RESPONSE ONCOLOGY INC
SC 13D/A, 1996-10-18
SPECIALTY OUTPATIENT FACILITIES, NEC
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<PAGE>

                               UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                 SCHEDULE 13D

                  Under the Securities Exchange Act of 1934
                              (Amendment No. 9)*

                            RESPONSE ONCOLOGY, INC.
                                (Name of Issuer)

                        Common Stock $.01 Par Value (1)
                        (Title of Class of Securities)

                                   761232-107
                                 (CUSIP Number)

                 Lathrop M. Gates, 2345 Grand Blvd., Suite 2800,
                       Kansas City, MO 64108, (816) 292-2000
                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                     10/4/96
             (Date of Event which Requires Filing of this Statement)

If the  reporting  person has  previously  filed a statement  on Schedule 13G to
report the acquisition  which is the subject of this Schedule 13D, and is filing
this  schedule  because of Rule 13d-1(b) (3) or (4),  check the  following  box.

_________

Check the  following box if a fee is being paid with this  statement. _______ (A
fee is not required only if the reporting person:  (1) has a previous  statement
on file reporting beneficial ownership of more than five percent of the class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7).

Note: Six copies of this statement, including all exhibits, should be filed with
the Commission.  See  Rule 13d-1 (a) for  other parties to whom copies are to be
sent.

                         (Continued on following pages)
                             (Page 1 of ___ pages)
                                        
____________________
*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

<PAGE>




(1)     Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

        Seafield Capital Corporation
        43-1039532

(2)     Check the Appropriate Box                      (a) ____  
          if a Member of a Group*                      (b) ____
                                                           

(3)     SEC Use Only

(4)     Source of funds*
        WC

(5)     Check Box if Disclosure of Legal Proceedings is
        Required Pursuant to Items 2(d) or 2(e)            ____

(6)     Citizenship or Place of Organization
        Missouri

        Number of Shares                         (7)  Sole Voting Power
        Beneficially Owned                            6,709,361_1/
        by Each Reporting                          
        Person With                              (8)  Shared Voting Power
                                                      26,067

                                                 (9)  Sole Dispositive Power
                                                      6,709,361_1/

                                                (10)  Shared Dispositive Power
                                                      26,067

(11)    Aggregate Amount Beneficially Owned By Each Reporting Person
        6,735,428_1/

(12)    Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares*
                                                                      __X__
                                                                      

_____________________

        1 Includes  1,678,571  shares which the Report Person could have had the
    right to acquire on the date hereof pursuant to that certain Adjustable Rate
    Convertible  Note  ("Convertible  Note")  described  in  Item 4  hereafter.







                                       2


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(13)    Percent of Class Represented by Amount in Row (11)
        63.7%_2/

(14)    Type of Reporting Person*
        CO

* See Instructions before Filling Out!







































________________________________

        2 Percentage would be 56.9% if shares which the Reporting Person has the
    right to acquire pursuant to the Convertible Note are excluded.




                                       3


<PAGE>


Item 1.      Security and Issuer.

          This Amendment No. 9 ("Amendment No. 9") to  Schedule 13D concerns the
common stock, par value $.01  per  share ("Common  Stock") of Response Oncology,
Inc. (formerly named Response Technologies, Inc.) ("Response"),  whose principal
executive offices are at 1775 Moriah Woods Boulevard, Memphis, Tennessee  38117.
Amendment No. 9  amends an original report (the "Original Report")  on  Schedule
13D respecting a purchase of  shares  of  Common  Stock  on October 31, 1990, as
amended by Amendment No. 1 to Schedule 13D, dated August 2, 1991 ("Amendment No.
1"),  Amendment  No.  2 to Schedule 13D, dated November 11, 1991 ("Amendment No.
2"), Amendment No. 3 to Schedule 13D,  dated  June 9, 1992  ("Amendment No. 3"),
Amendment  No.  4  to  Schedule  13D dated, August 4, 1992  ("Amendment No. 4"),
Amendment  No. 5  to Schedule 13D,  dated  May  13, 1993  ("Amendment  No.  5"),
Amendment No. 6  to Schedule 13D, dated  February 17, 1995  ("Amendment No. 6"),
Amendment No. 7  to  Schedule  13D, dated June 24, 1996 ("Amendment No. 7")  and
Amendment  No.  8  to  Schedule 13D, dated September 4, 1996 ("Amendment No. 8")
(collectively, Amendments No.1, No. 2, No.3, No. 4, No. 5, No.6, No. 7 and No. 8
are  sometimes  referred  to as the "Prior Amendments").  The Issuer is the same
Issuer referred  to  in  the  Original  Report  and in the Prior Amendments; the
current name of the Issuer reflects a change effective November 1995. The Common
Stock is  the same class of stock reported on in  the Original Report and in the
Prior Amendments; the par value of the common stock was changed in November 1995
as a result of a 1 for 5 reverse stock split.

Item 2.    Identity and Background.

           This report is filed by  Seafield  Capital  Corporation  ("Seafield")
(formerly  named BMA  Corporation).  Seafield  is a  Missouri  corporation;  the
address of its principal  executive office is 2600 Grand  Boulevard,  Suite 500,
P.O. Box 410949,  Kansas City,  Missouri  64141.  Seafield is a holding  company
engaged through its subsidiaries in various activities.  Its principal interests
are its 82% owned subsidiary, LabOne, Inc. (formerly named Home Office Reference
Laboratory,  Inc.),  a  provider  of  clinical,  substance  abuse and  insurance
laboratory  testing  services  whose  offices  are  located  at 10310  West 84th
Terrace,   Lenexa,   Kansas  66214,  and  its  interest  in  Response.   Through
subsidiaries,  Seafield also owns oil and gas,  venture  capital and real estate
investments,  as well  as  short-term  and  intermediate-term  investment  grade
securities.

           Set forth in Schedule 1 hereto are the names,  business addresses and
principal  occupations or employment of the executive  officers and directors of
Seafield. Each person listed on Schedule 1 is a United States citizen.

           During the past five years,  neither  Seafield nor to its  knowledge,
any of the persons identified in Schedule 1 has been (i) convicted in a criminal
proceeding,   or  (ii)  a  party  to  a  civil   proceeding  of  a  judicial  or
administrative  body as a result of which  such  person  was or is  subject to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, federal or state securities laws or finding
any violation with respect to such laws.




                                       4


<PAGE>
Item 3.     Source and Amount of Funds or Other Consideration.

           On October 4, 1996 Seafield  entered into a Loan Agreement (the "Loan
Agreement")  with Response;  pursuant to the Loan Agreement  Response may borrow
from Seafield up to $23.5 Million. At Seafield's option,  amounts borrowed under
the Loan  Agreement and evidenced by that certain  Adjustable  Rate  Convertible
Note of  Response,  dated  October  4,  1996  (the  "Convertible  Note")  can be
converted into shares of Response  Common Stock (See Item 4 for a description of
the terms  pursuant  to which such  conversion  can  occur).  On the date hereof
Response's  borrowings  under  the Loan  Agreement  aggregate  $15,520,693.  The
balance  of  the  available  loan  amount  can  be  borrowed  by  Response  from
time-to-time  through  December 31, 1996.  Seafield  anticipates  that all funds
available under the Loan Agreement will be borrowed by Response.  The funds used
to make  advances to  Response  under the Loan  Agreement  were part of, and the
funds used to make future advances will come out of, Seafield's working capital.


Item 4.     Purpose of the Transaction.

         Seafield  entered into the Loan Agreement with Response for the purpose
of providing  financing to enable  Response to further its business  strategy of
acquiring assets of and managing the non-medical aspects of physicians or groups
of  physicians  practicing  in  the  fields  of  oncology  and  hematology.  The
indebtedness provided for in the Loan Agreement and evidenced by the Convertible
Note  matures  August 31,  1998 or earlier  in the event (i)  Response  receives
proceeds  from  either a sale of its equity  securities  or an  issuance  of its
senior  subordinated  indebtedness  and (ii) if such proceeds are received after
December 31, 1996,  Seafield  requests  repayment.  The  Convertible  Note bears
interest until April 1, 1997 at the rate of 8% per annum; thereafter, until July
1, 1997,  at the rate per annum of 10%;  and after June 30, 1997 at the rate per
annum of 12%. Pursuant to a Subordination Agreement dated as of October 4, 1996,
Seafield has subordinated the indebtedness  evidenced by the Convertible Note as
to rights of payment,  security,  collection  and  collection  in  bankruptcy to
obligations  (up to $35  Million in  principal  amount) of  Response  to certain
banks. The indebtedness evidenced by the Convertible Note may be prepaid in full
by  Response  prior to April 1, 1997  without  penalty or  premium;  thereafter,
prepayment requires Seafield's consent.

         The outstanding  principal amount of the indebtedness  evidenced by the
Convertible  Note may be converted in whole or in part and from time to time, at
the option of Seafield,  into shares of Response  Common Stock.  The  conversion
price,  which when divided  into the  principal  of the  Convertible  Note to be
converted  determines the number of shares of Response Common Stock to be issued
as a consequence  of such  conversion,  is, until  December 31, 1996, the market
price of Response Common Stock on the last trading day before the day upon which
a conversion notice is given to Response, and after December 31, 1996 is $11.00.
The maximum number of shares of Response Common Stock which could be acquired by
Seafield if it were to elect to convert the  Convertible  Note  depends upon the
aggregate amount of funds ultimately  advanced to Response  pursuant to the Loan
Agreement and, until January 1, 1997,  depends upon the market price of Response
Common  Stock at the time of  conversion.  At the date hereof,  the  outstanding
principal  amount of the Convertible Note is $15,520,693 and the market price of
Response  Common  Stock  is  approximately  $14 per  share.  If the  outstanding
principal  amount of the Convertible Note were converted on this date (which has
not occurred)  approximately  1,108,620 shares of Response Common Stock would be
acquired by Seafield as a result thereof. If all funds available under the
                                       5


<PAGE>
Loan Agreement had been advanced to Response and the entire  principal amount of
the Convertible  Note were converted prior to January 1, 1997 at a time when the
market  price of Response  Common  Stock is the same as the market  price on the
date hereof, then approximately  1,678,571 shares of Response Common Stock would
be acquired by Seafield as a result of conversion;  this is the number  included
on the cover page as the number of shares which  Seafield has rights to acquire.
If all funds  available  under the Loan  Agreement  are advanced to Response and
conversion of the entire  principal  amount of the Convertible Note occurs after
December 31, 1996,  Seafield would acquire  2,136,363  shares of Response Common
Stock as a result of conversion.

         No  forecast or estimate  of future  market  prices of Response  Common
Stock is intended or made by this  Amendment No. 9, and no assurances  can be or
are being given as to the number of shares of Response  Common Stock which would
be  issued to  Seafield  if it were to  exercise  the  conversion  option in the
Convertible  Note.  Furthermore,  nothing  contained in this  Amendment No. 9 is
intended to suggest  whether or not  Seafield  might  exercise  such  conversion
option;  its exercise is entirely within Seafield's  discretion and Seafield has
not made any decision respecting any such exercise.  Seafield negotiated for the
inclusion  of the  conversion  provisions  in the  Convertible  Note in order to
increase the  flexibility  it has  respecting  the nature of its  investment  in
Response.

         Pursuant  to the Loan  Agreement,  if at  January  1, 1997  either  the
indebtedness evidenced by the Convertible Note remains outstanding or Seafield's
current  ownership  of Response  Common  Stock has not been  reduced by at least
909,000 shares, then, at Seafield's request, Response has agreed to take certain
actions to seek a vote of its shareholders  respecting a  Recapitalization  Plan
(as  defined  in the  Convertible  Note) for  Response,  if one is  proposed  by
Seafield,  and two members of Response's  Board of Directors have agreed to vote
approximately  735,000  shares  of  Response  Common  Stock  in  favor of such a
Recapitalization  Plan, if proposed.  The specific  terms of a  Recapitalization
Plan, other than those set forth in the Loan Agreement,  have not been developed
by Seafield.  Furthermore,  Seafield  has not decided  whether it will propose a
Recapitalization Plan, even if the conditions requiring Response to take certain
actions in connection  therewith  exist, nor has Seafield decided whether or not
it will  request that  Response  take  actions  specified in the Loan  Agreement
relating to a vote of Response's shareholders on a Recapitalization Plan.

         If,  following  a valid  request by  Seafield  for  consideration  of a
Recapitalization  Plan, Response should fail to take required actions respecting
a  shareholder  vote on such a  Recapitalization  Plan or  Response's  Board  of
Directors  does  not  recommend  the  Recapitalization  Plan as  proposed,  then
Response  has agreed to issue a warrant  (the  "Warrant")  to Seafield  granting
Seafield  the right for three  years to  acquire  1,000,000  shares of  Response
Common  Stock at a price per share equal to the lesser of $11 and the average of
the  closing  prices  of  Response  Common  Stock  for  the  five  trading  days
immediately preceding the date on which the Warrant is to be issued.

         Pursuant  to the Loan  Agreement,  Seafield  has  certain  registration
rights  respecting the Convertible  Note, the Warrant and any shares of Response
Common Stock issued upon a conversion of any part of the Convertible  Note or an
exercise of any part of the Warrant.

         The Convertible Note has been, and it is Seafield's present intent that
the  Warrant  and any shares of  Response  Common  Stock  acquired  by  Seafield
pursuant to a conversion of any part of the Convertible  Note or exercise of any
part of the Warrant would be, acquired as an investment.
                                       6
<PAGE>

         It  was  recited  in  Amendment  No.  8,  that  Response  had  filed  a
Registration Statement with the Securities and Exchange Commission in July, 1996
which relates in part to shares of Response Common Stock owned by Seafield,  and
that, in connection with any offering pursuant to said  Registration  Statement,
Seafield  anticipated  granting the underwriters an option to acquire additional
Response shares from Seafield.  However,  no assurances can be or are given that
the Registration  Statement will become effective or that any shares of Response
Common Stock will be sold by Seafield or others pursuant thereto.

         Recently,  Response has  announced  that it is continuing to evaluate a
number of financing options, both private and public. Consistent with Seafield's
previously reported  anticipation that any merger of Seafield with its 82% owned
subsidiary,  LabOne,  Inc.,  would be  preceded  by a  distribution  to Seafield
shareholders, or other disposition by Seafield, of its Response shares, Seafield
intends  to  discuss  with any party  demonstrating  an  interest  in  providing
financing to Response the possible  acquisition  by such party of some or all of
Seafield's Response shares.  However, no assurances can be or are given that any
such acquisition will occur.

           Seafield has stated in the Original  Report and the Prior  Amendments
that, except for rights granted to Seafield in the Securities Purchase Agreement
filed as Exhibit (a) to Amendment No. 6, which rights are no longer material, it
had no plans or proposals which relate to or would result in (i) the acquisition
by any person of  additional  securities  of  Response,  or the  disposition  of
securities of Response;  (ii) an extraordinary  corporate  transaction involving
Response  or any of its  subsidiaries;  (iii) a sale or  transfer  of a material
amount of assets of Response or any of its subsidiaries;  (iv) any change in the
present board of directors or management of Response; (v) any material change in
the  present  capitalization  or  dividend  policy of  Response;  (vi) any other
material change in Response's business or corporate structure;  (vii) any change
in Response's  charter or bylaws which may impede the  acquisition of control of
Response by any person;  (viii)  causing a class of Response's  securities to be
delisted from a national  securities exchange or to cease to be authorized to be
quoted in an inter-dealer  quotation system of a registered  national securities
association;  (ix) a class of equity  securities of Response  being eligible for
termination  of  registration  pursuant to Section  12(g)(4)  of the  Securities
Exchange Act of 1934; or (x) any act similar to any of those  enumerated  above.
The foregoing statement remains accurate, except as otherwise set forth herein.

         Item 5.     Interest in Securities of the Issuer.

           (a), (b), (c) and (d)

           At present,  Seafield  beneficially owns 6,735,428 shares of Response
Common Stock; of which Seafield  currently has sole power to vote and dispose of
6,709,361 shares;  however, both of those numbers include 1,678,571 shares which
Seafield could have the right to acquire  pursuant to the  conversion  option in
the convertible  Note if all of the funds available under the Loan Agreement are
advanced to Response and the conversion price were equal to the market price for
Response Common Stock on the date hereof (i.e.,  $14.00). With respect to 26,067
shares  which have been  pledged to  Seafield  ("Pledged  Shares")  to secure an
indebtedness of a member of Response's management to Seafield, Seafield does not
have the right to exercise  any voting or other rights  (including  the right to
dividends)  unless  a  default  under  the  note  evidencing  such  indebtedness
("Secured Note") or the pledge agreement  respecting such indebtedness  ("Pledge
Agreement")  occurs.  All such rights,  including the right to dividends on such
shares are retained by the owner of
                                       6
<PAGE>

such shares,  who was the beneficiary of such  indebtedness,  unless and until a
default  occurs.  Defaults  include (i) failure to pay any obligation  under the
Secured  Note or Pledge  Agreement  when the same is due,  (ii) the death of the
beneficiary  of such  indebtedness,  the failure of the  beneficiary  to pay his
debts  or  the   institution  of  bankruptcy   proceedings  by  or  against  the
beneficiary,  or (iii) the breach of any  representation,  warranty or agreement
made by the beneficiary in the Secured Note or the Pledge  Agreement.  If such a
default occurs, Seafield has rights under the Pledge Agreement which include the
right to (a)  receive all cash  dividends  payable  with  respect to the Pledged
Shares,  (b)  exercise  any and all voting and other  rights with respect to the
Pledged  Shares,  and (c) cause the Pledged  Shares to be  transferred of record
into Seafield's name or the name of Seafield's nominee.

