share  capital
demand,  by secret ballot. An ordinary  resolution (for example, resolutions for
the approval of the  financial statements, the approval  of final dividends  and
the   appointment  of  auditors)   requires  a  majority   affirmative  vote  of
shareholders present  in  person or  by  proxy  but a  special  resolution  (for
example,  resolutions  amending  the  Articles  of  Association  and authorizing
changes in capitalization, and other major  changes as specified in the  Israeli
Companies  Ordinance) requires the  affirmative vote of  shareholders present in
person or by proxy and holding shares  conferring in the aggregate at least  75%
of  the  votes  actually cast  on  the  special resolution.  Certain  actions or
arrangements between major shareholders, directors and officers and Teva require
shareholder approval by majority vote. See 'COMPARISON OF STOCKHOLDER RIGHTS  --
Business Combinations'.
 
     Each  shareholder  (or shareholders)  of  outstanding Teva  Ordinary Shares
representing 4% of the fully  paid-up share capital has  the power to appoint  a
director.
 
     Neither  Teva's Memorandum of Association, the Articles of Association, nor
the laws of the State of Israel restrict  in any way the ownership or voting  of
Teva  Ordinary Shares by nonresidents or persons who are not citizens of Israel,
except with respect to citizens or residents of countries that are in a state of
war with Israel.
 
                   DESCRIPTION OF AMERICAN DEPOSITARY SHARES
 
     Set forth  below  is  a  summary  of  certain  provisions  of  the  Deposit
Agreement,  as amended  (the 'Deposit Agreement'),  among Teva, The  Bank of New
York, as depositary  (the 'Depositary'), and  the holders from  time to time  of
ADRs representing Teva ADSs. This summary does not purport to be complete and is
qualified  in its entirety  by the Deposit  Agreement, a copy  of which has been
incorporated by reference into  the Registration Statement  of which this  Proxy
Statement/Prospectus  forms a part.  Additional copies of  the Deposit Agreement
are available for inspection  at the Corporate Trust  Office of the  Depositary,
101  Barclay Street,  New York, New  York 10286,  and at the  principal Tel Aviv
office of Bank Leumi  Le-Israel Ltd., 2-4 Lilienblum  Street, Tel Aviv,  Israel,
and the principal Tel Aviv office of Israel Discount Bank Limited, 27-31 Yehunda
Halevi Street, Tel Aviv, Israel (collectively, the 'Custodian').
 
AMERICAN DEPOSITARY RECEIPTS
 
     ADRs  evidencing  a  specified number  of  Teva  ADSs are  issuable  by the
Depositary pursuant to the Deposit Agreement.  Each Teva ADS represents 10  Teva
Ordinary  Shares  (or evidence  of rights  to receive  10 Teva  Ordinary Shares)
deposited with the Custodian.
 
DEPOSIT AND WITHDRAWAL OF TEVA ORDINARY SHARES
 
     The Depositary has  agreed that, upon  deposit with the  Custodian of  Teva
Ordinary  Shares (or  evidence of rights  to receive such  Teva Ordinary Shares)
accompanied  by  an  appropriate  instrument  or  instruments  of  transfer   or
endorsement  in form  satisfactory to  the Custodian  and any  certifications as
 
                                       56
 
<PAGE>
 
<PAGE>
may be required by the Depositary or  the Custodian and subject to the terms  of
the  Deposit Agreement, the Depositary will execute and deliver at its Corporate
Trust Office,  upon payment  of the  fees,  charges and  taxes provided  in  the
Deposit  Agreement,  to or  upon  the written  order  of the  person  or persons
entitled thereto, an ADR registered  in the name of  such person or persons  for
the number of Teva ADSs issuable in respect of such deposit.
 
     Every  person depositing Teva  Ordinary Shares under  the Deposit Agreement
shall be deemed to represent and warrant that such Teva Ordinary Shares and each
certificate  therefor  are   validly  issued,  fully   paid,  nonassessable   of
outstanding Teva Ordinary Shares and that such person is duly authorized to make
such deposit, and the deposit of such Ordinary Shares or sale of ADRs evidencing
Teva ADSs by that person is not restricted under the Securities Act.
 
     Upon surrender of ADRs at the Corporate Trust Office of the Depositary, and
upon  payment of the fees  provided in the Deposit  Agreement and subject to the
terms and  conditions of  the Deposit  Agreement, ADR  holders are  entitled  to
delivery to them or upon their order at the principal office of the Custodian or
at the Corporate Trust Office of the Depositary of certificates representing the
Teva  Ordinary  Shares  and any  other  securities,  property or  cash  that the
surrendered ADRs evidence the right to receive. Delivery to the Corporate  Trust
Office of the Depositary shall be made at the risk and expense of the ADR holder
surrendering ADRs.
 
     The  Depositary may execute and  deliver ADRs prior to  the receipt of Teva
Ordinary Shares ('Pre-Release'). The Depositary may deliver Teva Ordinary Shares
upon the receipt and cancellation of  ADRs that have been Pre-Released,  whether
or  not such cancellation is prior to the termination of such Pre-Release or the
Depositary knows that such ADR has  been Pre-Released. Each Pre-Release will  be
(a)  accompanied by a written representation from the person to whom ADRs are to
be delivered that such person, or its customer, owns the Teva Ordinary Shares or
ADRs to be remitted, as the case  may be, (b) at all times fully  collateralized
with  cash or  such other  collateral as  the Depositary  deems appropriate, (c)
terminable by the Depositary  on not more than  five (5) business days'  notice,
and  (d)  subject to  such  further indemnities  and  credit regulations  as the
Depositary deems appropriate. The number of Teva ADSs outstanding at any time as
a result of Pre-Releases  will not normally exceed  thirty percent (30%) of  the
Teva  Ordinary Shares deposited with the Depositary; provided, however, that the
Depositary reserves the  right to change  or disregard such  limit from time  to
time as it deems appropriate.
 
DIVIDENDS, OTHER DISTRIBUTIONS AND RIGHTS
 
     The  Depositary is required to  convert or cause to  be converted into U.S.
dollars, to the extent that in its judgment  it can do so on a reasonable  basis
and  can transfer  the resulting  U.S. dollars  to the  United States,  all cash
dividends and other cash distributions denominated in a currency other than U.S.
dollars that it receives in respect  of the deposited Teva Ordinary Shares,  and
to distribute the amount received, subject to the terms of the Deposit Agreement
and  net  of  any  expenses  incurred  by  the  Depositary  in  connection  with
conversion, to the holders of ADRs in proportion to the number of Teva ADSs that
are evidenced  by such  ADRs. The  amount  distributed will  be reduced  by  any
amounts  to be withheld  by Teva or  the Depositary for  applicable taxes net of
expenses of conversion into U.S. dollars.  If the Depositary determines that  in
its  reasonable  judgment  any foreign  currency  received  by it  cannot  be so
converted on a reasonable basis and transferred, or if any required approval  or
license  of any government or agency thereof  is denied or not obtained within a
reasonable period of time  as determined by the  Depositary, the Depositary  may
distribute  such foreign currency  (or an appropriate  document evidencing their
right to receive such  foreign currency) received by  it or, in its  discretion,
hold such foreign currency uninvested and without liability for interest thereon
for  the respective accounts of the ADR holders entitled to receive the same. If
any conversion of foreign currency, in whole or in part, cannot be effected  for
distribution to some of the holders of ADRs entitled thereto, the Depositary may
in  its discretion make such conversion and  distribution in U.S. dollars to the
extent permissible to the  holders of ADRs entitled  thereto and may  distribute
the  balance of the  foregoing currency received  by the Depositary  to, or hold
such balance  uninvested and  without  liability for  interest thereon  for  the
respective accounts of the holders of ADRs entitled thereto.
 
                                       57
 
<PAGE>
 
<PAGE>
     If  any  distribution upon  any Teva  Ordinary  Shares deposited  or deemed
deposited under  the  Deposit Agreement  consists  of  a dividend  in,  or  free
distribution  of, additional Teva Ordinary Shares, the Depositary shall, only if
Teva so  requests,  distribute  to  the holders  of  outstanding  ADRs  entitled
thereto,  in proportion to  the number of  Teva ADSs that  are evidenced by such
ADRs, additional ADRs evidencing an aggregate number of Teva ADSs that represent
the  number  of  Teva  Ordinary  Shares  received  as  such  dividend  or   free
distribution  subject to  the terms  of the Deposit  Agreement. In  lieu of Teva
delivering ADRs for fractional Teva ADSs in the event of any such  distribution,
the  Depositary will sell the amount of  Teva Ordinary Shares represented by the
aggregate of such fractions and will  distribute the net proceeds to holders  of
ADRs  in accordance with  the Deposit Agreement.  If additional ADRs  are not so
distributed, each Teva ADS shall  thereafter also represent the additional  Teva
Ordinary  Shares distributed together with  the Teva Ordinary Shares represented
by such Teva ADS prior to such distribution.
 
     If Teva offers  or causes to  be offered  to the holders  of Teva  Ordinary
Shares any rights to subscribe for additional Teva Ordinary Shares or any rights
of any other nature, the Depositary shall have discretion as to the procedure to
be  followed in making such rights available  to holders of ADRs or in disposing
of such rights  for the  benefit of  such holders  and making  the net  proceeds
available  to such holders  or, if the  Depositary may neither  make such rights
available nor dispose of such rights and make the net proceeds available to such
holders, the Depositary shall allow the rights to lapse; provided, however, that
the Depositary will, if requested by Teva, take action as follows (i) if at  the
time  of the offering of any rights  the Depositary determines in its discretion
that it is lawful and feasible to  make such rights available to all holders  of
ADRs  or  to certain  holders of  ADRs but  not  to other  holders of  ADRs, the
Depositary may  distribute to  any holder  of  ADRs to  whom it  determines  the
distribution to be lawful and feasible, in proportion to the number of Teva ADSs
held by such holder of ADRs, warrants or other instruments therefor in such form
as  it deems appropriate or (ii) if  the Depositary determines in its discretion
that it is  not lawful and  feasible to  make such rights  available to  certain
holders  of  ADRs, it  may sell  the  rights, warrants  or other  instruments in
proportion to the number of Teva ADSs held by the holder of ADRs to whom it  has
determined  it  may not  lawfully  or feasibly  make  such right  available, and
allocate the net proceeds of such sales  (net of the fees of the Depositary  and
all  taxes and  governmental charges  and subject  to the  terms of  the Deposit
Agreement) for the account  of such holders of  ADRs otherwise entitled to  such
rights, warrants or other instruments, upon an averaged or other practical basis
without  regard  to  any distinctions  among  such  holders of  ADRs  because of
exchange restrictions  or the  date of  delivery of  any ADR  or otherwise.  The
Depositary  shall not be responsible for any failure to determine that it may be
lawful and feasible to make such rights available to holders of ADRs in  general
or any holder in particular.
 
     If  a  holder  of  ADRs  requests the  distribution  of  warrants  or other
instruments in order to exercise the rights  allocable to the Teva ADSs of  such
holder,  the  Depositary will  make such  rights available  to such  holder upon
written notice from Teva  to the Depositary  that Teva has  elected in its  sole
discretion  to permit such rights  to be exercised and  such holder has executed
such documents as  Teva has  determined in  its sole  discretion are  reasonably
required  under applicable  law. Upon instruction  pursuant to  such warrants or
other instruments to the  Depositary from such holder  to exercise such  rights,
upon  payment by such holder to the Depositary for the account of such holder of
an amount equal to the purchase price of the Teva Ordinary Shares to be received
upon the exercise of the rights, and upon payment of the fees of the  Depositary
as  set forth in  such warrants or  other instruments, the  Depositary shall, on
behalf of  such holder,  exercise  the rights  and  purchase the  Teva  Ordinary
Shares,  and  Teva shall  cause  the Teva  Ordinary  Shares so  purchased  to be
delivered to the Depositary on behalf of such holder. As agent for such  holder,
the  Depositary will cause the Teva Ordinary Shares so purchased to be deposited
under the Deposit Agreement, and shall issue and deliver to such holder legended
ADRs, restricted as to transfer under applicable securities laws.
 
     The Depositary  will  not  offer to  the  holders  of ADRs  any  rights  to
subscribe  for additional  Teva Ordinary Shares  or rights of  any other nature,
unless and until such a registration statement is in effect with respect to  the
rights  and the securities to which they relate, or unless the offering and sale
of such securities  to the  holders of such  ADRs are  exempt from  registration
under   the  provisions  of  the  Securities  Act  and  an  opinion  of  counsel
satisfactory to the Depositary and Teva has been obtained.
 
                                       58
 
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<PAGE>
     If the Depositary determines that  any distribution of property in  respect
of  the  Teva  Ordinary Shares  (including  Teva  Ordinary Shares  or  rights to
subscribe therefor) is subject to any tax or other governmental charge that  the
Depositary  is obligated  to withhold, the  Depositary may be  public or private
sale in Israel  dispose of  all or  a portion  of such  property including  Teva
Ordinary  Shares and Rights  to subscribe therefor  in such amounts  and in such
manner as the Depositary deems necessary  and practicable to pay any such  taxes
or charges, and the Depositary will distribute the net proceeds of any such sale
and after deduction of any taxes or charges to the ADR holders entitled thereto.
 
     Subject  to the terms of the Deposit  Agreement, upon any change in nominal
value,  change   in   par   value,  split-up,   consolidation   or   any   other
reclassification   of  Teva  Ordinary  Shares,  or  upon  any  recapitalization,
reorganization, merger or consolidation or sale  of assets affecting Teva or  to
which  it is a party, any securities that shall be received by the Depositary or
the Custodian in exchange for or in conversion of or in respect of Teva Ordinary
Shares shall  be treated  as  newly deposited  Teva  Ordinary Shares  under  the
Deposit  Agreement,  and  Teva ADSs  shall  thenceforth represent  the  new Teva
Ordinary  Shares  so  received  in  respect  of  Teva  Ordinary  Shares,  unless
additional  ADRs  are delivered  or the  Depositary calls  for the  surrender of
outstanding ADRs to be exchanged for new ADRs.
 
RECORD DATES
 
     Whenever any cash dividend or other cash distribution shall become payable,
and distribution other than cash  shall be made or  rights shall be issued  with
respect  to the Teva Ordinary Shares, or  whenever for any reason the Depositary
causes a change in the  number of Teva Ordinary  Shares that are represented  by
each Teva ADS, or whenever the Depositary shall receive notice of any meeting of
holders  of Teva Ordinary Shares, the Depositary shall fix a record date (a) for
the determination of the holders  of ADRs who shall  be entitled (i) to  receive
such  dividend, distribution or rights, or the net proceeds of the sale thereof,
or (ii) to  give instructions  for the  exercise of  voting rights  at any  such
meeting,  or (b)  on or  after which  each Teva  ADS will  represent the changed
number of Teva Ordinary Shares.
 
REPORTS AND OTHER COMMUNICATIONS
 
     Teva will  furnish to  the  Depositary and  the  Custodian all  notices  of
shareholders'  meetings  and  other  reports and  communications  that  are made
generally  available  to  the  holders  of  Teva  Ordinary  Shares  and  English
translations  of the  same. The Depositary  will make such  notices, reports and
communications available for inspection  by ADR holders  at its Corporate  Trust
Office  when  furnished by  Teva  pursuant to  the  Deposit Agreement  and, upon
request by  Teva, will  mail such  notices, reports  and communications  to  ADR
holders at Teva's expense.
 
VOTING OF THE UNDERLYING TEVA ORDINARY SHARES
 
     Upon  receipt  of notice  of  any meeting  or  solicitation of  consents or
proxies of  holders  of Teva  Ordinary  Shares,  if requested  in  writing,  the
Depositary  shall, as soon as practicable thereafter,  mail to the ADR holders a
notice containing (a) such information as is contained in the notice received by
the Depositary and (b) a statement that the  holders of ADRs as of the close  of
business  on a specified record date will be entitled, subject to applicable law
and the provisions  of the Memorandum  and Articles of  Association of Teva,  to
instruct  the Depositary as to the exercise of voting rights, if any, pertaining
to the amount of Teva Ordinary Shares represented by their respective Teva ADSs.
Upon the written request of  an ADR holder on such  record date, received on  or
before  the date established by the  Depositary for such purpose, the Depositary
shall endeavor, insofar as is practicable and permitted under applicable law and
the provisions of the Memorandum and Articles of Association of Teva, to vote or
cause to be voted  the amount of  Teva Ordinary Shares  represented by the  Teva
ADSs evidenced by such ADR in accordance with the instructions set forth in such
request.  If no instructions are received by  the Depositary from a holder of an
ADR, the Depositary  shall give a  discretionary proxy for  the Ordinary  Shares
represented by such holder's ADR to a person designated by Teva.
 
                                       59
 
<PAGE>
 
<PAGE>
AMENDMENT AND TERMINATION OF THE DEPOSIT AGREEMENT
 
     The form of the ADRs and the terms of the Deposit Agreement may at any time
be  amended by  agreement between  Teva and  the Depositary.  Any amendment that
imposes or increases any fees or charges (other than taxes or other governmental
charges), or that otherwise prejudices any substantial existing right of holders
of ADRs  shall, however,  not become  effective until  the expiration  of  three
months  after  notice  of  such  amendment has  been  given  to  the  holders of
outstanding ADRs. Every  holder of  an ADR at  the time  such amendment  becomes
effective  will be deemed, by continuing to  hold such ADR, to consent and agree
to such amendment and to be bound  by the Deposit Agreement as amended  thereby.
In  no event will any amendment impair the  right of any ADR holder to surrender
the ADRs held by such holder  and receive therefor the underlying Teva  Ordinary
Shares  and any  other property represented  thereby, except in  order to comply
with mandatory provisions of applicable law.
 
     Whenever so directed by  Teva, the Depositary has  agreed to terminate  the
Deposit  Agreement by mailing notice  of such termination to  the holders of all
ADRs then outstanding at least  30 days prior to the  date fixed in such  notice
for  such  termination.  The  Depositary  may  likewise  terminate  the  Deposit
Agreement if at any time 60 days  shall have expired after the Depositary  shall
have  delivered to the holders  of all ADRs then  outstanding and Teva a written
notice of its election to resign and a successor depositary shall not have  been
appointed and accepted its appointment. On and after the date of termination, an
ADR  holder, upon  surrender of such  ADR at  the Corporate Trust  Office of the
Depositary, upon payment of the fees of the Depositary, and upon payment of  any
applicable  tax or governmental charges, will be  entitled to delivery to him or
upon his  order  of  the amount  of  Teva  Ordinary Shares  and  other  property
represented  by  such ADR.  If any  ADRs  remain outstanding  after the  date of
termination, the  Depositary thereafter  will  discontinue the  registration  of
transfers  of ADRs,  will suspend the  distribution of dividends  to the holders
thereof and will not give any further notices or perform any further acts  under
the  Deposit  Agreement,  except  (i)  the  collection  of  dividends  and other
distributions, (ii)  the  sale of  rights  and  other property,  and  (iii)  the
delivery  of  Teva  Ordinary  Shares,  together  with  any  dividends  or  other
distributions received with respect thereto and the net proceeds of the sale  of
any  rights or other property, in exchange  for surrendered ADRs, subject to the
terms of the Deposit  Agreement. At any  time after the  expiration of one  year
from  the  date of  termination,  the Depositary  may  sell the  underlying Teva
Ordinary Shares and  hold uninvested the  net proceeds, together  with any  cash
then  held by it under the Deposit Agreement, unsegregated and without liability
for interest, for  the pro rata  benefit of the  holders of ADRs  that have  not
theretofore  surrendered  their  ADRs  and  such  holders  shall  become general
creditors of the Depositary with respect to such net proceeds. After making such
sale, the Depositary shall be discharged from all obligations under the  Deposit
Agreement,  except to account  for net proceeds and  other cash (after deducting
certain  fees  of  the  Depositary)  and  except  for  certain  obligations  for
indemnification  set forth in the Deposit Agreement. Upon the termination of the
Deposit Agreement, Teva will also be discharged from all obligations thereunder,
except for certain obligations to the Depositary.
 
CHARGES OF DEPOSITARY
 
     Teva will pay the  fees, reasonable expenses  and out-of-pocket charges  of
the  Depositary and those of any registrar only in accordance with agreements in
writing entered into  between the  Depositary and Teva  from time  to time.  The
following  charges shall be incurred by any party depositing or withdrawing Teva
Ordinary Shares or by  any party surrendering  ADRs or to  whom ADRs are  issued
(including,  without limitation, issuance pursuant to  a stock dividend or stock
split declared by Teva or an exchange  of stock regarding the ADRs or  deposited
Teva  Ordinary Shares  or a distribution  of ADRs  pursuant to the  terms of the
Deposit Agreement):  (i)  the fees  of  the  Depositary for  the  execution  and
delivery,   transfer,  or  surrender  of  ADRs,   or  the  making  of  any  cash
distribution, pursuant to the Deposit  Agreement, (ii) any applicable taxes  and
other  governmental charges, (iii) any applicable transfer or registration fees,
(iv) certain cable, telex and facsimile transmission charges as provided in  the
Deposit  Agreement,  (v)  any expenses  incurred  in the  conversion  of foreign
currency and (vi) a fee of $5.00 or  less per 100 ADRs (or portion thereof)  for
the  delivery of ADRs in connection with  the deposit of Teva Ordinary Shares or
distributions on Teva Ordinary Shares on  the surrender of ADRs. The  Depositary
 
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<PAGE>
 
<PAGE>
has  advised  Teva  that  it will  waive  the  fee described  in  (vi)  above in
connection with the issuance of ADRs contemplated by the Merger.
 
     The Depositary, subject to the Deposit  Agreement, may own and deal in  any
class of securities of Teva and its affiliates and in ADRs.
 
LIABILITY OF HOLDERS FOR TAXES, DUTIES OR OTHER CHARGES
 
     Any  tax or other governmental charge with respect to ADRs or any deposited
Teva Ordinary Shares represented by  any ADR shall be  payable by the holder  of
such ADR to the Depositary. The Depositary may refuse to effect transfer of such
ADR  or any withdrawal of deposited Teva Ordinary Shares represented by such ADR
until  such  payment  is  made,  and   may  withhold  any  dividends  or   other
distributions  or may sell for the account of the holder thereof any part or all
of the deposited Teva Ordinary Shares represented by such ADR and may apply such
dividends or distributions or the  proceeds of any such  sale in payment of  any
such  tax or other governmental  charge and the holder  of such ADR shall remain
liable for any deficiency.
 
TRANSFER OF AMERICAN DEPOSITARY RECEIPTS
 
     The ADRs are transferable on the books of the Depositary, provided that the
delivery of ADRs against deposits of  Teva Ordinary Shares generally or  against
deposits of particular Teva Ordinary Shares may be suspended, or the transfer of
ADRs  in particular instances may be refused, or the registration of transfer of
outstanding ADRs generally may be suspended, during any period when the transfer
books of the Depositary are closed, or if any such action is deemed necessary or
advisable by the Depositary or Teva at any time or from time to time because  of
any  requirement of law or of any government or governmental body or commission,
or under  any provision  of the  Deposit  Agreement, or  for any  other  reason,
subject to the terms of the Deposit Agreement. The surrender of outstanding ADRs
and  withdrawal of deposited  Teva Ordinary Shares may  not be suspended subject
only to  (i)  temporary delays  caused  by closing  the  transfer books  of  the
Depositary  or  Teva, the  deposit of  Teva Ordinary  Shares in  connection with
voting at a shareholders' meeting or the payment of dividends, (ii) the  payment
of  fees, taxes and similar charges and  (iii) compliance with the United States
or foreign  laws or  governmental regulations  relating to  the ADRs  or to  the
withdrawal  of the  deposited Teva  Ordinary Shares.  Without limitation  of the
foregoing, the  Depositary shall  not  knowingly accept  for deposit  under  the
Deposit  Agreement any Teva Ordinary Shares  required to be registered under the
provisions of the Securities Act, unless  a registration statement is in  effect
as  to such Teva Ordinary Shares. As  a condition precedent to the execution and
delivery, registration of  transfer, split-up, combination  or surrender of  any
ADR  or withdrawal of Teva Ordinary Shares, the Depositary, the Custodian or the
registrar may  require  payment  from  the person  presenting  the  ADR  or  the
depositor  of the Teva Ordinary  Shares of a sum  sufficient to reimburse it for
any tax or other governmental charge and any stock transfer or registration  fee
with  respect thereto, payment of any applicable  fees payable by the holders of
ADRs, may require the production of  proof satisfactory to the Depositary as  to
the  identity and genuineness  of any signature and  may also require compliance
with any regulations the Depositary may establish consistent with the provisions
of the Deposit Agreement. The Depositary may refuse to execute and deliver ADRs,
register the transfer of  any ADR or  make any distribution  on, or related  to,
Teva Ordinary Shares until it or the Custodian has received proof of citizenship
or  residence, exchange  control approval  or other  information as  it may deem
necessary or  proper. Holders  of ADRs  may inspect  the transfer  books of  the
Depositary  at any reasonable time, provided,  that such inspection shall not be
for the purpose  of communicating  with holders  of ADRs  in the  interest of  a
business  or object other than  the business of Teva or  a matter related to the
Deposit Agreement or ADRs.
 
GENERAL
 
     Neither the  Depositary nor  Teva  nor any  of their  directors,  officers,
employees,  agents or  affiliates will be  liable to  the holders of  ADRs if by
reason of any present or  future law or regulation of  the United States or  any
other  country  or  of  any  government or  regulatory  authority  or  any stock
exchange,
 
                                       61
 
<PAGE>
 
<PAGE>
any  provision,  present  or  future,  of  Teva's  Memorandum  and  Articles  of
Incorporation  or any circumstance beyond its control, the Depositary or Teva or
any of their respective directors, officers, employees, agents or affiliates  is
prevented  or delayed in performing its obligations or exercising its discretion
under the Deposit Agreement or  is subject to any  civil or criminal penalty  on
account  of  performing  its  obligations.  The  obligations  of  Teva  and  the
Depositary under the Deposit Agreement are expressly limited to performing their
obligations specifically set forth in  the Deposit Agreement without  negligence
or bad faith.
 
                        COMPARISON OF STOCKHOLDER RIGHTS
 
     The  following is a  summary of material differences  between the rights of
holders of Biocraft Common Stock and holders of Teva Ordinary Shares and between
the Delaware  General Corporation  Law (the  'DGCL') and  the Israeli  Companies
Ordinance  (the 'Companies Ordinance') which may affect the rights and interests
of stockholders.
 
VOTE REQUIRED FOR CERTAIN ACTIONS
 
     Under the DGCL, a merger, consolidation,  sale of all or substantially  all
assets,  dissolution or  amendment to the  certificate of  incorporation must be
approved by vote at a meeting at which a quorum is present or by written consent
of a majority of the outstanding shares entitled to vote thereon (except mergers
involving a corporation and its subsidiary in which the parent corporation  owns
at  least 90%  of the  outstanding shares  of the  subsidiary, in  which case no
stockholder vote or written consent is required).
 
