RESPONSE ONCOLOGY INC
10-Q, 1998-05-15
SPECIALTY OUTPATIENT FACILITIES, NEC
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<PAGE>   1


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-Q


    (Mark One)

         [X]      Quarterly report pursuant to Section 13 or 15(d) of the
                  Securities Exchange Act of 1934
   
                  For the quarterly period ended March 31, 1998 or

         [ ]      Transition report pursuant to Section 13 or 15(d) of the
                  Securities Exchange Act of 1934
 
                  For the transition period from           to
                                                  --------    ------------

                  Commission file number    0-15416
                                         --------------


                             RESPONSE ONCOLOGY, INC.
- --------------------------------------------------------------------------------
             (Exact name of registrant as specified in its charter)



        Tennessee                                              62-1212264
- ---------------------------------                          -------------------
(State or Other Jurisdiction                               (I. R. S. Employer
of Incorporation or Organization)                          Identification No.)


1775 Moriah Woods Blvd., Memphis, TN                               38117
- ----------------------------------------                         ----------
(Address of principal executive offices)                         (Zip Code)


                                 (901) 761-7000
- --------------------------------------------------------------------------------
              (Registrant's telephone number, including area code)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such period that the registrant was required to
file such reports), and (2) has been subject to such filing requirements for the
past 90 days.

                                Yes  X      No
                                    ----       ----

Indicate the number of shares outstanding of each of the issuer's classes of
common stock, as of the latest practicable date.

Common Stock, $.01 Par Value, 12,021,828 shares as of April 25, 1998.





                                     - 1 -
<PAGE>   2


INDEX




PART I.    FINANCIAL INFORMATION


<TABLE>
<CAPTION>
                                                                                                              Page
                                                                                                              ----
<S>                                                                                                           <C>
Item 1.    Financial Statements

           Consolidated Balance Sheets,
           March 31, 1998 and December 31, 1997------------------------------------------------------------------3

           Consolidated Statements
           of Earnings for the Three Months Ended
           March 31, 1998 and March 31, 1997---------------------------------------------------------------------4

           Consolidated Statements of
           Cash Flows for the Three Months Ended
           March 31, 1998 and March 31, 1997 --------------------------------------------------------------------5

           Notes to Consolidated
           Financial Statements----------------------------------------------------------------------------------6

Item 2     Management's Discussion and Analysis
           of Financial Condition and Results
           of Operations-----------------------------------------------------------------------------------------9


PART II.   OTHER INFORMATION


Item 5.    Market Information and Related Stockholder Matters---------------------------------------------------12


Item 6.    Exhibits and Reports on Form 8-K --------------------------------------------------------------------12


Signatures -----------------------------------------------------------------------------------------------------13
</TABLE>





                                     - 2 -
<PAGE>   3


PART I - FINANCIAL INFORMATION

ITEM 1:  FINANCIAL STATEMENTS
         RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
         CONSOLIDATED BALANCE SHEETS
         (Dollar amounts in thousands)
<TABLE>
<CAPTION>
                                                                                      March 31, 1998   December 31, 1997
                                                                                        (Unaudited)          (Note 1)
                                                                                         ---------          ---------
<S>                                                                                   <C>              <C>
ASSETS 
CURRENT ASSETS
     Cash and cash equivalents                                                           $     476          $  2, 425
     Accounts receivable, less allowance for doubtful accounts
         of $2,238 and $3,130                                                               19,771             16,910
     Supplies and pharmaceuticals                                                            2,812              2,772
     Prepaid expenses and other current assets                                               6,374              4,219
     Due from affiliated physician groups                                                   15,361             14,823
                                                                                         ---------          ---------
         TOTAL CURRENT  ASSETS                                                              44,794             41,149

     Property and equipment, less accumulated depreciation and
         amortization of $10,062 and $9,727                                                  3,570              3,555
     Deferred charges, less accumulated amortization of $428 and $513                          350                386
     Management service agreements, less accumulated amortization of $4,706
         and $4,016                                                                        102,666            103,054
     Deferred income taxes                                                                   2,618              2,618
     Other assets                                                                            1,074                931
                                                                                         ---------          ---------
         TOTAL ASSETS                                                                    $ 155,072          $ 151,693
                                                                                         =========          =========

LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES
     Accounts payable                                                                    $  10,788          $   9,751
     Accrued expenses and other liabilities                                                  5,774              4,370
     Current portion of notes payable                                                       37,837              8,537
     Current portion of capital lease obligations                                               48                 45
                                                                                         ---------          ---------
         TOTAL CURRENT LIABILITIES                                                          54,447             22,703

     Capital lease obligations, less current portion                                            27                 44
     Notes payable, less current portion                                                     5,591             35,399
     Deferred income taxes                                                                  26,348             26,162
     Minority interest                                                                         718              1,037

STOCKHOLDERS' EQUITY
     Series A convertible preferred stock, $1.00 par value, authorized 3,000,000
         shares; issued and outstanding 27,233 shares at each period end,
         liquidating preference $11.00 per share                                                27                 27
     Common Stock, $.01 par value, authorized 30,000,000 shares; issued and
          outstanding 12,021,828 and 11,972,358 shares, respectively                           120                120
     Paid-in capital                                                                       101,703            101,402
     Accumulated deficit                                                                   (33,909)           (35,201)
                                                                                         ---------          ---------
                                                                                            67,941             66,348
                                                                                         ---------          ---------
         TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                                      $ 155,072          $ 151,693
                                                                                         =========          =========
</TABLE>


See accompanying notes to consolidated financial statements.




                                     - 3 -
<PAGE>   4


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF EARNINGS (UNAUDITED)
(Dollar amounts in thousands except for share data)

<TABLE>
<CAPTION>
                                                                  Three Months Ended
                                                          ----------------------------------
                                                          March 31, 1998      March 31, 1997
                                                          --------------      --------------
<S>                                                       <C>                 <C>        
NET REVENUE                                                $    29,595         $    24,365


COSTS AND EXPENSES
     Salaries and benefits                                       5,871               5,117
     Pharmaceuticals and supplies                               15,030              11,168
     Other operating costs                                       2,958               2,576
     General and administrative                                  1,469               1,122
     Depreciation and amortization                               1,090               1,311
     Interest                                                      704               1,104
     Provision for doubtful accounts                               219                 376
                                                           -----------         -----------
                                                                27,341              22,774
                                                           -----------         -----------

EARNINGS BEFORE INCOME TAXES AND MINORITY INTEREST               2,254               1,591
     Minority owners' share of net earnings                        170                 192
                                                           -----------         -----------

 EARNINGS BEFORE INCOME TAXES                                    2,084               1,399
     Provision for income taxes                                    792                 532
                                                           -----------         -----------

NET EARNINGS                                               $     1,292         $       867
                                                           ===========         ===========

EARNINGS PER COMMON SHARE:
           Basic                                           $      0.11         $      0.09
                                                           ===========         ===========
           Diluted                                         $      0.11         $      0.09
                                                           ===========         ===========
Weighted average number of common shares:
           Basic                                            12,008,254          10,088,418
                                                           ===========         ===========
           Diluted                                          12,217,188          10,149,178
                                                           ===========         ===========
</TABLE>

See accompanying notes to consolidated financial statements.