           The  number  of shares  beneficially  owned by  Seafield  constitutes
approximately  63.7% of  Response's  outstanding  Common  Stock,  calculated  in
accordance with Exchange Act Rule 13d-3(d)(1).  The percentage would be 56.9% if
the number of shares  which  Seafield  has the right to acquire  pursuant to the
conversion option in the Convertible Note is excluded.  These percentages do not
reflect shares subject to issue upon exercise of warrants, stock options or upon
conversion  of  shares  of  Series A  Convertible  Preferred  Stock of  Response
presently outstanding and owned by persons other than Seafield.

           Certain of the  persons  named in Schedule 1 are known by Seafield to
beneficially own shares of Response stock. To Seafield's knowledge, these shares
were acquired by such persons  solely for  investment  purposes  and,  except as
noted below with respect to Mr. Herman, such persons have sole power to vote and
dispose of such shares.  Seafield  disclaims any beneficial  ownership in any of
such shares.  The persons known to Seafield to beneficially  own such shares and
the number of such shares beneficially owned by such persons (with an indication
of the shares which there is a right to acquire) are as follows:

                  Name                            Number of Shares

            Joseph T. Clark                           226,640
            W. Thoms Grant, II                          8,400
            Michael E. Herman                             360
            P. Anthony Jacobs                          12,400
            James R. Seward                            12,400

Of the number of shares shown above,  the following  numbers  consist of options
which the indicated  individuals  have the right to exercise either presently or
within 60 days: for Joseph T. Clark, 221,840; for W. Thomas Grant II, 8,000; for
P. Anthony Jacobs, 8,000 and for James R. Seward, 8,000. Of the number of shares
shown above as beneficially  owned by Mr. Herman, all are owned by his wife, and
he disclaims beneficial ownership.

           (e)     Not Applicable.

Item 6.     Contracts, Arrangements, Understanding or Relationships with Respect
to Securities of the Issuer.

           In the event a  Recapitalization  Plan is proposed  by  Seafield  and
submitted for approval by Response  shareholders (see Item 4 for a discussion of
the circumstances  under which a Recapitalization  Plan might be so proposed and
submitted), two of the members of Response's Board

                                       8

<PAGE>



of Directors have agreed,  pursuant to Voting  Agreements dated October 4, 1996,
to vote an aggregate of approximately 735,000 shares of Response Common Stock in
favor of such a Recapitalization Plan.

Item 7.     Exhibits.

         99.1     Loan  Agreement  between  Seafield  and  Response, dated as of
                  October 4, 1996.

         99.2     Adjustable Rate Convertible Note of Response, dated October 4,
                  1996.

         99.3     Subordination   Agreement,   among   Response,   Seafield  and
                  NationsBank of Tennessee,  N.A., as Agent, dated as of October
                  4, 1996.

         99.4     Form of Voting  Agreement,  dated October 4, 1996; one between
                  Seafield and William H. West,  M.D.  relates to  approximately
                  635,000  shares  of  Response  Common  Stock  and one  between
                  Seafield  and  Frank  M.  Bumstead  relates  to  approximately
                  100,000 shares of Response Common Stock.

         99.5     Form of  Warrant,  relating  to rights  which  Seafield  could
                  acquire to  purchase  shares of Response  Common  Stock if the
                  circumstances  referred  to in  Item 4  occur  so as to  cause
                  Response to issue the Warrant.



























                                       9


<PAGE>




         SIGNATURE

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.


         SEAFIELD CAPITAL CORPORATION


         By:  /s/ P. Anthony Jacobs
             ----------------------------
             P. Anthony Jacobs, President


         Date:    October 16, 1996




































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<PAGE>



SCHEDULE 1


          Directors of Seafield Capital Corporation

          Name, Occupation and Business Address

Lan C. Bentsen, Managing Partner
Remington Partners (investments)
3040 Post Oak Boulevard, Suite 200
Houston, Texas  77056

John C. Gamble, Managing Partner
Allen, Matkins Leck, Gamble and Mallory (law)
18400 Von Karmen, 4th Floor
Irvine, California  92715

William D. Grant, Consultant
Seafield Capital Corporation
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

W. Thomas Grant, II, Chairman  of the Board and Chief Executive Officer/Seafield
Capital  Corporation;  Chairman  of  the  Board,  President  and Chief Executive
Officer/LabOne, Inc.
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

Michael E. Herman
Private Investor
9300 Ward Parkway
Post Office Box 8480
Kansas City, Missouri  64114

P. Anthony Jacobs, President and Chief Operating Officer
Seafield Capital Corporation, 2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

David W. Kemper, Chairman, President and Chief Executive Officer
Commerce Bancshares, Inc. (banking)
1000 Walnut Street, 18th Floor
Kansas City, Missouri  64106








                                      11


<PAGE>




John H. Robinson, Jr., Managing Partner
Black & Veatch (design and construction)
Corporate Woods, Building 27
10975 Grandview
Overland Park, Kansas  66210

James R. Seward, Executive Vice President and Chief Financial Officer
Seafield Capital Corporation
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

Dennis R. Stephen, Chief Operating Officer
Tennessee Farmers Insurance Companies (insurance)
Post Office Box 307
Columbia, Tennessee  38401

          Executive Officers of Seafield Capital Corporation

           Name,  Position and Business Address

W. T. Grant, II
Chairman of the Board and Chief Executive  Officer/Seafield  Capital Corporation
Chairman of the Board, President and Chief Executive Officer/LabOne, Inc.
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

P. Anthony Jacobs, President and Chief Operating Officer
Seafield Capital Corporation
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

James R. Seward, Executive Vice President and Chief Financial Officer
Seafield Capital Corporation
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141

Steve K. Fitzwater, Vice President, Chief Accounting Officer and Secretary
Seafield Capital Corporation
2600 Grand Boulevard, Suite 500
Post Office Box 410949
Kansas City, Missouri  64141







                                      12


<PAGE>



Joseph T. Clark, President and Chief Executive Officer
Response Oncology, Inc.
1775 Moriah Woods Boulevard
Memphis, Tennessee  38117

















































                                      13


<PAGE>


                                EXHIBIT INDEX


Ex.      99.1     Loan  Agreement  between  Seafield  and  Response, dated as of
                  October 4, 1996.

Ex.      99.2     Adjustable Rate Convertible Note of Response, dated October 4,
                  1996.

Ex.      99.3     Subordination Agreement, among Response, Seafield and 
                  NationsBank of Tennessee, N.A., as Agent, dated as of 
                  October 4, 1996.

Ex.      99.4     Form  of Voting Agreement, dated  October 4, 1996; one between
                  Seafield  and  William H. West, M.D.  relates to approximately
                  635,000  shares  of  Response  Common  Stock  and  one between
                  Seafield  and  Frank  M.  Bumstead  relates  to  approximately
                  100,000 shares of Response Common Stock.

Ex.      99.5     Form  of  Warrant,  relating  to  rights  which Seafield could
                  acquire  to  purchase  shares  of Response Common Stock if the
                  circumstances  referred  to  in  Item  4  occur so as to cause
                  Response to issue the Warrant.































                                      14


<PAGE>






















































<PAGE>

                                                                    EXHIBIT 99.1



                                 LOAN AGREEMENT



         This Loan Agreement is made as of the 4th day of October, 1996, between
Response  Oncology,  Inc.,  a Tennessee  corporation  ("Company")  and  Seafield
Capital Corporation, a Missouri corporation ("Lender").

         WHEREAS,   the  Company  has   requested  the  Lender  to  loan  up  to
Twenty-Three Million Five Hundred Thousand Dollars ($23,500,000) to the Company,
in one or more  installments,  primarily  to provide  acquisition  financing  in
connection with the Company's acquisitions of the New Oncology Practices; and

         WHEREAS, the Lender is willing to make the loan to the Company upon the
terms and  conditions set forth herein and in the  Adjustable  Rate  Convertible
Note ("Note"), a copy of which is attached hereto as Exhibit A.

         NOW, THEREFORE,  in consideration of the premises,  the mutual promises
herein  contained  and for other good and  valuable  consideration  the  receipt
whereof is hereby acknowledged, the parties agree as follows:

         1.   Definitions.  Capitalized terms used in this Loan Agreement which
are not defined herein shall have the meanings ascribed to them in the Note.

         2. Loan;  Advances.  Subject to the terms and  conditions  of this Loan
Agreement  and the Note and  provided  there  does not exist an Event of Default
hereunder or under the Note or any event or condition  which with notice,  lapse
of time or the  advance  of funds  would  constitute  such an Event of  Default,
Lender  agrees  to  loan  up to  $23,500,000  to the  Company,  in  one or  more
installments, as requested by the Company, subject to the following:

              (a) Each  request for an advance of funds  hereunder  must include
       the  Company's  representation  as to the  use to be  made  of the  funds
       requested.

              (b) No more than  $3,000,000  of funds  advanced  hereunder can be
       used for Company working capital.

              (c) Except for funds to be used for working capital,  as specified
       above, all funds advanced  hereunder must be used to pay a portion of the
       acquisition price for one or more of the New Oncology Practices and funds
       to be used for such purposes must be applied to such purposes  within one
       business day after an advance.

              (d) No advance of funds will be made hereunder  after December 31,
       1996.






                                                    

<PAGE>



              (e) No  advance  of funds  will be made  hereunder  if at the time
       there exists an Event of Default  hereunder or under the Note or an event
       or  condition  which with  notice,  lapse of time or the advance of funds
       would constitute such an Event of Default.

              (f) No advance of funds will be made after the  Company  has given
       written notice to Lender of a redemption of all or a part of the Note.

              (g) The aggregate of all funds advanced hereunder shall not exceed
       $23,500,000.

All loans and  advances by the Lender to the Company  under this Loan  Agreement
and the Note,  constitute one loan and all  indebtedness  and obligations of the
Company  under this Loan  Agreement  and the Note shall  constitute  one general
obligation  of the Company  which will be  evidenced by the Note and governed by
the terms and conditions of the Note and this Loan Agreement.

         3.  Subordination.  The loan  evidenced  by the Note will be subject to
that  certain  Subordination  Agreement  dated as of October 4, 1996,  among the
Company, the Lender and NationsBank of Tennessee,  N.A., as Agent.  Reference is
made to said  Subordination  Agreement for the terms and provisions  pursuant to
which the  indebtedness  evidenced by the Note is subordinated to obligations of
the Company to the Lenders under that certain Loan Agreement dated as of May 31,
1996, among the Company and the banking institutions which are a party thereto.

         4.  Shareholder  Approval of Conversion  Price and Warrant.  As soon as
practicable,  and in any  event  within  15 days  after  the  date of this  Loan
Agreement,  the Company shall call a special  meeting of its  shareholders,  and
within 30 days after such a special  meeting has been  called the Company  shall
hold  such  special  meeting,  for the  purpose  of  obtaining  the  Shareholder
Approval.

         5.   Recapitalization Plan.

              (a) Unless all  principal  of and  interest on the Note is paid in
       full prior to January 1, 1997 and simultaneously therewith 909,000 shares
       of the Company's  Common Stock are  purchased  from the Lender at a price
       per share of $11.00, the Company shall, within 30 days after the later of
       (i) the  earlier  of (x)  January 1, 1997 and (y) the date upon which the
       principal of and interest on the Note is paid in full,  and (ii) the date
       upon which the Lender submits to the Company in writing a request for and
       the terms of a  Recapitalization  Plan (such later date being the "Notice
       Date"),  file a  preliminary  proxy  statement  with the  Securities  and
       Exchange  Commission  providing for, among other things, a meeting of the
       Company's  shareholders,  to be held not  later  than 120 days  after the
       Notice Date, for the







                                       2


<PAGE>



       purpose of obtaining all Required Approvals by said shareholders of the
       Recapitalization Plan.

              (b) The Company  agrees to use its best  efforts to hold a meeting
       of its  shareholders on or before the 120th day following the Notice Date
       for the purpose of obtaining all Required  Approvals by said shareholders
       of the Recapitalization Plan.

              (c) When the Company becomes obligated  pursuant to this Section 5
       to call a meeting of the Company's  shareholders,  the Company shall,  to
       the extent reasonably  requested by Seafield forthwith and thereafter use
       its best  efforts  to:  (i) cause  the  recapitalization  of the  Company
       pursuant  to the  Recapitalization  Plan to be  tax-free  for federal and
       state income tax purposes,  including without limitation cooperating with
       Seafield  to  develop  and  set  forth  in  the  Recapitalization  Plan a
       statement of the Company's purposes for carrying out the recapitalization
       contemplated  therein;  (ii) permit the  Capital  Stock of the Company to
       continue to be listed by the National  Association of Securities Dealers,
       Inc.  on its  National  Market  Quotation  System;  and  (iii)  cause any
       distribution by Seafield to its  shareholders of the Capital Stock of the
       Company owned by Seafield  immediately after the  recapitalization  to be
       tax-free  under  Section  355  of  the  Code;  provided,   the  Company's
       obligations  pursuant  to this  Section  5(c) shall cease if and when the
       Recapitalization  Plan  is  disapproved  by a vote of a  majority  of the
       Company's shareholders other than Lender; and provided further, that such
       acts of the Company do not cause any  violation by the board of directors
       of its fiduciary  responsibilities  to all shareholders of the Company or
       cause a material  departure  from the  business  plans of the  Company as
       established  by its board of  directors or  materially  impair its future
       prospects. A request made by Seafield shall be deemed to be reasonable if
       it is, in the opinion of  Seafield's  counsel,  necessary or  appropriate
       either  to  satisfy  the  substantive  requirements  of the  Code and the
       regulations  thereunder or other law or to obtain advance  administrative
       approval of transactions by the Internal  Revenue  Service,  the National
       Association  of  Securities  Dealers,   Inc.,  or  other   administrative
       authority,  so long as such request is not  inconsistent  with the second
       proviso above.

              (d) In the event of a Warrant  Issuance  Event,  the Company shall
       immediately  issue to the  Lender a  Warrant  in the  form of  Exhibit  B
       attached hereto pursuant to which Lender would have the right to purchase
       1,000,000  shares  of the  Company's  Common  Stock for a price per share
       equal to the  lesser  of (i) the  average  of the  closing  prices of the
       Common Stock on the NASDAQ Stock  Market's  National  Market for the five
       (5) consecutive trading days ending one (1) trading day prior to the date
       on which the Warrant  Issuance  Event  occurs (for  purposes of computing
       such average, such closing trading prices shall be appropriately adjusted
       to eliminate the impact of any dividend,  whether in cash,  securities or
       other property, stock split, reclassification,  recapitalization, reverse
       split or similar event, announced or



                                       3


<PAGE>



       occurring with respect to the Company's Common Stock during such five (5)
       trading day period) and (ii) $11.00. The Warrant shall be exercisable for
       three years from the Warrant  Issuance Event and shall  otherwise be upon
       such  terms  and  conditions  as are set  forth  in the  form of  warrant
       attached as Exhibit B hereto.  Notwithstanding anything contained in this
       subsection (c) to the contrary,  the number of warrants which the Company
       shall be  obligated  to issue to the  Lender  shall not exceed the number
       specified  above,  notwithstanding  that more than one  Warrant  Issuance
       Event may  occur;  said  Warrant  shall be issued by the  Company  to the
       Lender upon the occurrence of the first Warrant Issuance Event to occur.

         6.  Representations, Warranties and Covenants.  The Company represents,
warrants and covenants to the Lender as follows:

              (a)  The  Company  is a  corporation  duly  incorporated,  validly
       existing and in good  standing  under the laws of the State of Tennessee,
       and is duly  qualified to transact  business  and is in good  standing in
       each  jurisdiction  where  the  nature  and  extent of its  business  and
       property require the same.

