RESPONSE ONCOLOGY INC
10-Q, 1999-08-16
SPECIALTY OUTPATIENT FACILITIES, NEC
Previous: BRAUVIN REAL ESTATE FUND LP 5, 10QSB, 1999-08-16
Next: MANUFACTURERS LIFE INSURANCE CO OF NORTH AMERICA, 10-Q, 1999-08-16



<PAGE>   1


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-Q


(Mark One)

         [X]      Quarterly report pursuant to Section 13 or 15(d) of the
                  Securities Exchange Act of 1934


                  For the quarterly period ended June 30, 1999 or

         [ ]      Transition report pursuant to Section 13 or 15(d) of the
                  Securities Exchange Act of 1934

                  For the transition period from            to
                                                 -----------  -----------

                  Commission file number   0-15416
                                         ------------



                             RESPONSE ONCOLOGY, INC.
                             -----------------------
             (Exact name of registrant as specified in its charter)



           Tennessee                                            62-1212264
- ----------------------------------                          -------------------
(State or Other Jurisdiction                               (I. R. S. Employer
 of Incorporation or Organization)                          Identification No.)


1805 Moriah Woods Blvd., Memphis, TN                               38117
- ----------------------------------------                          --------
(Address of principal executive offices)                         (Zip Code)


                                 (901) 761-7000
                                 --------------
              (Registrant's telephone number, including area code)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such period that the registrant was required to
file such reports), and (2) has been subject to such filing requirements for the
past 90 days.

                                  Yes   [X]     No    [ ]


Indicate the number of shares outstanding of each of the issuer's classes of
common stock, as of the latest practicable date.

Common Stock, $.01 Par Value, 11,968,601 shares as of August 13, 1999.



<PAGE>   2


INDEX

<TABLE>
<CAPTION>



PART I.             FINANCIAL INFORMATION


Item 1.             Financial Statements                                                                               Page
<S>                 <C>                                                                                                <C>
                    Consolidated Balance Sheets,
                    June 30, 1999 and December 31, 1998.................................................................  3

                    Consolidated Statements
                    of Earnings for the Three Months Ended
                    June 30, 1999 and June 30, 1998.....................................................................  4

                    Consolidated Statements of Earnings for
                    The Six Months Ended June 30, 1999
                    and June 30, 1998 ..................................................................................  5

                    Consolidated Statements of
                    Cash Flows for the Six Months Ended
                    June 30, 1999 and June 30, 1998 ....................................................................  6

                    Notes to Consolidated
                    Financial Statements................................................................................  7

Item 2.             Management's Discussion and Analysis
                    of Financial Condition and Results
                    of Operations....................................................................................... 12

ITEM 3.             Quantitative and Qualitative Disclosure About Market Risk........................................... 16

PART II.            OTHER INFORMATION


Item 1.             Legal Proceedings................................................................................... 17

Item 2.             Changes in Securities and Use of Proceeds........................................................... 17

Item 3.             Defaults Upon Senior Securities..................................................................... 17

Item 4.             Submission of Matters to a Vote of Security Holders................................................. 17

Item 5.             Market Information and Related Stockholder Matters.................................................. 17

Item 6.             Exhibits and Reports on Form 8.K ................................................................... 17

Signatures          .................................................................................................... 18
</TABLE>

                                      -2-

<PAGE>   3


PART I - FINANCIAL INFORMATION

ITEM 1:  FINANCIAL STATEMENTS
         RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
         CONSOLIDATED BALANCE SHEETS
         (Dollar amounts in thousands)
<TABLE>
<CAPTION>

                                                                                 June 30, 1999    December 31, 1998
ASSETS                                                                            (Unaudited)          (Note 1)
                                                                                 -------------    -----------------
<S>                                                                               <C>             <C>
CURRENT ASSETS
     Cash and cash equivalents                                                    $     3,948     $           1,083
     Accounts receivable, less allowance for doubtful accounts
         of $2,609 and $2,772                                                          20,587                22,844
     Supplies and pharmaceuticals                                                       3,069                 3,406
     Prepaid expenses and other current assets                                          5,028                 6,276
     Due from affiliated physician groups                                              17,542                18,630
                                                                                  -----------     -----------------
         TOTAL CURRENT  ASSETS                                                         50,174                52,239

     Property and equipment, less accumulated depreciation and
         amortization of $11,610 and $11,150                                            4,538                 5,273
     Deferred charges, less accumulated amortization of $9 and $496                       452                    50
     Management service agreements, less accumulated amortization of
         $6,669 and $5,160                                                             66,509                68,087
     Other assets                                                                       1,109                 1,104
                                                                                  -----------     -----------------
         TOTAL ASSETS                                                             $   122,782     $         126,753
                                                                                  ===========     =================

LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES
     Accounts payable                                                             $    13,918     $          16,528
     Accrued expenses and other liabilities                                             6,406                 7,350
     Current portion of notes payable                                                   6,949                11,107
     Current portion of capital lease obligations                                         232                   357
     Deferred income taxes                                                                473                   473
                                                                                  -----------     -----------------
         TOTAL CURRENT LIABILITIES                                                     27,978                35,815

     Capital lease obligations, less current portion                                      563                   962
     Notes payable, less current portion                                               35,321                32,290
     Deferred income taxes                                                              7,236                 7,295
     Minority interest                                                                  1,014                   981

STOCKHOLDERS' EQUITY
     Series A convertible preferred stock, $1.00 par value (aggregate
       involuntary liquidation preference $293) authorized 3,000,000 shares;
     issued and outstanding 26,631 shares                                                  27                    27
     Common stock, $.01 par value, authorized 30,000,000 shares; issued and
     outstanding 11,931,731 and 12,049,331 shares                                         119                   120
     Paid-in capital                                                                  101,561               101,912
     Accumulated deficit                                                              (51,037)              (52,649)
                                                                                  -----------     -----------------
                                                                                       50,670                49,410
                                                                                  -----------     -----------------
         TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                               $   122,782     $         126,753
                                                                                  ===========     =================
</TABLE>

See accompanying notes to consolidated financial statements.

                                     -3-
<PAGE>   4


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF EARNINGS (UNAUDITED)
(Dollar amounts in thousands except for share data)

<TABLE>
<CAPTION>

                                                               Three Months Ended
                                                        -------------------------------
                                                          June 30,           June 30,
                                                            1999               1998
                                                        ------------       ------------

<S>                                                     <C>                <C>
NET REVENUE                                             $     34,053       $     32,627

COSTS AND EXPENSES
     Salaries and benefits                                     6,442              6,201
     Pharmaceuticals and supplies                             19,756             16,367
     Other operating costs                                     2,691              3,617
     General and administrative                                1,687              1,614
     Depreciation and amortization                             1,119              1,164
     Interest                                                    843                721
     Provision for doubtful accounts                             504                392
                                                        ------------       ------------
                                                              33,042             30,076
                                                        ------------       ------------

EARNINGS BEFORE INCOME TAXES AND MINORITY INTEREST             1,011              2,551
     Minority owners' share of net earnings                     (274)              (248)
                                                        ------------       ------------

 EARNINGS BEFORE INCOME TAXES                                    737              2,303
     Provision for income taxes                                  280                875
                                                        ------------       ------------

NET EARNINGS TO COMMON STOCKHOLDERS                     $        457       $      1,428
                                                        ============       ============

EARNINGS PER COMMON SHARE:
           Basic                                        $       0.04       $       0.12
                                                        ============       ============
           Diluted                                      $       0.04       $       0.12
                                                        ============       ============
Weighted average number of common shares:
           Basic                                          11,931,731         12,040,965
                                                        ============       ============
           Diluted                                        11,961,986         12,302,259
                                                        ============       ============
</TABLE>

See accompanying notes to consolidated financial statements.


                                      -4-
<PAGE>   5


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF EARNINGS (UNAUDITED)
(Dollar amounts in thousands except for share data)

<TABLE>
<CAPTION>

                                                                Six Months Ended
                                                        -------------------------------
                                                          June 30,           June 30,
                                                            1999               1998
                                                        ------------       ------------

<S>                                                     <C>                <C>
NET REVENUE                                             $     70,362       $     62,222

COSTS AND EXPENSES
     Salaries and benefits                                    13,008             12,072
     Pharmaceuticals and supplies                             40,243             31,397
     Other operating costs                                     6,120              6,575
     General and administrative                                3,368              3,083
     Depreciation and amortization                             2,236              2,254
     Interest                                                  1,706              1,425
     Provision for doubtful accounts                             695                611
                                                        ------------       ------------
                                                              67,376             57,417
                                                        ------------       ------------

EARNINGS BEFORE INCOME TAXES AND MINORITY INTEREST             2,986              4,805
     Minority owners' share of net earnings                     (386)              (418)
                                                        ------------       ------------

 EARNINGS BEFORE INCOME TAXES                                  2,600              4,387
     Provision for income taxes                                  988              1,667
                                                        ------------       ------------

NET EARNINGS TO COMMON STOCKHOLDERS                     $      1,612       $      2,720
                                                        ============       ============

EARNINGS PER COMMON SHARE:
           Basic                                        $       0.13       $       0.23
                                                        ============       ============
           Diluted                                      $       0.13       $       0.22
                                                        ============       ============
Weighted average number of common shares:
           Basic                                          11,990,206         12,030,036
                                                        ============       ============
           Diluted                                        12,023,887         12,305,067
                                                        ============       ============
</TABLE>

See accompanying notes to consolidated financial statements.


                                      -5-
<PAGE>   6



RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
(Dollar amounts in thousands)
<TABLE>
<CAPTION>

                                                                                        Six Months Ended
                                                                                     ----------------------
                                                                                     June 30,      June 30,
                                                                                       1999          1998
                                                                                     --------      --------
  <S>                                                                                <C>           <C>
  OPERATING ACTIVITIES
  Net earnings to common stockholders                                                $  1,612      $  2,720
  Adjustments to reconcile net earnings to net cash provided by
  operating activities:
     Depreciation and amortization                                                      2,236         2,254
     Provision for doubtful accounts                                                      695           611
     Minority owners' share of net earnings                                               386           418
     Changes in operating assets and liabilities net of effect of acquisitions:
        Accounts receivable                                                             1,562        (6,587)
        Supplies and pharmaceuticals, prepaid expenses and other current assets         1,296        (2,687)
        Deferred charges and other assets                                                  54          (270)
        Due from affiliated physician groups                                             (179)       (1,947)
        Accounts payable and accrued expenses                                          (2,226)        5,868
                                                                                     --------      --------

  NET CASH PROVIDED BY OPERATING ACTIVITIES                                             5,436           380

  INVESTING ACTIVITIES
     Purchase of equipment                                                               (500)         (886)
     Acquisition of non-medical assets of affiliated physician groups                      --          (525)
                                                                                     --------      --------
  NET CASH USED IN INVESTING ACTIVITIES                                                  (500)       (1,411)

  FINANCING ACTIVITIES
     Proceeds from exercise of stock options                                               --           302
       Distributions to joint venture partners                                           (353)         (514)
       Financing costs incurred                                                          (416)           --
       Proceeds from notes payable                                                         --         1,000
     Principal payments on notes payable                                               (1,136)       (1,016)
     Principal payments on capital lease obligations                                     (166)          (33)
                                                                                     --------      --------
  NET CASH USED IN FINANCING ACTIVITIES                                                (2,071)         (261)

  INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS                                      2,865        (1,292)
     Cash and cash equivalents at beginning of period                                   1,083         2,425
                                                                                     --------      --------

  CASH AND CASH EQUIVALENTS AT END OF PERIOD                                         $  3,948      $  1,133
                                                                                     ========      ========
</TABLE>


See accompanying notes to consolidated financial statements.


                                      -6-
<PAGE>   7


RESPONSE ONCOLOGY, INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
June 30, 1999

NOTE 1 -- BASIS OF PRESENTATION

The accompanying unaudited condensed financial statements have been prepared in
accordance with generally accepted accounting principles for interim financial
information and with the instructions to Form 10-Q and Article 10 of Regulation
S-X. Accordingly, they do not include all of the information and footnotes
required for complete financial statements by generally accepted accounting
principles. In the opinion of Management, all adjustments (consisting of normal
recurring accruals) considered necessary for a fair presentation have been
included. Certain amounts have been reclassified for comparative purposes with
no effect on net earnings. Operating results for the three and six month periods
ended June 30, 1999 are not necessarily indicative of the results that may be
expected for the year ending December 31, 1999. For further information, refer
to the consolidated financial statements and footnotes thereto included in
Response Oncology, Inc. and Subsidiaries' (the "Company's") annual report on
Form 10-K for the year ended December 31, 1998.