                                     - 4 -
<PAGE>   5


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
(Dollar amounts in thousands)

<TABLE>
<CAPTION>
                                                                                        Three Months Ended
                                                                                 ----------------------------------
                                                                                 March 31, 1998      March 31, 1997
                                                                                 --------------      --------------
<S>                                                                              <C>                 <C>        
OPERATING ACTIVITIES
Net earnings                                                                          $ 1,292          $   867
Adjustments to reconcile net earnings to net cash used in operating
activities:
   Depreciation and amortization                                                        1,090            1,311
   Provision for doubtful accounts                                                        219              376
   Minority owners' share of net earnings                                                 170              192
   Changes in operating assets and liabilities net of effect of acquisitions:
   Accounts receivable                                                                 (3,080)          (2,910)
   Supplies and pharmaceuticals, prepaid expenses and other current assets             (2,128)            (505)
   Deferred charges and other assets                                                     (139)              54
   Due from affiliated physician groups                                                  (538)          (1,959)
   Accounts payable and accrued expenses                                                2,440            1,284
                                                                                      -------          -------
NET CASH USED IN OPERATING ACTIVITIES                                                    (674)          (1,290)

INVESTING ACTIVITIES
   Purchase of equipment                                                                 (350)            (240)
   Distribution to joint venture partner                                                 (489)              --
   Acquisition of non-medical assets of affiliated physician groups                       (39)              --
                                                                                      -------          -------
NET CASH USED IN INVESTING ACTIVITIES                                                    (878)            (240)

FINANCING ACTIVITIES
   Bank overdraft                                                                          --              783
   Financing costs incurred                                                                --              (18)
   Proceeds from exercise of stock options                                                300               --
   Proceeds from notes payable                                                             --            7,151
   Principal payments on notes payable                                                   (685)          (7,784)
   Proceeds from note payable to parent                                                    --            1,005
   Principal payments on capital lease obligations                                        (12)             (22)
                                                                                      -------          -------
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES                                      (397)           1,115

DECREASE IN CASH AND CASH EQUIVALENTS                                                  (1,949)            (415)
   Cash and cash equivalents at beginning of period                                     2,425              415
                                                                                      -------          -------

CASH AND CASH EQUIVALENTS AT END OF PERIOD                                            $   476           $   --
                                                                                      =======          =======
</TABLE>



See accompanying notes to consolidated financial statements.



                                     - 5 -
<PAGE>   6


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
March 31, 1998

NOTE 1 -- BASIS OF PRESENTATION

The accompanying unaudited condensed financial statements have been prepared in
accordance with generally accepted accounting principles for interim financial
information and with the instructions to Form 10-Q and Article 10 of Regulation
S-X. Accordingly, they do not include all of the information and footnotes
required for complete financial statements by generally accepted accounting
principles. In the opinion of Management, all adjustments (consisting of normal
recurring accruals) considered necessary for a fair presentation have been
included. Certain amounts have been reclassified for comparative purposes with
no effect on net earnings. Operating results for the three month period ended
March 31, 1998 are not necessarily indicative of the results that may be
expected for the year ending December 31, 1998. For further information, refer
to the consolidated financial statements and footnotes thereto included in
Response Oncology, Inc. and Subsidiaries' (the "Company's") annual report on
Form 10-K for the year ended December 31, 1997.

Net Revenue: The following table is a summary of net revenue by source for the
respective three month periods ended March 31, 1998 and 1997. Patient services
revenue is recorded net of contractual allowances and discounts of $1,355,000
and $1,701,000 for the quarters ended March 31, 1998 and 1997, respectively.

The Company's revenue from practice management affiliations includes a fee equal
to practice operating expenses incurred by the Company (which excludes expenses
that are the obligation of the physicians, such as physician salaries and
benefits) and a management fee either fixed in amount or equal to a percentage
of each affiliated oncology group's adjusted net revenue or net operating
income. In certain affiliations, the Company may also be entitled to a
performance fee if certain financial criteria are satisfied.

<TABLE>
<CAPTION>
 (In thousands)                                   Three Months Ended
                                                        March 31,
                                              --------------------------
                                                1998               1997
                                              -------            -------
<S>                                           <C>                <C>    
Net patient services revenue                  $ 8,459             $8,754
Practice management service fees               14,060             10,875
Pharmaceutical sales to physicians              5,857              4,153
Physician investigator studies                  1,219                583
                                              =======            =======
                                              $29,595            $24,365
                                              =======            =======
</TABLE>

Net Earnings Per Common Share: In February 1997, the Financial Accounting
Standards Board issued Statement of Financial Accounting Standards No. 128,
"Earnings Per Share" (SFAS 128), which changes the computation and presentation
of earnings per share. SFAS 128 requires the presentation of basic and diluted
earnings per share, replacing primary and fully diluted earnings per share
previously required. Earnings per share for all prior years presented have been
presented in accordance with SFAS 128.




                                     - 6 -
<PAGE>   7


A reconciliation of the basic earnings per share and the diluted earnings per
share computation is presented below for the three months ended March 31, 1998
and 1997.

(Dollar amounts in thousands except per share data)

<TABLE>
<CAPTION>
                                                             Three Months Ended March 31,
                                                         ----------------------------------
                                                            1998                   1997
                                                         -----------            -----------

<S>                                                       <C>                    <C>       
Weighted average shares outstanding                       12,008,254             10,088,418
Net effect of dilutive stock options and
  warrants based on the treasury stock method                208,934                 60,760
                                                         -----------            -----------
Weighted average shares and common stock
  equivalents                                             12,217,188             10,149,178
                                                         -----------            -----------

Net earnings                                             $     1,292            $       867
                                                         ===========            ===========
Diluted per share amount                                 $      0.11            $      0.09
                                                         ===========            ===========
</TABLE>

NOTE 2 -- PARENT COMPANY

Prior to July 25, 1997 Response Oncology was a subsidiary of Seafield Capital
Corporation ("Seafield"). On July 1, 1997, Seafield's Board of Directors
declared a dividend to Seafield's shareholders of all shares of common stock of
Response owned by Seafield. For each shareholder of record on July 11, 1997,
1.2447625 shares of Response common stock were distributed on July 25, 1997 for
each share of Seafield common stock outstanding. The distribution of all shares
of Response stock held by Seafield to Seafield's shareholders was effected as a
dividend. The Seafield shareholders paid no consideration for any shares of
Response stock received in the distribution.

NOTE 3 -- NOTES PAYABLE

The Company has a $45.0 million Credit Facility to fund the Company's
acquisition and working capital needs. The Credit Facility, comprised of a $35.0
million Acquisition Facility and a $10.0 million Working Capital Facility, is
collateralized by the common stock of the Company's subsidiaries. The Credit
Facility bears interest at a variable rate equal to LIBOR plus a spread between
1.5% and 2.125%, depending upon borrowing levels. At March 31, 1998, $29.2
million aggregate principal was outstanding under the Credit Facility with a
current interest rate of approximately 8.2%. The Credit Facility contains
affirmative and negative covenants which, among other things, require that the
Company maintain certain financial ratios, including minimum fixed charges
coverage, funded debt to EBITDA, net worth and current ratio. On March 31, 1998,
the Credit Facility was modified and amended, effective April 21, 1997, to
provide for redefinitions of certain restrictive covenants.

In May 1997, the Company entered into a LIBOR based interest rate swap agreement
("Swap Agreement") with an affiliate of the Company's primary lender as required
by the terms of the Credit Facility. Amounts hedged under the Swap Agreement
accrue interest at the difference between 6.42% and the thirty-day LIBOR rate
and are settled monthly. As of March 31, 1998, approximately 51% of the
Company's outstanding principal balance under the Credit Facility was hedged
under the Swap Agreement. The Swap Agreement matures in March 1999 and is
cancelable at the lender's option after July 1998.

Additionally, long-term unsecured amortizing promissory notes bearing interest
at rates from 4% to 9% were issued as partial consideration for the practice
management affiliations. Principal and interest under the long-term notes may,
at the election of the holders, be paid in shares of common stock of the Company
based upon





                                     - 7 -
<PAGE>   8
conversion rates ranging from $13.75 to $17.50. The unpaid principal amount of
the long-term notes was $14.0 million at March 31, 1998.