              (b) The Company has all  requisite  power and  authority  to enter
       into this Loan Agreement,  the Note and any other documents  executed and
       delivered by it in connection with the  transaction  contemplated by this
       Loan Agreement and the Note. No authorization, consent, approval, license
       or  exemption  of,  and  no  registration,   qualification,  designation,
       declaration  or  filing  with,  any  court  or  governmental  department,
       commission,  board,  bureau,  agency  or  instrumentality,  and no  vote,
       authorization,  consent or approval of  shareholders of the Company is or
       was necessary to the valid  execution,  delivery and  performance of this
       Loan Agreement and the Note, the making of the borrowing  contemplated by
       the  provisions   hereof  and  thereof,   the  execution,   delivery  and
       performance of all other  agreements and instruments  contemplated by the
       provisions of this Loan  Agreement or the Note to be executed,  delivered
       and performed by the Company,  or the  consummation  of the  transactions
       herein or therein contemplated, except for the shareholder votes required
       in connection with the  Recapitalization  Plan and in order to obtain the
       Shareholder Approval. Each of this Loan Agreement, the Note and the other
       documents  and  instruments  executed  and  delivered  by the  Company in
       connection  with the  transactions  contemplated  hereby  have  been duly
       authorized  on behalf of the Company and when  executed and  delivered by
       the Company, each will constitute the legal, valid and binding obligation
       of the Company, enforceable in accordance with their respective terms.

              (c)  Except  as  described  in  the  Officer's  Certificate,   the
       execution,  delivery and performance of this Loan Agreement, the Note and
       any other documents or instruments  executed and delivered by the Company
       in connection with the  transactions  contemplated by this Loan Agreement
       and the performance by the





                                       4


<PAGE>



       Company of its obligations  under this Loan Agreement,  the Note and such
       other  documents  and  instruments  do not conflict with any provision of
       law, rule or regulation,  or the articles of  incorporation or the bylaws
       of the Company or of any material  agreement  binding upon the Company or
       to which any property of the Company may be subject.

              (d) If the conversion privilege afforded to the Lender in the Note
       is  exercised,  all  shares  of Common  Stock to be issued to the  Lender
       pursuant thereto will, when issued,  constitute duly authorized,  validly
       issued and outstanding,  fully paid and  non-assessable  shares of Common
       Stock of the  Company.  Furthermore,  in the event of a Warrant  Issuance
       Event, the Warrant will, when issued to the Lender, constitute the legal,
       valid and binding obligation of the Company to issue the number of shares
       of Common Stock  specified  therein  upon  exercise of the Warrant by the
       Lender  in  accordance  with the  provisions  thereof.  In the  event the
       Warrant is  exercised  in whole or in part,  the  shares of Common  Stock
       issued pursuant thereto will, when issued,  be duly  authorized,  validly
       issued and outstanding,  fully paid and  non-assessable  shares of Common
       Stock of the Company.

              (e) The Company covenants that during the respective  periods that
       the  conversion  rights  contained in the Note exist and during which the
       Warrant may be  exercised,  the Company will reserve from its  authorized
       and  unissued  shares of Common  Stock a  sufficient  number of shares to
       provide for the issuance of Common Stock upon the  conversion of the Note
       and the exercise of the Warrant,  as the case may be. The Company  agrees
       that its  issuance  of the Note and the  Warrant  shall  constitute  full
       authority  to its  officers  and agents who are charged  with the duty of
       executing   stock   certificates  to  execute  and  issue  the  necessary
       certificates  for shares of Common Stock upon the  conversion of the Note
       or any part thereof, or the exercise of the Warrant or any part thereof.

              (f) The Company covenants and agrees that upon any exercise of the
       conversion right afforded the Lender in the Note, the Company shall cause
       an opinion of counsel acceptable to the Lender to be issued to the Lender
       to the effect that the shares of Common Stock issued in  connection  with
       said   conversion   constitute  duly   authorized,   validly  issued  and
       outstanding,  fully and  non-assessable  shares of the  Company's  Common
       Stock. Further, upon the exercise of the Warrant or any part thereof, the
       Company  covenants  and  agrees  that it will cause an opinion of counsel
       acceptable  to the Lender to be issued to the  Lender to the effect  that
       the  shares  of Common  Stock  issued in  connection  with such  exercise
       constitute duly authorized,  validly issued and  outstanding,  fully paid
       and non-assessable shares of Common Stock of the Company.

         7.   Conditions to the Lender's Obligations.  The obligation of the 
Lender to make any advances hereunder or under the Note is subject to the 
accuracy of and





                                       5


<PAGE>



compliance with, as of the date hereof, the  representations  and warranties and
covenants  herein  contained and to the  satisfaction  of the following  further
conditions:

             (a) The  Company  and all other  appropriate  parties  shall  duly
       execute  and  deliver  to  Lender  the Loan  Agreement,  the Note and the
       Subordination Agreement.

             (b)  William H. West, M.D. and Frank M. Bumstead shall duly execute
       and deliver to the Lender a Voting Agreement in the form of Exhibit C 
       hereto.

             (c) The  Company  shall  deliver  to Lender an  opinion of counsel
       acceptable  to the Lender  dated the date of the Loan  Agreement,  to the
       following effect:

                      (i) The Company is a corporation  duly organized,  validly
              existing  and in good  standing  under  the  laws of the  State of
              Tennessee.

                     (ii) The Company has the  corporate  power and authority to
              enter into,  execute and deliver the Loan  Agreement  and the Note
              and to perform its  obligations  under the Loan  Agreement and the
              Note.

                    (iii) The  execution and delivery by the Company of the Loan
              Agreement and the Note and the  performance  by the Company of its
              obligations  thereunder have been duly authorized by all requisite
              corporate action,  and will not conflict with any federal or state
              law,  rule or  regulation,  and  any  rule  or  regulation  of any
              regulatory or self-regulatory agency or body, any provision of the
              charter or bylaws of the Company or any term or  provision  of any
              material agreement of the Company known to said counsel.

                     (iv) The Loan  Agreement and the Note are the legal,  valid
              and binding  obligations of the Company,  enforceable  against the
              Company in  accordance  with their  respective  terms,  subject to
              customary exceptions for insolvency laws and equitable principles.

         8.   Events of Default.  Each of the following shall constitute an 
Event of Default under this Loan Agreement:

              (a)  The occurrence or existence of Event of Default under the 
       Note.

              (b)  A breach of any representation or warranty of the Company 
       contained in this Loan Agreement.

              (c) A default in the  performance,  or breach,  of any covenant or
       agreement of the Company under this Loan  Agreement,  and  continuance of
       such  default or breach for a period of thirty  (30) days after there has
       been given to the Company by the

                                       6


<PAGE>



       Lender a written  notice  specifying  such  default or breach and stating
       that such notice is a "Notice of Default."

         9.  Remedies.  In the case of one or more Events of Default  under this
Loan Agreement,  subject to the Subordination  Agreement,  the Lender shall have
all  remedies  provided  to it under the Note and in  addition  may  proceed  to
protect and  enforce  its rights by suit and equity,  or by action at law, or by
other  appropriate  proceeding,  whether  for the  specific  performance  of any
covenant or agreement  contained in this Loan Agreement or in the Note or in any
of the other  agreements  or  instruments  executed by the Company in connection
herewith, or in aid of the exercise of any power granted in this Loan Agreement,
in the Note or in such other documents or instruments  upon the occurrence of an
Event of Default as defined herein, or may proceed to enforce the payment of the
Note or to enforce any other legal or equitable  right of the holder of the Note
or under this Loan Agreement. In particular,  without limiting the generality of
the foregoing,  but subject to the  Subordination  Agreement,  the Lender or any
other  subsequent  holder of the Note shall have the right to declare the entire
unpaid principal of and all interest  accrued on, the indebtedness  evidenced by
the Note then  outstanding to be and such  indebtedness  and the Note evidencing
said indebtedness shall thereupon become, forthwith due and payable, without any
presentment,  demand,  protest  or other  notice of any  kind,  all of which are
hereby expressly waived, and the Company will forthwith pay to the holder of the
Note the entire  outstanding  principal of and  interest on the Note,  and other
charges or  obligations  provided for in this Loan  Agreement or in the Note. In
case any one or more Events of Default  shall have  occurred and be  continuing,
the Lender or any subsequent  holder of the Note may, at its option,  rectify or
cure such Event of Default for the account and at the expense of the Company and
all sums so advanced for such purpose,  together  with  interest  thereon at the
Note  Rate,  from the date of  expenditure  to the date of  repayment,  shall be
deemed  part of the  indebtedness  evidenced  by the Note  and,  subject  to the
Subordination  Agreement,  shall be due and payable  upon  demand.  No course of
dealing  on the part of the  holder of the Note or any delay or  failure  on the
part of such  holder to  exercise  any right  shall  operate as a waiver of such
right or otherwise prejudice such holder's rights,  powers and remedies.  If the
Company fails to pay when due the principal of or interest on the Note, or other
charges or  obligations  provided for in this Loan  Agreement or in the Note, or
fails to comply with any other provision of this Loan Agreement or the Note, the
Company will pay to the holder of the Note, to the extent permitted by law, such
further  amounts  as shall  be  sufficient  to cover  the  costs  and  expenses,
including but not limited to reasonable attorneys' fees, incurred by such holder
in collecting any sums due on or on account of the indebtedness evidenced by the
Note or this Loan Agreement or otherwise in enforcing any of its rights.











                                       7


<PAGE>




         10.       Registration Rights.

              (a) The Note.  Subject  to the terms and  provisions  set forth in
       Section  5.1  of  that  certain  Securities  Purchase  Agreement,   dated
       September  26, 1990,  between the Company and the Lender,  as amended (as
       amended,  the  "Securities  Purchase  Agreement"),  in the event that the
       Lender  shall so request by written  notice to the  Company,  the Company
       shall,  at the  Company's  cost  and  expense  (except  for  underwriting
       discounts  and  commissions),  as soon as practical  after the receipt of
       such written  notice,  file with the Securities  and Exchange  Commission
       (the  "Commission") a Registration  Statement under the Securities Act of
       1933,  as  amended  (as then in effect  or any  similar  statute  then in
       effect) or under the Securities Exchange Act of 1934, as amended (as then
       in effect or any similar  statute  then in effect),  as  requested by the
       Lender, covering in a single Registration Statement the offering and sale
       or  other  assignment  of  the  Note  requested  to be  covered  by  such
       Registration  Statement,  and the  Company  will use its best  efforts to
       cause such Registration Statement to become effective as expeditiously as
       possible.

              (b)  Common  Stock.   The  Company  shall  have  the  same  demand
       registration rights and piggyback registration rights with respect to all
       shares of the Company's Common Stock issued upon a conversion of the Note
       or any part  thereof  or upon the  exercise  of the  Warrant  or any part
       thereof  as  are  afforded  to the  Lender  in  the  Securities  Purchase
       Agreement.

              (c)  Warrant.  Subject  to the terms and  conditions  set forth in
       Section 5.1 of the Securities Purchase  Agreement,  in the event that the
       Lender  shall so request by written  notice to the  Company,  the Company
       shall,  at the  Company's  costs and  expense  (except  for  underwriting
       discounts  and  commissions),  as soon as practical  after the receipt of
       such written  notice,  file with the Commission a Registration  Statement
       under the  Securities  Act of 1933,  as amended (as then in effect or any
       similar  statute then in effect) or the Securities  Exchange Act of 1934,
       as  amended  (as then in effect or any  similar  statute  then in effect)
       covering  the  offering  and sale or other  distribution  of the  Warrant
       requested to be covered by such Registration  Statement,  and the Company
       will use its best efforts to cause such Registration  Statement to become
       effective as expeditiously as possible.

         11.       General.

              (a)  Notices.  Any communications concerning this Loan Agreement 
       or the Note shall be addressed as follows:







                                       8


<PAGE>




         As to Lender:

                  Seafield Capital Corporation
                  Attention:  P. Anthony Jacobs
                  2600 Grand Boulevard, Suite 500
                  Kansas City, MO 64108
                  Telecopier: (816) 842-2101

         With a Copy to:

                  Lathrop M. Gates
                  Lathrop & Gage L.C.
                  2345 Grand Boulevard
                  Kansas City, MO 64108
                  Telecopier: (816) 292-2001

         As to Company:

                  Response Oncology, Inc.
                  Attention: Joseph P. Clark
                  1775 Moriah Woods Blvd.
                  Memphis, Tennessee 38117
                  Telecopier: (901) 683-7277

         With a copy to:

                  Waring Cox PLC
                  Attention: Sam D. Chafetz
                  50 N. Front Street, Suite 1300
                  Memphis, TN 38103
                  Telecopier: 901-543-8036

              (b)  Severability.  Any provision of this Loan Agreement or of the
       Note which is prohibited or unenforceable  in any jurisdiction  shall, as
       to such jurisdiction, be ineffective to the extent of such prohibition or
       enforceability  without  invalidating the remaining  provisions hereof or
       thereof or affecting the validity or  enforceability of such provision in
       any other  jurisdiction,  it being the intent of the parties  hereto that
       the remaining  provisions  hereof or thereof shall be construed in such a
       manner as to give maximum meaning and effect thereto as if the invalid or
       unenforceable  provision  were never a part of this Loan Agreement or the
       Note.










                                       9


<PAGE>



              (c) Law.  This Loan  Agreement  shall be a  contract  made  under,
       governed by and construed in  accordance  with the internal laws (without
       giving effect to the conflict of laws rules) of the State of Missouri.

              (d)  Successors.  This Loan  Agreement  shall be binding  upon the
       parties  hereto and their  respective  successors  and  assigns and shall
       inure to the benefit of such parties and their respective  successors and
       assigns; provided,  however, that Company shall not assign this Agreement
       or any of its rights or duties  hereunder or under the Note,  without the
       prior written consent of the Lender.

              (e)  Section Headings.  The section headings and captions in this
       Loan Agreement are for convenience only and shall not affect the 
       construction hereof.

              (f) Counterparts.  This Loan Agreement may be executed in multiple
       counterparts   and  by  the  parties   hereto  on   separate,   identical
       counterparts;  each shall be  considered  an  original,  but all of which
       shall constitute one single agreement.

              (g) Entire Agreement.  All negotiations between the parties hereto
       are  merged in this  Loan  Agreement  and in the  Note,  and there are no
       understandings or agreements other than those  incorporated  herein or in
       the Note.

              (h)  Assignment  and Transfer.  The Lender shall have the right to
       assign and transfer any or all of its rights and  privileges  pursuant to
       this Loan Agreement or the Note,  which  assignment may be in whole or in
       part  (including  without  limitation an assignment of certain rights and
       retention of other rights under this Loan Agreement  notwithstanding that
       the Note may be assigned or otherwise  transferred by the Lender), at any
       time  and  from  time to time.  The  Company  may not  assign  this  Loan
       Agreement  or any of its  rights or duties  hereunder  or under the Note,
       without the prior written consent of the Lender.



















                                       10


<PAGE>



         IN WITNESS WHEREOF,  the parties hereto cause this Loan Agreement to be
duly executed as of the date first above written.

                                        LENDER

                                        SEAFIELD CAPITAL CORPORATION

                                        By: /s/   James R. Seward
                                            ------------------------------
                                        Name:    James R. Seward
                                        Title:   EVP Chief Financial Officer


                                        COMPANY

                                        RESPONSE ONCOLOGY, INC.

                                        By: /s/    Joseph P. Clark
                                            ------------------------------- 
                                        Name:    Joseph P. Clark
                                        Title:   President
































                                       11


<PAGE>






















































<PAGE>

                                                                    EXHIBIT 99.2


THIS NOTE HAS BEEN ACQUIRED FOR INVESTMENT AND HAS NOT BEEN REGISTERED UNDER THE
SECURITIES  ACT OF 1933, AS AMENDED,  AND MAY NOT BE OFFERED,  SOLD OR OTHERWISE
TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION  UNLESS RESPONSE ONCOLOGY,  INC.
HAS  BEEN  FURNISHED  AN  OPINION  OF  COUNSEL  SATISFACTORY  TO  IT  THAT  SUCH
TRANSACTION WILL NOT VIOLATE SUCH REGISTRATION REQUIREMENTS.

THIS NOTE IS SUBJECT TO THE PROVISIONS OF THAT CERTAIN SUBORDINATION  AGREEMENT,
DATED OCTOBER 4, 1996, AMONG RESPONSE ONCOLOGY,  INC., NATIONSBANK OF TENNESSEE,
N.A., AS AGENT, AND SEAFIELD CAPITAL CORPORATION.


                             RESPONSE ONCOLOGY, INC.
NO. 1996A-1                                                      $23,500,000
                        ADJUSTABLE RATE CONVERTIBLE NOTE
                               DUE AUGUST 31, 1998
                              Dated October 4, 1996

         For value received,  RESPONSE ONCOLOGY,  INC., a Tennessee  corporation
(the  "Company"),  hereby  promises to pay to SEAFIELD  CAPITAL  CORPORATION,  a
Missouri corporation ("Seafield"),  or its registered assigns, the principal sum
of TWENTY-THREE  MILLION FIVE HUNDRED  THOUSAND DOLLARS  ($23,500,000),  or such
lesser  amount of principal as is  outstanding  under this Note,  together  with
interest on the unpaid principal portion thereof, as herein provided.