Net Revenue:

The Company's revenue from practice management affiliations includes a fee equal
to practice operating expenses incurred by the Company (which excludes expenses
that are the obligation of the physicians, such as physician salaries and
benefits) and a management fee either fixed in amount or equal to a percentage
of each affiliated oncology group's adjusted net revenue or net operating
income. In certain affiliations, the Company may also be entitled to a
performance fee if certain financial criteria are satisfied.

Pharmaceutical sales to physicians are recorded based upon the Company's
contracts with physician groups to manage the pharmacy component of the groups'
practice. Revenue recorded for these contracts represents the cost of
pharmaceuticals plus a percentage fee.

Revenue from physician investigator studies is recorded based upon the
Company's contracts with certain pharmaceutical companies to manage clinical
trials and is generally measured on a per patient basis for monitoring and
collection of data.

The following table is a summary of net revenue by source for the respective
three and six month periods ended June 30, 1999 and 1998. Patient services
revenue is recorded net of contractual allowances and discounts of $706,000 and
$1,212,000 for the quarters ended June 30, 1999 and 1998, respectively and
$1,910,000 and $2,567,000 for the six months ended June 30, 1999 and 1998,
respectively.

<TABLE>
<CAPTION>

                                                  Three Months Ended               Six Months Ended
                 (In Thousands)                         June 30,                       June 30,
                                                -----------------------         -----------------------
                                                 1999            1998            1999            1998
                                                -------         -------         -------         -------
     <S>                                        <C>             <C>             <C>             <C>
     Net patient services revenue               $ 7,778         $10,087         $15,927         $18,545
     Practice management service fees            16,712          14,976          34,301          29,037
     Pharmaceutical sales to physicians           9,361           6,437          19,105          12,294
     Physician investigator studies                 202           1,127           1,029           2,346
                                                -------         -------         -------         -------
                                                $34,053         $32,627         $70,362         $62,222
                                                =======         =======         =======         =======
</TABLE>




                                      -7-
<PAGE>   8



Net Earnings Per Common Share:

A reconciliation of the basic earnings per share and the diluted earnings per
share computation is presented below for the three and six month periods ended
June 30, 1999 and 1998.

(Dollar amounts in thousands except per share data)
<TABLE>
<CAPTION>


                                                            Three Months Ended                       Six Months Ended
                                                                  June 30,                                 June 30
                                                       -------------------------------         -------------------------------
                                                           1999                1998                1999                1998
                                                       -----------         -----------         -----------         -----------
<S>                                                     <C>                 <C>                 <C>                 <C>
Weighted average shares outstanding                     11,931,731          12,040,965          11,990,206          12,030,036
Net effect of dilutive stock options and
   warrants based on the treasury stock method              30,255             261,294              33,681             275,031
                                                       -----------         -----------         -----------         -----------
Weighted average shares and common stock
   equivalents                                          11,961,986          12,302,259          12,023,887          12,305,067
                                                       ===========         ===========         ===========         ===========

Net earnings                                           $       457         $     1,428         $     1,612         $     2,720
                                                       ===========         ===========         ===========         ===========

Diluted per share amount                               $      0.04         $      0.12         $      0.13         $      0.22
                                                       ===========         ===========         ===========         ===========
</TABLE>



NOTE 2 -- NOTES PAYABLE

The Company has a $42.0 million Credit Facility which matures June 2002, to fund
the Company's working capital needs. The Credit Facility, comprised of a $35.0
million Term Loan Facility and a $7.0 million Revolving Credit Facility, is
collateralized by the assets of the Company and the common stock of its
subsidiaries. The Credit Facility bears interest at a variable rate equal to
LIBOR plus a spread between 1.375% and 2.5%, depending upon borrowing levels.
The Company is also obligated to a commitment fee of .25% to .5% of the unused
portion of the Line of Credit. At June 30, 1999, $37.0 million aggregate
principal was outstanding under the Credit Facility with a current interest rate
of approximately 7.5%. The Company is subject to certain affirmative and
negative covenants which, among other things, require the Company to maintain
certain financial ratios, including minimum fixed charges coverage, funded debt
to EBITDA and minimum net worth.

In June, 1999 the Company entered into a LIBOR based interest rate swap
agreement ("Swap Agreement") effective July 1, 1999 with the Company's lender as
required by the terms of the Credit Facility. Amounts hedged under the Swap
Agreement accrue interest at the difference between 5.93% and the ninety day
LIBOR rate and are settled quarterly. The Company is committed to hedge $18.0
million under the terms of the Swap Agreement. The Swap Agreement matures on
July 1, 2000.

The installment notes payable to affiliated physicians and physician practices
were issued as partial consideration for the practice management affiliations.
Principal and interest under the long-term notes may, at the election of the
holders, be paid in shares of common stock of the Company based on conversion
prices ranging from $11.50 to $17.00. The unpaid principal amount of the
long-term notes was $5.1 million at June 30, 1999 of which $3.1 million is
included in current liabilities.

NOTE 3 -- INCOME TAXES

Upon the consummation of the physician practice management affiliations, the
Company recognized deferred tax assets and liabilities for the future tax
consequences attributable to differences between the financial


                                      -8-
<PAGE>   9

statement carrying amounts of purchased assets and liabilities and their
respective tax bases. Deferred tax assets and liabilities are measured using
enacted tax rates expected to apply to taxable income in the years in which
those temporary differences are expected to be recovered or settled.

NOTE 4 -- COMMITMENTS AND CONTINGENCIES

With respect to professional and general liability risks, the Company currently
maintains an insurance policy that provides coverage during the policy period
ending August 1, 2000, on a claims-made basis, for $1,000,000 per claim in
excess of the Company retaining $25,000 per claim, and $3,000,000 in the
aggregate. Costs of defending claims are in addition to the limit of liability.
In addition, the Company maintains a $10,000,000 umbrella policy with respect to
potential professional and general liability claims. Since inception, the
Company has incurred no professional or general liability losses and as of June
30, 1999, the Company was not aware of any pending professional or general
liability claims that would have a material adverse effect on the Company's
financial condition or results of operations.

NOTE 5 -- DUE FROM AFFILIATED PHYSICIANS

Due from affiliated physicians consists of management fees earned and payable
pursuant to the management service agreements ("Service Agreements"). In
addition, the Company may also fund certain working capital needs of the
affiliated physicians from time to time.

NOTE 6 -- SEGMENT INFORMATION

The Company's reportable segments are strategic business units that offer
different services. The Company has three reportable segments: IMPACT Services,
Physician Practice Management and Cancer Research Services. The IMPACT Services
segment provides stem cell supported high-dose chemotherapy and other advanced
cancer treatment services under the direction of practicing oncologists as well
as compounding and dispensing pharmaceuticals to certain medical oncology
practices. The Physician Practice Management segment owns the assets of and
manages oncology practices. The Cancer Research Services segment conducts
clinical cancer research on behalf of pharmaceutical manufacturers.

The accounting policies of the segments are the same as those described in the
summary of significant accounting policies in the Company's annual audited
consolidated financial statements except that the Company does not allocate
interest expense, taxes or corporate overhead to the individual segments. The
Company evaluates performance based on profit or loss from operations before
income taxes and unallocated amounts. The totals per the schedules below will
not and should not agree to the consolidated totals. The differences are due to
corporate overhead and other unallocated amounts which are reflected in the
reconciliation to consolidated earnings before income taxes.


(In thousands)


<TABLE>
<CAPTION>

                                                                     Physician
                                                      IMPACT          Practice   Cancer Research
                                                     Services        Management      Services          Total
                                                     --------        ----------  ----------------     --------
  <S>                                                <C>             <C>         <C>                  <C>
  For the three months ended June 30, 1999:
  Net revenue                                        $ 17,139        $   16,712      $    202         $ 34,053
  Total operating expenses                             14,980            14,282           263           29,525
                                                     --------        ----------      --------         --------
  Segment contribution (loss)                           2,159             2,430           (61)           4,528
  Depreciation and amortization                           135               934            --            1,069
                                                     ========        ==========      ========         ========
  Segment profit (loss)                                 2,024             1,496           (61)           3,459
                                                     ========        ==========      ========         ========

  Segment assets                                       23,281            88,182         2,521          113,984
                                                     ========        ==========      ========         ========

  Capital expenditures                                    116                36            --              152
                                                     ========        ==========      ========         ========
</TABLE>


                                      -9-
<PAGE>   10

<TABLE>
<CAPTION>

                                                                  Physician
                                                  IMPACT           Practice    Cancer Research
                                                  Services        Management       Services         Total
                                                  --------        ----------   ---------------    --------
<S>                                               <C>             <C>              <C>            <C>
For the three months ended June 30, 1998:
Net revenue                                       $ 16,524        $   14,976       $  1,127       $ 32,627
Total operating expenses                            13,091            12,655            647         26,393
                                                  --------        ----------       --------       --------
Segment contribution                                 3,433             2,321            480          6,234
Depreciation and amortization                          159               828             --            987
                                                  ========        ==========       ========       ========
Segment profit                                       3,274             1,493            480          5,247
                                                  ========        ==========       ========       ========

Segment assets                                      25,912           124,158          2,496        152,566
                                                  ========        ==========       ========       ========

Capital expenditures                                    35             1,695              6          1,736
                                                  ========        ==========       ========       ========
</TABLE>

<TABLE>
<CAPTION>

Reconciliation of profit:
                                                    1999             1998
                                                  --------        ----------
<S>                                               <C>             <C>
Segment profit                                    $  3,459        $    5,247
Unallocated amounts:
  Corporate general and administrative               1,883             2,200
  Corporate depreciation and amortization               51               177
  Corporate interest expense                           788               567
                                                  --------        ----------

Earnings before income taxes                      $    737        $    2,303
                                                  ========        ==========

</TABLE>


                                      -10-
<PAGE>   11


(In thousands)

<TABLE>
<CAPTION>

                                                                  Physician
                                                  IMPACT           Practice   Cancer Research
                                                  Services        Management      Services        Total
                                                  --------        ----------  ---------------    --------
  <S>                                             <C>             <C>             <C>            <C>
  For the six months ended June 30, 1999:
  Net revenue                                     $ 35,032        $   34,301      $  1,029       $ 70,362
  Total operating expenses                          30,248            29,190           779         60,217
                                                  --------        ----------      --------       --------
  Segment contribution                               4,784             5,111           250         10,145
  Depreciation and amortization                        281             1,855            --          2,136
                                                  ========        ==========      ========       ========
  Segment profit                                     4,503             3,256           250          8,009
                                                  ========        ==========      ========       ========

  Segment assets                                    23,281            88,182         2,521        113,984
                                                  ========        ==========      ========       ========

  Capital expenditures                                 146                53             4            203
                                                  ========        ==========      ========       ========
</TABLE>

<TABLE>
<CAPTION>
                                                                  Physician
                                                  IMPACT           Practice   Cancer Research
                                                  Services        Management      Services        Total
                                                  --------        ----------  ---------------    --------
  <S>                                             <C>             <C>             <C>            <C>
  For the six months ended June 30, 1998:
  Net revenue                                     $ 30,839        $   29,037      $  2,346       $ 62,222
  Total operating expenses                          24,374            24,381         1,194         49,949
                                                  --------        ----------      --------       --------
  Segment contribution                               6,465             4,656         1,152         12,273
  Depreciation and amortization                        392             1,624            --          2,016
                                                  ========        ==========      ========       ========
  Segment profit                                     6,073             3,032         1,152         10,257
                                                  ========        ==========      ========       ========

  Segment assets                                    25,912           124,158         2,496        152,566
                                                  ========        ==========      ========       ========

  Capital expenditures                                  69             1,728             9          1,806
                                                  ========        ==========      ========       ========
</TABLE>

  Reconciliation of profit:

<TABLE>
<CAPTION>
                                                     1999            1998
                                                  --------        ----------
  <S>                                             <C>             <C>
  Segment profit                                  $  8,009        $   10,257
  Unallocated amounts:
    Corporate general and administrative             3,657             4,361
    Corporate depreciation and amortization            101               238
    Corporate interest expense                       1,651             1,271
                                                  --------        ----------

  Earnings before income taxes                    $  2,600        $    4,387
                                                  ========        ==========
</TABLE>



                                      -11-
<PAGE>   12


ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
         RESULTS OF OPERATIONS

OVERVIEW

Response Oncology, Inc. (the "Company") is a comprehensive cancer management
company. The Company provides advanced cancer treatment services through
outpatient facilities known as IMPACT(R) Centers under the direction of
practicing oncologists; compounds and dispenses pharmaceuticals to certain
medical oncology practices for a fee; owns the assets of and manages the
nonmedical aspects of oncology practices; and conducts clinical research on
behalf of pharmaceutical manufacturers. Approximately 400 medical oncologists
are associated with the Company through these programs.

