RESPONSE ONCOLOGY INC
8-K, 1996-04-30
SPECIALTY OUTPATIENT FACILITIES, NEC
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<PAGE>   1




                                 UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                           WASHINGTON, D.C. 20549





                                  FORM 8-K



                           CURRENT REPORT PURSUANT
                        TO SECTION 13 OR 15(d) OF THE
                       SECURITIES EXCHANGE ACT OF 1934





      Date of report (Date of earliest event reported): APRIL 15, 1996



                           RESPONSE ONCOLOGY, INC.
           (Exact name of registrant as specified in its charter)

                                  TENNESSEE
               (State or other jurisdiction of incorporation)


            0-15416                                 62-1212264
    (Commission File Number)            (I.R.S. Employer Identification No.)


              1775 MORIAH WOODS BLVD., MEMPHIS, TENNESSEE 38117
         (Address of principal executive offices, including Zip Code)


                                (901) 761-7000
             (Registrant's telephone number, including Area Code)


                                NOT APPLICABLE
        (Former name or former address, if changed since last report)


<PAGE>   2

ITEM 2. ACQUISITION OR DISPOSITION OF ASSETS.

        On April 15, 1996, the Registrant and a wholly owned subsidiary of the
Registrant acquired (the "Transaction") from unaffiliated individual sellers
(the "Sellers") 100% of the outstanding general partnership interests (the
"Acquired Interests") of Knoxville Hematology Oncology Associates, a Tennessee
general partnership (the "Acquired Business"). The total consideration (the
"Purchase Price") for the Acquired Interests was $9 million, approximately
$8,190,000 of which was paid in cash, approximately $150,000 was paid in the
form of the Registrant's unsecured interest-bearing promissory note due April
12, 1997 (the "Note") and the balance being paid through assumption of
approximately $660,000 of accounts payable and capital leases.  The Note may,
at the election of the holder, be paid in shares of common stock of the
Registrant (the "Registrant Common Stock") based on a conversion price of
$11.75 per share of the Registrant's common stock.  In addition, 80,000 stock
purchase warrants (the "Warrants") exercisable at $11.75 were issued as
additional purchase price.  The delivery of the Note, the Warrants and the
Registrant Common Stock potentially issuable by the Registrant in full or
partial satisfaction of the Note or upon exercise of the Warrants have not been
registered under the Securities Act of 1933 in reliance upon an exemption from
such registration.

        The Acquired Interests were purchased by the Registrant directly from
the Sellers, who constituted all of the partners of the Acquired Business.  At
the time of the Transaction, no Seller had a material relationship with the
Registrant.  Upon consummation of the Transaction, 99% of the interests in the
profits, losses and capital of the Acquired Business were owned by the
Registrant, with the remaining 1% being owned by a wholly owned subsidiary of
the Registrant.  The assets of the Acquired Business include medical equipment,
accounts receivable, office furnishings and fixtures, rights under a certain
lease for certain office space, employee base and expertise, know-how in respect
of management of a medical practice in the oncology and hematology specialty,
computer systems, accounting books and records and other intangible assets. 
Such assets were historically used in the conduct by the Acquired Business of a
group medical practice in the oncology and hematology specialty.

        Simultaneous with the consummation of the Transaction, a newly-formed
professional limited liability company wholly owned by the Sellers and formed
to continue the group medical practice theretofore conducted by the Sellers
(the "New PLLC") entered into a long-term management services agreement (the
"Service Agreement") with the Registrant providing for the management by the
Registrant of the non-medical aspects of the practice thereafter conducted by
the New PLLC.  Pursuant to the Service Agreement, the Registrant will manage
the non-medical aspects fo the New PLLC's business and will permit the New PLLC
to use office space, equipment and other assets owned or leased by the
Registrant in exchange for an agreed-upon management fee.

        The cash portion of the Purchase Price was provided from the proceeds of
a $10 million loan from Seafield Capital Corporation to be used to finance
acquisitions.  The loan has a maturity date of December 31, 1996, bears interest
at the rate of prime plus 1%, is unsecured and, after August 1, 1996, is
convertible at the option of Seafield into shares of Response common stock at a
conversion price equal to the market price of the common stock at the time of
conversion.

ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

        It is impracticable for the Registrant to provide with this Current
Report the financial statements for the Acquired Business required to be filed
pursuant to Rule 3-05 of Regulation S-X and pro forma financial information
required to be filed pursuant to Article 11 of Regulation S-X because all such
financial statements and information are presently not available.  Such
financial statements and pro forma financial information shall be filed as soon
as they become available, but in any event no later than June 29, 1996.

        In addition to the foregoing, the following exhibits are filed as a part
of this report:

1.      Purchase and Sale Agreement by and among Response Oncology, Inc., 
Knoxville Hematology Oncology Associates and Partners of Knoxville Hematology
Oncology Associates dated April 12, 1995.

<PAGE>   3

2.      Service Agreement between Response Oncology, Inc. and Knoxville 
Hematology Oncology Associates, P.L.L.C. dated April 12, 1996.

                                  SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

<TABLE>
<S>                                         <C>
                                            RESPONSE ONCOLOGY, INC.  


Dated:  April 30, 1996                      By: /s/ John A. Good
                                               --------------------------------------------------------
                                               John A. Good, Executive Vice President & General Counsel

</TABLE>

<PAGE>   4


                                 EXHIBIT INDEX

<TABLE>
<CAPTION>
                                                                                            SEQUENTIALLY
EXHIBIT                                                                                       NUMBERED
NUMBER                                   DESCRIPTION OF EXHIBIT                                 PAGE
- -------                                  ----------------------                                 ----
<S>               <C>
10(q)             Purchase and Sale Agreement by and among Response Oncology, Inc.,
                  Knoxville Hematology Oncology Associates and Partners of Knoxville
                  Hematology Oncology Associates dated April 12, 1996


10(r)             Service Agreement between Response Oncology, Inc., Knoxville Hematology
                  Oncology Associates, P.L.L.C. and Members of Knoxville Hematology
                  Oncology Associates, P.L.L.C. dated April 12, 1996*
</TABLE>


*  PORTIONS OF EXHIBIT 10(r) HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE 
COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT.



<PAGE>   1
                                                                  EXHIBIT 10(q)





                          PURCHASE AND SALE AGREEMENT

                                  BY AND AMONG

                            RESPONSE ONCOLOGY, INC.,

                    KNOXVILLE HEMATOLOGY ONCOLOGY ASSOCIATES

                                      AND

              PARTNERS OF KNOXVILLE HEMATOLOGY ONCOLOGY ASSOCIATES

                                 APRIL 12, 1996





<PAGE>   2



                          PURCHASE AND SALE AGREEMENT

         THIS PURCHASE AND SALE AGREEMENT, dated as of April 12, 1996, by and
among RESPONSE ONCOLOGY, INC, a Tennessee corporation (the "Purchaser"), and
the HOLDERS OF ALL GENERAL PARTNERSHIP INTERESTS OF KNOXVILLE HEMATOLOGY
ONCOLOGY ASSOCIATES, a Tennessee general partnership (the "Partnership"), each
of whom, together with his or her state of residence and address is listed on
Exhibit A hereto (collectively, the "Partners" and, individually, a "Partner").

                              W I T N E S S E T H:

         WHEREAS, the Partners own 100% of the interests as general partners
(the "Partnership Interests") in the Partnership which is engaged in the
practice of medicine in the specialty of general oncology and hematology; and

         WHEREAS, each of the Partners desires to sell and the Purchaser
desires to purchase 100% of the Partnership Interests of the Partnership from
the Partners on the terms and subject to the conditions set forth herein;

         NOW, THEREFORE, in consideration of the mutual covenants,
representations, warranties and promises herein contained, and for other good
and valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the parties hereto agree as follows:


         1.      DEFINITIONS. The following terms, as used herein, have the
                 following meanings:

         "Adverse Consequences" means all actions, suits, proceedings,
hearings, investigations, charges, complaints, claims, demands, injunctions,
judgments, orders, decrees, rulings, damages, dues, penalties, fines, costs,
amounts paid in settlement, Liabilities, obligations, Taxes, liens, losses,
expenses, and fees, including court costs and attorneys' fees and expenses.

         "Affiliate" has the meaning set forth in Rule 12-2 of the regulations
promulgated under the Securities Exchange Act.

         "Applicable Rate" means the corporate base rate of interest announced
from time to time by First Tennessee Bank National Association, Memphis,
Tennessee plus two percent (2%).

         "Assumed Liabilities" has the meaning set forth in Section 2(a)(ii)
below.

         "Basis" means any past or present fact, situation, circumstance,
status, condition, activity, practice, plan, occurrence, event, incident,
action, failure to act, or transaction that forms or could form the basis for
any specified consequence.

         "Closing" has the meaning set forth in Section 2(c) below.

         "Closing Date" has the meaning set forth in Section 2(c) below.

         "Code" means the Internal Revenue Code of 1986, as amended.

         "Employee Benefit Plan" means any (a) nonqualified deferred
compensation or retirement plan or arrangement which is an Employee Pension
Benefit Plan, (b) qualified defined contribution retirement plan or arrangement
which is an Employee Pension Benefit Plan, (c) qualified defined benefit
retirement plan or





<PAGE>   3


arrangement which is an Employee Pension Benefit Plan (including any
Multi-employer Plan), or (d) Employee Welfare Benefit Plan or material fringe
benefit plan or program.

         "Employee Pension Benefit Plan" has the meaning set forth in ERISA
Section 3(2).

         "Employee Welfare Benefit Plan" has the meaning set forth in ERISA
Section 3(1).

         "Environmental, Health, and Safety Laws" means the Comprehensive
Environmental Response, Compensation and Liability Act of 1980, the Resource
Conservation and Recovery Act of 1976, the Occupational Safety and Health Act
of 1970, the Medical Waste Tracking Act of 1988, the U. S. Public Vessel
Medical Waste Anti-Dumping Act of 1988, the Marine Protection, Research and
Sanctuaries Act and Human Services, National Institute for Occupational Safety
and Health, Infections Waste Disposal Guidelines, Publication No. 88-119, each
as amended, together with all other laws (including rules, regulations, codes,
plans, injunctions, judgments, orders, decrees, rulings, and charges
thereunder) of federal, state, local, and foreign governments (and all agencies
thereof) concerning pollution or protection of the environment, public health
and safety, or employee health and safety, including laws relating to
emissions, discharges, releases, or threatened releases of medical wastes,
pollutants, contaminants, or chemical, industrial, hazardous, or toxic
materials or wastes into ambient air, surface water, ground water, or lands or
otherwise relating to the manufacture, processing, distribution, use,
treatment, storage, disposal, transport, or handling of pollutants,
contaminants, or chemical, industrial, hazardous, or toxic materials or wastes.

         "ERISA" means the Employee Retirement Income Security Act of 1974, as
amended.

         "Extremely Hazardous Substance" has the meaning set forth in Section
302 of the Emergency Planning and Community Right-to-Know Act of 1986, as
amended.

         "Fiduciary" has the meaning set forth in ERISA Sec. 3(21).

         "Financial Statement" has the meaning set forth in Section 4(c) below.

         "GAAP" means United States generally accepted accounting principles as
in effect from time to time.

         "Intangible Assets" means all intangible assets of the Partnership
that are not Medical Practice Assets, including, without limitation, the
Seller's base of non-medical employees, management information systems,
business know-how as it relates to operation of the business aspects of an
oncology practice, accounting books and records and non-medical goodwill.

         "Intellectual Property" means (a) all inventions (whether patentable
or unpatentable and whether or not reduced to practice), all improvements
thereto, and all patents, patent applications, and patent disclosures, together
with all reissuances, continuations, continuations-in-part, revisions,
extensions, and reexaminations thereof, (b) all trademarks, service marks,
trade dress, logos, trade names, and corporate names, together with all
translations, adaptations, derivations, and combinations thereof and including
all goodwill associated therewith, and all applications, registrations, and
renewals in connection therewith, (C) all copyrightable works, all copyrights,
and all applications, registrations, and renewals in connection therewith, (d)
all mask works and all applications, registrations, and renewals in connection
therewith, (e) all trade secrets and confidential business information
(including ideas, research and development, know-how, formulas, compositions,
manufacturing and production processes and techniques, technical data, designs,
drawings, specifications, customer and supplier lists, pricing and cost
information, and business and marketing plans and proposals), (f) all computer
software (including data and related documentation), (g) all other proprietary
rights, and (h) all copies and tangible embodiments thereof (in whatever form
or medium).





<PAGE>   4




         "Inventory" means the inventory of pharmaceuticals and medical
supplies owned by the Partnership as of the close of business on the day prior
to the Closing Date.

         "Investments" means investment assets of the Partnership including
stocks, bonds, certificates of deposits, interests in non-medical partnerships,
joint ventures, corporations, limited liability companies and other entities.

         "Knowledge" means actual knowledge after reasonable investigation.

         "Liability" means any liability (whether known or unknown, asserted or
unasserted, absolute or contingent, accrued or unaccrued, liquidated or
unliquidated, and whether due or to become due), including any liability for
Taxes.

         "Medical Practice Assets" means all assets and property owned by the
Partnership and used in its medical practice which cannot lawfully be acquired
and owned by the Purchaser, including, without limitation, all patient charts
and patient records that do not constitute business records, licenses to
practice medicine and goodwill related to Seller's patient base and/or medical
practice.

         "Most Recent Balance Sheet" means the balance sheet contained within
the Most Recent Financial Statements.

         "Most Recent Financial Statements" has the meaning set forth in
Section 4(c) below.

         "Most Recent Fiscal Month End" has the meaning set forth in Section
4(c) below.

         "Most Recent Fiscal Year End" has the meaning set forth in Section
4(c) below.

         "Multiemployer Plan" has the meaning set forth in ERISA Sec. 3(37).

         "Ordinary Course of Business" means the ordinary course of business of
an oncology practice similar in size to the Seller, consistent with the
Seller's past custom and practice.

         "Party" means the Purchaser or the Seller.

         "PBGC" means the Pension Benefit Guaranty Corporation.

         "Person" means an individual, a partnership, a corporation, an
association, a joint stock company, a limited liability company, a trust, a
joint venture, an unincorporated organization, or a governmental entity (or any
department, agency, or political subdivision thereof).

         "Prohibited Transaction" has the meaning set forth in ERISA Sec. 406
and Code Sec. 4975.

         "Purchase Price" has the meaning set forth in Section 2(b) below.

         "Partnership Interests" has the meaning set forth in Section 2(a)(i)
below.

         "Purchaser" has the meaning set forth in the preface above and, after
Closing (and as relates to Section 9(b) regarding indemnification), shall mean
Response Oncology, Inc. and any subsidiary or affiliate thereof.

         "Purchaser's Disclosure Letter" has the meaning set forth in Section
3(b) below.


<PAGE>   5


         "Receivables" means the accounts receivable of the Partnership as of
the close of business on the day prior to the Closing Date.

         "Reportable Event" has the meaning set forth in ERISA Sec. 4043.

         "Response Note" means the promissory note of the Purchaser payable to
the order of the Partners in the form set forth as Exhibit 2(b)(i).

         "Response Stock" means the common stock of the Purchaser, $.01 par
value per share.

         "Securities Act" means the Securities Act of 1933, as amended.

         "Securities Exchange Act" means the Securities Exchange Act of 1934,
as amended.

         "Security Interest" means any mortgage, pledge, lien, encumbrance,
charge, or other security interest, other than (a) mechanic's, materialmen's,
and similar liens, (b) liens for Taxes not yet due and payable, (C) purchase
money liens and liens securing rental payments under capital lease
arrangements, and (d) other liens arising in the Ordinary Course of Business
and not incurred in connection with the borrowing of money.

         "Seller's Disclosure Letter" has the meaning set forth in Section 3(a)
below.

         "Service Agreement" means the Service Agreement among the Purchaser,
the Partnership and the Partners to be executed and delivered by thereby, and
which will become effective, at the Closing.

         "Tangible Assets" means furniture, medical and other equipment and
leasehold improvements of the Partnership listed on Exhibit 2(a)(i)(A) hereto.

         "Tax" means any federal, state, local, or foreign income, gross
receipts, license, payroll, employment, excise, severance, stamp, occupation,
premium, windfall profits, environmental (including taxes under Code Sec. 59A),
customs duties, capital stock, franchise, profits, withholding, social security
(or similar), unemployment, disability, real property, personal property,
sales, use, transfer, registration, value added, alternative or add-on minimum,
estimated, or other tax of any kind whatsoever, including any interest,
penalty, or addition thereto, whether disputed or not.

         "Tax Return" means any return, declaration, report, claim for refund,
or information return or statement relating to Taxes, including any schedule or
attachment thereto, and including any amendment thereof.

         "Third Party Claim" has the meaning set forth in Section 9(c) below.

         "Warrants" means warrants to purchase an aggregate of 80,000 shares of
Response Stock at a price of $11.75 per share (subject to adjustment as
described in the Warrant), issuable by the Purchaser to the Partners pursuant
to Section 2(b) below, which Warrants shall be issued and delivered to the
Partners in substantially the form set forth as Exhibit 2(b)(ii) below.

         2. PURCHASE AND SALE OF PARTNERSHIP INTERESTS.

         (a) Basic Transaction.   On and subject to the terms and conditions of
this Agreement, the Purchaser and Partners agree as follows:


<PAGE>   6


                 (i) Partnership Interests. On the Closing Date, the Purchaser
shall purchase from each of the Partners, and each of the Partners shall sell
and deliver to the Purchaser, 100% of the Partnership Interests of the
Partnership (the "Partnership Interests").

                 (ii) Assumed Liabilities. In partial consideration for the
sale of the Partnership Interests by the Partners, on the Closing Date the
Purchaser shall assume and become primarily responsible for the payment or
other satisfaction of all past and future liabilities of the Partnership, and
the Partners shall be held harmless for all such liabilities, provided,
however, the Partners shall be and remain liable for:

                 (A)      all tax liabilities incurred by the Partnership
                          during the period prior to the Closing Date; and

                 (B)      any existing liability, contingent on otherwise,
                          whether known or unknown, of the Partnership not
                          disclosed to the Purchaser on Exhibit 2(a)(ii)
                          hereto. As of the Closing Date, the parties shall
                          jointly prepare and agree upon a schedule of Assumed
                          Liabilities, which shall be attached hereto as
                          Exhibit 2(a)(ii), and no Liability of the Partnership
                          which is excluded from such schedule shall be assumed
                          by the Purchaser. The Partners shall remain
                          responsible for all Liabilities not assumed by the
                          Purchaser hereunder, and shall indemnify and hold the
                          Purchaser harmless from and against any and all
                          claims, assessments, damages, Liabilities and costs
                          suffered by the Purchaser in respect of or arising
                          out of the assertion by any Person that the Purchaser
                          is responsible for any Liability of the Partnership
                          that is not an Assumed Liability.


         (b) Purchase Price; Payment and Allocation of Purchase Price. The
purchase price for the Partnership Interests shall be Nine Million Dollars
($9,000,000.00). The Purchaser shall pay or satisfy the Purchase Price in the
following manner: (i) One Hundred Fifty Thousand Dollars ($150,000.00) by
issuance and delivery of the Response Note to Allan M.  Grossman, M.D.; (ii)
Six Hundred Fifty-four Thousand One Hundred Eighty Dollars ($654,180.00) by
assumption of the Assumed Liabilities; and (iii) the balance in readily
available United States funds at Closing. As additional consideration for the
Partnership Interests, the Purchaser shall issue the Warrants to the Partners
at Closing. The parties acknowledge and agree that a portion of the purchase
price must be allocated to those types of assets described in Section 751 ("751
Assets") of the Internal Revenue Code of 1986, as amended from time to time
(the "Code") and a portion of the purchase price must be allocated to all
remaining assets ("Non 751 Assets").  The Partnership's 751 Assets consist of
certain accounts receivable and unrealized receivables of the Partnership. The
balance of the Partnership's assets consist of Non 751 Assets. For purposes of
this transaction, the parties agree to and acknowledge that $800,000 of the
consideration is allocated to 751 Assets and the balance of the consideration
$8,200,000, is allocable to Non 751 Assets. The parties further agree and
acknowledge that the allocation of $800,000.00 to 751 Assets consists of
Partnership's accounts receivable and unrealized receivables as of the date
hereof. The parties further agree that the fair market value of the furniture,
fixtures and equipment of the Partnership is $50,000, and the fair market value
of the Partnership's leasehold improvements is $1,500,000.

         (c) The Closing. The closing of the transactions contemplated by this
Agreement (the "Closing") shall take place at the offices of Bernstein, Stair &
McAdams, 530 South Gay Street, Suite 600, Knoxville, Tennessee 38902 commencing
at 9:00 a.m. local time on the second business day following the satisfaction
or waiver of all conditions precedent to the obligations of the Parties to
consummate the transactions contemplated hereby or such other date as the
Purchaser and the Partners may mutually determine (the "Closing Date");
provided, however, that the Closing Date shall be no later than June 30, 1996.

         (d) Deliveries at the Closing. At the Closing, (i) the Purchaser will
deliver to the Partners the various certificates, instruments, and documents
referred to in Section 7(a) below, (ii) the Partners will deliver to the
Purchaser the various certificates, instruments, and documents referred to in
Section 7(b) below.

<PAGE>   7

         3. REPRESENTATIONS AND WARRANTIES CONCERNING THE TRANSACTION.

         (a) Representations and Warranties of the Partners. Each of the
Partners jointly and severally represents and warrants to the Purchaser that
the statements contained in this Section 3(a) are correct and complete as of
the date of this Agreement and will be correct and complete as of the Closing
Date (as though made then and as though the Closing Date were substituted for
the date of this Agreement throughout this Section 3(a)) with respect to the
Partnership, except as set forth in the disclosure letter executed and
delivered by the Partners contemporaneous with this Agreement (the "Seller's
Disclosure Letter").  The Seller's Disclosure Letter shall be satisfactory to
the Purchaser and its counsel and will be arranged in paragraphs corresponding
to the lettered and numbered paragraphs contained in this Section 3(a) and
Section 4.

                 (i) Authorization of Transaction. Each of the Partners has the
         requisite legal capacity and has full power and authority to execute
         and deliver this Agreement and to perform his obligations hereunder.
         This Agreement constitutes the valid and legally binding obligation of
         each Partner, enforceable in accordance with its terms and conditions.
         The Partners need not give any notice to, make any filing with, or
         obtain any authorization, consent, or approval of any Person,
         government or governmental agency in order to deliver the Partnership
         Interests to the Purchaser or otherwise to consummate the transactions
         contemplated by this Agreement, or, if any such consent is required,
         each such consent has been obtained. This Agreement constitutes the
         valid and legally binding obligation of each of the Partners,
         enforceable in accordance with its terms, subject to applicable
         bankruptcy, moratorium, insolvency and other laws affecting the rights
         of creditors and general equity principles.

                 (ii) Noncontravention. Neither the execution and the delivery
         of this Agreement, nor the consummation of the transactions
         contemplated hereby, will (A) violate any constitution, statute,
         regulation, rule, injunction, judgment, order, decree, ruling, charge,
         or other restriction of any government, governmental agency, or court
         to which the Partnership or a Partner is subject or (B) conflict with,
         result in a breach of, constitute a default under, result in the
         acceleration of, create in any party the right to accelerate,
         terminate, modify, or cancel, or require any notice under any
         agreement, contract, lease, license, instrument, or other arrangement
         to which the Partnership or a Partner is a party or by which he is
         bound or to which any of his assets is subject (or result in the
         imposition of any Security Interest upon any of the Partnership's
         assets.) The Partners are not required to give any notice to, make any
         filing with, or obtain any authorization, consent or approval of any
         government or governmental agency in order for the Parties to
         consummate the transactions contemplated by this Agreement.

                 (iii) Brokers' Fees. The Partners have no Liability or
         obligation to pay any fee or commission to any broker, finder, or
         agent with respect to the transactions contemplated by this Agreement
         for which the Purchaser could become liable or obligated.

                 (iv) Title. Each of the Partners has good and marketable title
         to the Partnership Interests being conveyed to the Purchaser
         hereunder, with the sole and absolute right to sell, assign, transfer
         and convey same to the Purchaser free and clear of all liens, claims,
         options, pledges, security interests or other encumbrances.

                 (v) Existence of the Partnership. The Partnership is a general
         partnership validly existing under the laws of the State of Tennessee.
         The Partnership has the power to own its property and to carry on its
         business as now being conducted. The Partnership is duly qualified to
         do business and is in good standing in any jurisdiction in which the
         character or location of the properties owned or leased by the
         Partnership or the nature of the business conducted by the Partnership
         makes such qualification necessary.


<PAGE>   8

         (b) Representations and Warranties of the Purchaser. The Purchaser 
represents and warrants to the Partners that the statements contained in this 
Section 3(b) are correct and complete as of the date of this Agreement and 
will be correct and complete as of the Closing Date (as though made then and 
as though the Closing Date were substituted for the date of this Agreement
throughout this Section 3(b)), except as set forth in the disclosure letter
executed and delivered by the Purchaser contemporaneous with this Agreement
(the "Purchaser's Disclosure Letter").  The Purchaser's Disclosure Letter shall
be satisfactory to the Partners and their counsel.

                 (i) Organization of the Purchaser. The Purchaser is a
         corporation duly organized, validly existing, and in good standing
         under the laws of the State of Tennessee.

                 (ii) Authorization of Transaction. The Purchaser has full
         power and authority (including full corporate power and authority) to
         execute and deliver this Agreement and to perform its obligations
         hereunder. This Agreement constitutes the valid and legally binding
         obligation of the Purchaser, enforceable in accordance with its terms,
         subject to applicable bankruptcy, moratorium, insolvency and other
         laws affecting the rights of creditors and general equity principles.
         The Purchaser need not give any notice to, make any filing with, or
         obtain any authorization, consent, or approval of any Person,
         government or governmental agency in order to consummate the
         transactions contemplated by this Agreement, or, if any such consent
         is required, each such consent has been obtained.

                 (iii) Noncontravention. Neither the execution and the delivery
         of this Agreement, nor the consummation of the transactions
         contemplated hereby, will (A) violate any constitution, statute,
         regulation, rule, injunction, judgment, order, decree, ruling, charge,
         or other restriction of any government, governmental agency, or court
         to which the Purchaser is subject or any provision of its charter or
         bylaws or (B) conflict with, result in a breach of, constitute a
         default under, result in the acceleration of, create in any party the
         right to accelerate, terminate, modify, or cancel, or require any
         notice under any agreement, contract, lease, license, instrument, or
         other arrangement to which the Purchaser is a party or by which it is
         bound or to which any of its assets is subject.

                 (iv) Brokers' Fees. The Purchaser has no Liability or
         obligation to pay any fees or commissions to any broker, finder, or
         agent with respect to the transactions contemplated by this Agreement
         for which the Partners could become liable or obligated.

         4. REPRESENTATIONS AND WARRANTIES CONCERNING THE PARTNERS. Each of the
Partners, jointly and severally, represents and warrants to the Purchaser that
the statements contained in this Section 4 are true, correct and complete as of
the date of this Agreement and will be true, correct and complete as of the
Closing Date (as though made then and as though the Closing Date were
substituted for the date of this Agreement throughout this Section 4), except
as set forth in the Seller's Disclosure Letter. Nothing in the Seller's
Disclosure Letter shall be deemed adequate to disclose an exception to a
representation or warranty made herein, however, unless the Seller's Disclosure
Letter identifies the exception with reasonable particularity and describes the
relevant facts in reasonable detail. The Seller's Disclosure Letter will be
arranged in paragraphs corresponding to the lettered and numbered paragraphs
contained in this Section 4.

         (a) Power, Authority, and Partnership Matters.  The Partnership has
full power and authority and all licenses, permits, and authorizations
necessary to carry on the business in which it is engaged and to own and use
its properties. Paragraph 4(a) of the Seller's Disclosure Letter lists the
employees and partners of the Partnership. The Partners have delivered to the
Purchaser correct and complete copies of the general partnership agreement of
the Partnership (as amended to date).

         (b) Title to Assets. The Partnership has good and marketable title to,
or a valid leasehold interest in, all of its properties and assets, free and
clear of all Security Interests, and has not sold, transferred, exchanged or

<PAGE>   9

conveyed any of its properties and assets since the date of the Most Recent
Balance Sheet except for properties and assets disposed of in the Ordinary
Course of Business since the date of the Most Recent Balance Sheet.

         (c) Financial Statements. Attached as collective Paragraph 4(c) to the
Seller's Disclosure Letter are the following financial statements (collectively
the "Financial Statements"): (i) unaudited balance sheet and statement of
income, changes in partners' capital, and cash flow as of and for the fiscal
years ended December 31, 1995 (the "Most Recent Fiscal Year End") for the
Partnership; and (ii) unaudited balance sheet and statement of income (the
"Most Recent Financial Statements") as of and for the month ended March 31,
1996 (the "Most Recent Fiscal Month End") for the Partnership. The Financial
Statements (including the notes thereto) have been prepared on a consistent
basis throughout the periods covered thereby, present fairly the financial
condition of the Partnership as of such dates and the results of operations of
the Partnership for such periods, are correct and complete, and are consistent
with the books and records of the Partnership.