         The principal amount of this Note, together with any accrued and unpaid
interest  thereon,  shall be payable in full on the  earliest  of (i) August 31,
1998 (ii) the first date prior to January 1, 1997 on which the Company  receives
proceeds  from  an  offering  or  other  sale of its  Capital  Stock  or  Senior
Subordinated  Indebtedness,  or (iii) such date after  December  31,  1996 as is
specified by the Holder,  provided that such date is on or after a date on which
the Company  receives  proceeds  from an offering of its Capital Stock or Senior
Subordinated  Indebtedness.  Payments under (ii) and (iii) may be made only from
the proceeds of such offering or sale.

         Principal of this Note shall bear interest  from the date  principal is
advanced  at a rate per annum  equal to the Note Rate as in effect  from time to
time. Interest on this Note shall be paid on the last day of each quarter (i.e.,
December  31,  March  31,  June 30 and  September  30) and at  maturity  or upon
redemption or conversion.  Interest hereunder shall be calculated for the actual
number of days elapsed on the basis of a year consisting of 360 days.

         Such  principal and interest  payments  shall be made to Seafield or to
such other person in whose name this Note is registered  (Seafield or such other
person being  referred to as the  "Holder") on the  register  maintained  by the
Secretary  of the  Company  ("Note  Register")  at the close of  business 










<PAGE>

on  the  "Record   Date"  for  such  principal  and interest  installment.  Such
Record  Date  shall  be  the  fifth  day  (whether  or  not a Business Day) next
preceding  such  principal and interest payment date.

         Payment of the  principal  of and interest on this Note will be made to
the  Holder  at the  Principal  Executive  Office  of the  Company  in  Memphis,
Tennessee,  in such coin or currency  of the United  States of America as at the
time of  payment  is legal  tender for  payment  of public  and  private  debts;
provided,  however,  that at the  request  of the  Holder  made on or before the
Record Date  payment may be made by check mailed to the address of the Holder as
such address shall appear in the Company's  Note Register or by wire transfer to
such account as may be specified to the Company in writing by the Holder.

         This Note is that  certain  promissory  note  referred to in and issued
pursuant to the Loan  Agreement  dated October 4, 1996,  between the Company and
Seafield  and this Note is entitled to the  benefit of said Loan  Agreement,  to
which reference is hereby made for a statement of the terms and conditions under
which  the  loan  evidenced  hereby  is made.  This  Note is  designated  as the
Company's  Adjustable Rate  Convertible  Note, No. 1996A-1,  due August 31, 1998
(the "Note") and when issued was in the principal  amount of  $23,500,000.  This
Note is convertible as provided in Section 3 hereof.

         The books and records of the Holder shall be presumptive  (i) as to the
amount  and  date of each  advance  of  monies  hereunder  and  under  the  Loan
Agreement,  and (ii) as to the amount from time to time of the unpaid  principal
amount of this Note.

         This Note was originally  issued to fund the acquisition by the Company
of the New  Oncology  Practices,  as herein  defined,  and to fund $3 million of
Company working capital.

The following terms apply to this Note:

         SECTION 1.  Certain Definitions.

         As used in this Note:

         "Affiliate" means (i) with respect to any specified Person,  any Person
directly or indirectly  controlling or controlled by or under direct or indirect
common  control with such  specified  Person.  For purposes of this  definition,
"control"  when used with  respect to any  specified  Person  means the power to
direct the  management  and  policies of such  Person,  directly or  indirectly,
whether through the ownership of voting stock, by contract or otherwise; and the
terms "controlling" and "controlled" have meanings correlative to the foregoing.

         "Boca   Assumed   Debt"   means   Indebtedness   of  The   Center   for
Hematology-Oncology,  P.A.,  a  Florida  professional  association,  aggregating
$76,000,  assumed by the Company as partial payment of the acquisition price for
assets of said professional association.






                                       2


<PAGE>



         "Business  Day" means each  Monday,  Tuesday,  Wednesday,  Thursday and
Friday which is not a day on which banking  institutions in the City of New York
are authorized or obligated by law or executive order to close.

         "Capital  Lease"  means any lease of  property,  real or  personal,  in
respect of which the present  value of the minimum  rental  commitment  would be
capitalized  on a balance  sheet of the  lessee  in  accordance  with  generally
accepted accounting principles;  provided that any such lease will not be deemed
a  Capital  Lease  for  purposes  of this  Note  or the  Loan  Agreement  if the
obligations and rental commitments  thereunder do not or will not exceed $25,000
in any year and if the aggregate of the obligations and rental commitments under
all such leases do not or will not exceed $500,000 in any year.

         "Capital  Stock" of any  Person  means any and all  shares,  interests,
participations or other equivalents  (however  designated) of corporate stock of
such Person.

         "Common  Stock" means the Company's  Common Stock,  par value $ .01 per
share, or any shares of Capital Stock of the Company into which such stock shall
hereafter be changed or reclassified.

         "Credit  Facility" means the credit facility provided for in the Senior
Debt Agreements, as that term is defined in the Subordination Agreement.

         "Indebtedness" of any Person means (i) any liability of such Person (a)
for borrowed  money,  (b) evidenced by a note,  debenture or similar  instrument
(including a purchase money obligation or deferred payment  obligation) given in
connection with the acquisition of any services,  property or assets (other than
inventory, other accrued current liabilities or similar property acquired in the
ordinary  course of  business),  including  securities  (but  excluding  reverse
repurchase agreements entered into in the ordinary course of business),  (c) for
the payment of a Capital Lease  obligation of such person or (d) with respect to
the reimbursement of any letter of credit, banker's acceptance or similar credit
transaction (other than trade letters of credit issued in the ordinary course of
business;  provided,  that  failure to make  prompt  reimbursement  of any trade
letter of credit shall be deemed to be the incurrence of Indebtedness); (ii) any
guarantee  by such Person of any  liability  of others  described  in clause (i)
above or any  obligation  of such Person with respect to any liability of others
described in clause (i) above,  including  liability of others secured by a lien
on the property of such Person, whether or not the liability so secured has been
assumed by such Person;  and (iii) all Interest Rate  Protection  Obligations of
such Person.  Indebtedness  shall not include operating leases or trade accounts
payable.

         "Interest Rate  Protection  Obligations"  means the  obligations of any
Person  pursuant to any arrangement  with any other Person whereby,  directly or
indirectly,  such  Person is  entitled  to  receive  from time to time  periodic
payments calculated by applying either a floating or a fixed rate of interest on
a stated notional  amount in exchange for periodic  payments made by such Person
calculated  by  applying  a fixed or a  floating  rate of  interest  on the same
notional amount and shall include without limitation, interest rate swaps, caps,
floors, collars and similar agreements.

                                       3


<PAGE>


         "Knoxville  Assumed Debt" means  Indebtedness of the Knoxville Oncology
Practice  under Capital Lease  obligations  aggregating  $93,475  assumed by the
Company as partial  payment of the acquisition  price of the Knoxville  Oncology
Practice.

         "Knoxville  Oncology  Practice"  means  Knoxville   Hematology-Oncology
Associates, whose principal business office is located in Knoxville, Tennessee.

         "Loan Agreement" means the Loan Agreement dated October 4, 1996 between
the Company and Seafield, pursuant to which this Note has been issued.

         "New Oncology  Practices" means Weinreb,  Weisberg & Weiss, M.D., P.A.;
Drs. Antonucci,  McCormack,  Haraf & Kerns;  Hematology Oncology of the Treasure
Coast, P.A.; The Center for Hematology-Oncology,  P.A.; and Lawrence A. Snetman,
M.D., P.A.

         "Note Rate" means,  at all times prior to April 1, 1997,  eight percent
(8%) per annum; at all times after March 31, 1997 and prior to July 1, 1997, ten
percent (10%) per annum;  and at all times after June 30, 1997,  twelve  percent
(12%) per annum.

         "pari passu" when used with respect to the ranking of any  indebtedness
of any Person in relation to other Indebtedness of such Person,  means that each
such  indebtedness (a) either (i) is not subordinated in right of payment to any
other  Indebtedness of such Person or (ii) is subordinate in right of payment to
the same  Indebtedness  of such Person as is the other and is so  subordinate to
the same extent,  and (b) is not subordinate in right of payment to the other or
to any Indebtedness of such Person as to which the other is not so subordinate.

         "Person" means an individual, corporation,  partnership, joint venture,
trust,   unincorporated  organization  or  government  or  agency  or  political
subdivision thereof.

         "Physician  Assumed  Debt" means the Knoxville  Assumed Debt,  the Boca
Assumed Debt and the Weinreb, Weisberg & Weiss Assumed Debt.

         "Physician  Notes"  means (i) the note  payable to the  partners of the
Knoxville  Oncology  Practice,  in the principal amount of $150,000,  as partial
payment  of the  acquisition  price  therefor,  (ii)  the  note  payable  to the
shareholders  of  Oncology  Hematology  Group of  South  Florida,  P.A.,  in the
principal  amount of $5,959,972,  as partial  payment of the  acquisition  price
therefor, (iii) the note payable to the shareholders of St. Petersburg Oncology,
Inc.,  in  the  principal  amount  of  $5,100,000,  as  partial  payment  of the
acquisition  price  therefor,  (iv)  the note  payable  to the  shareholders  of
Rosenberg & Kalman,  M.D.,  P.A.,  in the  principal  amount of  $1,900,000,  as
partial payment of the acquisition  price therefor,  (v) the note payable to the
shareholders of Weinreb,  Weisberg & Weiss,  M.D., P.A., in the principal amount
of $417,812, as partial payment of the acquisition price therefor, (vi) the note
payable to the partners of Drs. Antonucci, McCormack, Haraf & Kerns, a Tennessee
partnership,  in the  principal  amount of $725,000,  as partial  payment of the
acquisition  price  therefor,  (vii) the note  payable  to the  shareholders  of
Hematology  Oncology of the Treasure  Coast,  P.A., in the  principal  amount of
$1,362,500, as partial payment of the acquisition price therefor, (viii) the

                                       4


<PAGE>



note  payable to The  Center for  Hematology-Oncology,  P.A.,  in the  principal
amount of $4,000,000, as partial payment of the acquisition price for the assets
thereof,  and (ix) the note payable to the  shareholders of Lawrence A. Snetman,
M.D.,  P.A.,  in the  principal  amount of  $90,000,  as partial  payment of the
acquisition price therefor.



         "Principal Executive Office" means 1775 Moriah Woods Boulevard, 
Memphis, Tennessee 38117.

         "Recapitalization  Plan"  means  a plan  submitted  to the  Company  by
Seafield  for the  recapitalization  of the  Company's  Capital  Stock which (i)
provides (A) that the Capital Stock of the Company owned by Seafield immediately
after consummation of the recapitalization  which was derived from Capital Stock
of the Company which immediately before consummation of the recapitalization had
been owned by  Seafield  for at least 5 years  would  constitute  Capital  Stock
possessing  at least 80% of the total  combined  voting  power of all classes of
Capital Stock of the Company  entitled to vote and (B) that the Company will not
have  authorized or outstanding any shares of a class of Capital Stock which are
not Voting  Stock,  and (ii) makes no changes in the  capital  structure  of the
Company except as necessary to accomplish  the  foregoing.  For purposes of this
definition,  "Capital  Stock" shall have the same meaning as the term "stock" in
Section 368(c) of the Internal Revenue Code of 1986, as amended (the "Code") and
percentages of voting power shall be determined in a manner  consistent with the
requirements of Section 355 of the Code.

         "Required  Approvals"  means all  approvals  required  under  state and
federal laws,  rules or regulations or under rules of applicable  regulatory and
self-regulatory  agencies  or  bodies  to  enable  the  Company  to  effect  the
Recapitalization Plan.

         "Senior  Subordinated  Indebtedness"  means Indebtedness of the Company
which is  subordinated  in right of  payment  to any other  Indebtedness  of the
Company  unless such  Indebtedness  is either  evidenced by one of the Physician
Notes or is also subordinated in right of payment,  in a manner  satisfactory to
the Holder, to the Indebtedness evidenced by this Note.

         "Shareholder Approval" means approval by the holders (including without
limitation  Seafield) of a majority of the issued and outstanding  shares of the
Company's  Common Stock (i) of a change in the  Conversion  Price (as defined in
Section 3 hereof) to $11.00 and the  issuance of shares of Company  Common Stock
pursuant to the Conversion  Privilege contained in Section 3 hereof based upon a
Conversion Price of $11.00, and (ii) of the issuance of the Warrant provided for
in Section 5(d) of the Loan  Agreement and shares of the Company's  Common Stock
in connection  with one or more exercises of said Warrant  pursuant to the terms
thereof.

         "Subordination  Agreement"  means  the  Subordination  Agreement  dated
October 4, 1996, among the Company, Seafield and NationsBank of Tennessee, N.A.,
as Agent.


                                       5


<PAGE>



         "Subsidiary"  means a  corporation  more  than  50% of the  outstanding
Voting Stock of which is owned, directly or indirectly, by the Company or by one
or more other Subsidiaries and which is a "significant subsidiary" as defined in
Rule 1-01 (w) of Regulation S-X of the Securities and Exchange Commission.

         "Voting  Stock" of any Person means  Capital Stock of such Person which
ordinarily has voting power for the election of directors (or persons performing
similar  functions)  of such Person,  whether at all times or only so long as no
senior class of stock has such voting power by reason of any contingency.

         "Warrant  Issuance  Event"  means  any of  the  following,  unless  all
principal  of and  interest on the Note is paid in full prior to January 1, 1997
and  simultaneously  therewith  909,000 shares of the Company's Common Stock are
purchased  from Seafield at a price per share of $11.00:  (i) the failure by the
Company to file with the Securities and Exchange Commission within 30 days after
the later of (A) the  earlier  of (x) the date upon which the  principal  of and
interest on this Note is paid in full,  and (y) January 1, 1997 and (B) the date
upon  which  Seafield  submits to the  Company in writing a request  for and the
terms of a  Recapitalization  Plan (such later date being the "Notice Date"),  a
preliminary proxy statement  providing for, among other things, a meeting of the
Company's  shareholders,  to be held not later  than 120 days  after the  Notice
Date, for the purpose of obtaining all Required  Approvals by said  shareholders
(including  shareholders other than Seafield) of the  Recapitalization  Plan; or
(ii)  the  failure  by the  Company's  Board  of  Directors  to  unconditionally
recommend the Recapitalization Plan by way of a statement of such recommendation
in the  definitive  proxy  statement and other  materials  sent to the Company's
shareholders in connection with the shareholders meeting contemplated herein; or
(iii) any change in or withdrawal of the recommendation of the  Recapitalization
Plan by the Company's Board of Directors after the date of the definitive  proxy
statement;  or (iv) a failure to hold the contemplated  meeting of the Company's
shareholders by the 120th day following the Notice Date.

         "Weinreb, Weisberg & Weiss Assumed Debt" means Indebtedness of Weinreb,
Weisberg  & Weiss,  M.D.,  P.A.,  under  Capital  Note  obligations  aggregating
$13,000,  assumed by the Company as partial payment of the acquisition  price of
Weinreb, Weisberg & Weiss, M.D., P.A., located in Tamarac, Florida.

         SECTION 2.  Limitation on Other  Indebtedness.  Neither the Company nor
any Subsidiary of the Company will issue, assume,  guarantee or otherwise become
liable for, directly or indirectly,  or suffer to exist, any Indebtedness unless
(i) such  Indebtedness  (other than the Physician Notes,  the Physician  Assumed
Debt,  and borrowings  under the Credit  Facility) is  subordinated  in right of
payment  to this  Note in a manner  satisfactory  to the  Holder  and (ii)  such
Indebtedness  (other than the Physician  Assumed Debt and  borrowings  under the
Credit Facility) is unsecured. The Company covenants that Indebtedness under the
Physician  Notes and the  Physician  Assumed Debt is or when issued will be pari
passu in right  of  payment  with  Indebtedness  under  this  Note  except  that
Indebtedness  under the Physician Assumed Debt may remain secured by property of
the Knoxville Oncology Practice to the extent so secured on April 1, 1996 and by
property of one or more of the



                                       6


<PAGE>



New  Oncology  Practices,  to the extent so  secured on the date a New  Oncology
Practice is acquired by the Company or a Subsidiary of the Company.

         SECTION 3.  Conversion Rights.