In May of 1999 the results of certain breast cancer studies were released at the
meeting of the American Society of Clinical Oncology. These studies involving
the use of high dose chemotherapy sparked controversy among oncologists, and, in
the aggregate, caused confusion among patients and physicians about the role of
high dose chemotherapy in the treatment of breast cancer. Since the release of
these data, the Company's high dose chemotherapy IMPACT Center business has
slowed, as evidenced by the number of procedures in the second quarter at 256,
as compared with 333 in the second quarter of 1998. In response to the declining
demand for high-dose chemotherapy in general, the Company has closed seven of
its centers in the second quarter and plans to close an additional four in the
third quarter of 1999. The assets used in the closed centers will go into
inventory and be used in other centers as needed. As of June 30, 1999, the
Company's total network included 46 IMPACT Centers located in 23 states and the
District of Columbia. The network consists of 28 wholly owned centers, 14
managed programs, and 4 centers owned and operated in joint venture with a host
hospital.

The Company expects that the decline in procedures will continue to adversely
affect profitability in the third quarter of 1999, and there could be further
erosion in this line of business beyond 1999. In response to the release of the
data the Company has developed new protocols for metastatic breast cancer,
adjuvant breast cancer, and lymphoma utilizing therapies to follow high dose
chemotherapy in an attempt to reduce the risk of disease recurrence. Full
deployment of these protocols will take place over the next several quarters.
However, there can be no assurance that these new protocols and therapies will
be accepted by the medical oncology community or that, after appropriate trials
these protocols and therapies will prove to be effective.

During the first quarter of 1999, the Company terminated its service agreement
with one of the Company's three underperforming adjusted net revenue model
physician practice management relationships. The second of the three
underperforming service agreements was terminated by the Company in the second
quarter of 1999. The Company had established a reserve against the three service
agreements as of December 31, 1998 in accordance with Financial Accounting
Standards Board Statement No. 121 "Accounting for the Impairment of Long-Lived
Assets and for Long-Lived Assets to be Disposed of." The Company's physician
practice management division currently includes affiliations with 39
physicians in 10 medical oncology practices in Florida and Tennessee. The
Company has sought deep geographic penetration in its markets believing that
significant market share is crucial to achieving efficiencies, revenue
enhancements, and marketing of complete cancer services to diverse payors
including managed care. Pursuant to Service Agreements, the Company provides
management services that extend to all nonmedical aspects of the operations of
the affiliated practices. The Company is responsible for providing facilities,
equipment, supplies, support personnel, and management and financial advisory
services. The Company's resulting revenue from Service Agreements includes a fee
equal to practice operating expenses incurred by the Company and a management
fee either fixed in amount or equal to a percentage of each affiliated
practice's adjusted net revenue or operating income. In certain affiliations,
the Company may also be entitled to a performance fee if certain financial
criteria are satisfied.

                                      -12-
<PAGE>   13



RESULTS OF OPERATIONS

Net revenue increased 5% to $34.1 million for the quarter ended June 30, 1999,
compared to $32.6 million for the quarter ended June 30, 1998. The $2.3 million
or 23% decrease in IMPACT Center revenue and $.9 million or 82% decrease in
revenue from physician investigator studies was offset by a $3.0 million or 47%
increase in pharmaceutical sales to physicians and a $1.7 million or 11%
increase in practice management service fees. The increase in practice
management service fees was 31%, excluding the two terminated agreements
from the quarter ended June 30, 1998.

Net revenue was $70.4 million for the six months ended June 30, 1999, compared
to $62.2 million for the same period in 1998. IMPACT Center revenue decreased by
$2.6 million or 14% and revenue from physician investigator studies decreased by
$1.3 million or 57%. Pharmaceutical sales to physicians increased $6.8 million
or 55% while practice management service fees increased $5.3 million or 18%.

Supplies and pharmaceuticals expense increased $3.4 million, or 21% and $8.8
million or 28% for the quarter and six months ended June 30, 1999 over the same
periods in 1998, respectively. The increase is primarily related to increased
volume in pharmaceutical sales to physicians and greater utilization of new
chemotherapy agents with higher costs in the practice management division thus
causing a decrease in the overall operating margin.

LIQUIDITY AND CAPITAL RESOURCES

At June 30, 1999, the Company's working capital was $22.2 million with current
assets of $50.2 million and current liabilities of $28.0 million. Cash and cash
equivalents represented $3.9 million of the Company's current assets.

Cash provided by operating activities was $5.4 million in the first six months
of 1999 compared to $.4 million for the same period in 1998. This increase is
largely attributable to improved accounts receivable collections in both the
IMPACT and Physician Practice Management divisions. Cash used in investing
activities was $.5 million and $1.4 million for the six months ended June 30,
1999 and 1998, respectively. Cash used in financing activities was $2.1 million
for the six months ended June 30, 1999 and $.3 million for the same period in
1998.

The Company has a $42.0 million Credit Facility which matures June 2002, to fund
the Company's working capital needs. The Credit Facility, comprised of a $35.0
million Term Loan Facility and a $7.0 million Revolving Credit Facility, is
collateralized by the assets of the Company and the common stock of its
subsidiaries. The Credit Facility bears interest at a variable rate equal to
LIBOR plus a spread between 1.375% and 2.5%, depending upon borrowing levels.
The Company is also obligated to a commitment fee of .25% to .5% of the unused
portion of the Line of Credit. At June 30, 1999, $37.0 million aggregate
principal was outstanding under the Credit Facility with a current interest rate
of approximately 7.5%. The Company is subject to certain affirmative and
negative covenants which, among other things, require the Company to maintain
certain financial ratios, including minimum fixed charges coverage, funded debt
to EBITDA and minimum net worth.

In June, 1999 the Company entered into a LIBOR based interest rate swap
agreement ("Swap Agreement") effective July 1, 1999 with the Company's lender as
required by the terms of the Credit Facility. Amounts hedged under the Swap
Agreement accrue interest at the difference between 5.93% and the ninety day
LIBOR rate and are settled quarterly. The Company is committed to hedge $18.0
million under the terms of the Swap Agreement. The Swap Agreement matures on
July 1, 2000.

The installment notes payable to affiliated physicians and physician practices
were issued as partial consideration for the practice management affiliations.
Principal and interest under the long-term notes may, at


                                      -13-
<PAGE>   14

the election of the holders, be paid in shares of common stock of the Company
based on conversion prices ranging from $11.50 to $17.00. The unpaid principal
amount of the long-term notes was $5.1 million at June 30, 1999 of which $3.1
million is included in current liabilities.

IMPACT OF YEAR 2000

The Year 2000 Issue exists because many computer systems and applications
currently use two-digit date fields to designate a year. As the century date
occurs, computer programs, computers and embedded microprocessors controlling
equipment with date-sensitive systems may recognize Year 2000 as 1900 or not at
all. This inability to recognize or properly treat Year 2000 may result in
computer system failures or miscalculations of critical financial and
operational information as well as failures of equipment controlling
date-sensitive microprocessors. In addition, there are two other related issues,
which could also lead to miscalculations or failures: (i) some older systems'
programming assigns special meaning to certain dates, such as 9/9/99 and (ii)
the Year 2000 is a leap year.

The Company started to formulate a plan to address the Year 2000 Issue in the
second quarter of 1998. To date the Company's primary focus has been on its own
internal information technology systems, including all types of systems in use
by the Company in its operations, finance and human resources departments, and
to deal with the most critical systems first. The Company has developed a Year
2000 Plan to address all of its Year 2000 issues. The Year 2000 plan involves
the following phases: awareness, assessment, renovation, testing and
implementation. The Company has completed an assessment of its internal
information technology systems and has established a timetable for the
renovation phase of the systems. The Company has already completed the
renovation of approximately 90% of its information technology systems, including
modifying and upgrading software and purchasing new software, and continues to
renovate the remaining portions of the systems. The Company's goal is to
complete the testing and implementation phases by November 15, 1999, although
complications arising from unanticipated acquisitions might cause some delay.

The Company has also begun to assess the potential for Year 2000 problems with
the information systems of its payors and vendors. The Company expects to
complete the assessment with respect to such parties by October 31, 1999. The
Company has been provided an estimated timetable for completion of renovation
and testing that such vendors with which the Company has a material relationship
will undertake. The Company has estimated the costs that it may incur to remedy
the Year 2000 issues relating to such parties at $85,000. The Company's
diagnostic imaging equipment used to provide imaging services have computer
systems and applications, and in some cases embedded microprocessors, that could
be affected by Year 2000 issues. The Company has assessed the impact on its
diagnostic imaging equipment by contacting the vendors of such equipment. The
vendors with respect to the majority of the equipment used by the Company have
informed the Company that such equipment is Year 2000 compliant.

The Company has made an assessment of the potential for Year 2000 problems with
the embedded microprocessors in its other equipment, facilities and corporate
and regional offices, including telecommunications systems, utilities and
security systems. The Company estimates, on a preliminary basis, that the cost
of assessment, renovation, testing and implementation of its internal systems
will range from approximately $50,000 to $75,000. The major components of these
costs are: consultants, programming new software and hardware, software upgrades
and travel expenses. The Company expects that such costs will be funded through
operating cash flows. This estimate, based on currently available information,
will be updated as the Company proceeds with renovation, testing and
implementation, and may be adjusted upon receipt of more information from the
Company's vendors and other third parties and upon the design and implementation
of the Company's contingency plan. In addition, the availability and cost of
consultants and other personnel trained in this area and unanticipated
acquisitions might materially affect the estimated costs. The effects of the
aforementioned costs have had no material impact on the Company's progress as it
relates to other information

                                      -14-
<PAGE>   15

system projects and implementation.

The Company's Year 2000 issue involves significant risks. There can be no
assurance that the Company will succeed in implementing the Year 2000 Plan it is
developing. The following describes the Company's most reasonably likely
worst-case scenario, given current uncertainties. If the Company's renovated or
replaced internal information technology systems fail the testing phase, or any
software application or embedded microprocessors central to the Company's
operations are overlooked in the assessment or implementation phases,
significant problems, including delays, may be incurred in billing the Company's
major customers (Medicare, HMO's or private insurance carriers) for services
performed. If its major customers' systems do not become Year 2000 compliant on
a timely basis, the Company will have problems and incur delays in receiving and
processing correct reimbursements. If the computer systems of third parties
(including hospitals) with which the Company's systems exchange data do not
become Year 2000 compliant both on a timely basis and in a manner compatible
with continued data exchange with the Company's systems, significant problems
may be incurred in billing and reimbursement. If the systems on the diagnostic
imaging equipment utilized by the Company are not Year 2000 compliant, the
Company may not be able to provide imaging services to patients. If the
Company's vendors or suppliers of the Company's necessary supplies and power,
telecommunications and financial services fail to provide the Company with
services, the Company will be unable to provide services to its patients. If any
of these uncertainties were to occur, the Company's business, financial
condition and results of operations would be adversely affected. The Company is
unable to assess the likelihood of such events occurring or the extent of the
effect on the Company.

The Company is establishing a contingency plan to address unavoidable Year 2000
risks with internal information technology systems and with customers, vendors
and other third parties; and expects to finalize such a plan by November 15,
1999.