         (d) Events Subsequent to Most Recent Fiscal Year End. Since the Most
Recent Fiscal Year End, there has not been any adverse change in the business,
financial condition, operations, results of operations, or future prospects of
the Partnership. Without limiting the generality of the foregoing, since that
date:

                 (i) the Partnership has not sold, leased, transferred, or
         assigned any of its assets, tangible or intangible, other than for a
         fair consideration in the Ordinary Course of Business;

                 (ii) the Partnership has not entered into any agreement,
         contract, lease, or license (or series of related agreements,
         contracts, leases, and licenses) either involving more than $25,000.00
         or outside the Ordinary Course of Business;

                 (iii) no party (including the Partnership) has accelerated,
         terminated, modified, or cancelled any agreement, contract, lease, or
         license (or series of related agreements, contracts, leases, and
         licenses) involving more than $25,000.00 to which the Partnership is a
         party or by which the Partnership or its properties are bound;

                 (iv) the Partnership has not created, suffered or permitted to
         attach or be imposed any Security Interest upon any of its assets,
         tangible or intangible;

                 (v) the Partnership has not made any capital expenditure (or
         series of related capital expenditures) either involving more than
         $25,000.00 or outside the Ordinary Course of Business;

                 (vi) the Partnership has not made any capital investment in,
         any loan to, or any acquisition of the securities or assets of, any
         other Person (or series of related capital investments, loans, and
         acquisitions) either involving more than $25,000.00 or outside the
         Ordinary Course of Business;

                 (vii) the Partnership has not issued any note, bond, or other
         debt instrument or security or created, incurred, assumed, or
         guaranteed any indebtedness for borrowed money or capitalized lease
         obligation;

                 (viii) the Partnership has not delayed or postponed the
         payment of accounts payable and other Liabilities outside the Ordinary
         Course of Business;

                 (ix) the Partnership has not cancelled, compromised, waived,
         or released any right or claim (or series of related rights and
         claims) either involving more than $25,000.00 or outside the Ordinary
         Course of Business;

                 (x) the Partnership has not granted any license or sublicense
         of any rights under or with respect to any Intellectual Property;



<PAGE>   10

                 (xi) there has been no change made or authorized in the
         general partnership agreement of the Partnership;

                 (xii) none of the Partners has sold, or otherwise disposed of
         any of the Partnership Interests, granted any options, warrants, or
         other rights to purchase or obtain (including upon conversion,
         exchange, or exercise) any of the Partnership Interests;

                 (xiii) the Partnership has not declared, set aside, or paid
         any distribution with respect to its Partnership Interests (whether in
         cash or in kind) or redeemed, purchased, or otherwise acquired any of
         its Partnership Interests;

                 (xiv) the Partnership has not experienced any damage,
         destruction, or loss (whether or not covered by insurance) to its
         assets, tangible or intangible;

                 (xv) the Partnership has not made any loan to, or entered into
         any other transaction with, any of its Partners and employees outside
         the Ordinary Course of Business;

                 (xvi) the Partnership has not entered into any employment
         contract or collective bargaining agreement, written or oral, or
         modified the terms of any existing such contract or agreement;

                 (xvii) the Partnership has not granted any increase in the
         base compensation of any of its Partners and employees outside the
         Ordinary Course of Business;

                 (xviii) the Partnership has not adopted, amended, modified, or
         terminated any bonus, profit-sharing, incentive, severance, or other
         plan, contract, or commitment for the benefit of any of its Partners
         and employees (or taken any such action with respect to any other
         Employee Benefit Plan);

                 (xix) the Partnership has not made any other change in
         employment terms for any of its Partners and employees outside the
         Ordinary Course of Business;

                 (xx) the Partnership has not made or pledged to make any
         charitable or other capital contribution outside the Ordinary Course
         of Business;

                 (xxi) there has not been any other occurrence, event,
         incident, action, failure to act, or transaction outside the Ordinary
         Course of Business involving the Partnership; and

                 (xxii) the Partnership has not committed to any of the
         foregoing.

         (e) Undisclosed Liabilities. To the best of the Partners' knowledge,
the Partnership has no Liability (and there is no Basis for any present or
future action, suit, proceeding, hearing, investigation, charge, complaint,
claim, or demand against the Partnership that may result in any Liability),
except for (i) Liabilities set forth on the face of the Most Recent Balance
Sheet (rather than in any notes thereto); (ii) Liabilities which have arisen
after the Most Recent Fiscal Month End in the Ordinary Course of Business and
(iii) Liabilities described with particularity in Paragraph 4(e) of the
Seller's Disclosure Letter (none of which results from, arises out of, relates
to, is in the nature of, or was caused by any breach of contract, breach of
warranty, tort, malpractice, infringement, or violation of law).

         (f) Legal Compliance. To the best of the Partners' knowledge, the
Partnership and its predecessors and Affiliates have complied with all
applicable laws (including rules, regulations, codes, plans, injunctions,
judgments, orders, decrees, rulings, and charges thereunder) of federal, state,
local, and foreign governments (and


<PAGE>   11

all agencies thereof), and no action, suit, proceeding, hearing, investigation,
charge, complaint, claim, demand, or notice has been filed or commenced against
any of them alleging any failure so to comply.

         (g) Tax Matters.

                 (i) The Partnership has filed all Tax Returns that it was
         required to file. All such Tax Returns were correct and complete in
         all material respects. All Taxes owed by the Partnership (whether or
         not shown on any Tax Return) have been paid or accrued in the
         Financial Statements. The Partnership is not the beneficiary of any
         extension of time within which to file any Tax Return. No claim has
         ever been made by an authority in a jurisdiction where the Partnership
         does not file Tax Returns that it is or may be subject to taxation by
         that jurisdiction. There are no Security Interests on any of the
         assets of the Partnership that arose in connection with any failure
         (or alleged failure) to pay any Tax.

                 (ii) The Partnership has withheld and paid all Taxes required
         to have been withheld and paid in connection with amounts paid or
         owing to any employee, independent contractor, creditor, or other
         third party.

         (h) Real Property. The Partnership does not own any real property and
has not executed and delivered or otherwise entered into any contract to
purchase any real property. Paragraph 4(h) of the Seller's Disclosure Letter
lists and describes briefly all real property leased or subleased to the
Partnership. The Partnership has delivered to the Purchaser correct and
complete copies of the leases and subleases listed in Paragraph 4(h) of the
Seller's Disclosure Letter (as amended to date). With respect to each lease and
sublease listed in Paragraph 4(h) of the Seller's Disclosure Letter, except as
otherwise set forth in such Paragraph of the Seller's Disclosure Letter:

                 (i) the lease or sublease is legal, valid, binding,
                 enforceable, and in full force and effect;

                 (ii) the lease or sublease will continue to be legal, valid,
                 binding, enforceable, and in full force and effect on
                 identical terms following the consummation of the transactions
                 contemplated hereby;

                 (iii) no party to the lease or sublease is in breach or
                 default, and no event has occurred which, with notice or lapse
                 of time, would constitute a breach or default or permit
                 termination, modification, or acceleration thereunder;

                 (iv) no party to the lease or sublease has repudiated any
                 provision thereof;

                 (v) there are no disputes, oral agreements, or forbearance
                 programs in effect as to the lease or sublease;

                 (vi) with respect to each sublease, the representations and
                 warranties set forth in subsections (i) through (v) above are
                 true and correct with respect to the underlying lease;

                 (vii) the Partnership has not assigned, transferred, conveyed,
                 mortgaged, deeded in trust, or encumbered any interest in the
                 leasehold or subleasehold;

                 (viii) all facilities leased or subleased thereunder are
                 supplied with utilities and other services necessary for the
                 operation of said facilities; and

         (i) Intellectual Property.


<PAGE>   12

                 (i) The Partnership owns or has the right to use pursuant to 
         license, sublicense, agreement, or permission all Intellectual
         Property necessary for the operation of its business as presently
         conducted. Each item of Intellectual Property owned or used by the
         Partnership immediately prior to the Closing hereunder will be owned
         or available for use by the Partnership on identical terms and
         conditions immediately subsequent to the Closing hereunder. The
         Partnership has taken all necessary action to maintain and protect
         each item of Intellectual Property that it owns or uses. The
         Partnership has not interfered with, infringed upon, misappropriated,
         or otherwise come into conflict with any Intellectual Property rights
         of third parties, and the Partnership has not received any charge,
         complaint, claim, demand, or notice alleging any such interference,
         infringement, misappropriation, or violation (including any claim that
         the Partnership must license or refrain from using any Intellectual
         Property rights of any third party). To the Knowledge of each of the
         Partners, no third party has interfered with, infringed upon,
         misappropriated, or otherwise come into conflict with any Intellectual
         Property rights of the Partnership.

         (j) Tangible Assets. The Partnership leases all buildings, machinery,
equipment, and other tangible assets necessary for the conduct of its business
as presently conducted. Each Tangible Asset is free from patent defects, and,
to the best of the Partners' knowledge, latent defects, has been maintained in
accordance with normal industry practice, is in good operating condition and
repair (subject to normal wear and tear), and is suitable for the purposes for
which it presently is used.

         (k) Inventory. Inventory consists of pharmaceuticals and medical
supplies, all of which is merchantable and fit for the purpose for which it was
procured or manufactured, and no material portion of which is slow-moving,
obsolete, damaged, or defective, subject only to the reserve for inventory
write down set forth on the face of the Most Recent Balance Sheet (rather than
in any notes thereto) as adjusted for the passage of time through the Closing
Date in accordance with the past custom and practice of the Partnership.

         (l) Contracts. Paragraph 4(l) of the Seller's Disclosure Letter lists
the following contracts and other agreements to which the Partnership is a
party:

                 (i) any agreement (or group of related agreements) for the
         lease of personal property to or from any Person providing for lease
         payments in excess of $25,000.00 per annum;

                 (ii) any agreement (or group of related agreements) for the
         purchase or sale of pharmaceuticals, supplies, products, or other
         personal property, or for the furnishing or receipt of services, the
         performance of which will extend over a period of more than one year,
         result in a loss to the Partnership, or involve consideration in
         excess of $25,000.00;

                 (iii) any agreement concerning a partnership or joint venture
         involving the Partnership other than the Partnership's general
         partnership agreement;

                 (iv) any agreement (or group of related agreements) under
         which the Partnership has created, incurred, assumed, or guaranteed
         any indebtedness for borrowed money, or any capitalized lease
         obligation, in excess of $25,000.00 or under which it has imposed a
         Security Interest on any of its assets, tangible or intangible;

                 (v) any agreement concerning confidentiality or
         noncompetition;

                 (vi) any agreement with any health maintenance organization,
         preferred provider organization, insurance company or other third
         party payor for medical services;


<PAGE>   13

                 (vii) any profit sharing, stock option, stock purchase, stock 
         appreciation, deferred compensation, severance, or other plan or 
         arrangement for the benefit of its current or former directors, 
         officers, partners, and employees;

                 (viii) any collective bargaining agreement;

                 (ix) any agreement for the employment of any individual on a
         full-time, part-time, consulting, or other basis providing annual
         compensation in excess of $25,000.00 or providing severance benefits;

                 (x) any agreement under which the Partnership has advanced or
         loaned any amount to any of its Partners and employees outside the
         Ordinary Course of Business;

                 (xi) any agreement under which the consequences of a default
         or termination could have an adverse effect on the business, financial
         condition, operations, results of operations, or future prospects of
         the Partnership; or

                 (xii) any other agreement (or group of related agreements) the
         performance of which involves consideration in excess of $25,000.00.

The Partners have delivered to the Purchaser a correct and complete copy of
each written agreement listed in Paragraph 4(l) of the Seller's Disclosure
Letter (as amended to date) and a written summary setting forth the terms and
conditions of each oral agreement referred to in Paragraph 4(l) of the Seller's
Disclosure Letter. With respect to each such agreement: (1) the agreement is
legal, valid, binding, enforceable, and in full force and effect; (2) no party
is in breach or default, and no event has occurred which with notice or lapse
of time would constitute a breach or default, or permit termination,
modification, or acceleration, under the agreement; and (3) no party has
repudiated any provision of the agreement.

         (m) Notes and Accounts Receivable. All notes and accounts receivable
of the Partnership are reflected properly on the Partnership's books and
records, are valid receivables subject to no setoffs or counterclaims, are
current and collectible, and will be collected in accordance with their terms
at their recorded amounts, subject only to (A) contractual allowances and
adjustments to third party payors, and (B) the reserve for bad debts set forth
on the face of the Most Recent Balance Sheet (rather than in any notes thereto)
as adjusted for the passage of time through the Closing Date in accordance with
the past custom and practice of the Partnership.

         (n) Powers of Attorney. There are no outstanding powers of attorney
executed on behalf of the Partnership or the Partners.

         (o) Insurance. Paragraph 4(o) of the Seller's Disclosure Letter sets
forth the following information with respect to each insurance policy
(including policies providing property, casualty, liability, medical
malpractice, and workers' compensation coverage and bond and surety
arrangements) to which the Partnership and each of the Partners is a party, a
named insured, or otherwise the beneficiary of coverage:

                 (i) the name, address, and telephone number of the agent;

                 (ii) the name of the insurer, the name of the policyholder,
                 and the name of each covered insured;

                 (iii) the policy number and the period of coverage;

                 (iv) the scope (including an indication of whether the
         coverage was on a claims made, occurrence, or other basis) and amount
         (including a description of how deductibles and ceilings are
         calculated and operate) of coverage; and

<PAGE>   14


                 (v) a description of any retroactive premium adjustments or 
other loss-sharing arrangements.

With respect to each such insurance policy: (A) the policy is legal, valid,
binding, enforceable, and in full force and effect; (B) the Partnership, the
Partner, nor any other party to the policy is in breach or default (including
with respect to the payment of premiums or the giving of notices), and no event
has occurred which, with notice or the lapse of time, would constitute such a
breach or default, or permit termination, modification, or acceleration, under
the policy; and (C) no party to the policy has repudiated any provision
thereof. The Partnership and each of the Partners has been covered during the
past five (5) years by insurance in scope and amount customary and reasonable
for the businesses in which it has engaged during the aforementioned period.
Paragraph 4(o) of the Seller's Disclosure Letter describes any self-insurance
arrangements affecting the Partnership or the Partners.

         (p) Litigation. Section 4(p) of the Seller's Disclosure Letter sets
forth each instance in which the Partnership or any Partner (i) is subject to
any outstanding injunction, judgment, order, decree, ruling, or charge or (ii)
is a party or is threatened to be made a party to any action, suit, proceeding,
hearing, or investigation of, in, or before any court or quasi-judicial or
administrative agency of any federal, state, local, or foreign jurisdiction or
before any arbitrator. None of the actions, suits, proceedings, hearings, and
investigations set forth in Section 4(p) of the Seller's Disclosure Letter
could result in any material adverse change in the business, financial
condition, operations, results of operations, or future prospects of the
Partnership or the medical practice to be conducted by the Partners following
the Closing. Each of the Partners has no reason to believe that any such
action, suit, proceeding, hearing, or investigation may be brought or
threatened against the Partnership or any Partner.

         (q) Employees. To the Knowledge of each of the Partners, no executive,
key employee, or group of employees has any plans to terminate employment with
the Partnership. The Partnership is not a party to or bound by any collective
bargaining agreement, nor has it experienced any strikes, grievances, claims of
unfair labor practices, or other collective bargaining disputes. The
Partnership has not committed any unfair labor practice. Each of the Partners
has no Knowledge of any organizational effort presently being made or
threatened by or on behalf of any labor union with respect to employees of the
Partnership. Except as described in paragraph 4(q) of the Seller's Disclosure
Letter, each of the Partners has no knowledge of any disciplinary or other
proceeding alleging professional misconduct or misfeasance against any employee
of the Partnership.

         (r) Employee Benefits.

                 (i) Paragraph 4(r) of the Seller's Disclosure Letter lists
         each Employee Benefit Plan that the Partnership maintains or to which
         the Partnership contributes.

                          (A) Each such Employee Benefit Plan (and each related
                 trust, insurance contract, or fund) complies in form and in
                 operation in all respects with the applicable requirements of
                 ERISA, the Code, and other applicable laws.

                          (B) All required reports and descriptions (including
                 Form 5500 Annual Reports, Summary Annual Reports, PBGC-1's,
                 and Summary Plan Descriptions) have been filed or distributed
                 appropriately with respect to each such Employee Benefit Plan.
                 The requirements of Part 6 of Subtitle B of Title I of ERISA
                 and of Code Sec. 4980B have been met with respect to each such
                 Employee Benefit Plan which is an Employee Welfare Benefit
                 Plan.

                          (C) All contributions (including all employer
                 contributions and employee salary reduction contributions)
                 which are due have been paid to each such Employee Benefit
                 Plan which is an Employee Pension Benefit Plan and all
                 contributions for any period ending on or before the Closing
                 Date which are not yet due have been paid to each such
                 Employee Pension Benefit Plan or accrued in accordance with
                 the past custom and practice of the Partnership. All premiums
                 or


<PAGE>   15

                 other payments for all periods ending on or before the Closing
                 Date have been paid with respect to each such Employee Benefit
                 Plan which is an Employee Welfare Benefit Plan.

                          (D) Each such Employee Benefit Plan which is an
                 Employee Pension Benefit Plan meets the requirements of a
                 "qualified plan" under Code Sec. 401(a) and has received,
                 within the last two years, a favorable determination letter
                 from the Internal Revenue Service.

                          (E) The market value of assets under each such
                 Employee Benefit Plan which is an Employee Pension Benefit
                 Plan (other than any Multiemployer Plan) equals or exceeds the
                 present value of all vested and nonvested Liabilities
                 thereunder determined in accordance with PBGC methods,
                 factors, and assumptions applicable to an Employee Pension
                 Benefit Plan terminating on the date for determination.

                          (F) The Partners have delivered to the Purchaser
                 correct and complete copies of the plan documents and summary
                 plan descriptions, the most recent determination letter
                 received from the Internal Revenue Service, the most recent
                 Form 5500 Annual Report, and all related trust agreements,
                 insurance contracts, and other funding agreements which
                 implement each such Employee Benefit Plan.

                 (ii) With respect to each Employee Benefit Plan that the
         Partnership maintains or ever has maintained or to which it
         contributes, ever has contributed, or ever has been required to
         contribute:

                          (A) No such Employee Benefit Plan which is in
                 Employee Pension Benefit Plan (other than any Multiemployer
                 Plan) has been completely or partially terminated or been the
                 subject of a Reportable Event as to which notices would be
                 required to be filed with the PBGC. No proceeding by the PBGC
                 to terminate any such Employee Pension Benefit Plan (other
                 than any Multiemployer Plan) has been instituted or
                 threatened.

                          (B) There have been no Prohibited Transactions with
                 respect to any such Employee Benefit Plan.  No Fiduciary has
                 any Liability for breach of fiduciary duty or any other
                 failure to act or comply in connection with the administration
                 or investment of the assets of any such Employee Benefit Plan.
                 No action, suit, proceeding, hearing, or investigation with
                 respect to the administration or the investment of the assets
                 of any such Employee Benefit Plan (other than routine claims
                 for benefits) is pending or threatened. Each of the Partners
                 has no Knowledge of any Basis for any such action, suit,
                 proceeding, hearing, or investigation.

                          (C) The Partnership has not incurred, and neither the
                 Partnership nor the Partners (and employees with
                 responsibility for employee benefits matters) of the
                 Partnership has any reason to expect that the Partnership will
                 incur, any Liability to the PBGC (other than PBGC premium
                 payments) or otherwise under Title IV of ERISA (including any
                 withdrawal Liability) or under the Code with respect to any
                 such Employee Benefit Plan which is an Employee Pension
                 Benefit Plan.

                 (iii) The Partnership does not contribute to, has never
         contributed to, or has not been required to contribute to any
         Multiemployer Plan or has any Liability (including withdrawal
         Liability) under any Multiemployer Plan.

                 (iv) The Partnership does not maintain or has never maintained
         or contributes, ever has contributed, or has not been required to
         contribute to any Employee Welfare Benefit Plan providing medical,
         health, or life insurance or other welfare-type benefits for current
         or future retired or terminated employees, their spouses, or their
         dependents (other than in accordance with Code Section 4980B).


<PAGE>   16


         (s) Guaranties. The Partnership is not a guarantor or is not otherwise
liable for any Liability or obligation (including indebtedness) of any other
Person.

         (t) Environment, Health, and Safety. To the best of the Partners'
knowledge:

                 (i) Each of the Partnership and its predecessors and
         Affiliates has complied with all Environmental, Health, and Safety
         Laws, and no action, suit, proceeding, hearing, investigation, charge,
         complaint, claim, demand, or notice has been filed or commenced
         against any of them alleging any failure so to comply. Without
         limiting the generality of the preceding sentence, each of the
         Partnership and its predecessors and Affiliates has obtained and been
         in compliance with all of the terms and conditions of all permits,
         licenses, and other authorizations which are required under, and has
         complied with all other limitations, restrictions, conditions,
         standards, prohibitions, requirements, obligations, schedules, and
         timetables which are contained in, all Environmental, Health, and
         Safety Laws.

                 (ii) The Partnership has no Liability (and none of the
         Partnership and its predecessors and Affiliates has handled or
         disposed of any substance, arranged for the disposal of any substance,
         exposed any employee or other individual to any substance or
         condition, or owned or operated any property or facility in any manner
         that could form the Basis for any present or future action, suit,
         proceeding, hearing, investigation, charge, complaint, claim, or
         demand against the Partnership giving rise to any Liability) for
         damage to any site, location, or body of water (surface or
         subsurface), for any illness of or personal injury to any employee or
         other individual, or for any reason under any Environmental, Health,
         and Safety Law.

                 (iii) All properties and equipment used in the business of the
         Partnership and its predecessors and Affiliates have been free of
         asbestos, PCB's, methylene chloride, trichloroethylene,
         1,2-trans-dichloroethylene, dioxins, dibenzofurans, and Extremely
         Hazardous Substances.

         (u) Healthcare Compliance. Neither the Partnership nor any Partner or
other physician associated with or employed by the Partnership has received
payment or any remuneration whatsoever to induce or encourage the referral of
patients or the purchase of goods and/or services as prohibited under 42 U.S.C.
Section 1320a-7b(b), or otherwise perpetrated any Medicare or Medicaid fraud
or abuse nor has any fraud or abuse been alleged within the last five (5) years
by any government agency. The Partnership (and/or each Partner or other
physician employed thereby) is participating in or is otherwise authorized to
receive reimbursement from or is a party to Medicare, Medicaid, and other
third-party payor programs. All necessary certifications and contracts required
for participation in such programs are in full force and effect and have not
been amended or otherwise modified, rescinded, revoked or assigned and no
condition exists or event has occurred which in itself or with the giving of
notice or the lapse of time or both would result in the suspension, revocation,
impairment, forfeiture or non-renewal of any such third party payor program.
The Partnership is in full compliance with the requirements of all such third
party payor programs applicable thereto.

         (v) Fraud and Abuse. The Partnership and persons and entities
providing professional services for the Partnership have not engaged in any
activities which are prohibited under 42 U.S.C. Section 1320a-7b, or the
regulations promulgated thereunder pursuant to such statutes, or related state
or local statutes or regulations, or which are prohibited by rules of
professional conduct, including but not limited to the following:

                 (i) knowingly and willfully making or causing to be made a
         false statement or representation of a material fact in any
         application for any benefit or payment;

                 (ii) knowingly and willfully making or causing to be made any
         false statement or representation of a material fact for use in
         determining rights to any benefit or payment;


<PAGE>   17

                 (iii) failing to disclose knowledge by a claimant of the
         occurrence of any event affecting the initial or continued right to
         any benefit or payment on its own behalf or on behalf of another, with
         intent to fraudulently secure such benefit or payment; and

                 (iv) knowingly and willfully soliciting or receiving any
         remuneration (including any kickback, bribe, or rebate), directly or
         indirectly, overtly or covertly, in cash or in kind or offering to pay
         or receive such remuneration (A) in return for referring an individual
         to a person for the furnishing or arranging for the furnishing or any
         item or service for which payment may be made in whole or in part by
         Medicare or Medicaid, or (B) in return for purchasing, leasing, or
         ordering or arranging for or recommending purchasing, leasing, or
         ordering any good, facility, service or item for which payment may be
         made in whole or in part by Medicare or Medicaid.

         (w) Facility Compliance. The Partnership is duly licensed, and the
Partnership and its clinics, offices and facilities are lawfully operated in
accordance with the requirements of all applicable law and has all necessary
authorizations for the use and operation, all of which are in full force and
effect. There are no outstanding notices of deficiencies relating to the
Partnership issued by any governmental authority or third party payor requiring
conformity or compliance with any applicable law or condition for participation
of such governmental authority or third party payor, and after reasonable and
independent inquiry and due diligence and investigation, none of the Partners
has received notice of and has no Knowledge of or reason to believe that such
necessary authorizations may be revoked or not renewed in the ordinary course.

         (x) Rates and Reimbursement Policies. The Partnership has no rate
appeal currently pending before any governmental authority or any administrator
of any third party payor program.

         (y) Disclosure. The representations and warranties contained in this
Section 4 and in the Seller's Disclosure Letter do not contain any untrue
statement of a fact or omit to state any fact necessary in order to make the
statements and information contained in this Section 4 or the Seller's
Disclosure Letter not misleading in any material respect.

         5. POST-CLOSING COVENANTS. The Parties agree as follows with respect
to the period following the Closing.

         (a) General. In case at any time after the Closing any further action
is necessary to carry out the purposes of this Agreement, each of the Parties
will take such further action (including the execution and delivery of such
further instruments and documents) as any other Party may reasonably request,
all at the sole cost and expense of the requesting Party (unless the requesting
Party is entitled to indemnification therefor under Section 8 below). Each of
the Partners acknowledges and agrees that from and after the Closing the
Purchaser will be entitled to possession of all documents, books, records
(including Tax records), agreements, and financial data of any sort relating to
the Partnership. The Partners will be afforded access to such documents, books,
records, agreements and financial data for inspection and copying during
ordinary business hours.

         (b) Litigation Support. In the event and for so long as any Party
actively is contesting or defending against any action, suit, proceeding,
hearing, investigation, charge, complaint, claim, or demand in connection with
(i) any transaction contemplated under this Agreement or (ii) any fact,
situation, circumstance, status, condition, activity, practice, plan,
occurrence, event, incident, action, failure to act, or transaction on or prior
to the Closing Date involving the Partnership, each of the other Parties will
cooperate with him or it and his or its counsel in the contest or defense, make
available their personnel, and provide such testimony and access to their books
and records as shall be necessary in connection with the contest or defense,
all at the sole cost and expense of the contesting or defending Party (unless
the contesting or defending Party is entitled to indemnification therefor under
Section 8 below).


<PAGE>   18

         (c) Transition. The Partners will not take any action that is designed
or intended to have the effect of discouraging any lessor, licensor, supplier,
or other business associate of the Partnership from maintaining the same
business relationships with the Purchaser after the Closing as it maintained
with the Partnership prior to the Closing.  The Partners will refer all
inquiries relating to the businesses of the Partnership to the Purchaser from
and after the Closing.

         (d) Employees. The Partnership shall continue to employ, at
substantially the same pay rates and benefit levels as paid or delivered by the
Partnership, the persons listed on Exhibit 5(d) attached hereto.

         (e) Amendment of Partnership Agreement. The Partners will cause the
general partnership agreement to be amended removing the Partners and adding
the Purchaser as the new partner of the Partnership.

         6. CONDITIONS PRECEDENT TO OBLIGATION TO CLOSE.

         (a) Conditions to Obligation of the Purchaser. The obligation of the
Purchaser to consummate the transactions to be performed by it in connection
with the Closing is subject to satisfaction of the following conditions:

                 (i) the representations and warranties set forth in Section
         3(a) and Section 4 above shall be true and correct in all material
         respects at and as of the Closing Date;

                 (ii) the Partners shall have performed and complied with all
         of the covenants hereunder in all material respects through the
         Closing;

                 (iii) the Partners shall have given such notices to persons,
         governments and governmental agencies and shall have procured from
         third parties all consents to consummation of the transactions
         contemplated hereby that may be required by law or the terms of any
         contract to which the Partnership or any Partner may be subject or
         that the Purchaser may reasonably request in connection with the
         transactions contemplated hereby;

                 (iv) no action, suit, or proceeding shall be pending or
         threatened before any court or quasi-judicial or administrative agency
         of any federal, state, local, or foreign jurisdiction or before any
         arbitrator wherein an unfavorable injunction, judgment, order, decree,
         ruling, or charge would (A) prevent consummation of any of the
         transactions contemplated by this Agreement, (B) cause any of the
         transactions contemplated by this Agreement to be rescinded following
         consummation, (C) affect adversely the right of the Purchaser to
         acquire Partnership Interests and own and operate the Partnership and
         enter into the Service Agreement, or (D) affect adversely the right of
         the Partnership to own its assets and to operate its businesses (and
         no such injunction, judgment, order, decree, ruling, or charge shall
         be in effect);

                 (v) each of the Partners shall have delivered to the Purchaser
         a certificate to the effect that each of the conditions specified
         above in Section 6(a)(i)-(iv) is satisfied in all respects;

                 (vi) the Purchaser shall have received from Bernstein, Stair &
         McAdams, counsel to the Partners, an opinion as to matters customarily
         addressed in opinions of counsel in transactions such as that
         described herein, which opinion shall be in form and substance
         reasonably acceptable to the Purchaser and its counsel;

                 (vii) the Partners and Knoxville Hematology-Oncology
         Associates, P.L.L.C. (the "Continuing Practice") shall have executed
         and delivered to the Purchaser the Service Agreement in substantially
         the form set forth as Exhibit 6(a)(vii) hereof;


<PAGE>   19

                 (viii) the Purchaser shall have received an opinion from
         Tennessee counsel reasonably satisfactory to the Purchaser that the
         Service Agreement is the legal, valid and binding obligation of the
         Partners and the Continuing Practice, enforceable according to its
         terms (subject to standard bankruptcy, insolvency and principles of
         equity exceptions) and that the performance of the Service Agreement
         by the Purchaser, the Partners and the Continuing Practice will not
         violate any statute, regulation, official interpretation, order,
         decree or other law of the state of Tennessee;

                 (ix) each Partner shall have executed an employment contract
         with the Continuing Practice in substantially the form set forth as
         Exhibit 6(a)(x) hereto; and

                 (x) all actions to be taken by each of the Partners and the
         Partnership in connection with consummation of the transactions
         contemplated hereby and all certificates, opinion, instruments, and
         other documents required to effect the transactions contemplated
         hereby will be satisfactory in form and substance to the Purchaser.