     Under the  Companies  Ordinance,  settlements and  arrangements  between  a
company  and  any class  of its  shareholders  (or any  class of  its creditors)
involving certain  types  of  mergers,  reorganizations,  sales  of  assets  and
dissolutions  require (i) the approval at an extraordinary meeting of a majority
in number of the shareholders representing  75% of the relevant class of  shares
present  and voting in person or by proxy, and (ii) the sanction of the District
Court. Once so approved and sanctioned,  all shareholders of the relevant  class
are  bound by the arrangement. The  Companies Ordinance also provides that where
an offer is made by  one company (the 'Offering  Company') via plan or  contract
for  all the shares, or a class  of shares, of another company, and shareholders
of such company holding at least nine-tenths of the value of such shares approve
such plan  or  such contract  within  four months  after  it was  proposed,  the
Offering  Company may, within  two months of reaching  the nine-tenths level, by
notice require dissenting shareholders to transfer their shares on the terms  of
the  plan or contract. A dissenting shareholder  may apply to the District Court
within one month of the date on which notice was given objecting to the transfer
on the proposed terms. The District  Court may order that the shareholder  shall
not  be  required to  transfer  his shares,  or may  specify  such terms  of the
transfer as it finds appropriate. For  the vote required for other actions,  see
'DESCRIPTION OF TEVA ORDINARY SHARES'.
 
APPRAISAL RIGHTS
 
     Under the DGCL, a stockholder of a constituent corporation in a merger may,
under  certain circumstances and upon meeting certain requirements, dissent from
the merger by demanding payment  in cash for his/her  shares equal to the  'fair
value'  (excluding  any  appreciation or  depreciation  as a  consequence  or in
expectation of the transaction) of such shares, as determined by agreement  with
the corporation or by an independent appraiser appointed by a court in an action
timely brought by the corporation or the dissenters.
 
     Delaware  law  grants  dissenters' appraisal  rights  only in  the  case of
certain mergers  and not  in the  case of  a sale  or transfer  of assets  or  a
purchase  of assets for stock  regardless of the number  of shares being issued.
Delaware law does not grant  appraisal rights in a  merger to holders of  shares
listed  on a  national securities  exchange or  designated as  a national market
system security by the National Association of Securities Dealers, Inc. or  held
of  record by more  than 2,000 shareholders  unless the plan  of merger converts
such shares into anything other than stock of the surviving corporation or stock
of another corporation  which is  listed on  a national  securities exchange  or
designated  as a national market system  security by the National Association of
Securities   Dealers,    Inc.    or    held   of    record    by    more    than
 
                                       62
 
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<PAGE>
2,000  shareholders (or cash in lieu of fractional shares or some combination of
the above).  Therefore, as  described under  'THE MERGER  -- Appraisal  Rights,'
appraisal rights will not be available to Biocraft stockholders in the Merger.
 
     While the Companies Ordinance does not provide for appraisal rights per se,
if  a shareholder applies to  a court as described under  ' -- Vote Required for
Certain Actions,' the  court may  specify the terms  for the  acquisition as  it
deems appropriate.
 
STOCKHOLDERS' MEETING
 
     Under  the DGCL, meetings of stockholders may  be held at such place as may
be designated  by or  in  the manner  provided  in the  by-laws  or, if  not  so
designated,  at  the  registered  office of  the  corporation  in  Delaware. The
stockholder meetings may be held within Delaware or outside Delaware. An  annual
meeting  of stockholders  is specifically  mandated by  the DGCL,  which directs
every corporation to  convene a  meeting of  its stockholders  annually for  the
election  of directors on a date either designated in its bylaws or fixed in the
manner provided in the bylaws. Under the Biocraft By-laws, an annual meeting  of
stockholders must be held once in every calendar. All other meetings are special
meetings as is discussed below. The presence of the holders of a majority of the
outstanding  shares  of  Biocraft  Common Stock  constitutes  a  quorum  for all
stockholder meetings.
 
     Under the Companies Ordinance, a  general meeting of the shareholders  must
be held at least once in every calendar year within a period of not more than 15
months  following the last  preceding general meeting. The  place of the meeting
may be either within  or without Israel.  If no meeting  was held, the  District
Court  may, upon application  by a shareholder,  convene a meeting  or order the
convening of a  meeting. All  meetings of  the shareholders  other than  general
meetings are extraordinary meetings as discussed below. The presence of at least
two  shareholders  at a  general  meeting holding  ten  percent or  more  of the
outstanding share capital of Teva  constitutes a quorum. Notice to  shareholders
of at least seven days is required for all general and extraordinary meetings of
the  shareholders, unless a special  resolution is to be  proposed in which case
notice of at least twenty-one days is required.
 
ACTION BY WRITTEN CONSENT OF STOCKHOLDERS
 
     Under the DGCL, unless a  certificate of incorporation provides  otherwise,
stockholders  may take  action by  written consent without  a meeting  as to any
matter for which stockholder  approval is required or  which is permitted to  be
taken  based on the approval of stockholders. Action by written consent requires
the consent of a percentage of all the outstanding shares eligible to vote equal
to the percentage  that would  be required for  approval by  shares present  and
voting   at  a  meeting.  Under   the  Biocraft  Certificate  of  Incorporation,
stockholders may take  action by  written consent without  a meeting  as to  any
matter  for which stockholder approval  is required or which  is permitted to be
taken on the approval of stockholders.
 
     Under Israeli law,  the articles  of association  of a  company may  permit
action  by written consent of shareholders  without a meeting. However, the Teva
Articles of Association do not permit action by written consent.
 
ELECTION OF DIRECTORS; CLASSES OF DIRECTORS; CUMULATIVE VOTING
 
     Under the DGCL, a corporation's board  of directors must consist of one  or
more  members, with the number fixed by the corporation's by-laws or certificate
of incorporation. Under the  DGCL, directors are elected  by a plurality of  the
votes  of shares represented by proxy at a  meeting at which a quorum is present
and entitled to vote on the election of directors, and may be divided into  one,
two or three classes. Under the Biocraft Certificate of Incorporation, the board
of  directors of Biocraft shall consist of  not less than six members, the exact
number to be determined by resolution of the Board. The Biocraft Board currently
has ten members. The Biocraft Certificate of Incorporation further provides that
directors shall be classified with respect  to the time for which each  director
holds  office into three classes. Each  class of directors of Biocraft consists,
as  nearly  as  possible,  of  one-third  of  the  total  number  of   directors
constituting  the entire Biocraft Board. A class of directors is elected at each
 
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<PAGE>
annual meeting of  stockholders. Each Biocraft  director is elected  to serve  a
three-year  term. The presence of a majority of directors in office constitute a
quorum for transacting business.
 
     Under the DGCL, cumulative  voting is not available  unless so provided  in
the  corporation's  certificate of  incorporation.  The Biocraft  Certificate of
Incorporation does not provide for cumulative voting.
 
     Under the Companies  Ordinance, a  public company  must have  at least  two
directors.  Under the Teva Articles of Association, the Teva Board is to consist
of a minimum of seven directors, the exact number to consist of the aggregate of
the directors appointed or elected as follows: (i) each shareholder or group  of
shareholders  holding 4% of the outstanding  Teva Ordinary Shares is entitled to
appoint one director for a term of  one year; (ii) the President of Teva  serves
as  a member of the  Board during the period of  his service as President; (iii)
the Companies Ordinance requires  two independent public  directors to serve  as
members  of Teva's Board for a term of five years; and (iv) additional directors
(the number of which is determined from time to time by the Board, provided that
such number may not exceed 15) are elected by Teva's shareholders at the  annual
general  meeting  of  shareholders  to  serve  for  three-year  staggered  terms
('Additional Directors'). There are currently 26  members on the Board of  Teva.
Under  the Teva Articles of Association, unless otherwise determined by the Teva
Board of Directors,  the presence of  seven directors constitutes  a quorum  for
transacting  business. The  Teva Ordinary Shares  do not  have cumulative voting
rights.
 
     Under the Companies  Ordinance, public Israeli  companies whose shares  are
traded  in Israel  must appoint  two 'directors  from the  public' for five-year
terms and  an 'audit  committee.' Teva  is  subject to  and complies  with  such
requirements.
 
NEWLY CREATED DIRECTORSHIPS AND VACANCIES
 
     Delaware law provides that, unless otherwise provided in the certificate of
incorporation  or  by-laws, vacancies  and  newly created  directorships  may be
filled by majority vote of the directors  then in office, even if the number  of
directors  then in office is less than a quorum. In addition, if, at the time of
filling any vacancy or newly created directorship, the directors then in  office
constitute  less  than a  majority of  the  whole board,  the Delaware  Court of
Chancery may,  upon application  of stockholders  holding at  least 10%  of  the
shares outstanding at the time and entitled to vote, summarily order an election
to  be held  to fill any  such vacancies  or newly created  directorships, or to
replace the directors chosen by the directors then in office. Such elections are
to be conducted in accordance with  the procedures provided by Delaware law  for
holding stockholder meetings.
 
     Under  the Teva Articles of Association, the  Board is entitled at any time
to elect  Additional  Directors to  serve  until the  following  annual  general
meeting  of  shareholders  (subject  to  the  maximum  number  of  15 Additional
Directors). Vacancies  in the  Teva  Board may  be filled  by  the vote  of  the
majority  of the directors holding office in certain specified circumstances. If
the number of directors is less than the minimum number, then the directors  may
either  fill the vacancy or  convene a general meeting  of the shareholders, but
may take no other  directorial action until the  minimum number of directors  is
achieved.  In the event of  one or more vacancies in  the Teva Board not causing
the number of  directors to  be less than  the minimum  required, the  directors
shall  continue to  fulfill all their  directorial duties. The  Teva Articles of
Association  also  provide  a  procedure  for  the  appointment  of   substitute
directors.
 
REMOVAL OF DIRECTORS
 
     Under   the  DGCL,  unless   provided  otherwise  in   the  certificate  of
incorporation, in the case of a  corporation whose board is classified (such  as
Biocraft), a director can be removed only for cause by the holders of a majority
of  shares  then  entitled  to  vote in  an  election  of  directors. Biocraft's
certificate of incorporation does not  provide for removal of directors  without
cause.
 
     Under the Teva Articles of Association, the holders of seventy-five percent
of  the voting power  represented at a  general meeting entitled  to so vote may
remove any director.
 
                                       64
 
<PAGE>
 
<PAGE>
DIVIDENDS
 
     The DGCL provides that  a corporation may,  unless otherwise restricted  by
its  certificate of incorporation, declare and  pay dividends out of surplus, as
defined in the DGCL, or if no surplus exists, out of net profits for the current
or preceding fiscal year (provided that the amount of capital of the corporation
following the  declaration and  payment of  the dividend  is not  less than  the
aggregate  amount of the capital represented by the issued and outstanding stock
of  all  classes  having  a   preference  upon  the  distribution  of   assets).
Additionally,  the DGCL provides that a corporation may redeem or repurchase its
shares.
 
     The Companies Ordinance does not define the source from which dividends may
be paid, although common law generally applied by the courts of Israel has  been
interpreted  to require that dividends  be paid solely out  of profits. The Teva
Articles of Association provide  that no dividend shall  be paid otherwise  than
out of the profits of Teva.
 
TREASURY SHARES
 
     Under  the DGCL, Biocraft may directly or indirectly acquire its own shares
and hold such  shares in  treasury, although  such shares  may not  be voted  or
counted for quorum purposes.
 
     Under  Israeli law,  Teva cannot acquire  its own shares  except in certain
limited circumstances.
 
BUSINESS COMBINATIONS
 
     Delaware law prevents an 'interested stockholder' (defined as a holder  who
acquires  15% or more  of a corporation's  stock) from entering  into a business
combination with a corporation within three years after the date the stockholder
acquired such corporation's stock. However, a business combination is  permitted
(i)  if prior to the date the  stockholder became an interested stockholder, the
board of directors of the  corporation approved either the business  combination
or  such acquisition of stock,  (ii) if, at the  time the interested stockholder
acquired such 15% interest, it acquired 85% or more of the outstanding stock  of
the  corporation, excluding shares  held by directors who  are also officers and
shares held  under  certain employee  stock  plans,  or (iii)  if  the  business
combination  is approved by the corporation's  board of directors and two-thirds
of  the  outstanding  shares  voting  at   an  annual  or  special  meeting   of
stockholders,   excluding  shares  held  by  the  interested  stockholder.  This
provision  applies   automatically  to   Delaware  corporations   except   those
corporations  with less  than 2,000  stockholders of  record and  without voting
stock listed on a  national exchange or listed  for quotation with a  registered
national  securities association.  Additional exceptions  allow corporations, in
certain instances, to adopt certificates of incorporation or by-laws that  elect
not to be governed by these provisions. Biocraft has not so elected.
 
     Under  the Companies  Ordinance, transactions  in which  an 'Office Holder'
(defined as  a director,  managing director,  general business  manager,  deputy
managing  director, deputy general business  manager, any other manager directly
subordinate  to   the   managing   director  and   any   person   assuming   the
responsibilities  of  any  of the  foregoing  positions without  regard  to such
person's corporate title) has a direct or indirect 'personal interest,' must  be
approved  by  the company's  Board  of Directors.  In  the case  of  an 'unusual
transaction' (defined by  the Companies  Ordinance as one  which is  not in  the
ordinary   course  of  business,  is  not  on  market  terms  or  is  likely  to
substantially affect the profitability, property or obligations of the company),
such transaction must be approved by the company's audit committee and its Board
of Directors  and, under  certain circumstances,  its shareholders  (e.g., if  a
majority  of the members of the audit committee or the Board of Directors have a
'personal interest' in the transaction). In addition, any transactions in  which
interested  directors holding, in the aggregate,  25% or more of the outstanding
share capital, and constituting  a majority of the  Board or involving  officers
holding  25% or more of  the share capital, must  be authorized by a shareholder
resolution approved by  a majority of  the shareholders, which  must include  at
least one-third of the disinterested shareholders.
 
                                       65
 
<PAGE>
 
<PAGE>
LIMITATION ON DIRECTORS' LIABILITY; INDEMNIFICATION OF OFFICERS AND DIRECTORS
 
     Delaware  law  allows  a corporation  to  limit or  eliminate  the personal
liability of  directors to  the corporation  and its  stockholders for  monetary
damages for breaches of a director's fiduciary duty as a director. However, such
a  limitation does not affect the liability of  a director (i) for any breach of
the director's duty of loyalty to the corporation or its stockholders, (ii)  for
acts or omissions not in good faith or which involve intentional misconduct or a
knowing violation of law, (iii) for intentional or negligent payment of unlawful
dividends  or  stock redemptions  or  (iv) for  any  transaction from  which the
director derived an improper personal benefit. Additionally, the corporation may
not limit or eliminate  liability for acts or  omissions occurring prior to  the
effective date of such a provision in the certificate of incorporation. The DGCL
permits  the indemnification of and the  entering into of insurance contracts to
provide  coverage  of  officers  and  directors.  The  Biocraft  Certificate  of
Incorporation limits the liability of Biocraft's directors to the fullest extent
permitted by Delaware law and the By-laws provide for indemnification of and the
entering  into  insurance contracts  which would  provide coverage  of officers,
directors, employees and other agents for attorneys' fees and other expenses  as
well  as judgments or  amounts paid in  settlement of civil  lawsuits, actual or
threatened.
 
     The Companies  Ordinance  permits  a  company  to  amend  its  articles  of
association  to  provide  that (i)  a  company  may obtain  an  insurance policy
providing insurance  to  an Office  Holder  (as  defined above)  in  respect  of
liabilities incurred by him as a result of the breach of his duty of care to the
company  or to  another person,  or as  a result  of the  breach of  his duty of
loyalty to  the company  to the  extent  that he  acted in  good faith  and  had
reasonable  cause to believe  that the act  would not prejudice  the company, as
well as for  monetary liabilities  to a  third party  charged against  him as  a
result of an act or omission that he committed in connection with his serving as
an Office Holder of a company; and (ii) a company may indemnify an Office Holder
in connection with his activities as an Office Holder, for monetary liability to
a  third  party  incurred pursuant  to  a  judgment, including  a  settlement or
arbitration decision approved by a court,  as well as for reasonable  litigation
expenses,  including attorneys' fees, incurred in  an action brought against him
by, or on behalf of, the company or others, or as a result of a criminal  charge
of  which he  was acquitted. A  company may  not indemnify an  Office Holder nor
enter into an insurance contract which  would provide coverage for any  monetary
liability  incurred as a  result of the following:  (a) a breach  of the duty of
loyalty, except for a breach  of such duty to the  company while acting in  good
faith  and having reasonable cause  to assume that such  act would not prejudice
the interests  of the  company; (b)  a willful  breach of  the duty  of care  or
reckless  disregard for the circumstances or the consequences of a breach of the
duty of care; (c) an act done  with the intent to unlawfully realize a  personal
gain;  or  (d)  a  fine or  bail  imposed  for an  offense.  Teva's  Articles of
Association provide for the insurance and indemnification as described above and
Teva carries the said insurance and has entered into indemnification agreements.
 
LOANS TO DIRECTORS AND OFFICERS
 
     Under Delaware  law,  a  corporation  may  make  loans  to,  guarantee  the
obligations  of or otherwise assist its officers or other employees and those of
its subsidiaries,  including any  officer or  employee who  is a  director of  a
corporation or any of its subsidiaries, when such action, in the judgment of the
corporation's directors, may reasonably be expected to benefit the corporation.
 
     Under  the  Companies Ordinance,  a  company may  contract  as to  terms of
employment (which may  include the  granting of  loans) with  its directors  and
officers, provided that such transactions are approved by the company's board of
directors  (in  the case  of  officers) and  by  its audit  committee,  board of
directors and  shareholders  (in the  case  of directors).  In  the case  of  an
officer,  the approval of the shareholders is also required if a majority of the
board of directors has an interest in the transaction. If the transaction is  an
'unusual  transaction', the procedures  outlined in '  -- Business Combinations'
set forth above must be followed.
 
SPECIAL MEETINGS
 
     Under Delaware law, special meetings of  stockholders may be called by  the
board  of directors and by  such other person or persons  authorized to do so by
the corporation's certificate of incorporation or
 
                                       66
 
<PAGE>
 
<PAGE>
by-laws. Under Delaware law, if an annual meeting is not held within 30 days  of
the date designated for such a meeting, or is not held for a period of 13 months
after  the last  annual meeting,  the Delaware  Court of  Chancery may summarily
order a meeting to be held upon the application of any stockholder or  director.
In  Delaware, the  number of  shares represented  at such  meeting constitutes a
quorum without regard to other provisions of law.
 
     The Biocraft Bylaws provide  that special meetings  of stockholders may  be
called by the Chairman of the Biocraft Board or by the Biocraft Board.
 
     Under  the Companies  Ordinance (and  notwithstanding any  provision to the
contrary in  a  company's articles  of  association), an  extraordinary  general
meeting of shareholders must be called by the board of directors upon request by
a  minimum of  two shareholders  (unless the  articles of  association specify a
different minimum) holding  not less than  one-tenth of the  paid-up capital  of
Teva carrying voting rights at general meetings. An ordinary resolution requires
seven  days notice (unless  otherwise specified by  the articles of association)
and a special resolution requires 21 days notice.
 
WARRANTS OR OPTIONS
 
     Subject to  any restrictions  in the  Certificate of  Incorporation,  under
Delaware  law, rights or options to purchase shares of any class of stock may be
authorized by a corporation's board  of directors. However, various other  legal
requirements  would generally make stockholder approval of stock option plans or
warrants desirable.
 
     Under the Teva  Articles of Association,  the Teva Board  has the power  to
give  to any person the option to acquire from Teva any shares, either at par or
at premium,  or, subject  to the  provisions of  the Companies  Ordinance, at  a
discount,  during such  time and  for such consideration  as the  Teva Board may
think fit. Certain options, such as to  directors, must be approved by the  Teva
Board and shareholders.
 
STOCKHOLDER SUITS
 
     Under  Delaware law, a stockholder may institute a lawsuit on behalf of the
corporation. An individual stockholder may also commence a class action suit  on
behalf   of  himself  and  other   similarly  situated  stockholders  where  the
requirements for maintaining a class action under Delaware law have been met.
 
     Under Israeli law, a shareholder may  institute a lawsuit on behalf of  the
corporation where the requirements for doing so have been met. A stockholder may
also  commence a  class action  suit on  behalf of  himself and  other similarly
situated stockholders  where the  requirements for  maintaining a  class  action
under Israeli law have been met.
 
REGISTRATION OF SHARES IN NAME OF PLEDGEE
 
     Under  Delaware law, a stockholder who  has transferred shares to a pledgee
and registered such transfer  on the books of  the corporation, is  nevertheless
entitled to vote such shares unless such stockholder has expressly empowered the
pledgee to vote such shares.
 
     Under  the  Companies  Ordinance,  an  Israeli  company  is  instructed  to
recognize the person whose  name appears in  the share registry  of Teva as  the
person  entitled to  vote such  shares. Thus,  any stockholder  of Biocraft with
stock presently registered  in the name  of a pledgee  of such stockholder  will
lose the right to vote such stock being replaced with Teva Ordinary Shares.
 
INSPECTION OF CORPORATE BOOKS AND RECORDS; SHAREHOLDER LISTS
 
     Under the DGCL, a stockholder of a corporation has the right to inspect the
books and records of the corporation, either in person or through an attorney or
other  agent,  and to  make  copies or  extracts  therefrom, provided  that such
stockholder has  a  'proper purpose'  for  making such  inspections.  A  'proper
purpose'  is  defined to  mean  a purpose  reasonably  related to  such person's
interest in the corporation  as a stockholder. In  addition, under the DGCL  any
stockholder for any purpose germane to
 
                                       67
 
<PAGE>
 
<PAGE>
a  meeting may examine, during ordinary business hours, for a period of ten (10)
days prior to such meeting the complete list of stockholders entitled to vote at
such meeting,  arranged  in alphabetical  order,  showing the  address  of  each
stockholder and the number of shares registered in the name of each stockholder.
 
     Neither  the  Companies  Ordinance  nor the  Teva  Articles  of Association
confers any right  upon a  shareholder to  review corporate  books and  records.
However,  the Companies Ordinance confers the right upon shareholders to inspect
Teva's register  of  shareholders as  well  as  the minutes  of  Teva's  general
meetings.
 
              SECURITY OWNERSHIP OF DIRECTORS, EXECUTIVE OFFICERS
               AND OWNERS OF 5% OR MORE OF BIOCRAFT COMMON STOCK
 
     The following table sets forth, as of the Record Date, the number of shares
of  Biocraft Common Stock beneficially owned by each director, executive officer
and 5% or more stockholder named below.
 
<TABLE>
<CAPTION>
                                                                                                   PERCENTAGE OF CLASS
                                                                            NUMBER OF SHARES       (* DESIGNATES LESS
                 NAME AND ADDRESS OF BENEFICIAL OWNER                     BENEFICIALLY OWNED(A)        THAN 1%)(B)
- -----------------------------------------------------------------------   ---------------------    -------------------
 
<S>                                                                       <C>                      <C>
Directors
     Harold Snyder.....................................................         3,780,184                  26.6%
     Beatrice Snyder...................................................         3,780,186                  26.6
     Beryl L. Snyder...................................................         1,206,159(c)                8.5
     Brian S. Snyder...................................................         1,187,450(c)                8.4
     Jay T. Snyder.....................................................         1,184,150(c)                8.3
     Gerald Klein......................................................             1,000                    *
     James J. Rahal, Jr., M.D..........................................             5,000                    *
     Madelon DeVoe Talley..............................................             5,000                    *
     Marvin M. Thalenberg, M.D.........................................             1,500                    *
     G. Harold Welch, Jr...............................................             5,355                    *
 
Executive Officers(d)
     Melvin Kaufman....................................................            10,000                    *
     Harmon Aronson....................................................            14,150                    *
     All directors and executive officers as a group (consisting of
       eighteen persons all of whom own Biocraft Common Stock).........         9,220,434                  64.5%
</TABLE>
 
- ------------
 
 (a) Includes shares of Biocraft Common Stock which directors and officers  have
     currently exercisable rights to acquire through the exercise of options, in
     the  amount of 13,350  shares for Beryl  L. Snyder, 12,450  shares each for
     Brian S. Snyder and Jay T. Snyder, 1,000 shares for Mr. Klein, 5,000 shares
     each for Dr. Rahal and Ms.  Talley, 1,000 shares for Dr. Thalenberg,  5,000
     shares  for Mr. Welch, 10,000 shares for Mr. Kaufman, 14,150 shares for Mr.
     Aronson and 115,550 shares  for all directors and  executive officers as  a
     group.
 
 (b) The  number of  shares subject  to options described  in note  (a) for each
     individual were deemed to  be outstanding for  purposes of calculating  the
     percentage  owned by  such individual  and by  all directors  and executive
     officers as a group.
 
 (c) Includes 1,000,000 shares of Common Stock held by trusts created by  Harold
     Snyder and Beatrice Snyder and as to which Beryl L. Snyder, Brian S. Snyder
     and  Jay T. Snyder, as trustees  thereof, have joint dispositive and voting
     control.
 
 (d) Together with Harold  Snyder, Beatrice  Snyder, Beryl L.  Snyder, Brian  S.
     Snyder and Jay T. Snyder, the most highly compensated executive officers.
 
                                       68
 
<PAGE>
 
<PAGE>
                                    EXPERTS
 
     The   consolidated   financial   statements  and   schedules   included  or
incorporated by reference  in Teva's  Annual Report on  Form 20-F  for the  year
ended  December  31, 1995,  which are  incorporated by  reference in  this Proxy
Statement/Prospectus, have  been audited  by  Kesselman &  Kesselman,  Certified
Public  Accountants, Tel Aviv, Israel, as indicated in their report with respect
thereto and are incorporated herein in reliance upon the authority of that  firm
as  experts in accounting and auditing. The financial statements of consolidated
subsidiaries whose assets at December 31, 1995 and 1994 constitute 26% and  16%,
respectively,  of total consolidated assets as of such dates and whose sales for
the years ended December 31,  1995, 1994 and 1993  constitute 20%, 17% and  26%,
respectively,  of total consolidated sales for those years have been examined by
other certified accountants whose  reports have been  included in Teva's  Annual
Report  on Form 20-F for the year ended December 31, 1995, which is incorporated
by reference into this Proxy Statement/Prospectus.
 
     The consolidated financial statements  of Biocraft appearing in  Biocraft's
Annual  Report (Form 10-K as amended by  Form 10-K/A-1) for the year ended March
31, 1995 have been audited  by Ernst & Young  LLP, independent auditors, as  set
forth  in  their  report thereon  included  therein and  incorporated  herein by
reference. Such consolidated financial statements are incorporated in this Proxy
Statement/Prospectus by reference in  reliance upon such  report given upon  the
authority of such firm as experts in accounting and auditing.
 