                  (a) The Holder shall have the option,  exercisable  in writing
at any time  until the time this Note is paid in full or  redeemed  in full (and
whether this Note has been called for  redemption  prior to the exercise of such
option)  to  convert  this Note in its  entirety  or in part into  shares of the
Company's  fully paid and  non-assessable  Common Stock at the conversion  price
determined as provided  herein (the  "Conversion  Price".) Upon the surrender of
this  Note,  accompanied  by a  conversion  notice in the form  attached  hereto
properly completed and duly executed by the Holder (a "Conversion Notice"),  the
Company shall issue and, within three business days after such surrender of this
Note with the Conversion Notice,  deliver to or upon the order of the Holder (i)
that  number  of shares of Common  Stock as shall be  determined  in  accordance
herewith and (ii) payment of the accrued and unpaid interest on the part of this
Note which is the  subject  of the  Conversion  Notice.  The number of shares of
Common Stock to be issued upon  conversion  of this Note or a part thereof shall
be determined by dividing the principal  amount of the Note to be converted,  as
specified in the Conversion  Notice,  by the  Conversion  Price in effect on the
date the  Conversion  Notice is delivered by the Holder to the  Secretary of the
Company at its Principal Executive Office; provided that if the number of shares
of Common Stock so to be issued would be equal to or exceed 20% of the number of
shares  of  Common  Stock  outstanding  at the time  the  Conversion  Notice  is
delivered ("20% of the Outstanding Shares"),  then the Conversion Notice will be
deemed to be  modified so as to specify an amount of  principal  of the Note for
conversion  which  would  result in the  issuance  by the Company of the largest
number  of  shares of  Common  Stock  which is less than 20% of the  Outstanding
Shares.  The Holder  shall be  entitled  to all rights of a  shareholder  of the
Company as of such date.

                  (b) The  Conversion  Price  shall be the highest bid price for
the  Company's  Common  Stock at the close of  trading on the last  trading  day
before a Conversion  Notice is  delivered by the Holder to the  Secretary of the
Company,  as posted on the National  Association of Securities Dealers automated
quotation  system;  provided  that  after  December  31,  1996,  subject  to the
Shareholder Approval, the Conversion Price shall be $11.00. The Conversion Price
will be appropriately  adjusted to eliminate the impact of any dividend or other
distribution   (whether  in  cash,   securities  or   property),   stock  split,
reclassification,  recapitalization,  reverse  stock split or similar  event the
record  date for  which is after  the date of this  Note and prior to the date a
Conversion Notice is received by the Company.

                  (c) If pursuant to the Conversion Notice, the Holder elects to
convert  less than all of the Note,  the  Company  will issue a new Note of like
tenor to the Holder for the unconverted portion hereof, with appropriate changes
to reflect the reduced principal amount after giving effect to such conversion.

                  (d) The Company covenants that during the period the foregoing
conversion  right  exists,  the Company  will reserve  from its  authorized  and
unissued Common Stock a sufficient

                                       7


<PAGE>



number of shares to provide for the issuance of Common Stock upon the conversion
of this Note or any part thereof.  The Company  represents  that upon  issuance,
such shares will be duly and validly issued, fully paid and non-assessable.  The
Company agrees that its issuance of this Note shall constitute full authority to
its  officers  and  agents  who are  charged  with the duty of  executing  stock
certificates  to  execute  and issue the  necessary  certificates  for shares of
Common Stock upon the conversion of this Note or any part thereof.

                  (e) Except as otherwise provided in this Note or agreed by the
Holder,  this  Note may be  converted  by the  Holder by (i)  submitting  to the
Borrower  a  Conversion  Notice  in the  form  attached  to this  Note  and (ii)
surrendering this Note at the Principal Executive Office of the Company.

                  (f) The Shares of Common Stock issuable upon the conversion of
this Note or any part thereof may not be sold or  transferred  unless either (i)
they first  shall have been  registered  under the  Securities  Act ot 1933,  as
amended (the "Act") and  applicable  state  securities  laws or (ii) the Company
shall  have been  furnished  with an  opinion of legal  counsel  experienced  in
securities   laws  matters  (which  counsel  and  opinion  shall  be  reasonably
acceptable  to the  Company)  to the effect that such sale or transfer is exempt
from  the  registration  requirements  of  the  Act  and  all  applicable  state
securities  laws.  Each  certificate  for shares of Common Stock  issuable  upon
conversion of this Note that have not been so registered  and that have not been
sold pursuant to an exemption that permits  removal of the legend,  shall bear a
legend substantially in the following form, as appropriate:


    THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED
    UNDER THE SECURITIES ACT OF 1933, AS AMENDED.  THE SECURITIES HAVE BEEN
    ACQUIRED FOR INVESTMENT AND MAY NOT BE SOLD, TRANSFERRED OR ASSIGNED IN
    THE ABSENCE OF AN EFFECTIVE  REGISTRATION  STATEMENT FOR THE SECURITIES
    UNDER THE SECURITIES ACT OF 1933, AS AMENDED,  OR AN OPINION OF COUNSEL
    THAT REGISTRATION IS NOT REQUIRED UNDER SAID ACT.

Upon the request of a holder of a certificate  representing any shares of Common
Stock  issuable  upon  conversion  of this Note,  the Company  shall  remove the
foregoing  legend from the certificate or issue to such holder a new certificate
therefor,  free of any transfer legend, if, with such request, the Company shall
have received  either (i) an opinion of counsel  experienced in securities  laws
matters (which counsel and opinion are reasonably  acceptable to the Company) to
the effect that any such legend may be removed from such certificate, or (ii) if
the present paragraph (k) of Rule 144 or a substantially  similar successor rule
remains in force and effect,  satisfactory  representations from the holder that
such holder is not then, and has not been during the preceding three (3) months,
an affiliate  of the Company,  and that a period of at least three (3) years has
elapsed since the later of the date the securities  were acquired (as determined
under Rule 144) from the Company or an affiliate of the Company.






                                       8


<PAGE>

         SECTION 4. Events of Default. "Event of Default", wherever used herein,
means any one of the  following  events  (whatever  the reason for such Event of
Default  and  whether it shall be  voluntary  or  involuntary  or be effected by
operation  of law or pursuant to any  judgment,  decree or order of any court or
any order, rule or regulation of any administrative or governmental body):

                  (a) default in the payment of any interest upon this Note when
it becomes due and payable,  and  continuance  of such default for a period of 5
days;

                  (b)  default in the payment of the principal of this Note when
due and payable;

                  (c)  failure by the  Company to use  substantially  all of the
proceeds of any advance under this Note and the Loan Agreement to acquire one or
more of the New  Oncology  Practices;  provided  that  up to  $3,000,000  of the
Indebtedness  evidenced by this Note may be used for general  working capital of
the Company;

                  (d)  failure by the  Company to issue to the Holder the number
of shares of Common Stock issuable upon exercise by the Holder of the conversion
rights of the Holder in accordance with the terms of this Note;

                  (e)  the occurrence of an Event of Default under the Loan 
Agreement;

                  (f) default in the performance,  or breach, of any covenant or
agreement  of  the  Company  under  this  Note  (other  than  a  default  in the
performance,  or breach,  of a covenant or agreement that is specifically  dealt
with elsewhere in this Section), and continuance of such default or breach for a
period of  thirty  (30)  days  after  there has been  given,  by  registered  or
certified  mail, to the Company by the Holder a written notice  specifying  such
default or breach and stating that such notice is a "Notice of Default";

                  (g) (i) an event of  default  shall  have  occurred  under any
mortgage,  bond,  indenture,  loan  agreement or other  document  evidencing any
Indebtedness  of the  Company  or  any  Subsidiary  for  money  borrowed,  which
Indebtedness  has an  aggregate  outstanding  principal  amount of not less than
$500,000, and such default shall result in such Indebtedness  becoming,  whether
by declaration or otherwise, due and payable prior to the date on which it would
otherwise  become due and payable or (ii) a default in any  payment  when due at
final  stated  maturity of any such  Indebtedness  outstanding  in an  aggregate
principal  amount of not less than $500,000 and, in each case, ten (10) Business
Days shall have  elapsed  after such event  during which period such event shall
not have  been  cured or  rescinded  or such  Indebtedness  shall  not have been
satisfied;

                  (h) final judgments or orders shall have been rendered against
the  Company or any  Subsidiary  by a court or  regulatory  agency of  competent
jurisdiction  which require the payment in money,  either  individually or in an
aggregate  amount,  that is more than $ 500,000  (other than any  judgment as to
which a  reputable  insurance  company has  accepted  full  liability)  and such
judgment or order shall not be discharged and either (i) any creditor shall have
commenced  an  enforcement   proceeding  upon  such  judgment  or  order,  which
enforcement proceeding shall have remained
                                       9


<PAGE>

unstayed  for a period of ten (10)  days,  or (ii) a period  of sixty  (60) days
during  which a stay of  enforcement  shall not be in effect  shall have elapsed
following the date on which any period for appeal has expired;

                  (i) a decree  or order  shall  have  been  entered  by a court
having jurisdiction for relief in respect of the Company or any Subsidiary in an
involuntary  case or proceeding  under the Federal  Bankruptcy Code or any other
federal  or state  bankruptcy,  insolvency,  reorganization  or  similar  law or
adjudging  the Company or any  Subsidiary  a bankrupt or  insolvent,  or seeking
reorganization,  arrangement,  adjustment or composition of or in respect of the
Company  or any  Subsidiary  under  the  Federal  Bankruptcy  Code or any  other
applicable   federal  or  state  law,  or  appointing  a  custodian,   receiver,
liquidator,  assignee, trustee,  sequestrator (or other similar official) of the
Company or any Subsidiary or of any substantial part of any of their properties,
or ordering the winding up or liquidation of any of their affairs,  and any such
decree  or order  remains  unstayed  and in effect  for a period  of sixty  (60)
consecutive days; or

                  (j) the  Company or any  Subsidiary  shall have  instituted  a
voluntary  case or  proceeding  under the Federal  Bankruptcy  Code or any other
applicable  federal  or  state  law or  any  other  case  or  proceedings  to be
adjudicated a bankrupt or insolvent, or the Company or any Subsidiary shall have
consented to the entry of a decree or order for relief in respect of the Company
or any  Subsidiary  in any  involuntary  case or  proceeding  under the  Federal
Bankruptcy  Code  or  any  other  applicable  federal  or  state  law  or to the
institution of bankruptcy or insolvency  proceedings  against the Company or any
Subsidiary,  or the  Company or any  Subsidiary  shall have filed a petition  or
answer or consent seeking  reorganization or relief under the Federal Bankruptcy
Code or any other applicable federal or state law, or consented to the filing of
any such petition or to the appointment of or taking  possession by a custodian,
receiver,   liquidator,   assignee,  trustee,  sequestrator  (or  other  similar
official) of any of the Company or any Subsidiary or of any substantial  part of
its property, or shall have made an assignment for the benefit of creditors,  or
admitted in writing its inability to pay its debts  generally as they become due
or taken corporate action in furtherance of any such action;

Upon  the  occurrence  of an  Event of  Default,  then,  in the case of an event
described  in (i) or (j)  above,  this Note  shall  immediately  become  due and
payable,  together  with  interest  accrued  hereon or, in the case of any other
event described  above,  the Holder of the Note may declare this Note,  together
with  all  interest  accrued  hereon  to be  due  and  payable  and,  upon  such
declaration,  this Note together with accrued  interest  hereon shall be due and
payable  on the  date  specified  in  the  declaration,  in  each  case  without
presentment,  demand,  protest  or other  notice of any  kind,  all of which are
hereby  waived by the  Company.  The  holder of this  Note may also  proceed  to
protect and enforce its rights either by suit in equity and/or by action at law,
or by other  appropriate  proceedings,  or may proceed to enforce the payment of
this Note or to enforce any other legal or equitable right of the Holder of this
Note, including its right to convert this Note.

         SECTION 5.  Registration  of Transfers.  The Company shall register the
transfer  of this Note upon  records to be  maintained  by the  Company for that
purpose,  upon  surrender  of this Note,  with the Form of  Assignment  attached
hereto duly filled in and signed, and, if the transfer is prior to

                                       10


<PAGE>



January 1, 1997, with the Form of Assumption  attached hereto duly signed by the
transferee, to the Secretary of the Company at the Company's Principal Executive
Offices.  Any such request for  transfer  must be  accompanied  by an opinion of
counsel  satisfactory  to the Company  that such  transfer  will not violate the
registration  requirements  of  the  Securities  Act  of  1933.  Upon  any  such
registration of transfer,  a new Note, in  substantially  the form of this Note,
evidencing the Note so transferred, shall be issued to the transferee.

         SECTION 6.  Payment of Taxes.  The Company shall not be required to pay
any tax in respect of the transfer of the Note.

         SECTION 7.  Redemption.  The Note is subject to complete  redemption at
the option of the  Company,  at any time  prior to April 1, 1997,  upon not less
than 20 nor more than 40 days' written  notice,  at a redemption  price equal to
100% of the principal amount of this Note together with accrued interest on this
Note to the redemption  date. This Note is not subject to partial  redemption at
any time,  and is not subject even to complete  redemption  at the option of the
Company after March 31, 1997.


         This Note does not have the benefit of any sinking fund obligations.

         SECTION 8.  Mutilated or Missing Note. If this Note shall be mutilated,
lost, stolen or destroyed,  upon request by the Holder hereof,  the Company will
issue,  in exchange  for and upon  cancellation  of the  mutilated  Note,  or in
substitution   for  the  lost,   stolen  or  destroyed  Note,  a  new  Note,  in
substantially  the form of this Note,  of like tenor and maturity and having the
same principal amount, but, in the case of loss, theft or destruction, only upon
receipt  of  evidence  satisfactory  to the  Company  of  such  loss,  theft  or
destruction of this Note and, if requested by the Company,  indemnity reasonably
satisfactory to it.

         SECTION 9.  Restriction on Transfer.

                  (a) This Note shall not be transferred  unless the Company has
been furnished an opinion of counsel  satisfactory  to it that such  transaction
will not violate the  registration  provisions of the  Securities Act of 1933 or
any applicable state securities law.

                  (b) This Note may not be transferred  prior to January 1, 1997
unless the proposed  transferee  assumes in writing the  obligations of Seafield
under the Loan Agreement to advance funds as set forth in the Loan Agreement.

                  (c) This Note and each Note issued  upon  transfer or exchange
shall bear a legend (the "Restrictive  Legend") as to the restrictions on resale
contained or provided for in this Section 9 in substantially  the form set forth
at the beginning of this Note.






                                       11


<PAGE>



         SECTION 10. Financial Information.  Until this Note is paid in full, if
at any time the Company  ceases to be a reporting  company under the  Securities
Exchange Act of 1934, the Company agrees to furnish to the registered Holder, at
the address  specified in the Note Register,  within  forty-five (45) days after
the end of each quarter, a copy of the Company's  quarterly  unaudited financial
statements,  and  within  one  hundred  twenty  (120)  days after the end of the
Company's  fiscal  year, a copy of the  Company's  annual  audited  consolidated
financial statements.

         SECTION  11.  Notices.  All  notices,   requests,   demands  and  other
communications  relating  to the Note shall be in writing,  including  by telex,
telegram or cable,  addressed, if to the registered holder hereof, to it or them
at the address(es) furnished by said registered holder(s) to the Company, and if
to the Company, to it at the Principal Executive Office,  Attention:  Secretary,
or to such other  address as any party shall  notify the other party in writing,
and,  except as provided in Section  3(a),  shall be  effective,  in the case of
written  notice by mail,  upon  placement  into the mails (first class,  postage
prepaid),  and in the case of  notice by telex,  telegram  or cable,  on the day
sent.

         SECTION 12. Binding  Effect.  This Note shall be binding upon and inure
to the sole and exclusive  benefit of the Company,  its  successors and assigns,
and the registered holder or holders from time to time of this Note.

         SECTION 13.  Survival of Rights and Duties.  This Note shall  terminate
and be of no further force and effect on the date the  principal  hereof and all
interest hereon shall have been paid in full.

         SECTION 14.  Governing Law.  This Note shall be construed in accordance
with and governed by the internal laws of the State of Missouri.

         IN WITNESS  WHEREOF,  the  Company  has caused this Note to be executed
under its corporate  seal by its officers  thereunto  duly  authorized as of the
date hereof.

                                           RESPONSE ONCOLOGY, INC.


[CORPORATE SEAL]
                                            By: ____________________________
                                                  Joseph P. Clark
                                                  President and Chief  Executive
ATTEST:                                           Officer


_____________________________
          Secretary






                                       12


<PAGE>
                               FORM OF ASSIGNMENT

     FOR  VALUE  RECEIVED,  ________________________ hereby sells,  assigns  and
transfers to the  assignee set forth below all of the rights of the  undersigned
in and to this Note:

            Name of Assignee                   Address


                                                Name of Holder


                                                _______________________________

Dated:__________________, 199__                 By: ___________________________

                                                Title: -----------------------

                               FORM OF ASSUMPTION

         In  consideration  of the transfer to it of this Note, the  undersigned
transferee hereby assumes and agrees to perform all remaining obligations of the
Lender  under  the  Loan  Agreement  to  advance  monies.  The  transferee,  the
transferor  and the Company each  acknowledge  that the amount of such remaining
obligations is $ ______________________.
                 

                                                Name of Transferee

Dated: _________________________                ______________________________ 
       
                                                By: __________________________
                                                   
                                                Title: _______________________
                                                       


                                                Name of Transferor

                                                ______________________________

Dated: _________________________                By: __________________________
     
                                                Title: _______________________
                                                       


                                                RESPONSE ONCOLOGY, INC.