The Purchaser may waive any condition specified in this Section 6(a) if it
executes a writing so stating at or prior to the Closing.

         (b) Conditions to Obligation of the Partners. The obligation of the
Partners to consummate the transactions to be performed by them in connection
with the Closing is subject to satisfaction of the following conditions:

                 (i) the representations and warranties set forth in Section
         3(b) above shall be true and correct in all material respects at and
         as of the Closing Date;

                 (ii) the Purchaser shall have performed and complied with all
         of its covenants hereunder in all material respects through the
         Closing;

                 (iii) no action, suit, or proceeding shall be pending or
         threatened before any court or quasi-judicial or administrative agency
         of any federal, state, local, or foreign jurisdiction or before any
         arbitrator wherein an unfavorable injunction, judgment, order, decree,
         ruling, or charge would (A) prevent consummation of any of the
         transactions contemplated by this Agreement or (B) cause any of the
         transactions contemplated by this Agreement to be rescinded following
         consummation (and no such injunction, judgment, order, decree, ruling,
         or charge shall be in effect);

                 (iv) the Purchaser shall have delivered to the Partners a
         certificate to the effect that each of the conditions specified above
         in Section 6(b)(i)-(iii) is satisfied in all respects;

                 (v) the Partners shall have received an opinion from Baker,
         Donelson, Bearman & Caldwell that the performance of the Service
         Agreement by the Purchaser, the Partners and the Continuing Practice
         will not violate any statute, regulation, official interpretation,
         order, decree or other law of the United States of America; and

                 (vi) all actions to be taken by the Purchaser in connection
         with consummation of the transactions contemplated hereby and all
         certificates, instruments, and other documents required to effect the
         transactions contemplated hereby will be reasonably satisfactory in
         form and substance to the Partners.

The Partners may waive any condition specified in this Section 6(b) if they
execute a writing so stating at or prior to the Closing.


<PAGE>   20

         7. DELIVERIES AT CLOSING.

         (a) Documents to be Delivered by the Purchaser. At the Closing, the
Purchaser shall deliver the following instruments and documents to the Partners
or other appropriate party:

                 (i) a certified or cashier's check or wire transfer equal to
         the amount of cash deliverable by the Purchaser pursuant to Section
         2(b);

                 (ii) the Response Note, payable to the order of Allan M.
         Grossman, M.D.; 

                 (iii) the Warrants, in denominations of 20,000 Warrants each;

                 (iv) the certificate described in Section 6(b)(iv) above;

                 (v) the opinion described in Section 6(b)(v) above; and

                 (vi) such other documents as the Partners may reasonably
         request to affect the transactions contemplated by this Agreement.

         (b) Documents to be Delivered by the Partners. At the Closing, the
Partners shall deliver the following instruments and documents to the
Purchaser:

                 (i) all consents necessary regarding the transaction
         contemplated by this Agreement;

                 (ii) the opinion of counsel to the Partnership, in a form
         reasonably satisfactory to the Purchaser's counsel, required by
         Section 6(a)(vi) above;

                 (iii) the opinion, in a form reasonably acceptable to the
         Purchaser's counsel, required by Section 6(a)(viii) above;

                 (iv) the Certificate described in Section 6(a)(v) above;

                 (v) the Service Agreement, duly executed by the Partners and
         any entity in which they shall conduct a medical practice after
         Closing; and

                 (vi) such other documents as may be required or as the
         Purchaser may reasonably request to affect the transactions
         contemplated by this Agreement.

         8. REMEDIES FOR BREACHES OF THIS AGREEMENT.

         (a) Survival of Representations and Warranties. All of the
representations and warranties of the Parties contained in this Agreement shall
survive the Closing hereunder (even if the damaged Party knew or had reason to
know of any misrepresentation or breach of warranty at the time of Closing) and
continue in full force and effect for a period of two (2) years (subject to any
applicable statutes of limitations).

         (b) Indemnification Provisions for Benefit of the Purchaser. In the
event any of the Partners breaches (or in the event any third party alleges
facts that, if true, would mean a Partner has breached) any of the
representations, warranties, and covenants contained herein and, provided that
the Purchaser makes a written claim for indemnification against the Partners
pursuant to Section 8(c)(i) below, then each of the Partners, jointly and
severally, agree to indemnify the Purchaser from and against the entirety of
any Adverse Consequences the Purchaser may suffer through and after the date of
the claim for indemnification (including any Adverse Consequences the Purchaser
may suffer after the end of any applicable survival period, provided that the
Purchaser


<PAGE>   21

shall have made a reasonable claim for indemnification hereunder prior to the
end of such survival period) resulting from, arising out of, relating to, in
the nature of, or caused by the breach (or the alleged breach) or otherwise.

         (c) Matters Involving Third Parties.

                 (i) If any third party shall notify the Purchaser with respect
         to any matter (a "Third Party Claim") which may give rise to a claim
         for indemnification under this Section 8, then the Purchaser shall
         promptly notify the Partners thereof in writing; provided, however,
         that no delay on the part of the Purchaser in notifying the Partners
         shall relieve the indemnitor from any obligation hereunder unless (and
         then solely to the extent) the indemnitor thereby is prejudiced.

                 (ii) The Partners will have the right to defend the Purchaser
         against the Third Party Claim with counsel of their choice reasonably
         satisfactory to the Purchaser so long as (A) the Partners indemnify
         the Purchaser in accordance with this Section 8.

                 (iii) So long as the Partners are conducting the defense of
         the Third Party Claim in accordance with Section 8(c)(ii) above, (A)
         the Purchaser may retain separate co-counsel at its sole cost and
         expense and participate in the defense of the Third Party Claim, (B)
         the Purchaser will not consent to the entry of any judgment or enter
         into any settlement with respect to the Third Party Claim without the
         prior written consent of the Partners (not to be withheld
         unreasonably), and (C) the Partners will not consent to the entry of
         any judgment or enter into any settlement with respect to the Third
         Party Claim without the prior written consent of the Purchaser.

                 (iv) In the event any of the conditions in Section 8(c)(ii)
         above is or becomes unsatisfied, however, (A) the Purchaser may defend
         against, and consent to the entry of any judgment or enter into any
         settlement with respect to, the Third Party Claim in any manner it may
         deem appropriate (and the Purchaser need not consult with, or obtain
         any consent from, the Partners in connection therewith), (B) the
         Partners will reimburse the Purchaser promptly and periodically for
         the costs of defending against the Third Party Claim (including
         attorneys' fees and expenses), and (C) the Partners will remain
         responsible for any Adverse Consequences the Purchaser may suffer
         resulting from, arising out of, relating to, in the nature of, or
         caused by the Third Party Claim to the fullest extent provided in this
         Section 8.

         (d) Determination of Adverse Consequences. The Parties shall take into
account the time cost of money (using the Applicable Rate as the discount rate)
in determining Adverse Consequences for purposes of this Section 8. All
indemnification payments under this Section 8 shall be deemed adjustments to
the Purchase Price.

         (e) Recoupment Under the Response Note. If and only to the extent that
the Partners shall not have satisfied any indemnification obligation pursuant
hereto within ninety (90) days after the Purchaser shall have made written
demand therefor, the Purchaser shall have the option of recouping all or any
part of any Adverse Consequences it shall have suffered by notifying the
Partners that the Purchaser is reducing the principal amount outstanding under
the Response Note held by the Partners. This shall affect the timing and amount
of payments required under the Response Note in the same manner as if the
Purchaser had made a permitted prepayment (without premium or penalty)
thereunder.

         (f) Other Indemnification Provisions. The foregoing indemnification
provisions are in addition to, and not in derogation of, any statutory,
equitable, or common law remedy any Party may have for breach of
representation, warranty, or covenant.

         9. TERMINATION.

<PAGE>   22

         (a) Termination of Agreement. Certain of the Parties may terminate 
this Agreement as provided below:

                 (i) the Purchaser and the Partners may terminate this
         Agreement by mutual written consent at any time prior to the Closing;

                 (ii) the Purchaser may terminate this Agreement by giving
         written notice to the Partners at any time prior to the Closing (A) in
         the event any of the Partners has breached any material
         representation, warranty, or covenant contained in this Agreement in
         any material respect, the Purchaser has notified the Partners of the
         breach, and the breach has continued without cure for a period of 10
         days after the notice of breach or (B) if the Closing shall not have
         occurred on or before June 30, 1996, by reason of the failure of any
         condition precedent under Section 6(a) hereof (unless the failure
         results primarily from the Purchaser itself breaching any
         representation, warranty, or covenant contained in this Agreement);
         and

                 (iii) the Partners may terminate this Agreement by giving
         written notice to the Purchaser at any time prior to the Closing (A)
         in the event the Purchaser has breached any material representation,
         warranty, or covenant contained in this Agreement in any material
         respect, the Partners have notified the Purchaser of the breach, and
         the breach has continued without cure for a period of 10 days after
         the notice of breach or (B) if the Closing shall not have occurred on
         or before June 30, 1996 by reason of the failure of any condition
         precedent under Section 6(b) hereof (unless the failure results
         primarily from any of the Partners themselves breaching any
         representation, warranty, or covenant contained in this Agreement).

         (b) Effect of Termination. If any Party terminates this Agreement
pursuant to Section 9(a) above, all rights and obligations of the Parties
hereunder shall terminate without any Liability of any Party to any other Party
(except for any Liability of any Party then in breach).

         10. MISCELLANEOUS.

         (a) Press Releases and Public Announcements. No Party shall issue any
press release or make any public announcement relating to the subject matter of
this Agreement without the prior written approval of the Purchaser and the
Partners; provided, however, that any Party may make any public disclosure it
believes in good faith is required by applicable law or any listing or trading
agreement concerning its publicly-traded securities (in which case the
disclosing Party will use its best efforts to advise the other Parties prior to
making the disclosure).

         (b) No Third-Party Beneficiaries. This Agreement shall not confer any
rights or remedies upon any Person other than the Parties and their respective
successors and permitted assigns.

         (c) Entire Agreement. This Agreement (including the documents referred
to herein) constitutes the entire agreement among the Parties and supersedes
any prior understandings, agreements, or representations by or among the
Parties, written or oral, to the extent they related in any way to the subject
matter hereof.

         (d) Succession and Assignment. This Agreement shall be binding upon
and inure to the benefit of the Parties named herein and their respective
successors and permitted assigns. No Party may assign either this Agreement or
any of his or its rights, interests, or obligations hereunder without the prior
written approval of the Purchaser and the Partners; provided, however, that the
Purchaser may (i) assign any or all of its rights and interests hereunder to
one or more of its Affiliates and (ii) designate one or more of its Affiliates
to perform its obligations hereunder (in any or all of which cases the
Purchaser nonetheless shall remain responsible for the performance of all of
its obligations hereunder).

         (e) Counterparts. This Agreement may be executed in one or more
counterparts, each of which shall be deemed an original but all of which
together will constitute one and the same instrument.


<PAGE>   23

         (f) Headings. The section headings contained in this Agreement are
inserted for convenience only and shall not affect in any way the meaning or
interpretation of this Agreement.

         (g) Notices. All notices, requests, demands, claims, and other
communications hereunder will be in writing. Any notice, request, demand,
claim, or other communication hereunder shall be deemed duly given if (and then
two business days after) it is sent by registered or certified mail, return
receipt requested, postage prepaid, and addressed to the intended recipient as
set forth below:

<TABLE>
         <S>                                                        <C>
         If to the Partners:                                        Copy to:

         Knoxville Hematology Oncology Associates                   James W. Parris, Esq.
         1114 Weisgarber Road, #E                                   Bernstein, Stair & McAdams
         Knoxville, Tennessee 37909-2648                            530 South Gay Street, Suite 600
                                                                    Knoxville, Tennessee 38902


         If to the Purchaser:                                       Copy to:

         Daryl P. Johnson                                           John A. Good, Esq.
         Response Oncology, Inc.                                    Executive Vice President -General Counsel
         1775 Moriah Woods Blvd.                                    Response Oncology, Inc.
         Memphis, Tennessee 38117                                   1775 Moriah Woods Blvd.
                                                                    Memphis, TN 38117
</TABLE>


Any Party may send any notice, request, demand, claim, or other communication
hereunder to the intended recipient at the address set forth above using any
other means (including personal delivery, expedited courier, messenger service,
telecopy, telex, ordinary mail, or electronic mail), but no such notice,
request, demand, claim, or other communication shall be deemed to have been
duly given unless and until it actually is received by the intended recipient.
Any Party may change the address to which notices, requests, demands, claims,
and other communications hereunder are to be delivered by giving the other
Parties notice in the manner herein set forth.

         (h) Governing Law. This Agreement shall be governed by and construed
in accordance with the domestic laws of the State of Tennessee without giving
effect to any choice or conflict of law provision or rule (whether of the State
of Tennessee or any other jurisdiction) that would cause the application of the
laws of any jurisdiction other than the State of Tennessee.

         (i) Amendments and Waivers. No amendment of any provision of this
Agreement shall be valid unless the same shall be in writing and signed by the
Purchaser and the Partners. No waiver by any Party of any default,
misrepresentation, or breach of warranty or covenant hereunder, whether
intentional or not, shall be deemed to extend to any prior or subsequent
default, misrepresentation, or breach of warranty or covenant hereunder or
affect in any way any rights arising by virtue of any prior or subsequent such
occurrence.

         (j) Severability. Any term or provision of this Agreement that is
invalid or unenforceable in any situation in any jurisdiction shall not affect
the validity or enforceability of the remaining terms and provisions hereof or
the validity or enforceability of the offending term or provision in any other
situation or in any other jurisdiction.

         (k) Expenses. Each of the Parties will bear his or its own costs and
expenses (including legal fees and expenses) incurred in connection with this
Agreement and the transactions contemplated hereby.


<PAGE>   24

         (l) Construction. The Parties have participated jointly in the
negotiation and drafting of this Agreement. In the event an ambiguity or
question of intent or interpretation arises, this Agreement shall be construed
as if drafted jointly by the Parties and no presumption or burden of proof
shall arise favoring or disfavoring any Party by virtue of the authorship of
any of the provisions of this Agreement. Any reference to any federal, state,
local, or foreign statute or law shall be deemed also to refer to all rules and
regulations promulgated thereunder, unless the context requires otherwise. The
word "including" shall mean including without limitation. The Parties intend
that each representation, warranty, and covenant contained herein shall have
independent significance. If any Party has breached any representation,
warranty, or covenant contained herein in any respect, the fact that there
exists another representation, warranty, or covenant relating to the same
subject matter (regardless of the relative levels of specificity) which the
Party has not breached shall not detract from or mitigate the fact that the
Party is in breach of the first representation, warranty, or covenant.

         (m) Incorporation of Exhibits and Schedules. The Exhibits and
Schedules identified in this Agreement are incorporated herein by reference and
made a part hereof.

         (n) Specific Performance. Each of the Parties acknowledges and agrees
that the other Parties would be damaged irreparably in the event any of the
provisions of this Agreement are not performed in accordance with their
specific terms or otherwise are breached. Accordingly, each of the Parties
agrees that the other Parties shall be entitled to an injunction or injunctions
to prevent breaches of the provisions of this Agreement and to enforce
specifically this Agreement and the terms and provisions hereof in any action
instituted in any court of the United States or any state thereof having
jurisdiction over the Parties and the matter, in addition to any other remedy
to which they may be entitled, at law or in equity.

         (o) Submission to Jurisdiction. Each of the Parties submits to the
jurisdiction of any state or federal court sitting in Knoxville, Knox County,
Tennessee in any action or proceeding arising out of or relating to this
Agreement and agrees that all claims in respect of the action or proceeding may
be heard and determined in any such court. Each Party also agrees not to bring
any action or proceeding arising out of or relating to this Agreement in any
other court.  Each of the Parties waives any defense of inconvenient forum to
the maintenance of any action or proceeding so brought and waives any bond,
surety, or other security that might be required of any other Party with
respect thereto. Nothing in this Section 11(p), however, shall affect the right
of any Party to bring any action or proceeding arising out of or relating to
this Agreement in any other court or to serve legal process in any other manner
permitted by law or at equity. Each Party agrees that a final judgment in any
action or proceeding so brought shall be conclusive and may be enforced by suit
on the judgment or in any other manner provided by law or at equity.


                              *   *   *   *   *

<PAGE>   25


          IN WITNESS WHEREOF, the Parties hereto have executed this Agreement 
on [as of] the date first above written.


                                  PURCHASER:
                                  
                                  Response Oncology, Inc.
                                  
                                  
                                  By:
                                     ------------------------------------------
                                  Title:
                                        ---------------------------------------

                                  
                                  Knoxville Hematology Oncology Associates
                                  
                                  
                                  By:
                                     ------------------------------------------
                                  Title:
                                        ---------------------------------------

                                  Partners:
                                  
                                  
                                  ---------------------------------------------
                                  Peter W. Carter, M.D.
                                  
                                  
                                  ---------------------------------------------
                                  Albert S.C. Ebenezer, M.D.
                                  
                                  
                                  ---------------------------------------------
                                  Jerry M. Foster, M.D.
                                  
                                  
                                  ---------------------------------------------
                                  Allan M. Grossman, M.D.


<PAGE>   26


                               Exhibit 2(a)(ii)

                             Assumed Liabilities

Accounts Payable (Per List Provided by the Partnership)         $563,295.00

Capital Lease Obligations                                         90,885.00
                                                                -----------
Total Assumed Liabilities                                       $654,180.00
                                                                ===========


<PAGE>   27


                                Exhibit 2(b)(i)
                                       to
                          Purchase and Sale Agreement


                         NON-NEGOTIABLE PROMISSORY NOTE

$150,000.00                                          Knoxville, Tennessee
                                                     April 12, 1996


         FOR VALUE RECEIVED, the undersigned, RESPONSE ONCOLOGY, INC., a
Tennessee corporation (the "Maker"), promises to pay to the order of ALLAN M.
GROSSMAN, M.D., (the "Lender"), the principal sum of ONE HUNDRED FIFTY THOUSAND
DOLLARS ($150,000.00), together with interest from date until maturity at the
rate of five (5%) percent per annum from date until Maturity (hereinafter
defined). Interest shall be payable on the unpaid principal balance hereof, in
arrears, at Maturity. The principal amount of this note shall be payable in
full on April 12, 1997 ("Maturity").

         This Note may be prepaid in whole or in part prior to Maturity upon
sixty (60) days advance written notice given by the Maker to the Lender. Any
partial prepayment of principal shall, however, not have the effect of
suspending or deferring the payments provided for herein, but the same shall
continue to be due and payable on each due date subsequent to any such partial
prepayment of the principal and shall operate to effect full payment of the
principal at an earlier date.

         At the option of the Lender, exercisable not later than ten (10) days
prior to any payment of principal (including any prepayment) or interest on
this Note, such payment shall be paid in whole or in part in whole shares of
common stock of the Maker, $.01 par value per share (the "Shares")  .For
purposes of this paragraph, the number of whole Shares to which the Lender
shall be entitled upon exercise of the option provided hereunder shall be
determined by dividing the amount of principal and interest to be paid in
Shares by the Maker by $11.75, which price shall be adjusted for stock splits,
stock dividends, reverse stock splits, recapitalizations, reorganizations and
other changes in the capital structure of the Maker affecting the value of the
Shares. No fractional Shares shall be issued by the Maker, and the Lender shall
be paid cash in lieu of such fractional Shares in an amount equal to the
fractional Share to which the Lender would otherwise be entitled times the
conversion price stated above.

         Any amounts not paid when due hereunder (whether by acceleration or
otherwise) shall bear interest after maturity at the lesser of (a) eighteen
percent (18%) per annum or (b) the maximum effective contract rate which may be
charged by the Lender under applicable law from time to time in effect.

         In the event that the foregoing provisions should be construed by a
court of competent jurisdiction not to constitute a valid, enforceable
designation of a rate of interest or method of determining same, the
indebtedness hereby evidenced shall bear interest at the maximum effective
contract rate which may be charged by the Lender under applicable law from time
to time in effect.

         This Note is non-negotiable.

         Notwithstanding anything to the contrary, the payments required
pursuant to this Note are subject to a right of offset, setoff, and recoupment
as a result of any indemnification required pursuant to the provisions of that
certain Purchase and Sale Agreement by and between Lender and Maker dated as of
April 12, 1996.

         Subject to the Lender's option to require any payment of principal and
interest to be made in the form of Shares as hereinabove provided, all
installments of interest, and the principal hereof, are payable by Maker's


<PAGE>   28


corporate check at ______________________________ or at such other place as the
holder may designate in writing, in lawful money of the United States of
America, which shall be legal tender in payment of all debts and dues, public
and private, at the time of payment.

         If the Maker shall fail to make payment of any installment of
principal and interest, as above provided, and such failure shall continue
unremedied for a period of thirty (30) days following written notice thereof,
or upon the termination of the Service Agreement on account of a Response Event
of Default (as defined in the Service Agreement) or upon the dissolution of the
Maker or any endorser, and (if there is a cure period applicable thereto) such
default is not cured within such applicable cure period, then and in any such
event, the entire unpaid principal balance of the indebtedness evidenced
hereby, together with all interest then accrued, shall, at the absolute option
of the holder hereof, at once become due and payable, without demand or notice,
the same being hereby expressly waived.

         If this Note is placed in the hands of an attorney for collection, by
suit or otherwise, the Maker shall pay on demand all costs of collection and
litigation (including court costs), together with a reasonable attorney's fee
if Lender is successful in the litigation.

         It is the intention of the Lender and the Maker to comply strictly
with applicable usury laws; and, accordingly, in no event and upon no
contingency shall the holder hereof ever be entitled to receive, collect, or
apply as interest any interest, fees, charges or other payments equivalent to
interest, in excess of the maximum effective contract rate which the Lender may
lawfully charge under applicable statutes and laws from time to time in effect;
and in the event that the holder hereof ever receives, collects, or applies as
interest any such excess, such amount which, but for this provision, would be
excessive interest, shall be applied to the reduction of the principal amount
of the indebtedness hereby evidenced; and if the principal amount of the
indebtedness evidenced hereby, all lawful interest thereon and all lawful fees
and charges in connection therewith, are paid in full, any remaining excess
shall forthwith be paid to the Maker, or other party lawfully entitled thereto.
All interest paid or agreed to be paid by the Maker shall, to the maximum
extent permitted under applicable law, be amortized, prorated, allocated and
spread throughout the full period until payment in full of the principal so
that the interest hereon for such full period shall not exceed the maximum
amount permitted by applicable law. Any provision hereof, or of any other
agreement between the holder hereof and the Maker, that operates to bind,
obligate, or compel the Maker to pay interest in excess of such maximum
effective contract rate shall be construed to require the payment of the
maximum rate only. The provisions of this paragraph shall be given precedence
over any other provision contained herein or in any other agreement between the
holder hereof and the Maker that is in conflict with the provisions of this
paragraph.

         This Note shall be governed and construed according to the statutes
and laws of the State of Tennessee from time to time in effect.


                                        RESPONSE ONCOLOGY, INC.

                                        By:
                                           ------------------------------------
                                        Title:
                                              ---------------------------------


<PAGE>   29


                                Exhibit 2(b)(ii)
                                       to
                          Purchase and Sale Agreement

                                                          CERTIFICATE NO. W-____

THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR ANY
STATE SECURITIES LAW, HAS BEEN ACQUIRED FOR INVESTMENT ONLY AND MAY NOT BE
SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF
UNLESS IT HAS BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 AND ANY
APPLICABLE STATE SECURITIES LAW, OR THE PROPOSED TRANSFER IS EXEMPT FROM THE
REGISTRATION REQUIREMENTS OF THE SECURITIES ACT OF 1933 AND ANY APPLICABLE
STATE SECURITIES LAW.



- --------------------------------------------------------------------------------

                        WARRANT TO PURCHASE COMMON STOCK

                                       OF

                            RESPONSE ONCOLOGY, INC.

- --------------------------------------------------------------------------------


         This Warrant is granted as of April 12, 1996 by Response Oncology,
Inc., a Tennessee corporation (the "Issuer"), which certifies that, for value
received, the registered holder hereof, or its registered assigns (the
registered holder or assigns are referred to herein as the "Holder"), is
entitled to purchase from the Issuer, at any time and from time to time during
the Exercise Period (as hereinafter defined) at the Exercise Price (as
hereinafter defined) per share (as adjusted as herein provided), 20,000 shares
of common stock, $.01 par value per share (the "Common Stock") of Response
Oncology, Inc. (such number of shares of Common Stock purchasable upon the
exercise of this Warrant to Purchase Common Stock, as adjusted from time to
time pursuant to the provisions hereinafter set forth, are referred to in this
Warrant as the "Warrant Shares").  This Warrant has been issued in connection
with and as partial consideration for the acquisition (the "Purchase") by the
Issuer of 100% of the Partnership Interests in Knoxville Hematology Oncology
Associates (the "Partnership") from the partners of the Partnership (the
"Partners") pursuant to that certain Purchase and Sale Agreement dated as of
April 12, 1996 among the Issuer and the Partners of the Partnership.


        VOID AFTER 5:00 P.M. MEMPHIS, TENNESSEE TIME, ON APRIL 11, 2001,
           SUBJECT TO EARLIER TERMINATION AS HEREINAFTER SET FORTH


<PAGE>   30

         This Warrant is subject to the following terms and conditions:

         1. Exercise Period. The period in which the Holder shall have the
right to exercise this Warrant (the "Exercise Period") shall commence on the
date that is one (1) year after the date hereof and shall terminate on (the
"Termination Date") the earlier of (i) April 11, 2001, (ii) the occurrence of
any merger, voluntary dissolution or other event pursuant to which the
existence of the Issuer shall terminate, or (iii) upon the termination of that
certain Service Agreement (the "Service Agreement") between the Issuer and
Knoxville Hematology-Oncology Associates, P.L.L.C. (the "Provider") in
accordance with its terms after occurrence of a Provider Event of Default (as
defined in the Service Agreement).

         2. Exercise Price. The Exercise Price shall be equal to $11.75 per
share.  The Exercise Price is subject to adjustment as provided in Section 5
below.

         3. Termination of Warrants. The Warrants shall terminate on the
Termination Date and shall not be exercisable thereafter.

         4. Exercise of Warrants. (a) The Warrants may be exercised in whole or
in part, at any time and from time to time, during the Exercise Period by
surrendering this Warrant, with the purchase form provided for herein duly
executed by the Holder or by the Holder's duly authorized attorney-in-fact, at
the principal office of the Issuer or at such other office in the United States
as the Issuer may designate by notice in writing to the Holder (the "Issuer's
Office") accompanied by payment of the Exercise Price in full, (i) in cash or
by certified or cashier's check, payable to the order of the Issuer, (ii) by
wire transfer in accordance with instructions provided by the Issuer, or (iii)
by the Holder's delivery, in transferable form, of certificates representing
the number of shares of the Issuer's Common Stock which, when valued at the
last sale price on the Nasdaq Stock Market's National Market on the dated date
of the purchase form, would be sufficient to satisfy the Exercise Price in
full. If fewer than all of the Warrants are exercised, the Issuer shall, upon
each exercise prior to the expiration of the Exercise Period, execute and
deliver to the Holder an amendment to this Warrant (dated the date hereof)
evidencing the balance of the Warrants that remain exercisable.

         (b) On the date of exercise of the Warrant, the Holder exercising the
same shall be deemed to have become the holder of record for all purposes of
the Warrant Shares to which the exercise relates.

         (c) As soon as practicable, but not later than ten (10) days after the
exercise of all or part of the Warrants, the Issuer shall, at the Issuer's
expense (including the payment of any applicable issue taxes and the cost of
any opinion of counsel required by the Issuer or its transfer agent), cause to
be issued in the name of and delivered to the Holder a certificate or
certificates evidencing the number of fully paid and nonassessable Warrant
Shares to which the Holder shall be entitled upon such exercise.

         (d) The Warrant Shares issued upon exercise of this Warrant will not
be registered under the Securities Act of 1933, as amended (the "Act") or the
securities laws of any state in reliance on exemptions from the registration
requirements of the Act and such laws. Accordingly, the Warrant Shares may be
sold or otherwise transferred only upon (i) registration under the Act and
qualification under applicable state securities laws, (ii) compliance with Rule
144 under the Act, or (iii) the Issuer's receipt of an opinion, at the Holder's
expense, from counsel reasonably acceptable to the Issuer to the effect that
any such sale or transfer will not violate the Act or any state law. The Issuer
will cause an appropriate legend to be placed on certificates representing the
Warrant Shares to the foregoing effect.

         5. Adjustments of Exercise Price, Number and Character of Warrant
Shares, and Number of Warrants. The Exercise Price, the number and kind of
securities purchasable upon the exercise of each Warrant, and the number of
Warrants outstanding shall be subject to adjustment from time to time upon the
happening of the events enumerated in this Section 5.