NOTE 4 -- INCOME TAXES

Upon the consummation of the physician practice management affiliations, the
Company recognized deferred tax assets and liabilities for the future tax
consequences attributable to differences between the financial statement
carrying amounts of purchased assets and liabilities and their respective tax
bases. Deferred tax assets and liabilities are measured using enacted tax rates
expected to apply to taxable income in the years in which those temporary
differences are expected to be recovered or settled.

NOTE 5 -- COMMITMENTS AND CONTINGENCIES

With respect to professional and general liability risks, the Company currently
maintains an insurance policy that provides coverage during the policy period
ending August 1, 1998, on a claims-made basis, for $1,000,000 per claim in
excess of the Company retaining $25,000 per claim, and $3,000,000 in the
aggregate. Costs of defending claims are in addition to the limit of liability.
In addition, the Company maintains a $10,000,000 umbrella policy with respect to
potential general liability claims. Since inception, the Company has incurred no
professional or general liability losses and as of March 31, 1998, the Company
was not aware of any pending professional or general liability claims.

The Company has a commitment to lease medical equipment under 54 month operating
leases. Annual rentals under this commitment approximate $560,000.

NOTE 6 -- DUE FROM AFFILIATED PHYSICIANS

Due from affiliated physicians consists of management fees earned and payable
pursuant to the management service agreements ("Service Agreements"). In
addition, the Company may also fund certain working capital needs of the
affiliated physicians from time to time.

NOTE 7 -- NEW ACCOUNTING STANDARDS

As of January 1, 1998, the Company adopted Statement 130, "Reporting
Comprehensive Income." Statement 130 establishes new rules for the reporting and
display of comprehensive income and its components. The adoption of this
Statement had no impact on the Company's net income or shareholder's equity.

In June 1997, the FASB issued SFAS No. 131, "Disclosures about Segments of an
Enterprise and Related Information." SFAS No. 131 requires that the Company
report financial and descriptive information about its reportable segments.
Financial information is required to be reported on the basis that is used
internally for evaluating segment performance and deciding how to allocate
resources to segments. This statement also requires that the Company report
descriptive information about the way the operating segments were determined,
the products and services provided by the operating segments, differences
between the measurements used in reporting segment information and those used in
the Company's financial statements, and changes in the measurement of segment
amounts from period to period. SFAS No. 131 is effective for financial
statements for periods beginning after December 15, 1997. The adoption of this
statement will provide additional disclosures in the financial statements for
the year ended December 31, 1998.




                                     - 8 -
<PAGE>   9


ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
         RESULTS OF OPERATIONS

OVERVIEW

Response Oncology, Inc. (the "Company") is a comprehensive cancer management
company. The Company provides advanced cancer treatment services through
outpatient facilities known as IMPACT(R) Centers under the direction of
practicing oncologists; owns the assets of and manages the nonmedical aspects of
oncology practices; and conducts clinical research on behalf of pharmaceutical
manufacturers. Approximately 400 medical oncologists are associated with the
Company through these programs. The Company opened 4 new centers in the quarter
ended March 31, 1998 bringing the total network to 52 IMPACT(R) Centers. The
network includes 28 wholly owned centers, 15 managed programs, and 9 centers
owned and operated in joint venture with a host hospital.

In January 1996, the Company implemented a diversification strategy into
physician practice management. As of March 31, 1998 the practice management
division included affiliations with 44 physicians in 12 medical oncology
practices in Florida and Tennessee. The Company has sought deep geographic
penetration in its markets believing that significant market share is crucial to
achieving efficiencies, revenue enhancements, and marketing of complete cancer
services to diverse payors including managed care. Pursuant to Service
Agreements, the Company provides management services that extend to all
nonmedical aspects of the operations of the affiliated practices. The Company is
responsible for providing facilities, equipment, supplies, support personnel,
and management and financial advisory services. The Company's resulting revenue
from Service Agreements include a fee equal to practice operating expenses
incurred by the Company and a management fee either fixed in amount or equal to
a percentage of each affiliated practice's adjusted net revenue or operating
income. In certain affiliations, the Company may also be entitled to a
performance fee if certain financial criteria are satisfied.

RESULTS OF OPERATIONS

The Company recorded net earnings for the quarter ended March 31, 1998 of
$1,292,000 or $0.11 per diluted share compared to net earnings of $867,000 or $
0.09 per diluted share for the same period in 1997. Earnings before income taxes
for the quarter ended March 31, 1998 were $2,084,000 compared to $1,399,000 for
the same period of 1997.

Net revenue for the quarter ended March 31, 1998 was $29,595,000 compared to
$24,365,000 for the quarter ended March 31, 1997, an increase of $5,230,000 or
21%. Growth in net revenue for the quarter ended March 31, 1998 was driven by;
an increase in revenue from the practice management division, increased
pharmaceutical sales to physicians and increased revenues from the clinical
research division. For the first quarter, practice management fees increased by
29%, from $10,875,000 in 1997 to $14,060,000 in 1998. The number of physicians
in practice management relationships with the Company increased from 38 on March
31, 1997 to 44 on March 31, 1998. Pharmaceutical sales to physicians increased
$1,704,000 or 41% from the first quarter of 1997 to the first quarter of 1998.
Revenue from the clinical research division increased 109% from the three month
period ended March 31, 1997 to the three month period ended March 31, 1998 for
an increase of $636,000.

While salaries and benefits expense increased $754,000 for the quarter ended
March 31, 1998 over the same period in 1997, the expense as a percentage of net
revenue decreased from 21% for the first quarter of 1997 to 20% for the first
quarter of 1998. 





                                     - 9 -
<PAGE>   10

Pharmaceuticals and supplies expense increased by $3,862,000 or 35% for the
quarter ended March 31, 1998 over the corresponding period in 1997. The Company
attributes the increase primarily to growth in the practice management division
as well as a significant increase in pharmaceutical sales to physicians.

Interest expense was $704,000 for the first quarter of 1998 as compared to
$1,104,000 for the first quarter of 1997, a decrease of $400,000 as a result of
the conversion of the note payable to Seafield to shares of the Company's common
stock during the first quarter of 1997.

LIQUIDITY AND CAPITAL RESOURCES

At March 31, 1998, the Company's working capital was $(9.7) million with current
assets of $44.8 million and current liabilities of $54.4 million. Cash and cash
equivalents represented $.5 million of the Company's current assets. Current
liabilities includes the entire principal balance under the Company's
Acquisition facility which is due in March 1999.

Cash used in operating activities was $.7 million in the first quarter of 1998
compared to cash used in operating activities of $1.3 million for the same
period in 1997. Cash used in investing activities was $.9 million and $.2
million for the quarters ended March 31, 1998 and 1997, respectively. Cash used
in financing activities was $.4 million for the first quarter of 1998 and
provided by financing activities was $1.1 million for the same period in 1997.

The Company has a $45.0 million Credit Facility to fund the Company's
acquisition and working capital needs. The Credit Facility, comprised of a $35.0
million Acquisition Facility and a $10.0 million Working Capital Facility, is
collateralized by the common stock of the Company's subsidiaries. The Credit
Facility bears interest at a variable rate equal to LIBOR plus a spread between
1.5% and 2.125%, depending upon borrowing levels. At March 31, 1998, $29.2
million aggregate principal was outstanding under the Credit Facility with a
current interest rate of approximately 8.2%. The Credit Facility contains
affirmative and negative covenants which, among other things, require that the
Company maintain certain financial ratios, including minimum fixed charges
coverage, funded debt to EBITDA, net worth and current ratio. On March 31, 1998,
the Credit Facility was modified and amended, effective April 21, 1997, to
provide for redefinitions of certain restrictive covenants.

In May 1997, the Company entered into a LIBOR based interest rate swap agreement
("Swap Agreement") with an affiliate of the Company's primary lender as required
by the terms of the Credit Facility. Amounts hedged under the Swap Agreement
accrue interest at the difference between 6.42% and the thirty-day LIBOR rate
and are settled monthly. As of March 31, 1998, approximately 51% of the
Company's outstanding principal balance under the Credit Facility was hedged
under the Swap Agreement. The Swap Agreement matures in March 1999 and is
cancelable at the lender's option after July 1998.