                                      -15-
<PAGE>   16
ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK

The Company's primary market risk exposure is to changes in interest rates
obtainable on its Credit Facility. The Company's interest rate risk objective is
to limit the impact of interest rate fluctuations on earnings and cash flows and
to lower its overall borrowings by selecting interest periods for traunches of
the Credit Facility that are more favorable to the Company based on the current
market interest rates. The Company has the option of fixing current interest
rates for interest periods of 1, 2, 3 or 6 months.

The Company is also a party to a LIBOR based interest rate swap agreement ("Swap
Agreement"), effective date July 1, 1999, with the Company's lender as required
by the terms of the Credit Facility. Amounts hedged under the Swap Agreement
accrue interest at the difference between 5.93% and the ninety day LIBOR rate
and are settled quarterly. The Swap Agreement matures July 1, 2000. The Company
does not enter into derivative or interest rate transactions for speculative
purposes.

At June 30, 1999, $37.0 million aggregate principal was outstanding under the
Credit Facility with a current interest rate of approximately 7.5%. The company
does not have any other material market-sensitive financial instruments.






                                      -16-
<PAGE>   17



PART II - OTHER INFORMATION

ITEM 1.           LEGAL PROCEEDINGS

         Not applicable.

ITEM 2.           CHANGES IN SECURITIES AND USE OF PROCEEDS

         Not applicable.

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES

         Not applicable.

ITEM 4.           SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         Not applicable.

ITEM 5.           MARKET INFORMATION AND RELATED STOCKHOLDER MATTERS

         Not applicable.

ITEM 6.           EXHIBITS AND REPORTS ON FORM 8-K

                  (A)      EXHIBITS

         10(a)    Credit Agreement dated June 10, 1999 between Registrant,
                  AmSouth Bank, Union Planters National Bank and NationsBank,
                  N.A.

         10(b)    Swap Agreement dated June 25, 1999 between Registrant and
                  NationsBank, N.A.

         27       Financial Data Schedule (for SEC use only)


                                      -17-
<PAGE>   18



                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, Response
Oncology, Inc. has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

                                         RESPONSE ONCOLOGY, INC.


                                         By:    /s/ Mary E. Clements
                                                --------------------------------
                                                Mary E. Clements
                                                Chief Financial Officer
                                                and Principal Accounting Officer

                                                Date:  August 13, 1999

                                         By:    /s/ Dena L. Mullen
                                                --------------------------------
                                                Dena L. Mullen
                                                Director of Finance

                                                Date: August 13, 1999

                                         By:    /s/ Peter A. Stark
                                                --------------------------------
                                                Peter A. Stark
                                                Controller

                                                Date:  August 13, 1999



                                      -18-

<PAGE>   1
                                                                    EXHIBIT 10-A

                                                                [EXECUTION COPY]








                                CREDIT AGREEMENT

                                      AMONG

                 RESPONSE ONCOLOGY, INC. AND CERTAIN AFFILIATES,
                                  AS BORROWERS

                                       AND

                               AMSOUTH BANK, AGENT

                                       AND

                            THE SEVERAL LENDERS FROM
                            TIME TO TIME PARTY HERETO

                      $7,000,000 REVOLVING CREDIT FACILITY
                         $35,000,000 TERM LOAN FACILITY


                            DATED AS OF JUNE 10, 1999






<PAGE>   2




                                CREDIT AGREEMENT

     THIS CREDIT AGREEMENT ("this Agreement") is entered into as of the 10th day
of June, 1999, by and among RESPONSE ONCOLOGY, INC., a Tennessee corporation
("Response"), RESPONSE ONCOLOGY MANAGEMENT OF SOUTH FLORIDA, INC., a Tennessee
corporation ("Management"), RESPONSE ONCOLOGY OF TAMARAC, INC., a Florida
corporation ("Tamarac") and RESPONSE ONCOLOGY OF FORT LAUDERDALE, INC., a
Florida corporation ("Ft. Lauderdale"; Response, Management, Tamarac and Ft.
Lauderdale are sometimes together referred to as the "Initial Participating
Entities"; Response and the Initial Participating Entities, together with all
entities that hereafter become Participating Entities, being hereafter sometimes
together referred to as the "Borrowers"); AMSOUTH BANK, an Alabama banking
corporation ("AmSouth"), and the various lenders identified on the signature
pages hereto (collectively, with all other persons that may from time to time
hereafter become Lenders hereunder by execution of an Assignment and Acceptance,
the "Lenders"); and AMSOUTH BANK, in its capacity as Agent for Lenders
("Agent").

                                    RECITALS

     WHEREAS, the Borrowers have applied to the Lenders for (i) a term loan in
the principal amount of $35,000,000 (the "Term Loan Facility") and (ii) a
revolving credit facility in an aggregate principal amount outstanding not to
exceed $7,000,000 (the "Revolving Credit Facility") the proceeds of which are to
be used by the Borrowers for general corporate purposes, including seasonal
working capital, and letters of credit issued in the ordinary course of
business.

     WHEREAS, the Lenders are willing to make the Term Loan Facility and the
Revolving Credit Facility available to the Borrowers only if, among other
things, the Borrowers enter into this Agreement and the other Credit Documents
(as hereinafter defined).

     NOW, THEREFORE, in consideration of the foregoing Recitals, and to induce
the Lenders to make the Term Loan Facility and Revolving Credit Facility
available, the Borrowers, the Lenders and the Agent agree as follows:

                                 I. DEFINITIONS

     1.1 Terms Defined in This Agreement. As used below in this Agreement, the
following capitalized terms shall have the following meanings, unless the
context expressly requires otherwise:

     "ACQUISITION EBITDA" means, with respect to a Practice acquired by a
Consolidated Entity and covered by a Service Agreement, the pro forma income to
the Consolidated Entities that would have arisen under the applicable Service
Agreement preceding the effective date of the Permitted Acquisition, determined
based upon the actual financial performance of the acquired Practice over the
period for which a calculation of Consolidated EBITDA is made, without
adjustment, in each case calculated as if the Practice had been acquired
effective as of the beginning of the relevant financial period.

     "AFFILIATE" means, with respect to any Person, another Person that,
directly or indirectly through one or more intermediaries, Controls, or is
Controlled by, or is under common Control with, such Person.
<PAGE>   3

     "AGENT" means AmSouth Bank, in its capacity as described in Article IX of
this Agreement, its lawful corporate successors and any successor agent
appointed pursuant to Article IX hereof.

     "AGREEMENT" means this Credit Agreement (including all schedules and
exhibits hereto), as originally in effect on the Closing Date and as thereafter
from time to time amended, supplemented, restated or otherwise modified and in
effect on such date.

     "AMSOUTH" means AmSouth Bank, an Alabama banking corporation, as a Lender
and its successors and assigns.

     "APPLICABLE COMMITMENT FEE," "APPLICABLE LIBO RATE MARGIN," and "APPLICABLE
PRIME RATE MARGIN" mean, with respect to any Loan and the commitment fee
respecting the Revolving Credit Loan, during any Effective Period, the
percentage rates per annum set forth opposite the appropriate test in the
pricing grid below (ratio values shall be rounded to the nearest one-hundredth,
with any value of .005 rounded upward):

<TABLE>
<CAPTION>

               Total Funded Debt to            Prime Rate      LIBOR       Commitment Fee
                Consolidated EBITDA              Margin       Margin       in Basis Points

<S>                                            <C>            <C>          <C>
Tier 1 - Less than or equal to 2.00                0%          1.375%             25bps

Tier 2 - Greater than or equal to 2.01           .25%           1.75%           37.5bps
and less than or equal to 2.50

Tier 3 - Greater than or equal to 2.51          .625%          2.125%           37.5bps
and less than or equal to 3.00

Tier 4 - Greater than 3.01                      1.00%           2.50%             50bps
</TABLE>


The Total Funded Debt to Consolidated EBITDA ratio shall be established by Agent
on the basis of the consolidated quarterly financial statements of and schedules
prepared by Response delivered to Agent pursuant to this Agreement and shall be
calculated as set forth in Section 7.3 hereof. Notwithstanding the foregoing, at
the end of any Effective Period, and during any period of time for which Pricing
Values may be set by Agent pursuant to Section 8.1.5 hereof, the Pricing Values
with respect to the Loans shall automatically become the highest values provided
for in the applicable pricing grid set forth above. From the Closing Date until
September 1, 1999, the Pricing Values shall be Tier 4.

     "ASSIGNMENT AND ACCEPTANCE" means an Assignment and Acceptance in the form
of Exhibit 10.12 (with blanks appropriately completed) delivered in connection
with an assignment of a portion of a Lender's interest under this Agreement
pursuant to Section 10.12.

     "ASSUMPTION AGREEMENT" has the meaning attributed to that term in Section
1.3.6.

     "ASSUMED DEBT" means Purchase Money Debt assumed by a Consolidated Entity.

     "BANKING DAY" means a Business Day, subject to the following additional
convention. As to notices or payments received by Agent on a Business Day at or
before 12:00 p.m. (noon) Nashville, Tennessee time, the Banking Day shall
correspond to the Business Day of receipt. As to notices or payments received by
Agent on a Business Day after 12:00 p.m. (noon) Nashville, Tennessee time, the
Banking Day of receipt shall be deemed to be the next following Business Day.

                                      2
<PAGE>   4

     "BANKRUPTCY CODE" means Title I of the Bankruptcy Reform Act of 1978, as it
may be amended from time to time.

     "BEST OF BORROWER'S KNOWLEDGE" means the actual knowledge, information and
belief of the Chairman, Chief Executive Officer, Chief Financial Officer, and
General Counsel of Borrowers, with no duty of inquiry.

     "BORROWERS" has the meaning attributed to that term in the preamble to this
Agreement.

     "BORROWING NOTICE" has the meaning assigned in Section 2.5.1(b) hereof.

     "BUSINESS DAY" means any day on which Agent is open for the conduct of
ordinary business; provided however, that when used in connection with
determining the LIBO Rate, the term "Business Day" shall exclude any day on
which banks are not open for dealings in U.S. Dollar deposits in the London
Interbank Market.

     "CAPITAL EXPENDITURES" means expenditures, determined according to GAAP on
a consolidated basis, that would be capitalized and depreciated over more than
one annual accounting period.

     "CAPITAL LEASE" means a lease that would be characterized as a financed
sale or purchase under GAAP.

     "CHANGE OF CONTROL" means the occurrence, after the Closing Date, of (i)
any Person or two or more Persons acting in concert acquiring beneficial
ownership (within the meaning of Rule 13d-3 of the Securities and Exchange
Commission under the Securities Exchange Act of 1934, as amended), directly or
indirectly, of securities of Response (or other securities convertible into such
securities) representing 51% or more of the combined voting power of all
securities thereof entitled to vote in the election of directors; or (ii) during
any period of up to 12 consecutive months, commencing after the Closing Date,
individuals who at the beginning of such 12-month period were directors of
Response ceasing for any reason to constitute a majority of the Board of
Directors thereof unless the Persons replacing such individuals were nominated
by the Board of Directors of Response; or (iii) any Person or two or more
Persons acting in concert acquiring by contract or otherwise, or entering into a
contract or arrangement which upon consummation will result in its acquisition
of, or control over, securities of Response (or other securities convertible
into such securities) representing 51% or more of the combined voting power of
all securities of Response entitled to vote in the election of directors.

     "CLOSING DATE" means June 10, 1999.

     "CMLTD" means scheduled principal paid on Long-Term Liabilities during the
period in question.

     "COLLATERAL" means all Property now or hereafter securing the Obligations.

     "COMMITMENT" means, for any Lender, such Lender's Term Loan Commitment plus
its Revolving Credit Commitment.

     "CONSOLIDATED CAPITAL" means Consolidated Net Worth plus Total Funded Debt.

                                       3
<PAGE>   5

     "CONSOLIDATED EBITDA" means the EBITDA of the Borrowers, determined on a
consolidated basis, and adjusted as follows with respect to acquisitions. The
positive Acquisition EBITDA of acquired Practices shall be included in
Consolidated EBITDA only if Agent is satisfied, in its reasonable discretion, as
to the accuracy and reliability of the financial information related thereto. In
assessing the accuracy and reliability of such financial information, (i)
unqualified audited financial statements prepared by a regional or national
accounting firm shall be acceptable, and (ii) financial statements reviewed (but
not audited) by such a firm shall also be acceptable unless Agent in good faith
determines that reviewed statements for a particular enterprise are subject to
material doubt as to their accuracy. The negative Acquisition EBITDA for any
Practice shall be included in Consolidated EBITDA, based upon the best
information available. Notwithstanding any other provision hereof, an amount not
to exceed $29,126,000 shall not be included in the calculation of Consolidated
EBITDA through the fiscal quarter ending September 30, 1999.