<PAGE>   31

         (a) In case the Issuer shall at any time on or after the date
hereof (i) pay a dividend in shares of Common Stock or other securities of the
Issuer or make a distribution in shares of Common Stock or such other
securities to holders of all its outstanding shares of Common Stock, (ii)
subdivide or reclassify the outstanding shares of Common Stock into a greater
number of shares, (iii) combine the outstanding shares of Common Stock into a
smaller number of shares of Common Stock, or (iv) issue by reclassification of
its shares of Common Stock other securities of the Issuer (including any such
reclassification in connection with a consolidation or merger in which the
Issuer is the continuing corporation), then the number and kind of Warrant
Shares purchasable upon exercise of each Warrant outstanding immediately prior
thereto shall be adjusted so that the Holder shall be entitled to receive the
kind and number of shares of Common Stock or other securities of the Issuer
which the Holder would have owned or have been entitled to receive after the
happening of any of the events described above had such Warrant been exercised
in full immediately prior to the earlier of the happening of such event or any
record date in respect thereof. In the event of any adjustment of the total
number of shares of Common Stock purchasable upon the exercise of the then
outstanding Warrants pursuant to this Section 5(a), the Exercise Price shall be
adjusted to be the amount resulting from dividing the number of shares of
Common Stock (including fractional shares of Common Stock) covered by such
Warrant immediately after such adjustment into the total amount payable upon
exercise of such Warrant in full immediately prior to such adjustment. An
adjustment made pursuant to this Section 5(a) shall become effective
immediately after the effective date of such event retroactive to the record
date for any such event. Such adjustment shall be made successively whenever
any event listed above shall occur.

         (b) In case the Issuer shall at any time after the date hereof fix a
record date for the issuance of rights, options, or warrants to all holders of
its outstanding shares of Common Stock, entitling them (for a period expiring
within forty-five (45) days after such record date) to subscribe for or
purchase shares of Common Stock (or securities exchangeable for or convertible
into shares of Common Stock) at a price per common share (or having an exchange
or conversion price per common share, with respect to a security exchangeable
for or convertible into shares of Common Stock) which is lower than the
Exercise Price per common share on such record date, then the Exercise Price
shall be adjusted by multiplying the Exercise Price in effect immediately prior
to such record date by a fraction, of which the numerator shall be the number
of shares of Common Stock outstanding on such record date plus the number of
shares of Common Stock which the aggregate offering price of the total number
of shares of Common Stock so to be offered (or the aggregate initial exchange
or conversion price of the exchangeable or convertible securities so to be
offered) would purchase at such current Exercise Price and of which the
denominator shall be the number of shares of Common Stock outstanding on such
record date plus the number of additional shares of Common Stock to be offered
for subscription or purchase (or into which the exchangeable or convertible
securities so to be offered are initially exchangeable or convertible). Such
adjustment shall become effective at the close of business on such record date;
however, to the extent that shares of Common Stock (or securities exchangeable
for or convertible into shares of Common Stock) are not delivered after the
expiration of such rights, options, or warrants, the Exercise Price shall be
readjusted (but only with respect to Warrants exercised after such expiration)
to the Exercise Price which would then be in effect had the adjustments made
upon the issuance of such rights, options, or warrants been made upon the basis
of delivery of only the number of shares of Common Stock (or securities
exchangeable for or convertible into shares of Common Stock) actually issued.
In case any subscription price may be paid in a consideration part or all of
which shall be in a form other than cash, the value of such consideration shall
be as determined in good faith by the Board of Directors of the Issuer and
shall be described in a statement mailed to the Holder. Shares of Common Stock
owned by or held for the account of the Issuer shall not be deemed outstanding
for the purpose of any such computation.

         (c) In case the Issuer shall at any time after the date hereof
distribute to all holders of its shares of Common Stock (including any such
distribution made in connection with a consolidation or merger in which the
Issuer is the surviving corporation) evidences of its indebtedness or assets
(excluding cash dividends and distributions payable out of consolidated net
income or earned surplus in accordance with applicable law and dividends or
distributions payable in shares of stock described in Section 5(a) above) or
rights, options, or warrants or exchangeable or convertible securities
containing the right to subscribe for or purchase shares of Common Stock (or
securities exchangeable for or convertible into shares of Common Stock)
(excluding those expiring within


<PAGE>   32

forty-five (45) days after the record date referred to in Section 5(b) above),
then the Exercise Price shall be adjusted by multiplying the Exercise Price in
effect immediately prior to the record date for such distribution by a
fraction, of which the numerator shall be the fair market value of the shares
of Common Stock on such day, as determined in good faith by the Board of
Directors of the Issuer whose determination shall be conclusive, and described
in a notice to the Holder of the portion of the evidences of indebtedness or
assets so to be distributed or of such rights, options or warrants applicable
to one common share and of which the denominator shall be such fair market
value per common share.  Such adjustment shall be made whenever any such
distribution is made, and shall become effective on the date of distribution
retroactive to the record date for such transaction.

         (d) For the purpose of this Warrant, the fair market value per share
of Common Stock shall be determined by reference to the latest independent bid
for the Common Stock as set forth in the National Market of The Nasdaq Stock
Market or, if the Common Stock shall be traded on any national or regional
securities exchange, the latest bid price for the Common Stock, or, if none of
the foregoing apply, as determined in good faith by the Board of Directors of
the Issuer.

         (e) No adjustment in the Exercise Price or the number of Warrant
Shares purchasable shall be required unless such adjustment would require an
increase or decrease of at least ten percent (10%) in the Exercise Price or the
number of Warrant Shares purchasable; provided, however, that any adjustments
which by reason of this Section 5(e) are not required to be made (i) shall be
carried forward and taken into account in any subsequent adjustment or (ii) if
no subsequent adjustment occurs, shall be made immediately prior to exercise of
this Warrant. All calculations under this Section 5 shall be made to the
nearest cent or to the nearest one-hundredth of a share, as the case may be.

         (f) Unless the Issuer shall have exercised its election as provided in
Section 5(g), upon each adjustment of the Exercise Price as a result of the
calculations made in Sections 5(b) or (c), each Warrant outstanding prior to
the making of the adjustment in the Exercise Price shall thereafter evidence
the right to purchase, at the adjusted Exercise Price, that number of shares of
Common Stock (calculated to the nearest hundredth) obtained by (i) multiplying
the number of shares of Common Stock purchasable upon exercise of a Warrant
prior to adjustment of the number of shares of Common Stock by the Exercise
Price in effect prior to adjustment of the Exercise Price and (ii) dividing the
product so obtained by the Exercise Price in effect after such adjustment of
the Exercise Price.

         (g) The Issuer may elect on or after the date of any adjustment of the
Exercise Price to adjust the number of Warrants, in substitution for any
adjustment in the number of Warrant Shares purchasable upon the exercise of
Warrants as provided in Sections 5(a) and (f). Each of the Warrants outstanding
after such adjustment of the number of Warrants shall be exercisable for one
share of Common Stock. Each Warrant held of record prior to such adjustment of
the number of Warrants shall become that number of Warrants (calculated to the
nearest hundredth) obtained by dividing the Exercise Price in effect prior to
adjustment of the Exercise Price by the Exercise Price in effect after
adjustment of the Exercise Price. The Issuer shall send to each Holder a notice
of its election to adjust the number of Warrants, indicating the record date
for the adjustment, and if known at the time, the amount of the adjustment to
be made. This record date may be the date on which the Exercise Price is
adjusted or any day thereafter, but shall be at least ten (10) days after the
date such announcement is sent to the Holders. Upon each adjustment of the
number of Warrants pursuant to this Section 5(g) the Issuer shall, as promptly
as practicable, cause to be distributed to holders of record of Warrants on
such record date new certificate(s) evidencing the additional Warrants to which
such holders shall be entitled as a result of such adjustment, or, at the
option of the Issuer, shall cause to be distributed to such holders of record
in substitution and replacement for the certificates held by such holders prior
to the date of adjustments, and upon surrender thereof if required by the
Issuer, new certificates evidencing all the Warrants to which such holders
shall be entitled after such adjustment.

         (h) In case of any capital reorganization of the Issuer, or of any
reclassification of the shares of Common Stock [other than a reclassification,
subdivision or combination of shares of Common Stock referred to in Section
5(a)], or in case of the consolidation of the Issuer with, or the merger of the

<PAGE>   33

Issuer with, or merger of the Issuer into, any other corporation, limited
partnership, limited liability company or other business entity (other than a
reclassification of the shares of Common Stock referred to in Section 5(a) or a
consolidation or merger which does not result in any reclassification or change
of the outstanding shares of Common Stock) or of the sale of the properties and
assets of the Issuer as, or substantially as, an entirety to any other
corporation or entity, each Warrant shall after such capital reorganization,
reclassification of shares of Common Stock, consolidation, merger, or sale be
exercisable, upon the terms and conditions specified in this Warrant, for the
kind, amount and number of shares or other securities, assets, or cash to which
a holder of the number of shares of Common Stock purchasable (at the time of
such capital reorganization, reclassification of shares of Common Stock,
consolidation, merger or sale) upon exercise of such Warrant would have been
entitled to receive upon such capital reorganization, reclassification of
shares of Common Stock, consolidation, merger, or sale; and in any such case,
if necessary, the provisions set forth in this Section 5 with respect to the
rights and interests thereafter of the holders of the Warrants shall be
appropriately adjusted so as to be applicable, as nearly equivalent as
possible, to any shares or other securities, assets, or cash thereafter
deliverable on the exercise of the Warrants. The subdivision or combination of
shares of Common Stock at any time outstanding into a greater or lesser number
of shares shall not be deemed to be a reclassification of the shares of Common
Stock for purposes of this Section 5(h).

         (i) In the event that at any time, as a result of an adjustment made
pursuant to this Section 5, the holders of an Warrant or Warrants shall become
entitled to purchase any shares or securities of the Issuer other than the
shares of Common Stock, thereafter the number of such other shares or
securities so purchasable upon exercise of each Warrant and the exercise price
for such shares or securities shall be subject to adjustment from time to time
in a manner and on terms as nearly equivalent as possible to the provisions
with respect to the shares of Common Stock contained in Sections 5(a) through
(h), inclusive.

         (j) In any case in which this Section 5 shall require that an
adjustment in the Exercise Price be made effective as of a record date for a
specified event, the Issuer may elect to defer until the occurrence of such
event issuing to the holder of any Warrant exercised after such record date the
shares of Common Stock, if any, issuable upon such exercise over and above the
Warrant Shares, if any, issuable upon such exercise on the basis of the
Exercise Price in effect prior to such adjustment; provided, however, that the
Issuer shall deliver as soon as practicable to such holder a due bill or other
appropriate instrument provided by the Issuer evidencing such holder's right to
receive such additional shares of Common Stock upon the occurrence of the event
requiring such adjustment.

         (k) Notwithstanding anything herein to the contrary, no adjustment
shall be required under this Section 5 in the event the Issuer (i) issues
options to purchase Common Stock or other securities to officers, directors,
employees or agents pursuant to an incentive or non-qualified stock option
plan, or (ii) issues shares of Common Stock or other securities pursuant to an
offering for cash or other consideration (including the assets or capital stock
or securities of any other corporation or other business entity), or pursuant
to a plan of merger whereby the Issuer is the surviving participant in the
merger, other than an issuance of rights, options or warrants exercisable for
shares of Common Stock (or securities exchangeable for or convertible into
shares of Common Stock) to all holders of its outstanding shares of Common
Stock.

         6. Definition of shares of Common Stock. The shares of Common Stock
issuable upon exercise of the Warrants shall be the shares of Common Stock as
constituted on the date hereof except as otherwise provided in Section 5.

         7. Notice of Number of Warrant Shares, Adjustment or Termination.
Within thirty (30) days of the occurrence of an event which results in an
adjustment in the number of Warrants, the number of Warrant Shares purchasable
upon the exercise of Warrants and/or the Exercise Price or the termination of
the Warrants shall have occurred as provided herein, the Issuer shall
forthwith:

         (a) prepare and hold for inspection at the Issuer's principal place of
business, 1775 Moriah Woods Blvd., Memphis, Tennessee 38117, or such subsequent
principal place of business (the "Issuer's Office"), a statement,

<PAGE>   34

signed by the Chief Financial Officer of the Issuer, stating either (i) the
number of Warrants or Warrant Shares, (ii) the adjusted number of Warrants or
Warrant Shares purchasable upon the exercise of Warrants and/or Exercise Price
determined as herein provided, such statement to show in detail the facts
requiring such adjustment or (iii) the termination of the Warrants, and

         (b) give notice embodying such statement to each Holder as provided in
Section 13. Where appropriate, such notice may be given in advance and may be
included as part of a notice required to be mailed pursuant to Section 8.

         8. Notices of Record Date, etc. In the event the Issuer shall propose
to take any action of the type requiring an adjustment of the Exercise Price or
the number or character of the Warrant Shares or Warrants pursuant to Section 5
or a dissolution, liquidation or winding up of the Issuer (other than in
connection with a consolidation, merger, or sale of all or substantially all of
its property, assets, and business as an entirety) shall be proposed, the
Issuer shall give notice to each Holder as provided in Section 15, which notice
shall specify the record date, if any, with respect to any such action and the
date on which such action is to take place. Such notice shall also set forth
such facts with respect thereto as shall be reasonably necessary to indicate
the effect of such action (to the extent such effect may be known at the date
of such notice) on the Exercise Price and the number, kind or class of shares
or other securities or property which shall be deliverable or purchasable upon
the occurrence of such action or deliverable upon the exercise of the Warrants.
In the case of any action which will require the fixing of a record date,
unless otherwise provided in this Warrant, such notice shall be given at least
twenty (20) days prior to the date so fixed, and in case of all other action,
such notice shall be given at least thirty (30) days prior to the taking of
such proposed action.

         9. Replacement of Securities. If this Warrant shall be lost, stolen,
mutilated or destroyed, the Issuer shall, on such terms as to indemnity or
otherwise as the Issuer may in its discretion reasonably impose, issue a new
certificate of like tenor or date representing in the aggregate the right to
subscribe for and purchase the number of shares of Common Stock which may be
subscribed for and purchased hereunder. Any such new certificate shall
constitute an original contractual obligation of the Issuer, whether or not the
allegedly lost, stolen, mutilated or destroyed Warrant shall be at any time
enforceable by anyone.

         10. Recordkeeping. This Warrant, as well as all other warrant
certificates representing Warrants of like tenor issued in connection with the
Purchase and Sale Agreement shall be numbered beginning with the alphabetic
prefix "KN" and shall be registered in a register (the "Warrant Register")
maintained at the Issuer's Office as they are issued. The Warrant Register
shall list the name, address and Social Security or other Federal
Identification Number, if any, of all Holders. Upon notice duly given by the
Holder, the Issuer shall be entitled to recognize the Holder as set forth in
the Warrant Register as the nominee for the beneficial owners of the Warrants
as set forth in such notice or subsequent notices with respect to such
beneficial ownership recognize for all purposes and shall not be bound to
recognize any equitable or other claim to or interest in such Warrant on the
part of any other person, and shall not be liable for any registration of
transfer of Warrants that are registered or to be registered in the name of a
fiduciary or the nominee of a fiduciary unless made with the actual knowledge
that a fiduciary or nominee is committing a breach of trust in requesting such
registration of transfer, or with such knowledge of such facts that its
participation therein amounts to bad faith.

         11. Transfer. This Warrant shall not be transferable and may not be
the subject of a sale, assignment, pledge or other conveyance without the
Issuer's advance consent, which the Issuer may withhold in its absolute
discretion. The Warrant shall be transferable only on the Warrant Register upon
delivery of such Warrants, with the assignment form provided for herein duly
executed by the Holder or by the Holder's duly authorized attorney-in-fact.
Upon any registration of transfer, the Issuer shall execute and deliver a new
Warrant certificate to the person entitled thereto.

<PAGE>   35

         The Warrants have not been registered under the Secuities Act of 1933
or any state securities law, and, accordingly, may not be sold, transferred, 
assigned, pledged, hypothecated or otherwise disposed of unless they have been
registered under the Securities Act of 1933 and any applicable state securities
law or, in the opinion of counsel reasonably satisfactory to the Issuer, whose
fees and expenses in connection with such opinion will be borne by the Holder,
the proposed transfer is exempt from the registration requirements of the 
Securities Act of 1933 and any applicable state securities law.

         12. Exchange of Warrant Certificates. This Warrant may be exchanged
for another certificate or certificates entitling the Holder thereof to
purchase a like aggregate number of Warrant Shares as this Warrant entitles
such Holder to purchase. A Holder desiring to so exchange this Warrant shall
make such request in writing delivered to the Issuer, and shall surrender this
Warrant therewith. Thereupon, the Issuer shall execute and deliver to the
person entitled thereto a new certificate or certificates, as the case may be,
as so requested.

         13. Piggyback Registration.

                 (a)      Notice of Piggyback Registration and Inclusion of 
Warrant Shares.

                 If, after the Holder's exercise of the Warrants pursuant to
Section 4 hereof, at any time or from time to time the Issuer shall elect to
file a registration statement ("Registration Statement") on Form S-1, S-2 or
S-3 (or any successor form thereto) under the Act with respect to any of its
securities, either for its own account or the account of a security holder or
holders, other than a registration of a public offering of Common Stock
commenced within one (1) year of the date hereof or a registration relating
solely to employee benefit plans (excluding the foregoing events, a
"Registration"), the Issuer will: (i) promptly give each Holder written notice
thereof (which shall include a list of the jurisdictions in which the Issuer
intends to attempt to qualify such securities under the applicable Blue Sky or
other state securities laws) and (ii) include in such Registration (and any
related registration and/or qualification under Blue Sky laws or other
compliance), and in any underwriting involved therein, all or such portion of
the Warrant Shares specified in a written request delivered to the Issuer by
any Holder within 30 days after delivery of such written notice from the
Issuer.

                 (b)      Underwriting in Piggyback Registration.

                          (i)     NOTICE OF UNDERWRITING IN PIGGYBACK 
REGISTRATION.

                          If the Registration of which the Issuer gives notice
is for a Registered public offering involving an underwriting, the Issuer shall
so advise the Holders as a part of the written notice given pursuant to Section
13(a). In such event, the right of any Holder to Registration shall be
conditioned upon such underwriting and the inclusion of such Holder's Warrant
Shares in such underwriting to the extent provided in this Section 13. All
Holders proposing to distribute their securities through such underwriting
shall (together with the Issuer and any other holders distributing their
securities through such underwriting) enter into an underwriting agreement in
customary form with the representative of the Underwriter ("Underwriter's
Representative") for such offering. The Holders shall have no right to
participate in the selection of underwriters for an offering pursuant to this
Section.

                          (ii)    MARKETING LIMITATION IN PIGGYBACK 
REGISTRATION.

                          In the event the Underwriter's Representative advises
the Holders seeking Registration of Warrant Shares pursuant to Section 13 in
writing that market factors (including, without limitation, the aggregate
number of shares of Common Stock requested to be included in such Registration,
the general condition of the market, and the status of the persons proposing to
sell securities pursuant to the Registration) require a limitation of the
number of shares to be underwritten, the Underwriter's Representative (subject
to the allocation priority set forth in Section 13(a)(iii) may limit (or reduce
to zero) the number of Warrant Shares to be included in

<PAGE>   36

such Registration and underwriting; provided however, that any Warrant Shares
so excluded shall retain any and all Registration rights set forth in Section
13 hereof.

                          (iii)   ALLOCATION OF WARRANT SHARES IN PIGGYBACK
REGISTRATION.

                          In the event that the Underwriter's Representative
limits the number of shares to be included in a Registration pursuant to
Section 13(a)(ii), the number of shares to be included in such Registration
shall be allocated in the following manner: Common Stock held by persons who
are not contractually entitled to include shares in such Registration shall be
excluded from such Registration and underwriting to the extent required by such
limitation.  If a limitation of the number of shares is still required after
such exclusion, the number of shares of Common Stock that may be included in
the Registration and underwriting by all selling shareholders (including the
Holders and all other persons contractually entitled to such registration)
shall be allocated among Holders and other holders of securities other than
Warrant Shares requesting and contractually entitled to include shares in such
Registration, in proportion, as nearly as practicable, to the respective
amounts of securities (including Warrant Shares) which such Holders and such
other holders would otherwise be entitled to include in such Registration. No
Warrant Shares or other securities excluded from the underwriting by reason of
this Section 13(a)(iii) shall be included in the Registration Statement.

                          (iv)    WITHDRAWAL IN PIGGYBACK REGISTRATION.

                          If any Holder disapproves of the terms of any such
underwriting, he may elect to withdraw therefrom by written notice to the
Issuer and the underwriter delivered at least seven days prior to the effective
date of the Registration Statement. Any Warrant Shares or other securities
excluded or withdrawn from such underwriting shall be withdrawn from such
Registration.

                 (c) Blue Sky in Piggyback Registration.

                 In the event of any Registration of Warrant Shares pursuant to
Section 13, the Issuer will use its best efforts to register and/or qualify the
securities covered by the Registration Statement under such other securities or
Blue Sky laws of such jurisdictions as shall be reasonably appropriate for the
distribution of such securities; provided, however, that notwithstanding
anything in this Agreement to the contrary, in the event any jurisdiction in
which the securities shall be qualified imposes a non-waivable requirement that
expenses incurred in connection with the qualification of the securities be
borne by selling shareholders, the Holders shall pay their pro rata share of
such expenses.

         14. Demand Registration.

                 (a)      Request for Registration.

                 Subject to exceptions as hereinafter provided, after the first
anniversary of the Closing Date, the Holders which have exercised Warrants
pursuant to Section 4 hereof (the "Unregistered Shares"), may annually make a
single request (a "Demand") in writing within 30 days of the anniversary date
that the Issuer file and effect a registration statement with the Commission in
respect of all, but not less than all, shares of Unregistered Shares held by
the Holders. Upon receipt of a Demand, the Issuer shall as soon as practicable
cause a Registration Statement to be filed with the Commission, which
Registration Statement shall, if not an Underwritten Offering pursuant to
Section 13 above, contain all appropriate undertakings necessary to comply with
Rule 415 under the 1933 Act pertaining to "shelf registration", and the Issuer
shall use its best efforts to effect such Registration (including the execution
of an undertaking to file post effective amendments and any related
registration or qualification under Blue Sky Laws or other compliance with the
Securities Act) as may be so requested and as would permit or facilitate the
sale and distribution of the Unregistered Shares.

                 (b) Registration of Other Securities in Demand Registration.

<PAGE>   37

                 Any Registration Statement filed pursuant to the request of
the Holders under this Section 14 may, subject to the provisions of Section
14(d), include securities of the Issuer other than the Unregistered shares.

                 (c) Blue Sky in Demand Registration.

                 In the event of any Registration of Warrant Shares pursuant to
Section 14, the Issuer will use its best efforts to register and/or qualify the
securities covered by the Registration Statement under such other securities or
Blue Sky laws of such jurisdictions as shall be reasonably appropriate for the
distribution of such securities; provided, however, that notwithstanding
anything in this Agreement to the contrary, in the event any jurisdiction in
which the securities shall be qualified imposes a non-waivable requirement that
expenses incurred in connection with the qualification of the securities be
borne by selling shareholders, the Holders shall pay their pro rata share of
such expenses.

                 (d)      Underwritten Demand Registration.

                 The Holders making a Demand shall be entitled to engage an
underwriter reasonably acceptable to the Issuer to offer and sell in a public
offering the Unregistered Shares included in any Registration Statement filed
pursuant to Section 14(a) above. In such event, the Issuer and each
participating Holder shall enter into an underwriting agreement in customary
form with the representative of the underwriter ("Underwriter's
Representative") for such offering. Whether or not an underwriting agreement is
entered into, the Issuer shall:

                          (i)     make such representation and warranties to
the Holders participating in such registration and the underwriters, if any, in
form, substance and scope as are customarily made by issuers to underwriters in
comparable underwritten offerings;

                          (ii)    obtain opinions of counsel to the Issuer and
updates thereof (which counsel and opinions (if form, scope and substance)
shall be reasonably satisfactory to the Underwriter's Representative, if any,
and the Holders of a majority in number of the Unregistered Shares being sold)
addressed to such Holders and underwriters, if any, covering the matters
customarily covered in opinions requested in underwritten offerings and such
other matters as may be reasonably requested by such Holders and the
underwriters, if any;

                          (iii)   obtain comfort letters and updates thereof
from the Issuer's independent certified public accountants addressed to the
selling Holders and the underwriters, if any, such letters to be in customary
form and covering matters of the type (including the "circling" of numbers in
the prospectus included in the Registration Statement, with appropriate legends
explaining the procedures performed with respect to "circled" numbers)
customarily covered in comfort letters by independent certified public
accountants in connection with underwritten offerings, on such date or dates as
may be reasonably requested by the Underwriters' Representative and the Holders
of a majority of the Unregistered Shares being sold; and

                          (iv)    prepare and file with the Commission such
amendments and supplements to the Registration Statement and the prospectus
used in connection therewith as may be necessary to keep the Registration
Statement effective for the period of the distribution contemplated thereby and
to comply with the provisions of the Securities Act with respect to the
disposition of all Warrant Shares covered by the Registration Statement in
accordance with the selling Holders' intended method of disposition set forth
in the Registration Statement for such period;

                          (v)     immediately notify each selling Holder under
the Registration Statement and each underwriter, at any time when a prospectus
relating thereto is required to be delivered under the Securities Act, of the
happening of any event as a result of which the prospectus contained in the
Registration Statement, as then in effect, includes any untrue statement of a
material fact or omits to state any material fact required to be

<PAGE>   38

stated therein or necessary to make the statements therein not misleading in
light of the circumstances then existing;

                          (vi)    make available for inspection by each selling
Holder, any underwriter participating in any distribution pursuant to the
Registration Statement, and any attorney, accountant or other agent retained by
such Holder or underwriter, all financial and other records, pertinent
corporate documents and properties of the Company, and cause the Company's
officers, directors and employees to supply all information reasonably
requested by any such Holder, underwriter, attorney, accountant or agent in
connection with the Registration Statement;

                          (vii)   use its best efforts to take actions
necessary or advisable to effect such registration in the manner contemplated
by this Agreement; and

                          (viii)  deliver such documents and certificates as
may be reasonably requested by the Holders of a majority of the Unregistered
Shares being sold and the Underwriters' Representative, if any, to evidence
compliance with any customary conditions contained in the underwriting
agreement.

         In connection with such Underwritten Offering, the Issuer shall (i)
make provide to a single counsel for the Holders whose Unregistered Shares are
included in such Underwritten Offering, for such counsel's review and comment,
drafts of the Registration Statement; (ii) provide such counsel with a
reasonable number of executed copies of the Registration Statement and all
amendments thereto, as filed, as well as a reasonable number of preliminary
prospectuses used by the underwriters in such Underwritten Offering; (iii) give
prompt notice to such counsel of the effectiveness of such registration
statement and of any stop order issued by the Commission or proceeding, or
threat of such a proceeding, by the Commission for the purpose of issuing a
stop order or otherwise suspending the effectiveness of any Registration
Statement; (iv) provide to the Holders a reasonable number of final
prospectuses delivered to purchasers under the Securities Act; and (v) for such
period for which prospectuses are required to be delivered by dealers, provide
such dealers with an adequate number of final prospectuses in order to permit
the dealers to comply with their obligations under the Securities Act. In all
other regards, the Issuer agrees to comply with the requirements of the
Securities Act in connection with any Underwritten Offering.

                 (e)      Right of Redemption. The Issuer shall have the right
to redeem the Unregistered Shares at a price equal to the average of the price
as quoted for the Common Stock as set forth in the National Market of The
Nasdaq Stock Market or, if the Common Stock shall be traded on any national or
regional securities exchange, the latest bid price for the Common Stock, for
the prior ten (10) trading days prior to the date the Demand is received;
provided, however, that in the event the Issuer shall elect to exercise such
redemption right, the Holder shall have the right, exercisable in writing for a
period of three (3) days following delivery by the Issuer of its notice of
intent to redeem Shares, to withdraw Holder's Demand, in which event the
redemption notice shall, with no further action on the part of the Issuer, be
deemed revoked and the Holder shall retain the Unregistered Shares that were
the subject of the Demand.

         14A.    Expenses of Registration. All expenses incurred in connection
with any registration, qualification or compliance pursuant to Sections 13 or
14, including, without limitation, all registration, filing and qualification
fees (including blue sky fees and expenses), printing expenses (including,
without limitation, those associated with printing a quantity of preliminary
and final prospectuses for distribution), accounting fees, escrow fees, the
fees and disbursements of counsel for the Company with respect to such
registration, fees of any exchange or of the National Association of Securities
Dealers, Inc., transfer taxes, fees of transfer agents and registrars,
out-of-pocket expenses of any underwriter (to the extent required to be paid by
the Issuer or Holders), costs of insurance (if any) and expenses of any special
audits incidental to or required by such registration, shall be borne by the
Company; provided, however, that the following expenses shall be borne by the
Holders, pro rata, according to their securities so registered:


<PAGE>   39

                 a.       All fees and disbursements of counsel for the
                          Holders; and

                 b.       Underwriters' fees, discounts and commissions
                          relating to the Warrant Shares which are the subject
                          of or included for sale in the Registration
                          Statement.