Additionally, long-term unsecured amortizing promissory notes bearing interest
at rates from 4% to 9% were issued as partial consideration for the practice
management affiliations. Principal and interest under the long-term notes may,
at the election of the holders, be paid in shares of common stock of the Company
based upon conversion rates ranging from $13.75 to $17.50. The unpaid principal
amount of the long-term notes was $14.0 million at March 31, 1998.

In October 1996, the Company procured a $23.5 million credit facility from
Seafield (the "Seafield Facility") to finance acquisitions and for working
capital. At December 31, 1996, $22.5 million was outstanding under the Seafield
Facility at an interest rate of 8%. On February 26, 1997, the $23.5 million loan
and accrued interest of $.6 million was converted into 3,020,536 shares of the
Company's common stock at a rate of $8 per share.






                                     - 10 -
<PAGE>   11

The Company has a commitment to lease medical equipment in 1998 under 54 month
operating leases. Annual rentals under this commitment approximate $560,000.

IMPACT OF YEAR 2000

The year 2000 issue is the result of computer programs being written using two
digits rather than four to define the applicable year. Any computer program that
has date sensitive software may recognize a date using "00" as the year 1900
rather than as the year 2000. This could result in a system failure or
miscalculations causing disruptions of operations, including, among other
things, a temporary inability to process transactions, send invoices, or engage
in similar normal business activities.

The Company has recently assessed its internal computer systems and believes
that the current systems used will properly utilize dates beyond December 31,
1999. The Company has been informed that their outside software vendors are in
the process of studying the year 2000 issue. Upon completion of the vendors'
studies which are expected in late 1998, the Company will determine the extent
to which it is vulnerable to the third parties' failure to remediate their own
year 2000 issues and the costs associated with resolving this issue.




                                     - 11 -
<PAGE>   12


PART II - OTHER INFORMATION

ITEM 5    MARKET INFORMATION AND RELATED STOCKHOLDER MATTERS

On July 1, 1997, Seafield's Board of Directors declared a dividend to Seafield's
shareholders of all shares of common stock of Response owned by Seafield. For
each shareholder of record on July 11, 1997, 1.2447625 shares of Response common
stock were distributed on July 25, 1997 for each share of Seafield common stock
outstanding. The distribution of all shares of Response stock held by Seafield
to Seafield's shareholders was effected as a dividend. The Seafield shareholders
paid no consideration for any shares of Response stock received in the
distribution.

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

         (A) EXHIBITS

10.1     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc., a Tennessee corporation and Kenneth L. Scott.

10.2     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc. and Joseph T. Clark.

10.3     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc. and Carlton Sedberry

10.4     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc. and Mary E. Clements

10.5     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc. and William H. West, M.D.

10.6     Employment Agreement effective as of January 1, 1998 by and between
         Response Oncology, Inc. and Charles Weaver, M.D.

27       Financial Data Schedule (for SEC use only)



                                     - 12 -
<PAGE>   13



                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, Response
Oncology, Inc. has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

                                    RESPONSE ONCOLOGY, INC.


                                    By:  /s/ Mary E. Clements
                                         --------------------------------------
                                         Mary E. Clements
                                         Chief Financial Officer
                                         and Principal Accounting Officer

                                         Date:  May 15, 1998

                                    By:  /s/ Dena L. Mullen
                                         --------------------------------------
                                         Dena L. Mullen
                                         Director of Finance

                                         Date: May 15, 1998

                                    By:  /s/ Peter A. Stark
                                         --------------------------------------
                                         Peter A. Stark
                                         Controller

                                         Date:  May 15, 1998




                                      -13-

<PAGE>   1
                                                                    EXHIBIT 10.1

                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and KENNETH L. SCOTT (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the Chief Operating
Officer of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Chief Executive Officer. As of the
effective date of this Employment Agreement, the Executive shall continue to
possess and assume senior operating authority and responsibility as Chief
Operating Officer of the Company, consistent with directions from the Chief
Executive Officer of the Company.

    
    


<PAGE>   2




         2.3 Location. The duties of the Executive shall be performed in the
general geographic location where the Executive maintains his principal office
at the time of execution hereof.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $185,000 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") of up to 100% of his Base Salary, in
accordance with policies and based on performance targets established annually
by the Compensation Committee of the Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.


    
    

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                                        4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

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                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1      Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 100% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 200% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and


    
    

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<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1  A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The

    
    

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<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.



    
    

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<PAGE>   7

         6.3      Noncompetition.

                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

         7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and

    
    

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<PAGE>   8



reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.


    
    

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         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6        Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.


    
    

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<PAGE>   10



         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.
         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term,

    
    

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<PAGE>   11



its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                  (i) If to the Company, at 1775 Moriah Woods Boulevard,
         Memphis, Tennessee 38117, Attention: Chairman of the Compensation
         Committee, or at such other address as may have been furnished to the
         Executive by the Company in writing; or

                  (ii) If to the Executive, at 11845 Southwest 44th Street,
         Davie, FL 33330 or such other address as may have been furnished to the
         Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    

                                     - 11 -

<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                           RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           KENNETH L. SCOTT


    
    

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<PAGE>   1
                                                                    EXHIBIT 10.2

                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and JOSEPH T. CLARK (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the President and Chief
Executive Officer of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Board of Directors. As of the effective
date of this Employment Agreement, the Executive shall continue to possess and
assume

 
<PAGE>   2



senior operating authority and responsibility as Chief Executive Officer of the
Company, consistent with directions from the Board of Directors of the Company.

         2.3 Location. The duties of the Executive shall be performed at such
locations and places as may be directed by the Board of Directors.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $234,000 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") of up to 100% of his Base Salary, in
accordance with policies and based on performance targets established annually
by the Compensation Committee of the Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.


    
    

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<PAGE>   3



                                       4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

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<PAGE>   4



                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1      Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 200% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 299% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and


    
    

                                      - 4 -

<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1  A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The

    
    

                                      - 5 -

<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.


    
    

                                      - 6 -

<PAGE>   7


         6.3      Noncompetition.

                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

        7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and

    
    

                                      - 7 -

<PAGE>   8



reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.


    
    

                                      - 8 -

<PAGE>   9



         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6 Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.


    
    

                                      - 9 -

<PAGE>   10



         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.

         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term,

    
    

                                     - 10 -

<PAGE>   11



its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                           (i) If to the Company, at 1775 Moriah Woods
         Boulevard, Memphis, Tennessee 38117, Attention: Chairman of the
         Compensation Committee, or at such other address as may have been
         furnished to the Executive by the Company in writing; or

                           (ii) If to the Executive, at 5931 Shady Grove Road,
         Memphis, TN 38120 or such other address as may have been furnished to
         the Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    

                                     - 11 -

<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                           RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           JOSEPH T. CLARK


    
    

                                     - 12 -


<PAGE>   1
                                                                    EXHIBIT 10.3

                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and CARLTON SEDBERRY (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the Executive Vice
President - Development of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Chief Executive Officer. As of the
effective date of this Employment Agreement, the Executive shall continue to
possess and

    
    

                               
<PAGE>   2



assume senior operating authority and responsibility as Executive Vice President
- - Development of the Company, consistent with directions from the Chief
Executive Officer of the Company.

         2.3 Location. The duties of the Executive shall be performed at such
locations and places as may be directed by the Chief Executive Officer.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $115,000 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") of up to 100% of his Base Salary, in
accordance with policies and based on performance targets established annually
by the Compensation Committee of the Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.


    
    

                                      - 2 -

<PAGE>   3



                                        4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

                                      - 3 -

<PAGE>   4



                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1      Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 100% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 200% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and


    
    

                                      - 4 -

<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1  A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The

    
    

                                      - 5 -

<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.