     "CONSOLIDATED ENTITIES" means a Person whose financial statements are
appropriately consolidated with Response's financial statements under GAAP.

     "CONSOLIDATED NET INCOME" means net income, determined on a consolidated
basis according to GAAP.

     "CONSOLIDATED NET REVENUES" means, for any fiscal quarter, the net revenues
of Response and its Subsidiaries, on a consolidated basis and excluding
intercompany items, for such quarter, determined in accordance with GAAP.

     "CONSOLIDATED NET WORTH" means shareholders' equity, determined on a
consolidated basis according to GAAP.

     "CONTROL" or "CONTROLLED" means that a Person has the direct or indirect
power to conduct or govern the policies of another Person, whether this power
exists as a matter of right or through economic compulsion.

     "CREDIT DOCUMENTS" means, collectively, each writing delivered at any time
by Borrowers to Lenders or Agent relating to the Loans, the Swingline Loans, any
Hedge Agreement or to any Letters of Credit, or to evidence or secure any of the
Obligations.

     "CREDIT FACILITY" means the Term Loan Facility or the Revolving Credit
Facility, as the context may require.

     "DEFAULT RATE" means a rate of interest equal to two percentage points (200
basis points) in excess of the highest interest rate that would otherwise be
payable on the principal amount of the Obligations under the Credit Documents
from time to time in the absence of the existence of a default, or the maximum
rate permitted by law, whichever is less.

     "EBITDA" means the sum of net income before extraordinary items plus
Interest Expense and expenses for taxes, depreciation and amortization,
determined according to GAAP, less Provider Loans with no adjustments for
extraordinary gains or losses.

     "EFFECTIVE PERIOD" means a period of up to one calendar quarter, determined
as follows: Pursuant to other provisions of this Agreement, Response's financial
information for each quarter-end is to be submitted during the succeeding
quarter. The performance pricing provisions of this Agreement reevaluate pricing
quarterly, based upon those quarterly financial results. An Effective

                                       4
<PAGE>   6

Period imposing pricing based upon a quarter shall begin on the first day of the
third month of the following fiscal quarter. The Effective Period shall end on
the last day of the second month of each fiscal quarter following the quarter in
which the Effective Period was scheduled to begin. Therefore, assuming the
timely delivery of all required financial statements, the Effective Periods will
be determined as follows:

<TABLE>
<CAPTION>

         Financial Statements Due By        Effective Period
         ---------------------------        ----------------
         <S>                                <C>
                 May 15                      June 1 - August 31
                 August 15                   September 1 - November 30
                 November 15                 December 1 - February 28/29
                 March 1                     March 1 - May 31
</TABLE>

     "ENCUMBRANCE" means any interest in Property in favor of one not the owner
thereof, whether voluntary or involuntary, including, but not limited to, (i)
the lien or security interest arising from a deed of trust, mortgage, pledge,
security agreement, conditional sale, Capital Lease, consignment, or bailment
for security purposes, and (ii) reservations, exceptions, encroachments,
easements, rights-of-way, covenants, conditions, restrictions, leases, and other
such title encumbrances.

     "ENVIRONMENTAL LAWS" means the Environmental Protection Act, the Resource
Conservation and Recovery Act of 1976, the Comprehensive Environmental Response,
Compensation and Liability Act of 1980, the Hazardous Materials Transportation
Act and any other federal, state or municipal law, rule or regulation relating
to air emissions, water discharge, noise emissions, solid or liquid waste
disposal, hazardous or toxic waste or materials, or other environmental or
health matters.

     "ERISA" means the Employee Retirement Income Security Act of 1974, as
amended from tune to time, including (unless the context otherwise requires) any
rules or regulations promulgated thereunder.

     "ERISA AFFILIATE" means any Person who for purposes of Title IV of ERISA is
a member of Response's controlled group, or under common control with Response,
within the meaning of Section 414 of the IRC, the regulations promulgated
pursuant thereto and the published revenue rulings issued thereunder.

     "ERISA EVENT" means (i) the occurrence of a reportable event, within the
meaning of Section 4043 of ERISA, unless the 30-day notice requirement with
respect thereto has been waived by the PBGC; (ii) the provision by the
administrator of any Plan of a notice of intent to terminate such Plan, pursuant
to Section 404 1(a)(2) of ERISA (including any such notice with respect to a
plan amendment referred to in Section 4041(e) of ERISA); (iii) the cessation of
operations at a facility in the circumstances described in Section 4068(f) of
ERISA; (iv) the withdrawal by Response or an ERISA Affiliate from a Multiple
Employer Plan during a plan year for which it was a substantial employer, as
defined in 4001(a)(2) of ERISA; (v) the failure by Response or any ERISA
Affiliate to make a material payment to a Plan required under Section 302(f)(1)
of ERISA; (vi) the adoption of an amendment to a Plan requiring the provision of
initial or additional security to such Plan, pursuant to Section 307 of ERISA;
or (vii) the institution by the PBGC of proceedings to terminate a Plan,
pursuant to Section 4042 of ERISA, or the occurrence of any event or condition
which might constitute grounds under Section 4042 of ERISA for the termination
of, or the appointment of a trustee to administer, a Plan.

                                       5
<PAGE>   7

     "EVENT OF DEFAULT" means the occurrence of any of the events specified in
Section 8.1 hereof, as to which any requirement for notice or lapse of time has
been satisfied.

     "FINANCIAL STATEMENTS" means the audited consolidated balance sheet, income
statement, and statement of cash flows for Response dated December 31, 1998
delivered by Response to Lenders, and all notes thereto.

     "FIXED CHARGE COVERAGE RATIO" means for any fiscal quarter (i) Consolidated
EBITDA for such quarter, plus expenses incurred under Operating Leases for such
quarter, and less Maintenance Capital Expenditures for such quarter, less
Provider Loans for such quarter, and less cash taxes for such quarter divided by
(ii) the sum of Interest Expense paid during such quarter plus CMLTD (excluding
Subordinated Debt), plus current maturities of the principal component of
Capital Leases paid during such quarter, plus expenses incurred under Operating
Leases for such quarter. The values for the fixed charges used in the
calculation of this ratio will be determined on a pro forma basis as though the
acquisitions occurring during the period over which the Fixed Charge Coverage
Ratio is being determined had occurred as of the beginning of that period, with
such calculations to take into account, along with other adjustments that Agent
may approve, in its reasonable discretion, (i) the exclusion of Interest
Expense, CMLTD, Capital Lease expense and Operating Lease expense of the target
related to debts, leases and obligations that were extinguished in connection
with the acquisition, (ii) the inclusion of Interest Expense, CMLTD, Capital
Lease expense and Operating Lease expense obligations of the target that
survived the acquisition, and (iii) the inclusion of Interest Expense, CMLTD,
Capital Lease expense and Operating Lease Expense arising from obligations
incurred in connection with the acquisition (including, but not limited to,
added Interest Expense arising from Seller Debt or from Loans advanced under
this Agreement incidental to the acquisition).

     "FRAUD AND ABUSE LAWS" means Section 1128B(b) of the Social Security Act,
42 U.S.C. Section 1320a-7b(b) and Section 1877 of the Social Security Act, 42
U.S.C. Section 1877, as from time to time amended; any successor statute(s)
thereto; all rules and regulations promulgated thereunder; and any other Law
relating to the ownership of medical facilities by providers of medical services
or the referral of patients to medical facilities owned by providers of medical
services.

     "GAAP" means generally accepted accounting principles pronounced by the
Financial Accounting Standards Board or any successor thereto, as in effect from
time to time.

     "GOVERNMENTAL AUTHORITY" means any governmental or quasi-governmental
entity, court or tribunal including, without limitation, any department,
commission, board, bureau, agency, administration, service or other
instrumentality of any foreign or domestic governmental entity.

     "HAZARDOUS SUBSTANCES" means those substances included from time to time
within the definition of hazardous substances, hazardous materials, toxic
substances, or solid waste under the Comprehensive Environmental Response,
Compensation and Liability Act of 1980 as amended, 42 U.S.C. ss. 9601 seq.; the
Resource Conservation and Recovery Act of 1976, 42 U.S.C. ss. 6901 et seq.; the
Hazardous Materials Transportation Act, 49 U.S.C. ss. 1801 et seq.; the Clean
Water Act, 33 U.S.C. Section 1251 et. seq.; the Toxic Substances Control Act, 15
U.S.C. Section 2601 et seq.; and in the regulations promulgated pursuant to such
acts and laws; and such other substances that are or become regulated under any
applicable local, state, or federal law or regulation addressing environmental
hazards.

                                       6
<PAGE>   8

     "HEDGE AGREEMENT" means any agreement between Response and any Lender now
existing or hereafter entered into, which provides for an interest rate or
commodity swap, cap, floor, collar, forward foreign exchange transaction,
currency swap, cross-currency rate swap, currency option, or any combination of,
or option with respect to, these or similar transactions, for the purpose of
hedging Response's exposure to fluctuations in interest rates, currency
valuations or commodity prices.

     "IMPACT CENTER" means a high dose chemotherapy cancer treatment center
operated by a Consolidated Entity.

     "INTEREST EXPENSE" means (i) expenses for interest (and including the
interest portion of current charges on Capital Leases), (ii) expenses for
Letters of Credit and (iii) expenses for any interest rate swaps or similar
derivative contracts used for the management of interest expense.

     "INTEREST PAYMENT DATE" means, (i) as to Prime Rate Loans and Swingline
Loans, the first day of each month, and (ii) as to any LIBOR Loan, the last day
of the Interest Period applicable to such Loan and, in addition, in the case of
a LIBOR Loan with an Interest Period of six (6) months' duration, the
numerically corresponding day (or, if there is no numerically corresponding day,
on the last day) in the calendar month that is 3 months, after the commencement
of the Interest Period.

     "INTEREST PERIOD" means, as to any LIBOR Loan, the period commencing on
(and including) the date of such LIBOR Loan and ending on (but excluding) the
numerically corresponding day (or, if there is no numerically corresponding day,
on the last day) in the calendar month that is 1, 2, 3 or 6 months thereafter,
as Borrower may elect; provided, however, that (x) if any Interest Period would
end on a day that is not a Business Day, such Interest Period shall be extended
to the next succeeding Business Day unless, with respect to LIBOR Loans, such
next succeeding Business Day would fall in the next calendar month, in which
case such Interest Period shall end on the next preceding Business Day and (y)
no Interest Period with respect to any Loan shall end later than the Maturity
Date. Interest shall accrue from and including the first Banking Day of an
Interest Period to but excluding the last Banking Day of such Interest Period.

     "IRC" means the Internal Revenue Code of 1986, as amended from time to
time.

     "ISSUING BANK" means, with respect to each Letter of Credit, the Lender
that issues such Letter of Credit as provided in Section 2.16.

     "LAW" or "LAWS" means all applicable constitutional provisions, statutes,
codes, acts, ordinances, orders, judgments, decrees, injunctions, rules,
regulations, and requirements of all Governmental Authorities.

     "LENDER" means (a) AmSouth in its capacity as a Lender and each Person
listed on the signature pages hereto and identified as a Lender and (b) each
Person that becomes an Assignee pursuant to the provisions of Section 10.12.

     "LETTERS OF CREDIT" has the meaning assigned in Section 2.16 of this
Agreement.

     "LETTER OF CREDIT DOCUMENTS" has the meaning assigned in Section 2.16.3 of
this Agreement.

     "LETTER OF CREDIT LIABILITIES" has the meaning assigned in Section 2.16 of
this Agreement.

                                       7
<PAGE>   9

     "LIABILITY" or "LIABILITIES" means, with respect to any Person, an
obligation, contingent or otherwise, that would be recorded or accrued under
GAAP as a liability of that Person including, but not limited to, any
nonrecourse obligation secured by Property of that Person.