         14B.    Indemnification.

                 a.       To the extent permitted by law, the Company shall
indemnify each Holder against all claims, losses, damages and liabilities (or
actions in respect thereof) arising out of or based on (i) any untrue statement
(or alleged untrue statement) of a material fact contained in any prospectus,
offering circular or other documents (including any related registration
statement, notification or the like) incident to any such registration,
qualification or compliance, or (ii) any omission (or alleged omission) to
state therein a material fact required to be stated therein or necessary to
make the statements therein not misleading, or (iii) any violation by the
Company of any rule or regulation promulgated under the Securities Act or any
state securities law applicable to the Company and relating to action or
inaction required of the Company in connection with any such registration,
qualification or compliance, and will reimburse each such person, each of its
officers and directors, and each person controlling such person, for any legal
and any other expenses reasonably incurred in connection with investigating or
defending any such claim, loss, damage, liability or action, provided that the
Company will not be liable in any such case to the extent that any such claim,
loss, damage or liability or action arises out of or is based on any untrue
statement or any omission based upon written information furnished to the
Company by an instrument duly executed by any such person and stated to be
specifically for use therein.

                 b.       To the extent permitted by law, each Holder shall, if
securities held by or issuable to such person are included in the securities as
to which such registration, qualification or compliance is being effected,
indemnify the Company, each of its directors and officers who sign such
registration statement, each underwriter, if any, of the Company's securities
covered by such registration statement, each person who controls the Company
within the meaning of the Securities Act and each other such Holder, each
officer and director and each person controlling each such underwriter, or
other Holder against all claims, losses, damages and liabilities (or actions in
respect thereof) arising out of or based on (i) any untrue statement (or
alleged untrue statement) of a material fact contained in any such registration
statement, prospectus, offering circular or other document, or (ii) any
omission (or alleged omission) to state therein a material fact required to be
stated therein or necessary to make the statements therein not misleading, and
will reimburse the Company, and such other Holders, such directors, officers,
persons or underwriters for any legal or any other expenses reasonably incurred
in connection with investigating or defending any such claim, loss, damage,
liability or action, in each case to the extent, but only to the extent, that
such untrue statement (or alleged untrue statement) or omission (or alleged
omission) is made in such registration statement, prospectus, offering circular
or other document in reliance upon and in conformity with written information
furnished to the Company by an instrument duly executed by such Holder and
stated to be specifically for use therein.

                 c.       Each party entitle to indemnification under this
Section 14B (the "Indemnified Party") shall give notice to the party required
to provide indemnification (the "Indemnifying Party") promptly after such
Indemnified Party has actual knowledge of any claim as to which indemnity may
be sought, and shall permit the Indemnifying Party to assume the defense of any
such claim or any litigation resulting therefrom, provided that counsel for the
Indemnifying Party, who shall conduct the defense of such claim or litigation,
shall be approved by the Indemnified Party (whose approval shall not be
unreasonably withheld), and the Indemnified Party may participate in such
defense at such party's expense, and provided further that the failure of any
Indemnified Party to give notice as provided herein within a reasonable amount
of time, if such failure is prejudicial to the Indemnifying Party's ability to
defend such action, shall relieve the Indemnifying Party of its obligations
under this Section 14B, but not of any obligation arising aprt from this
Section 14B. No Indemnifying Party, in the defense of any such claim or
litigation, shall, except with the consent of each Indemnified Party, consent
to entry of any judgment or enter into any settlement which does not include as
an unconditional term thereof the giving by the

<PAGE>   40

claimant or plaintiff to such Indemnified Party of a release from all liability
with respect to such claim or litigation. If any such Indemnified Party shall
have reasonably concluded that there may be one or more legal defenses
available to such Indemnified party which are different from or additional to
those available to the Indemnifying Party, or that such claim or litigation
involves or could have an effect upon matters beyond the scope of the indemnity
agreement provided in this Section 14B, the Indemnifying Party shall not have
the right to assume the defense of such action on behalf of such Indemnified
Party and such Indemnifying Party shall reimburse such indemnified Party and
any person controlling such Indemnified Party for that portion of the fees and
expenses of any counsel retained by the Indemnified Party which are reasonably
related to the matters covered by the indemnity agreement provided in this
Section 14B.

         15. Notices. All notices and other communications hereunder shall be
in writing and shall be deemed given when delivered in person, against written
receipt therefor, or two days after being sent, by registered or certified
mail, postage prepaid, return receipt requested, and, if to the Holder, at such
address as is shown on the Warrant Register or as may otherwise may have been
furnished to the Issuer in writing by the Holder and, if to the Issuer, at the
Issuer's Office.

         16. Miscellaneous. This Warrant and any term hereof may be changed,
waived, discharged or terminated only by an instrument in writing signed by the
party against which enforcement of such change, waiver, discharge or
termination is sought. This certificate is deemed to have been delivered in the
State of Tennessee and shall be construed and enforced in accordance with and
governed by the laws of such State. The headings in this Warrant to Purchase
Common Stock Certificate are for purposes of reference only, and shall not
limit or otherwise affect any of the terms hereof.

         17. Expiration. Unless as hereinafter provided, the right to exercise
these Warrants shall terminate upon the expiration of the Exercise Period.

         IN WITNESS WHEREOF

                                          RESPONSE ONCOLOGY, INC.


DATEED: April 12, 1996                 By:
                                          --------------------------------------
                                          Daryl Johnson, Chief Financial Officer


<PAGE>   41

                                PURCHASE FORM

                         TO: RESPONSE ONCOLOGY, INC.

                                                   Dated:_________________, 19__


         The undersigned hereby irrevocably elects to exercise the within
Warrants, to the extent of purchasing __________ shares of Common Stock, and
hereby makes payment of $______________ in payment of the actual Exercise Price
thereof.




                     INSTRUCTIONS FOR REGISTRATION OF STOCK


Name:
     --------------------------------------------------------------------------
                 (Please typewrite or print in block letters)


Address:
        -----------------------------------------------------------------------

Signature:
          ---------------------------------------------------------------------
                 (Signature must conform in all respects to the name of the
                 Holder as set forth on the face of this Warrant.)

<PAGE>   42


                               ASSIGNMENT FORM


         FOR VALUE RECEIVED, __________________________________ hereby sells,
assigns and transfers unto


Name: 
     --------------------------------------------------------------------------
         (Please typewrite or print in block letters)


Address:
        -----------------------------------------------------------------------

the right to purchase shares of Common Stock represented by this Warrant to the
extent of ___________________________________________ shares as to which such
right is exercisable and does hereby irrevocably constitute and appoint
_______________________________ Attorney-in-Fact, to transfer the same on the
books of the Issuer with full power of substitution in the premises.


Dated:________________, 19__


Signature
         ----------------------------------------------------------------------
                 (Signature must conform in all respects to the name of the
                 Holder as set forth on the face of this Warrant.)


<PAGE>   43


                                Exhibit 6(a)(x)
                                       to
                          Purchase and Sale Agreement

                            EMPLOYMENT AGREEMENT FOR
                           PROFESSIONAL EMPLOYEES OF
               KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C.

         THIS AGREEMENT is entered into as of April 12, 1996 (the "Effective
Date"), by and between KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C., a
Tennessee professional limited liability company ("Employer") and
________________________, an individual residing in the State of Tennessee,
("Employee").

                                 WITNESSETH:

         WHEREAS, Employer is a professional group practice engaged in the
practice of medicine in the State of Tennessee;

         WHEREAS, Employee is an individual duly licensed to practice as a
physician in the State of Tennessee;

         WHEREAS, Employer wishes to employ Employee on a full-time basis to
provide professional services on behalf of Employer; and

         WHEREAS, Employee wishes to be so employed;

         NOW, THEREFORE, in consideration of the foregoing premises and of the
mutual promises and covenants hereinafter set forth, the parties agree as
follows:

         1. SCOPE OF EMPLOYMENT. Employee agrees to devote substantially his
full time and energy to the practice of medicine, in the specialty of
oncology-hematology on behalf of Employer, and to practice medicine solely as
an employee of Employer, except as may be otherwise agreed to by Employer in
writing. Employee shall represent himself professionally only under such
business or clinic name as shall be approved or designated by Employer, and
shall practice at the office location designated by Employer. Employee
understands that the governing body of Employer has final authority and
responsibility for determining the fee schedule for professional services
rendered by employees of Employer.

         2. COMPENSATION FOR SERVICES. Employer shall compensate Employee for
all services rendered by Employee under this Agreement in accordance with
Schedule A hereto. Employee understands and agrees that any and all monies due
to or received by Employee on account of the rendering of patient care services
or otherwise in the professional practice of his or her profession from and
after the effective date of this Agreement, regardless of the time and place
such services


<PAGE>   44

are delivered, shall be the exclusive property of Employer. The compensation
paid to Employee under this Agreement shall constitute full compensation to
Employee for services rendered under this Agreement, and Employee shall not
seek additional compensation from any source for services rendered under this
Agreement.

          3. BILLING. (a) Except as otherwise provided by law, only Employer
shall be entitled to bill for or otherwise receive payment from the patient or
any third party for services provided by Employee under this Agreement.
Employee shall have no right to receive, nor shall Employee attempt to bill for
or collect, payment from the patient or any third party for services provided
by Employee under this Agreement, except in the name of and for the sole
benefit of Employer.

         (b) Employee shall cooperate with and assist Employer in the
preparation and documentation of claims for services rendered by Employee under
this Agreement. Employee agrees to cooperate and comply with the terms of
applicable utilization management and similar cost management protocols, and to
do all things necessary and appropriate to maximize reimbursement to Employer
for services rendered by Employee under this Agreement, to the extent
consistent with law and with the best clinical interests of the patient.

         4. WORKING FACILITIES. Employer shall assure that Employee has
appropriate office space, support staff, supplies, equipment, and such other
facilities and services as Employer deems necessary and appropriate to his or
her position and for the performance of Employee's duties.

         5. PROFESSIONAL RELATIONSHIPS. Employer and Employee each acknowledges
and agrees that the business relationship between Employer and Employee as
established by this Agreement does not, and shall not be construed to, alter or
in any way affect the legal, ethical, and professional relationship between
Employee and patients cared for by Employee, nor shall anything contained in
this Agreement abrogate any right, privilege, or obligation arising out of or
applicable to the physician-patient relationship.

         6. CLINICAL RECORDS. Employee shall assure that appropriate clinical
records are prepared with regard to all professional services provided by
Employee under this Agreement. All such records shall be prepared and
maintained according to prudent record keeping procedures and as required by
law. All clinical records prepared and maintained with regard to services
rendered under this Agreement shall be and remain the property of Employer,
notwithstanding any termination of this Agreement.

         7. PROFESSIONAL LIABILITY INSURANCE. Employer shall, at all times
during the initial and any renewal term of this Agreement, provide at its sole
cost and expense professional and general liability insurance coverage for
Employee in such amounts and with such carrier or carriers as Employer shall
deem necessary and appropriate.

<PAGE>   45

         8. EXPENSES. Ordinary and necessary business expenses incurred by
Employee in performing his or her duties under this Agreement, including but
not limited to professional dues, subscriptions, licenses, and continuing
education expenses, shall be borne by Employer.

         9. EMPLOYEE BENEFITS. Employee shall be entitled to receive or
participate in all employee benefits generally available to employees of
Employer in accordance with the terms of the Employer's employee benefit plans
in effect from time to time. The governing body of Employer may increase,
decrease, or discontinue any benefit plan at any time without notice to or the
consent of Employee.

         10. TERM. The initial term of this Agreement shall begin on the
Effective Date stated on page 1 hereof, and shall terminate on the next ensuing
December 31. This Agreement shall thereafter automatically renew for successive
terms of one (l) year each unless and until terminated as hereinafter provided.

         11. VOLUNTARY TERMINATION. Either party may terminate this Agreement
at any time, with or without cause, by giving written notice thereof to the
other party at least ninety (90) days prior to the effective date of
termination.

         12. TERMINATION FOR CAUSE. Employer may terminate this Agreement
immediately upon written notice to Employee on the occurrence any of the
following events:

                 (a) The failure of Employee to correct any material breach of
         this Agreement to the reasonable satisfaction of Employer within
         thirty (30) days following written notice from Employer specifying
         such breach;

                 (b) The revocation, termination, restriction, or suspension of
         Employee's license to practice his or her profession in the State of
         Tennessee, Employee's DEA permit (if applicable), or the exclusion of
         Employee from participation in Medicare, Medicaid, or CHAMPUS; or

                 (c) Any unprofessional or illegal conduct by Employee which
         makes the performance of this Agreement impractical, including, but
         not limited to, the conviction of a felony.

         13. COVENANT NOT TO COMPETE. (a) Employee agrees and covenants that,
during the term of this Agreement and for a period of five (5) years after
termination of this Agreement, Employee shall not, either directly as a
partner, employer, agent, independent contractor, employee or indirectly
through a corporation, partnership, affiliate, subsidiary or otherwise:
         
                 (i) Establish, operate or provide professional medical 
         services substantially similar to those provided for Employer pursuant
         to his employment relationship with Employer ("Prohibited Services") 
         at any medical office, clinic or other health care facility at any 
         location within Knox County, Tennessee (the "Restricted Territory");


<PAGE>   46
         
                    (ii) Publicly announce or offer (by any method) to
         provide Prohibited Services within the Restricted Territory;
         
                    (iii) Solicit, induce or attempt to induce patients
         of any physician (including Employee) associated or affiliated
         with Employer to leave the care of physicians associated or
         affiliated with Employer; or

Employer acknowledges and agrees that nothing in the foregoing will be
construed to restrict the Employee from (i) delivering physician services that
are unrelated to the fields of hematology or oncology, including the practice
of internal medicine, (ii) teaching hematology or oncology, or (iii) assuming
directorships of hospices following termination of this Agreement.

         (b) If Employee violates the covenants set forth in this Section 13,
then the duration of the restrictions contained herein shall be extended an
additional month for each month during which such violation occurred but was
not discovered by Employer, beginning upon the date that Employer learns of the
violation and so notifies Employee in writing.

         (c) Employee acknowledges and agrees that the covenants contained in
this Section 13 are necessary to protect the business and goodwill of Employer
and that a breach of these covenants will result in irreparable harm and
continuing damage to Employer.  As a result, Employee agrees that if Employee
breaches or threatens to breach these covenants, Employer shall be entitled to
specific performance and/or injunctive or other equitable relief in order to
prevent the continuation of such harm, as well as money damages. Employee
waives any requirement for the securing or posting of any bond in connection
with the obtaining of any such equitable relief.

         (d) Employee acknowledges and agrees that if Employee breaches the
covenants contained in this Section 13 after the Fifteenth (15th) anniversary
of this Agreement, and Employer is unable for any reason to obtain a
restraining order from a court of competent jurisdiction within thirty (30)
days after application to enjoin the breach by Employee, it will be difficult
to calculate the precise amount of damages suffered by Employer. As a result,
the parties have determined that, in the event of such a breach, Employer shall
be entitled to liquidated damages equal to the lesser of (i) fifty percent
(50%) of the total amount of professional service revenues attributable to
Employee during the three years prior to the termination of this Agreement, or
(ii) fifty percent (50%) of the total professional services revenues earned by
the Employee from the competing activity during the three years immediately
following such violation.  Any amount payable pursuant to the immediately
preceding sentence shall be paid by Employee in three (3) installments no later
than the 15th day of the third month following each of the first three
anniversaries of such violation.

         (e) The parties have attempted to limit the provisions of this Section
13 only to the extent necessary to protect each party's interests. However, the
parties hereby agree that, in the event that any provision, section or
subsection of this Section 13 is adjudged by any court of competent





<PAGE>   47





jurisdiction to be void or unenforceable, in whole or part, such court shall
modify and enforce any such provision, section or subsection to the extent that
it believes to be reasonable under the circumstances.

         14. NOTICES. Any notice required or permitted under the terms of this
Agreement shall be in writing and shall delivered by any reasonable means,
which may include but is not limited to hand delivery or United States Mail.
Any notice given by United States Mail shall be effective on the mailing date.
Notice given by any other reasonable means, including hand delivery, shall be
effective on receipt.

         15. ENTIRE AGREEMENT. This Agreement contains the entire agreement
between the parties relating to the subject matter addressed herein. Any prior
or contemporaneous agreement, promise, or representation, whether oral or
written, relating to the subject matter of this Agreement and not expressly set
forth or referenced in this Agreement or a proper amendment hereto shall be of
no force or effect.

         16. AMENDMENT. This Agreement may be amended only by the mutual
written consent of the parties, and no oral modification or amendment shall be
permitted.

         17. ASSIGNMENT. This Agreement and Employee's rights and obligations
hereunder may not be assigned or transferred by Employee. Employer may assign
this Agreement, and its rights and obligations hereunder, to any person that
controls, is controlled by, or is under common control with Employer, or which
is merged with or into Employer, or that purchases all or substantially all of
the assets of Employer.

         18. BINDING EFFECT. This Agreement shall be binding upon and shall
inure to the benefit of the respective parties hereto and their successors and
permitted assigns.

         19. WAIVER. Any of the terms or conditions of this Agreement which may
be waived may be waived in writing at any time by any party hereto which is
entitled to the benefit thereof. Waiver of breach of any provision of this
Agreement shall not be deemed a waiver of any other breach of the same or a
different provision.

         20. REMEDIES. Nothing in this Agreement shall be construed to limit
the lawful remedies available to either party in the event of breach of any
provision of this Agreement. The provisions of this Agreement and the
performance of each party hereunder may be enforced by any right or remedy
available at law or in equity.

         21. SEVERABILITY. In the event that any provision of this Agreement is
rendered invalid or unenforceable, such provision shall be severed from this
Agreement and the remaining provisions of this Agreement shall continue in full
force and effect, provided, however, that if the effect of the severance of
such unenforceable provision is to substantially deprive Employer of the
benefit of the services of Employee or the revenues derived therefrom, or to
substantially deprive





<PAGE>   48




Employee of the benefit of compensation for services rendered, this Agreement
may be terminated by the party so deprived immediately upon written notice to
the other party.

         22. HEADINGS OR CAPTIONS. The headings or captions provided throughout
this Agreement are for reference purposes only, shall not be considered in
construing the terms and conditions of this Agreement, and shall not in any way
affect the meaning or interpretation of this Agreement.

         23. SCHEDULES AND EXHIBITS. The schedules and exhibits referenced in
this Agreement are an essential part of the agreement of the parties, and shall
be considered for all purposes a part of this Agreement. Any and all
counterparts, photocopies, or other reproductions of this Agreement shall
include all of its schedules and exhibits, attached to and made a part of the
Agreement.

         24. GOVERNING LAW. This Agreement shall be governed by and construed
in accordance with the law of the State of Tennessee.

         25. COUNTERPARTS. This Agreement may be executed in any number of
counterparts, each of which shall be deemed to be an original.





<PAGE>   49




                 IN WITNESS WHEREOF, the parties hereto have executed this
Agreement as of the day and year first written above.


                            KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C.
                            ("EMPLOYER")



                            By:
                               ---------------------------------------
                                Allan M. Grossman, M.D.




                                                                      , M.D.
                            ------------------------------------------
                            ("EMPLOYEE")




<PAGE>   50





                                  SCHEDULE A


                           COMPENSATION OF EMPLOYEE

         Employee shall be entitled to receive, throughout the term of this
Agreement, compensation determined in accordance with the formula approved from
time to time by the Members of Employer or as otherwise approved by the Members
of Employer.

THIS SCHEDULE IS AN ESSENTIAL PART OF THE AGREEMENT OF THE PARTIES AND MUST BE
INCLUDED WITH ANY AND ALL COPIES OF THE AGREEMENT
                                                (Initial)     Employer: ________



<PAGE>   1
                                                                   EXHIBIT 10(r)





                               SERVICE AGREEMENT

                                  BY AND AMONG

                            RESPONSE ONCOLOGY, INC.

               KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C.

                                      AND

         MEMBERS OF KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C.

                                 APRIL 12, 1996
<PAGE>   2

                               SERVICE AGREEMENT

         THIS SERVICE AGREEMENT dated as of April 12, 1996 by and among
RESPONSE ONCOLOGY, INC., a Tennessee corporation ("Response"), KNOXVILLE
HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C., a Tennessee professional limited
liability company (the "Provider") and THE MEMBERS OF KNOXVILLE
HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C. (the "Members").

                                  RECITALS:

         WHEREAS, Response is in the business of owning certain assets of and
managing and operating medical clinics, and providing support services to and
furnishing medical practices with the necessary facilities, equipment,
personnel, supplies and support staff to operate a medical practice;

         WHEREAS, effective April 12, 1996, Response and the Members will
execute a definitive agreement (the "Purchase Agreement") pursuant to which
Response will contract to acquire from the Members all of their rights, title
and interests in and to the medical partnership operating as Knoxville
Hematology-Oncology Associates (the "Group");

         WHEREAS, the Members have formed the Provider for the purpose of
continuing their medical practice following consummation of the transaction
contemplated by the Purchase Agreement;

         WHEREAS, the Provider and the Members desire to retain Response to
perform the practice management functions described herein in order to permit
the Provider and the Members to devote substantially full time and efforts on a
concentrated and continuous basis to the rendering of medical services to
patients;

         NOW THEREFORE, in consideration of the premises and the mutual
covenants and agreements herein contained, effective April 12, 1996, the
Provider, the Members and Response agree to the terms and conditions provided
in this Agreement.

                                   ARTICLE 1.
                          RELATIONSHIP OF THE PARTIES

         1.1.  Independent Relationship.  The Provider and Response intend to
act and perform as independent contractors, and the provisions hereof are not
intended to create any partnership, joint venture, agency or employment
relationship between the parties.  Notwithstanding the authority granted to
Response herein, Response and the Provider agree that the Provider shall retain
the authority to direct the medical, professional, and ethical aspects of its
medical practice.  Each party shall be solely responsible for and shall comply
with all state and federal laws pertaining to employment taxes, income
withholding, unemployment compensation contributions and other employment
related statutes applicable to that party.

         1.2.  Responsibilities of the Parties.  As more specifically set forth
herein, Response shall provide the Provider with offices and facilities,
equipment, supplies, support personnel, and management and financial advisory
services.  As more specifically set forth herein, the Provider shall be
responsible for the recruitment and hiring of Physicians and all issues related
to medical practice patterns and documentation thereof.  Notwithstanding
anything herein to the contrary, no "designated health service" as defined in
42 U.S.C. Section 1395nn, including any amendments or successors thereto, shall
be provided by Response under this Agreement.
<PAGE>   3

         1.3.  Provider's Matters.  Matters involving the internal agreements
and finances of the Provider, including the distribution of professional fee
income among the individual Physician Members (as hereinafter defined), tax
planning, and pension and investment planning (and expenses relating solely to
these internal business matters), hiring, firing and licensing of Non-physician
Employees (hereinafter defined) shall remain the sole responsibility of the
Provider and the individual Physician Members.

         1.4.  Patient Referrals.  The parties agree that the benefits to the
Provider hereunder do not require, are not payment for, and are not in any way
contingent upon the admission, referral or any other arrangement for the
provision of any item or service offered by Response to any of the Provider's
patients in any facility or laboratory controlled, managed or operated by
Response.

         1.5.  Professional Judgment.  Each of the parties acknowledges and
agrees that the terms and conditions of this agreement pertain to and control
the business and financial relationship between and among the parties but do
not pertain to and do not control the professional and clinical relationship
between and among the Provider, the Provider's Employees, and the Provider's
patients.  Nothing in this Agreement shall be construed to alter or in any way
affect the legal, ethical and professional relationship between and among the
Provider and the Provider's patients, nor shall anything contained in this
Agreement abrogate any right, privilege, or obligation arising out of or
applicable to the physician-patient relationship.


                                   ARTICLE 2.
                                  DEFINITIONS

         2.1.  Definitions.  For the purposes of this Agreement, the following
definitions shall apply:

         Financial and Accounting Definitions:

                 (a)  "Account Debtor" shall mean an account debtor or any
                 other Person obligated in respect of an Account Receivable.

                 (b)  "Accounts Receivable" shall mean, with respect to the
                 Provider, all accounts and any and all rights to payment of
                 money or other forms of consideration of any kind now owned or
                 hereafter acquired (whether classified under the Uniform
                 Commercial Code as accounts, chattel paper, general
                 intangibles, or otherwise) for goods sold or leased or for
                 services rendered by the Provider, including, but not limited
                 to, accounts receivable, proceeds of any letters of credit
                 naming the Provider as beneficiary, chattel paper, insurance
                 proceeds, contract rights, notes, drafts, instruments,
                 documents, acceptances, and all other debts, obligations and
                 liabilities in whatever form from any other Person, provided
                 that cash, checks and credit card purchases are not included
                 in the definition of Accounts Receivable.

                 (c)  References to "amounts recorded" shall mean all amounts
                 recorded or recordable in accordance with GAAP (hereinafter
                 defined), including, without limitation, all billed Physician
                 Services Revenue hereinafter defined and Non-Physician Revenue
                 hereinafter defined, earned Capitation Revenue hereinafter
                 defined and all expenses that are subject to accrual under
                 GAAP.

                 (d)  "Annual Surplus" shall mean Practice Revenue (hereinafter
                 defined) less the sum of the Base Service Fee (hereinafter
                 defined), Practice Retainage (hereinafter defined) and
                 Non-physician Employee Compensation (hereinafter defined).
<PAGE>   4

                 (e)  "Bad Debt Allowance" shall mean, with respect to Accounts
                 Receivable, an allowance for uncollectible Accounts Receivable
                 determined based on a methodology approved by the Oversight
                 Committee.

                 (f)  "Base Service Fee" shall mean the base fee set forth on 
                 Schedule A hereto.

                 (g)  "Base Fee" shall mean an amount payable monthly to
                 Response by the Provider equal to the Base Draw set forth on
                 Schedule A.

                 (h)  "Capitation Revenue" shall mean amounts recorded
                 consisting of revenue from managed care organizations, where
                 payment is made periodically on a per member basis,
                 administration payments, co-payments and all other payments by
                 managed care organizations, including, without limitation,
                 managed care variable expense bonuses, hospital expense
                 bonuses or any other bonus or payment which rewards the
                 Provider for its medical performance under any managed care
                 arrangement.

                 (i)  "Clinic Expenses" shall mean all amounts recorded
                 comprising the expenses incurred in the operation of any
                 Clinic, including, without limitation:

                          (A)  salaries, benefits and other direct costs of any
                          Executive Director employed pursuant to Section 5.6
                          below and all personnel employed by Response at a
                          Clinic, including Non-physician Employee
                          Compensation;

                          (B)  obligations of Response under leases or
                          subleases of facilities and personal property
                          utilized by the Provider, including, without
                          limitation, Clinics and medical offices, medical,
                          laboratory and other equipment utilized by the
                          Provider;

                          (C)  personal property and intangible taxes assessed
                          against properties and assets utilized by the
                          Provider or otherwise deployed in any Clinic
                          commencing on the date of this Agreement; and

                          (D)  other ordinary, necessary and reasonable
                          expenses incurred by Response in carrying out its
                          obligations under this Agreement, including, without
                          limitation, depreciation on equipment utilized in the
                          Clinics, interest on secured loans (other than notes
                          payable by Response to any Member or his/her assigns
                          arising out of the Purchase Agreement) incurred to
                          purchase Clinic equipment, insurance (except
                          professional liability of physicians, which will
                          remain a physician expense), laundry, supplies, cost
                          of goods sold from inventory, utilities, telephone
                          service, printing, stationery, advertising, postage,
                          medical transcribing and waste deposal.

                 All Clinic Expenses shall be computed in accordance with GAAP.
                 To the extent expenses incurred benefit multiple clinics, such
                 Clinic Expenses shall be allocated among such Clinics
                 benefitting from such expenditure as Response shall reasonably
                 determine with the approval of the Oversight Committee.
                 Clinic Expenses shall not include (i) any corporate overhead
                 charges of Response, (ii)  the cost of any capital
                 expenditures incurred by Response pursuant hereto, except to
                 the extent of depreciation, amortization (except amortization
                 of the Service Agreement Intangible (hereinafter defined)
                 which shall not be a Clinic Expense), interest and other
                 period charges under GAAP in respect of such capital
                 expenditures, (iii) any federal or state income taxes, (iv)
                 base rental payments under any sub-lease arrangement and (v)
                 any expenses which are expressly designated herein as expenses
                 or responsibilities of and
<PAGE>   5

                 are paid by the Provider; provided, however, that in the case
                 of Non-physician Employee Compensation, such expenses shall be
                 Clinic Expenses notwithstanding the obligation of the  
                 Provider to pay same.

                 (j)  "Fee Adjustment" shall mean any adjustment for any
                 discount, non-allowed contractual or other adjustment under
                 Medicare, Medicaid, any preferred provider plan, workers'
                 compensation plan, employee/dependent health care benefit
                 program or other contractual arrangement between the Provider
                 and any Third Party Payor, and any professional courtesy or
                 other reasonable and customary discount that results in fee
                 revenue not being collected.

                 (k)  "GAAP" shall mean generally accepted accounting
                 principles set forth in the opinions and pronouncements of the
                 Accounting Principles Board of the American Institute of
                 Certified Public Accountants and statements and pronouncements
                 of the Financial Accounting Standards Board or in such other
                 statements by such other entity or other practices and
                 procedures as may be approved by a significant segment of the
                 accounting profession or prescribed by the Securities and
                 Exchange Commission, which are applicable to the circumstances
                 as of the date of determination.  For purposes of this
                 Agreement, GAAP shall be applied in a manner consistent with
                 the historic practices used by Response.

                 (l)  "Governmental Receivables" shall mean an Account
                 Receivable of the Provider which (i) arises in the ordinary
                 course of business of the Provider, (ii) has as its Third
                 Party Payor the United States of America or any state or any
                 agency or instrumentality of the United States of America or
                 any state which makes any payments with respect to Medicare or
                 Medicaid or with respect to any other program (including
                 CHAMPUS) established by federal or state law, and (iii) is
                 required by federal or state law to be paid or to be made to
                 the Provider as a health care provider.  Governmental
                 Receivables shall not, however, refer to amounts payable by
                 private insurers under contract to provide benefits under the
                 Federal Employee Health Benefit Program.