   


                                     - 6 -
<PAGE>   7

      6.3      Noncompetition.

                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

         7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and

    
    

                                     - 7 -
<PAGE>   8



reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.


    
    

                                      - 8 -

<PAGE>   9



         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6 Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.


    
    

                                      - 9 -

<PAGE>   10



         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.

         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term,

    
    

                                     - 10 -

<PAGE>   11



its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                           (i) If to the Company, at 1775 Moriah Woods
         Boulevard, Memphis, Tennessee 38117, Attention: Chairman of the
         Compensation Committee, or at such other address as may have been
         furnished to the Executive by the Company in writing; or

                           (ii) If to the Executive, at 307 Fernway Cove,
         Memphis, TN 38117 or such other address as may have been furnished to
         the Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    

                                     - 11 -

<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                           RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           CARLTON SEDBERRY

    
    

                                     - 12 -

<PAGE>   1
                                                                    EXHIBIT 10.4


                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and MARY E. CLEMENTS (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the Chief Financial
Officer of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Chief Executive Officer. As of the
effective date of this Employment Agreement, the Executive shall continue to
possess and assume senior operating authority and responsibility as Chief
Financial Officer of the Company, consistent with directions from the Chief
Executive Officer of the Company.

    
    

                             
<PAGE>   2




         2.3 Location. The duties of the Executive shall be performed at such
locations and places as may be directed by the Chief Executive Officer.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $150,000 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") of up to 100% of his Base Salary, in
accordance with policies and based on performance targets established annually
by the Compensation Committee of the Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.


    
    

                                      - 2 -

<PAGE>   3



                                       4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

                                      - 3 -

<PAGE>   4



                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1      Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 100% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 200% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and


    
    

                                      - 4 -

<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1  A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The

    
    

                                      - 5 -

<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.




     
                                      - 6 -
<PAGE>   7

         6.3      Noncompetition.

                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

         7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and

    
    

                                      - 7 -

<PAGE>   8



reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.


    
    

                                      - 8 -

<PAGE>   9



         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6      Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.


    
    

                                      - 9 -

<PAGE>   10



         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.
         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term,

    
    

                                     - 10 -

<PAGE>   11



its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                           (i) If to the Company, at 1775 Moriah Woods
         Boulevard, Memphis, Tennessee 38117, Attention: Chairman of the
         Compensation Committee, or at such other address as may have been
         furnished to the Executive by the Company in writing; or

                           (ii) If to the Executive, at 1666 Galloway, Memphis,
         TN 38112 or such other address as may have been furnished to the
         Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    

                                     - 11 -

<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                           RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           MARY E. CLEMENTS


    
    

                                     - 12 -


<PAGE>   1
                                                                    EXHIBIT 10.5

                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and WILLIAM H. WEST, M.D. (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the Chairman of the Board
of Directors of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Board of Directors. As of the effective
date of this Employment Agreement, the Executive shall continue to possess and
assume 
    
    

                             
<PAGE>   2



senior operating authority and responsibility as Chairman of the Board of
Directors of the Company, consistent with directions from the Board of Directors
of the Company.

         2.3 Location. The duties of the Executive shall be performed at such
locations and places as may be directed by the Board of Directors.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $234,000 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") of up to 100% of his Base Salary, in
accordance with policies and based on performance targets established annually
by the Compensation Committee of the Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.

    
    

                                      - 2 -

<PAGE>   3




                                        4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

                                      - 3 -

<PAGE>   4



                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1      Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 200% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 299% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and

    
    

                                      - 4 -

<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1 A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The
    
    

                                      - 5 -

<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.





                                     - 6 -
<PAGE>   7

         6.3      Noncompetition.

                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

         7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and







                                     - 7 -
<PAGE>   8

reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.






                                     - 8 -
<PAGE>   9

         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6      Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.






                                     - 9 -
<PAGE>   10

         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.

         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term, 





                                     - 10 -
<PAGE>   11

its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                           (i) If to the Company, at 1775 Moriah Woods
         Boulevard, Memphis, Tennessee 38117, Attention: Chairman of the
         Compensation Committee, or at such other address as may have been
         furnished to the Executive by the Company in writing; or

                           (ii) If to the Executive, at 4354 Walnut Grove Road,
         Memphis, TN 38117 or such other address as may have been furnished to
         the Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    


                                     - 11 -
<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                           RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           WILLIAM H. WEST, M.D.


    
    

                                     - 12 -

<PAGE>   1
                                                                    EXHIBIT 10.6

                              EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made April 21, 1998, effective as of January 1, 1998,
by and between RESPONSE ONCOLOGY, INC., a Tennessee corporation (the "Company"),
and CHARLES WEAVER, M.D. (the "Executive").

         WHEREAS, the Company is engaged in the business of providing advanced
cancer treatment services;

         WHEREAS, the Company desires to employ the Executive to devote full
time to the business of the Company and to continue as the Chief Medical Officer
of the Company; and

         WHEREAS, the Executive desires to be employed on the terms and subject
to the conditions hereinafter stated.

         NOW, THEREFORE, in consideration of the mutual covenants contained in
this Employment Agreement, the parties hereby agree as follows:

                                        1
                          POSITION AND RESPONSIBILITIES

         During the Term of this Employment Agreement, the Executive shall
perform such duties for such compensation and subject to such terms and
conditions as are hereinafter set forth.

                                        2
                                 TERM AND DUTIES

         2.1 Term; Extension. The term of this Employment Agreement (the "Term
of this Employment Agreement") will commence as of January 1, 1998, and shall
continue through December 31, 2000. On the first and each successive anniversary
of the effective date of this Employment Agreement, the Term of this Employment
Agreement shall be extended for an additional one (1) year period, unless either
party gives notice no later than such anniversary date of such party's intent
not to extend the Term of this Employment Agreement. Termination of the
Executive's employment pursuant to this Employment Agreement shall be governed
by Sections 4 and 5.

         2.2 Duties. The Executive shall devote substantially all of his time
and attention and best efforts during normal business hours to the Company's
affairs. The Executive shall have such duties and responsibilities as are
assigned to him from time to time by the Chief Executive Officer of the Company.
As of the effective date of this Employment Agreement, the Executive shall
continue to possess and assume senior operating authority and responsibility as
Chief Medical Officer of the Company, consistent with directions from the Chief
Executive Officer of the Company.

    
    

                                
<PAGE>   2




         2.3 Location. The duties of the Executive shall be performed at such
locations and places as may be directed by the Chief Executive Officer.

                                        3
                            COMPENSATION AND BENEFITS

         3.1 Base Compensation. The Company shall pay the Executive a base
salary ("Base Salary") of $226,750 per annum, subject to applicable
withholdings. Base Salary shall be payable according to the customary payroll
practices of the Company but in no event less frequently than once each month.
The Base Salary shall be reviewed annually and shall be subject to increase
according to the policies and practices adopted by the Board of Directors from
time to time.

         3.2 Annual Incentive Awards. The Company will pay the Executive annual
incentive compensation ("Incentive Bonus") in accordance with policies and based
on performance targets established annually by the Compensation Committee of the
Board of Directors.

         3.3 Additional Benefits. The Executive will be entitled to participate
in all employee benefit plans or programs and receive all benefits and
perquisites to which any salaried employee is eligible under any existing or
future plan or program established by the Company for salaried employees,
including, without limitation, all plans developed for executive officers of the
Company. The Executive will participate to the extent permissible under the
terms and provisions of such plans or programs in accordance with program
provisions. These plans or programs may include group hospitalization, health,
dental care, life or other insurance, tax qualified pension, car allowance,
savings, thrift and profit sharing plans, termination pay programs, sick leave
plans, travel or accident insurance, disability insurance, and contingent
compensation plans, including capital accumulation programs, restricted stock
programs, stock purchase programs and stock options plans. Nothing in this
Agreement will preclude the Company from amending or terminating any of the
plans or programs applicable to salaried employees or executive officers. The
Executive will be entitled to an annual paid vacation as established by the
Board of Directors.