     "LIBO RATE" means, for any given Interest Period with respect to a given
LIBOR Loan, the rate per annum appearing on Telerate Page 3750 (or any successor
page) as the London interbank offered rate for deposits in Dollars at
approximately 11:00 a.m. (London time) two Business Days prior to the first day
of such Interest Period for a term comparable to such Interest Period. If for
any reason such rate is not available, the term LIBO Rate shall mean, for any
given Interest Period with respect to a given LIBOR Loan, the rate per annum
appearing on Reuters Screen LIBO Page as the London interbank offered rate for
deposits in Dollars at approximately 11:00 a.m. (London time) two Business Days
prior to the first day of such Interest Period for a term comparable to such
Interest Period; provided, however, if more than one rate is specified on
Reuters Screen LIBO Page, the applicable rate shall be the arithmetic mean of
all such rates.

     "LIBO RATE RESERVE PERCENTAGE" means the reserve percentage applicable
during any Interest Period (or if more than one such percentage shall be so
applicable, the daily average of such percentages for those days in such
Interest Period during which any such percentage shall be so applicable) under
regulations issued from time to time by the Board of Governors of the Federal
Reserve System (or any successor) for determining the maximum reserve
requirement (including, without limitation, any emergency, supplemental or other
marginal reserve requirement) for Lenders with respect to liabilities or assets
consisting of or including LIBOR Liabilities having a term equal to such
Interest Period.

     "LIBOR LIABILITIES" means deposit liabilities incurred through the London
Interbank Market.

     "LIBOR LOAN" means a Loan for which Response has elected application of an
interest rate based on the LIBO Rate.

     "LOAN" means and collectively refer to the Term Loans, loans advanced under
the Revolving Credit Loan or, when the context so requires, advanced as a
Swingline Loan.

     "LONG-TERM LIABILITIES" means Liabilities all or a portion of which are not
payable in accordance with their terms within one year from the date on which
such determination is being made.

     "MAINTENANCE CAPITAL EXPENDITURES" means Capital Expenditures other than
those related to Permitted Acquisitions and shall include, without limitation, a
charge of $150,000 per physician clinic per year, a charge of Ten Thousand and
No/100 Dollars ($10,000.00) per year per wholly-owned IMPACT Center and Five
Thousand and No/100 Dollars ($5,000.00) per year for each IMPACT Center that is
not wholly-owned by a Consolidated Entity.

     "MATERIAL ADVERSE CHANGE" means any material and adverse change in the
business, Properties, or operations of the Consolidated Entities.

     "MATERIAL ADVERSE EFFECT" means any event or condition which, singly or in
the aggregate with other events or conditions, materially and adversely affects
the business, Properties, or operations of the Consolidated Entities, considered
collectively.

     "MATURITY DATE" means June 10, 2002.

                                       8
<PAGE>   10

     "MAXIMUM LAWFUL AMOUNT" means the maximum lawful amount of interest, loan
charges, commitment fees or other charges that may be assessed under Tennessee
law or, if higher, under applicable federal law.

     "NET PROCEEDS" means gross proceeds of a transaction less reasonable and
customary underwriter and brokerage fees and commissions, the fees and expenses
of trustees and attorneys, and other reasonable and customary closing fees and
expenses.

     "NOTES" means any of the Revolving Credit Notes, the Term Notes and the
Swingline Note.

     "OBLIGATIONS" means the obligations of Borrower to Lenders to repay the
Loans, the obligation of Borrowers to the Swingline Lender to repay the
Swingline Loans, and all other obligations of Borrowers and the Consolidated
Entities to Lenders and to Agent under this Agreement and the other Credit
Documents.

     "OPERATING LEASES" means leases that are not Capital Leases.

     "PARTICIPATING ENTITY" means any Subsidiary that (i) hereafter executes and
delivers to the Agent an Assumption Agreement and all other documents necessary
to assume joint and several liability as to the Obligations, (ii) is owned, in
both economic interest and voting rights, by Response in an amount exceeding
50%, (iii) is owned by Response in a proportion sufficient to allow Response to
Control the Subsidiary, including the right to cause the Subsidiary to make
lawful distributions of income, and the financial interest of Response therein
is, in Agent's reasonable judgment, freely alienable by Response through a
security interest granted therein or otherwise, and (iv) as to which Response
has granted to Agent as additional security for the Loans, a first priority
perfected security interest in its stock or other equity interest in the
Subsidiary pursuant to documentation in form and substance acceptable to Agent
and its counsel, with the validity and perfection of the security interest and
other matters as Agent may reasonably require confirmed to Agent by an opinion
of Response's outside counsel satisfactory to Agent in all respects, and with
all expenses related to such documentation (including, but not limited to,
filing fees and taxes and the reasonable fees and expenses of Lenders' and
Agent's attorneys) to be paid by Response.

     "PBGC" means the Pension Benefit Guaranty Corporation and any entity
succeeding to any or all of its functions under ERISA.

     "PERMITTED ACQUISITION" means the acquisition (by asset purchase, stock
purchase, merger or otherwise, subject to the other requirements of this
definition set forth below) by Response or another Consolidated Entity of the
assets of a Practice in the ordinary course of business (it being acknowledged
that medical records and certain other professional assets that are required by
Law to be owned by a physician Provider are not acquired in these transactions),
which purchase meets all of the following criteria:

(a)  The form of the acquisition shall have been of the assets of a Practice (by
     merger or otherwise) or, if for stock or other equity interest, the target
     acquired shall become a Participating Entity concurrently with the closing
     of the acquisition.

(b)  Response shall have delivered to Agent, prior to closing the acquisition,
     unaudited pro forma financial statements demonstrating continued compliance
     with all covenants in this Agreement following the acquisition.

                                       9
<PAGE>   11

(c)  Agent shall have issued its written consent to the acquisition prior to the
     closing thereof and following receipt and review of an Acquisition
     Certificate in the form attached hereto as Exhibit 1.2; provided, however,
     an acquisition by Response of a Practice employing two physicians or less
     where proceeds of such Acquisition are $2,000,000 or less, will not require
     approval of the Agent or the Lenders.

(d)  Response shall have delivered to Agent such UCC searches and other lien
     searches as Agent may request to evidence compliance with the provisions of
     this Agreement and within 30 days of any such Permitted Acquisition,
     lockbox agreements executed by the Practice with the Agent or a Lender.

Borrowers acknowledge that NationsBank, N.A. ("NationsBank") has advised
Borrowers that NationsBank does not presently intend to approve any acquisitions
for which its approval may be requested under this definition. Borrowers agree
that the inclusion of provisions allowing for such approval in this definition
of Permitted Acquisitions and the inclusion of other provisions in this
Agreement that anticipate possible future acquisitions do not evidence, create
or imply any duty whatsoever on NationsBank's part to approve any such
acquisition.

     "PERMITTED ENCUMBRANCES" means all of the following:

(a)  Encumbrances securing the payment of any of the Obligations.

(b)  Encumbrances securing taxes, assessments, or other governmental charges not
     yet due or which are being contested in good faith by appropriate action
     promptly initiated and diligently conducted, if Borrowers have made reserve
     therefor as required by GAAP.

(c)  Mechanics', repairmen's, materialmen's, warehousemen's, landlords' and
     other like liens arising by operation of law securing accounts that are not
     delinquent.

(d)  Encumbrances on real property used by Borrowers not securing monetary
     obligations, provided that the Encumbrances are of a type customarily
     placed on real property and do not materially impair the value of the
     affected property.

(e)  Pledges or deposits in the ordinary course of business to secure
     nondelinquent obligations under workman's compensation or unemployment laws
     or similar legislation or to secure the performance of leases or contracts
     entered into in the ordinary course of business.

(f)  Purchase Money Security Interests, to the extent permitted by Section 6.1.7
     hereof.

     "PERSON" (whether or not capitalized) means any individual, corporation,
partnership, joint venture, association, joint stock company, trust,
unincorporated organization, government, limited liability company, governmental
agency or political subdivision thereof, or any other form of entity.

     "PLAN" means any employee benefit or other plan established or maintained,
or to which contributions have been made, by Response or any Subsidiary and
covered by Title IV of ERISA or to which Section 412 of the IRC applies.

     "PRACTICE" means an oncology or hematology treatment center or an oncology
or hematology medical practice (including, but not limited to, radiation
oncology medical practices or treatment centers). Whenever in this Agreement
"Practice" is used in describing an acquisition by

                                       10
<PAGE>   12

Response, and if the reference relates to a medical practice, such reference is
to the acquisition of the assets used in the operation of the Practice that can
lawfully be acquired by Response or to the acquisition of an interest in an
entity that owns, as of the time of purchase, only those assets that can be
lawfully acquired by Response.

     "PRICING VALUES" means the Applicable LIBO Rate Margin, the Applicable
Prime Rate Margin and the Applicable Commitment Fee.

     "PRIME RATE" shall be that rate announced by Agent from time to time as its
Prime Rate and is one of several interest rate bases used by Agent. Lenders and
Agent lend at rates both above and below Agent's Prime Rate and Borrowers
acknowledge that the Prime Rate is not represented or intended to be the lowest
or most favorable rate of interest offered by any Lender or Agent.

     "PRIME RATE LOAN" means a Loan for which Response has elected application
of an interest rate based on the Prime Rate.

     "PRO RATA" or "PRO RATA SHARE" of any amount means, with respect to any
Lender at any time, the product of (i) such amount, multiplied by (ii) such
Lender's Percentage at such time of the Credit Facility or Credit Facilities
under which such amount is being paid or advanced or to which such amount
relates; provided however, if at a time of determination there are principal
amounts outstanding under the Revolving Credit Loan, and if any Lender has
failed to fund any unrepaid Revolving Credit Loan that was funded by any other
Lender or Lenders, this apportionment shall be determined according to the
respective total principal amounts of the Revolving Credit Loan held by the
respective Lenders rather than by their Revolving Credit Commitments.

     "PROPERTY" or "PROPERTIES" means any interest in any kind of property,
whether real, personal, or mixed, or tangible or intangible.

     "PROVIDER" means an oncologist, hematologist, radiologist or other medical
doctor whose specialty is complementary to the practice of oncology or
hematology and who performs professional services respecting a Practice that is
either managed by Response or the assets of which are owned by Response.

     "PROVIDER LOANS" means obligations of Providers for amounts owed to
Consolidated Entities resulting from loans advanced to the Providers; provided,
however, that Provider Loans shall not include (i) amounts owed by Providers as
accounts payable for management or service fees that arise in the ordinary
course of business and which are not outstanding more than ninety (90) days, or
(ii) amounts advanced to Providers in the ordinary course of business pursuant
to Service Agreements (including, but not limited to, amounts advanced to
Providers that are used by Providers to pay their accounts payable to Response
for management or service fees described in (i) above), which advances are
secured by security interests in accounts receivable of the Providers which
equal or exceed the amount of the related Provider Loans.

     "PURCHASE MONEY DEBT" means a Liability that is secured by a Purchase Money
Security Interest.

     "PURCHASE MONEY SECURITY INTEREST" means an Encumbrance on specific
equipment (including the Encumbrance arising under a Capital Lease), provided
that (i) the Liability secured by any such Encumbrance shall have arisen at the
time of the acquisition thereof and shall not exceed 100% of the cost of the
equipment to the entity acquiring the same, and (ii) each such

                                       11
<PAGE>   13

Encumbrance shall attach only to the equipment acquired with the proceeds of the
Liability secured thereby.

     "REGULATORY CHANGE" means on or after the Closing Date, the adoption of any
applicable law, rule or regulation, or any change in any applicable law, rule or
regulation, or any change in the interpretation or administration thereof by any
Governmental Authority, central bank or comparable agency charged with the
interpretation or administration thereof, or compliance by the Agent, the
Issuing Bank or any Lender with any request or directive (whether or not having
the force of law) of any such authority, central bank or comparable agency with
respect to establishing reserves for Letters of Credit.

     "REIMBURSEMENT OBLIGATIONS" has the meaning assigned in Section 2.16.2 of
this Agreement.