Dated: _________________________                By: __________________________
      
                                                Title: _______________________
                                                       


                                       13


<PAGE>


                                CONVERSION NOTICE

To Response Oncology, Inc.

         The undersigned Holder of this Note irrevocably exercises the option to
convert  either all of this Note,  or the portion  noted  below,  into shares of
Common Stock of Response  Oncology,  Inc. in  accordance  with the terms of this
Note, and directs that the shares issuable and deliverable  upon the conversion,
together  with any  check in  payment  for  fractional  shares,  be  issued  and
delivered to the registered Holder of this Note unless a different name has been
indicated  below.  If shares are to be issued in the name of a person other than
the  undersigned,  the  undersigned  will pay all  transfer  taxes  payable with
respect thereto.

            Convert the entire principal              Name Of Holder
_________   amount of this Note

            Convert $ __________ of the               _________________________
_________   principal of this Note, and issue         By: _____________________
            a new Note for the unconverted            Title: __________________
            portion, in accordance with Section
            3(c) of this Note

Dated ________________, 19__
     



         Fill in for  registration  of shares  of  Common  Stock if to be issued
otherwise than to the registered Holder.

________________________________           ____________________________________
Name of Person to Whom  Shares             (Social  Security  or Other  Taxpayer
are to be issued and payment for           Identifying  Number)  
fractional shares is to be made (if
other than registered holder)


_________________________________
Address including zip code number














                                       14


<PAGE>






















































<PAGE>

                                                                    EXHIBIT 99.3


                              SUBORDINATION AGREEMENT


         THIS  SUBORDINATION  AGREEMENT  ("Agreement") is entered into as of the
4th day of October, 1996, by and among RESPONSE ONCOLOGY,  INC. ("Borrower"),  a
Tennessee  corporation;  NATIONSBANK OF TENNESSEE,  N.A.  ("Agent"),  a national
banking  association,  in its capacity as Agent for the "Lenders," as defined in
that Loan Agreement  dated as of May 31, 1996,  among  Borrower,  Union Planters
National Bank, a national  banking  association,  and  NationsBank of Tennessee,
N.A.,  as such Loan  Agreement  may be amended  from time to time:  and SEAFIELD
CAPITAL CORPORATION ("Subordinated Lender"), a Missouri corporation.

                                     RECITALS:

         WHEREAS, Senior Lenders (as defined below) and Subordinated Lender have
both  extended  or agreed to extend  credit to  Borrower,  on certain  terms and
conditions; and

         WHEREAS, one condition to Senior Lenders' agreement to extend credit to
Borrower is that  Subordinated  Lender must agree that  certain  obligations  of
Borrower to  Subordinated  Lender shall be  subordinate  to the  obligations  of
Borrower to Senior Lenders on the terms set forth in this Agreement.

         NOW, THEREFORE,  in consideration of the premises;  as an inducement to
cause  Senior  Lenders  to extend  credit to  Borrower;  and for other  valuable
consideration,  the receipt and  sufficiency  of which are  acknowledged,  it is
agreed as follows:

         1.   DEFINITIONS.  As used below in this Agreement, the following 
capitalized terms have the meanings set forth below:

                  "Acquisition Debt" means obligations of the Borrower to either
(i) one or more of the  entities  engaged  in a medical  practice  the assets of
which have been acquired by the Borrower or one of its  Affiliates,  or (ii) the
owners or former owners of such practice.

                  "Affiliate" means, with respect to any Person, a second Person
that, directly or indirectly,  (i) owns a majority of the equity interest in the
first  Person,  (ii) is owned in equity  interest,  in any degree,  by the first
Person,  or (iii) is owned, as to a majority of its equity interest,  by a third
Person who is an  Affiliate of the first  Person  under  provisions  (i) or (ii)
hereof.

                  "Agent"  means  Nationsbank  of  Tennessee,  N.A.,  a national
banking association, in its capacity as Agent for the Senior Lenders pursuant to
the Senior Loan Agreement.

                  "Blockage Notice" means a written notice given by Agent to 
Subordinated Lender






<PAGE>



stating that an Event of Default exists under the Senior Debt Agreements,  which
notice  shall  remain  in  effect  (i) in the case of an Event  of  Default  for
nonpayment  of principal or interest by Borrower or an Event of Default  arising
from the  filing  of a  proceeding  under an  Insolvency  Law,  from the date of
issuance of the  Blockage  Notice  until the earlier of the Full  Payment of the
Senior Debt or Agent's written notice to  Subordinated  Lender that the Event of
Default has been waived by or cured to the  satisfaction  of Agent,  (ii) in the
case of any other  Event of Default,  from the date of issuance of the  Blockage
Notice  until the earlier of (a) one hundred  seventy-nine  (179) days after the
issuance  thereof,  (b) Agent's written notice to  Subordinated  Lender that the
Event of Default  has been  waived by or cured to the  satisfaction  of Agent or
otherwise  ceased to exist,  or (c) the date of Full Payment of the Senior Debt;
provided,  however, that (x) no Blockage Notice under (ii) hereof may be imposed
more than twice in any rolling 360-day period and (y) there must be at least 180
consecutive  days in each  rolling  360-day  period in which no Blockage  Notice
under (ii) above is in effect.

                  "Bona Fide  Purchaser"  means a Person  that (i) is not liable
for  the  Senior  Debt  (either  generally  or by the  encumbrance  of  property
therefor),  (ii) is not an  Affiliate of any Person who is liable for the Senior
Debt (either  generally or by the encumbrance of property  therefor),  and (iii)
purchases all or any portion of the  Subordinated  Debt in  compliance  with the
provisions of this Agreement.  A wholly-owned  subsidiary of Subordinated Lender
(other than Borrower) shall be regarded as a Bona Fide Purchaser.

                  "Borrower" means Response Oncology, Inc., a Tennessee 
corporation, and its successors.

                  "Equity  Securities" means common or preferred stock issued by
Borrower,  which stock is not subject to any  obligation  of redemption or other
obligation  of Borrower or any  subsidiary  of Borrower to purchase or cause the
purchase of such stock.

                  "Full  Payment"  of the Senior  Debt means the  payment of all
principal  (in an amount not to exceed  ($35,000,000.00),  interest and expenses
arising under the Senior Debt Agreements.

                  "Insolvency  Law" means the United States  Bankruptcy Code and
any other  present  or future  federal  or state law  constituting  liquidation,
conservatorship,  moratorium,  receivership,  rearrangement,  reorganization  or
similar debtor relief laws.

                  "Payment" means any money, security interest or other value or
benefit  directly or indirectly  given by or on behalf of Borrower to or for the
benefit of Subordinated  Lender on account of the Subordinated Debt, or received
directly or indirectly by  Subordinated  Lender from any other source on account
of the Subordinated Debt, whether such money, etc. is characterized as a payment
to  reduce  the  Subordinated  Debt,  as  a  reserve  for  the  payment  of  the
Subordinated




                                       2


<PAGE>



Debt, as consideration for the purchase of the Subordinated Debt or any interest
therein, or otherwise, except that consideration received by Subordinated Lender
from a Bona Fide Purchaser shall not be considered a Payment.

               "Permitted Payments" means Payments that are paid in U.S. Dollars
and which meet either of the following additional criteria:

              (a)  Payments  that (i)  represent  only  interest  accrued on the
       Subordinated  Debt,  (ii) are paid by Borrower  directly to  Subordinated
       Lender no earlier than the scheduled due dates thereof as provided in the
       Subordinated  Note,  and  (iii) are made  when no  Blockage  Notice is in
       effect.

              (b)  Payments  made when an Event of Default has  occurred  and is
       continuing  under the Subordinated  Note after the applicable  Standstill
       Period  for such Event of  Default  has ended,  whether or not a Blockage
       Notice is then in  effect,  which  Payments  are  otherwise  made in full
       accordance  with the  provisions of this  Agreement  (including  turnover
       provisions).

              (c) Payments made by the issuance to Subordinated Lender of Equity
       Securities or warrants to purchase Equity Securities,  either pursuant to
       the Subordinated  Loan Agreement or in satisfaction of Subordinated  Debt
       pursuant to the conversion feature thereof or otherwise.

              (d)  Payments  made with the  proceeds  of an  issuance  of Equity
       Securities or Senior  Subordinated  Debt,  which payments are made within
       ten (10) days of Borrower's issuance thereof.

                  "Person" means any individual, corporation, partnership, joint
venture,  association,  joint stock company, trust, unincorporated organization,
government,  governmental agency or political  subdivision thereof, or any other
form of entity.

                  "Senior  Debt"  means all present  and future  obligations  of
Borrower to Senior  Lenders and Agent under the Credit  Facilities  described in
the Senior Loan Agreement, including, but not limited to, the obligations to pay
principal (in an amount not to exceed $35,000,000.00),  interest, expenses, fees
and other amounts arising under, and to perform all other obligations stated in,
the Senior Debt Agreements, and all refinancings thereof.

                  "Senior Debt  Agreements"  mean (i) the Senior Loan Agreement,
(ii) each  "Note,"  as  defined  in the Loan  Agreement,  (iii) all other  "Loan
Documents,"  as  defined  in the Loan  Agreement,  in  existence  as of the date
hereof,  (iv) any other  document  hereafter  arising that further  evidences or
secures the "Obligations" (as defined in the Loan Agreement); and (v) all







                                       3


<PAGE>



amendments, modifications, restatements, renewals, increases and extensions of 
any of the foregoing.

                  "Senior Lenders" means the "Lenders," as defined in the Senior
Loan Agreement from time to time.

                  "Senior Loan Agreement"  means that Loan Agreement dated as of
May 31, 1996, among Borrower,  Agent,  Union Planters  National Bank, a national
banking  association,  and  NationsBank of Tennessee,  N.A., a national  banking
association.

                  "Senior  Subordinated  Debt" means obligations of the Borrower
for principal,  interest,  expenses and any other amounts which are subordinated
in right of payment to the Senior  Debt to at least the extent  herein  provided
pursuant to a subordination agreement in form and substance acceptable to Agent,
but which are not either  Acquisition Debt or obligations  subordinated in right
of payment to the obligations of the Borrower evidenced by the Subordinated Note
and the Subordinated Loan Agreement.

                  "Standstill Period" means a period of time commencing upon the
date on which an Event of Default occurs under the Subordinated Note (as defined
therein) and ending upon the earlier of (i) one hundred  twenty (120) days after
the date on which  Subordinated  Lender  gives  written  notice  to Agent of the
occurrence  of the Event of Default  under the  Subordinated  Note other than an
Event of Default resulting from a proceeding under an Insolvency Law or an Event
of Default arising from an action described in (v) below),  (ii) sixty (60) days
after the  institution  of a  proceeding  by a party  other than  Agent  against
Borrower  under an Insolvency  Law, if such  proceeding  has not been  dismissed
within that time,  (iii) ten (10) days after the  institution of a proceeding by
Agent against  Borrower  under an  Insolvency  Law, (iv) ten (10) days after the
institution of a proceeding by Borrower under an Insolvency Law, or (v) ten (10)
days after  Agent's  filing of  judicial  debt  enforcement  proceedings  or its
exercise of other remedies against collateral for the Senior Debt.

                  "Subordinated  Debt" means the  obligations  of  Borrower  for
principal,   interest,   expenses  and  any  other  amounts  arising  under  the
Subordinated Note.

                  "Subordinated  Loan Agreement" means that Loan Agreement dated
as of October 4, 1996, between Borrower and Subordinated Lender.

                  "Subordinated  Lender" means Seafield Capital  Corporation,  a
Missouri corporation, its successors and its assigns.

                  "Subordinated  Note" means that  Adjustable  Rate  Convertible
Note made by Borrower dated October 4, 1996, in the original principal amount of
Twenty-Three Million Five






                                       4


<PAGE>



Hundred Thousand and No/100 Dollars  ($23,500,000),  a copy of which is attached
hereto as Exhibit A, and all  modifications,  extensions  and  renewals  thereof
entered into in accordance with the terms of this Agreement.

         2.   OWNERSHIP OF  SUBORDINATED  DEBT.  Subordinated Lender warrants to
Senior  Lenders and Agent that  Subordinated  Lender is the lawful  owner of the
Subordinated  Debt and the lawful holder of the  Subordinated  Note, free of any
security interest, lien, participation interest or other claim of any kind.

         3.   SUBORDINATION.  Subordinated Lender hereby agrees that the 
Subordinated Debt shall hereafter be subordinate to the Senior Debt with respect
to the rights of payment, security, collection and collection in bankruptcy, as 
and to the extent expressly set forth in this Agreement.

         4.   SUBORDINATION   OF  PAYMENTS.   Except  for  Permitted   Payments,
Subordinated  Lender shall not accept,  and Borrower shall not pay, any Payments
with  respect to the  Subordinated  Debt (of  principal,  interest,  expenses or
otherwise)  unless Agent gives its express prior written consent to Subordinated
Lender, which consent may be granted or withheld in Agent's discretion.

         5.   SUBORDINATION OF SECURITY.  The Subordinated Debt shall be 
unsecured.

         6.   SUBORDINATION OF RIGHT OF COLLECTION.  Notwithstanding the 
existence of an Event of  Default  under  the  Subordinated  Note  (as  defined
therein), acceleration thereunder or any other occurrence whatsoever,  
Subordinated Lender shall take no judicial  or other  action to collect the  
Subordinated Debt, to secure additional collateral therefor, to create a reserve
for its payment, or to seek relief under any Insolvency Law, and Borrower shall 
not voluntarily participate in any such collection action, provide additional  
collateral or create a reserve for the payment of the Subordinated Debt, without
the prior written approval of Agent, which consent may be granted or withheld in
Agent's discretion.  Any such action,  collateral or reserve purportedly 
established for the Subordinated Debt without Lender's  prior written  consent 
shall be void.  Notwithstanding  the foregoing,  following the occurrence of an 
Event of Default under the Subordinated  Note and the end of the Standstill 
Period for such Event of Default,  even though Full Payment of the Senior Debt 
may not have  occurred, and provided that the Event of Default has not been 
waived or cured, Subordinated Lender may seek enforcement of Borrower's  
obligations with respect to the Subordinated Debt through judicial debt 
collection proceedings or through the  commencement  of a proceeding  under an 
Insolvency Law, with all recoveries accomplished thereby to be paid to Agent for
application to the Senior Debt until the Full Payment of the Senior Debt, as and
to the extent provided in this Agreement.

         7.   SUBORDINATION OF COLLECTION IN BANKRUPTCY.  If Borrower becomes
a party to a voluntary or involuntary bankruptcy proceeding, reorganization 
proceeding or any 





                                       5


<PAGE>



other  action under an  Insolvency  Law,  following  any  applicable  Standstill
Period,  Subordinated Lender agrees to timely file a claim for the amount of the
Subordinated Debt, in form and substance approved by Agent (which approval Agent
shall  not  unreasonably  withhold).   Subordinated  Lender  hereby  irrevocably
authorizes  and  empowers  Agent  to file  claims  in the  Agent's  own name and
claiming through the Subordinated  Lender,  as may be necessary or advisable for
the enforcement of this Agreement in any proceeding  under an Insolvency Law and
to collect  and  receive  any and all  payments  or  distributions  which may be
payable or deliverable at any time upon or with respect to the Subordinated Debt
until Full Payment of the Senior Debt.  Agent will provide  Subordinated  Lender
with copies of any documents filed naming and claiming  through the Subordinated
Lender.  Subordinated Lender shall retain the right to vote and otherwise act in
any such proceeding,  including without limitation,  the right to file claims in
its own behalf,  and to vote to accept or reject any plan of partial or complete
liquidation, reorga nization, arrangement, composition, or extension.

         8. TURNOVER OF PAYMENTS.  Notwithstanding  any other  provision of this
Agreement,  any Payment made with respect to the Subordinated  Debt prior to the
Full  Payment of the Senior  Debt,  with the  exception  only of Payments  under
subsections (a), (c) and (d) of the above  definition of Permitted  Payments and
those  permitted by Agent's  consent  under  Section 4 hereof,  shall be held by
Subordinated  Lender in trust for  Agent,  shall not be  commingled  with  other
property of Subordinated  Lender, and shall immediately upon receipt be remitted
to Agent (or to the trustee or similar official if received in connection with a
proceeding  under an  Insolvency  Law) in kind  with any  necessary  endorsement
affixed for application to the Senior Debt, without the need of demand by Agent.

         9.  ACCELERATION  OF  SUBORDINATED  DEBT.  Prior  to  accelerating  the
Subordinated  Debt,  Subordinated  Lender shall give Agent written notice of any
Event of Default under the Subordinated  Debt (a notice  commencing a Standstill
Period  shall be regarded as a notice  under this  Section)  and allow Agent the
lesser of (i) the period of time equal to the applicable  Standstill  Period, or
(ii)  twenty  (20) days after  receipt of such  notice to cure or cause the cure
thereof,  unless the Event of  Default  arises  from the  filing of a  voluntary
proceeding by a Borrower under any  Insolvency  Law, in which case no obligation
of notice or right to cure shall apply.