         3.4 Business Expenses. The Company will reimburse the Executive for all
reasonable travel and other expenses incurred by the Executive in connection
with the performance of his duties and obligations under this Employment
Agreement upon the Executive's submitting proper documentation in accordance
with Company policies for expense reimbursement.

         3.5 Withholding. The Company may directly or indirectly withhold from
any payments under this Employment Agreement all federal, state, city or other
taxes that shall be required pursuant to any law or governmental regulation.


    
    

                                      - 2 -

<PAGE>   3



                                        4
            DEATH BENEFIT; DISABILITY COMPENSATION; KEY MAN INSURANCE

         4.1 Payment in Event of Death. In the event of the death of the
Executive during the Term of this Employment Agreement, the Company's obligation
to make payments under this Employment Agreement shall cease as of the date of
death, except for earned but unpaid Base Salary and Incentive Bonus which will
be paid on a pro-rated basis for that year. The Executive's designated
beneficiary will be entitled to receive the proceeds of any life or other
insurance or other death benefit programs provided or referred to in this
Employment Agreement, other than "key man" life insurance benefits.

         4.2 Disability Compensation. Notwithstanding the disability of the
Executive, the Company will continue to pay the Executive pursuant to Section 3
hereof during the Term of this Employment Agreement, unless the Executive's
employment is earlier terminated in accordance with this Employment Agreement.
In the event the disability continues for a period of three (3) months, the
Company may thereafter terminate this Employment Agreement and the Executive's
employment. Following such termination, the Company will pay the Executive
amounts equal to his regular installments of Base Salary, as of the time of
termination, for a period of the greater of (i) the remaining Term of this
Agreement or (ii) twelve (12) months from the date of such termination. All
other compensation will cease except for earned but unpaid Incentive Bonus
awards which would be payable on a pro-rated basis for the year in which the
disability occurred, through the date of termination.

         4.3 Responsibilities in the Event of Disability. During the period the
Executive is receiving payments following his disability and as long as he is
physically and mentally able to do so, the Executive will furnish information
and assistance to the Company and from time to time will make himself available
to the Company to undertake assignments consistent with his position or prior
position with the Company and his physical and mental health. If the Company
fails to make a payment or provide a benefit required as part of this Employment
Agreement, the Executive's obligation to provide information and assistance will
end.

         4.4 Definition of Disability. For purposes of this Employment
Agreement, the term "disability" will have the same meaning as is attributed to
such term, or any substantially similar term, in the Company's long term income
disability plan as in effect from time to time.

         4.5 Key-Man Life Insurance. Upon request by the Company, the Executive
agrees to cooperate with the Company in obtaining "key man" life insurance on
the life of the Executive, with death benefits payable to the Company. Such
cooperation shall include the submission by the Executive to a medical
examination and his response to inquiries regarding his medical history.


    
    

                                      - 3 -

<PAGE>   4



                                        5
                            TERMINATION OF EMPLOYMENT

         Notwithstanding anything herein to the contrary, this Employment
Agreement and the Executive's employment with the Company may be terminated by
the Company at any time, subject to the terms and provisions of this Section 5.

         5.1 Termination Without Cause; Constructive Termination.

                  5.1.1 WITHOUT A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause (hereinafter defined) or a Constructive Termination
(as hereinafter defined) and a Change in Control (hereinafter defined) shall not
have occurred within one (1) year prior thereto, the Company will continue to
pay the Executive the following:

                           (a) in a lump sum upon such termination an amount
equal to 100% of the sum of the Executive's combined (i) Base Salary as in
effect at the time of the termination and (ii) the average Incentive Bonus for
the two (2) calendar years immediately preceding the year of termination; and

                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

                  5.1.2 UPON A CHANGE IN CONTROL. If the Executive suffers a
Termination Without Cause or Constructive Termination within one (1) year
following a Change in Control, the Company will pay to the Executive the
following:

                           (a) in a lump sum upon such termination an amount
equal to the sum of (i) 200% of the Executive's combined (A) Base Salary as in
effect at the time of the termination and (B) average Incentive Bonus for the
two (2) calendar years immediately preceding the year of termination, and (ii),
to the extent that such foregoing amount or any other payment in the nature of
compensation (within the meaning of Section 280G of the Internal Revenue Code of
1986, as amended, and the regulations promulgated thereunder ("Section 280G"))
to or for the benefit of the Executive (or any part of such amount or other
payment) constitutes an "excess parachute payment" within the meaning of Section
280G, the amount, if any, of (A) such "excess parachute payment" multiplied by a
fraction, the numerator of which is the number one (1.00) and the denominator of
which is (I) the number one (1.00) minus (II) the effective tax rate under
Section 280G applicable to the Executive expressed as a decimal, minus (B) the
amount of such "excess parachute payment" (such amount being sometimes
hereinafter called the "Excise Tax Gross-Up"); and


    
    

                                      - 4 -

<PAGE>   5



                           (b) for the greater of (i) the remaining term of this
Employment Agreement or (ii) twelve (12) months following such Termination
Without Cause or Constructive Termination, the Company shall reimburse the
Executive for the cost of the Executive's major medical health insurance as in
effect at the date of termination. The exercisability of stock options granted
to the Executive shall be governed by any applicable stock option agreements and
the terms of the respective stock option plans.

         Notwithstanding the provisions of the foregoing subparagraph (a), if
the Excise Tax Gross- Up required to be paid by the Company to all other
employees of the Company ("Affected Employees") shall exceed $5,000,000 (the
"Gross-Up Limitation"), then the amount of Excise Tax Gross-Up payable to the
Executive shall be an amount equal to $5,000,000 times a fraction, the numerator
of which shall be the amount of Excise Tax Gross-Up computed for the Executive
before consideration of the Gross-Up Limitation, and the denominator of which
shall be the aggregate Excise Tax Gross-Up computed for all Affected Employees
before consideration of the Gross-Up Limitation.

         5.2 Termination With Cause; Voluntary Termination. If the Executive
suffers a Termination with Cause or the Executive terminates his employment with
the Company (a "Voluntary Termination"), then, whether or not there has been a
Change in Control, the Company will not be obligated to pay the Executive any
amounts of compensation or benefits following the date of termination. However,
earned but unpaid Base Salary through the date of termination will be paid in a
lump sum at such time, and Incentive Bonus, if any, for the year during which
such termination occurs will be pro rated for the portion of the year prior to
the date of termination and paid at the time of termination. The exercisability
of stock options granted to the Executive shall be governed by any applicable
stock option agreements and the terms of the respective stock option plans.

         5.3 Definitions. For purposes of this Employment Agreement, the
following terms have the following meanings:

                  5.3.1 A "Change in Control" shall occur if an event or series
of events occurs after the effective date of this Employment Agreement which
would constitute either a change in ownership of the Company, within the meaning
of Section 280G, or a change in the ownership of a substantial portion of the
Company's assets, within the meaning of Section 280G, but for purposes of this
definition, the fair market value threshold for determining "substantial portion
of the Company's assets" shall be "greater than 50%."

                  5.3.2 "Constructive Termination" means termination of the
Executive's employment by the Executive (a) from a declined reassignment of a
job that is not the equivalent of his then current position as set forth herein
(in responsibility, compensation or geographic area of service), or (b) on
account of conduct by the Company or the Board that constitutes continuous and
material interference by the Company or the Board with the Executive's
performance of his duties as set forth in Section 2 hereof or the intentional or
material breach by the Company of this Agreement. The

    
    

                                      - 5 -

<PAGE>   6



Executive shall have a period of one (1) year after termination of his
employment to assert against the Company that he suffered a Constructive
Termination, and after the expiration of such one year period, the Executive
shall be deemed to have irrevocably waived the right to such assertion.