     "REQUIRED LENDERS" means, at any time, the Lenders owning or holding 66
2/3% or more of the sum of (i) the then aggregate principal amount of the Terms
Loans and the Revolving Credit Commitments then outstanding plus (ii) the then
aggregate Letter of Credit Liabilities; or, if no Loans or Letters of Credits
are then outstanding, the Lenders with 66 2/3% or more of the aggregate of all
Commitments at such time. For purposes of this definition, (i) Required Lenders
must include NationsBank and (ii) the Letter of Credit Liabilities shall be
considered to be owed to the Lenders according to the Revolving Credit
Percentages; provided, however, if at a time of determination there are
principal amounts outstanding under the Revolving Credit Loan, and if any Lender
has failed to fund any unrepaid Loan that was funded by any other Lender or
Lenders, this determination shall be made according to Lenders holding the
required percentage of principal amounts of the Revolving Credit Loan rather
than by the outstanding Revolving Credit Commitments.

     "REVOLVING CREDIT COMMITMENT" means, with respect to any Lender at any
time, the amount set forth under such Lender's name on its signature page hereto
under the caption "Revolving Credit Commitment" or if such Lender has entered
into one or more Assignment and Acceptances, the amount set forth for such
Lender at such time in the register maintained by the Agent pursuant to Section
10.12 as such Lender's "Revolving Credit Commitment" as such amount may be
reduced at or prior to such time pursuant to the terms hereof.

     "REVOLVING CREDIT FACILITY" means the revolving line of credit established
by the Lenders under Article II.

     "REVOLVING CREDIT LOANS" means the revolving credit loans described in
Article II hereof.

     "REVOLVING CREDIT NOTE" means the promissory notes of the Borrowers in
substantially the form of Exhibit 2.3, executed and delivered to the Lenders
with the Revolving Credit Commitments pursuant to Section 2.3 or, in connection
with an Assignment and Acceptance, pursuant to Section 10.12, together with any
amendments, modifications and supplements thereto and restatements thereof, in
whole or in part.

     "REVOLVING CREDIT PERCENTAGE" means, with respect to any Lender at any
time, a fraction (expressed as a percentage) the numerator of which is the
Revolving Credit Commitment of such Lender at such time and denominator of which
is the total Revolving Credit Commitment at such time; provided that if the
Revolving Credit Percentage of any Lender is to be determined after
the Revolving Credit Commitments have been terminated, then such Revolving
Credit Percentage shall be determined immediately prior (and without giving
effect) to such termination.

                                       12
<PAGE>   14

     "SELLER" means the former owner of a Practice that is acquired by a
Consolidated Entity.

     "SELLER DEBT" means a Liability incurred in favor of one or more Sellers
representing part of the purchase price of a Practice.

     "SERVICE AGREEMENT" means one of those service or management agreements now
in effect or hereafter entered into by Response and Providers in connection with
the management of oncology practices and/or IMPACT Centers.

     "SOLVENT" shall mean, as to any Person, that as of any date of
determination, (i) the then fair value of the assets of such Person is (a)
greater than the then total amount of liabilities (including subordinated
liabilities) of such Person and (b) greater than the amount that will be
required to pay such Person's probable liability on such Person's then existing
debts as they become absolute and matured, (ii) such Person's capital is not
unreasonably small in relation to its business, and (iii) such Person has not
incurred and does not intend to incur, or believe or reasonably should believe
that it will incur, debts beyond its ability to pay such debts as they become
due.

     "SUBORDINATED DEBT" means any unsecured Liability that is subordinated as
to payment, liquidation, collection and collection in bankruptcy to the
obligations of Borrowers to Lenders pursuant to subordination documentation in
form and substance acceptable to Agent.

     "SUBSIDIARY" means any present or future corporation, joint venture,
limited liability company, or partnership, at least a majority of whose
outstanding voting stock or other voting securities or interests shall at the
time be owned directly or indirectly by Borrowers.

     "SWINGLINE BORROWING NOTICE" has the meaning assigned in Section 2.17.3(b)
hereof.

     "SWINGLINE LENDER" means AmSouth Bank.

     "SWINGLINE LOAN" means a loan advanced under Section 2.17 hereof, and
funded under the Revolving Credit Loan.

     "SWINGLINE NOTE" means the promissory note of the Borrowers in
substantially the form of Exhibit 2.17.2 hereto executed and delivered to the
Swingline Lender, together with any amendments, modifications and supplements
thereto and restatements thereof.

     "TAXES" means all taxes and assessments, whether general or special,
ordinary or extraordinary, or foreseen or unforeseen, which at any time may be
assessed, levied, confirmed or imposed on the Consolidated Entities or on any of
their properties or assets or any part thereof or in respect of any of their
franchises, businesses, income or profits.

     "TERM LOAN" has the meaning assigned to such term in Section 2.1(a).

     "TERM LOAN COMMITMENT" means, with respect to any Lender at any time, the
amount set forth under such Lender's name on a signature page hereto under the
caption "Term Loan Commitment" or, as such Lender has entered into one or more
Assignment and Acceptances, the amount set forth for such Lender at such time in
the register maintained by the Agent pursuant to Section 10.12 as such Lender's
"Term Loan Commitment," as such amount may be reduced at or prior to such time
pursuant to the terms hereof.

     "TERM LOAN FACILITY" means the term loans extended by the Lenders such
Article II.

                                       13
<PAGE>   15

     "TERM LOAN PERCENTAGE" means, with respect to any Lender at any time, a
fraction (expressed as a percentage) the numerator of which is the Term Loan
Commitment of such Lender at such time and the denominator of which is the total
Term Loan Commitment at such time; provided, that if the Term Loan Percentage of
any Lender is to be determined after the Term Loan Commitments have been
terminated, then such Term Loan Percentage shall be determined immediately prior
(and without giving effect) to such termination.

     "TERM NOTE" means the promissory notes of the Borrowers in substantially
the form of Exhibit 2.3(a), executed and delivered to the Lenders with Term Loan
Commitments pursuant to Section 2.1(a) or, in connection with an Assignment and
Acceptance, pursuant to Section 10.12 together with any amendments,
modifications and supplements thereto and restatements thereof, in whole or in
part.

     "TOTAL COMMITMENTS" means, at any time, the sum of all Commitments at such
time.

     "TOTAL FUNDED DEBT" means all obligations for borrowed money, including,
but not limited to, advances under the Revolving Credit Loan, all Seller Debt,
Subordinated Debt and all Capitalized Leases, whether short-term or long-term,
and including all stated and undrawn amounts under Letters of Credit.

     "TOTAL REVOLVING CREDIT COMMITMENT" means, at any time, the sum of the
Revolving Credit Commitments of all Lenders at such time.

     "TOTAL TERM LOAN COMMITMENT" means, at any time, the sum of the Term Loan
Commitments of all Lenders at such time.

     "UCC" means the Uniform Commercial Code as adopted in Tennessee, as it may
be amended from time to time.

     "UNMATURED DEFAULT" means any event or condition that, but for the giving
of any required notice by Agent and/or the passing of time, would be an Event of
Default hereunder.

     "Y2K PLAN" has the meaning assigned in Section 4.29 hereof.

     "YEAR 2000 COMPLIANT AND READY" means that (A) the Borrowers' and their
Subsidiaries' hardware and software systems with respect to the operation of
their business and their general business plan will (i) handle date information
involving any and all dates before, during and/or after January 1, 2000,
including accepting input, providing output and performing date calculations in
whole or in part, (ii) operate, accurately without interruption on and in
respect of any and all dates before, during and/or after January 1, 2000 and
without any change in performance, and (iii) store and provide date input
information without creating any ambiguity as to the century; and (B) the
Borrowers have developed alternative plans to ensure business continuity in the
event of the failure of any or all of the items in part (A) above.

     1.2   Terms Generally.

     1.2.1 Computations: Accounting Principles. Where the character or amount of
any asset or liability or item of income or expense is required to be
determined, or any consolidation or other accounting computation is required to
be made for the purposes of this Agreement, such determination or calculation,
to the extent applicable and except as otherwise specified in this Agreement,
shall be made in accordance with GAAP. If a change in GAAP after the date of
this

                                       14
<PAGE>   16

Agreement would require a change affecting the calculation of any requirement
under this Agreement, then Agent and Borrowers shall negotiate in good faith for
the amendment of the affected requirements; provided, however, until and unless
such an amendment is agreed upon, the requirements of this Agreement shall
remain as written and compliance therewith shall be determined according to GAAP
as in effect prior to the change.

     1.2.2 Gender and Number. Words used herein indicating, gender or number
shall be read as context may require.

     1.2.3 References Include Successors. References herein to specific Laws,
regulatory bodies, parties or agreements also refer to any successor Laws,
regulatory bodies, and parties, and to all modifications, extensions, renewals
and restatements of agreements.

     1.2.4 References to this Agreement. "Herein," "hereof" and words of similar
import refer to this Agreement as a whole and not to any particular provision
hereof, unless otherwise expressly stated.

     1.2.5 Limitations of Knowledge. Certain representations and warranties are
made herein the Best of Borrowers' Knowledge. These limitations reflect only
Borrowers' special interest in disclosing that no targeted diligence has been
performed as to these matters in connection with this Agreement. Should any
matter so represented or warranted be discovered to be false, then, irrespective
of the knowledge Qualification, the representation or warranty shall be deemed
breached and shall constitute an Event of Default or Unmatured Default
hereunder, as may apply.

     1.3   Participating Entities.

     1.3.1 Attorney-in-Fact. Each Participating Entity, separately and
severally, hereby appoints and designates Response as its agent and
attorney-in-fact to act on behalf of it for all purposes of the Credit
Documents. Response shall have authority to exercise on behalf of each
Participating Entity all rights and powers that Response deems necessary,
incidental or convenient in connection with the Credit Documents, including the
authority to execute and deliver certificates, documents, agreements and other
instruments referred to or provided for in the Credit Documents, request
Revolving Credit Loans and elect interest rate options hereunder, request the
issuance of Letters of Credit, receive all proceeds of Revolving Credit Loans,
give all notices, approvals and consents required or requested from time to time
by the Lenders and take any other actions and steps that each Participating
Entity could take for its own account in connection with the Credit Documents
from time to time, it being the intent of each Participating Entity to grant to
Response plenary power to act on behalf of each Participating Entity in
connection with and pursuant to the Credit Documents. The appointment of
Response as agent and attorney-in-fact for each Participating Entity hereunder
shall be coupled with an interest and be irrevocable so long as any Credit
Document shall remain in effect. Neither the Agent nor the Lenders need obtain
any Participating Entity's consent or approval for any act taken by Response
pursuant to any Credit Document, and all such acts shall bind and obligate
Response and each Participating Entity, jointly and severally. Each
Participating Entity forever waives and releases any claim (whether now or
hereafter arising) against the Lenders based on any claim of Response's lack of
authority to act on behalf of each Participating Entity in connection with the
Credit Documents.

     1.3.2 Liability Limitation. The liability of each Participating Entity with
respect to the Obligations shall be limited to an amount equal to the greater of
(i) $1.00 less than the greatest of (A) the Participating Entity's Net Worth (as
hereinafter defined) as of the end of the most recently concluded fiscal quarter
of the Participating Entity ended on or prior to the date the


                                       15
<PAGE>   17
Participating Entity became a Borrower, (B) the highest Net Worth of the
Participating Entity at the end of any fiscal quarter ending after the
Participating Entity became a Borrower and prior to the earlier of the date of
the commencement of a case under the United States Bankruptcy Code (the
"Bankruptcy Code") involving the Participating Entity or the date enforcement
of this Agreement or any of the other Credit Documents is sought against the
Participating Entity and (C) the Net Worth of the Participating Entity at the
earlier of the date of the commencement of a case under the Bankruptcy Code
involving the Participating Entity or the date enforcement of this Agreement
or any of the other Credit Documents is sought against the Participating Entity;
or (ii) the amount that in a legal proceeding brought within the applicable
limitations period is determined by the final, non-appealable order of a court
having jurisdiction over the issue and the applicable parties to be the amount
of value or benefit given by the Lenders, or received by the Participating
Entity, in exchange for the obligations of the Participating Entity under this
Agreement and the other Credit Documents. As used in this subsection 1.3.2,
"Net Worth" shall mean (x) the fair value of the property of the Participating
Entity from time to time (taking into consideration the value, if any, of rights
of subrogation, contribution and indemnity), minus (y) the total liabilities of
the Participating Entity (including contingent liabilities [discounted in
appropriate instances], but excluding liabilities of the Participating Entity
under this Agreement and the other Credit Documents) from time to time. Should
the liability of any Borrower hereunder for the entire amount of the Obligations
be subject to avoidance or limitation, notwithstanding the contrary agreement
and intention of the parties hereto, under any state or federal fraudulent
conveyance law or any other similar law that may be determined to apply hereto,
the liability of such Borrower shall be deemed limited to the maximum amount for
which the Borrower may be liable without legal impairment.