                 (m)  "Non-Physician Revenue" shall mean all amounts recorded
                 as fees (net of Fee Adjustments and Bad Debt Allowance) by or
                 on behalf of either the Provider or Response which are not
                 Physician Services Revenue or Capitation Revenue, but
                 excluding any interest, investment, rental or similar payments
                 or income made or payable to the Provider or Response that are
                 unrelated to the provision of medical services or products.

                 (n)  "Performance Fee" shall mean an amount payable to
                 Response on a calendar-year basis as computed pursuant to the
                 formula set forth in Schedule A hereto.

                 (o)  "Non-physician Employee Compensation" shall mean all
                 amounts recorded as salaries, wages (including overtime),
                 benefits, payroll taxes and other compensation expense by the
                 Provider in respect of Physician Extender Personnel
                 (hereinafter defined) and Technical Employees (hereinafter
                 defined) who are Non-physician Employees (hereinafter
                 defined), to the extent such amounts are required to be paid
                 by the Provider under Applicable Law or the reimbursement
                 policies of any Third Party Payor.

                 (p)  "Physician Expense" shall mean the sum of (i) salaries,
                 bonuses and other compensatory payments to Physicians
                 (hereinafter defined) employed by or otherwise performing
                 services for the Provider, including Physician Members; (ii)
                 perquisites and benefits provided to such persons; (iii)
                 travel and entertainment expense, continuing
<PAGE>   6

                 education expense, professional liability expense and other
                 expenses and payments that primarily benefit such persons;
                 provided, however, that any such expense incurred at the
                 direction of Response shall not be a Physician Expense and
                 shall instead be a Clinic Expense; and (iv) payroll taxes in
                 respect of any of the foregoing.

                 (q)  "Physician Services Revenue" shall mean (a) all amounts
                 recorded as fees (net of Fee Adjustments and Bad Debt
                 Allowance) by or on behalf of the Provider as a result of
                 professional medical services furnished to patients by
                 Non-physician Employees and Physician Extender Personnel,
                 whether rendered in an inpatient or outpatient setting plus
                 (b) Capitation Revenue, and excluding any items approved
                 pursuant to Section 4.2(c) below.

                 (r)  "Practice Retainage" shall mean an amount equal to the
                 percentage of Practice Revenue set forth on Schedule A hereto.

                 (s)  "Practice Revenue" shall mean the sum of all amounts
                 recorded by the Provider as Physician Services Revenue,
                 Non-Physician Revenue, Capitation Revenue and other revenue
                 attributable to the conduct of the Provider's medical
                 practice, but shall specifically exclude profits from any
                 investment of the Provider in any partnership, joint venture,
                 corporation, limited liability company and any other revenue
                 not derived from the providing of services by employees of the
                 Provider or Response.

                 (t)  "Service Fees" shall mean the sum of the Base Service Fee
                 and the Performance Fee (if any).

         Other Definitions:

                 (u)  An "Affiliate" of a corporation shall mean (a) any person
                 or entity directly or indirectly controlled by such
                 corporation, (b) any person or entity directly or indirectly
                 controlling such corporation, (c) any subsidiary of such
                 corporation if the corporation has a fifty percent (50%) or
                 greater ownership interest in the subsidiary, or (d) such
                 corporation's parent corporation if the parent has a fifty
                 percent (50%) or greater ownership interest in the
                 corporation.  For purposes of this Section 2.1(u), the
                 Provider is not an affiliate of Response.

                 (v)  "Applicable Law" shall mean all applicable provisions of
                 constitutions, statutes, rules, regulations, ordinances and
                 orders of all Governmental Authorities and all orders and
                 decrees of all courts, tribunals and arbitrators, and shall
                 include, without limitation, Health Care Law.

                 (w)  "CHAMPUS" shall mean the Civilian Health and Medical
                 Program of the Uniformed Services.

                 (x)  "Clinic" shall mean the practice facility currently
                 utilized by the Provider, and any facility, related business
                 and all medical group business operations which the Provider
                 and Response may, in the future, mutually agree to
                 characterize as a Clinic.

                 (y)  "Employment Agreement" shall mean an employment agreement
                 between each physician now or hereinafter employed by the
                 Provider and the Provider pursuant to which the physician
                 shall be employed by the Provider to provide medical services
                 on behalf of the Provider, which Employment Agreement shall be
                 substantially in the form set forth as Exhibit 2.1(y) hereto.
<PAGE>   7

                 (z)  "Governmental Authority" shall mean any national, state
                 or local government (whether domestic or foreign), any
                 political subdivision thereof or any other governmental,
                 quasi-governmental, judicial, public or statutory
                 instrumentality, authority, board, body, agency, bureau or
                 entity or any arbitrator with authority to bind a party at law.

                 (aa)  "Group" shall mean Knoxville Hematology & Oncology
                 Associates, a Tennessee general partnership of which the
                 Members were the sole general partners and which, prior to
                 consummation of the Purchase Agreement, conducted the medical
                 practice of the Members.

                 (ab)  "Health Care Law" shall mean any Applicable Law
                 regulating the acquisition, construction, operation,
                 maintenance or management of a health care practice, facility,
                 provider or payor, including without limitation 42 U.S.C.
                 Section 1395 nn and 42 U.S.C. Section 1320a-7b.

                 (ac)  "Liquidated Damages Amount" shall mean an amount equal
                 to the Liquidated Damages Amount set forth on Schedule A
                 hereto.

                 (ad)  "Medicaid" shall mean any state program pursuant to
                 which health care providers are paid or reimbursed for care
                 given or goods afforded to indigent persons and administered
                 pursuant to a plan approved by the Health Care Financing
                 Administration under Title XIX of the Social Security Act.

                 (ae)  "Medicare" shall mean any medical program established
                 under Title VIII of the Social Security Act and administered
                 by the Health Care Financing Administration.

                 (af)  "Member" shall mean each Member of the Provider as of 
                 the date hereof.

                 (ag)  "Necessary Authorization" shall mean with respect to the
                 Provider all certificates of need, authorization,
                 certifications, consents, approvals, permits, licenses,
                 notices, accreditations and exemptions, filings and
                 registrations, and reports required by Applicable Law,
                 including, without limitation, Health Care Law, which are
                 required, necessary or reasonably useful to the lawful
                 ownership and operation of the Provider's business.

                 (ah)  "Oversight Committee" shall mean a seven (7) member
                 committee established pursuant to Section 4.1.  Except as
                 otherwise provided, the act of a majority of the members of
                 the Oversight Committee shall be the act of the Oversight
                 Committee.

                 (ai)  "Person" shall mean an individual, corporation,
                 partnership, joint venture, trust, association, or
                 unincorporated organization, or a government or any agency or
                 political subdivision thereof including, without limitation, a
                 Third Party Payor.

                 (aj)  "Physician" shall mean all medical doctors employed by
                 the Provider or with whom the Provider has entered into
                 independent contractor or other non-employee relationships, and

                 (ak)  "Non-physician Employees" shall mean all persons other
                 than Physicians who deliver billable medical or health care
                 services under the direction of the Provider and its
                 Physicians or are otherwise under contract with the Provider
                 to provide professional services to Clinic patients and, in
                 each case, who are duly licensed to provide professional
                 medical services in the State of Tennessee and all Technical
                 Employees.
<PAGE>   8

                 Such definition may include Physician Extender Personnel to
                 the extent such Physician Extender Personnel are required by
                 Applicable Law or reimbursement policies of any Third Party
                 Payor to be employed by the Provider.

                 (al)  "Physician Extender Personnel" shall mean employees of
                 Response who deliver services to the Provider, including
                 without limitation nurse anesthetists, physician assistants,
                 registered and licensed practical nurses, nurse practitioners,
                 psychologists, and other such persons, other than physicians,
                 who are not Non-physician Employees.

                 (am)  "Physician Members" shall mean those Physicians who are
                 from time to time hereafter members of the Provider.

                 (an)  "Practice Assets" shall have the meaning ascribed to
                 that term in Section 11.5 of this Agreement.

                 (ao)  "Provider" shall mean Knoxville Hematology-Oncology
                 Associates, P.L.L.C., a Tennessee professional limited
                 liability company operating a group medical practice in the
                 general oncology specialty.

                 (ap)  "Provider Event of Default" shall have the meaning
                 ascribed to such term in Section 11.4 hereof.

                 (aq)  "Purchase Agreement" shall mean that certain Purchase
                 and Sale Agreement dated as of April 12, 1996 by and among
                 Response and the Members.

                 (ar)  "Remaining Physician Member" shall mean any Physician
                 Member who shall have been a Member at the effective time of
                 this Agreement and who, at any time within one (1) year prior
                 to the occurrence of a Provider Event of Default shall have
                 been a Physician Member; provided, however, that such term
                 shall not include any Member who shall have, within such one
                 year period, ceased to be a Physician Member by reason of such
                 Physician Member's withdrawal as a Physician Member of the
                 Provider under circumstances which, in the reasonable judgment
                 of Response, did not have as a primary purpose the avoidance
                 of the provisions of Section 11.6 hereof, or by reason of such
                 Physician Member's death, disability or retirement at normal
                 retirement age.

                 (as)  "Response" shall mean Response Oncology, Inc., a
                 Tennessee corporation incorporated on June 26, 1984 under the
                 name Biotherapeutics Incorporated, whose name was changed to
                 Response Technologies, Inc. by Charter amendment on October
                 30, 1989, and subsequently to Response Oncology, Inc. by
                 Charter amendment on November 1, 1995, and its wholly owned
                 subsidiaries, including the Group.

                 (at)  "Response Event of Default" shall have the meaning
                 ascribed to such term in Section 11.3 of this Agreement.

                 (au)  "Technical Employees" shall mean technicians who provide
                 services in the diagnostic areas of the Provider's practice,
                 such as employees of any Clinic laboratory, radiology
                 technicians and cardiology technicians.  All Technical
                 Employees shall be Non-physician Employees.

                 (av)  "Third Party Payor" shall mean each Person which makes
                 payment under a Third Party Payor Program, and each Person
                 which administers a Third Party Payor Program.
<PAGE>   9

                 (aw)  "Third Party Payor Program" shall mean Medicare,
                 Medicaid, CHAMPUS, insurance provided by Blue Cross and/or
                 Blue Shield, managed care plans, and any other private health
                 care insurance programs and employee assistance programs as
                 well as any future similar programs.

                                   ARTICLE 3.
                     FACILITIES TO BE PROVIDED BY RESPONSE

         3.1.  Facilities.  Response shall provide to the Provider for its use
in its group medical practice the offices and facilities more fully described
in Exhibit 3.1 hereto, the furnishings, fixtures and equipment located
thereupon, and shall pay all costs (all of which shall be Clinic Expense) of
repairs, maintenance and improvements, utility (telephone, electric, gas,
water) expenses, normal janitorial services, refuse disposal and all other
costs and expenses reasonably incurred in conducting the operations
contemplated by this Agreement in each Clinic during the term of this
Agreement, including, without limitation, related real or personal property
lease cost payments and expenses, taxes and insurance.  The Provider shall
comply with all terms and provisions of any lease or other agreement with
respect to such facility.  Response shall maintain such facility and equipment
used by the Provider in updated, fully operational condition, ordinary wear and
tear excepted.  Response shall consult with the Provider regarding the
condition, use and needs for the offices, facilities and improvements, and any
purchase, lease or improvement of any offices, facilities or improvements, or
change in any of the foregoing, shall be as directed and/or approved by a
majority of the Oversight Committee.  Response shall follow all reasonable
directions of the Oversight Committee in respect of improvements to the
offices, facilities and equipment to be used by the Provider.  The Provider
shall not amend, modify or terminate any sub-lease agreements without the prior
written consent of Response.

         3.2     Use of Facilities.  The Provider shall not use or occupy any
facility owned or leased by Response for any purpose which is prohibited by any
Applicable Law, this Agreement, or the terms of any lease or other arrangement
with respect to the use or occupancy of such facility, or which may be
dangerous to life, limb, or property (except medical services provided in the
ordinary course of business), or which would increase the fire or extended
coverage insurance rate on such facility.

                                   ARTICLE 4.
                       DUTIES OF THE OVERSIGHT COMMITTEE

         4.1.  Formation and Operation of the Oversight Committee.  The parties
shall establish an Oversight Committee which shall be responsible for
developing management and administrative policies for the overall operation of
each Clinic.  The Oversight Committee shall consist of seven (7) members.
Response shall designate, and shall have the right to remove and replace, in
its sole discretion, three (3) members of the Oversight Committee.  The
Provider shall designate, and shall have the right to remove and replace, in
its sole discretion, four (4) members of the Oversight Committee.  The
Oversight Committee shall have the authority to adopt bylaws (which shall
include the fixing of a quorum for the conduct of business by the Oversight
Committee), establish regular meeting times and places, call special meetings
for any purpose and elect a chairman and a secretary who shall preside over and
record, respectively, the proceedings at any meeting of the Oversight
Committee.  Except as otherwise provided herein, the affirmative vote of a
majority of the members of the Oversight Committee shall be required for
approval of any action taken thereby.

         4.2.  Duties and Responsibilities of the Oversight Committee.  The
Oversight Committee shall have the following duties and obligations:

                 (a)  Capital Improvements and Expansion.  Any renovation and
                 expansion plans and capital equipment expenditures with
                 respect to any Clinic shall be reviewed and
<PAGE>   10

                 approved by the Oversight Committee and shall be based upon
                 economic feasibility, physician support, productivity and then
                 current market conditions.

                 (b)  Annual Budgets.  All annual capital and operating budgets
                 prepared by Response, as set forth in Section 5.2, shall be
                 subject to the review and approval of the Oversight Committee,
                 which shall have the authority to reject individual items in
                 the budget and to fix such amounts so rejected; provided,
                 however, that in the event the Oversight Committee exercises
                 such authority and increases any budget amount by more than
                 ten (10%) percent of the amount proposed by Response and does
                 not propose a commensurate reduction in other budget items
                 reasonably acceptable to Response, then such modification
                 shall be approved by a vote of five-sevenths (5/7) of the
                 Oversight Committee.

                 (c)  Exceptions to Inclusion in the Physician Services
                 Calculation.  The exclusion of any revenue from Practice
                 Revenue, whether now or in the future, shall be subject to the
                 approval by a vote of five-sevenths (5/7) of the Oversight
                 Committee.  Current approved exceptions are listed in the
                 attached Exhibit 4.2(c).

                 (d)  Advertising.  All advertising and other marketing of the
                 services performed at any Clinic shall be subject to the prior
                 review and approval of the Oversight Committee.

                 (e)  Patient Fees; Collection Policies.  As a part of the
                 annual operating budget, in consultation with the Provider and
                 Response, to the extent allowed by Applicable Law, the
                 Oversight Committee shall review and advise the Provider as to
                 an appropriate fee schedule for all physician and ancillary
                 services rendered by the Provider, which fee schedule shall
                 ultimately be determined by the Provider in its sole
                 discretion.  In addition, the Oversight Committee shall
                 approve the credit collection policies of any Clinic.

                 (f)  Non-Physician Services.  The Oversight Committee shall
                 establish Clinic-provided non-physician services based upon
                 the pricing, access to and quality of such services.

                 (g)  Provider and Payor Relationships.  Decisions regarding
                 the establishment or maintenance of relationships with managed
                 care organizations, institutional health care providers and
                 Third Party Payors shall be made by the Oversight Committee in
                 consultation with Response and the Provider.

                 (h)  Strategic Planning.  The Oversight Committee shall
                 develop long-term strategic planning objectives.

                 (i)  Capital Expenditures.  The Oversight Committee shall
                 determine the priority of major capital expenditures
                 benefitting the Clinics.

                 (j)  Physician Hiring.  The Oversight Committee shall
                 determine the number and type of physicians required for the
                 efficient operation of each Clinic.  The approval of the
                 Oversight Committee shall be required for any variations to
                 the restrictive covenants in any physician employment
                 contract.

                 (k)  Executive Director.  The selection and retention of any
                 Executive Director pursuant to Section 5.6 and the salary and
                 cash fringe benefits of each Executive Director shall be
                 pursuant to the direction and control of the Oversight
                 Committee.  If the Provider is dissatisfied with the services
                 provided by any Executive Director, the Provider shall refer
                 the matter to the Oversight Committee.  The Oversight
                 Committee shall, in good faith,
<PAGE>   11

                 determine whether the performance of such Executive Director
                 could be brought to acceptable levels through counsel and
                 assistance, or whether the Executive Director's employment
                 should be terminated.

                                   ARTICLE 5.
               ADMINISTRATIVE SERVICES TO BE PROVIDED BY RESPONSE

         5.1.  Performance of Management Functions.  Response shall provide or
arrange for the services set forth in this Article 5, the cost of all of which
shall be paid by Response and included in Clinic Expenses.  Response is hereby
expressly authorized to perform its services hereunder in whatever manner it
deems reasonably appropriate to meet the day-to-day requirements of Clinic
operations in accordance with the general standards approved by the Oversight
Committee, including, without limitation, performance of some of the business
office functions at locations other than a Clinic.  The Provider will not act
in a manner which would prevent Response from efficiently managing the
day-to-day operations of each Clinic in a business-like manner.

         5.2.  Financial Planning and Goals.  Response shall prepare annual
capital and operating budgets reflecting in reasonable detail anticipated
revenue and expenses, sources and uses of capital for growth in the Provider's
practice and medical services rendered at each Clinic.  Response shall
determine the amount and form of capital to be invested annually in each Clinic
and shall specify the targeted profit margin for each Clinic which shall be
reflected in the overall budget.  Response realizes that a Clinic may realize
opportunities to provide new services and utilize new technologies that will
require capital expenditures and anticipates that such opportunities may
include ambulatory surgery centers, renovations to Clinic facilities, the
addition of satellite locations and new and replacement equipment pursuant to
Section 3.1, and Response agrees to provide funds to allow the Clinic to
provide such new services and to utilize such new technologies.  Such budgets
shall be presented to the Oversight Committee at least sixty (60) days prior to
the end of the preceding calendar year.  The Oversight Committee shall us its
best efforts to agree upon a budget at least thirty (30) days prior to the end
of such preceding Calendar year as provided in Section 4.2(b), and, once
approved in such manner, shall be binding upon Response and the Provider unless
modified or revised in like manner by the Oversight Committee.

         5.3.  Financial Statements.  Response shall prepare annual financial
statements on a cash basis for the separate operations of each Clinic and shall
prepare an annual pro-forma, accrual basis combined income statement for all
Clinics for purposes of determining the Annual Surplus.  If the Provider
desires an audit of any financial statement, the Provider may obtain such an
audit at its own expense.  Response shall prepare monthly unaudited financial
statements containing a combined balance sheet and statements of operations for
the Clinics, which shall be delivered to the Provider within thirty (30) days
after the close of each calendar month.  Notwithstanding the foregoing,
Response shall be under no obligation to keep multiple sets of books for cash
basis and accrual basis methods of accounting, but shall be entitled to keep
one set of books maintained on an accrual basis method of accounting, which
shall be converted by workpaper-only entries to the cash basis method of
accounting for purposes of preparing the cash basis financial statements
described above.

         5.4.  Inventory and Supplies.  Response shall order and purchase
reasonable and requested medical and office inventory and supplies required by
the Provider to provide quality services in the day-to-day operations of its
medical practice.

         5.5.  Management Services and Administration.

                 (a)  The Provider hereby appoints Response as its sole and
                 exclusive manager and administrator of all day-to-day business
                 functions connected with its group medical practice.  The
                 Provider agrees that the purpose and intent of this Service
                 Agreement is
<PAGE>   12

                 to relieve the Provider, the Physicians and Non-physician
                 Employees, to the maximum extent possible, of the
                 administrative, accounting, payroll, accounts payable,
                 personnel and business aspects of its practice, with Response
                 assuming responsibility for and being given all necessary
                 authority to perform these functions.  Response agrees that
                 the Provider, and only the Provider, will perform the medical
                 functions of its practice.  Response will have no authority,
                 directly or indirectly, to perform, and will not perform, any
                 medical function.  Response may, however, advise the Provider
                 as to the relationship between its performance of medical
                 functions and the overall administrative and business
                 functioning of its practice.  To the extent that they assist
                 the Provider in performing medical functions, all clinical
                 personnel performing patient care services obtained and
                 provided by Response shall be subject to the professional
                 direction and supervision of the Provider and, in the
                 performance of such medical functions, shall not be subject to
                 any direction or control by, or liability to, Response, except
                 as may be specifically authorized by the Provider.  The
                 Provider hereby indemnifies and holds Response, its officers,
                 directors, shareholders, agents and affiliates, their
                 successors and assigns ("Indemnified Persons") harmless, and
                 shall reimburse the Indemnified Persons for, from and against
                 each claim, loss, liability, cost and expense (including,
                 without limitation, interest, penalties, costs of preparation
                 and investigation, and the reasonable fees and disbursement
                 expenses of attorneys and other professional advisors)
                 directly or indirectly relating to, resulting from or arising
                 out of any medical function performed, or which should have
                 been performed, under the spervision of the Provider or
                 Non-physician Employees.

                 (b)  Response shall, on behalf of the Provider and under the
                 Provider's provider number, bill patients and Third Party
                 Payors, and shall collect the professional fees for medical
                 services rendered by the Provider in each Clinic, for services
                 performed outside a Clinic for the Provider's hospitalized
                 patients, and for all other professional and Clinic services.
                 Response's billing and collection practice shall be consistent
                 with those of comparable, nationally recognized, well managed
                 group medical practices.  The Provider hereby appoints
                 Response for the term hereof to be its true and lawful
                 attorney-in-fact, for the following purposes:  (i) to bill
                 patients in the Provider's name and on its behalf;  (ii) to
                 collect Accounts Receivable resulting from such billing in the
                 Provider's name and on its behalf; (iii)  to receive payments
                 from insurance companies, prepayments from health care plans,
                 and payments from all other Third Party Payors;  (iv) to take
                 possession of and endorse in the name of the Provider (and/or
                 in the name of an individual Physician, such payment intended
                 for purpose of payment of a Physician's bill) any notes,
                 checks, money orders, insurance payments and other instruments
                 received in payment of Accounts Receivable; and  (v) with the
                 advance consent of the Oversight Committee, to initiate legal
                 proceedings in the name of the Provider or any Physician to
                 collect any accounts and monies owed to the Provider, Clinic
                 or any Physician, to enforce the rights of the Provider or any
                 Physician as a creditor under any contract or in connection
                 with the rendering of any service, and to contest adjustments
                 and denials by any Governmental Authority (or its fiscal
                 intermediaries) as Third Party Payors.  All adjustments made
                 for uncollectible accounts, professional courtesies and other
                 activities that do not generate a collectible fee shall be
                 done in a reasonable and consistent manner.

                 (c)  Response shall design, supervise and maintain custody of
                 all files and records relating to the operation of each
                 Clinic, including but not limited to accounting, billing,
                 patient medical records, and collection records.  Patient
                 medical records shall at all times be and remain the property
                 of the Provider and shall be located at Clinic facilities so
                 that they are readily accessible for patient care.  The
                 Physicians shall have the obligation to oversee the
                 preparation and maintenance of patient medical records, and to
<PAGE>   13

                 provide such medical information as shall be necessary and
                 appropriate to the clinical function of such records, and to
                 maintain such records so as to ensure the availability of
                 Third-party Payor reimbursement for services rendered.  The
                 management of all files and records shall comply with
                 applicable state and federal statutes.  Response shall use its
                 best efforts to preserve the confidentiality of patient
                 medical records and use information contained in such records
                 only for the limited purpose necessary to perform the services
                 set forth herein; provided, however, in no event shall a
                 breach of said confidentiality be deemed a default under this
                 Agreement.  Response shall indemnify and hold the Provider
                 harmless from and against any monetary loss suffered by the
                 Provider on account of Response's breach of the foregoing
                 confidentiality provisions.

                 (d)  Response shall supply to the Provider necessary clerical,
                 accounting, payroll, bookkeeping and computer services,
                 laundry, linen, uniforms, printing, stationary, advertising,
                 postage and duplication services, medical transcribing
                 services and any other ordinary, necessary or appropriate item
                 or service for the operation of a Clinic, the cost of all of
                 which shall be Clinic Expense.

                 (e)  Subject to the provisions of Section 4.2(d), Response
                 shall design and implement adequate and appropriate public
                 relations programs on behalf of the Provider, with appropriate
                 emphasis on public awareness of the availability of services
                 at the Provider's Clinics.  Any public relations program shall
                 be conducted in compliance with applicable laws and
                 regulations governing advertising by medical professionals and
                 applicable canons or principles of professional ethics
                 governing the Provider and its physicians.

                 (f)  Response shall provide the data necessary for the
                 Provider to prepare its annual income tax returns and
                 financial statements, and shall provide payroll and related
                 services for Physicians and Non-physician Employees.
                 Response shall have no responsibility for the filing of such
                 tax returns, the payment of such income taxes or the cost of
                 preparation of income tax returns or financial statements on
                 behalf of the Provider or any physician employed thereby.

                 (g)  Response shall assist the Provider in recruiting
                 additional Physicians and Non- physician Employees, carrying
                 out such administrative functions as may be appropriate such
                 as advertising for and identifying potential candidates,
                 checking credentials, and arranging interviews; provided,
                 however, the Provider shall interview and make the ultimate
                 decision as to the suitability of any Physician or
                 Non-physician Employee to become associated with a Clinic.
                 All Physicians recruited by Response and accepted by the
                 Provider shall be the sole employees of the Provider, to the
                 extent such Physicians are hired as employees.  Subject to the
                 provisions of Section 6.4, any expenses incurred in the
                 recruitment of Physicians or Non-physician  Employees,
                 including, but not limited to, employment agency fees,
                 relocation and interviewing expenses, shall be Clinic
                 Expenses.

                 (h)  Subject to the provisions of Section 4.2(g), Response
                 shall negotiate and administer all managed care contracts on
                 behalf of the Provider.

                 (i)  Subject to the provisions of Sections 5.3 and 5.5(f),
                 Response shall arrange for legal and accounting services
                 related to Clinic operations incurred traditionally in the
                 ordinary course of business, including the cost of enforcing
                 any physician contract containing restrictive covenants,
                 provided such services shall be approved in advance by the
                 Executive Director.
<PAGE>   14

                 (j)  Response shall provide for the proper cleanliness of the
                 physical premises occupied and/or utilized by the Provider,
                 and maintenance and cleanliness of the equipment, furniture
                 and furnishings located upon such premises.

         5.6.  Executive Director.  Subject to the provisions of Section
4.2(k), Response shall recruit, hire and appoint an Executive Director to
manage and administer all of the day-to-day business functions of each Clinic
(it being understood and agreed that, if reasonable, a single Executive
Director may have responsibility for multiple Clinics).  Subject to Oversight
Committee approval, Response shall determine the salary, bonuses (if any) and
fringe benefits of each Executive Director, which salary, bonuses (which may be
payable in Response common stock or by issuance of options on Response common
stock) and benefits shall, to the extent the same are current expenses under
GAAP, be Clinic Expenses. At the direction, supervision and control of
Response, the Executive Director, subject to the terms of this Agreement, shall
implement the policies established by the Oversight Committee and shall
generally perform the duties and have the responsibilities of an administrator.
The Executive Director shall be responsible for organizing the agenda for the
meetings of the Oversight Committee referred to in Article 4.

         5.7.  Personnel.  Response shall provide Physician Extender Personnel
and other non-physician professional support (other than Technical Employees
and other persons who are required to be Non-physician  Employees) and
administrative personnel, clerical, secretarial, bookkeeping and collection
personnel reasonably necessary for the conduct of operations at each clinic.
Response shall determine and cause to be paid the salaries and fringe benefits
of all such personnel, which shall be Clinic Expenses.  Such personnel shall be
under the direction, supervision and control of Response, with those personnel
performing billable patient care services remaining employees of and being
subject to the professional supervision of the Provider.  If the Provider is
dissatisfied with the services of any person, the Provider shall consult with
Response.  Response shall in good faith determine whether the performance of
that employee could be brought to acceptable levels through counsel and
assistance, or whether such employee's employment should be terminated.  All of
Response's obligations regarding staff shall be governed by the overriding
principle and goal of providing the optimal quality of medical care consistent
with the efficient operation of the Clinic.  Employee assignments shall be made
to assure consistent and continued rendering of the optimal quality medical
support services consistent with the efficient operation of the Clinic and to
ensure prompt availability and accessibility of individual medical support
personnel to physicians in order to develop constant, familiar and routine
working relationships between individual physicians and individual members of
the medical support personnel.  Response shall maintain established working
relationships wherever possible and Response shall make every effort consistent
with sound business practices to honor the specific requests of the Provider
with regard to the assignment of its employees.

         5.8.  Events Excusing Performance.  Response shall not be liable to
the Provider for failure to perform any of the services required herein in the
event of strikes, lock-outs, calamities, acts of God, unavailability of
supplies or other events over which Response has no control for so long as such
events continue, and for a reasonable period of time thereafter.

         5.9.  Compliance with Applicable Laws.  Response shall comply with all
Applicable Law, in the conduct of its obligations under this Agreement.

         5.10.  Quality Assurance.  Response shall assist the Provider in
fulfilling its obligations to its patients to maintain the optimal quality of
medical and professional services consistent with the efficient operation of
the Clinic.