                  5.3.3 "Termination With Cause" means termination of the
Executive's employment by the Company, acting in good faith, by written notice
to the Executive specifying the event relied upon for such termination, due to
the Executive's conviction for a felony, the Executive's perpetration of a
fraud, embezzlement or other act of dishonesty or the Executive's breach of a
trust or fiduciary duty which materially adversely affects the Company or its
shareholders.

                  5.3.4 "Termination Without Cause" means termination of the
Executive's employment by the Company other than due to the Executive's death or
disability or Termination With Cause.

                                        6
                      OTHER DUTIES OF THE EXECUTIVE DURING
                 AND AFTER THE TERM OF THIS EMPLOYMENT AGREEMENT

         6.1 Additional Information. The Executive will, upon reasonable notice,
during or after the Term of this Employment Agreement, furnish information as
may be in his possession and cooperate with the Company as may reasonably be
requested in connection with any claims or legal actions in which the Company is
or may become a party. The Executive shall receive reasonable compensation for
the time expended by him pursuant to this Section 6.1.

         6.2 Confidentiality. The Executive recognizes and acknowledges that all
information pertaining to the affairs, business, clients, customers or other
relationships of the Company, as hereinafter defined, is confidential and is a
unique and valuable asset of the Company. Access to and knowledge of this
information are essential to the performance of the Executive's duties under
this Employment Agreement. The Executive will not during the Term of this
Employment Agreement or thereafter, except to the extent reasonably necessary in
the performance of his duties under this Agreement, give to any person, firm,
association, corporation or governmental agency any information concerning the
affairs, business, clients, customers or other relationships of the Company
except as required by law. The Executive will not make use of this type of
information for his own purposes or for the benefit of any person or
organization other than the Company. The Executive will also use his best
efforts to prevent the disclosure of this information by others. All records,
memoranda, etc. relating to the business of the Company whether made by the
Executive or otherwise coming into his possession are confidential and will
remain the property of the Company.





                                      - 6 -

<PAGE>   7




         6.3      Noncompetition.
    
                  6.3.1 DURING THE TERM OF EMPLOYMENT. The Executive will not
Compete with the Company (as defined in Section 6.3.4 hereafter) at any time
while he is employed by the Company or receiving payments from the Company.

                  6.3.2 VOLUNTARY TERMINATION; TERMINATION WITHOUT CAUSE;
TERMINATION WITH CAUSE; CONSTRUCTIVE TERMINATION. In the event of a Voluntary
Termination, Termination With Cause, Termination Without Cause, or Constructive
Termination, with or without a Change in Control, the Executive will not Compete
with the Company for a period of one (1) year from the date of such termination;
provided that if a Voluntary Termination follows a notice by the Company under
Section 2.1 that the Term of this Employment Agreement will not be automatically
extended, there will be no restriction on the Executive's right to Compete with
the Company after the date his employment terminates.

                  6.3.3 DEFINITION OF "COMPETE" WITH THE COMPANY. For the
purposes of this Section 6, the term "Compete with the Company" means action by
the Executive, direct or indirect, for his own account or for the account of
others, either as an officer, director, stockholder, owner, partner, member,
promoter, employee, consultant, advisor, agent, manager, creditor or in any
other capacity, resulting in the Executive having any pecuniary interest, legal
or equitable ownership, or other financial or non-financial interest in, or
employment, association or affiliation with, any corporation, business trust,
partnership, limited liability company, proprietorship or other business or
professional enterprise that provides oncology services or management services
to any oncology or hematology practice within a fifty mile radius of any
location where the Company or any subsidiary or affiliate of the Company
performs such services at the date of a termination of the Executive's
employment; provided, however, that the term "Compete with the Company" shall
not include ownership (without any more extensive relationship) of a less than a
five percent (5%) interest in any publicly-held corporation or other business
entity.

                  6.3.4 REASONABLENESS OF SCOPE AND DURATION; REMEDIES. The
Executive acknowledges that the covenants contained herein are reasonable as to
geographic and temporal scope. The Executive acknowledges that his breach or
threatened or attempted breach of any provision of Section 6 would cause
irreparable harm to the Company not compensable in monetary damages and that the
Company shall be entitled, in addition to all other applicable remedies, to a
temporary and permanent injunction and a decree for specific performance of the
terms of Section 6 without being required to prove damages or furnish any bond
or other security.

                                        7
                          INDEMNIFICATION OF EXECUTIVE

         7.1 Indemnification of Executive In Third Party Proceedings. The
Company shall indemnify Executive, if Executive was or is a party, or is
threatened to be made a party to any third party proceeding, by reason of the
fact that Executive was or is an authorized representative of the Company,
against expenses, judgments, fines and amounts paid in settlement actually and

    
    

                                      - 7 -

<PAGE>   8



reasonably incurred by Executive in connection with such third party proceeding
if he acted in good faith and in a manner he reasonably believed to be in, or
not opposed to, the best interests of the Company and, with respect to any
criminal third party proceeding, had no reasonable cause to believe such conduct
was unlawful. The termination of any third party proceeding by judgment, order,
settlement, conviction or upon a plea of nolo contendere or its equivalent,
shall not of itself create a presumption that Executive did not act in good
faith and in a manner which he reasonably believed to be in or not opposed to,
the best interests of the Company, and, with respect to any criminal third party
proceeding, had reasonable cause to believe that such conduct was unlawful.

         7.2 Indemnification of Executive in Corporate Proceedings. The Company
shall indemnify Executive if he was or is a party or is threatened to be made a
party to any corporate proceeding, by reason of the fact that he was or is an
authorized representative of the Company, against expenses actually and
reasonably incurred by him in connection with the defense or settlement of such
corporate proceeding, if he acted in good faith and in a manner reasonably
believed to be in, or not opposed to, the best interests of the Company; except
that no indemnification shall be made in respect of any claim, issue or matter
as to which the Executive shall have been adjudged to be liable to the Company
unless and only to the extent that a court of competent jurisdiction or the
court in which such corporate proceeding was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, Executive is fairly and reasonably entitled to
indemnity for such expenses which a court of competent jurisdiction shall deem
proper.

         7.3 Mandatory Indemnification of Executive. To the extent that the
Executive has been successful on the merits or otherwise in defense of any third
party or corporate proceeding or in defense of any claim, issue or matter
therein, he shall be indemnified against expenses actually and reasonably
incurred by him in connection therewith.

         7.4 Determination of Entitlement to Indemnification. Any
indemnification under Section 7.1, 7.2 or 7.3 (unless ordered by a court) shall
be made by the Company only as authorized in the specific case upon a
determination that indemnification of the Executive is proper in the
circumstances because he has either met the applicable standard of conduct set
forth in Section 7.1 or 7.2 or has been successful on the merits or otherwise as
set forth in Section 7.3 and that the amount requested has been actually and
reasonably incurred. Such determination shall be made:

         (a)      by the Board of Directors by a majority vote of a quorum
                  consisting of directors who were not parties to such third
                  party or corporate proceeding; or

         (b)      if such a quorum is not obtainable or, even if obtainable, a
                  quorum of disinterested directors so directs, by independent
                  legal counsel in a written opinion; or

         (c)      by the stockholders.


    
    

                                      - 8 -

<PAGE>   9



         7.5 Advancing Expenses. Expenses actually and reasonably incurred in
defending a third party or corporate proceeding shall be paid on behalf of
Executive by the Company in advance of the final disposition of such third party
or corporate proceeding upon receipt of an undertaking by or on behalf of the
Executive to repay such amount if it shall ultimately be determined that the
Executive is not entitled to be indemnified by the Company as authorized in this
Section 7. The financial ability of the Executive to make a repayment
contemplated by this section shall not be a prerequisite to the making of an
advance.