         10. SUBORDINATION OF SUBORDINATED LENDER. Should any Payments made with
respect to the  Subordinated  Debt be applied to the Senior Debt pursuant to the
provisions of this Agreement, then, upon the Full Payment of the Senior Debt (as
determined  including such redirected  Payments),  Subordinated  Lender shall be
subrogated  to any  remaining  rights of Agent with  respect to the Senior Debt.
This  provision  does not create or evidence any obligation on the part of Agent
to exercise  diligence in  collection,  prevent the  impairment of collateral or
otherwise act in any respect for the benefit of  Subordinated  Lender in Agent's
dealings with Borrower or any collateral  securing the Senior Debt, it being the
essence of this






                                       6


<PAGE>



Agreement  that no such duties  exist on the part of Agent.  For purposes of the
subrogation  provided for in this Section 10, no payment or  distribution to any
Agent of any cash,  property or securities to which Subordinated Lender would be
entitled  except for the  provisions  of this  Agreement,  and no  payment  over
pursuant to the provisions of this Agreement to any Agent by Subordinated Lender
will,  as  among  the  Borrower,  its  creditors  (other  than  Agent)  and  the
Subordinated  Lender be deemed to be a payment or distribution by Borrower to or
on account of any Senior Debt. If other lenders are  similarly  subordinated  to
the Senior Debt at the time of its Full Payment, and if they are also subrogated
to the rights of Senior Lenders, all such subrogated  subordinated lenders shall
share in the rights of lender on a pari passu basis.

         11.       LEGEND.  The Subordinated Note shall bear a legend stating 
that it is subject to the provisions of this Agreement.

         12. TRANSFER. Subordinated Lender shall not negotiate, sell, assign, or
transfer the Subordinated  Note or any interest in the Subordinated Debt without
the prior written  approval of Lender,  except that prior  approval shall not be
necessary  if a  transfer  is (i) made to a Bona Fide  Purchaser,  and (ii) made
pursuant to documents that are expressly  subject to the terms and conditions of
this  Agreement  and  by  which  the  transferee  agrees  to  be  regarded  as a
Subordinated  Lender  hereunder,  which are  delivered to Lender within five (5)
days after they become  effective (such transfer to become  effective under this
Agreement only upon Agent's receipt  thereof).  No transfer of the  Subordinated
Debt shall release  Subordinated  Lender from  liability for any  obligations to
Agent or Lenders hereunder arising prior to the transfer thereof.

         13. UNCONDITIONAL  SUBORDINATION.  The enforceability of this Agreement
in  accordance  with its terms is not subject to any  condition and the validity
and  continuing  effect  hereof  shall not be impaired by any event  whatsoever,
including, but not limited to, the merger, consolidation,  cessation of business
or  liquidation  of Borrower;  the financial  decline or bankruptcy of Borrower;
Agent's  compromise  or  settlement  with or release of any party liable for the
Senior Debt;  Agent's  release of any  collateral  for the Senior Debt;  Agent's
failure to give Subordinated  Lender notice of any default,  Event of Default or
Unmatured Default by Borrower; the extension, amendment,  modification,  waiver,
increase  or renewal  of any of the Senior  Debt  Agreements  without  notice to
Subordinated  Lender;  or Agent's  failure to exercise  diligence in collection.
Subordinated  Lender agrees that this Agreement  shall be valid and binding upon
Subordinated Lender upon the delivery of this executed Agreement to Subordinated
Lender by or on behalf of Agent. Subordinated Lender and Agent shall each act in
good faith under this Agreement.

         14. MODIFICATION OF SUBORDINATED NOTE. Subordinated Lender and Borrower
agree that they shall give Agent written notice as promptly as is practicable of
any modification,  amendment or waiver of any provision of the Subordinated Note
and agree further that no such modification,  amendment or waiver shall be given
effect absent Agent's prior written  consent thereto if the effect thereof would
be to (i) modify covenants as to make them more




                                       7


<PAGE>



restrictive  on Borrower  including,  but not limited  to, the  modification  of
financial covenants against the interests of Borrower, (ii) create new Events of
Default or make existing Events of Default more  restrictive on Borrower,  (iii)
increase  the interest  rate  thereunder  or to create or increase  non-interest
payment  obligations of Borrower,  or (iv) provide for the payment of any amount
of  principal  or  interest  of the  Subordinated  Debt prior to its  originally
scheduled maturity.

         15.      EXPENSES.  In any effort to enforce this Agreement between 
Agent and Subordinated Lender, the prevailing party shall be entitled to recover
all court costs and reasonable attorney's fees and other expenses reasonably 
associated therewith.

         16.      TERMINATION.  Following the Full Payment of the Senior Debt,
this Agreement shall be terminated in writing by Agent.

         17.      NO MARSHALING OF ASSETS.  Agent may proceed against collateral
securing the Senior Debt and against parties liable therefor in such order as it
may  elect,  and  neither  Subordinated  Lender nor  Borrower  nor any surety or
guarantor for Borrower nor any other  creditor of Borrower  shall be entitled to
require  Agent to marshall  assets.  The benefit of any rule of law or equity to
the contrary is hereby expressly waived.

         18.      NOTICES.  Any communications concerning this Agreement or the 
credit described herein shall be addressed as follows:

                  As to Subordinated Lender:

                  Seafield Capital Corporation
                  Attn.:  P. Anthony Jacobs
                  2600 Grand Boulevard, Suite 500
                  Kansas City, MO 64108
                  Telecopier: (816) 842-2101

                  With a Copy To:

                  Lathrop Gates
                  Lathrop & Gage L. C.
                  2345 Grand Boulevard
                  Kansas City, MO 64108-2684
                  Telecopier: (816) 292-2001












                                       8


<PAGE>




                  As to Borrower:

                  Response Oncology, Inc.
                  Attn: Joseph Clark
                  1775 Moriah Woods Blvd.
                  Memphis, Tennessee 38117
                  Telecopier: (901) 683-7277

                  With a Copy To:

                  Baker, Donelson, Bearman & Caldwell
                  Attn: John A. Good, Esq.
                  165 Madison Ave., 20th Floor
                  Memphis, Tennessee 38103
                  Telecopier: (901) 577-2303

                  As to Agent:

                  NationsBank of Tennessee, N.A., Agent
                  Attn: David H. Dupuy
                  1 NationsBank Plaza
                  Nashville, TN 37239

                  With a Copy To:

                  Boult, Cummings, Conners & Berry
                  Attn: John E. Murdock III, Esq.
                  414 Union Street, Suite 1600
                  Nashville, Tennessee 37219
                  Telecopier: (615) 252-2380

Communications  shall only be  effective  when set forth in writing and actually
delivered to the addresses  stated  above.  Any party may change its address for
receipt of notices by submitting the change in writing to the other parties.

         19. PAYMENTS OTHERWISE PERMITTED.  Nothing contained in this Agreement,
the Senior Debt Agreements or the Subordinated  Note will prevent  Borrower,  at
any time,  from making  Payments at any time of  principal of or interest on, or
any other Payment in respect of, Subordinated Debt, except as expressly provided
in this Agreement.












                                       9


<PAGE>



         20.    PROVISIONS SOLELY TO DEFINE RELATIVE RIGHTS. The provisions of 
this Agreement are and are intended solely for the purpose of defining the 
relative rights of Agent, on the one hand, and Subordinated Lender, on the other
hand. Nothing contained in this Agreement, the Senior Debt Agreements,  the
Subordinated  Loan Agreement or the Subordinated Note is intended to or will (i)
impair,  as among the  Borrower,  its  creditors  (other  than the Agent and the
Senior Lenders) and Subordinated Lender, the obligations of the Borrower,  which
are absolute and unconditional,  to pay to Subordinated Lender the principal of,
or interest on, the  Subordinated  Debt,  or any other amount  payable by or any
other  security  issuable  by  Borrower  under  the  Subordinated  Note  or  the
Subordinated  Loan  Agreement,  as and when the same  becomes due and payable in
accordance with their terms; (ii) affect the relative rights against Borrower of
Subordinated  Lender and creditors of such Borrower other than the Agent and the
Senior  Lenders;  or (iii) prevent  Subordinated  Lender from  accelerating  any
amount  payable  pursuant  to the  Subordinated  Note and  exercising  all other
remedies otherwise permitted by applicable law upon default  thereunder,  except
as expressly provided in this Agreement.

         21.    AMENDMENT AND WAIVER IN WRITING.  No provision of this Agreement
can be amended or waived, except by a statement in writing signed by the party 
against which enforcement of the amendment or waiver is sought.

         22.    ENTIRE AGREEMENT. This Agreement represents the entire agreement
among the parties concerning the subordination of the Subordinated Debt.

         23.    SEVERABILITY.  Should any provision of this Agreement be invalid
or unenforceable for any reason, the remaining provisions hereof shall remain in
full effect.

         24.    APPLICABLE LAW.  The validity and construction of this Agreement
and all other documents executed with respect to the Senior Debt shall be 
determined according to the substantive laws of Tennessee, in which state this 
Agreement has been executed and delivered.

         25.    GENDER AND NUMBER. Words used herein indicating gender or number
shall be read as the context may require.

         26.    CAPTIONS NOT CONTROLLING.  Captions and headings have been 
included in this Agreement for the convenience of the parties, and shall not be 
construed as affecting the content of the respective paragraphs.

         27.    CONSENT TO JURISDICTION. Subordinated Lender, Agent and Borrower
hereby irrevocably consent to the jurisdiction of the United States District 
Court for the Middle District of Tennessee and of all Tennessee state courts 
sitting in Davidson County, Tennessee, for the purpose of any litigation to 
which Agent or Borrower may be a party and which concerns this Agreement or the 
Senior Debt.  It is further agreed that venue for any such action shall lie






                                       10


<PAGE>



exclusively  with courts  sitting in Davidson  County,  Tennessee,  unless Agent
agrees to the contrary in writing.  Matters between  Borrower and Agent shall be
determined by binding arbitration as provided in the Senior Debt Agreements.

         28.    JOINDER OF BORROWER;  PARTIES TO AMENDMENTS.  Borrower joins in 
the execution of this Agreement to acknowledge  and agree to the provisions  
hereof, but no rights in favor of Borrower  arise under this  Agreement  and  
provisions hereof may be  amended,  waived or restated  as between  Agent and  
Subordinated Lender without the joinder of Borrower.

         29.    CONSENT TO SENIOR DEBT.  Subordinated Lender hereby consents to
Borrower's incurring of the Senior Debt and waives any Event of Default that 
would arise under the Subordinated Note on account of Borrower's incurring the 
Senior Debt.







































                                       11


<PAGE>



         30. SIGNATURES BY FACSIMILE. This Agreement shall be effective upon the
parties'  exchange by telecopier of copies hereof  showing the signatures of the
other  parties;  provided,  however,  each party  shall  immediately  forward an
executed  original hereof to Agent. The failure of any party to so provide Agent
with an original  hereof  shall not impair the validity of this  Agreement,  but
shall entitle Agent to obtain specific  performance of the obligation to provide
an executed original of this Agreement.

                  Signature Page to Subordination Agreement

                  Executed the date first written above.

                                 THE   UNDERSIGNED    ACKNOWLEDGE   A
                                 THOROUGH  UNDERSTANDING OF THE TERMS
                                 OF THIS  AGREEMENT  AND  AGREE TO BE
                                 BOUND THEREBY:

                                 NATIONSBANK OF TENNESSEE, N.A., Agent


                                 By: _____________________________________
                                    


                                 Title: __________________________________
                                        


                                 RESPONSE ONCOLOGY, INC., Borrower

                                 By:  /s/   Joseph P. Clark
                                    --------------------------------
                                    
                                 Title:      President
 

                                 SEAFIELD CAPITAL CORPORATION,
                                 Subordinated Lender


                                 By: /s/   James R. Seward
                                    ---------------------------------  

                                 Title:  EVP  Chief Financial Officer









                                       12


<PAGE>






















































<PAGE>

                                                                    EXHIBIT 99.4



                               VOTING AGREEMENT



         This  Voting Agreement is made this ___ day of October,  1996,  between
Seafield  Capital   Corporation,   a  Missouri   corporation   ("Seafield")  and
_____________________________("Shareholder").

         WHEREAS,  the  Shareholder  is a  substantial  shareholder  of Response
Oncology,  Inc.,  a Tennessee  corporation  ("Response"),  owning  approximately
________ shares of Response Common Stock which  constitutes ____%  of all issued
and outstanding shares of Response Common Stock; and

         WHEREAS,  Response has requested  that Seafield loan to Response  $23.5
Million (the "Loan") on terms and conditions  set forth in the  Adjustable  Rate
Convertible Note (the "Note"), the Loan Agreement (the "Loan Agreement") and the
other loan documents, copies of which are attached hereto as Exhibit A; and

         WHEREAS, the Shareholder,  as a shareholder of Response,  has joined in
the request to Seafield for the Loan because receipt of the proceeds of the Loan
will  further the  interests  of Response  and  therefore  the  interests of the
Shareholder as a Response shareholder; and

         WHEREAS,  Seafield is willing to make the Loan to  Response  subject to
the provisions of the Note, the Loan Agreement and the other loan documents, all
attached as Exhibit A and the  undertaking  by the  Shareholder to vote and hold
shares of Response Common Stock as herein provided;

         WHEREAS,  the  Shareholder is willing to enter into and consummate this
Voting Agreement in order to induce Seafield to make the Loan;

         NOW, THEREFORE, in consideration of the premises and in order to induce
Seafield to make the Loan to Response,  the Shareholder  agrees with Seafield as
follows:

         1.   Definitions. Capitalized terms used in this Voting Agreement which
are not defined  herein  shall have the meanings ascribed to them in the Note or
the Loan Agreement.

         2.  Agreement  as  to  Voting.   In  the  event  Seafield   proposes  a
Recapitalization  Plan, the  Shareholder  agrees to vote or cause to be voted in
favor of the  Recapitalization  Plan all shares of Response  Common  Stock as to
which the Shareholder has directly or indirectly  (including  without limitation
through entities or  relationships  which are controlled by the Shareholder) the
right or power to vote.







                                       

<PAGE>



         3. Representations. The Shareholder represents and warrants to Seafield
that he owns of record _____________ shares of Response Common Stock and has the
right  directly or  indirectly  to vote or cause the voting of not fewer than an
additional ___________ shares of Response Common Stock.

         4. Restriction on Transfer. The Shareholder agrees not to sell, convey,
transfer,  or otherwise  dispose of any shares of Response  Common Stock, or any
interest  therein,  which are owned of record or beneficially by the Shareholder
on the date hereof or are  hereafter  acquired,  and the  Shareholder  agrees to
cause all shares of Response Common Stock, and all interests therein,  which are
owned of record or  beneficially by other persons or entities on the date hereof
or are hereafter  acquired by them, but as to which the Shareholder has directly
or indirectly  (including  without  limitation through entities or relationships
which are controlled by the Shareholder) the power to control the disposition or
investment, not to be sold, conveyed, transferred or otherwise disposed of.

         5.  Termination.  This Voting  Agreement and all rights and obligations
hereunder  shall  terminate  and be null and void from and after the earliest of
(a) payment in full of all  prinicipal of and interest on the Note, (b) the date
upon which the Recapitalization Plan is consummated, and (c) December 31, 1997.

         6. Miscellaneous. This Voting Agreement shall be a contract made under,
governed by and construed in accordance  with the internal laws (without  giving
effect to the conflict of law rules,  of the State of Tennessee).  Any provision
of  this  Voting   Agreement  which  is  prohibited  or   unenforceable  in  any
jurisdiction  shall,  as to such  jurisdiction,  be ineffective to the extent of
such  prohibition  or  unenforceability   without   invalidating  the  remaining
provisions hereof or thereof or affecting the validity or enforceability of such
provision in any other  jurisdiction,  it being the intent of the parties hereto
that the  remaining  provisions  hereof or thereof  shall be construed in such a
manner as to give  maximum  meaning  and  effect  thereto  as if the  invalid or
unenforceable  provision were not a part of this Voting  Agreement.  This Voting
Agreement shall be binding upon the parties hereto and their  respective  heirs,
personal representatives,  successors and assigns and shall inure to the benefit
of such parties and their respective heirs, personal representatives, successors
and assigns.  This Voting Agreement may be executed in multiple counterparts and
by the  parties  hereto  on  separate,  identical  counterparts;  each  shall be
considered an original,  but all of which shall constitute one single agreement.
Seafield  shall have the right to assign and  transfer any and all of its rights
and privileges  pursuant to this Voting  Agreement,  which  assignment may be in
whole or in part and at any time and from time to time.












                                       2


<PAGE>



         IN WITNESS WHEREOF,  the parties hereto have duly executed or caused to
be executed this Voting Agreement as of the date first above written.