         5.11.  Provider Operating Account.  The Provider agrees to establish
and maintain a bank account, which shall be referred to as the Provider
Operating Account, for the purpose of (a) depositing Practice Revenue and
advances from the Receivables Line (defined below) pursuant to Section 5.12 and
<PAGE>   15

(b) paying (i) all expenses which are solely the obligation of the Provider,
including, without limitation, Physician Expense, up to the amount of Practice
Retainage, (ii) Clinic Expenses payable directly by the Provider (including,
without limitation, Non-physician Employee Compensation, (iii) the Clinic
Expense Portion of the Base Service Fee owed pursuant to Section 8.1 of this
Agreement, (iv) the Fixed Portion of the Base Service Fee owed pursuant to
Section 8.1 of this Agreement, and (v) other distributions to the Provider, and
the distributions shall be made in that order of payment.  To the extent
Practice Revenue of the Provider is insufficient to pay all amounts set forth
above, then any shortage shall be applied in reverse order to the order
provided above, with the Practice Retainage being the last item to be reduced
by such shortage.  The Provider hereby designates, constitutes and appoints the
Chief Financial Officer and Treasurer of Response as a signatory on the
Provider Operating Account, with full power and authority to sign checks and
cause drafts and other debits to be made on the Provider Operating Account in
the name of the Provider and to otherwise manage the cash resources and flow of
the Provider.  After the payment of all items described in clauses (b)(i)
through (iv) above, the Provider may withdraw amounts for distributions to
Physician Members.

         5.12.  Credit Line.  So long as the Provider is not in default
hereunder, Response shall from time to time during the term of this Agreement
advance to the Provider, in readily available United State funds, by wire
transfer, intrabank transfer or other electronic means, to be deposited into
the Provider Operating Account, up to an amount (the "Receivables Line")
determined from time to time equal to 100% of Accounts Receivable, net of any
Bad Debt Allowance and all Fee Adjustments with respect thereto, for the
purpose of paying the amounts required pursuant to Section 5.11(b)(i) through
(v).  Amounts advanced by Response under the Receivables Line will bear
interest at a rate equal to the prime or base lending rate quoted from time to
time by First Tennessee Bank National Association, plus one-half percent (.5%).
Amounts advanced by Response pursuant to this Section 5.12 shall be payable by
the Provider upon termination of this Agreement.  Response shall have the
authority from time to time pursuant to Section 5.11 above to make principal
payments on the Receivables Line.  Interest on the outstanding Receivables Line
will be computed on a daily basis based on the total unpaid and outstanding
advances on the Receivables Line.  Interest shall be payable to Response no
later than the fifth day of each month, in arrears.  Advances on the
Receivables Line will be secured by a security interest in and to Accounts
Receivable granted pursuant to Section 15.7 below.

         5.13.  Ancillary Services.  Response shall operate such ancillary
services as approved by the Oversight Committee.

                                   ARTICLE 6.
                          OBLIGATIONS OF THE PROVIDER

         6.1.  Professional Services.  The Provider shall provide professional
services to patients in compliance at all times with ethical standards, laws
and regulations applying to the medical profession, in a manner and to an
extent consistent with that established by the Provider prior to effectiveness
of this Agreement.  The Provider shall also make all reports and inquiries to
the National Practitioners Data Bank and/or any state medical licensing board
required by Applicable Law.  The Provider shall use its best efforts to ensure
that each Non-physician  Employee and Technical Employee associated with the
Provider to provide medical care to patients of the Provider is licensed by the
State of Tennessee to the extent required.  The Provider shall promptly notify
Response in writing, citing the underlying circumstances, in the event the
Provider or any Physician or Non-physician Employee associated therewith (i)
shall be or become the subject of any investigation into or proceeding with
respect to allegations of professional misconduct or incompetence; (ii) shall
be or become the subject of any investigation by any Federal or state
regulatory agency with respect to any possible violation of any Federal or
state law regulating the providing of health care services; (iii) shall be a
named party to any proceeding alleging violation of any law relating to such
person's professional activities or seeking to revoke such person's
professional license or privileges to practice in any hospital or medical
center; (iv) shall suffer revocation of such person's Medicare provider number,
professional license or privileges to practice in any hospital or medical
center.  In the event that any disciplinary action or medical
<PAGE>   16

malpractice action is initiated against any Physician or other person assisting
in the providing of medical services, the Provider shall immediately inform the
Executive Director of such action and the underlying facts and circumstances.
The Provider shall develop a program to monitor the quality of medical care
practiced at each Clinic. In that regard, the Provider shall at all times
supervise and assume primary professional responsibility for the delivery of
all medical or other services to patients by Physician Extender Personnel and
any other employee of Response.

         6.2.  Medical Practice.  The Provider shall use and occupy each Clinic
exclusively for the practice of medicine, and shall comply with all Applicable
Law and all standards of medical care.  It is expressly acknowledged by the
parties that the medical practice or practices conducted at a Clinic shall be
conducted solely by Physicians associated with the Provider, and no other
physician or medical practitioner shall be permitted to use or occupy a Clinic
without the prior written consent of Response and the Provider.

         6.3.  Employment of Physicians and Non-physician  Employees.  The
Provider shall have complete control of and responsibility for the hiring,
compensation, supervision, evaluation and termination of its Physicians and
Non-physician Employees, although at the request of the Provider, Response
shall consult with the Provider respecting such matters.  The Provider shall be
responsible for the payment of all Physician Expense and Non-physician Employee
Compensation now or hereafter applicable to Physicians and Non-physician
Employees; provided, however, that Response shall provide the payroll service
for computing, accounting for and disbursing or paying all salaries and
benefits of the Provider employees, all of whom may be paid out of the Provider
Operating Account.  With respect to Physicians, the Provider shall only employ
and contract with licensed Physicians meeting applicable credentialling
guidelines established by the Provider.

         To the extent permissible under the Employee Retirement and Income
Security Act of 1974, as amended ("ERISA"), the Internal Revenue Code of 1986,
as amended (the "Code"), and applicable Health Care Law and to the extent such
practice does not violate Applicable Law or jeopardize reimbursement for
medical related services provided by any person associated with a Clinic,
Response shall pay any overtime or other non-salary compensation of and shall
provide employee benefits to Non-physician Employees, notwithstanding their
employment by the Provider.  The cost of such items shall be Clinic Expense.
Response shall not provide any benefit to such persons to the extent the
Provider is required to provide same under ERISA, the Code or any other statute
or regulation.

         6.4.  Licensing Fees, Professional Dues and Education Expenses.
Except as provided in Section 5.5(g), the Provider and Physicians shall be
solely responsible for payment of the cost of professional licenses and dues
for membership in professional associations and continuing professional
education costs.  The Provider shall ensure that each of its Physicians and
Non-physician  Employees participates in such continuing medical education as
is necessary for such person to maintain current practical and academic
knowledge of the field of medicine and health care in which the Provider is
engaged.

         6.5.  Professional Insurance Eligibility.  The Provider shall be
primarily responsible, with assistance from Response, if requested, for
obtaining and retaining of professional liability insurance by assuring that
its Physicians are insurable, and participating in an on-going risk management
program.  Professional liability insurance shall be paid for by the Provider or
its Physicians and shall not be Clinic Expense.

         6.6.  Events Excusing Performance.  The Provider shall not be liable
to Response for failure to perform any of the services required herein in the
event of strikes, lock-outs, calamities, acts of God, unavailability of supplies
or other events over which the Provider has no control for so long as such
events continue, and for a reasonable period of time thereafter.
<PAGE>   17

         6.7.  Fees for Professional Services.  The Provider shall be solely
responsible for legal, accounting and other professional service fees incurred
by the Provider, except as set forth in Section 5.5(i) herein.

         6.8.  Peer Review.  The Provider agrees to cooperate with Response in
establishing a system of peer review as necessary to obtain provider contracts.
In connection therewith, the Provider agrees to assist in the formulation of
oncology and cancer care provider guidelines for each treatment or surgical
modality, and agrees to abide by said guidelines, and further agrees to submit
to periodic reviews by a third party to monitor compliance with said
guidelines.  The Provider acknowledges that the establishment of provider
guidelines may be necessary to obtain PPO, HMO, IPA and other similar provider
contracts, both private and government funded.  To the extent that said
provider guidelines must be filed or registered with any Third Party Payor, the
Provider agrees to cooperate with Response in making such filings or
registrations.  it is agreed and acknowledged that all such peer review
guidelines shall be established and monitored by medical personnel on the staff
of the Provider and other practices that are part of the peer review process,
and shall not be promulgated, established or enforced independently by
Response.  To the extent possible, all information obtained through the peer
review process shall remain confidential and the parties shall take all steps
reasonably necessary to assure that all privileges and immunities provided by
Applicable Law remain intact.

         6.9  Provider Employee Benefit Plans.

                 (a)  Effective as of the date of the closing under the
                 Acquisition Agreement, the Provider shall amend the
                 tax-qualified retirement plan(s) described on EXHIBIT 6.9(A)
                 (the "Provider Plan") to provide that employees of Response
                 who are classified as "leased employees" (as defined in Code
                 Section 414(n)) of the Provider shall be treated as the
                 Provider's employees for purposes described in Code Section
                 414(n)(3).  Not less often than annually, the Provider and
                 Response shall agree upon and identify in writing those
                 individuals to be classified as leased employees of the
                 Provider (the "Designated Leased Employees").  The Provider
                 and Response shall establish mutually agreeable procedures
                 with respect to the participation of Designated Leased
                 Employees in the Provider Plan.  Such procedures shall be
                 designed to avoid the tax disqualification of the Provider
                 Plan, similar plans of practices similarly situated,
                 (collectively, the "Plans").

                 (b)  If the Oversight Committee determines that the
                 relationship between Response and the Provider (and other
                 practices similarly situated) constitutes an "affiliated
                 service group" (as defined in Code Section 414(m)), Response
                 and the Provider shall take such actions as may be necessary
                 to avoid the tax disqualification of the Plans.  Such actions
                 may include the amendment, freeze, termination or merger of
                 the Provider Plan.

                 (c)  The Plans described on EXHIBIT 6.9(A) attached hereto are
                 approved by Response.  The Provider shall not enter into any
                 new "employee benefit plan" (as defined in Section 3(3) of the
                 Employment Retirement Income Security Act of 1974, as amended
                 ("ERISA") without the consent of Response (which will not be
                 unreasonably withheld).  In addition, the Provider shall not
                 offer any retirement benefits or make any material retirement
                 payments other than under the Provider Plan to any Member of
                 the Provider without the express written consent of Response
                 (which will not be unreasonably withheld).  Except as
                 otherwise required by law, the Provider shall not materially
                 amend, freeze, terminate or merge the Provider Plan without
                 the express written consent of Response (which will not be
                 unreasonably withheld).  In the event of either of the
                 foregoing, Response's consent shall not be withheld if such
                 action would not jeopardize the qualification of any of the
                 Plans.  The Provider agrees to make such changes to the
                 Provider Plan, including the amendment freeze, termination or
                 merger of the Provider Plan, as may be approved by the
                 Oversight Committee and Response but only if such
<PAGE>   18

                 changes are necessary to prevent the disqualification of any
                 of the Plans and do not have a material adverse impact on
                 Provider.

                 (d)  Expenses incurred in connection with the Provider Plan or
                 other Provider employee benefit plans, including, without
                 limitation, the compensation of counsel, accountants,
                 corporate trustees, and other agents shall be included in
                 Clinic Expenses.

                 (e)  The contribution and administration expenses for the
                 Designated Leased Employees shall be included in the
                 Provider's operating budget.  The Provider and Response shall
                 not make employee benefit plan contributions or payments to
                 the Provider for their respective employees in excess of such
                 budgeted amounts unless required by law or the terms of the
                 Provider Plan.  Response shall make contributions or payments
                 with respect to the Provider Plan or other Provider employee
                 benefit plans, as a Clinic Expense, on behalf of eligible
                 Designated Leased Employees, and other eligible Provider
                 employees.  In the event a Provider Plan or other Provider
                 employee benefit plan is terminated, Response shall be
                 responsible, as a Clinic Expense, for any funding liabilities
                 related to eligible Designated Leased Employees; provided,
                 however, Response shall only be responsible for the funding of
                 any liability accruing after the date of the Acquisition
                 Agreement.

                 (f)  Response shall have the sole and exclusive authority to
                 adopt, amend or terminate any employee benefit plan for the
                 benefit of its employees, regardless of whether such employees
                 are Designated Leased Employees, unless such actions would
                 require the amendment, freeze or termination of the Provider
                 Plan to avoid disqualification of the Provider Plan, in which
                 case any such action would be subject to the express prior
                 written consent of the Oversight Committee.  Response shall
                 have the sole and exclusive authority to appoint the trustee,
                 custodian and administrator of any such plan.

                 (g)  In the event that any "employee welfare benefit plan" (as
                 defined in ERISA Section 3(l)) maintained or sponsored by the
                 Provider must be amended, terminated, modified or changed as a
                 result of the Provider or Response being deemed to be a part
                 of an affiliated service group, the Oversight Committee will
                 replace such plan or plans with a plan or plans that provides
                 those benefits approved by the Oversight Committee.  It shall
                 be the goal of the Oversight Committee in such event to
                 provide substantially similar or comparable benefits if the
                 same can be provided at a substantially similar cost to the
                 replaced plan.

                                   ARTICLE 7.
           EMPLOYMENT AGREEMENTS, RESTRICTIVE COVENANTS AND REMEDIES

                 The parties recognize that the services to be provided by
Response shall be feasible only if the Provider operates an active medical
practice to which the Physicians associated with the Provider devote their full
time and attention.  To that end:

         7.1.  Employment Agreements with Physicians.  As a condition to
Response's continuing obligations hereunder, the Provider and each Physician
now or hereinafter employed thereby shall execute and deliver to each other an
employment contract substantially in the form set forth as Exhibit 6(a)(x) of
the Purchase Agreement.

         7.2.  Restrictive Covenants by Physicians.  The Provider shall obtain
in each Employment Agreement and use its best efforts to enforce (subject to
Response's obligations under Section 5.5 of this Agreement) formal agreements
from each Physician pursuant to which the Physician agrees not to engage in the
practice of oncology or hematology, including providing or supervising the
provision of
<PAGE>   19

chemotherapy, radiation treatment or other cancer therapies, within Knox County
in Tennessee (the "Practice Territory") during the term of the Employment
Agreement and for a period of five (5) years after any termination of
employment with the Provider.  Notwithstanding the foregoing, any such
restrictive covenant shall not restrict such Physician from (i) delivering
physician services that are unrelated to the fields of hematology or oncology,
including the practice of internal medicine, (ii) teaching hematology and/or
oncology or (iii) assuming directorships of hospices following termination of
any such employment relationship with the Provider.

         7.3.  Restrictive Covenants of Response.  During the term of this
Agreement, neither Response nor any Affiliate, officer, director or employee of
Response or any Affiliate shall, without the consent of the Provider, purchase
or otherwise acquire any oncology or hematology practice within the Practice
Territory or establish, operate or enter into a service agreement with, or
provide service similar to those provided under this Agreement to, any medical
group or physician engaged in the practice of oncology or hematology within the
Practice Territory.

         7.4.  Enforcement.  Response and the Provider acknowledge and agree
that since a remedy at law for any breach or attempted breach of the provisions
of this Article 7 shall be inadequate, either party shall be entitled to
specific performance and injunctive or other equitable relief in case of any
such breach or attempted breach, in addition to whatever other remedies may
exist by law.  All parties hereto also waive any requirement for the securing
or posting of any bond in connection with the obtaining of any such injunctive
or other equitable relief.  If any provision of Article 7 relating to the
restrictive period, scope of activity restricted and/or the territory described
therein shall be declared by a court of competent jurisdiction to exceed the
maximum time period, scope of activity restricted or geographical area such
court deems reasonable and enforceable under applicable law, the time period,
scope of activity restricted and/or area of restriction held reasonable and
enforceable by the court shall thereafter be the restrictive period, scope of
activity restricted and/or the territory applicable to the restrictive covenant
provisions in this Article 7.  The invalidity or non-enforceability of this
Article 7 in any respect shall not affect the validity or enforceability of the
remainder of this Article 7 or of any other provisions of this Agreement.


                                   ARTICLE 8.
                             FINANCIAL ARRANGEMENTS

         8.1.  Service Fees.  Subject to the terms of Section 5.11, in
consideration for its services hereunder, Response shall receive the Base
Service Fee and Performance Fee, computed pursuant to Schedule A hereto, as
compensation for its services hereunder, payable by means of the procedure set
forth in Section 8.2 below.  Notwithstanding the foregoing or any other
provision in this Service Agreement, in the event the sum of the Base Service
Fee, Non-physician Employee Compensation and Practice Retainage shall exceed
the aggregate Practice Revenue of the Provider, then (i) first, the Fixed
Portion of Base Service Fee shall be reduced by the amount of such excess, and
(ii) to the extent such excess is greater than the Fixed Portion, such
remaining excess will be reimbursed by Response to the Provider no later than
the last day of the month immediately succeeding the month such excess arose.

         8.2.  Base Fee.  The Clinic Expense Portion of the Base Service Fee
shall be payable by the Provider to Response out of the Provider Operating
Account as Clinic Expenses are incurred by Response, subject to ordinary,
reasonable and customary payment terms on invoices for goods and services, and
subject to Section 5.11 and the adjustments as set forth in Section 8.1 above.
The Fixed Portion of the Base Service Fee shall be payable by the Provider to
Response out of the Provider Operating Account on a monthly basis, subject to
Section 5.11 and reduction as set forth in Section 8.1 above.  The Performance
Fee will be computed as of the end of each calendar year based on amounts
recorded during the calendar year.
<PAGE>   20

                                   ARTICLE 9.
                                    RECORDS

         9.1.  Patient Records.  Upon termination of this Agreement, the
Provider shall retain all patient medical records maintained by the Provider or
Response in the name of the Provider.  Response shall, at its option, and if
allowed under Applicable Law be entitled to have reasonable access during
normal business hours to the Provider's patient medical records applicable to
the period of Response's performance under this Agreement.  Moreover, the
Provider shall, at its option, be entitled to retain copies of financial and
accounting records relating to all services performed by the Provider or
Response under this Agreement.  All parties agree to maintain the
confidentiality of patient identifying information and not to disclose such
information except as may be required or permitted by Applicable Law.

         9.2.  Records Owned by Response.  All records relating in any way to
the operation of a Clinic which are not the property of the Provider under the
provisions of Section 9.1 above, shall at all times be the property of
Response.

         9.3.  Access to Records.  During the term of this Agreement and
thereafter, the Provider or its designee shall have reasonable access during
normal business hours in Knoxville, Tennessee to the Provider's and Response's
financial and accounting records, including, but not limited to, records of
collections, expenses and disbursements, as kept by Response in performing
Response's obligations under this Agreement, and the Provider may copy any and
or all such records.

         9.4.  Government Access to Records.  To the extent required by
Section 1861(v)(1)(I) of the Social Security Act, each party shall, upon proper
request, allow the United States Department of Health and Human Services, the
Comptroller General of the United States, and their duly authorized
representatives access to this Agreement and to all books, documents, and
records necessary to verify the nature and extent of the costs of services
provided by either party under this Agreement, at any time during the term of
this Agreement and for an additional period of four (4) years following the
last date services are furnished under this Agreement.  If either party carries
out any of its duties under this Agreement through an agreement between it and
an individual or organization related to it or through a subcontract with an
unrelated party, that party to this Agreement shall require that a clause be
included in such agreement (the value of which is in excess of $10,000.00) to
the effect that until the expiration of four (4) years after the furnishing of
services pursuant to such agreement, the related organization shall make
available, upon request by the United States Department of Health and Human
Services, the Comptroller General of the United States, or any of their duly
authorized representatives, all agreements, books, documents, and records of
such related organization that are necessary to verify the nature and extent of
the costs of services provided under that agreement.

                                  ARTICLE 10.
                            INSURANCE AND INDEMNITY

         10.1.  Insurance to be Maintained by the Provider.  Throughout the
term of this Agreement, the Provider shall maintain comprehensive professional
liability insurance with limits of not less than $500,000 per claim and with
aggregate policy limits of not less than $1,000,000 per physician and a
separate limit for the Provider.  The Provider shall be responsible for all
liabilities in excess of the limits of such policies.  Response shall have the
option, with Oversight Committee approval, of providing such professional
liability insurance through an alternative program, provided such program meets
the requirements of the Insurance Commissioner of the State of Tennessee.
Response shall reimburse the Provider for any unearned professional liability
insurance premiums paid by the Provider to the extent not reimbursed or
reimbursable by the Provider's insurance carrier if the Provider's existing
professional liability insurance program is cancelled and replaced by a
comparable professional liability insurance program initiated by Response.
<PAGE>   21

         10.2.  Insurance to be Maintained by Response.  Throughout the term of
this Agreement, Response shall provide and/or maintain comprehensive
professional liability insurance for all Non-physician  Employees who are not
physicians and all professional employees of Response, the cost of which shall
be a Clinic Expense, with limits as determined reasonable by Response in its
national program, and comprehensive general liability and property insurance
covering each Clinic premises and operations.

         10.3.  Additional Insureds.  The Provider and Response each agrees to
use its best efforts to have the other named as an additional insured on the
their respective professional liability insurance programs.

         10.4.  Indemnification Matters Involving Third Parties.  The Provider
and Response ("Indemnitor") shall indemnify, hold harmless and defend the other
("Indemnitee") from and against any and all liability, loss, damage, claim,
causes of action, and expenses (including reasonable attorneys' fees, except to
the extent limited below), whether or not covered by insurance ("Adverse
Consequences"), caused or asserted to have been caused, directly or indirectly,
by or as a result of the acts (intentional or negligent) or omissions by, in
the case of the Provider, by any Physician Member or other person acting under
the supervision and control thereof, or, in the case of Response, by any
employee, agent, officer, director or shareholder thereof who is not acting
under the supervision and control of a Physician Member of the Provider.

                 (a) If any third party shall notify an Indemnitee with respect
                 to any matter (a "Third Party Claim") which may give rise to a
                 claim for indemnification under this Section 10.4, then the
                 Indemnitee shall promptly notify the Indemnitor in writing;
                 provided, however, that no delay on the part of the Indemnitee
                 in notifying the Indemnitor shall relieve the Indemnitor from
                 any obligation hereunder unless (and then solely to the
                 extent) the Indemnitor is prejudiced by such delay.

                 (b) The Indemnitor will have the right to defend the
                 Indemnitee against the Third Party Claim with counsel of its
                 choice reasonably satisfactory to the Indemnitee so long as
                 (A) the Indemnitor notifies the Indemnitee in writing within
                 15 days after the Indemnitee has given notice of the Third
                 Party Claim that the Indemnitor will indemnify the Indemnitee
                 in accordance with this Article 10, (B) the Indemnitor
                 provides the Indemnitee with evidence acceptable to the
                 Indemnitee that the Indemnitor will have the financial
                 resources to defend against the Third Party Claim and fulfill
                 its indemnification obligations hereunder, (C) the Third Party
                 Claim involves only money damages and does not seek an
                 injunction or other equitable relief, (D) settlement of, or an
                 adverse judgment with respect to, the Third Party Claim is
                 not, in the good faith judgment of the Indemnitee, likely to
                 establish a precedential custom or practice adverse to the
                 continuing business interests of the Indemnitee, and (E) the
                 Indemnitor conducts the defense of the Third Party Claim
                 actively and diligently.

                 (c) So long as the Indemnitor is conducting the defense of the
                 Third Party Claim in accordance with Section 10.4(b) above,
                 (A) the Indemnitee may retain separate co-counsel at its sole
                 cost and expense and participate in the defense of the Third
                 Party Claim, (B) the Indemnitee will not consent to the entry
                 of any judgment or enter into any settlement with respect to
                 the Third Party Claim without the prior written consent of the
                 Indemnitor (not to be withheld unreasonably), and (C) the
                 Indemnitor will not consent to the entry of any judgment or
                 enter into any settlement with respect to the Third Party
                 Claim without the prior written consent of the Indemnitee (not
                 to be unreasonably withheld).
<PAGE>   22

                 (d) In the event any of the conditions in Section 10.4(b)
                 above is or becomes unsatisfied, however, (A) the Indemnitee
                 may defend against, and consent to the entry of any judgment
                 or enter into any settlement with respect to, the Third Party
                 Claim in any manner it may deem appropriate (and the
                 Indemnitee need not consult with, or obtain any consent from,
                 the Indemnitor in connection  therewith), (B) the Indemnitor
                 will reimburse the Indemnitee promptly and periodically for
                 the costs of defending against the Third Party Claim
                 (including attorneys' fees and expenses), and (C) the
                 Indemnitor will remain responsible for any Adverse
                 Consequences the Indemnitee may suffer resulting from, arising
                 out of, relating to, in the nature of, or caused by the Third
                 Party Claim to the fullest extent provided in this Section 
                 10.4.

         10.5.  Determination of Adverse Consequences.  The parties hereto
shall take into account the time cost of money (using the Applicable Rate as
the discount rate) in determining Adverse Consequences for purposes of this
Section 10.

         10.6.  Other Indemnification Provisions.  The foregoing
indemnification provisions are in addition to, and not in derogation of, any
statutory, equitable, or common law remedy any party may have for breach of
representation, warranty, or covenant.

                                  ARTICLE 11.
                              TERM AND TERMINATION

         11.1.  Term of Agreement.  This Service Agreement shall be effective
as of the closing of the Purchase Agreement and shall expire on April 30, 2035,
unless earlier terminated pursuant to the terms hereof.

         11.2.  Extended Term.  Unless earlier terminated as provided for in
this Agreement, the term of this Agreement shall be automatically extended for
additional terms of five (5) years each, unless either party delivers to the
other party, not less than one hundred eighty (180) days prior to the
expiration of the preceding term, written notice of such party's intention not
to extend the term of this Agreement.

         11.3.  Response Event of Default.  The occurrence of any of the
following events shall constitute a default by Response (a "Response Event of
Default") under this Agreement, giving the Provider the right to the remedies
set forth in Section 11.5 below:

                 (a)  the filing by Response of a petition in voluntary
                 bankruptcy or an assignment by Response for the benefit of
                 creditors, or upon other action taken or suffered, voluntarily
                 or involuntarily, under any federal or state law for the
                 benefit of debtors by Response, except for the filing of a
                 petition in involuntary bankruptcy against Response which is
                 dismissed within sixty (60) days thereafter.

                 (b)  any material default by Response in the performance of
                 any of its duties or obligations under this Agreement or
                 breach of its representations and warranties as set forth in
                 Article 14, and such default or breach shall continue for a
                 period of sixty (60) days (fifteen (15) days in the case of
                 Response's failure to provide required advances under the
                 Receivables Line) after written notice thereof has been given
                 to Response by the Provider.

                 (c)  in the event Response shall, intentionally or in bad
                 faith, misapply funds or assets of the Provider or commit a
                 similar act which cause material harm to the Provider.

                 (d)  in the event Response shall default in the payment of any
                 promissory note payable by Response to the Provider.
<PAGE>   23

         11.4.  Provider Event of Default.  The occurrence of any of the
following events shall constitute a default by the Provider (an "Provider Event
of Default") under this Agreement, giving Response the right to the remedies
set forth in Section 11.6 below:

                 (a)  the filing by the Provider of a petition in voluntary
                 bankruptcy or an assignment by the Provider for the benefit of
                 creditors, or upon other action taken or suffered, voluntarily
                 or involuntarily, under any federal or state law for the
                 benefit of debtors by the Provider, except for the filing of a
                 petition in involuntary bankruptcy against the Provider which
                 is dismissed within sixty (60) days thereafter; provided,
                 however, that no Provider Event of Default shall be deemed to
                 exist if, within sixty (60) days following the occurrence of
                 the enumerated event, the Provider and/or the Physicians who
                 are then Physician Members of the Provider lawfully reorganize
                 the Provider or lawfully transfer the practice theretofore
                 conducted by the Provider to a new entity which assumes, with
                 the reasonable consent of Response, all of the obligations of
                 the Provider hereunder (together with a written reaffirmation
                 by the persons who would be Remaining Physician Members of the
                 Provider at that time of their personal liability under
                 Section 11.6), and the successor practice (or reorganized
                 Provider, as the case may be) then continues the practice
                 theretofore conducted by the Provider in substantially the
                 same manner as it had theretofore been conducted under this
                 Agreement.

                 (b)  any material default by the Provider in the performance
                 of any of its duties or obligations under this Agreement or
                 breach of its representations and warranties as set forth in
                 Article 13, and such default or breach shall continue for a
                 period of sixty (60) days after written notice thereof has
                 been given to the Provider by Response.

                 (c)  the final determination of termination or suspension of
                 the Provider's Medicare or Medicaid Provider Number primarily
                 for reasons not arising out of any action or inaction by
                 Response in performing its obligations under this Agreement,
                 and such termination or suspension shall continue for sixty
                 (60) days.