         7.6 Certain Terms. For purposes of this Section 7:

         (a)      "corporate proceeding" shall mean any threatened, pending or
                  completed action or suit by or in the right of the Company to
                  procure a judgment in its favor or investigative proceeding by
                  the Company;

         (b)      "criminal third party proceeding" shall include any action or
                  investigation which could or does lead to a third party
                  proceeding that could result in criminal penalties, and any
                  such proceeding;

         (c)      "expenses" shall include, but not be limited to, attorneys'
                  fees and disbursements;

         (d)      "fines" shall include, but not be limited to, any excise taxes
                  assessed on a person with respect to an Executive benefit
                  plan;

         (e)      "not opposed to the best interests of the Company" shall
                  include actions taken in good faith and in a manner the
                  Executive reasonably believed to be in the interest of the
                  participants and beneficiaries of an employee benefit plan;

         (f)      "other enterprises" shall include employee benefit plans;

         (g)      "party" to a proceeding shall include a person who gives
                  testimony or is similarly involved in such proceeding;

         (h)      "third party proceeding" shall mean any threatened, pending or
                  completed action, suit or proceeding, whether civil, criminal,
                  administrative, or investigative, other than an action by or
                  in the right of the Company.

         7.7 Insurance. The Company may purchase and maintain insurance on
behalf of Executive against any liability asserted against the Executive and
incurred by the Executive in such capacity, or arising out of his status as
such, whether or not the Company would have the power or the obligation to
indemnify Executive against such liability under the provisions of this Section
7.


    
    

                                      - 9 -

<PAGE>   10



         7.8 Scope of Section. The indemnification of Executive and advancement
of expenses, as authorized by the preceding provisions of this Section 7, shall
not be deemed exclusive of any other rights to which may be entitled under any
agreement, vote of stockholders or disinterested directors or otherwise, both as
to action in an official capacity and as to action in another capacity while
employed by the Company. The indemnification and advancement of expenses
provided by or granted pursuant to this Section 7 shall continue after the
Executive ceases to be an authorized representative of the Company and shall
inure to the benefit of his heirs, executors and administrators.

         7.9 Reliance on Provisions. Executive's actions as an authorized
representative of the Company shall be deemed so done in reliance upon rights of
indemnification provided by this Section 7.

                                        8
                     CONSOLIDATION, MERGER OR SALE OF ASSETS

         Nothing in this Employment Agreement shall preclude the Company from
consolidating or merging into or with, or transferring all or substantially all
of its assets to, another corporation or organization which assumes this
Employment Agreement and all obligations and undertakings of the Company
hereunder. Upon such a consolidation, merger or sale of assets, the term "the
Company" as used herein will mean or include the other corporation or
organization and this Employment Agreement shall continue in full force and
effect. This Section 8 is not intended to modify or limit the rights of the
Executive hereunder.

                                        9
                                  MISCELLANEOUS

         9.1 Entire Agreement. This Employment Agreement contains the entire
understanding between the Company and the Executive with respect to the subject
matter and supersedes any prior employment or severance agreements between the
Company and its affiliates, and the Executive.

         9.2 Amendment; Waiver. This Employment Agreement may not be modified or
amended except in writing signed by the parties. No term or condition of this
Employment Agreement will be deemed to have been waived except in writing by the
party charged with waiver. A waiver shall operate only as to the specific term
or condition waived and will not constitute a waiver for the future or act on
anything other than that which is specifically waived.

         9.3 Severability; Modification of Covenant. Should any part of this
Employment Agreement be declared invalid for any reason, such invalidity shall
not affect the validity of any remaining portion hereof and such remaining
portion shall continue in full force and effect as if this Employment Agreement
had been originally executed without including the invalid part. Should any
covenant of this Employment Agreement be unenforceable because of its geographic
scope or term,

    
    

                                     - 10 -

<PAGE>   11



its geographic scope or term shall be modified to such extent as may be
necessary to render such covenant enforceable.

         9.4 Effect of Captions. Titles and captions in no way define, limit,
extend or describe the scope of this Employment Agreement nor the intent of any
provision thereof.

         9.5 Counterpart Execution. This Employment Agreement may be executed in
any number of counterparts, each of which shall be deemed an original, but all
of which together shall constitute one and the same instrument.

         9.6 Governing Law; Arbitration. This Employment Agreement has been
executed and delivered in the State of Tennessee and its validity,
interpretation, performance and enforcement shall be governed by the laws of
that state. Any dispute among the parties hereto shall be settled by arbitration
in Memphis, Tennessee, in accordance with the rules then obtaining of the
American Arbitration Association and judgment upon the award rendered may be
entered in any court having jurisdiction thereof. All provisions hereof are for
the protection and are intended to be for the benefit of the parties hereto and
enforceable directly by and binding upon each party. Each party hereto agrees
that the remedy at law of the other for any actual or threatened breach of this
Employment Agreement would be inadequate and that the other party shall be
entitled to specific performance hereof or injunctive relief or both, by
temporary or permanent injunction or such other appropriate judicial remedy,
writ or orders as may be decided by a court of competent jurisdiction in
addition to any damages which the complaining party may be legally entitled to
recover together with reasonable expenses of litigation, including attorney's
fees incurred in connection therewith, as may be approved by such court.

         9.7 Notices. All notices, requests, consents and other communications
hereunder shall be in writing and shall be deemed to have been made when
delivered or mailed first-class postage prepaid by registered mail, return
receipt requested, or when delivered if by hand, overnight delivery service or
confirmed facsimile transmission, to the following:

                           (i) If to the Company, at 1775 Moriah Woods
         Boulevard, Memphis, Tennessee 38117, Attention: Chairman of the
         Compensation Committee, or at such other address as may have been
         furnished to the Executive by the Company in writing; or

                           (ii) If to the Executive, at 6291 N. Whitmar Place,
         Memphis, TN 38120 or such other address as may have been furnished to
         the Company by the Executive in writing.

         9.8 Binding Agreement. This Employment Agreement shall be binding on
the parties' successors, heirs and assigns.


    
    

                                     - 11 -

<PAGE>   12



         IN WITNESS WHEREOF, the undersigned have executed this Employment
Agreement as of the date first above written.


                                            RESPONSE ONCOLOGY, INC.


                                           By:
                                                --------------------------------
                                                Frank M. Bumstead
                                                Chairman Emeritus


                                           EXECUTIVE:



                                           -------------------------------------
                                           CHARLES WEAVER, M.D.

    
    

                                     - 12 -

<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM FORM 10-Q
FOR THE PERIOD ENDED MARCH 31, 1998 AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                          DEC-31-1998
<PERIOD-START>                             JAN-01-1998
<PERIOD-END>                               MAR-31-1998
<CASH>                                             476
<SECURITIES>                                         0
<RECEIVABLES>                                   22,009
<ALLOWANCES>                                     2,238
<INVENTORY>                                      2,812
<CURRENT-ASSETS>                                44,794
<PP&E>                                          13,632
<DEPRECIATION>                                  10,062
<TOTAL-ASSETS>                                 155,072
<CURRENT-LIABILITIES>                           54,447
<BONDS>                                         43,428
                                0
                                         27
<COMMON>                                           120
<OTHER-SE>                                      67,794
<TOTAL-LIABILITY-AND-EQUITY>                   155,072
<SALES>                                         29,595
<TOTAL-REVENUES>                                29,595
<CGS>                                           23,460
<TOTAL-COSTS>                                   23,460
<OTHER-EXPENSES>                                 2,958
<LOSS-PROVISION>                                   219
<INTEREST-EXPENSE>                                 704
<INCOME-PRETAX>                                  2,254
<INCOME-TAX>                                       792
<INCOME-CONTINUING>                              1,292
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     1,292
<EPS-PRIMARY>                                      .11
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