                                 LEGAL MATTERS
 
     The  validity of the ADRs representing the  Teva ADSs to be issued pursuant
to this Proxy Statement/Prospectus and certain  U.S. tax matters will be  passed
upon  for Teva by Willkie Farr &  Gallagher, United States counsel for Teva, and
the validity of the  Teva Ordinary Shares  to be issued  pursuant to this  Proxy
Statement/Prospectus  will be passed upon for Teva by S. Horowitz & Co., Israeli
counsel for Teva. A partner of Willkie Farr & Gallagher beneficially owns  1,200
Teva ADSs representing 12,000 Ordinary Shares.
 
     Certain U.S. tax matters will be passed upon for Biocraft by Proskauer Rose
Goetz & Mendelsohn LLP, counsel for Biocraft.
 
                                       69


<PAGE>
 
<PAGE>
                                                                         ANNEX I
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
                          AGREEMENT AND PLAN OF MERGER
                                  BY AND AMONG
                    TEVA PHARMACEUTICAL INDUSTRIES LIMITED,
                            GENCO MERGER CORPORATION
                                      AND
                          BIOCRAFT LABORATORIES, INC.
 
                          DATED AS OF JANUARY 29, 1996
 
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------



<PAGE>
 
<PAGE>
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                                                                                             PAGE
                                                                                                             ----
<S>    <C>                                                                                                   <C>
                                                    ARTICLE I
                                                   THE MERGER
 1.01  The Merger.........................................................................................    A-1
 1.02  Effective Time of Merger...........................................................................    A-1
 1.03  Effects of the Merger..............................................................................    A-1
 1.04  Certificate of Incorporation of the Surviving Corporation..........................................    A-1
 1.05  By-Laws of the Surviving Corporation...............................................................    A-2
 1.06  Directors of the Surviving Corporation.............................................................    A-2
 1.07  Officers of the Surviving Corporation..............................................................    A-2
 
                                                   ARTICLE II
                                              CONVERSION OF SHARES
 2.01  Conversion of Share................................................................................    A-2
 2.02  Surrender of Certificates..........................................................................    A-2
 2.03  Fractional ADSs....................................................................................    A-4
 2.04  Closing............................................................................................    A-4
 2.05  Stock Option Plans.................................................................................    A-4
 2.06  Restricted Stock Purchase Plan.....................................................................    A-5
 
                                                   ARTICLE III
                                         REPRESENTATIONS AND WARRANTIES
 3.01  Representations and Warranties of the Company......................................................    A-5
 3.02  Representations and Warranties of Parent and Sub...................................................   A-16
 
                                                   ARTICLE IV
                                     CONDUCT OF BUSINESS; TRANSACTIONS PRIOR
                                     TO CLOSING DATE; ADDITIONAL AGREEMENTS
 4.01  Conduct of Business of the Company.................................................................   A-20
 4.02  Access to Information Concerning Business and Records..............................................   A-21
 4.03  Confidentiality....................................................................................   A-21
 4.04  Registration Statement/Proxy Statement; Listing on Tel Aviv Stock Exchange.........................   A-21
 4.05  Employee Benefits..................................................................................   A-23
 4.06  Company Stockholder Approval; Recommendation.......................................................   A-23
 4.07  Stock Options......................................................................................   A-23
 4.08  Letters of the Company's Accountants...............................................................   A-23
 4.09  Letters of Parent's Accountants....................................................................   A-24
 4.10  Notices of Certain Events..........................................................................   A-24
 4.11  Tel Aviv Stock Exchange Listing....................................................................   A-24
 4.12  NASDAQ/NMS Admission...............................................................................   A-24
 4.13  HSR Act............................................................................................   A-24
 4.14  Indemnification; Officers' and Directors' Insurance................................................   A-24
 4.15  Best Efforts.......................................................................................   A-25
 4.16  Rule 145...........................................................................................   A-25
 4.17  No Solicitation....................................................................................   A-25
 4.18  Post Merger Restructurings.........................................................................   A-26
 4.19  Voting of Shares Subject to Proxy..................................................................   A-26
 4.20  Parent Shareholder Meeting.........................................................................   A-26
 4.21  Dispositions Contrary to Pooling...................................................................   A-27
 4.22  Dividend Reinvestment Plan.........................................................................   A-27
</TABLE>
 
                                       i
 
<PAGE>
 
<PAGE>
 
<TABLE>
<CAPTION>
                                                                                                             PAGE
                                                                                                             ----
<S>    <C>                                                                                                   <C>
                                                    ARTICLE V
                                         CONDITIONS PRECEDENT TO MERGER
 
 5.01  Conditions Precedent to Obligations of Parent, Sub and the Company.................................   A-27
 5.02  Conditions Precedent to Obligations of Parent and Sub..............................................   A-28
 5.03  Conditions Precedent to Obligation of the Company..................................................   A-29
 
                                                   ARTICLE VI
                                           TERMINATION AND ABANDONMENT
 6.01  Termination........................................................................................   A-30
 6.02  Effect of Termination..............................................................................   A-30
 
                                                   ARTICLE VII
                                                  MISCELLANEOUS
 7.01  Fees and Expenses..................................................................................   A-31
 7.02  Representations, Warranties and Agreements.........................................................   A-31
 7.03  Extension; Waiver..................................................................................   A-31
 7.04  Public Announcements...............................................................................   A-32
 7.05  Notices............................................................................................   A-32
 7.06  Entire Agreement...................................................................................   A-33
 7.07  Binding Effect; Benefit; Assignment................................................................   A-33
 7.08  Amendment and Modification.........................................................................   A-33
 7.09  Further Actions....................................................................................   A-33
 7.10  Headings...........................................................................................   A-33
 7.11  Counterparts.......................................................................................   A-33
 7.12  Applicable Law.....................................................................................   A-33
 7.13  Severability.......................................................................................   A-33
 7.14  'Person' Defined...................................................................................   A-33
 7.15  Submission to Jurisdiction.........................................................................   A-33
</TABLE>
 
SCHEDULES
- -----------
Schedule I   Designated Directors
Schedule II  Designated Officers
 
EXHIBITS (NOT INCLUDED)
- -----------
Exhibit A    Form of Basic Affiliate Agreement
Exhibit A-1  Form of Affiliate Agreement for Harold and Beatrice Snyder
Exhibit B-1  List of Employment Agreement Employees
Exhibit B-2  Form of Employment Agreement
Exhibit C    Form of Opinion of Proskauer Rose Goetz & Mendelsohn LLP
Exhibit D-1  Form of Opinion of Willkie Farr & Gallagher
Exhibit D-2  Form of Opinion of S. Horowitz & Co.
 
                                       ii

<PAGE>
 
<PAGE>
                          AGREEMENT AND PLAN OF MERGER
 
     AGREEMENT   AND  PLAN  OF  MERGER,  dated  as  of  January  29,  1996  (the
'Agreement'), by and among TEVA PHARMACEUTICAL INDUSTRIES LIMITED, a corporation
organized under  the  laws of  the  State  of Israel  ('Parent'),  GENCO  MERGER
CORPORATION,  a Delaware  corporation and  a wholly  owned subsidiary  of Parent
('Sub'),  and  BIOCRAFT   LABORATORIES,  INC.,  a   Delaware  corporation   (the
'Company').
 
     WHEREAS,  the respective Boards of Directors of the Company and Parent have
each determined unanimously that it is in the best interests of their respective
companies and  stockholders that  Parent  acquire the  business of  the  Company
pursuant to the terms and conditions set forth in this Agreement;
 
     WHEREAS, the respective Boards of Directors of Parent, Sub and the Company,
and  Parent acting as the  sole stockholder of Sub,  have approved the merger of
Sub into  the Company  (the 'Merger'),  pursuant and  subject to  the terms  and
conditions  of  this Agreement,  whereby each  issued  and outstanding  share of
common stock, par value $.01 per share, of the Company ('Company Common  Stock')
will  be converted into the right to receive 4.61 Ordinary Shares, par value NIS
0.01 each, of Parent ('Ordinary Shares')  which will trade in the United  States
in  the  form  of American  Depositary  Shares ('ADSs'),  evidenced  by American
Depositary Receipts (the 'ADRs');
 
     WHEREAS, the respective Boards of Directors of the Company and Parent  have
each  determined  unanimously  that the  Merger  is  fair to,  and  in  the best
interests of, their respective companies and stockholders and have approved  the
Merger,  and the Board of Directors of  the Company has recommended the approval
and adoption of this Agreement by the Company's stockholders;
 
     WHEREAS, for United States federal income tax purposes, it is intended that
the Merger  shall qualify  as a  reorganization within  the meaning  of  Section
368(a)(2)(E) of the Internal Revenue Code of 1986, as amended, and the rules and
regulations promulgated thereunder (the 'Code'); and
 
     WHEREAS,  it is intended  that the Merger shall  be recorded for accounting
purposes as  a  pooling of  interests  under United  States  generally  accepted
accounting principles ('US GAAP');
 
     NOW,  THEREFORE,  in  consideration  of  the  premises  and  of  the mutual
representations, warranties,  covenants  and agreements  herein  contained,  the
parties hereto agree as follows:
 
                                   ARTICLE I
                                   THE MERGER
 
     1.01  The Merger. Subject to the terms and conditions of this Agreement, at
the time of the Closing  (as defined in Section  2.04 hereof), a certificate  of
merger  (the 'Certificate of Merger') shall be duly executed and acknowledged by
Sub and the Company in accordance with the Delaware General Corporation Law (the
'DGCL') and shall  be filed  on the  Closing Date  (as defined  in Section  2.04
hereof). The Merger shall become effective upon the filing of the Certificate of
Merger  with the  Secretary of State  of the State  of Delaware or  at such time
thereafter as is provided  in the Certificate of  Merger in accordance with  the
provisions and requirements of the DGCL. The date and time when the Merger shall
become effective is hereinafter referred to as the 'Effective Time.'
 
     1.02  Effective Time of Merger. At the  Effective Time, Sub shall be merged
with and into  the Company  and the separate  corporate existence  of Sub  shall
cease,  and the  Company shall continue  as the surviving  corporation under the
laws of the State  of Delaware under the  name of 'Biocraft Laboratories,  Inc.'
(the 'Surviving Corporation').
 
     1.03  Effects of the Merger. From and  after the Effective Time, the Merger
shall have the effects set forth in Section 259(a) of the DGCL.
 
     1.04 Certificate of Incorporation  of the Surviving Corporation.  Effective
as  of the Effective Time, the Certificate of Incorporation of the Company shall
be amended and restated in its entirety so that upon such amendment it shall  in
all respects be equivalent in its content to the Certificate of Incorporation of
Sub, as in effect immediately prior to the Effective Time, except that Paragraph
1 thereof read as follows:
 
                                      A-1
 
<PAGE>
 
<PAGE>
          'The   name  of  the  corporation   (the  'Corporation')  is  Biocraft
     Laboratories, Inc.'
 
     1.05 By-Laws of the Surviving Corporation. The By-Laws of Sub, as in effect
immediately prior to the Effective Time,  shall be the By-Laws of the  Surviving
Corporation.
 
     1.06  Directors of  the Surviving Corporation.  At the  Effective Time, the
Persons listed on Schedule I hereto shall, subject to the applicable  provisions
of the Certificate of Incorporation and By-Laws of the Surviving Corporation, be
the  directors of  the Surviving  Corporation until  their respective successors
shall be duly elected or appointed and qualified.
 
     1.07 Officers  of the  Surviving Corporation.  At the  Effective Time,  the
Persons listed on Schedule II hereto shall, subject to the applicable provisions
of the Certificate of Incorporation and By-Laws of the Surviving Corporation, be
the  officers  of the  Surviving Corporation  until their  respective successors
shall be duly elected or appointed and qualified.
 
                                   ARTICLE II
                              CONVERSION OF SHARES
 
     2.01 Conversion of Shares. At the  Effective Time, by virtue of the  Merger
and without any action on the part of the holder of any shares of Company Common
Stock or any holder of capital stock of Sub:
 
          (a)  Capital Stock  of Sub.  Each share of  capital stock  of Sub then
     issued and outstanding shall become one fully paid and nonassessable  share
     of common stock, $0.01 par value, of the Surviving Corporation which shares
     shall  be issued to Parent and shall constitute the only outstanding shares
     of capital stock of the Surviving Corporation.
 
          (b) Cancellation of Treasury Stock. All shares of Company Common Stock
     that are  owned by  the Company  as treasury  stock shall  be canceled  and
     retired  and shall cease to  exist and no share  capital of Parent or other
     consideration shall be delivered in exchange therefor.
 
          (c)  Exchange  Ratio  for  Company  Common  Stock.  Each  issued   and
     outstanding share of Company Common Stock (other than shares to be canceled
     in  accordance with Section  2.01(b)) shall be converted  into and shall be
     canceled in exchange  for the right  to receive 4.61  Ordinary Shares  (the
     'Exchange  Ratio') duly  issued and credited  as fully paid  (which will be
     represented  by  ADSs  in  accordance  with  Section  2.02)  (the   'Merger
     Consideration').  If between the  date of this  Agreement and the Effective
     Time the outstanding  Ordinary Shares  of Parent  shall be  changed into  a
     different  number of shares  by reason of  any stock dividend, subdivision,
     reclassification, split-up,  combination or  the like,  the Exchange  Ratio
     shall be appropriately adjusted.
 
          (d) Cancellation of Company Common Stock. All shares of Company Common
     Stock converted into Ordinary Shares pursuant to this Section 2.01 shall no
     longer  be outstanding and shall automatically  be canceled and retired and
     shall cease to  exist, and each  holder of a  certificate representing  any
     such shares shall cease to have any rights with respect thereto, except the
     right  to receive  Ordinary Shares to  be issued  in consideration therefor
     upon the surrender  of such  certificate in accordance  with Section  2.02,
     without interest.
 
          (e)  Allotment of  Ordinary Shares. In  consideration of  the issue to
     Parent by  the Surviving  Corporation  of shares  of  common stock  of  the
     Surviving  Corporation  and the  cancellation of  shares of  Company Common
     Stock, Parent shall allot, in exchange for  the issue to Parent of all  the
     unissued  shares  of common  stock of  the Surviving  Corporation, Ordinary
     Shares to be issued to the Exchange  Agent (as defined in Section 2.02)  on
     behalf  of such Persons  as the Company  shall nominate for  the purpose of
     giving effect to the conversion and exchange referred to in Section 2.01(c)
     of this Agreement.
 
     2.02 Surrender  of Certificates.  (a)  Concurrently with  or prior  to  the
Effective  Time, the parties hereto shall designate  The Bank of New York to act
as  agent  (the  'Exchange  Agent')  for  purposes  of  exchanging  certificates
representing  shares of  Company Common Stock  as provided in  Section 2.01. The
Exchange Agent currently acts as the Depositary for the ADSs (in such  capacity,
the  'Depositary'). Each ADS  represents a unit consisting  of ten (10) Ordinary
Shares. As soon as practicable after the
 
                                      A-2
 
<PAGE>
 
<PAGE>
Effective Time, Parent shall cause the Exchange Agent to mail or make  available
to  each holder  of record  of a  certificate or  certificates which immediately
prior to the  Effective Time  represented outstanding shares  of Company  Common
Stock  whose shares  were converted  into the  right to  receive Ordinary Shares
pursuant to Section 2.01 a notice and letter of transmittal advising such holder
of the effectiveness  of the Merger  and the procedure  for surrendering to  the
Exchange  Agent such certificate or certificates  which immediately prior to the
Effective Time  represented  outstanding  shares  of  Company  Common  Stock  in
exchange for the Merger Consideration deliverable in respect thereof pursuant to
this  Article II.  To the extent  required, the Exchange  Agent will requisition
from the Depositary, from time to time,  such number of ADRs evidencing ADSs  as
are  issuable in respect of shares of Company Common Stock properly delivered to
the Exchange Agent. At the Effective Time, the Surviving Corporation shall issue
to Parent the shares of common stock of the Surviving Corporation referred to in
Section 2.01(a). The Parent  shall, prior to  the Effective Time,  conditionally
allot Ordinary Shares referred to in Sections 2.01(c) and 2.01(e) subject to the
terms and conditions of this Agreement.
 
     (b)  Each holder of shares of Company  Common Stock that has been converted
into a right to receive the Merger Consideration, upon surrender to the Exchange
Agent of a certificate or  certificates representing such Company Common  Stock,
together with a properly completed letter of transmittal covering such shares of
Company  Common Stock, will be entitled  to receive ADRs representing 0.461 ADSs
in respect  of  each  share  of  Company  Common  Stock  surrendered.  Until  so
surrendered, each share of Company Common Stock shall, after the Effective Time,
represent  for all  purposes, only  the right  to receive  ADRs evidencing 0.461
ADSs, each ADS representing ten (10) Ordinary Shares.
 
     (c) If any  ADSs are to  be issued to  a Person other  than the  registered
holder   of  the  Company  Common  Stock   represented  by  the  certificate  or
certificates surrendered with respect thereto, it  shall be a condition to  such
issuance  that the certificate or certificates  so surrendered shall be properly
endorsed or  otherwise  be in  proper  form for  transfer  and that  the  Person
requesting  such issuance shall pay to the  Exchange Agent any transfer or other
taxes required  as  a  result of  such  issuance  to a  Person  other  than  the
registered  holder of such Company Common Stock or establish to the satisfaction
of the Exchange Agent that such tax has been paid or is not payable.
 
     (d) As of  the Effective Time,  there shall be  no further registration  of
transfers  of shares of Company Common Stock  that were outstanding prior to the
Merger. After the  Effective Time, certificates  representing shares of  Company
Common  Stock  presented  to the  Surviving  Corporation for  transfer  shall be
canceled and exchanged  for the  consideration provided for,  and in  accordance
with the procedures set forth, in this Article II.
 
     (e) At the close of business on the Effective Time, the stock ledger of the
Company  with respect to the  issuance of Company Common  Stock shall be closed.
Six months after the Effective Time,  any Ordinary Shares made available to  the
Exchange  Agent pursuant to Section 2.01(e) and  any portion of the Common Stock
Trust (as defined  in Section  2.03) that remains  unclaimed by  the holders  of
shares of Company Common Stock shall be returned to Parent upon demand. Any such
holder  who has not delivered his shares of Company Common Stock to the Exchange
Agent in accordance with Section 2.02  prior to that time shall thereafter  look
only  to Parent and the Surviving Corporation for issuance of ADSs in respect of
shares of Company  Common Stock. Notwithstanding  the foregoing, neither  Parent
nor the Surviving Corporation shall be liable to any holder of shares of Company
Common  Stock  for any  securities  delivered or  any  amount paid  to  a public
official pursuant to  applicable abandoned  property laws.  Any Ordinary  Shares
remaining  unclaimed by  holders of shares  of Company Common  Stock three years
after the Effective Time (or such earlier date immediately prior to such time as
such  securities  would  otherwise  escheat   to  or  become  property  of   any
governmental entity or as is otherwise provided by applicable law) shall, to the
extent  permitted by applicable law, be free and clear of any claims or interest
of any Person previously entitled thereto.
 
     (f)  No  dividends,  interest  or  other  distributions  with  respect   to
securities  of  Parent or  the Surviving  Corporation  issuable with  respect to
Company  Common  Stock  shall  be  paid  to  the  holder  of  any  unsurrendered
certificates  representing  Company  Common Stock  until  such  certificates are
surrendered as provided  in this Section.  Upon such surrender,  there shall  be
paid, without interest, to the Person in
 
                                      A-3
 
<PAGE>
 
<PAGE>
whose  name the ADSs representing such  securities are registered, all dividends
and other  distributions  payable  in  respect of  such  securities  on  a  date
subsequent to, and in respect of a record date after, the Effective Time.
 
     2.03  Fractional ADSs. No fraction of an ADS will be issued and no dividend
or other distribution, stock split or  interest with respect to Ordinary  Shares
shall  relate  to any  fractional ADS,  and such  fractional interest  shall not
entitle the owner  thereof to  vote or  to any rights  as a  security holder  of
Parent.  In  lieu of  any such  fractional  security, each  holder of  shares of
Company Common Stock otherwise entitled to a fraction of an ADS will be entitled
to receive at  the time such  holder receives ADRs  pursuant to Section  2.02(b)
hereof  and in  accordance with  the provisions  of this  Section 2.03  from the
Exchange Agent a cash payment representing such holder's proportionate  interest
in  the net proceeds from the  sale by the Exchange Agent  on behalf of all such
holders of  the aggregate  of the  fractions of  ADSs which  would otherwise  be
issued  (the 'Excess ADSs'). The  sale of the Excess  ADSs by the Exchange Agent
shall be executed on  the National Association  of Securities Dealers  Automated
Quotations  National  Market System  ('NASDAQ/NMS') through  one or  more market
makers in  the  ADSs  and  shall  be  executed  in  round  lots  to  the  extent
practicable.  Until the net proceeds of such sale or sales have been distributed
to the holders of shares of the  Company Common Stock, the Exchange Agent  will,
subject  to Section  2.02(e), hold  such proceeds  in trust  for the  holders of
shares of Company Common Stock (the 'Common Stock Trust'). The Parent shall  pay
all  commissions,  transfer  taxes and  other  out-of-pocket  transaction costs,
including the  expenses and  compensation,  of the  Exchange Agent  incurred  in
connection with such sale of the Excess ADSs. The Exchange Agent shall determine
the  portion of the Common Stock Trust to which each holder of shares of Company
Common Stock  shall  be entitled,  if  any, by  multiplying  the amount  of  the
aggregate  net  proceeds comprising  the Common  Stock Trust  by a  fraction the
numerator of which is the  amount of the fractional  ADS interest to which  such
holder  of shares  of Company  Common Stock is  entitled and  the denominator of
which is the aggregate amount of  fractional ADS interests to which all  holders
of shares of Company Common Stock are entitled. As soon as practicable after the
determination  of the amount of cash, if any, to be paid to holders of shares of
Company Common Stock in lieu of any fractional ADS interests, the Exchange Agent
shall make  available such  amounts to  such holders  of shares  of the  Company
Common Stock without interest.
 
     2.04 Closing. The closing of the Merger (the 'Closing') shall take place at
the  offices of  Willkie Farr  & Gallagher, One  Citicorp Center,  153 East 53rd
Street, New York, New York 10022, as  soon as practicable after the last of  the
conditions  set forth  in Article  V hereof is  fulfilled or  waived (subject to
applicable law) but in no event later than the fifth business day thereafter, or
at such other time and  place and on such other  date as Parent and the  Company
shall mutually agree (the 'Closing Date').
 
     2.05  Stock Option Plans. Prior  to the Effective Time,  but subject to the
consummation of  the Merger,  the Board  of  Directors of  the Company  and  the
committee  appointed by the Board to administer the Company's stock option plans
shall take all action reasonably necessary  or appropriate to (i) terminate  the
Company's   Incentive  Stock  Option  Plan  and  all  options  then  outstanding
thereunder, (ii) terminate the Company's 1987 Directors' Stock Option Plan,  and
all  options outstanding thereunder, each such termination to be effective as of
the Effective  Time, (iii)  terminate  all other  Company plans,  or  agreements
providing  for the  grant of  stock options or  other rights  to acquire Company
Common Stock to any  person (the plans  identified in clauses  (i) and (ii)  and
such  other plans  or agreements  being collectively  referred to  herein as the
'Stock Option Plans'), (iv) give written notice of such action to the holder  of
each  option outstanding under the  Stock Option Plans, (v)  offer the holder of
each option  outstanding under  the Stock  Option Plans  the right,  by  written
notice  delivered  to  the Company  at  least  ten business  days  prior  to the
Effective Time, to exercise all such options, whether or not then exercisable by
the terms of the applicable option agreements, and (vi) provide that each option
outstanding under the Stock Option Plans as to which no such notice of  exercise
shall  have been so delivered (other than  options held by executive officers or
directors subject to Section 16 of  the Exchange Act) shall represent the  right
to receive promptly after the Effective Time, as to each share of Company Common
Stock covered thereby (without regard to any then applicable restrictions on the
exercise  of  such options),  the number  of  ADSs of  Parent determined  by (i)
multiplying the  Exchange Ratio  by  the fair  market value  of  an ADS  on  the
Effective Date, (ii) subtracting from the product of
 
                                      A-4
 
<PAGE>
 
<PAGE>
such  multiplication the  sum of  the applicable  per share  exercise price plus
applicable per share withholding for taxes (which will be appropriately remitted
to the applicable tax authority on  behalf of such optionee) and (iii)  dividing
the  amount obtained in  clause (ii) by the  fair market value of  an ADS on the
Effective Date. For purposes of this Section  2.05, the fair market value of  an
ADS  on the Effective Date shall mean the  average of the last sale prices of an
ADS on the NASDAQ/NMS on  each of the ten trading  days ending two trading  days
prior to the Effective Date.
 
     2.06  Restricted  Stock Purchase  Plan. Prior  to  the Effective  Time, but
subject to the consummation of the Merger, the Board of Directors of the Company
and the committee appointed by the Board to administer the Company's  Restricted
Stock  Purchase Plan shall cause such Plan to  be amended to (a) provide that no
further restricted stock grants be made  after the Effective Time of the  Merger
and  (b) provide that the  terms and conditions of such  Plan shall apply to the
ADSs and Ordinary  Shares issued upon  the Merger to  the holders of  restricted
stock  under such  Plan, and  such holders shall  thereafter hold  such ADSs and
Ordinary Shares subject  to the  terms and  conditions of  such Plan,  including
without  limitation any requirement for the legending of certificates evidencing
such securities.
 
                                  ARTICLE III
                         REPRESENTATIONS AND WARRANTIES
 
     3.01 Representations  and Warranties  of the  Company. The  Company  hereby
represents and warrants to Parent and Sub as follows:
 
          (a) Due Organization, Good Standing and Power. Each of the Company and
     the Subsidiaries (as that term is defined in Section 3.01(c)(ii) hereof) is
     a  corporation duly organized, validly existing  and in good standing under
     the laws of the jurisdiction of its incorporation and each such corporation
     has all  requisite  power and  authority  to  own, lease  and  operate  its
     properties and to carry on its business as now being conducted. Each of the
     Company  and the Subsidiaries is duly  qualified or licensed to do business
     and is in good standing in  each jurisdiction in which the property  owned,
     leased  or operated  by it or  the nature  of the business  conducted by it
     makes such qualification necessary, except in such jurisdictions where  the
     failure  to be so qualified or licensed and in good standing would not have
     a material adverse effect on the business, properties, assets, liabilities,
     operations, results  of operations  or condition  (financial or  otherwise)
     (the 'Condition') of the Company and the Subsidiaries taken as a whole.
 