         11.5.  Remedies upon Response Event of Default.  Upon the occurrence
of a Response Event of Default, the Provider shall have the right to terminate
this Agreement by written notice to Response without any further obligation to
Response for Service Fees after the giving of such notice.  In such event the
Provider shall have the option to purchase from Response, and upon proper
exercise of such option by the Provider in the manner hereinbelow provided,
Response shall sell to the Provider, all assets and properties, tangible and
intangible (except that intangible assets shall not include any intangible
asset related to this Service Agreement), owned by Response and used by the
Provider in its medical practice ("Practice Assets") for a price, payable in
cash, equal to the fair market value of the Practice Assets.  The Provider
shall exercise such option by giving written notice to Response within sixty
(60) days after the occurrence of the Response Event of Default.  Upon delivery
of such exercise, Response and the Provider shall negotiate in good faith the
fair market value as of the date of the Response Event of Default of the assets
to be acquired.  In the event that, after at least fifteen (15) days of good
faith negotiation, Response and the Provider shall not have agreed upon the
fair market value of the Practice Assets, each party shall select an appraiser
who shall provide an evaluation report with respect to the fair market value of
the Practice Assets.  If the valuations of the appraisers are within $25,000.00
of each other, then the lowest appraisal shall be deemed the fair market value
of the Practice Assets, and the Provider shall purchase the Practice Assets for
such value.  If the valuation of the appraisers are more than $25,000.00
different, then the two appraisers shall agree upon a third appraiser, and the
average value set forth in the three appraisals shall be deemed the fair market
value of the Practice Assets, and the Provider shall purchase the Practice
Assets for such value.
<PAGE>   24

                 11.6.  Remedies upon Provider Event of Default.  Upon the
occurrence of a Provider Event of Default, Response shall have the right to
terminate this Agreement by written notice to the Provider, and the Provider
shall have no further obligation to Response for Service Fees after the date
such notice is received.  In such event, the Provider shall be obligated to pay
to Response the Liquidated Damages Amount in complete satisfaction of any and
all damages suffered by Response hereunder.  Such Liquidated Damages Amount
shall be payable by the Provider in cash within sixty (60) days after
occurrence of the Provider Event of Default.  Each Member hereby severally, and
not jointly, guarantees the foregoing obligation of the Provider and agrees to
pay to Response his pro rata share of the Liquidated Damages Amount provided
that and to the extent he is a Remaining Physician Member for purposes of this
Agreement, with the pro rata share being equal to the portion of the Liquidated
Damages Amount not paid by the Provider divided by the number of Remaining
Physician Members as of the date of occurrence of a Provider Event of Default.
Moreover, in such event the Provider shall have the option to purchase from
Response, and upon proper exercise of such option by the Provider in the manner
hereinbelow provided, Response shall sell to the Provider, all Practice Assets
for a price, payable in cash, equal to the fair market value of the Practice
Assets as of the date of the Provider Event of Default.  The Provider shall
exercise such option by giving written notice to Response within sixty (60)
days after the occurrence of the Response Event of Default.  Upon delivery of
such exercise, Response and the Provider shall negotiate in good faith the fair
market value of the assets to be acquired.  In the event that, after at least
fifteen (15) days of good faith negotiation, Response and the Provider shall
not have agreed upon the fair market value of the Practice Assets, each party
shall select an appraiser who shall provide an evaluation report with respect
to the fair market alue of the Practice Assets.  If the valuations of the
appraisers are within $25,000.00 of each other, then the lowest appraisal shall
be deemed the fair market value of the Practice Assets, and the Provider shall
purchase the Practice Assets for such value.  If the valuation of the
appraisers are more than $25,000.00 different, then the two appraisers shall
agree upon a third appraiser, and the average value set forth in the three
appraisals shall be deemed the fair market value of the Practice Assets, and
the Provider shall purchase the Practice Assets for such value.

         11.7.  Closing of Repurchase by the Provider and Effective Date of
Termination.  The Provider shall pay cash for Practice Assets repurchased
hereunder.  The amount of the purchase price shall be reduced by the amount of
debt and liabilities of Response assumed by the Provider and shall also be
reduced by any payment Response has failed to make under this Agreement,
provided that such payments or obligations are not otherwise accounted for in
the liabilities assumed by the Provider in connection with the repurchase
described herein.  The closing date for the repurchase shall be determined by
the Provider, but shall in no event occur later than 180 days from the date of
the notice of termination.  In the event of exercise of such option, each party
shall use its best efforts to obtain such consents and authorizations to such
transaction as may be required by Applicable Law or otherwise.  In such event,
Response shall execute and deliver to the Provider such assignments to leases
and other contracts and such bills of sale and other transfer or closing
documents necessary to effect such transaction.  The Provider shall execute and
deliver to Response such officers' certificates, assumption agreements and
other closing documents necessary to close such transaction.  Between the date
of termination and the earlier to occur of closing the repurchase as
hereinabove described or the termination (without exercise) of any repurchase
option, the Provider shall be entitled to use all Practice Assets, and Response
hereby grants the Provider a license to use the Practice Assets in such event.
In consideration of the foregoing license, the Provider will pay to Response an
amount equal to any rental payments by Response to any third party vendor in
respect of all Practice Assets.

                                   ARTICLE 12
                         DAMAGE AND LOSS; CONDEMNATION

         12.1.  Use of Insurance Proceeds.  All insurance or condemnation
proceeds payable by reason of any physical loss of any of the improvements
comprising the facilities or the furniture, fixtures and equipment used by the
Clinics, shall be available for the reconstruction, repair or replacement, as 
the
<PAGE>   25

case may be, of any damage, destruction or loss.  The Oversight Committee, in
consultation with the Provider, shall review and approve such reconstruction,
repair or replacement.

         12.2.  Temporary Space.  In the event of substantial damage to or the
condemnation of a significant portion of the facilities, Response shall use its
best efforts to provide temporary facilities until such time as the facilities
can be restored or replaced.

                                   ARTICLE 13
                 REPRESENTATIONS AND WARRANTIES OF THE PROVIDER

         The Provider represents, warrants, covenants and agrees with Response
that:

         13.1.  Validity.  The Provider is a professional association duly
organized, validly existing and in good standing under the laws of the State of
Tennessee.  The Provider has the full power and authority to own its property,
to carry on its business as presently being conducted, to enter into this
Agreement, and to consummate the transactions contemplated hereby.

         13.2.  Litigation.  Except as disclosed in writing to Response prior
to the effective date hereof, there is no suit, action, proceeding at law or in
equity, arbitration, administrative proceeding or other proceeding  pending, or
threatened against, or affecting the Provider or the Group, or any of the
assets to be acquired from the Group pursuant to the Purchase Agreement, or to
the best of the Provider's knowledge, any hematology or oncology provider or
other health care professional associated with or employed by the Provider as
pertains to any claim involving the providing of health care related services,
and to the best of the Provider's knowledge there is no basis for any of the
foregoing.

         13.3.  Permits.  The Provider and all physicians and other health care
professionals associated with or employed by the Provider have all permits and
licenses and other Necessary Authorizations required by all Applicable Laws,
except where failure to secure such licenses, permits and other Necessary
Authorizations does not have a material adverse effect; have made all
regulatory filings necessary for the conduct of the Provider's business; and
are not in violation of any of said permitting or licensing requirements.

         13.4.  Authority.  The execution of this Agreement and the
consummation of the transactions contemplated hereby have been duly authorized
by all necessary action, and this Agreement is a valid and binding Agreement of
the Provider, enforceable in accordance with its terms.  The Provider has
obtained all third-party consents necessary to enter into and consummate the
transaction contemplated by this Agreement.  Neither the execution and delivery
of this Agreement, the consummation of the transactions contemplated hereby,
nor compliance by the Provider with any of the provisions hereof, will:

                 (a)  violate or conflict with, or result in a breach of any
provision of, or constitute a default (or an event which, with notice or lapse
of time or both, would constitute a default) under, or result in the
termination of, or accelerate the performance required by, or result in the
creation of, any lien, security interest, charge or encumbrance upon any of the
assets of the Group to be acquired pursuant to the Purchase Agreement, the
Provider's charter or bylaws or any of the terms, conditions or provisions of
any note, bond, mortgage, indenture, deed of trust, license, agreement or other
instrument or obligation to which the Provider is a party, or by which either
the Provider or any of the assets to be conveyed hereunder is bound; or

                 (b)  violate any order, writ, injunction, decree, statute,
rule or regulation applicable either to the Provider or any of the assets to be
conveyed hereunder.

         13.5.  Compliance with Applicable Laws.  To the best of the Provider's
knowledge and belief, the Provider has operated in compliance with all federal,
state, county and municipal laws, ordinances and
<PAGE>   26

regulations applicable thereto and neither the Provider nor any physician or
other Person associated with or employed by the Provider has received payment
or any remuneration whatsoever to induce or encourage the referral of patients
or the purchase of goods and/or services as prohibited under 42 U.S.C. Section
1320a-7b(b), or otherwise perpetrated any Medicare or Medicaid fraud or abuse,
nor has any fraud or abuse been alleged within the last five (5) years by any
Governmental Authority, a carrier or a Third Party Payor.

         13.6.  Health Care Compliance.  The Provider and each Physician
associated therewith is presently participating in or otherwise authorized to
receive reimbursement from or is a party to Medicare, Medicaid, and other
Third-Party Payor Programs.  All necessary certifications and contracts
required for participation in such programs are in full force and effect and
have not been amended or otherwise modified, rescinded, revoked or assigned as
of the date hereof, and no condition exists or event has occurred which in
itself or with the giving of notice or the lapse of time or both would result
in the suspension, revocation, impairment, forfeiture or non-renewal of any
such Third Party Payor Program.  The Provider and each Physician associated
therewith is in full compliance with the requirements of all such Third Party
Payor Programs applicable thereto.

         13.7.  Fraud and Abuse.  The Provider and persons and entities
providing professional services for the Provider, have not, to the knowledge of
the Provider, after due inquiry, engaged in any activities which are prohibited
by or are in violation of the rules, regulations, policies, contracts or laws
pertaining to any Third Party Payor Program, or which are prohibited by rules
of professional conduct ("Governmental Rules and Regulations"), including but
not limited to the following:  (a) knowingly and willfully making or causing to
be made a false statement or representation of a material fact in any
application for any benefit or payment; (b) knowingly and willfully making or
causing to be made any false statement or representation of a material fact for
use in determining rights to any benefit or payment; (c) failing to disclose
knowledge by a claimant of the occurrence of any event affecting the initial or
continued right to any benefit or payment on the Provider's own behalf or on
behalf of another, with intent to fraudulently secure such benefit or payment;
or (d) knowingly and willfully soliciting or receiving any remuneration
(including any kickback, bribe, or rebate), directly or indirectly, overtly or
covertly, in cash or in kind or offering to pay or receive such remuneration
(i) in return for referring an individual to a person for the furnishing or
arranging for the furnishing or any item or service for which payment may be
made in whole or in part by Medicare or Medicaid, or (ii) in return for
purchasing, leasing, or ordering or arranging for or recommending purchasing,
leasing, or ordering any good, facility, service or item for which payment may
be made in whole or in part by Medicare or Medicaid.

         13.8.  Provider Compliance.  The Provider has all licenses necessary
to operate the Clinic in accordance with the requirements of all Applicable
Laws and has all Necessary Authorizations for the use and operation, all of
which are in full force and effect.  There are no outstanding notices of
deficiencies relating to the Provider issued by any Governmental Authority or
Third Party Payor requiring conformity or compliance with any Applicable Law or
condition for participation of such Governmental Authority or Third Party
Payor, and after reasonable and independent inquiry and due diligence and
investigation, the Provider has neither received notice nor has any knowledge
or reason to believe that such Necessary Authorizations may be revoked or not
renewed in the ordinary course.

         13.9.  Rates and Reimbursement Policies.  Except as previously
disclosed in writing to Response, the Provider does not have any rate appeal
currently pending before any Governmental Authority or any administrator of any
Third Party Payor Program.

         13.10.  Full Disclosure.  When considered in the context of all
information contained herein, no representation or warranty made by the
Provider in this Agreement contains or will contain any untrue statement of a
material fact.
<PAGE>   27

         13.11.  Exhibits.  All the facts recited in Exhibits annexed hereby
(as updated as of the effective date hereof) shall be deemed to be
representations of fact by the Provider as though recited in this Article 13.

                                   ARTICLE 14
                   REPRESENTATIONS AND WARRANTIES OF RESPONSE

         Response represents, warrants, covenants and agrees with the Provider
as follows:

         14.1.  Organization.  Response is a corporation duly organized,
validly existing and in good standing under the laws of the State of Tennessee.
Response has the full power to own its property, to carry on its business as
presently conducted, to enter into this Agreement and to consummate the
transactions contemplated hereby.

         14.2.  Authority.  The execution of this Agreement and the
consummation of the transactions contemplated hereby have been duly authorized
by all necessary action, and this Agreement is a valid and binding Agreement of
Response enforceable in accordance with its terms.  Response has taken all
necessary action to authorize the execution, delivery and performance of this
Agreement, as well as the consummation of the transactions contemplated hereby.
The execution and delivery of this Agreement do not, and the consummation of
the transactions contemplated hereby will not, violate any provisions of the
charter or the bylaws of Response or any indenture, mortgage, deed of trust,
lien, lease, agreement, arrangement, contract, instrument, license, order,
judgment or decree or result in the acceleration of any obligation thereunder
to which Response is a party or by which it is bound.

         14.3.  Litigation.  There is no suit, action, proceeding at law or in
equity, arbitration, administrative proceeding or other proceeding pending or,
to the best of Response's knowledge, threatened against Response that, if
successful, would have a material adverse effect on Response, and, to the best
of Response's knowledge, there is no basis for the foregoing.

         14.4.  Permits.  Response has all permits and licenses and other
Necessary Authorizations required by all Applicable Laws, except where failure
to secure such licenses, permits and other Necessary Authorizations does not
have a material adverse effect; have made all regulatory filings necessary for
the conduct of Response's business; and are not in violation of any of said
permitting or licensing requirements.

         14.5.  Compliance with Applicable Laws.  To the best of Response's
knowledge and belief, Response has operated in compliance with all federal,
state, county and municipal laws, ordinances and regulations applicable thereto
and neither Response nor any other Person associated with or employed by
Response has received payment or any remuneration whatsoever to induce or
encourage the referral of patients or the purchase of goods and/or services as
prohibited under 42 U.S.C. Section 1320a-7b(b), or otherwise perpetrated any
Medicare or Medicaid fraud or abuse, nor has any fraud or abuse been alleged
within the last five (5) years by any Governmental Authority, a carrier or a
Third Party Payor.

         14.6.  Fraud and Abuse.  Response and persons and entities providing
professional services for Response, have not, to the knowledge of Response,
after due inquiry, engaged in any activities which are prohibited by or are in
violation of the rules, regulations, policies, contracts or laws pertaining to
any Third Party Payor Program, or which are prohibited by rules of professional
conduct ("Governmental Rules and Regulations"), including but not limited to
the following:  (a) knowingly and willfully making or causing to be made a
false statement or representation of a material fact in any application for any
benefit or payment; (b) knowingly and willfully making or causing to be made
any false statement or representation of a material fact for use in determining
rights to any benefit or payment; (c) failing to disclose knowledge by a
claimant of the occurrence of any event affecting the initial or continued
right to any benefit or payment on Response's own behalf or on behalf of
another, with intent to fraudulently secure such benefit or payment; or (d)
knowingly and willfully soliciting or receiving any remuneration
<PAGE>   28

(including any kickback, bribe, or rebate), directly or indirectly, overtly or
covertly, in cash or in kind or offering to pay or receive such remuneration
(i) in return for referring an individual to a person for the furnishing or
arranging for the furnishing or any item or service for which payment may be
made in whole or in part by Medicare or Medicaid, or (ii) in return for
purchasing, leasing, or ordering or arranging for or recommending purchasing,
leasing, or ordering any good, facility, service or item for which payment may
be made in whole or in part by Medicare or Medicaid.

         14.7.  Full Disclosure.  When considered in the context of all
information contained herein, no representation or warranty made by the
Response in this Agreement contains or will contain any untrue statement of a
material fact.


                                   ARTICLE 15
                           COVENANTS OF THE PROVIDER

         15.1.  Merger, Consolidation and Other Arrangements.  The Provider
shall not incorporate, merge or consolidate with any other entity or individual
or liquidate or practice at any location other than the Clinics or dissolve or
wind-up the Provider's affairs or enter into any partnerships, joint ventures
or sale-leaseback transactions or purchase or otherwise acquire (in one or a
series of related transactions) any part of the property or assets (other than
purchases or other acquisitions of inventory, materials and equipment in the
ordinary course of business) of any other person or entity without first
obtaining the prior written consent of Response; provided, however, that no
such consent shall be required in respect of any incorporation, merger,
consolidation, partnership, joint venture or acquisition transaction that (i)
results in the continued, unimpaired operation of the Clinics; and (ii) results
in the Physician Members maintaining at least a fifty percent (50%) voting and
equity interest in the Clinics.  The Provider acknowledges and agrees that such
consent may be withheld if Response and the Provider cannot mutually agree upon
the terms and conditions of a new Service Agreement with the Provider.

         15.2.  Necessary Authorizations/Assignment of Licenses and Permits.
The Provider shall maintain all licenses, permits, certifications, or other
Necessary Authorizations and shall not assign or transfer any interest in any
license, permit, certificate or other Necessary Authorization granted to it by
any Governmental Authority, nor shall the Provider assign, transfer, or remove
or permit any other individual or entity to assign, transfer or remove any
records of the Provider, including without limitation, patient records, medical
and clinical records (except for removal of such patient records as directed in
writing by the patients owning such records or as otherwise required under any
Applicable Law).

         15.3.  Transaction with Affiliates.  The Provider shall not enter into
any transaction or series of transactions, whether or not related or in the
ordinary course of business, with any Affiliate of Response, other than on
terms and conditions substantially as favorable to the Provider as would be
obtainable by the Provider at the time in a comparable arms-length transaction
with a person not an Affiliate of Response.

         15.4.  Compliance with All Laws.  The Provider shall comply with all
laws and regulations relating to the Provider's practice and the operation of
any cancer care facility, including, but not limited to, all state, federal and
local laws relating to the acquisition or operation of a health care practice.
Furthermore, the Provider shall not violate any Applicable Laws.

         15.5.  Third Party Payor Programs.  The Provider shall maintain the
Provider's compliance with the requirements of all Third Party Payor Programs
in which the Provider is currently participating or authorized to participate.

         15.6.  Change in Business or Credit and Collection Policy.  The
Provider shall not make any change in the character of the Provider's business
or in the credit and collection policy, which change
<PAGE>   29

would, in either case, impair the collectibility of any Accounts Receivable or
otherwise modify, amend or extend the terms of any such account other than in
the ordinary course of business.

         15.7.  Security Interest.  The Provider shall, effective as of the
date hereof, be deemed to have granted (and the Provider does hereby grant) to
Response a first priority security interest in and to any and all of the
Accounts Receivable (except Governmental Receivables) and the proceeds thereof
(including the proceeds from the collection of Governmental Receivables after
such proceeds shall have been deposited into the Provider Operating Account) to
secure the repayment of all amounts advanced to the Provider under the
Receivables Line and all accrued interest thereon, and this Agreement shall be
deemed to be a security agreement.  Upon a default by the Provider in the
payment of amounts due under the Receivables Line, Response may at its option
exercise from time to time any and all rights and remedies available to it
under the UCC or otherwise.  The Provider represents and warrants that the
location of the Provider's principal place of business, and all locations where
the Provider maintains records with respect to its Accounts Receivables are set
forth under its name in Section 16.5 hereof.  The Provider agrees to notify
Response in writing thirty (30) days prior to any change in any such location.
The exact name of the Provider is as set forth at the beginning of this
Agreement.  The Provider is a new limited liability company, and the medical
practice conducted by the Provider was formerly conducted under the name
"Knoxville Hematology & Oncology Associates," a Tennessee general partnership.
The Provider shall notify Response in writing thirty (30) days prior to any
change in any such name.

         15.8.  Representations and Warranties.  The Provider agrees to notify
Response in the event that any representation or warranty contained in Article
13 of this Agreement becomes untrue in any material respect.

         15.9.  Additional Physician Members.  The Provider shall, as a
condition to permitting any physician from becoming a Physician Member after
the date hereof, obtain the signature of each such physician to a counterpart
amendment hereto, and, upon the obtaining of such signature, this Agreement
shall be deemed amended by adding as a party hereto the Physician Member who
shall sign such counterpart.

                                  ARTICLE 16.
                               GENERAL PROVISIONS

         16.1.  Assignment.  Response shall have the right to assign its rights
hereunder to any person, firm or corporation under common control with Response
and to any lending institution, for security purposes or as collateral, from
which Response obtains financing.  Except as set forth above, neither Response
nor the Provider shall have the right to assign their respective rights and
obligations hereunder without the written consent of the other party.

         16.2.  No Practice of Medicine.  The parties acknowledge that Response
is not authorized or qualified to engage in any activity which may be construed
or deemed to constitute the practice of medicine.  To the extent any act or
service required of Response in this Agreement should be construed or deemed by
any Governmental Authority or court to constitute the practice of medicine, the
performance of said act or service by Response shall be deemed waived and
forever unenforceable.

         16.3.  Whole Agreement; Modification.  This Agreement supersedes all
prior agreements between the parties, and there are no other agreements or
understandings, written or oral, between the parties regarding this Agreement,
the Exhibits and the Schedules, other than as set forth herein.  This Agreement
shall not be modified or amended except by a written document executed by both
parties to this Agreement, and such written modification(s) shall be attached
hereto.
<PAGE>   30

         16.4.  Arbitration of Disputes; Legal Fees.  Any dispute arising under
this Service Agreement shall be submitted by the parties to binding arbitration
pursuant to the Tennessee Uniform Arbitration Act, with any such arbitration
proceeding being conducted in Knoxville, Tennessee in accordance with the rules
of the American Arbitration Association.  Any arbitration panel presiding over
any arbitration proceeding hereunder is hereby empowered to render a decision
in respect of such dispute, to award costs and expenses (including reasonable
attorney fees) as it shall deem equitable and to enter its award in any court
of competent jurisdiction.

         16.5.  Notices.  All notices required or permitted by this Agreement
shall be in writing and shall be addressed as follows:

                    To Response:      Response Oncology, Inc.
                                      1775 Moriah Woods Blvd.
                                      Memphis, Tennessee  38117
                                      Attn:  Daryl P. Johnson, CFO

                    With copies to:   John A. Good, Esq.
                                      Executive Vice President & General Counsel
                                      Response Oncology, Inc.
                                      1775 Moriah Woods Blvd.
                                      Memphis, Tennessee 38117

                    To Provider:      Knoxville Hematology
                                      Oncology Associates, P.C.
                                      1114 Weisgarber Road, #E
                                      Knoxville, Tennessee
                                      37909-2648

                    With copies to:   James W. Parris, Esq.
                                      Bernstein, Stair & McAdams
                                      530 South Gay Street, Suite 600
                                      Knoxville, Tennessee  38902

or to such other addresses as either party shall notify the other.

         16.6.  Binding on Successors.  Subject to Section 16.1, this Agreement
shall be binding upon the parties hereto, and their successors, assigns, heirs
and beneficiaries.

         16.7.  Waiver of Provisions.  Any waiver of any terms and conditions
hereof must be in writing, and signed by the parties hereto.  The waiver of any
of the terms and conditions of this Agreement shall not be construed as a
waiver of any other terms and conditions hereof.

         16.8.  Governing Law.  The validity, interpretation and performance of
this Agreement shall be governed by and construed in accordance with the laws
of the State of Tennessee.  The parties acknowledge that Response is not
authorized or qualified to engage in any activity which may be construed or
deemed to constitute the practice of medicine.  To the extent any act or
service required of Response in this Agreement should be construed or deemed,
by any governmental authority, agency or court to constitute the practice of
medicine, the performance of said act or service by Response shall be deemed
waived and forever unenforceable.

         16.9.  Severability.  The provisions of this Agreement shall be deemed
severable and if any portion shall be held invalid, illegal or unenforceable
for any reason, the remainder of this Agreement shall be effective and binding
upon the parties.
<PAGE>   31

         16.10.  Additional Documents.  Each of the parties hereto agrees to
execute any document or documents that may be requested from time to time by
the other party to implement or complete such party's obligations pursuant to
this Agreement.

         16.11.  Time is of the Essence.  Time is hereby expressly declared to
be of the essence in this Agreement.

         16.12.  Confidentiality.  Except for disclosure to its bankers,
underwriters or lenders, or as necessary or desirable for conduct of business,
including negotiations with other acquisition candidates, neither party hereto
shall disseminate or release to any third party any information regarding any
provisions of this Agreement, or any financial information regarding the other
(past, present or future) that was obtained by the other in the course of the
negotiations of this Agreement or in the course of the performance of this
Agreement, without the other party's written approval; provided, however, the
foregoing shall not apply to information which (i) is generally available to
the public other than as a result of a breach of confidentiality provisions;
(ii) becomes available on a non-confidential basis from a source other than the
other party or its affiliates or agents, which source was not itself bound by a
confidentiality agreement, or (iii) which is required to be disclosed by law or
pursuant to court order.

         16.13.  Contract Modifications for Prospective Legal Events.  In the
event any state or federal laws or regulations, now existing or enacted or
promulgated after the effective date of this Agreement, are interpreted by
judicial decisions, a regulatory agency or legal counsel in such a manner as to
indicate that the structure of this Agreement may be in violation of such laws
or regulations, the Provider and Response shall amend this Agreement as
necessary.  To the maximum extent possible, any such amendment shall preserve
the underlying economic and financial arrangements between the Provider and
Response.

         16.14.  Remedies Cumulative.  No remedy set forth in this Agreement or
otherwise conferred upon or reserved to any party shall be considered exclusive
of any other remedy available to any party, but the same shall be distinct,
separate and cumulative and may be exercised from time to time as often as
occasion may arise or as may be deemed expedient.

         16.15.  Language Construction.  The language in all parts of this
Agreement shall be construed, in all cases, according to its fair meaning, and
not for or against either party hereto.  The parties acknowledge that each
party and its counsel have reviewed and revised this Agreement and that the
normal rule of construction to the effect that any ambiguities are to be
resolved against the drafting party shall not be employed in the interpretation
of this Agreement.

         16.16.  No Obligation to Third Parties.  None of the obligations and
duties of Response or the Provider under this Agreement shall in any way or in
any manner be deemed to create any obligation of Response or of the Provider
to, or any rights, in, any person or entity not a party to this Agreement.

         16.17.  Communications.  The Provider and Response agree that good
communication between the parties is essential to the successful performance of
this Agreement, and each pledges to communicate fully and clearly with the
other on mattes relating to the successful operation of the Provider's practice
at a Clinic.
<PAGE>   32

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the date first written above.


                              KNOXVILLE HEMATOLOGY-ONCOLOGY ASSOCIATES, P.L.L.C.

                              By:
                                 -----------------------------------------------

                              Title:
                                    --------------------------------------------
                              
                              RESPONSE ONCOLOGY, INC.
                              
                              By:
                                 -----------------------------------------------

                              Title:
                                    --------------------------------------------
                              
                              
                              
                              PHYSICIANS:
                              
                              
                              
                              --------------------------------------------------
                              Peter W. Carter, M.D.
                              
                              
                              
                              --------------------------------------------------
                              Albert S.C. Ebenezer, M.D.
                              
                              
                              
                              --------------------------------------------------
                              Jerry M. Foster, M.D.
                              

                              
                              --------------------------------------------------
                              Allan M. Grossman, M.D.
<PAGE>   33

                    RESPONSE ONCOLOGY, INC.SERVICE AGREEMENT
                                   SCHEDULE A

BASE SERVICE FEE

         The Base Service Fee shall be equal to the sum of (i) amounts recorded
as Clinic Expenses (the "Clinic Expense Portion") plus (ii) ***% of Practice
Revenue (the "Fixed Portion").

BASE FEE

         The Base Fee shall be equal to the sum of (A) ***% of Practice Revenue
up to $***, (B) ***% of Practice Revenue between $*** and $***, and (C) ***% of
Practice Revenue between $*** and $***.

PERFORMANCE FEE

         During the entire term of the Service Agreement, including any
extended term, unless reduced in the upon the occurrence of the event described
below, a Performance Fee in an amount equal to any Annual Surplus shall be paid
to Response.  Response shall, in turn, remit, in exchange for delegated
practice management services delivered thereby, fifty percent (50%) of such
Performance Fee to Physicians' Medical Enterprises, LLC. ("PME").  In the event
PME shall, at any time during the term hereof, discontinue rendering management
services to the Provider, then the Performance Fee payable to Response shall be
equal to 50% of Annual Surplus.

         Performance Fees shall be computed on the basis of Annual Surplus
computed for each calendar year.  For any period during the term of the Service
Agreement that does not encompass an entire calendar year, the Performance Fees
for such partial period shall be computed as follows:

         a)  For any partial period that commences with the execution and
         delivery of the Service Agreement, Clinic Expenses, Physician
         Expense and Non-physician Employee Compensation from such
         commencement date until the end of the calendar year of commencement
         shall be determined. The sum of Clinic Expenses, Physician Expense,
         Non-physician Employee Compensation and ***% of Practice Revenue will
         be subtracted from Practice Revenue, with the difference then being
         divided by the number of days in such period, and the quotient
         multiplied by 365.  The computation formula set forth above will be
         applied to the annualized Annual Surplus to compute an annualized
         Performance Fee, which shall then be divided by 365 and multiplied by
         the number of days in the partial period to yield the Performance Fee
         payable with respect to such short period.

         b)  For any partial period that commences on the first day of a
         calendar year and ends prior to the last day thereof, Annual Surplus
         for the full year will be computed based on the definition thereof,
         which result shall then be divided by 365 and multiplied by the number
         of days during the partial period to yield the Performance Fees
         payable with respect to such short period.

         The foregoing calculations shall be adjusted by 50% if the Performance
Fee is reduced by reason of the PME agreement being terminated.

LIQUIDATED DAMAGES AMOUNT

         For purposes of this Agreement, the Liquidated Damages Amount shall be
the difference obtained pursuant to the following formula:  [****]; wherein (i)
*** equals *** (ii) *** equals the number of Remaining Physician Members at the
time of occurrence of a Provider Event of Default; (ii) *** equals *** x
***/***; and (iii) *** equals ***.
<PAGE>   34



PRACTICE RETAINAGE

         For purposes of this Agreement, the Practice Retainage shall equal the
sum of ***% of Practice Revenue of $*** or less, ***% of Practice Revenue
between $*** and $***, ***% of Practice Revenue between $*** and $***, ***% of
Practice Revenue between $*** and $*** and ***% of Practice Revenue in excess
of $***.


***  MATERIAL REDACTED PURSUANT TO CLAIM FOR CONFIDENTIAL TREATMENT


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