                                       SHAREHOLDER


                                       __________________________________
                                                      (Name)
                                       __________________________________


                                       SEAFIELD CAPITAL CORPORATION


                                       By: ______________________________
                                           
                                       Name: ____________________________

                                       Title: ___________________________
































                                       3


<PAGE>






















































<PAGE>

                                                                    EXHIBIT 99.5


                                   Exhibit B

   THIS  WARRANT AND THE SHARES OF COMMON  STOCK  ISSUABLE  UPON  EXERCISE
   HEREOF HAVE NOT BEEN  REGISTERED  UNDER THE  SECURITIES ACT OF 1933, AS
   AMENDED,  OR ANY  APPLICABLE  STATE  SECURITIES  LAWS  AND  MAY  NOT BE
   TRANSFERRED  UNTIL (1) A REGISTRATION  STATEMENT  UNDER SUCH SECURITIES
   LAWS SHALL HAVE BECOME  EFFECTIVE  WITH REGARD  THERETO,  OR (2) IN THE
   OPINION OF COUNSEL  ACCEPTABLE TO THE COMPANY  REGISTRATION  UNDER SUCH
   SECURITIES  LAWS IS NOT  REQUIRED  IN  CONNECTION  WITH  SUCH  PROPOSED
   TRANSFER.

                             RESPONSE ONCOLOGY, INC.

                        Warrant to Purchase Common Stock
                        --------------------------------


         Response  Oncology,  Inc.,  a Tennessee  corporation  (the  "Company"),
hereby  certifies  that Seafield  Capital  Corporation,  a Missouri  corporation
("Seafield")  is entitled,  subject to the terms and conditions set forth below,
to purchase from the Company upon surrender of this Warrant 1,000,000 fully paid
and non-assessable  shares of the Common Stock, par value $.01 per Share, of the
Company (the  "Shares"),  at an exercise  price per share equal to the lesser of
(i) the average of the closing  prices of the Common  Stock on the NASDAQ  Stock
Market's  National Market for the five (5)  consecutive  trading days ending one
(1)  trading day prior to the date on which the Warrant  Issuance  Event  occurs
(for purposes of computing  such average,  such closing  trading prices shall be
appropriately adjusted to eliminate the impact of any dividend, whether in cash,
securities or other property, stock split,  reclassification,  recapitalization,
reverse  split or similar  event,  announced  or  occurring  with respect to the
Company's Common Stock during such five (5) trading day period) and (ii) $11.00.

         This  Warrant  shall be  exercisable  for the  three  (3)  year  period
commencing  on [date of  Warrant  Issuance  Event]  and  ending  at the close of
business on [3rd  Anniversary of Warrant  Issuance  Date],  and no rights herein
given to the holder of this Warrant shall exist thereafter.

         As used herein, the term "Company" includes any corporation which shall
succeed to or assume the  obligations  of the  Company  hereunder,  and the term
"Shares" which may be purchased upon exercise of this Warrant  includes stock of
any class or classes (however  designated) of the Company,  the holders of which
shall have the right  (without  limitation  as to amount)  either to all or to a
portion of the balance of current dividends and liquidating  distributions after
the  payment of  dividends  and  distributions  on any  securities  entitled  to
preference.








  

<PAGE>



         The number and  character  of the Shares  which may be  purchased  upon
exercise  of this  Warrant  and the  exercise  price per Share  are  subject  to
adjustment from time to time as hereinafter provided.

1.       Compliance with the Securities Act of 1933.
         ------------------------------------------

         (a) The  holder  of this  Warrant  agrees  that the  Company,  if it so
desires,  may permit  transfers  of this Warrant and all Shares  purchased  upon
exercise  hereof  only  when the  securities  which the  holder of this  Warrant
desires to transfer have been  registered  under the  Securities Act of 1933, as
amended (the "Securities Act"), and any applicable state or other jurisdiction's
securities  laws, or when the request for transfer is  accompanied by an opinion
of counsel  (which  opinion  and the counsel  rendering  such  opinion  shall be
reasonably  acceptable  to the  Company) to the effect that the sale or proposed
transfer does not require  registration under the Securities Act or any state or
other jurisdiction's  securities laws. The holder of this Warrant further agrees
that the  following  legend,  if the  Company so  desires,  may be placed on the
certificate  or  certificates  representing  any of the  Shares  purchased  upon
exercise of this  Warrant and a stop  transfer  order may be placed with respect
thereto:

    THE SHARES OF COMMON STOCK  REPRESENTED  BY THIS  CERTIFICATE  HAVE NOT
    BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933, AS AMENDED,  OR ANY
    APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE TRANSFERRED UNTIL (1) A
    REGISTRATION  STATEMENT UNDER SUCH SECURITIES ACT AND APPLICABLE  STATE
    SECURITIES LAWS SHALL HAVE BECOME EFFECTIVE WITH REGARD THERETO, OR (2)
    IN THE OPINION OF COUNSEL ACCEPTABLE TO THE COMPANY, REGISTRATION UNDER
    SUCH  SECURITIES ACT AND SUCH APPLICABLE  STATE  SECURITIES LAWS IS NOT
    REQUIRED IN CONNECTION WITH SUCH PROPOSED TRANSFER.

The holder of this warrant understands that the Company shall have no obligation
to permit the  transfer  of this  Warrant to any person if such  transfer  would
constitute  a  violation  of any  applicable  federal or state  securities  law,
including the Securities Act.

         (b) In the event of a transfer of this Warrant in  accordance  with the
provisions  of this Section 1 and upon  surrender of this Warrant to the Company
or its transfer agent's principal office for such purpose,  the Company,  at its
expense,  will issue and deliver a new Warrant of like tenor in the name of such
holder or holders (upon payment of any applicable  transfer taxes) as the holder
hereof  may  direct.  Until  this  Warrant  is  transferred  on the books of the
Company,  the Company may treat the  registered  holder hereof as absolute owner
for all purposes, without being affected by any notice to the contrary.









                                       2


<PAGE>



         (c) The  holder  of this  Warrant  agrees  that upon  exercise  of this
Warrant,  the holder shall deliver  written  investment  representations  to the
Company in form  reasonably  satisfactory  to the  Company  and shall  otherwise
reasonably  comply with any current  requirements of the Securities and Exchange
Commission and any applicable  state  securities  laws as may be required in the
reasonable  opinion of counsel  for the  Company at the time of the  exercise of
this  Warrant to allow the  issuance  of the shares to the holder in  compliance
with such laws.

2.       Adjustments of Number of Shares Issuable Upon Exercise of Warrants.
         ------------------------------------------------------------------

         (a) In the  event of any  change  in the  outstanding  Shares of Common
Stock of the  Company by reason of a stock  dividend,  split or  combination  in
which the Company is the surviving corporation or other similar change affecting
the capital  structure of the Company,  the number of Shares  issuable  upon the
exercise of this Warrant and the exercise price per Share shall be appropriately
adjusted by the Company to reflect such change.

         (b) In  case  of any  capital  reorganization  or  reclassification  of
Shares,  or in case of any  consolidation  or merger of the Company with or into
any other  corporation,  or in case of any sale to  another  corporation  of the
properties and assets of the Company as or substantially  as an entirety,  then,
and in each such  case,  the  holder  of this  Warrant  shall  have the right to
receive  upon the exercise  hereof as provided in Section 7 hereof,  at any time
after the consummation of such reorganization, reclassification,  consolidation,
merger or sale,  the kind and amount of shares of stock or other  securities  or
property receivable upon such reorganization,  reclassification,  consolidation,
merger or sale by a holder of the number of Shares  issuable  upon  exercise  of
this  warrant  immediately  prior  to  such  reorganization,   reclassification,
consolidation,  merger  or  sale;  and in  any  such  case,  if  necessary,  the
provisions set forth herein with respect to the rights and interests  thereafter
of the  holder  of this  Warrant  shall be  appropriately  adjusted  so as to be
applicable,  as nearly  as may  reasonably  be, to any  shares of stock or other
securities or property thereafter  receivable upon the exercise of this Warrant.
The  above  provisions  of  this  subparagraph  (b)  shall  similarly  apply  to
successive   reclassifications   and   changes  of  Shares  and  to   successive
consolidations, mergers, sales or conveyances.

         (c)  Anything in this  Section 2 to the  contrary  notwithstanding,  no
adjustment  in the number of Shares  shall be required  unless  such  adjustment
would  require an increase or decrease of at least 1% in such number;  provided,
however, that any adjustments which by reason of this Section 2 are not required
to be made shall be carried  forward and taken into account  (together  with any
other  adjustments  so  carried  forward)  in  any  subsequent  adjustment.  All
calculations under this Section 2 shall be made to the nearest  one-hundredth of
a Share,  as the case may be, but in no event shall the Company be  obligated to
issue fractional Shares upon the exercise of this Warrant.





                                       3


<PAGE>



         (d)  Immediately  upon any  adjustment  pursuant to this Section 2, the
Company  shall send  written  notice  thereof to the holder of this  Warrant (as
provided in Section 9 hereof), which notice shall state the increase or decrease
in the number of Shares to be acquired upon exercise of this Warrant, and in the
exercise  price per  Share,  setting  forth in  reasonable  detail the method of
calculation and the facts upon which such calculation is based.

3.       Notice of Reclassifications, Consolidations, Mergers, etc.
         ---------------------------------------------------------

         In  case  of any  capital  reorganization  or  reclassification  of the
capital  stock of the Company or a  consolidation  or merger of the Company with
another corporation,  or the full dissolution,  liquidation or winding up of the
Company,  or a sale of all or substantially all its assets (whether voluntary or
involuntary),  then in any one or more of said cases, the Company shall mail (as
provided  in  Section 9 hereof) a notice to the  holder of this  Warrant  at the
address of said holder on the records of the Company,  at least 10 days prior to
the  date  such   reorganization,   reclassification,   consolidation,   merger,
dissolution, liquidation, winding up or sale shall take place. Such notice shall
also  specify the date as of which  shareholders  of record shall be entitled to
exchange  their  Shares  for  other  securities  or  property  pursuant  to such
reorganization,  reclassification,  consolidation or merger, or to receive their
respective  distributive  Shares in the event of such dissolution,  liquidation,
winding  up or sale,  as the case may be.  Such  notice  shall  also set forth a
statement  of the effect of such  action (to the extent  then known) on the kind
and amount of shares of capital stock and property  receivable  upon exercise of
this Warrant.

4.       Covenants of the Company.
         ------------------------

         The Company  covenants  and agrees that all Shares  which may be issued
upon the exercise of this Warrant  shall,  upon  issuance,  be duly  authorized,
validly  issued,  fully  paid and  non-assessable  and free from all  preemptive
rights of any shareholder  and all taxes,  liens and charges with respect to the
issue  thereof   (other  than  taxes  in  respect  of  any  transfer   occurring
contemporaneously with such issue).

5.       Warrant Holder Not Deemed a Shareholder.
         ---------------------------------------

         No  holder  of this  Warrant,  as such,  shall be  entitled  to vote or
receive  dividends or be deemed the holder of Shares for any purpose,  nor shall
anything  contained  in this  Warrant  be  construed  to confer  upon the holder
hereof,  as such, any of the rights of a shareholder of the company or any right
to vote,  give or withhold  consent to any corporate  action,  receive notice of
meetings,  receive dividends, or subscription rights, or otherwise, prior to the
issuance of record to the holder of this  Warrant of the Shares which he is then
entitled to receive upon the due exercise of this Warrant.




                                       4


<PAGE>



6.       No Limitation on Corporate Action.
         ---------------------------------

         No  provisions  of this  Warrant  and no right  or  option  granted  or
conferred  hereunder  shall in any way limit,  affect or abridge the exercise by
the Company of any of its corporate rights or powers to recapitalize,  amend its
Charter,  reorganize,  consolidate or merge with or into another corporation, or
to transfer  all or any part of its  property or assets,  or the exercise of any
other of its corporate rights and powers.

7.       Exercise of Warrant.
         -------------------

         (a) This  Warrant may be  exercised  in whole or in multiples of 25,000
shares.  The holder of this Warrant may exercise the same by  surrendering  this
Warrant,  with the form of  subscription at the end hereof duly executed by such
holder,  to the Company at the principal office of the Company,  until such time
as the Company  may appoint a transfer  agent and  thereafter  at the  principal
office of the transfer agent,  accompanied by payment in cash or by certified or
official bank check, payable to the order of the Company, of the sum obtained by
multiplying  the  number  of  Shares  being  purchased  (giving  effect  to  any
adjustments  therein)  by the  exercise  price per  Share,  plus any  applicable
transfer tax. If the Company  appoints a transfer  agent,  the Company agrees to
notify the  holder of this  Warrant of the  address  of such  agent's  principal
office.

         (b) As soon as  practicable  after exercise of this Warrant and payment
of the  sum  payable  upon  such  exercise,  and in any  event  within  20  days
thereafter,  the Company will cause to be issued in the name of and delivered to
the holder hereof,  or as such holder may direct (upon payment by such holder of
any applicable  transfer taxes), a certificate or certificates for the number of
fully paid and  non-assessable  Shares or other  securities or property to which
such  holder  shall  be  entitled  upon  such  exercise,  plus,  in  lieu of any
fractional  Shares to which such holder would otherwise be entitled,  cash equal
to such  fraction  multiplied  by the then current fair market value of one full
Share.  Issuance and delivery of the Shares  deliverable  on the due exercise of
this Warrant may be  postponed by the Company and its transfer  agent during any
period,  not exceeding 40 days,  for which the transfer books of the Company for
its Common  Stock are  closed  between  (1) the record  date set by the Board of
Directors  for  the  determination  of  shareholders  entitled  to vote at or to
receive notice of any shareholders'  meeting,  or entitled to receive payment of
any dividends or to any allotment of rights or to exercise  rights in respect of
any change,  conversion or exchange of capital  stock,  and (2) the date of such
allotment of rights,  or the date when any such change or conversion or exchange
of capital stock shall go into effect, as the case may be.

         (c) If this Warrant is exercised  in part as permitted  hereunder,  the
Company,  at its  expense,  will issue and  deliver a new  Warrant of like tenor
(giving effect to all prior exercises) in the name of the holder.




                                       5


<PAGE>



8.       Registration Rights.
         -------------------

         The original  holder of this Warrant and its permitted  successors  and
assigns are  entitled to the  registration  rights  granted with respect to this
Warrant and the Shares issued upon  exercise of this Warrant in accordance  with
that certain Loan  Agreement,  dated as of October 4, 1996,  between the Company
and Seafield.

9.       Notices.
         -------
    
         All  communications  hereunder  shall be in writing and, if sent to the
Company,  shall be  mailed by  registered  or  certified  mail or  delivered  or
telegraphed  and  confirmed  in writing to 1775  Moriah  Woods  Blvd.,  Memphis,
Tennessee  38117;  Attention:  Joseph P.  Clark,  President,  and if sent to the
holder  hereof,  shall be mailed by registered or certified mail or delivered or
telegraphed  and confirmed in writing to the address of such holder as set forth
in the Company's records.  The Company or any such holder may change its address
by proper notice to all holders or the Company, as the case may be.


Dated: _______________, 199__

                                             RESPONSE ONCOLOGY INC.




Attest: ________________________             By: ______________________________
     






















                                       6


<PAGE>



                                   ASSIGNMENT

         FOR VALUE RECEIVED __________________________ hereby sells, assigns and
transfers unto ____________________________  the within Warrant, and does hereby
irrevocably constitute and appoint _________________________,  Attorney-in-Fact,
to transfer the said Warrant on the books of the  within-named corporation with
full power of substitution.

Dated: _____________________, 199__
      


Person to Receive New Warrant:



_______________________________
              Name




_______________________________
             Address




_______________________________




_______________________________
    Tax Identification Number



                                             _________________________________
                                                        Signature




                                             _________________________________
                                                        Signature

NOTICE:  The signature(s) to this Assignment must correspond with the name(s) as
         written upon the face of the Certificate, in every particular, without
         alteration or enlargement or any change whatever.



                                       7


<PAGE>


                               SUBSCRIPTION FORM

                      TO BE EXECUTED BY THE REGISTERED HOLDER
                            TO EXERCISE THIS WARRANT

                             RESPONSE ONCOLOGY, INC.

         The  undersigned  hereby  exercises  the right to purchase ____________
Shares of Common Stock or other  securities or property covered by this Warrant.
The undersigned  hereby  exercises such right to purchase in accordance with the
conditions  of the Warrant and  herewith  makes  payment in full of the Purchase
Price of such Shares of Common Stock or other securities or property.


Dated: _______________________, 199__
 


                                          _________________________________
                                                      Signature



                                          _________________________________
                                                      Signature


 
                                          _________________________________
                                                       Address



                                          _________________________________
                                          Number of Shares of Common Stock Being
                                          Purchased or Description of other 
                                          Securities or Property



                                          $________________________________
                                                     Purchase Price


NOTICE:      The signatures to this Subscription Form must correspond with
             the name(s) as written  upon the face of the  Certificate,  in
             every  particular,  without  alteration or  enlargement or any
             change whatever.






                                       8


<PAGE>





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