          (b)  Authorization  and Validity  of Agreement.  The Company  has full
     corporate power and  authority to  execute and deliver  this Agreement,  to
     perform  its obligations hereunder and,  subject to obtaining any necessary
     stockholder  approval  of  the  Merger,  to  consummate  the   transactions
     contemplated  hereby.  The  execution,  delivery  and  performance  of this
     Agreement by the Company,  and the consummation by  it of the  transactions
     contemplated  hereby, have been duly  authorized by all necessary corporate
     action on the part of the Company, subject to the approval of the Merger by
     the Company's  stockholders  in accordance  with  the DGCL.  The  Board  of
     Directors  of  the  Company  has  taken  all  action  necessary  to  render
     inapplicable, as it relates to Parent, the provisions of Section 203 of the
     DGCL. No other corporate action on the part of the Company is necessary  to
     authorize  the execution, delivery and performance of this Agreement by the
     Company and the consummation of the transactions contemplated hereby (other
     than the approval of the Merger by the  holders of at least 66 2/3% of  the
     Company Common Stock). To the Company's knowledge, other than the Insurance
     Holding Company Systems law of the State of Hawaii, no other state takeover
     statute  or similar statute  or regulation applies or  purports to apply to
     the Merger, this Agreement and  the transactions contemplated hereby.  This
     Agreement  has been  duly executed  and delivered by  the Company  and is a
     valid and binding obligation of the Company enforceable against the Company
     in accordance with its terms, except to the extent that its  enforceability
     may  be  subject  to  applicable  bankruptcy,  insolvency,  reorganization,
     moratorium and similar laws affecting the enforcement of creditors'  rights
     generally and by general equitable principles.
 
          (c)  Capitalization. (i) The  authorized capital stock  of the Company
     consists of 30,000,000 shares of Company Common Stock, $0.01 par value, and
     2,000,000 shares of preferred stock, $1.00
 
                                      A-5
 
<PAGE>
 
<PAGE>
     par value (the 'Preferred  Stock'). As of January  5, 1996, (1)  14,182,691
     shares  of Company  Common Stock were  issued and  outstanding, (2) 169,200
     shares of Company Common Stock were reserved for issuance upon the exercise
     of outstanding options granted under stock  option plans, (3) no shares  of
     Preferred  Stock  were issued  and outstanding,  and  (4) 59,331  shares of
     Company Common Stock were  held in the Company's  treasury. All issued  and
     outstanding  shares of Company  Common Stock have  been duly authorized and
     validly issued  and are  fully paid  and nonassessable,  and none  of  such
     shares are subject to, nor were they issued in violation of, any preemptive
     rights.  Except  as  set  forth  in this  Section  3.01(c)  or  on Schedule
     3.01(c)(i) delivered to Parent by the Company, and except for changes since
     January 5, 1996 resulting from the  exercise of employee or director  stock
     options  outstanding on such date, or  the issuance or repurchase of shares
     of Common Stock pursuant to the Company's Stockholder Dividend Reinvestment
     and Stock Purchase Plan, (i)  there are no shares  of capital stock of  the
     Company  authorized, issued or outstanding and (ii) there are not as of the
     date hereof, and at the Effective  Time there will not be, any  outstanding
     options,   warrants,  rights,  subscriptions,   claims  of  any  character,
     agreements, obligations, convertible  or exchangeable  securities or  other
     commitments,  contingent or otherwise, relating  to Company Common Stock or
     any other shares  of capital stock  of the Company,  pursuant to which  the
     Company  is  or may  become  obligated to  issue  or purchase  or otherwise
     acquire shares of  Company Common Stock,  any other shares  of its  capital
     stock  or any securities convertible  into, exchangeable for, or evidencing
     the right to subscribe for, any shares of the capital stock of the Company.
 
          (ii) Schedule 3.01(c)(ii) delivered to Parent by the Company lists all
     of the Company's  subsidiaries (except  for subsidiaries  with no  material
     assets  or liabilities)  (such subsidiaries listed  on Schedule 3.01(c)(ii)
     being herein referred  to as the  'Subsidiaries'). Except as  set forth  on
     Schedule 3.01(c)(ii), all issued and outstanding shares of capital stock of
     the   Subsidiaries   have  been   validly  issued,   are  fully   paid  and
     nonassessable, are not subject  to, nor were they  issued in violation  of,
     any  preemptive rights, and are owned, of record and beneficially, directly
     or indirectly, by the Company, free  and clear of all liens,  encumbrances,
     options  or claims  whatsoever. No  shares of capital  stock of  any of the
     Subsidiaries are  reserved for  issuance and  there are  no outstanding  or
     authorized   options,  warrants,  rights,   subscriptions,  claims  of  any
     character, agreements, obligations, convertible or exchangeable securities,
     or other  commitments, contingent  or otherwise,  relating to  the  capital
     stock of any Subsidiary, pursuant to which such Subsidiary is or may become
     obligated  to issue or purchase or  otherwise acquire any shares of capital
     stock of such Subsidiary or  any securities convertible into,  exchangeable
     for,  or evidencing the right to subscribe for, any shares of capital stock
     of such Subsidiary. Except as set forth in Schedule 3.01(c)(ii), there  are
     no  restrictions of any kind which prevent  the payment of dividends by any
     of the  Subsidiaries. Except  (A) for  the Subsidiaries,  (B) as  otherwise
     listed  on Schedule 3.01(c)(ii), (C)  ordinary course portfolio investments
     in marketable securities and cash  equivalents and (D) subsidiaries of  the
     Company  with no material assets or  liabilities, the Company does not own,
     directly or indirectly, any capital stock  or other equity interest in  any
     Person  (as defined in Section 7.14) or  have any direct or indirect equity
     or ownership interest in any Person and neither the Company nor any of  the
     Subsidiaries  is  subject  to any  obligation  or requirement  to  make any
     material loan, capital contribution,  investment or similar expenditure  to
     or  in any Person, except for  loans, capital contributions, investments or
     similar expenditures  by the  Company or  any of  the Subsidiaries  to  any
     Subsidiary of the Company or to the Company.
 
          (d)  Consents  and Approvals;  No  Violations. Assuming  that  (i) the
     filings required under the Hart-Scott-Rodino Antitrust Improvements Act  of
     1976,  as  amended  (the  'HSR  Act'),  are  made  and  the  waiting period
     thereunder has been  terminated or has  expired; (ii) the  filing with  the
     Securities and Exchange Commission (the 'Commission') of a definitive proxy
     statement  (the 'Proxy Statement') relating to the meeting of the Company's
     stockholders to be held  in connection with the  Merger is made; (iii)  the
     Registration  Statement of Parent  to be filed with  the Commission on Form
     F-4 in  connection with  the issuance  of Ordinary  Shares (which  will  be
     represented  by  the  ADSs)  (the  'Registration  Statement')  is  declared
     effective and a Registration Statement  on Form F-6 (the 'F-6  Registration
     Statement')  is declared effective;  (iv) the filing  of the Certificate of
     Merger and other appropriate merger documents,  if any, as required by  the
     laws of the State of
 
                                      A-6
 
<PAGE>
 
<PAGE>
     Delaware,  is made; (v) approval of the Merger by 66 2/3% of the holders of
     Company Common Stock is obtained; (vi) approval of the insurance regulatory
     authorities in the  State of Hawaii  is obtained; and  (vii) for each  real
     property  owned or operated by the Company or any Subsidiary located in the
     State of New Jersey, either a Letter of Non-Applicability, approval by  the
     New  Jersey Department of Environmental Protection  and Energy ('DEP') of a
     Negative Declaration submitted by the  Company, a no further action  letter
     from  DEP, the  filing by  the Company of  a De  Minimis Quantity Exemption
     Affidavit, a letter of authorization for the transfer of ownership from DEP
     or approval by DEP of a Remediation Agreement (any of the foregoing,  'ISRA
     Clearance') is obtained pursuant to the New Jersey Industrial Site Recovery
     Act,  N.J.S.A.  13:1K-6  et seq.  and  the regulations  of  DEP promulgated
     thereunder (collectively,  'ISRA'),  the  execution and  delivery  of  this
     Agreement  by  the  Company and  the  consummation  by the  Company  of the
     transactions contemplated hereby will not: (1) violate any provision of the
     Certificate of Incorporation, as amended, or By-Laws of the Company or  any
     of  the  Subsidiaries; (2)  to the  knowledge of  the Company,  violate any
     statute, ordinance, rule, regulation,  order or decree of  any court or  of
     any  governmental or regulatory body, agency or authority applicable to the
     Company or any  of the  Subsidiaries or by  which any  of their  respective
     properties  or  assets  may  be bound,  including  without  limitation, any
     consent decrees, court orders or judgments; (3) require any filing with, or
     permit, consent  or  approval  of, or  the  giving  of any  notice  to  any
     governmental  or regulatory body, agency or authority, domestic or foreign,
     including without  limitation, any  such  bodies, agencies  or  authorities
     regulating  the  pharmaceutical business  of  the Company  (a 'Governmental
     Entity'); or (4) except  as set forth on  Schedule 3.01(d)(4) delivered  to
     Parent  by the Company, result in a  violation or breach of, conflict with,
     constitute (with or without due notice or lapse of time or both) a  default
     (or  give  rise  to  any right  of  termination,  cancellation,  payment or
     acceleration) under,  or  result in  the  creation of  any  lien,  security
     interest, charge or encumbrance upon any of the properties or assets of the
     Company  or any of the Subsidiaries under,  any of the terms, conditions or
     provisions of  any note,  bond,  mortgage, indenture,  license,  franchise,
     permit,  agreement, lease  or other instrument  or obligation  to which the
     Company or any of  the Subsidiaries is a  party, or by which  it or any  of
     their  respective properties  or assets  may be  bound, excluding  from the
     foregoing clauses (2),  (3) and (4)  filings, permits, consents,  approvals
     and  notices  the absence  of which,  and violations,  breaches, conflicts,
     defaults and  liens which,  in the  aggregate, would  not have  a  material
     adverse  effect on the Condition of  the Company and the Subsidiaries taken
     as a whole.
 
          (e) Company Reports and Financial Statements; Accounting Records.  (i)
     Since  March  31,  1991,  the  Company has  filed  all  forms,  reports and
     documents with the Commission  required to be filed  by it pursuant to  the
     U.S.  federal  securities laws  and the  rules and  regulations promulgated
     thereunder, and all forms, reports and documents filed with the  Commission
     have  complied in all material respects with all applicable requirements of
     the U.S. federal securities laws  and the Commission rules and  regulations
     promulgated thereunder. The Company has heretofore delivered to Parent true
     and  complete  copies of  all forms,  reports, registration  statements and
     other filings filed by the Company with the Commission since March 31, 1991
     (such forms, reports, registration  statements and other filings,  together
     with  any amendments thereto, are sometimes collectively referred to as the
     'Company Commission Filings').  As of their  respective dates, the  Company
     Commission  Filings did not contain any untrue statement of a material fact
     or omit to state a material fact required to be stated therein or necessary
     to make the statements therein, in  light of the circumstances under  which
     they were made, not misleading.
 
          (ii)  The audited consolidated financial  statements and the unaudited
     interim financial  statements  of  the  Company  included  in  the  Company
     Commission  Filings  comply  as  to  form  in  all  material  respects with
     applicable accounting requirements  and with the  rules and regulations  of
     the  Commission with respect  thereto, were prepared  in accordance with US
     GAAP (as in effect from time to time) applied on a consistent basis (except
     as may  be indicated  therein or  in the  notes or  schedules thereto)  and
     fairly present in all material respects the consolidated financial position
     of  the Company and  its consolidated subsidiaries as  of the dates thereof
     and the results of their operations and changes in cash flows, as the  case
     may  be, for the periods  then ended subject, in  the case of the unaudited
     interim financial  statements,  to  normal  and  recurring  year-end  audit
     adjustments,  any  other adjustments  described therein  and the  fact that
     certain information and
 
                                      A-7
 
<PAGE>
 
<PAGE>
     notes have  been condensed  or omitted  in accordance  with the  Securities
     Exchange  Act  of  1934 (the  'Exchange  Act'), and  the  rules promulgated
     thereunder.
 
          (iii) The Company and the Subsidiaries keep proper accounting  records
     in   which  all   material  assets   and  liabilities,   and  all  material
     transactions,  of  the  Company  and  its  subsidiaries  are  recorded   in
     conformity  with applicable  accounting principles. Except  as described on
     Schedule 3.01(e)(iii) delivered by  the Company to Parent,  no part of  the
     Company's  or  any Subsidiary's  accounting  system or  records,  or access
     thereto, is under the  control of a  Person who is not  an employee of  the
     Company or such Subsidiary.
 
          (f)  Absence  of  Certain  Changes.  Except  as  disclosed  in Company
     Commission Filings filed prior to the  date hereof, or on Schedule  3.01(f)
     delivered  to Parent by the Company, since September 30, 1995 (i) there has
     not been any material  adverse change in the  Condition of the Company  and
     the  Subsidiaries taken as a whole; (ii)  the businesses of the Company and
     the Subsidiaries have been conducted in  all material respects only in  the
     ordinary  course; (iii)  the Company and  the Subsidiaries  have not, other
     than in the ordinary course of business, increased the compensation of  any
     officer  or  granted  any  general salary  or  benefits  increase  to their
     employees; and (iv)  neither the Company  nor any of  the Subsidiaries  has
     taken  any action referred to in Section 4.01 hereof except as permitted or
     required thereby.
 
          (g) Regulatory  Compliance.  (i)  Schedule 3.01(g)  delivered  by  the
     Company to Parent sets forth a list of each product manufactured, marketed,
     sold  or licensed  by the  Company or  any Subsidiary  (the 'Pharmaceutical
     Products') as of January 1, 1996.
 
          (ii) Schedule 3.01(g) delivered by the Company to Parent sets forth  a
     list   of  all  (A)  Pharmaceutical  Products  which  have  been  recalled,
     withdrawn, suspended or discontinued  by the Company  in the United  States
     and outside the United States (whether voluntarily or otherwise) during the
     period  commencing April  1, 1991  and ending  on the  date hereof  and (B)
     proceedings in the United States and outside of the United States of  which
     the  Company  has  knowledge  (whether completed  or  pending)  seeking the
     recall, withdrawal,  suspension or  seizure of  any Pharmaceutical  Product
     pending  against the Company at any time during the period commencing April
     1, 1991 and ending on the date hereof.
 
          (iii) Schedule 3.01(g) delivered by the Company to Parent sets forth a
     list of each of  the Company's pending and  approved New Drug  Applications
     ('NDAs'),  Investigational New Drug  applications ('INDs'), Abbreviated New
     Drug  Applications  ('ANDAs'),  New  Animal  Drug  Applications  ('NADAs'),
     Abbreviated  New Animal Drug Applications ('ANADAs') or Investigational New
     Animal Drug applications ('INADs') as of the date hereof. True and complete
     copies of such NDAs,  INDs, ANDAs, NADAs, ANADAs  and INADs, including  all
     supplements,  amendments,  and annual  reports,  have heretofore  been made
     available to  Parent.  Copies  of  correspondence  from  the  FDA  and  the
     Company's  response have  heretofore been made  available to  Parent. As to
     each drug for which such an  application has been approved, the Company  is
     in  substantial compliance with  21 U.S.C. SSSS355, 357  or 360b, 21 C.F.R.
     Parts 312, 314 or 430 et. seq., 512, or 514 et seq., respectively, and  all
     terms  and  conditions of  such  applications. As  to  each such  drug, the
     Company and any relevant Subsidiary, and the officers, employees or  agents
     of the Company or such Subsidiary have included in the application for such
     drug, where required, the certification described in 21 U.S.C. SS335a(k)(1)
     and  the list described  in 21 U.S.C.  SS335a(k)(2), and such certification
     and such list was  in each case  true and accurate  when made and  remained
     true  and accurate thereafter.  In addition, the  Company is in substantial
     compliance with all  applicable registration and  listing requirements  set
     forth in 21 U.S.C. SS360 and 21. C.F.R. Part 207.
 
          (iv)  Each  article of  drug  manufactured and/or  distributed  by the
     Company or  any Subsidiary  is not  adulterated within  the meaning  of  21
     U.S.C.  SS351 or misbranded within  the meaning of 21  U.S.C. SS352, and is
     not a product that is in violation of 21 U.S.C. SS355.
 
          (v) Schedule 3.01(g) delivered by the  Company to Parent sets forth  a
     list  of (A)  Form 483s,  (B) Notices of  Adverse Findings  and (C) warning
     letters or other correspondence from the FDA in which the FDA asserted that
     the operations of the  Company or any Subsidiary  may not be in  compliance
     with  applicable  law,  in  each  case  received  by  the  Company  or such
     Subsidiary from the
 
                                      A-8
 
<PAGE>
 
<PAGE>
     FDA since April 1, 1991 to the date hereof and the response of the  Company
     or  such  Subsidiary to  the FDA  to such  notices from  the FDA.  True and
     complete copies of such Form 483s, Notices of Adverse Findings, letters and
     other correspondence  and  the  Company's or  Subsidiary's  responses  have
     heretofore  been  made  available to  Parent.  Except as  disclosed  in the
     Company Commission Filings or otherwise set forth in Schedule 3.01(g),  all
     manufacturing  operations of the Company and the Subsidiaries have been and
     are being conducted in substantial  compliance with the good  manufacturing
     practice regulations set forth in 21 C.F.R. Parts 210 and 211.
 
          (vi)  Schedule 3.01(g) delivered  by the Company  to Parent sets forth
     Adverse Reaction  Reports filed  by the  Company with  the FDA  during  the
     period commencing April 1, 1991 and ending on the date hereof.
 
          (vii)  Neither  the  Company,  nor any  Subsidiary,  nor  any officer,
     employee or  agent of  either the  Company or  any Subsidiary  has made  an
     untrue  statement of  a material fact  or fraudulent statement  to the FDA,
     failed to disclose a material fact required to be disclosed to the FDA,  or
     committed  an act, made a statement, or failed to make a statement that, at
     the time such disclosure was made, could reasonably be expected to  provide
     a  basis  for  the  FDA  to invoke  its  policy  respecting  'Fraud, Untrue
     Statements of Material Facts, Bribery,  and Illegal Gratuities', set  forth
     in  56 Fed. Reg. 46191 (September 10, 1991). Neither the Company nor any of
     the Subsidiary, nor any officer, employee or agent of either the Company or
     any Subsidiary has been  convicted of any crime  or engaged in any  conduct
     for  which debarment is mandated by 21 U.S.C. SS335a(a) or authorized by 21
     U.S.C. SS335a(b).
 
          (viii) Except as disclosed in the Company Commission Filings,  neither
     the Company nor any Subsidiary has received any written notice that the FDA
     has  commenced,  or  threatened to  initiate,  any action  to  withdraw its
     approval or  request  the recall  of  any product  of  the Company  or  any
     Subsidiary,  or commenced, or overtly threatened to initiate, any action to
     enjoin production at any facility of the Company or any Subsidiary.
 
          (ix) All  Drug Master  Files  ('DMFs') submitted  to  the FDA  by  the
     Company  or any  Subsidiary for bulk  drug ingredients  manufactured by the
     Company or  such Subsidiary  are up-to-date  and accurately  represent  the
     Company's  current manufacturing operations to  the extent required by law;
     and all persons authorized to reference the DMFs and FDA have been notified
     of any changes  of information  in the DMFs  in accordance  with 21  C.F.R.
     SS314.420(c).
 
          (x)  The  Company  is  in  substantial  compliance  with  the Medicare
     Anti-kickback  Statute,   42   U.S.C.   SS1320a-7b(b),   and   implementing
     regulations codified at 42 C.F.R. SS1001.
 
          (h)  Compliance  with  Laws.  (i)  General.  Except  with  respect  to
     regulatory matters  (which  are  covered  exclusively  by  Section  3.01(g)
     hereof) and environmental matters (which are covered exclusively by Section
     3.01(h)(ii) below), the Company and the Subsidiaries are in compliance with
     all  applicable laws,  regulations, orders,  judgments and  decrees, except
     where the failure to so comply would not have a material adverse effect  on
     the Condition of the Company and the Subsidiaries taken as a whole.
 
          (ii)  Environmental Matters. Except to  the extent that the inaccuracy
     of any  of  the  following  (or  the  circumstances  giving  rise  to  such
     inaccuracy),  individually  or in  the aggregate,  would not  reasonably be
     expected to have a material adverse effect on the Condition of the  Company
     and  the  Subsidiaries taken  as  a whole  (after  taking into  account any
     reserves  therefor  reflected  in  the  most  recent  financial  statements
     included  in the Company Commission Filings filed prior to the date hereof)
     ('Material Adverse Effect') or as  set forth on Schedule 3.01(h)(ii),  none
     of   which  scheduled  items  would  reasonably,  individually  or  in  the
     aggregate, be expected to have a Material Adverse Effect:
 
             (A) The  Company and  the Subsidiaries  hold, or  have made  timely
        application  to  renew, and  are in  compliance with,  all Environmental
        Permits, and the Company and the Subsidiaries are in compliance with all
        applicable Environmental Laws;
 
                                      A-9
 
<PAGE>
 
<PAGE>
             (B) There currently are no circumstances known to the Company which
        would reasonably be expected to prevent or interfere with compliance  in
        the future with Environmental Permits and applicable Environmental Laws;
 
             (C) None of the Company or the Subsidiaries has received notice of,
        nor  to  the knowledge  of the  Company is  there threatened  or pending
        against the Company or any of the Subsidiaries, any Environmental Claim,
        nor  are  there  currently  any  circumstances,  conditions  or  events,
        including,  without  limitation,  any  treatment,  storage,  disposal or
        release of Hazardous  Materials, that  would reasonably  be expected  to
        give  rise to an Environmental  Claim against the Company  or any of the
        Subsidiaries;
 
             (D) None of  the Company or  the Subsidiaries has  entered into  or
        agreed to any consent decree or order under any applicable Environmental
        Law  that is currently  outstanding, pending or  unresolved, and none of
        the Company or the Subsidiaries is the subject of any pending or, to the
        knowledge of the Company, threatened  judgment, decree, or order of  any
        environmental  governmental  authority relating  to compliance  with any
        applicable Environmental Law or  to investigation, cleanup,  remediation
        or  removal of  Hazardous Materials  under any  applicable Environmental
        Law;
 
             (E)  There   are   no   (i)   underground   storage   tanks,   (ii)
        polychlorinated   biphenyls,   (iii)   friable   asbestos   or   friable
        asbestos-containing materials or  (iv) Hazardous  Materials present  on,
        at,  beneath or near any facility currently or formerly owned, leased or
        operated by  the Company  or any  of the  Subsidiaries, except  for  any
        Hazardous  Materials maintained and stored in compliance with applicable
        Environmental Laws for use in the ordinary course of the business of the
        Company or the Subsidiaries, any  of which would reasonably be  expected
        to give rise to an Environmental Claim against the Company or any of the
        Subsidiaries under any Environmental Laws;
 
             (F) There are no past or present conditions or circumstances at any
        real  property presently  or formerly owned,  leased or  operated by the
        Company or any  of the  Subsidiaries, including  without limitation  the
        release, threatened release, emission, discharge, generation, treatment,
        storage  or disposal  of Hazardous  Materials, that  would reasonably be
        expected to give rise to an  Environmental Claim against the Company  or
        any of the Subsidiaries;
 
             (G)  Neither  the  Company  nor  any  Subsidiary  has  assumed  any
        liability relating  to  Environmental  Claims pursuant  to  any  written
        contracts  or agreements between the Company  or any of the Subsidiaries
        and any third party;
 
             (H) No liens have been placed upon any assets of the Company or the
        Subsidiaries in connection  with any actual  or alleged liability  under
        any Environmental Law; and
 
             (I)  To  the  knowledge  of the  Company,  other  than  the filings
        required to secure the  ISRA Clearance, neither the  Company nor any  of
        the  Subsidiaries is required to give notice  of or record or deliver to
        any governmental  authority  an  environmental  disclosure  document  or
        statement   under  applicable  Environmental  Laws   by  virtue  of  the
        transactions contemplated by this  Agreement, or as  a condition to  the
        recording  of any mortgage or to ensure  the effectiveness of any of the
        transactions contemplated hereby.
 
     For purposes  of  this  Agreement,  the  following  terms  shall  have  the
     following meanings:
 
          'Environmental Claim' means any written or oral notice, claim, demand,
     action,  suit, complaint, proceeding or  other communication by any Person,
     including, without  limitation, any  federal, state  or local  governmental
     authority,  alleging liability or potential liability of the Company or any
     of the Subsidiaries  (including without limitation  liability or  potential
     liability  for  emergency  actions,  investigatory  costs,  cleanup  costs,
     governmental response  costs, natural  resource damages,  property  damage,
     personal  injury, fines or penalties) arising out of, relating to, based on
     or resulting  from  (i)  the  presence,  discharge,  emission,  release  or
     threatened  release of any Hazardous Materials  at any location, whether or
     not owned, leased or operated by the Company or any of the Subsidiaries, or
     (ii) circumstances forming the basis of any violation or alleged  violation
     of any Environmental Law or Environmental Permit.
 
                                      A-10
 
<PAGE>
 
<PAGE>
          'Environmental  Laws' means  all applicable federal,  state, local and
     foreign statutes, rules, regulations,  ordinances, orders, decrees and  the
     common  law  relating  in any  manner  to the  contamination,  pollution or
     protection of human health and safety or the environment including  without
     limitation  the  Comprehensive  Environmental  Response,  Compensation  and
     Liability Act, the Solid Waste Disposal Act, the Resource Conservation  and
     Recovery  Act, the Clean Air Act, the  Clean Water Act, the Toxic Substance
     Control Act, the Occupational Safety and Health Act, the Emergency Planning
     and Community-Right-to-Know  Act,  the Safe  Drinking  Water Act,  the  New
     Jersey  Industrial Site Recovery Act, the  New Jersey Air Pollution Control
     Act, the New Jersey Water Pollution Control Act, the New Jersey Solid Waste
     Management Act, the New Jersey Pollution Prevention Act, the Missouri Solid
     Waste Law,  the  Missouri  Hazardous Waste  Management  Law,  the  Missouri
     Underground  Storage Tank Law,  the Missouri Clean  Water Act, the Missouri
     Air Conservation Law, all as amended, and similar state laws.
 
          'Environmental  Permits'  means  all  permits,  consents,   approvals,
     variances,  licenses, registrations  and other  governmental authorizations
     issued by  an  environmental regulatory  agency,  authority or  entity  and
     required  for  the Company  and  the operations  of  the Company's  and the
     Subsidiaries'  facilities,  and  otherwise  to  conduct  their   respective
     businesses under Environmental Laws.
 
          'Hazardous Materials' means all hazardous or toxic substances, wastes,
     materials  or  chemicals, petroleum  (including crude  oil or  any fraction
     thereof)  and   petroleum   products,  asbestos   and   asbestos-containing
     materials,  pollutants, contaminants,  which are regulated  pursuant to any
     applicable Environmental Law and such other materials and substances as are
     regulated pursuant to any applicable Environmental Laws.
 
          (i) Litigation. Except as disclosed in the Company Commission  Filings
     or as set forth on Schedule 3.01(i) delivered to Parent by the Company, and
     except with respect to environmental matters (which are covered exclusively
     in Section 3.01(h)(ii) hereof), there is no action, suit, proceeding at law
     or  in equity, or any arbitration or any administrative or other proceeding
     by or before (or to the knowledge of the Company any investigation by)  any
     governmental  or  other  instrumentality  or agency,  pending,  or,  to the
     knowledge of the Company, threatened,  against or affecting the Company  or
     any  of the  Subsidiaries, or  any of their  properties or  rights which if
     adversely determined would be reasonably likely to have a material  adverse
     effect  on the  Condition of  the Company and  the Subsidiaries  taken as a
     whole. Except as  disclosed in  the Company Commission  Filings and  except
     with  respect to  environmental matters  (which are  covered exclusively in
     Section  3.01(h)(ii)  hereof),   neither  the  Company   nor  any  of   the
     Subsidiaries  is subject  to any judgment,  order or decree  entered in any
     lawsuit or proceeding which is reasonably likely to have a material adverse
     effect on the  Condition of  the Company and  the Subsidiaries  taken as  a
     whole  or on the  ability of the  Company or any  Subsidiary to conduct its
     business as presently conducted.
 
          (j) Employee  Benefit Plans.  (i) Schedule  3.01(j) delivered  by  the
     Company  to Parent sets forth: (x) all 'employee benefit plans,' as defined
     in Section 3(3) of the Employee Retirement Income Security Act of 1974,  as
     amended ('ERISA'), and all other employee benefit arrangements, policies or
     payroll  practices,  including,  without  limitation,  severance  pay, sick
     leave,  vacation  pay,  salary  continuation  for  disability,  retirement,
     deferred   or   other  executive   compensation,  bonus,   stock  purchase,
     hospitalization,  medical   insurance,  life   insurance  and   scholarship
     programs,  maintained by the Company or any of the Subsidiaries or to which
     the Company or any such Subsidiary has contributed in the past three  years
     or is obligated to contribute thereunder for current or former employees of
     the  Company or any such Subsidiary in each case, excluding plans disclosed
     under the immediately following clause (y) (the 'Employee Benefit  Plans'),
     and  (y) all 'employee pension plans,' as defined in Section 3(2) of ERISA,
     subject either  to  Section  412 of  the  Code  or to  Title  IV  of  ERISA
     maintained by the Company, any of the Subsidiaries or any trade or business
     (whether or not incorporated) which are or have at any time within the last
     six  years been  under common  control, or  which are  or have  at any time
     within the  last six  years been  treated  as a  single employer  with  the
     Company  under  Section  414(b),  (c),  (m)  or  (o)  of  the  Code ('ERISA
 
                                      A-11
 
<PAGE>
 
<PAGE>
     Affiliate') or to which the Company,  any of the Subsidiaries or any  ERISA
     Affiliate  contributed or has  at any time  within the last  six years been
     obligated to contribute (the 'Pension Plans').
 
          (ii) None  of  the Company,  any  of  the Subsidiaries  or  any  ERISA
     Affiliate  has  withdrawn  in a  complete  or partial  withdrawal  from any
     Pension Plan which is a multiemployer plan, as defined in Section 3(37)  of
     ERISA  (each such  Pension Plan  being defined  herein as  a 'Multiemployer
     Plan'), prior  to the  Effective Time,  nor has  any of  them received  any
     notice  from  a  Multiemployer  Plan  that any  of  them  has  incurred any
     liability due to the termination or reorganization of a Multiemployer Plan.
     Parent will  not have  (i) except  as  set forth  in Schedule  3.01(j)  any
     obligation  to make any contribution to  any Multiemployer Plan or (ii) any
     withdrawal liability from any such Multiemployer Plan under Section 4201 of
     ERISA which it  would not have  had had  it not consummated  the Merger  in
     accordance with the provisions of this Agreement.
 
          (iii)  Each Employee Benefit Plan and Pension Plan intended to qualify
     under Section 401 of the Code, other than Multiemployer Plans, has received
     a determination letter from the Internal Revenue Service ('IRS') that  each
     such  Employee Benefit Plan or  Pension Plan is so  qualified and the trust
     maintained pursuant thereto  is exempt from  federal income taxation  under
     Section 501 of the Code, and, to the best knowledge of the Company, nothing
     has  occurred with respect to the operation of such Plans which could cause
     the loss  of such  qualification  or exemption  or  the imposition  of  any
     liability, penalty or tax under ERISA or the Code.
 
          (iv)  All  contributions  (including  all  employer  contributions and
     employee salary reduction contributions) required to have been made by  the
     Company  or the  Subsidiaries under  any of  the Employee  Benefit Plans or
     Pension Plans  or by  law  (without regard  to  any waivers  granted  under
     Section  412 of the Code) to any  funds or trusts established thereunder or
     in connection therewith have been made  by the due date thereof  (including
     any  valid extension),  and all contributions  for any period  ending on or
     before the Effective  Time which are  not yet  due will have  been paid  or
     accrued  on  or  prior  to  the  Effective  Time.  No  accumulated  funding
     deficiencies exist in any  of the Pension Plans  subject to Section 412  of
     the Code, other than any Multiemployer Plan.
 
          (v) There is no 'amount of unfunded benefit liabilities' as defined in
     Section  4001(a)(18)  of ERISA  in  any of  the  Pension Plans,  other than
     Multiemployer  Plans,  as  determined  in  accordance  with  the  actuarial
     assumptions  used  by  the  Pension Benefit  Guaranty  Corporation,  or any
     successor thereof ('PBGC'), to determine  the level of funding required  in
     the event of the termination of the Pension Plan.
 
          (vi)  There has been no 'reportable event,' as that term is defined in
     Section 4043 of ERISA and the  regulations thereunder, with respect to  any
     Pension Plan which would require the giving of notice of an event requiring
     disclosure under Section 40 41(c)(3)(C) or 4063(a) of ERISA.
 
          (vii)  There is  no material  violation of  ERISA with  respect to the
     filing of applicable reports, documents and notices regarding the  Employee
     Benefit  Plans or Pension  Plans; other than  Multiemployer Plans, with the
     Secretary of Labor or  the Secretary of the  Treasury or the furnishing  of
     such documents to the participants or beneficiaries of the Employee Benefit
     Plans or Pension Plans.
 
          (viii)  True, correct and  complete copies of  the following documents
     (where applicable), with respect to each of the Employee Benefit Plans  and
     Pension  Plans,  other  than,  as  to  clauses  (iii)  through  (vi) below,
     Multiemployer Plans, have been delivered or made available to Parent by the
     Company: (i) all plans and related trust documents, and amendments thereto;
     (ii) the most recent Forms 5500;  (iii) the last IRS determination  letter;
     (iv)   summary   plan  descriptions;   (v)   all  other   material  written
     communications addressed to employees  as a group from  the Company or  any
     Subsidiary  to employees relating to the Employee Benefit Plans and Pension
     Plans distributed within the last 12 months; and (vi) written  descriptions
     of  all unwritten  agreements relating  to the  Employee Benefit  Plans and
     Pension Plans.
 
          (ix) There are no pending actions, claims or lawsuits which have  been
     asserted  or instituted against the Employee Benefit Plans or Pension Plans
     (other than any Multiemployer  Plan, unless such  action, claim or  lawsuit
     relates  to  action  or  inaction  on  the  part  of  the  Company  or  any
 
                                      A-12
 
<PAGE>
 
<PAGE>
     Subsidiary), the assets of any of the  trusts under such plans or the  plan
     sponsor  or the  plan administrator, or  against any fiduciary  of any such
     Employee Benefit Plan or Pension Plan with respect to the operation of such
     plans (other than  routine benefit claims),  nor does the  Company, or  any
     Subsidiary  have knowledge of  facts which could  reasonably be expected to
     form the basis for any such claim or lawsuit.
 
          (x) All amendments and actions required to bring the Employee  Benefit
     Plans and Pension Plans, other than any Multiemployer Plan, into conformity
     in all material respects with all of the applicable provisions of ERISA and
     other  applicable laws have  been made or  taken except to  the extent that
     such amendments or  actions are not  required by  law to be  made or  taken
     until a date after the Closing Date.
 
          (xi)  Any bonding required with respect  to the Employee Benefit Plans
     and Pension Plans, other  than any Multiemployer  Plan, in accordance  with
     applicable  provisions of ERISA has been obtained  and is in full force and
     effect.
 
          (xii) The Employee  Benefit Plans  and Pension Plans,  other than  any
     Multiemployer  Plan,  have  been  maintained in  all  material  respects in
     accordance with their  terms and  with all applicable  provisions of  ERISA
     (including  rules and regulations thereunder)  and other applicable federal
     and state laws  and regulations,  and neither the  Company nor  any of  the
     Subsidiaries  or 'party in interest'  or 'disqualified person' with respect
     to any  such  Employee  Benefit Plan  or  Pension  Plan has  engaged  in  a
     'prohibited  transaction' within the meaning of Section 4975 of the Code or
     Section 406 of ERISA. No fiduciary who is a Company or Subsidiary  employee
     has  any liability for breach of fiduciary duty or any other failure to act
     or comply in connection with the administration or investment of the assets
     of any Employee Benefit Plan or Pension Plan.
 
          (xiii) Neither the Company, nor any  of the Subsidiaries or any  ERISA
     Affiliate has within the last six years terminated any Pension Plan subject
     to  Title IV, or  incurred any outstanding liability  under Section 4062 of
     ERISA to the PBGC, or to a  trustee appointed under Section 4042 of  ERISA.
     All  premiums due the PBGC from the  Company or any Subsidiary prior to the
     date hereof with respect to the Employee Benefit Plans have been paid.
 
          (xiv) Neither  the  Company  nor any  of  the  Subsidiaries  maintains
     retiree  life or retiree health insurance  plans which are Employee Benefit
     Plans which provide for continuing benefits or coverage for any participant
     or any beneficiary of a participant except as may be required under Section
     4980B of the Code and Section 601 of ERISA and the regulations  thereunder.
     The  Company, each  Subsidiary and each  ERISA Affiliate  which maintains a
     'group health plan'  within the meaning  of Section 4980B  of the Code  has
     complied  in  all  material  respects  with  the  notice  and  health  care
     continuation requirements of Section 4980B of  the Code and Section 601  of
     ERISA and the regulations thereunder.
 
          (xv)  Neither  the Company,  nor any  of  the Subsidiaries,  any ERISA
     Affiliate or any organization to which  the Company or any such  Subsidiary
     or ERISA Affiliate is a successor or parent corporation, within the meaning
     of  Section  4069(b) of  ERISA,  has engaged  in  any transaction  to evade
     liability within the meaning of Section 4069 of ERISA.
 
          (xvi) No liability  under any  Employee Benefit Plan  or Pension  Plan
     other than a Multiemployer Plan has been funded nor has any such obligation
     been  satisfied with the  purchase of a contract  from an insurance company
     that is not rated AA by Standard & Poor's Corporation or the equivalent  by
     at least one nationally recognized rating agency.
 
          (xvii) Except as otherwise contemplated by this Agreement, neither the
     execution  and  delivery  of this  Agreement  nor the  consummation  of the
     transactions contemplated hereby  will (i) result  in any payment  becoming
     due  to any employee (current, former or  retired) of the Company or any of
     the Subsidiaries, (ii)  increase any benefits  otherwise payable under  any
     Employee  Benefit Plan or Pension Plan  or (iii) result in the acceleration
     of the time of  payment or vesting  of any such  benefits. Any amount  that
     could  be received as a  result of any of  the transactions contemplated by
     this Agreement by any employee, officer  or director of the Company or  any
     Subsidiary  who is a 'disqualified individual'  (as such term is defined in
     proposed Treasury Regulation SS1.280G-1)
 
                                      A-13
 
<PAGE>
 
<PAGE>
     under  any   employment,   severance  or   termination   agreement,   other
     compensation plan or Employee Benefit Plan currently in effect would not be
     characterized  as an 'excess parachute payment' (as such term is defined in
     SS280G(b)(1) of the Code.)
 
          (xviii) None  of  the Company  or  any  of the  Subsidiaries  has  any
     contract, plan or commitment, whether legally binding or not, to create any
     additional  Employee Benefit Plan or Pension Plan or to modify any existing
     Employee Benefit Plan or Pension Plan, except as may be required by law  or
     under the terms of a collective bargaining agreement.
 
          (xix)  Except as set  forth on Schedule  3.01(j)(xix) delivered by the
     Company to Parent, no stock or other security issued by the Company or  any
     of  the  Subsidiaries forms  or  has formed  a part  of  the assets  of any
     Employee Benefit Plan or Pension Plan.
 
          (xx) Except  as set  forth on  Schedule 3.01(j)(xx)  delivered by  the
     Company  to Parent, neither the Company nor any of the Subsidiaries has any
     liability or obligation, accrued or unaccrued, contingent or otherwise,  to
     any former employee of the Company or any Subsidiary.
 
          (xxi) There has been no 'mass layoff' or 'plant closing' as defined by
     the Worker Adjustment and Retraining Notification Act and any similar state
     or  local 'plant closing' law with respect  to the employees of the Company
     or any Subsidiary.
 
          (k) Employment Agreements.  Except as  set forth  on Schedule  3.01(k)
     delivered  to Parent by  the Company, there  exists (i) no  union, guild or
     collective bargaining agreement to which the Company or any Subsidiary is a
     party, (ii) no  employment, consulting or  severance agreement between  the
     Company  and  any  director,  officer  or  employee  of  the  Company which
     agreement is not stated to be terminable upon twelve or less months' notice
     except for agreements pursuant to which the per annum salary (excluding any
     bonuses or performance based  compensation) of the  employee party to  such
     agreement  does not exceed $100,000 and the remaining term thereof does not
     exceed  two  years  or  (iii)  no  employment,  consulting,  severance   or
     indemnification agreement to which the Company or any Subsidiary is a party
     that  would be altered as a result  of the Merger or the other transactions
     contemplated hereby.
 
          (l) Taxes. Except as set forth in Schedule 3.01(l) delivered to Parent
     by the Company: (i) the Company has filed or caused to be filed, within the
     times (including authorized  extensions) and  in the  manner prescribed  by
     law,  all federal,  state, local  and foreign  tax returns  and tax reports
     which are required to be filed by,  or with respect to, the Company or  any
     of  the Subsidiaries;  (ii) all federal,  state, local  and foreign income,
     profits, franchise,  sales,  use, occupancy,  excise  and other  taxes  and
     assessments (including interest and penalties) payable by, or due from, the
     Company  or any  of the Subsidiaries  have been, in  all material respects,
     fully paid or adequately disclosed and fully provided for in the books  and
     financial statements of the Company and the Subsidiaries; (iii) the federal
     income  tax liability of the Company  and the Subsidiaries has been finally
     determined for all  fiscal years  to and  including the  fiscal year  ended
     March  31, 1990; (iv) the Company has received no notice of any examination
     of any  tax return  of  the Company  or any  of  the Subsidiaries  that  is
     currently  in  progress; and  (v) there  are  no outstanding  agreements or
     waivers extending the statutory period of limitation applicable to any  tax
     return of the Company or any of the Subsidiaries.
 
          (m)  Absence  of  Undisclosed  Liabilities.  Except  with  respect  to
     environmental matters (which are covered exclusively in Section 3.01(h)(ii)
     hereof) and regulatory  matters (which are  covered exclusively in  Section
     3.01(g)  hereof), neither the  Company nor any of  the Subsidiaries has any
     material indebtedness or material liability, absolute or contingent, direct
     or indirect, which is required in  accordance with US GAAP to be  reflected
     on the consolidated balance sheet of the Company and its subsidiaries as of
     September 30, 1995 contained in the Company Commission Filings or otherwise
     disclosed  in  the Company  Commission  Filings other  than  liabilities so
     reflected or disclosed  or incurred or  accrued in the  ordinary course  of
     business  (including liens of current taxes and assessments not in default)
     since that date. Except as shown in  such balance sheet or in the notes  to
     the  financial  statements contained  in  such Company  Commission Filings,
     neither the Company nor any of  the Subsidiaries is directly or  indirectly
     liable  upon  or with  respect to  (by  discount, repurchase  agreements or
     otherwise),  or  obligated   in  any   other  way  to   provide  funds   in
 
                                      A-14
 
<PAGE>
 
<PAGE>
     respect  of, or  to guarantee or  assume, any material  debt, obligation or
     dividend of  any Person,  except  endorsements in  the ordinary  course  of
     business in connection with the deposit of items for collection.
 
          (n)  Transactions with  Directors, Officers and  Affiliates. Except as
     disclosed in Schedule 3.01(n) delivered by the Company to Parent or in  the
     Company  Commission  Filings,  since March  31,  1991, there  have  been no
     transactions between  the  Company  or  any of  the  Subsidiaries  and  any
     director,  officer, employee, stockholder or  other 'Affiliate' (as defined
     in Rule 405 under the Securities  Act of 1933, as amended (the  'Securities
     Act'))  of  the  Company or  any  of the  Subsidiaries,  including, without
     limitation, loans, guarantees or  pledges to, by or  for the Company  from,
     to,  by or for  any of such  Persons. Except as  disclosed in such Schedule
     3.01(n) or in the Company Commission Filings, since March 31, 1991, none of
     the officers or directors of the Company or any of the Subsidiaries, or any
     spouse or relative of any of such  Persons, has been a director or  officer
     of,  or has  had any  material direct  or indirect  interest in,  any firm,
     corporation, association or  business enterprise which  during such  period
     has  been a supplier, customer or sales agent  of the Company or any of its
     subsidiaries or has competed  with or been engaged  in any business of  the
     kind being conducted by the Company or any of the Subsidiaries.
 
          (o)  Broker's or Finder's  Fee. Except for Goldman  Sachs & Co. (whose
     fees and expenses as financial advisors to the Company will be paid by  the
     Company  in accordance with the Company's  agreement with such firm, a true
     and correct copy of  which has been previously  delivered to Parent by  the
     Company),  no agent, broker, Person or firm acting on behalf of the Company
     or Harold Snyder, Beatrice Snyder, Beryl L. Snyder, Brian S. Snyder or  Jay
     T.  Snyder is, or will  be, entitled to any  fee, commission or broker's or
     finder's  fees  from  any  of  the  parties  hereto,  or  from  any  Person
     controlling, controlled by, or under common control with any of the parties
     hereto,  in  connection  with this  Agreement  or any  of  the transactions
     contemplated hereby.
 
          (p) Opinion of Financial Advisor. The Company has received the opinion
     of Goldman Sachs & Co.,  dated the date hereof, to  the effect that, as  of
     such date, the Exchange Ratio is fair to the Company's stockholders.
 
          (q)  Vote Required. The approval of the Merger by the affirmative vote
     of two-thirds  of the  votes  that holders  of  the outstanding  shares  of
     Company  Common Stock are entitled to cast  is the only vote of the holders
     of any class or series of the Company's capital stock necessary to  approve
     the transactions contemplated hereby.
 
          (r)  Material Contracts. Schedule 3.01(r) lists all material contracts
     and agreements  to  which,  as of  the  date  hereof, the  Company  or  any
     Subsidiary  is a  party which  were not  filed as  exhibits to  the Company
     Commission Filings,  which  are  not  cancelable  by  the  Company  or  its
     Subsidiary  on less than 60 days' notice and which involve or relate to (i)
     obligations of the Company or any  Subsidiary for borrowed money where  the
     amount  of such obligations exceeds $50,000 individually, (ii) the lease by
     the Company or any  Subsidiary, as lessee or  lessor, of real property  for
     rent  of more than $10,000  per annum, (iii) the  purchase or sale of goods
     (other than raw material to be purchased  by the Company in amounts and  at
     prices  substantially  consistent with  past practices  of the  Company) or
     services with an aggregate minimum purchase price of more than $100,000 per
     annum, (iv)  rights to  manufacture  and/or distribute  any  Pharmaceutical
     Product  which accounted for more than $50,000 of the consolidated revenues
     of the Company and the Subsidiaries during the fiscal year ended March  31,
     1995  or under which the Company or any Subsidiary received or paid license
     or other fees in  excess of $50,000  during the said  fiscal year, (v)  the
     purchase  or sale  of assets  or properties not  in the  ordinary course of
     business having a purchase price in  excess of $100,000 or (vi)  individual
     capital  expenditures  or  commitments  in  excess  of  $100,000.  All such
     contracts and agreements are  duly and validly executed  by the Company  or
     such  Subsidiary, and are in  full force and effect.  No event has occurred
     which, after notice  or the  passage of time  or both,  would constitute  a
     material  default under any such contract or agreement. Except as disclosed
     on Schedule 3.01(r), all such contracts and agreements will continue, after
     the Effective Time, to be binding in accordance with their respective terms
     until their respective expiration dates.
 
                                      A-15
 
<PAGE>
 
<PAGE>
          (s) Accounting Matters. The  Company knows of  no reasons, within  its
     control,  why the Merger will not be  capable of being treated as a pooling
     of interest transaction under APB 16. The Company has not taken any  action
     that  will prevent the Merger from being  recorded as a pooling of interest
     transaction under APB 16.
 
          (t) Tax Matters. The Company knows of no fact or circumstance which is
     reasonably likely  to  cause the  Merger  to be  treated  other than  as  a
     tax-free reorganization under Section 368(a)(1)(A) of the Code by virtue of
     Section 368(a)(2)(E) of the Code.
 
     3.02  Representations  and Warranties  of Parent  and  Sub. Parent  and Sub
represent and warrant to the Company as follows:
 
          (a) Due Organization, Good Standing and Power. Each of Parent and  its
     subsidiaries  is a corporation  duly organized and  validly existing and in
     good standing  (where applicable)  under the  laws of  its jurisdiction  of
     organization  and  each  such  corporation  has  all  requisite  power  and
     authority to own,  lease and  operate its properties  and to  carry on  its
     business  as now  being conducted. Each  of Parent and  its subsidiaries is
     duly qualified or licensed  to do business and  is in good standing  (where
     applicable)  in each  jurisdiction in which  the property  owned, leased or
     operated by it  or the nature  of the  business conducted by  it make  such
     qualification  necessary, except in such jurisdictions where the failure to
     be so qualified or licensed and  in good standing (where applicable)  would
     not  have a  material adverse  effect on  the Condition  of Parent  and its
     subsidiaries taken as a whole.
 
          (b) Authorization and Validity  of Agreement. Each  of Parent and  Sub
     has  full power  and authority  to execute  and deliver  this Agreement, to
     perform its  obligations  hereunder  and  to  consummate  the  transactions
     contemplated  hereby.  The  execution,  delivery  and  performance  of this
     Agreement by each  of Parent and  Sub, and  the consummation by  it of  the
     transactions contemplated hereby, have been duly authorized by the Board of
     Directors  of each of Parent  and Sub and no  other corporate action on the
     part of either of  Parent or Sub is  necessary to authorize the  execution,
     delivery  and performance of this  Agreement by each of  Parent and Sub and
     the consummation of  the transactions contemplated  hereby. This  Agreement
     has  been duly executed  and delivered by each  of Parent and  Sub and is a
     valid and binding obligation of each of Parent and Sub, enforceable against
     each of  Parent and  Sub in  accordance with  its terms,  except that  such
     enforcement   may   be  limited   by  applicable   bankruptcy,  insolvency,
     reorganization, moratorium  or  other  similar  laws  affecting  creditors'
     rights generally, and general equitable principles.
 
          (c)  Capitalization.  (i)  The  authorized  share  capital  of  Parent
     consists of 992,930,000 Ordinary Shares. As of December 31, 1995, (i) there
     were 554,228,366 Ordinary Shares issued  and outstanding and (ii)  employee
     share  options to subscribe  for an aggregate  of 6,219,966 Ordinary Shares
     were outstanding. All such issued  Ordinary Shares and all Ordinary  Shares
     issued in connection with the Merger have been, or will be, as the case may
     be,  duly authorized and validly issued as  fully paid or credited as fully
     paid and were not and, in the case of Ordinary Shares issued in  connection
     with  the Merger, will not have been, issued in violation of any preemptive
     right. Except as set forth in  this Section 3.02(c) or on Schedule  3.02(c)
     delivered  to the Company  by Parent and except  for changes since December
     31, 1994 resulting from the exercise of employee share options  outstanding
     on such date, (i) there is no share capital of Parent authorized, issued or
     outstanding  and  (ii) there  are not  as of  the date  hereof, and  at the
     Effective Time  there  will  not be,  any  outstanding  options,  warrants,
     rights,  subscriptions, claims  of any  character, agreements, obligations,
     convertible or exchangeable securities, or other commitments, contingent or
     otherwise, relating  to  Ordinary Shares  or  any other  share  capital  of
     Parent,  pursuant to which  Parent is or  may become obligated  to issue or
     purchase or otherwise acquire Ordinary Shares or any other share capital or
     securities convertible into, exchangeable for,  or evidencing the right  to
     subscribe for, any share capital of Parent.
 
          (ii)  All  of  the outstanding  shares  of  capital stock  of  each of
     Parent's subsidiaries (other than directors' qualifying shares) except  for
     subsidiaries  with  no material  assets  or liabilities  have  been validly
     issued as  fully  paid  or credited  as  fully  paid, were  not  issued  in
     violation of any preemptive
 
                                      A-16
 
<PAGE>
 
<PAGE>
     rights  and are beneficially owned, directly or indirectly, by Parent, free
     and clear of all liens, encumbrances, options or claims whatsoever.
 
          (d) Consents  and  Approvals; No  Violations.  Assuming that  (i)  the
     filings  required  under  the  HSR  Act are  made  and  the  waiting period
     thereunder has been terminated or has expired; (ii) the filing of the Proxy
     Statement is made and the  Registration Statement and the F-6  Registration
     Statement  are declared effective;  (iii) the filing  of the Certificate of
     Merger and other appropriate merger documents,  if any, as required by  the
     laws of the State of Delaware is made; (iv) any applicable state securities
     or  Blue Sky  laws are  complied with;  and (v)  the Controller  of Foreign
     Currency of the Bank of Israel has approved the Merger, the issuance of the
     Ordinary  Shares  in  connection  therewith  and  the  other   transactions
     contemplated by this Agreement, the Israeli Securities Authority has issued
     the  required permit to publish the Proxy Statement or granted an exemption
     from such  requirement,  and  the  Tel Aviv  Stock  Exchange  ('TASE')  has
     delivered  an  agreement in  principle to  list the  Ordinary Shares  to be
     issued  in  connection  with  the  transactions  contemplated  hereby,  the
     execution  and  delivery  of  this  Agreement by  Parent  and  Sub  and the
     consummation by Parent and Sub of the transactions contemplated hereby will
     not: (1) violate any provision of the Memorandum of Association or Articles
     of Association of Parent or the Certificate of Incorporation or By-Laws  of
     Sub;  (2) violate any statute, ordinance, rule, regulation, order or decree
     of any court or of any governmental or regulatory body, agency or authority
     applicable to  Parent  or  any  of  its  subsidiaries  or  by  which  their
     respective   properties  or   assets  may  be   bound,  including,  without
     limitation, any consent decrees, court orders or judgments; (3) require any
     filing with, or permit, consent or approval of, or the giving of any notice
     to any Governmental  Entity; or  (4) result in  a violation  or breach  of,
     conflict  with, constitute (with or without due  notice or lapse of time or
     both) a default (or give rise to any right of termination, cancellation  or
     acceleration)  under,  or  result in  the  creation of  any  lien, security
     interest, charge or  encumbrance upon any  of the properties  or assets  of
     Parent  or any of its  subsidiaries under, any of  the terms, conditions or
     provisions of  any note,  bond,  mortgage, indenture,  license,  franchise,
     permit,  agreement, lease or other instrument or obligation to which Parent
     or any of  its subsidiaries  is a party,  or by  which it or  any of  their
     respective  properties or assets may be bound, excluding from the foregoing
     clauses (3) and (4) filings, permits, consents, approvals and notices,  the
     absence  of which, and violations,  breaches, defaults, conflicts and liens
     which, in the aggregate,  would not have a  material adverse effect on  the
     Condition of Parent and its subsidiaries taken as a whole.
 
          (e)  Parent Reports and Financial  Statements; Accounting Records. (i)
     Since December 31, 1991, Parent has filed all forms, reports and  documents
     with the Commission required to be filed by it pursuant to the U.S. federal
     securities  laws and the rules  and regulations promulgated thereunder, and
     all forms, reports and documents filed with the Commission have complied in
     all material respects with all applicable requirements of the U.S.  federal
     securities  laws  and  the  Commission  rules  and  regulations promulgated
     thereunder. Parent  has  heretofore  delivered  to  the  Company  true  and
     complete  copies of all  forms, reports, registration  statements and other
     filings filed by the  Company with the Commission  since December 31,  1991
     (such  forms, reports, registration statements  and other filings, together
     with any amendments thereto, are sometimes collectively referred to as  the
     'Parent  Commission  Filings'). As  of their  respective dates,  the Parent
     Commission Filings did not contain any untrue statement of a material  fact
     or omit to state a material fact required to be stated therein or necessary
     to  make the statements therein, in  light of the circumstances under which
     they were made, not misleading.
 
          (ii) The  audited consolidated  financial statements  included in  the
     Parent  Commission Filings comply as to  form in all material respects with
     applicable accounting requirements  and with the  rules and regulations  of
     the  Commission  with respect  thereto,  were prepared  in  accordance with
     accounting principles generally accepted in  Israel ('Israel GAAP') (as  in
     effect  from time to time), which as applicable to Parent are substantially
     the same  as US  GAAP, applied  on a  consistent basis  (except as  may  be
     indicated  therein or in the notes or schedules thereto) and fairly present
     in all material respects the consolidated financial position of Parent  and
     its  consolidated subsidiaries as  of the dates thereof  and the results of
     their operations and changes  in cash flows,  as the case  may be, for  the
     periods  then ended. The unaudited interim financial statements included in
     the Parent
 
                                      A-17
 
<PAGE>
 
<PAGE>
     Commission Filings  were prepared  in accordance  with Israel  GAAP (as  in
     effect  from time to time) applied on  a consistent basis (except as may be
     indicated therein or in the notes or schedules thereto) and fairly  present
     the   consolidated  financial  position  of  Parent  and  its  consolidated
     subsidiaries as of the  dates thereof and the  results of their  operations
     and  changes in cash flows, as the case  may be, for the periods then ended
     subject to normal and  recurring year-end audit  adjustments and any  other
     adjustments described therein.
 
          (iii)  Parent and its  subsidiaries keep proper  accounting records in
     which all material assets and  liabilities, and all material  transactions,
     of  Parent and its subsidiaries are  recorded in conformity with applicable
     accounting principles. No part of  Parent's or any subsidiary's  accounting
     system  or records, or access thereto, is under the control of a Person who
     is not an employee of Parent or such subsidiary.
 
          (f)  Absence  of  Certain  Changes.  Except  as  disclosed  in  Parent
     Commission Filings distributed to stockholders prior to the date hereof and
     except as set forth on Schedule 3.02(f) delivered to the Company by Parent,
     since December 31, 1994, (i) there has not been any material adverse change
     in  the Condition of Parent and its subsidiaries taken as a whole; (ii) the
     businesses of Parent and its subsidiaries  have been conducted only in  the
     ordinary  course; and (iii) Parent and  its subsidiaries have not increased
     the compensation of any officer or  granted any general salary or  benefits
     increase to their employees other than in the ordinary course of business.
 
          (g)  Compliance  with  Laws.  (i)  General.  Except  with  respect  to
     regulatory matters  (which  are  covered  exclusively  by  Section  3.02(o)
     hereof) and environmental matters (which are covered exclusively by Section
     3.02(g)(ii)  below), Parent and its subsidiaries are in compliance with all
     applicable laws, regulations, orders,  judgments and decrees, except  where
     the  failure to so comply  would not have a  material adverse effect on the
     Condition of Parent and its subsidiaries taken as a whole.
 
          (ii) Environmental Matters. Except to  the extent that the  inaccuracy
     of  any  of  the  following  (or  the  circumstances  giving  rise  to such
     inaccuracy), individually  or in  the aggregate,  would not  reasonably  be
     expected  to  have a  material adverse  effect on  the Condition  of Parent
     (after taking into  account any  reserves therefor included  in the  Parent
     Commission  Filings filed  prior to  the date  hereof) or  as set  forth on
     Schedule 3.02(g)(ii) (none of which scheduled items are expected to have  a
     material adverse effect):
 
             (A)  Parent is in compliance with all applicable Environmental Laws
        and any permits, authorizations, licenses and certificates issued by any
        governmental regulatory authority  or entity  pursuant to  Environmental
        Laws;
 
             (B)  Parent  has  obtained,  or made  timely  application  for, all
        permits required for its operations under Environmental Laws;
 
             (C) there are  no uncontrolled Hazardous  Materials present in  the
        environment  or, to Parent's knowledge,  imminent threatened releases of
        Hazardous Substances into the environment at any of Parent's facilities;
        and
 
             (D) Parent has  received no  written notice that  it is  or may  be
        liable for cleanup or other costs relating to environmental matters as a
        result of (1) any Hazardous Materials in the environment at any facility
        owned  or operated by  Parent or (2) the  off-site disposal of Hazardous
        Materials generated by Parent at any of its facilities.
 
          (h) Litigation. Except as disclosed in Parent Commission Filings or as
     set forth on Schedule 3.02(h) delivered to the Company by Parent, there  is
     no  action, suit, proceeding at law or in equity, or any arbitration or any
     administrative or other  proceeding by or  before (or to  the knowledge  of
     Parent  any investigation by) any  governmental or other instrumentality or
     agency, pending, or,  to the  knowledge of Parent,  threatened, against  or
     affecting  Parent or any of its subsidiaries, or any of their properties or
     rights which if adversely determined would  be reasonably likely to have  a
     material  adverse effect  on the Condition  of Parent  and its subsidiaries
     taken as a whole. Except as disclosed in Parent Commission Filings, neither
     Parent nor any  of its subsidiaries  is subject to  any judgment, order  or
     decree  entered in any lawsuit or  proceeding which is reasonably likely to
     have a
 
                                      A-18
 
<PAGE>
 
<PAGE>
     material adverse effect  on the  Condition of Parent  and its  subsidiaries
     taken  as a whole or on the ability  of Parent or any subsidiary to conduct
     its business as presently conducted.
 
          (i) Taxes. Parent has  filed or caused to  be filed, within the  times
     and  in the manner prescribed by law, all tax returns (including authorized
     extensions) and tax reports which are required by Israel, the United States
     and any other country, state and locality  to be filed by, or with  respect
     to,  Parent or  any of  its subsidiaries.  All income,  profits, franchise,
     sales, use, occupancy,  excise and other  taxes and assessments  (including
     interest  and penalties)  payable by,  or due  from, Parent  or any  of its
     subsidiaries under the  laws of  Israel, the  United States  and any  other
     country,  state and locality  have been fully  paid or adequately disclosed
     and fully provided for in the books and financial statements of Parent  and
     its subsidiaries.
 
          (j)  Broker's or Finder's Fee. Except  for Lehman Brothers (whose fees
     and expenses as financial advisor to Parent and Sub will be paid by  Parent
     in  accordance with Parent's  agreement with such firm,  a true and correct
     copy of which has been previously  delivered to the Company by Parent),  no
     agent, broker, Person or firm acting on behalf of Parent or Sub is, or will
     be,  entitled to any fee, commission or  broker's or finder's fees from any
     of the parties hereto,  or from any Person  controlling, controlled by,  or
     under  common control  with any of  the parties hereto,  in connection with
     this Agreement or any of the transactions contemplated hereby.
 
          (k) Accounting Matters. Parent knows of no reason, within its control,
     why the  Merger will  not  be capable  of being  treated  as a  pooling  of
     interest  transaction under  APB 16. Parent  has not taken  any action that
     will prevent  the Merger  from  being recorded  as  a pooling  of  interest
     transaction under APB 16.
 
          (l)  Tax Matters.  Parent knows  of no  fact or  circumstance which is
     reasonably likely  to  cause the  Merger  to be  treated  other than  as  a
     tax-free reorganization under Section 368(a)(1)(A) of the Code by virtue of
     Section 368(a)(2)(E) of the Code.
 
          (m)  Operations  of Sub.  Sub  was formed  solely  for the  purpose of
     engaging in the transactions contemplated  hereby, has engaged in no  other
     business  activities and has conducted  its operations only as contemplated
     hereby.
 
          (n) Absence  of  Undisclosed Liabilities.  Parent  does not  have  any
     material indebtedness or material liability which is required in accordance
     with  Israel  GAAP to  be reflected  on the  consolidated balance  sheet of
     Parent as of December 31, 1994  contained in the Parent Commission  Filings
     or  otherwise  disclosed  in  the  Parent  Commission  Filings  other  than
     liabilities so  reflected  or  disclosed  or incurred  or  accrued  in  the
     ordinary   course  of  business  (including  liens  of  current  taxes  and
     assessments not in the  default) since that date.  Except as shown in  such
     balance sheet or in the notes to the financial statements contained in such
     Parent Commission Filings, neither Parent nor Sub is directly or indirectly
     liable  upon  or with  respect to  (by  discount, repurchase  agreements or
     otherwise), or obligated in any other  way to provide funds in respect  of,
     or to guarantee or assume, any material debt, obligation or dividend of any
     Person,   except  endorsements  in  the  ordinary  course  of  business  in
     connection with the deposit of items for collection.
 
          (o) Regulatory Compliance. (i) As to each drug manufactured, marketed,
     sold or licensed by Parent  in the United States for  which an NDA or  ANDA
     has  been  approved or  an IND  has been  submitted to  the FDA  and become
     effective, Parent and its subsidiaries  are in substantial compliance  with
     21  U.S.C. SSSS355  or 357  or 21 C.F.R.  Parts 312,  314 or  430 et. seq.,
     respectively, and all terms and conditions of such applications. As to each
     such drug, Parent and any relevant subsidiary, and the officers,  employees
     or agents of Parent or such subsidiary have included in the application for
     such  drug,  where  required,  the  certification  described  in  21 U.S.C.
     SS335a(k)(1) and  the list  described  in 21  U.S.C. 335a(k)(2),  and  such
     certification  and such list was  in each case true  and accurate when made
     and remained  true  and accurate  thereafter.  In addition,  Parent  is  in
     substantial   compliance  with  all  applicable  registration  and  listing
     requirements set forth in 21 U.S.C. SS360 and 21 C.F.R. Part 207.
 
                                      A-19
 
<PAGE>
 
<PAGE>
          (ii) Each article of drug manufactured and/or distributed by Parent or
     any of its subsidiaries in the United States is not adulterated within  the
     meaning  of 21 U.S.C. SS351  or misbranded within the  meaning of 21 U.S.C.
     SS352, and is not a product that is in violation of 21 U.S.C. SS355.
 
          (iii)  Except  as  disclosed  in  the  Parent  Commission  Filings  or
     otherwise  set forth in  Schedule 3.02(o), all  manufacturing operations of
     Parent and its subsidiaries  in the United States  have been and are  being
     conducted  in substantial  compliance with the  good manufacturing practice
     regulations set forth in 21 C.F.R. Parts 210 and 211.
 
          (iv) Except as  disclosed in  the Parent  Commission Filings,  neither
     Parent nor any of its subsidiaries has received any written notice that the
     FDA  has commenced, or  threatened to initiate, any  action to withdraw its
     approval or request  the recall  of any  product of  Parent or  any of  its
     subsidiaries,  or commenced, or overtly  threatened to initiate, any action
     to enjoin production at any facility of Parent or any of its subsidiaries.
 
          (v) Each drug manufactured outside the United States by Parent or  any
     of its subsidiaries is manufactured in accordance with applicable rules and
     regulations  of the jurisdiction  in which such  drug is manufactured. Each
     drug manufactured by Parent  or any of its  subsidiaries and exported  into
     another jurisdiction for distribution is imported into such jurisdiction in
     accordance  with applicable rules and  regulations of the jurisdiction into
     which such drug is imported.
 
          (vi) Neither Parent,  nor any  of its subsidiaries,  nor any  officer,
     employee  or agent of either Parent or  any of its subsidiaries has made an
     untrue statement of  a material fact  or fraudulent statement  to the  FDA,
     failed  to disclose a material fact required to be disclosed to the FDA, or
     committed an act, made a statement, or failed to make a statement that,  at
     the  time such disclosure was made, could reasonably be expected to provide
     a basis  for  the  FDA  to invoke  its  policy  respecting  'Fraud,  Untrue
     Statements  of Material Facts, Bribery,  and Illegal Gratuities', set forth
     in 56 Fed. Reg. 46191 (September 10,  1991). Neither Parent nor any of  its
     subsidiaries, nor any officer, employee or agent of either Parent or any of
     its  subsidiaries has been convicted of any crime or engaged in any conduct
     for which debarment is mandated by 21 U.S.C. SS335a(a) or authorized by  21
     U.S.C. SS335a(b).
 
                                   ARTICLE IV
                    CONDUCT OF BUSINESS; TRANSACTIONS PRIOR
                     TO CLOSING DATE; ADDITIONAL AGREEMENTS
 
     4.01 Conduct of Business of the Company. The Company agrees that, except as
expressly  permitted, required  or contemplated  by, or  otherwise described in,
this Agreement, or required by law or governmental agency or otherwise consented
to or approved in writing  by Parent, during the  period commencing on the  date
hereof and ending on the Closing Date:
 
          (a)  The  Company  and each  of  its subsidiaries  will  conduct their
     respective operations  in all  material respects  only according  to  their
     ordinary and usual course of business and will use their reasonable efforts
     to  preserve intact their respective business organizations, keep available
     the services of their directors,  officers and employees, preserve in  full
     force  and  effect all  material licenses  and approvals  held by  them and
     maintain satisfactory relationships with, suppliers, distributors,  clients
     and others having material business relationships with them;
 
          (b)  Neither the Company nor any of its subsidiaries will (i) make any
     change in or amendment to its Certificate of Incorporation or By-Laws; (ii)
     issue or sell any shares of its capital stock or share capital (other  than
     in  connection with (A) the Company's Stockholder Dividend Reinvestment and
     Stock Purchase Plan or (B) the  exercise of options granted under  employee
     and directors' stock option plans outstanding on the date hereof) or any of
     its other securities, or issue any securities convertible into, or options,
     warrants  or  rights  to  purchase  or  subscribe  to,  or  enter  into any
     arrangement or contract with respect to the issuance or sale of, any shares
     of its capital  stock or any  of its  other securities, or  make any  other
     changes  in its capital structure; (iii)  declare, pay or make any dividend
     or other distribution or payment with respect to, or split, combine, redeem
     or reclassify, any shares of its capital stock or share capital other  than
     in accordance with
 
                                      A-20
 
<PAGE>
 
<PAGE>
     the  Company's  Restricted  Stock  Purchase  Plan  or  Shareholder Dividend
     Reinvestment and  Stock Purchase  Plan;  (iv) enter  into any  contract  or
     commitment  with respect  to capital  expenditures in  excess of  those set
     forth in Schedule 4.01(b) delivered to  Parent by the Company or in  excess
     of $100,000, individually, or $200,000, in the aggregate, or enter into any
     other  material contracts or  commitments except contracts  in the ordinary
     course of  business; (v)  acquire  assets (other  than as  contemplated  by
     clause  (iv) above), other than  in the ordinary course  of business, in an
     amount in excess of $100,000, individually, or $200,000, in the  aggregate,
     or  dispose of (including by way of sale, lease or encumbrance), other than
     in the ordinary course of business, a material amount of assets or  release
     or  relinquish any material rights under any material contract; (vi) except
     as contemplated  by  this Agreement,  amend  any employee  or  non-employee
     benefit  plan  or  program,  employment  agreement,  license  agreement  or
     retirement agreement, or pay any  bonus or contingent compensation,  except
     in  each  case in  the  ordinary course  of  business consistent  with past
     practice prior to the date of this Agreement; (vii) incur any  indebtedness
     for  borrowed money (other  than by drawing  under current revolving credit
     agreements (as such agreements are in effect on the date hereof and without
     giving effect to any waivers of any of the provisions of such  agreements))
     or  guarantee any such indebtedness or issue or sell any debt securities or
     warrants or rights to acquire any debt securities of the Company or any  of
     its  subsidiaries or guarantee any debt securities of others; (viii) agree,
     in writing or otherwise,  to take any of  the foregoing actions; (ix)  make
     any  material  change in  its method  of accounting  or record  keeping not
     otherwise required  by US  GAAP; or  (x)  agree to  the settlement  of  any
     material  litigation for  any amounts  in excess  of those  reserved on the
     Company's books and records;
 
          (c) The  Company will  not, nor  will the  Company permit  any of  its
     subsidiaries  to, purchase or acquire, or offer to purchase or acquire, any
     shares of its capital  stock, other than in  connection with the  Company's
     Restricted  Stock Purchase  Plan and Stockholder  Dividend Reinvestment and
     Stock Purchase Plan; and
 
          (d) The Company will  deliver to Parent all  of Company's monthly  and
     quarterly, if any, financial statements for periods and dates subsequent to
     March  31, 1995, as soon as practicable after the same are available to the
     Company.
 
Any action  consented  to  under  this  Section 4.01  shall  not  be  deemed  to
constitute  a  breach  of  any  representation  or  warranty  contained  in this
Agreement.
 
     4.02 Access to Information Concerning Business and Records. (a) During  the
period commencing on the date hereof and ending on the Closing Date, the Company
shall,   upon  reasonable  notice,  afford   to  Parent  and  Parent's  counsel,
accountants and  other  authorized  representatives,  reasonable  access  during
normal  business hours to the  properties, books and records  of the Company and
its subsidiaries  in order  that they  may  have the  opportunity to  make  such
investigations  as  they shall  desire of  the  affairs of  the Company  and its
subsidiaries; such investigation shall not, however, affect the  representations
and  warranties made in this Agreement. The Company agrees to cause its officers
and employees to furnish such additional financial and operating data and  other
information  and respond  to such  inquiries as Parent  shall from  time to time
request.
 
     (b) During  the period  commencing on  the date  hereof and  ending on  the
Closing  Date, Parent shall,  upon reasonable notice, afford  to the Company and
the  Company's  counsel,  accountants  and  other  authorized   representatives,
reasonable  access during  normal business  hours to  the properties,  books and
records of  Parent  and  its  subsidiaries  in order  that  they  may  have  the
opportunity  to make such investigations as they  shall desire of the affairs of
Parent and its subsidiaries; such  investigation shall not, however, affect  the
representations  and warranties made  in this Agreement.  Parent agrees to cause
its officers and employees  to furnish such  additional financial and  operating
data  and other information and  respond to such inquiries  as the Company shall
from time to time request.
 
     4.03 Confidentiality.  Information  obtained  by  Parent  and  the  Company
pursuant   to  this  Agreement  shall  be  subject  to  the  provisions  of  the
Confidentiality Agreement between the Company and Parent.
 
     4.04 Registration  Statement/Proxy Statement;  Listing  on Tel  Aviv  Stock
Exchange.  (a) As promptly as practicable after the execution of this Agreement,
the Company and Parent  shall prepare and file  with the Commission  preliminary
proxy    materials    which    shall    constitute    the    preliminary   Proxy
 
                                      A-21
 
<PAGE>
 
<PAGE>
Statement and a preliminary prospectus with  respect to the Ordinary Shares  and
ADSs  to be  issued in  connection with the  Merger. As  promptly as practicable
after comments are received from the Commission with respect to the  preliminary
proxy  materials  and after  the furnishing  by  the Company  and Parent  of all
information required  to be  contained therein  (including, without  limitation,
financial  statements and supporting  schedules and certificates  and reports of
independent public accountants), the Company shall file with the Commission  the
definitive  Proxy  Statement  and  Parent shall  file  with  the  Commission the
definitive Proxy Statement and the Registration Statement, which Proxy Statement
and Registration Statement shall each comply  in all material respects with  the
applicable  requirements of the  Exchange Act and  Securities Act, respectively,
and the applicable rules  and regulations of  the Commission thereunder.  Parent
and the Company shall use their best efforts to cause the Registration Statement
to  become effective  as soon  thereafter as  practicable. The  definitive Proxy
Statement shall  contain the  opinion of  Goldman  Sachs &  Co. referred  to  in
Section  3.01(p) of this Agreement, provided  that such opinion shall be brought
down to and dated, a date not more  than two business days prior to the date  of
the Proxy Statement.
 
     (b)  The  Company shall  cause  the Proxy  Statement  to be  mailed  to the
stockholders of the Company and, if  necessary, after the Proxy Statement  shall
have  been so mailed,  promptly circulate amended,  supplemental or supplemented
proxy material and, if required in connection therewith, resolicit proxies.
 
     (c) Each of Parent and Sub, on the one hand, and the Company, on the  other
hand,  warrants to the other that the information provided and to be provided by
Parent  and  Sub  and  the  Company,  respectively,  for  use  in  each  of  the
Registration   Statement,  on  the  date   the  Registration  Statement  becomes
effective, and the  Proxy Statement, on  the date the  Proxy Statement is  filed
with  the  Commission,  on  the  date  it  is  first  mailed  to  the  Company's
stockholders and on the date of the Special Meeting (as defined in Section  4.06
below)  shall not  contain any untrue  statement of  a material fact  or omit to
state any material fact  necessary in order to  make the statements therein,  in
light  of the circumstances under which they  were made, not misleading. Each of
Parent and Sub, on the one hand, and the Company, on the other, shall notify the
other parties promptly of the receipt of  any comments by the Commission and  of
any  request by the Commission for  amendments or supplements to the preliminary
Proxy Statement,  the  Proxy Statement  or  the Registration  Statement  or  for
additional  information,  and  shall  supply  one  another  with  copies  of all
correspondence with the Commission with respect  to any of the foregoing. If  at
any time prior to the Special Meeting, any event should occur relating to Parent
or  Sub (or  any of  their respective  affiliates, directors  or officers) which
should be described in an amendment or supplement to the Proxy Statement or  the
Registration Statement, Parent shall promptly inform the Company. If at any time
prior  to the Special Meeting,  any event should occur  relating to the Company,
its subsidiaries or any  of their respective  affiliates, directors or  officers
which  should be described in an amendment  or supplement to the Proxy Statement
or the  Registration  Statement,  the  Company  shall  promptly  inform  Parent.
Whenever  any  event  occurs  which  should  be  described  in  an  amendment or
supplement to the Proxy Statement or the Registration Statement, Parent and  the
Company  shall, upon learning of such  event, cooperate with each other promptly
to file and clear with the Commission and, if applicable, mail such amendment or
supplement to the stockholders of the Company.
 
     (d) Each of Parent and Sub, on the one hand, and the Company, on the  other
hand,  warrants to the other that all information concerning the Parent, Sub and
Parent's other subsidiaries, and the Company and its subsidiaries, respectively,
to be supplied expressly for inclusion in the listing application to be prepared
for and filed  with the TASE  with respect to  Ordinary Shares to  be issued  in
connection with the transactions contemplated hereby and any supplements thereto
and  any other  materials or  documents issued  to stockholders  or employees of
Parent on or after the  date hereof will not contain  any untrue statement of  a
material  fact or omit  to state a  material fact required  to be stated therein
necessary to make the  statements therein, in light  of the circumstances  under
which they were made, not misleading.
 
     (e) Parent and the Company shall make all necessary filings with respect to
the  Merger under  the Securities  Act and  the Exchange  Act and  the rules and
regulations thereunder and under applicable
 
                                      A-22
 
<PAGE>
 
<PAGE>
blue sky or similar  laws and shall  use their best  efforts to obtain  required
approvals and clearances with respect thereto.
 
     4.05 Employee Benefits. (a) Parent shall cause the Surviving Corporation to
adopt  a severance plan providing  for payment to each  employee of the Company,
whose tenure  and conditions  of  employment are  not  covered by  a  collective
bargaining  agreement, and whose employment is  terminated within one year after
the Effective Time a severance benefit in cash in an amount equal to: (i) in the
case of Vice  Presidents and Assistant  Vice Presidents of  the Company,  twelve
(12)  months base salary, payable in equal monthly installments, and (ii) in the
case of  other non-union  employees,  such employee's  regular weekly  base  pay
multiplied  by the number of years of  employment such employee has had with the
Company up to ten (10)  years of employment, plus  two times such weekly  salary
multiplied by the number of years of such employment beyond the tenth year (such
payment  to be paid  on a weekly basis  in an amount  not exceeding such regular
weekly base pay, and reduced by  any applicable withholding and payroll  taxes);
provided,  however,  that the  Surviving Corporation  shall  be free  to include
customary provisions  in  such  severance plan  including,  without  limitation,
provisions  which preclude payment in  the event of a  termination for cause and
payment as a  result of  inter-plant transfers  among the  Company's New  Jersey
facilities.  Any such  employee whose employment  is terminated  after the first
anniversary of  the Effective  Time  shall be  entitled  to the  same  severance
benefits  as are payable  to other non-union employees  of Parent's U.S. generic
drug subsidiary.
 
     (b) At the Effective Time, subject  to applicable law, all of the  Employee
Benefit  Plans as of the  Closing Date, other than  those involving stock of the
Company ('Current Benefits') and all  employment agreements between the  Company
and  any of its employees  in effect as of the  Closing Date shall continue, and
for not less than one year from and after the Closing Date, Parent shall provide
for the employees of the Surviving Corporation to continue to participate in the
Current Benefits and to be provided  aggregate benefits thereunder that are  not
less than those provided thereunder during the Company's fiscal year ended March
31,  1995. Nothing herein shall preclude any change effected after such one-year
period on a prospective basis  in any Employee Benefit  Plan or Pension Plan  or
prohibit  Parent or  the Surviving  Corporation from  terminating any particular
Employee Benefit  Plan following  such  one-year period,  provided that  to  the
extent  Parent or the Surviving Corporation terminates any Employee Benefit Plan
after the Effective Time, and any U.S. generic drug subsidiary of Parent has  in
place  a  benefit  plan providing  benefits  of  the same  general  type  as the
terminated  Employee  Benefit  Plan  to  its  similarly  situated  subsidiaries'
employees,  Parent  shall  thereafter  permit  the  employees  of  the Surviving
Corporation to participate in such employee benefit plan of its U.S.  subsidiary
or a similar plan.
 
     4.06 Company Stockholder Approval; Recommendation. Subject to Section 4.17,
the  Company, acting through  its Board of  Directors, shall (i)  call a special
meeting of the holders of  Company Common Stock for  the purpose of voting  upon
this  Agreement and the Merger  (the 'Special Meeting') and  (ii) include in the
Proxy Statement the  recommendation of its  Board of Directors  that holders  of
Company Common Stock approve and adopt this Agreement and approve the Merger.
 
     4.07  Stock Options. The Company shall take such action as may be permitted
under the Stock Option Plans to effect the actions described in Section 2.05 and
shall  comply  with  all  requirements  regarding  income  tax  withholding   in
connection  therewith. In addition  to the foregoing, the  Company will take all
steps necessary to obtain and  deliver to Parent, at  or prior to the  Effective
Time,  the written consent of each optionee  under the Stock Option Plans to the
actions described  in Section  2.05 hereof  and shall  take whatever  action  is
reasonably  required to satisfy Parent that no holder of options or rights under
the Stock  Option Plans  will have  any right  to acquire  any interest  in  the
Company  or  Parent as  a result  of the  exercise  of options  on or  after the
Effective Time. The  Company shall  not make any  further grants  of options  or
rights  of  any nature  under  the Stock  Option Plans  after  the date  of this
Agreement, nor shall the Company's Board of Directors, Compensation Committee or
Stock Option Committee take any action that is inconsistent with Section 2.05 or
this Section 4.07 of this Agreement.
 
     4.08 Letters of the Company's Accountants.  The Company shall use its  best
efforts  to cause  to be  delivered to  Parent a  letter of  Ernst &  Young, the
Company's independent auditors, dated a date within
 
                                      A-23
 
<PAGE>
 
<PAGE>
two business days before the date of the Proxy Statement and a second bring-down
letter, dated a date within two business days before the Effective Time, in each
case addressed  to Parent,  in  form and  substance reasonably  satisfactory  to
Parent and customary in scope and substance for letters delivered by independent
public  accountants in  connection with  registration statements  similar to the
Registration Statement. The accountants' letters shall not consider any  changes
arising  from  the  announcement or  consummation  of  the Merger  or  the other
transactions contemplated by this Agreement.
 
     4.09 Letters of Parent's Accountants. Parent shall use its best efforts  to
cause to be delivered to the Company a letter of Kesselman & Kesselman, Parent's
independent  auditors, dated a day  within two business days  before the date on
which the Registration Statement shall become effective and a second  bring-down
letter, dated a date within two business days before the Effective Time, in each
case  addressed to the Company, in form and substance reasonably satisfactory to
the Company  and customary  in  scope and  substance  for letters  delivered  by
independent  public  accountants  in  connection  with  registration  statements
similar to  the  Registration  Statement. The  accountants'  letters  shall  not
consider any changes arising from the announcement or consummation of the Merger
or the other transactions contemplated by this Agreement.
 
     4.10 Notices of Certain Events. Each party hereto shall promptly notify the
other parties of:
 
          (a)  any notice or  other communication from  any Person alleging that
     the consent of such  Person is or  may be required  in connection with  the
     transactions contemplated by this Agreement;
 
          (b)  any notice or other communication from any Governmental Entity in
     connection with the transactions contemplated by this Agreement;
 
          (c)  any  actions,  suits,   claims,  investigations  or   proceedings
     commenced  or, to the best of its knowledge threatened against, relating to
     or involving or otherwise affecting any  of Parent, Sub or the Company,  as
     the  case may be, or  any of their respective  subsidiaries which relate to
     the consummation of the transactions contemplated by this Agreement; and
 
          (d) such party's obtaining knowledge of the occurrence, or failure  to
     occur,  of any event which occurrence or failure to occur will be likely to
     cause (A) any representation or warranty contained in this Agreement to  be
     untrue  and inaccurate in any material respect, or (B) any material failure
     of any party to comply with or satisfy any covenant, condition or agreement
     to be complied  with or  satisfied by  it under  this Agreement;  provided,
     however,  that  no  such  notification  shall  affect  the representations,
     warranties  or  obligations  of  the  parties  or  the  conditions  to  the
     obligations of the parties hereunder.
 
     4.11  Tel Aviv Stock Exchange Listing. Parent shall make application to the
TASE for, and  use its best  efforts to  obtain, the listing  of the  additional
Ordinary Shares to be issued pursuant to this Agreement on the TASE.
 
     4.12  NASDAQ/NMS Admission. Parent shall use  its best efforts to cause the
ADSs issued pursuant to the Merger to be admitted for trading on the NASDAQ/NMS,
subject to official notice of issuance.
 
     4.13 HSR Act. The  Company and Parent shall,  as soon as practicable  after
the date of this Agreement, file Notification and Report Forms under the HSR Act
with  the Federal Trade Commission (the 'FTC') and the Antitrust Division of the
Department of  Justice  (the 'Antitrust  Division')  and shall  use  their  best
efforts to respond as promptly as practicable to all inquiries received from the
FTC or the Antitrust Division for additional information or documentation.
 
     4.14  Indemnification;  Officers' and  Directors'  Insurance. (a)  From and
after the Effective Time, Parent and the Surviving Corporation shall  indemnify,
defend  and hold harmless each  person who was, is now,  or who becomes prior to
the Effective  Time,  an officer,  director  or  employee of  the  Company  (the
'Indemnified   Parties')   against  all   losses,  expenses,   claims,  damages,
liabilities, costs, expenses, judgments or  amounts that are paid in  settlement
with  the  approval  of  the  indemnifying party  (which  approval  will  not be
unreasonably withheld)  arising out  of the  transactions contemplated  by  this
Agreement  to the fullest extent provided for under the Company's Certificate of
Incorporation and By Laws  as in effect  as of the date  hereof or permitted  or
required  by  applicable law,  including without  limitation the  advancement of
expenses. Parent agrees  that all  rights to indemnification  existing in  favor
 
                                      A-24
 
<PAGE>
 
<PAGE>
of  the  directors, officers  or employees  of  the Company  as provided  in the
Company's Certificate of Incorporation or By-Laws,  as in effect as of the  date
hereof,  with respect  to matters  occurring through  the Effective  Time, shall
survive the Merger and shall continue in  full force and effect for a period  of
not  less than six years  from the Effective Time,  and Parent hereby guarantees
the due and prompt  performance in full of  such indemnification obligations  of
the  Surviving Corporation. Parent agrees  to use its best  efforts to cause the
Surviving Corporation to maintain in effect for not less than three years  after
the  Effective Time the  current policies of  directors' and officers' liability
insurance maintained by the Company with  respect to matters occurring prior  to
the  Effective Time; provided,  however, that (i)  the Surviving Corporation may
substitute therefor  policies  of at  least  the same  coverage  (with  carriers
comparable  to the Company's existing  carriers) containing terms and conditions
which are no less advantageous to the Indemnified Parties and (ii) the Surviving
Corporation shall not be required to pay a premium at a rate for such  insurance
in  excess of 150%  of the annual  premium rate represented  by the last premium
paid prior to the date hereof, but in such case shall purchase as much  coverage
as  possible for  such amount and  (iii) any  or all of  the Indemnified Parties
shall have  the right  to provide  funds to  the Surviving  Corporation to  fund
premiums to the extent they exceed such 150% level.
 
     (b)  In  the  event  that any  action,  suit,  proceeding  or investigation
relating hereto  or  to  the  transactions contemplated  by  this  Agreement  is
commenced,  whether before or after the Effective Time, the parties hereto agree
to cooperate and use their respective best efforts to vigorously defend  against
and respond thereto.
 
     (c)  The provisions of this  Section 4.14 are intended  for the benefit of,
and shall be enforceable  by, each Indemnified  Party and his  or her heirs  and
representatives.
 
     4.15  Best Efforts. Each  of the Company,  Parent and Sub  shall, and shall
cause each  of  their  respective  subsidiaries  to,  cooperate  and  use  their
respective  best efforts to take, or cause  to be taken, all appropriate action,
and to make, or  cause to be  made, all filings  necessary, proper or  advisable
under  applicable  laws and  regulations to  consummate  and make  effective the
transactions contemplated  by  this Agreement,  including,  without  limitation,
their  respective  best  efforts  to  obtain, prior  to  the  Closing  Date, all
licenses,  permits,  consents,  approvals,  authorizations,  qualifications  and
orders   of  governmental  authorities   (including,  without  limitation,  ISRA
Clearance) and parties to  contracts with the Company  and its subsidiaries  and
Parent   and  its  subsidiaries  as  are   necessary  for  consummation  of  the
transactions contemplated by this Agreement and to fulfill the conditions to the
Merger.
 
     4.16 Rule 145. Schedule 4.16 delivered by the Company to Parent  identifies
'Affiliates'  of the Company for purposes of  Rule 145 under the Securities Act.
The Company shall  cause each  such Person  to deliver  to Parent  prior to  the
Closing  Date a written agreement substantially in the form of Exhibit A hereto,
or in the case  of Harold Snyder  and Beatrice Snyder  and certain trusts  which
they  have established a written agreement  substantially in the form of Exhibit
A-1 hereto (each an 'Affiliate Agreement').
 
     4.17 No Solicitation. (a) The Company shall not, nor shall it permit any of
its subsidiaries to, nor  shall it authorize or  permit any officer or  director
of,  or any investment  banker, attorney or other  advisor or representative of,
the Company or any of its subsidiaries to, directly or indirectly, (i)  solicit,
initiate   or  encourage  the  submission  of  any  Takeover  Proposal  or  (ii)
participate in  any discussions  or negotiations  regarding, or  furnish to  any
Person  any information with respect to, or  take any other action to facilitate
any inquiries or the making of any proposal that constitutes, or may  reasonably
be  expected to lead to, any Takeover  Proposal; provided, however, that, to the
extent required by the  fiduciary obligations of the  Board of Directors of  the
Company,  as determined in good faith by  the Board of Directors after reviewing
the advice  of  outside  counsel,  the  Company  may,  (A)  in  response  to  an
unsolicited request therefor, furnish information with respect to the Company to
any  Person pursuant to a customary  confidentiality agreement (as determined by
the Company's outside  counsel) and discuss  (1) such information  (but not  the
terms  of any possible Takeover Proposal) and (2) the terms of this Section 4.17
with such Person and  (B) upon receipt  by the Company  of a Takeover  Proposal,
following delivery to Parent of the notice required pursuant to Section 4.17(c),
participate  in discussions  or negotiations  regarding such  Takeover Proposal.
Without limiting  the foregoing,  it is  understood that  any violation  of  the
restrictions   set  forth   in  the  preceding   sentence  by   any  officer  or
 
                                      A-25
 
<PAGE>
 
<PAGE>
director of the  Company or any  of its subsidiaries  or any investment  banker,
attorney  or  other advisor  or  representative of  the  Company or  any  of its
subsidiaries, whether or not such Person is  purporting to act on behalf of  the
Company  or any of its subsidiaries or otherwise, shall be deemed to be a breach
of this  Section  4.17(a)  by  the Company.  For  purposes  of  this  Agreement,
'Takeover   Proposal'  means  any  proposal  for  a  merger  or  other  business
combination involving the  Company or any  proposal or offer  to acquire in  any
manner,  directly or indirectly, an equity interest in, not less than 20% of the
outstanding voting securities of,  or assets representing not  less than 20%  of
the  annual revenues of the Company, other than the transactions contemplated by
this Agreement.
 
     (b) Neither the Board of Directors of the Company nor any committee thereof
shall (i) withdraw  or modify, or  propose to  withdraw or modify,  in a  manner
adverse  to  Parent or  Sub, the  approval  or recommendation  by such  Board of
Directors or any such committee of this Agreement or the Merger, (ii) approve or
recommend, or propose to  approve or recommend, any  Takeover Proposal or  (iii)
enter  into any agreement with respect to any Takeover Proposal. Notwithstanding
the foregoing, in the  event the Board  of Directors of  the Company receives  a
Takeover  Proposal  that,  in  the exercise  of  its  fiduciary  obligations (as
determined in good faith by the Board of Directors after reviewing the advice of
outside counsel),  it  determines  to  be a  Superior  Proposal,  the  Board  of
Directors  may  (subject  to the  following  sentences) withdraw  or  modify its
approval or recommendation of this Agreement or the Merger, approve or recommend
any such  Superior  Proposal, enter  into  an  agreement with  respect  to  such
Superior  Proposal or terminate this  Agreement, in each case  at any time after
the second business day following Parent's receipt of written notice (a  'Notice
of  Superior Proposal') advising Parent that the Board of Directors has received
a Superior  Proposal,  specifying the  material  terms and  conditions  of  such
Superior  Proposal and identifying the Person  making such Superior Proposal. In
addition, if the Company proposes to enter into an agreement with respect to any
Takeover Proposal,  it  shall concurrently  with  taking any  of  the  foregoing
actions  pay, or cause to be paid, to  Parent the Termination Fee (as defined in
Section 7.01(c)). For purposes  of this Agreement,  a 'Superior Proposal'  means
any  bona fide Takeover  Proposal on terms  which the Board  of Directors of the
Company determines in its  good faith reasonable  judgment (after reviewing  the
advice  of a financial  advisor of nationally recognized  reputation) to be more
favorable to the Company's stockholders than the Merger.
 
     (c) In addition to  the obligations of the  Company set forth in  paragraph
(b) above, the Company shall promptly advise Parent orally and in writing of any
request for information or of any Takeover Proposal, or any inquiry with respect
to  or which could reasonably be expected  to lead to any Takeover Proposal, the
material terms and conditions of such request, Takeover Proposal or inquiry, and
the identity of  the Person making  any such Takeover  Proposal or inquiry.  The
Company  shall use its best efforts to  keep Parent fully informed of the status
and details of any such request, Takeover Proposal or inquiry.
 
     4.18  Post  Merger  Restructurings.  Parent  shall  indemnify  the   former
shareholders  of the Company who held  Company Common Stock immediately prior to
the Effective Time  from, and hold  them harmless against,  any federal,  state,
local  and foreign  tax liability that  they may incur  if Parent or  any of its
affiliates  effects   any  merger,   consolidation,  reorganization,   issuance,
transfer,  assignment, conveyance, disposition or other transaction with respect
to the  Surviving  Corporation,  its  capital stock  or  its  assets  after  the
Effective Time, which, without regard to Section 367 of the Code, results in the
Merger being treated other than as a tax-free reorganization under the Code.
 
     4.19  Voting of Shares  Subject to Proxy. Parent  shall exercise its rights
under the  Irrevocable Proxy  and Termination  Rights Agreement  dated the  date
hereof (the 'Proxy') to vote the Shares (as defined in the Proxy) at any meeting
or  in connection with any written consent  of the Company's stockholders (i) in
favor of the Merger, and (ii) in favor of this Agreement.
 
     4.20 Parent Shareholder Meeting.  Parent shall hold  the annual meeting  of
its  shareholders as  soon as  practicable after the  Effective Time,  but in no
event no later than October 30, 1996,  at which meeting the Snyder family  shall
be  entitled  under the  terms of  Parent's Articles  of Association  to appoint
Beatrice Snyder as a director of Parent by virtue of their holding in excess  of
4%  of Parent's outstanding share capital as of the record date of such meeting.
The Board of Directors of Parent has adopted a resolution (a) nominating  Harold
Snyder for election at such annual meeting as an
 
                                      A-26
 
<PAGE>
 
<PAGE>
Additional  Director of Parent for a term  of three years, (b) recommending that
upon his election to the Board, Harold Snyder shall be designated as a member of
the Executive Committee of Parent's Board  of Directors and (c) recommending  to
the  Board of Directors as reconstituted after  each of the following two annual
meetings of shareholders to continue to designate Mr. Snyder as a member of  the
Executive Committee while he continues to serve on the Board.
 
     4.21  Dispositions  Contrary to  Pooling. Parent  shall  not (A)  after the
Effective Time make any disposition of  the assets of the Surviving  Corporation
or  any equity  interest in  the Surviving  Corporation which  would prevent the
Merger from being recorded as a pooling of interest transaction under APB 16  or
(B)  prior to the third anniversary of  the Effective Time, make any disposition
of the  assets of  the Surviving  Corporation  or any  equity interests  in  the
Surviving  Corporation that  would cause  any recognition  of gain  under a gain
recognition agreement  entered  into with  the  Internal Revenue  Service  under
Section  367(a)  of  the Code  and  Section  1.367(a)-3T of  the  U.S. Temporary
Treasury Income Tax Regulations by any former shareholder of the Company who  is
a    'five   percent   transferee   shareholder'    (as   defined   in   Section
1.367(a)-3T(c)(6)(ii)),   except    a   disposition    described   in    Section
1.367(a)-3T(g)(7)  as  to  which  Parent provides  the  five  percent transferee
shareholders, on  a  timely  basis,  with notice  of  the  disposition  and  all
information they require in order to comply with the requirements of subdivision
(i)  of that  section. Parent  shall (i)  cause the  Company to  comply with the
reporting  requirements  of  Section  1.367(a)-3T(c)(4)  and  (ii)  provide  the
five-percent  transferee shareholders with all information they require in order
to comply with the provisions  of paragraphs (5), (6)  and (7)(ii) and (iii)  of
Section 1.367(a)-3T(g).
 
     If  prior to the third anniversary of the Effective Time, the U.S. Treasury
or the Internal  Revenue Service has  not officially (in  a published  statement
upon which taxpayers may rely) eliminated the retroactive imposition of interest
charges  on tax recognized with  respect to shares which  were covered by a gain
recognition agreement to the extent sold prior  to the date of a disposition  of
the  type described in clause (B) above or otherwise caused the gain recognition
agreement in respect of shares so sold to  become null and void as to such  sold
shares, and if prior to such third anniversary, all such five percent transferee
shareholders  shall together have  diligently sought to  obtain a private letter
ruling  from  the   Internal  Revenue   Service  providing   relief  from   such
retroactively   imposed  interest   charges,  permitting   Parent's  counsel  to
participate fully in the preparation and prosecution of such letter ruling,  and
they  shall have  failed to  obtain such  a ruling,  then the  three year period
described in clause (B) above shall be  extended to the earlier to occur of  (x)
the  fifth anniversary of the Effective Time or  (y) the date on which relief of
the type described in this sentence shall have been obtained.
 
     4.22 Dividend  Reinvestment Plan.  As soon  as practicable  after the  date
hereof  (but in no event later than March  1, 1996), the Company shall amend the
Stockholder Dividend  Reinvestment  and Stock  Purchase  Plan to  terminate  the
supplemental payment investment option offered thereunder.
 
                                   ARTICLE V
                         CONDITIONS PRECEDENT TO MERGER
 
     5.01  Conditions Precedent to  Obligations of Parent,  Sub and the Company.
The respective obligations of Parent and Sub, on the one hand, and the  Company,
on  the other  hand, to  effect the  Merger are  subject to  the satisfaction or
waiver (subject to applicable law) at or prior to the Effective Time of each  of
the following conditions:
 
          (a)  Approval of Stockholders. This  Agreement, the Merger and related
     transactions shall have been approved and adopted by the requisite vote  or
     consent  of the stockholders  of the Company  in accordance with applicable
     law and the Company's Certificate of Incorporation and By-Laws.
 
          (b) HSR Act. Any waiting period (and any extension thereof) under  the
     HSR Act applicable to the Merger shall have expired or been terminated.
 
          (c)  Litigation. No preliminary or permanent injunction or other order
     shall have been issued  by any court or  by any governmental or  regulatory
     agency,  body  or  authority  which  enjoins,  restrains  or  prohibits the
     transactions  contemplated  hereby,  including  the  consummation  of   the
 
                                      A-27
 
<PAGE>
 
<PAGE>
     Merger  or has  the effect  of making  the Merger  illegal and  which is in
     effect at the Effective Time (each  party agreeing to use its best  efforts
     to have any such injunction or order lifted).
 
          (d) Statutes. No statute, rule, regulation, executive order, decree or
     order of any kind shall have been enacted, entered, promulgated or enforced
     by  any court or governmental authority which prohibits the consummation of
     the Merger or has the effect of making the Merger illegal.
 
          (e) Tel  Aviv Stock  Exchange  Listing. The  TASE shall  have  granted
     Parent's  application for the listing of  the additional Ordinary Shares to
     be issued in connection with the Merger.
 
          (f) NASDAQ/NMS  Listing. The  ADSs  issuable to  Company  stockholders
     pursuant  to this  Agreement shall  have been  admitted for  trading on the
     NASDAQ/NMS upon official notice of issuance.
 
          (g)  Effectiveness   of  Registration   Statement.  The   Registration
     Statement  shall have become effective in accordance with the provisions of
     the Securities  Act and  shall not  be the  subject of  any stop  order  or
     proceedings seeking a stop order.
 
          (h)  Consent  of Controller  of  Foreign Currency.  The  Controller of
     Foreign Currency of the Bank of Israel shall have consented to the  Merger,
     the  issuance of the Ordinary Shares  in connection therewith and the other
     transactions contemplated by this Agreement.
 
          (i) Consents. Consents  from government bodies  and authorities  which
     are  required in order to consummate  the Merger and the other transactions
     contemplated hereby and the failure to  obtain which would have a  material
     adverse  effect on the Condition of Parent  and its subsidiaries taken as a
     whole after giving  effect to  the Merger  (including, without  limitation,
     consent  under the  Insurance Holding Company  Systems law of  the State of
     Hawaii) shall have been obtained.
 
          (j) Tax  Opinion.  The Company  shall  have received  the  opinion  of
     Proskauer  Rose Goetz & Mendelsohn LLP, counsel to the Company, and each of
     Parent and the Company  shall have received the  opinion of Willkie Farr  &
     Gallagher,  counsel to Parent, each  to the effect that  the Merger will be
     treated for United States federal  income tax purposes as a  reorganization
     within  the meaning of  Section 368(a) of  the Code, and  that the Company,
     Parent and  Sub will  each be  a party  to that  reorganization within  the
     meaning  of Section 368(b) of the Code, dated  on or about the date that is
     two business days prior to the date the Proxy Statement is first mailed  to
     stockholders  of  the  Company,  which opinion  shall  have  not  have been
     withdrawn or modified in any material respect.
 
          (k) Market Events. There shall not have occurred and be continuing any
     general suspension or limitation of trading  in the Ordinary Shares or  the
     ADSs  (exclusive, however, of any  temporary suspension pending and ensuing
     public announcement) or in securities generally on the NASDAQ/NMS.
 
          (l) Employment Agreements. Each  of the Persons  named on Exhibit  B-1
     shall  have signed  an Employment  Agreement substantially  in the  form of
     Exhibit B-2 hereto.
 
     5.02 Conditions Precedent to Obligations of Parent and Sub. The obligations
of Parent and Sub to effect the  Merger are also subject to the satisfaction  or
waiver, at or prior to the Effective Time, of each of the following conditions.
 
          (a)  Accuracy of  Representations and  Warranties. All representations
     and warranties of the Company contained herein shall be true and correct in
     all material respects as of the date  hereof and at and as of the  Closing,
     with the same force and effect as though made on and as of the Closing Date
     unless  the failure of  such representations and warranties  to be true and
     correct  in  all  material  respects  does  not,  individually  or  in  the
     aggregate, materially and adversely affect the value of the Company and the
     Subsidiaries  taken as a  whole, and Parent  and Sub shall  have received a
     certificate to this effect  from the chief executive  officer and a  senior
     financial officer of the Company.
 
          (b) Performance by Company. Except as otherwise agreed in writing, the
     Company  shall have performed in all  material respects all obligations and
     agreements, and complied in  all material respects  with all covenants  and
     conditions,    contained   in   this   Agreement   to   be   performed   or
 
                                      A-28
 
<PAGE>
 
<PAGE>
     complied with by it  on or prior  to the Closing Date,  and Parent and  Sub
     shall  have received a certificate to  this effect from the chief executive
     officer and a senior financial officer of the Company.
 
          (c) Affiliate Agreements.  Each Person  named in  Schedule 4.16  shall
     have executed and delivered to the Company an Affiliate Agreement.
 
          (d)  Legal Opinion. Parent  shall have received  an opinion, dated the
     Closing Date, of Proskauer  Rose Goetz &  Mendelsohn LLP, substantially  to
     the effect set forth in Exhibit C hereto.
 
          (e)  Accountants'  Letters. Parent  shall have  received from  Ernst &
     Young the letters referred to in Section 4.08.
 
          (f) Accounting Treatment.  Parent shall  have received  an opinion  in
     form  and substance satisfactory to it from Kesselman & Kesselman dated the
     Closing  Date,  stating  that,  in  its  opinion,  there  is  no  fact   or
     circumstance  concerning Parent or Sub which  would cause the Merger not to
     be recorded for accounting  purposes as a pooling  of interests under  both
     Israel GAAP and US GAAP.
 
          (g) ISRA. The Company shall have obtained ISRA Clearance.
 
          (h)  Israeli  Securities Compliance.  Parent  shall have  received the
     required permit from the Israeli Securities Authority to publish the  Proxy
     Statement  or  shall have  obtained an  exemption  from the  requirement to
     obtain such a permit.
 
     5.03 Conditions Precedent to Obligation  of the Company. The obligation  of
the  Company to effect the Merger is also subject to the satisfaction or waiver,
at or prior to the Effective Time, of each of the following conditions.
 
          (a) Accuracy of  Representations and  Warranties. All  representations
     and warranties of Parent and Sub contained herein shall be true and correct
     in  all  material respects  as of  the date  hereof  and at  and as  of the
     Closing, with the same  force and effect  as though made on  and as of  the
     Closing  Date unless the failure of  such representations and warranties to
     be true and correct in all  material respects does not, individually or  in
     the  aggregate, materially and adversely affect the value of Parent and its
     subsidiaries taken  as a  whole,  and the  Company  shall have  received  a
     certificate  to  this effect  from the  chief  executive officer  and chief
     financial officer of Parent.
 
          (b) Performance  by Parent  and  Sub. Except  as otherwise  agreed  in
     writing,  each  of Parent  and  Sub shall  have  performed in  all material
     respects all  obligations  and agreements,  and  complied in  all  material
     respects  with all covenants and conditions, contained in this Agreement to
     be performed or complied with  by it on or prior  to the Closing Date,  and
     the Company shall have received a certificate to this effect from the chief
     executive officer and chief financial officer of Parent.
 
          (c) Legal Opinion. The Company shall have received opinions, dated the
     Closing  Date,  of  Willkie  Farr  &  Gallagher  and  S.  Horowitz  &  Co.,
     substantially to  the effect  set forth  in Exhibit  D-1 and  Exhibit  D-2,
     respectively, hereto.
 
          (d)  Accountants'  Letters.  The  Company  shall  have  received  from
     Kesselman & Kesselman the letters referred to in Section 4.09.
 
          (e) Accounting Treatment. The Company  shall have received an  opinion
     in  form and  substance satisfactory  to it  from Ernst  & Young  dated the
     Closing  Date,  stating  that,  in  its  opinion,  there  is  no  fact   or
     circumstance  concerning the Company or  its subsidiaries which would cause
     the Merger  not to  be recorded  for accounting  purposes as  a pooling  of
     interests under US GAAP.
 
          (f)  Affiliate Agreement. Parent shall  have executed and delivered to
     each Person named in Schedule 4.16 an Affiliate Agreement.
 
          (g) Undertakings. Parent shall have delivered undertakings executed by
     each of  its officers  and directors  to refrain  from effecting  sales  of
     Ordinary  Shares  or ADSs  after  the publication  of  financial statements
     reflecting the combined operating results of  the Company and Parent for  a
     period of not less than 30 days from and after the Effective Time.
 
                                      A-29
 
<PAGE>
 
<PAGE>
                                   ARTICLE VI
                          TERMINATION AND ABANDONMENT
 
     6.01  Termination. This  Agreement may  be terminated  and the transactions
contemplated hereby may be abandoned, at  any time prior to the Effective  Time,
whether  before  or after  approval of  the  Merger by  the stockholders  of the
Company:
 
          (a) by mutual consent of the Company,  on the one hand, and of  Parent
     and Sub, on the other hand;
 
          (b)  by either Parent or the Company,  if the Effective Time shall not
     have occurred by August 31, 1996;
 
          (c) by Parent, if the required approval of the Company's  stockholders
     shall  not  have been  obtained  by reason  of  the failure  to  obtain the
     required vote at a duly held meeting of stockholders or at any  adjournment
     thereof;
 
          (d)  by either  Parent or the  Company, if  there shall be  any law or
     regulation of any competent authority that makes consummation of the Merger
     illegal or otherwise prohibited  or if any  judgment, injunction, order  or
     decree  of any competent authority  prohibiting such transaction is entered
     and such judgment, injunction, order or decree shall have become final  and
     nonappealable;
 
          (e)  by either  Parent or  the Company, if  there has  been a material
     breach of any covenant or a breach of any representation or warranty on the
     part of the other, which breach of representation or warranty  individually
     or, together with all other such breaches, materially and adversely affects
     the  value  of the  breaching party,  provided  that any  such breach  of a
     covenant or  representation  or  warranty  has not  been  cured  within  15
     business  days following receipt by the breaching party of notice hereunder
     of such breach;
 
          (f) by the Company in accordance with Section 4.17; provided, however,
     that such termination under  this clause (f) shall  not be effective  until
     the  Company has made payment  of the full fee  required by Section 7.01(c)
     hereof;
 
          (g) by Parent, if the Special Meeting is canceled or is otherwise  not
     held prior to August 15, 1996 except as a result of a judgment, injunction,
     order  or  decree of  any competent  authority  or events  or circumstances
     beyond the reasonable control of the Company; or
 
          (h) by Parent, if (i) the Board of Directors of the Company shall have
     withdrawn or  modified  in a  manner  adverse  to Parent  its  approval  or
     recommendation  to  the Company's  stockholders  of this  Agreement  or the
     Merger or shall have approved or recommended to the Company's  stockholders
     that  they accept the terms of any Takeover Proposal or shall have resolved
     to take any  of the  foregoing actions or  (ii) a  Third Party  Acquisition
     shall  have occurred; provided,  however, that such  termination under this
     clause (h)  shall not  relieve the  Company of  its fee  obligations  under
     Section  7.01(c) hereof. 'Third Party  Acquisition' means the occurrence of
     any of the following events: (x) the acquisition of the Company by  merger,
     tender  offer or  otherwise by  any Person  other than  Parent, Sub  or any
     affiliate thereof (a 'Third Party'); (y)  the acquisition by a Third  Party
     of  20% or more  of the total  assets of the  Company and its subsidiaries,
     taken as a whole; or (z) the acquisition by a Third Party of 20% or more of
     the outstanding Company Common Stock.
 
     6.02 Effect  of  Termination. In  the  event  of the  termination  of  this
Agreement  pursuant to Section 6.01 hereof by Parent or Sub, on the one hand, or
the Company, on the other hand, written notice thereof shall forthwith be  given
to  the other party or parties specifying the provision hereof pursuant to which
such termination  is made,  and this  Agreement shall  become void  and have  no
effect,  and there shall be no liability hereunder on the part of Parent, Sub or
the Company, except that Sections 3.01(o), 3.02(j), 4.03, this Section 6.02  and
Article  VII hereof shall survive any  termination of this Agreement. Nothing in
this Section 6.02  shall relieve any  party to this  Agreement of liability  for
breach of this Agreement or for representations which were incorrect when made.
 
                                      A-30
 
<PAGE>
 
<PAGE>
                                  ARTICLE VII
                                 MISCELLANEOUS
 
     7.01  Fees and Expenses. (a) Except as provided below in this Section 7.01,
all fees and expenses incurred in connection with the Merger, this Agreement and
the transactions contemplated by this Agreement shall be paid by the party  (the
Company,  on the one hand, or Parent and  Sub, on the other hand) incurring such
fees or expenses, whether or not the Merger is consummated.
 
     (b) If this Agreement is terminated by Parent pursuant to Sections 6.01(c),
6.01(e), 6.01(g) or 6.01(h) or by  the Company pursuant to Section 6.01(f),  the
Company shall pay, or cause to be paid, in same day funds to Parent upon demand,
all  actual  out-of-pocket costs  and  expenses of  Parent  and Sub  incurred in
connection  with  this  Agreement  and  the  transactions  contemplated  hereby,
including,   without  limitation,  legal,  professional  and  service  fees  and
expenses. If this  Agreement is terminated  by the Company  pursuant to  Section
6.01(e), Parent shall pay, or cause to be paid, in same day funds to the Company
upon demand, all actual out-of-pocket costs and expenses of the Company incurred
in  connection  with this  Agreement and  the transactions  contemplated hereby,
including,  without  limitation,  legal,  professional  and  service  fees   and
expenses.
 
     (c) The Company shall pay, or cause to be paid, in same day funds to Parent
upon demand a fee of $6,000,000 (the 'Termination Fee') if:
 
          (i)  this Agreement is  terminated by the  Company pursuant to Section
     6.01(f);
 
          (ii) this  Agreement  is  terminated by  Parent  pursuant  to  Section
     6.01(h)(i) or (ii); or
 
          (iii)  this  Agreement is  terminated by  Parent pursuant  to Sections
     6.01(e) and (g) and within 12 months thereafter, the Company enters into an
     agreement with  respect to  a Third  Party Acquisition,  or a  Third  Party
     Acquisition  occurs, involving  any Person  (or any  affiliate or associate
     thereof) (x) with whom the Company (or its agents) had any discussions with
     respect to  a Third  Party Acquisition,  (y) to  whom the  Company (or  its
     agents)  furnished information with  respect to or  with a view  to a Third
     Party Acquisition or (z) who had submitted a Takeover Proposal or expressed
     any interest publicly or  to the Company in  a Third Party Acquisition,  in
     the case of each of clauses (x), (y) and (z) prior to such termination.
 
     (d) Parent shall pay, or cause to be paid, in same day funds to the Company
upon  demand a fee of $6,000,000 if  this Agreement is terminated by the Company
pursuant to  Section 6.01(e)  and within  12 months  thereafter, (i)  Parent  is
acquired  by merger,  tender offer  or otherwise  by any  Person, (ii)  a Person
acquires 20% or more of the total  assets of Parent and its subsidiaries,  taken
as  a  whole, (iii)  a Person  acquires 20%  or more  of the  outstanding Parent
Ordinary Shares,  or (iv)  Parent enters  into an  agreement with  respect to  a
transaction described in (i), (ii) or (iii) hereof.
 
     7.02   Representations,   Warranties   and   Agreements.   The   respective
representations and warranties of the Company,  on the one hand, and Parent  and
Sub,  on  the other  hand,  contained herein  or  in any  certificates  or other
documents delivered prior to  or at the  Closing shall not  be deemed waived  or
otherwise  affected by any investigation made by  any party. Each and every such
representation and warranty  and all  agreements contained  herein shall  expire
with,  and be terminated and extinguished by, the Closing and thereafter none of
the Company, Parent or Sub shall be under any liability whatsoever with  respect
to  any such representation  or warranty or agreement  except those contained in
Sections 2.02, 2.03, 2.05,  3.01(o), 3.02(c), 3.02(j),  4.03, 4.05, 4.14,  4.15,
4.18,  4.20, 4.21 and Article  VII. This Section 7.02  shall have no effect upon
any other obligation of  the parties hereto, whether  to be performed before  or
after the Effective Time.
 
     7.03  Extension;  Waiver. At  any  time prior  to  the Effective  Time, the
parties hereto, by  action taken by  or on  behalf of the  respective Boards  of
Directors  of  the Company,  Parent  or Sub,  may (i)  extend  the time  for the
performance of any of the obligations or other acts of the other parties hereto,
(ii) waive  any inaccuracies  in the  representations and  warranties  contained
herein  by any other applicable party or in any document, certificate or writing
delivered  pursuant  hereto  by  any  other  applicable  party  or  (iii)  waive
compliance  with  any  of the  agreements  or conditions  contained  herein. Any
agreement on
 
                                      A-31
 
<PAGE>
 
<PAGE>
the part of any party to any such extension or waiver shall be valid only if set
forth in an instrument in writing signed on behalf of such party.
 
     7.04 Public Announcements.  The Company, on  the one hand,  and Parent  and
Sub,  on the  other hand,  agree to  consult promptly  with each  other prior to
issuing any press release or otherwise making any public statement with  respect
to  the  transactions contemplated  hereby and  shall not  issue any  such press
release or make any such public statement prior to such consultation and  review
by  the other party of a copy of such release or statement (the comments of such
party to be given reasonable consideration), unless advised by counsel that such
disclosure is required  by applicable  law or the  rules or  regulations of  any
applicable securities exchange.
 
     7.05   Notices.  All   notices,  requests,   demands,  waivers   and  other
communications required or permitted to be  given under this Agreement shall  be
in writing and shall be deemed to have been duly given if delivered in Person or
mailed,  certified or  registered mail with  postage prepaid, or  sent by telex,
telegram or telecopier, as follows:
 
          if to the Company, to it at:
 
           Biocraft Laboratories, Inc.
           18-01 River Road
           Fair Lawn, New Jersey 07410
           Attention: President
           Telecopier #: (201) 797-5270
 
          with a copy to:
 
           Proskauer Rose Goetz & Mendelsohn LLP
           1585 Broadway
           New York, New York 10036
           Attention: Robert A. Cantone, Esq.
           Telecopier #: (212) 969-2900
 
          if to either Parent or Sub, to it at:
 
           Teva Pharmaceutical Industries Limited
           5 Basel Street
           Petach Tikva, 49131, Israel
           Attention: President
           Telecopier #: (972) 3-924-6026
 
          with a copy to:
 
           Willkie Farr & Gallagher
           One Citicorp Center
           153 East 53rd Street
           New York, New York 10022
           Attention: Peter H. Jakes, Esq.
           Telecopier #: (212) 821-8111
 
          and a copy to:
 
           S. Horowitz & Co.
           31 Ahad Haam Street
           Tel Aviv 65543, Israel
           Attention: Asgad Stern, Esq.
           Telecopier #: (972) 3-560-1143
 
or to such  other Person  or address  as any party  shall specify  by notice  in
writing  to  each of  the other  parties. All  such notices,  requests, demands,
waivers and communications shall be deemed to have been received on the date  of
delivery  unless  if mailed,  in which  case  on the  third business  day (fifth
business day, if mailed outside the country of the recipient) after the  mailing
thereof  except for a  notice of a  change of address,  which shall be effective
only upon receipt thereof.
 
                                      A-32
 
<PAGE>
 
<PAGE>
     7.06 Entire Agreement. This Agreement,  the schedules and the exhibits  and
other  documents referred to  herein or delivered  pursuant thereto collectively
contain the  entire understanding  of the  parties hereto  with respect  to  the
subject   matter  contained  herein  and  supersede  all  prior  agreements  and
understandings, oral and written, with respect thereto.
 
     7.07 Binding Effect; Benefit; Assignment. This Agreement shall inure to the
benefit of  and  be  binding  upon  the  parties  hereto  and  their  respective
successors  and permitted  assigns, but  neither this  Agreement nor  any of the
rights, interest  or obligations  hereunder  shall be  assigned  by any  of  the
parties hereto without the prior written consent of the other parties. Except as
otherwise  expressly provided in Section 4.14 hereof, nothing in this Agreement,
expressed or  implied, is  intended to  confer  on any  Persons other  than  the
parties hereto or their respective successors and permitted assigns, any rights,
remedies, obligations or liabilities under or by reason of this Agreement.
 
     7.08  Amendment and Modification. Subject to applicable law, this Agreement
may be  amended, modified  and  supplemented, or  provisions hereof  waived,  in
writing  by the parties hereto in any and all respects before the Effective Time
(notwithstanding any stockholder  approval), by action  taken by the  respective
Boards of Directors of Parent, Sub and the Company or by the respective officers
authorized  by such Boards of Directors,  provided, however, that after any such
stockholder approval, no amendment, modification, supplement or waiver shall  be
made  which by law  requires further approval by  such stockholders without such
further approval.
 
     7.09 Further Actions. Each  of the parties hereto  agrees that, subject  to
its  legal obligations, it will  use its best efforts  to fulfill all conditions
precedent specified herein, to  the extent that such  conditions are within  its
control,   and  to  do  all  things   reasonably  necessary  to  consummate  the
transactions contemplated hereby.
 
     7.10 Headings.  The  descriptive  headings  of  the  several  Articles  and
Sections  of this Agreement are inserted for convenience only, do not constitute
a part  of this  Agreement  and shall  not  affect in  any  way the  meaning  or
interpretation of this Agreement.
 
     7.11  Counterparts. This Agreement may be executed in several counterparts,
each of which shall be deemed to be an original, and all of which together shall
be deemed to be one and the same instrument.
 
     7.12 Applicable Law.  This Agreement  and the legal  relations between  the
parties hereto shall be governed by and construed in accordance with the laws of
the  State of New  York, without regard  to the conflict  of laws rules thereof,
except to the extent the matters provided for herein are required to be governed
by the laws of Israel or the General Corporation Law of the State of Delaware.
 
     7.13  Severability.  If  any  term,  provision,  covenant  or   restriction
contained  in this  Agreement is  held by a  court of  competent jurisdiction or
other authority to  be invalid,  void, unenforceable or  against its  regulatory
policy,  the  remainder of  the  terms, provisions,  covenants  and restrictions
contained in this Agreement shall remain in  full force and effect and shall  in
no way be affected, impaired or invalidated.
 
     7.14  'Person' Defined.  'Person' shall mean  and include  an individual, a
partnership,  a  joint  venture,  a  corporation,  a  trust,  an  unincorporated
organization, a group and a government or other department or agency thereof.
 
     7.15  Submission  to  Jurisdiction. With  respect  to any  suit,  action or
proceeding initiated by a party  to this Agreement arising  out of, under or  in
connection  with this Agreement, the Company,  Parent and Sub each hereby submit
to the non-exclusive jurisdiction of any  state or federal court sitting in  the
State of New York and irrevocably waive, to the fullest extent permitted by law,
any  objection that they may now have or hereafter obtain to the laying of venue
in any such court in  any such suit, action  or proceeding. Parent agrees  that,
within  14 days of the date of this  Agreement, it will appoint and designate CT
Corporation System in the City of New  York, New York located at 1633  Broadway,
New  York, New York, or such other Person as may be satisfactory to the Company,
as its agent  to receive  process in  any such  suit, action  or proceeding  and
agrees  that service  of process on  such agent shall  be deemed to  be in every
respect effective  service  of  process  on  it in  any  such  suit,  action  or
proceeding and waives all claim of error by reason of such service.
 
                                      A-33
 
<PAGE>
 
<PAGE>
     IN  WITNESS WHEREOF, each  of Parent, Sub  and the Company  has caused this
Agreement to be  executed by  their respective officers  or directors  thereunto
duly authorized, all as of the date first above written.
 
                                          TEVA PHARMACEUTICAL INDUSTRIES LIMITED
                                          By:                 /s/ ELI HURVITZ
                                             ...................................
                                            Name: Eli Hurvitz
                                            Title:President and Chief
                                                Executive Officer
 
Attest:
By:             /s/ UZI KARNIEL
     .................................
    Name: Uzi Karniel
    Title:Secretary and
        In-House Counsel
 
                                          GENCO MERGER CORPORATION
                                          By:                 /s/ WILLIAM A.
                                          FLETCHER
                                             ...................................
                                            Name: William A. Fletcher
                                            Title:President
 
Attest:
By:             /s/ PETER H. JAKES
     .................................
    Name: Peter H. Jakes
    Title:Assistant Secretary
 
                                          BIOCRAFT LABORATORIES, INC.
                                          By:                 /s/ HAROLD SNYDER
                                             ...................................
                                            Name: Harold Snyder
                                            Title:Chairman of the Board,
                                                President and Chief
                                                Executive Officer
 
Attest:
By:             /s/ BEATRICE SNYDER
     .................................
    Name: Beatrice Snyder
    Title:Senior Vice President
        and Secretary
 
                                      A-34


<PAGE>
 
<PAGE>
                                                                      SCHEDULE I
 
DESIGNATED DIRECTORS
 
Harold Snyder
Beatrice Snyder
Eli Hurvitz
William Fletcher
Peter Jakes
One Additional Teva Designee
 
<PAGE>
 
<PAGE>
                                                                     SCHEDULE II
 
<TABLE>
<CAPTION>
           DESIGNATED OFFICERS
- ------------------------------------------
 
<S>                                         <C>
William Fletcher..........................  President and Chief Executive Officer
Harold Snyder.............................  Senior Vice President
Peter Terreri.............................  Vice President and Chief Financial Officer, Treasurer
Beatrice Snyder...........................  Vice President -- Cost Accounting and Inventory, Secretary
Beryl L. Snyder...........................  Vice President, General Counsel
Brian S. Snyder...........................  Vice President, Controller
Jay T. Snyder.............................  Vice President -- Research & Product Development
Harmon Aronson............................  Vice President -- Quality Management
Melvin Kaufman............................  Vice President -- Operations
Gerald Moskowitz..........................  Vice President -- Sales
Steven J. Sklar...........................  Vice President -- Finance
Joy Bloodsaw..............................  Associate Vice President -- Purchasing
McKee Moore...............................  Associate Vice President -- Sales
Harvey Richards...........................  Associate Vice President -- Regulatory Affairs
George Svokos.............................  Associate Vice President -- Missouri Operations
</TABLE>
 
<PAGE>
 
<PAGE>
                                                                        ANNEX II
 
                                                                  April 29, 1996
 
Board of Directors
BIOCRAFT LABORATORIES, INC.
18-01 River Road
Fairlawn, NJ 07410
 
Gentlemen and Mesdames:
 
     You  have requested our  opinion as to  the fairness to  the holders of the
outstanding shares of Common Stock, par value $0.01 per share (the 'Shares'), of
Biocraft Laboratories,  Inc. (the  'Company')  of the  exchange ratio  of  0.461
American   Depositary  Shares  ('Teva  American  Depositary  Shares'),  of  Teva
Pharmaceutical Industries Ltd. ('Teva') to be received for each Share, each Teva
American Depositary Share representing ten  Teva ordinary shares, par value  NIS
0.01  each, (the 'Exchange Ratio') pursuant to  the Agreement and Plan of Merger
dated as of  January 29, 1996  by and  among Teva, Genco  Merger Corporation,  a
wholly-owned subsidiary of Teva and the Company (the 'Agreement').
 
     Goldman,  Sachs  & Co.,  as  part of  its  investment banking  business, is
continually engaged  in the  valuation  of businesses  and their  securities  in
connection  with mergers and acquisitions, negotiated underwritings, competitive
biddings, secondary  distributions of  listed and  unlisted securities,  private
placements  and  valuations for  estate, corporate  and  other purposes.  We are
familiar with the Company  having acted as its  financial advisor in  connection
with,  and having  participated in  certain of  the negotiations  leading to the
Agreement.
 
     In connection with this opinion, we have reviewed, among other things,  the
Agreement; Teva's Registration  Statement  on  Form  F-4,  including  the  Proxy
Statement/Prospectus relating to the Special Meeting of stockholders of Biocraft
to  be  held  in  connection  with  the  Merger  Agreement;  Annual  Reports  to
Stockholders  and Annual Reports on Form 10-K of the Company for the five fiscal
years ended March 31, 1995; Annual Reports to Stockholders and Annual Reports on
Form 20-F of Teva for  the six  years ended  December 31, 1995; certain  interim
reports  to  stockholders and  Quarterly Reports  on  Form 10-Q  and 6-K  of the
Company and Teva,  respectively; certain other  communications from the  Company
and  Teva  to  their  respective stockholders;  and  certain  internal financial
analyses and forecasts  for the Company  and Teva prepared  by their  respective
managements. We also have held discussions with members of the senior management
of  Biocraft  and  Teva  regarding the  past  and  current  business operations,
financial condition and future prospects  of their respective companies as  well
as  the future outlook of the combined entity. In addition, we have reviewed the
reported price and trading activity for the Shares and Teva American  Depositary
Shares, compared certain financial and stock market information for Biocraft and
Teva  with similar  information for  certain other  companies the  securities of
which are  publicly  traded, reviewed  the  financial terms  of  certain  recent
business  combinations  and  performed such  other  studies and  analyses  as we
considered appropriate.
 
     We have  relied  without independent  verification  upon the  accuracy  and
completeness  of all of the  financial and other information  reviewed by us for
purposes of  this  opinion.  In  addition,  we  have  not  made  an  independent
evaluation  or appraisal of the assets and liabilities of the Company or Teva or
any of their  respective subsidiaries and  we have not  been furnished with  any
such  evaluation  or appraisal.  We have  assumed, with  your consent,  that the
consummation of the transaction contemplated  pursuant to the Agreement will  be
recorded   as  a  pooling  of  interests  under  generally  accepted  accounting
principles.
 
     Based upon and subject to the  foregoing and based upon such other  matters
as  we consider  relevant, it  is our  opinion that  as of  the date  hereof the
Exchange Ratio pursuant to the Agreement is fair to the holders of Shares.
 
                                          Very truly yours,
 
                                          GOLDMAN, SACHS & CO.


<PAGE>
<PAGE>

                                                          APPENDIX 1


PROXY
                          BIOCRAFT LABORATORIES, INC.
                        SPECIAL MEETING OF STOCKHOLDERS
                                  MAY 31, 1996
          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
 
The  UNDERSIGNED, having received  notice of the  meeting and management's proxy
statement therefor, and  revoking all  prior proxies,  hereby appoint(s)  HAROLD
SNYDER  and BEATRICE  SNYDER, and  each of  them, attorneys  or attorney  of the
undersigned, with  full  power of  substitution,  for and  in  the name  of  the
undersigned,  to represent and to vote the  stock of the undersigned in BIOCRAFT
LABORATORIES, INC. (the 'Company') at  the Special Meeting of Stockholders  held
on  May 31,  1996 and  at any adjournment  thereof as  set forth  below with all
powers the undersigned would possess if personally present:
 
IN THEIR DISCRETION, THE PROXIES ARE AUTHORIZED TO VOTE UPON SUCH OTHER  MATTERS
AS MAY PROPERLY COME BEFORE THE MEETING OR ANY ADJOURNMENT THEREOF.
 
THIS  PROXY WILL  BE VOTED  AS SPECIFIED  AND, UNLESS  OTHERWISE SPECIFIED, THIS
PROXY WILL BE VOTED FOR PROPOSAL 1.
 
Attendance of the undersigned at the meeting or at any adjourned session thereof
will  not  be  deemed  to  revoke  this  proxy  unless  the  undersigned   shall
affirmatively  indicate thereat  the intention of  the undersigned  to vote said
shares in person. If the undersigned hold(s)  any of the shares of Common  Stock
of  the Company in a fiduciary, custodial  or joint capacity or capacities, this
proxy  is  signed  by  the  undersigned  in  every  such  capacity  as  well  as
individually.

<PAGE>
<PAGE>
[X] Please mark your
votes as in this
example

FOR   AGAINST   ABSTAIN
[ ]    [ ]        [ ]

1. PROPOSAL TO APPROVE AND ADOPT THE AGREEMENT AND PLAN OF MERGER dated as of
January 29, 1996 among Teva Pharmaceutical Industries Limited, a company
organized under the laws of the State of Israel ('Teva'), Genco Merger
Corporation,a wholly-owned subsidiary of Teva ('Merger Sub'), and the
Company, providing for the merger of Merger Sub with and into the Company
(the 'Merger'). Pursuant to the Merger, the Company will become a wholly-owned
subsidiary of Teva, and each outstanding share of Common Stock, par value $.01
per share, of the Company will be converted into the right to receive 0.461
American Depositary Shares of Teva ('ADSs'), each ADS representing 10 Ordinary
Shares, par value NIS 0.01 each, of Teva.

2. To transact such other business as may properly come before the
Special Meeting or any adjournment or postponement thereof.

SIGNATURE(S)------------------DATE ------------------------

- ------------------------------DATE ------------------------
Signature if jointly held

NOTE: Please sign exactly as name appears hereon. Joint owners should each
sign. When signing as attorney, executor, administrator, trustee or guardian,
please give full title as such. PLEASE MARK, SIGN, DATE AND RETURN THE PROXY
CARD PROMPTLY USING THE ENCLOSED ENVELOPE.

                                STATEMENT OF DIFFERENCES

The section symbol shall be expressed as .................... SS
The registered trademark symbol shall be expressed as ...... 'r'


<PAGE>



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