     1.3.3 Informed Consent. Each Initial Participating Entity (i) acknowledges
that it has had full and complete access to the underlying papers relating to
the Obligations and all other papers executed by any person in connection with
the Obligations, has reviewed them and is fully aware of the meaning and effect
of their contents; (ii) is fully informed of all circumstances that bear upon
the risks of executing this Agreement and the other Credit Documents that a
diligent inquiry would reveal; (iii) has adequate means to obtain from Response
on a continuing basis information concerning Response's financial condition and
is not depending on the Agent or the Lenders to provide such information, now or
in the future; and (iv) agrees that neither the Agent nor the Lenders shall have
any obligation to advise or notify it or to provide it with any data or
information.

     1.3.4 Joint and Several Obligations. Each Initial Participating Entity
hereby agrees that its obligations and liabilities with respect to the
Obligations are joint and several with Response, continuing, absolute and
unconditional (subject to the provisions of subsection (d) of this section).
Without limiting the generality of the foregoing, the obligations and
liabilities of each Initial Participating Entity with respect to the Obligations
shall not be released, discharged, impaired, modified or in any way affected by
(i) the invalidity or unenforceability of any Credit Document, (ii) the failure
of the Agent or the Lenders to give each Initial Participating Entity a copy of
any notice given to Response, (iii) any modification, amendment or supplement of
any obligation, covenant or agreement contained in any Credit Document, (iv) any
compromise, settlement, release or termination of any obligation, covenant or
agreement in any Credit Document, (v) any waiver of payment, performance or
observance by or in favor of Response of any obligation, covenant or agreement
under any Credit Document, (vi) any consent, extension, indulgence or other
action or inaction, or any exercise or non-exercise of any right, remedy or
privilege with respect to any Credit Document, (vii) the extension of time for
payment or performance of any of the Obligations, or (viii) any other matter
that might otherwise be raised in avoidance of, or

                                       16
<PAGE>   18

in defense against an action to enforce, the obligations of each Initial
Participating Entity under this Agreement, the Revolving Credit Loan, the Notes
or any other Credit Document.

     1.3.5 Subrogation and Contribution Agreement. None of the Borrowers will
exercise any rights that it may have or acquire by way of subrogation under this
Agreement or any of the other Credit Documents or the Subrogation and
Contribution Agreement referred to below, by any payment made hereunder or under
any of the other Credit Documents or otherwise, until all the Obligations have
been paid in full and this Agreement has been terminated and is no longer
subject to reinstatement under this Agreement. If any amount shall be paid to a
Borrower on account of any such subrogation rights at any time when all of the
Obligations shall not have been paid in full and this Agreement terminated, such
amount shall be held in trust for the benefit of the Lenders and shall be paid
forthwith to the Lenders to be credited and applied upon the Obligations,
whether matured or unmatured, in accordance with the terms of the Credit
Documents. The Borrowers will not amend or waive any provision of the
Subrogation and Contribution Agreement dated the Closing Date entered into by
the Borrowers nor consent to any departure from such Subrogation and
Contribution Agreement, without having obtained the prior written consent of the
Agent to such amendment, waiver or consent.

     1.3.6 Assumption Agreement. Each Person that is to become after the Closing
Date a Participating Entity shall, at the time it is to become a Participating
Entity, execute and deliver to the Agent, in accordance with the provisions of
Section 3.3, an Assumption Agreement in the form attached hereto as Exhibit
1.3.6 ("Assumption Agreement").


                                    II. LOANS

     Concurrently with the execution of this Agreement, Lenders agree on a
several basis, and not on a joint basis, in accordance with their respective
Commitments, to make the Loans to Borrowers, under the following terms and
conditions:

     2.1 Amount of Revolving Credit Loan. The principal indebtedness of
Borrowers to Lenders having a Revolving Credit Commitment under the Revolving
Credit Loan shall not exceed Seven Million and No/100 Dollars ($7,000,000.00)
less the outstanding principal balance of Swingline Loans outstanding from time
to time.

     2.1(a) Amount of Term Loan. Each Lender having a Term Loan Commitment
severally agrees, subject to and on the terms and conditions of this Agreement,
to make a loan (each, a "Term Loan" and collectively the "Term Loans") to the
Borrowers on the Closing Date in the principal amount not to exceed its Term
Loan Commitment. No Term Loans shall be made at any time after the Closing Date.
To the extent repaid, the Term Loans may not be reborrowed.

     2.2 Use of Proceeds. The proceeds of the Term Loan shall be used by
Borrowers to refinance existing indebtedness and the proceeds of the Revolving
Credit Loan shall be used by Borrowers for (i) Permitted Acquisitions, (ii)
other Capital Expenditures, (iii) the development of IMPACT Centers and of
ancillary services to be offered by Providers, and (iv) Letters of Credit and
working capital purposes.

     2.3 Revolving Credit Loan Notes. Borrowers' obligations under the Revolving
Credit Loan shall be evidenced by Revolving Credit Loan Notes in favor of the
respective Lenders in the form included as Exhibit 2.3 hereto payable to each
Lender for its Revolving Credit Commitment.



                                       17
<PAGE>   19

     2.3(a) Term Loan Notes. Borrowers' obligations under the Term Loan shall be
evidenced by Term Loan Notes in favor of the respective Lenders in the form
included in Exhibit 2.3(a) payable to each Lender for its Term Loan Commitment.

     2.4 Separate Commitments of Lenders. Borrowers acknowledge that each
Lender's commitment to fund its portion of the Loans is made by each Lender
severally, and neither Agent nor any Lender shall be liable for the failure of
another Lender to timely perform under this Agreement.

     2.5 Advances of Loans. Subject to the terms and conditions of this
Agreement, Borrowers may borrow, repay and reborrow Loans under the Revolving
Credit Loan, provided that the outstanding principal balance of the Revolving
Credit Loan shall not at any time exceed the amounts permitted under Section 2.1
above. Loans shall be disbursed as follows:

     2.5.1 Loans Advanced Pursuant to Borrowing Notices.

     2.5.1(a) Applicability. Loans (other than the Swingline Loan) may be LIBOR
Loans, Prime Rate Loans, or a combination thereof, and the funding thereof shall
be subject to this Section 2.5.1.

     2.5.1(b) Borrowing Notices. As long as Borrowers meet the conditions for
funding stated in this Agreement, Response, on behalf of the Borrowers, may
submit requests for Loans ("Borrowing Notices") to Agent. All requests shall be
made in writing (or by telephone, subject to such security procedures as Agent
may require from time to time, provided that all telephonic notices shall be
confirmed by written Borrowing Notices within one (1) Business Day) and shall
specify the proposed disbursement date for the requested Loan; the amount of the
Loan; the purpose of the Loan (characterized in accordance with Section 2.2
above); the type of Loan, i.e., LIBOR Loan or Prime Rate Loan; and if a LIBOR
Loan, the designated Interest Period. Each Borrowing Notice shall irrevocably
obligate Borrowers to accept the Loan requested thereby. Borrowing Notices shall
be in the form of Exhibit 2.5.1(b) hereto or such other form as Agent may from
time to time require.

     2.5.1(c) Funding of Loans. Lenders shall fund their respective portions of
requested Loans on the next following Banking Day after the Banking Day of
Agent's receipt of the Borrowing Notice, in the case of Prime Rate Loans, and on
the second (2nd) Banking Day following the Banking Day of Agent's receipt of the
Borrowing Notice, in the case of LIBOR Loans. All funds shall be disbursed
directly into an account maintained by Response with Agent. Borrowers agree that
if any Lender elects to fund any requested Loan(s) sooner after requested than
is required hereunder, the Lender may nevertheless use the entire response
period allowed hereunder upon receipt of any subsequent request, at the Lender's
sole option.

     2.5.1(d) Prime Rate Loan Limitations. Individual Prime Rate Loans shall be
in the minimum amount of One Hundred Thousand and No/100 Dollars ($100,000.00)
each. Any number of Prime Rate Loans may be outstanding at any one time.

     2.5.1(e) LIBOR Loan Limitations. Individual LIBOR Loans shall be in the
minimum amount of Five Hundred Thousand and No/100 Dollars ($500,000.00) each.
No more than three (3) LIBOR Loans may be outstanding under the Revolving Credit
Loan and no more than three (3) LIBOR Loans may be outstanding under the Term
Loan.

                                       18
<PAGE>   20

     2.5.1(f) Additional Limitation on LIBOR Interest Periods. Notwithstanding
anything to the contrary in this Agreement, if an Unmatured Event of Default or
an Event of Default shall have occurred and be continuing, no additional LIBOR
Loans may be created or continued and no Prime Rate Loan may be converted into a
LIBOR Loan.

     2.5.2 Conversion of Loans. Response, on behalf of the Borrowers, shall have
the right, on prior irrevocable written notice to Agent given two (2) Banking
Days prior to the date of any requested conversion, to convert any Prime Rate
Loan or LIBOR Loan into a Loan of another type, or to continue any LIBOR Loan
for another Interest Period, subject in each case to the following:

     2.5.2(a) Application of Loans. Each conversion shall be effected by
applying the proceeds of the new LIBOR Loan and/or Prime Rate Loan, as the case
may be, to the Loan (or portion thereof) being converted.

     2.5.2(b) Notices of Conversions. Each notice pursuant to this 2.5.2(b)
shall be irrevocable and shall refer to this Agreement and specify the identity
and principal amount of the particular Loan that Response requests be converted
or continued; if such notice requests conversion, the date of such conversion
(which shall be a Business Day); and if a Loan is to be converted to a LIBOR
Loan or a LIBOR Loan is to be continued, the Interest Period with respect
thereto. No LIBOR Loan shall be converted at any time other than at the end of
the Interest Period applicable thereto, except in accordance with Section 2.11
hereof. Conversion notices shall be in the form attached as Exhibit 2.5.1(b)
hereto.

     2.5.3 Absence of Election. If Response fails to give Agent notice to
continue any LIBOR Loan for a subsequent period, such LIBOR Loan (unless repaid)
shall automatically be converted into a Prime Rate Loan. If Response fails to
specify in any Borrowing Notice the type of borrowing or, in the case of a LIBOR
Loan, the applicable Interest Period, Response will be deemed to have requested
a Prime Rate Loan.

     2.5.4 Implied Representations Upon Request for Loan. Upon making any
request for any Loan, Borrowers shall be deemed to have warranted to Agent and
Lenders that all conditions to funding set forth in Article III hereof are
satisfied.

     2.5.5 Advance Not Waiver. Any Lender's making of any Loan that it is not
obligated to make under any provision of Article III hereof or any other
provision hereof shall not be construed as a waiver of the Lenders' right to
withhold future Loans, declare an Event of Default, or otherwise demand strict
compliance with this Agreement, acting through Agent as permitted by the terms
hereof.

     2.5.6 Draws by Debit Memorandum. Agent may cause Lenders to draw amounts
that may be available under the Revolving Credit Loan to pay any Obligation that
is not otherwise timely paid.

     2.6 Interest. Interest shall accrue on each Loan as follows:

     2.6.1 Prime Rate Loans. Interest shall accrue on each Prime Rate Loan at an
annual rate equal to the Prime Rate plus the Applicable Prime Rate Margin, said
rate to change contemporaneously with any change in the Prime Rate.

                                       19
<PAGE>   21

     2.6.2 LIBOR Loans. Interest shall accrue on each LIBOR Loan at a rate equal
to the LIBO Rate for the selected Interest Period plus the Applicable LIBO Rate
Margin.

     2.6.3 Additional Interest on LIBOR Loans. In addition to the interest
described above, Borrowers shall pay to Lenders, if and so long as Lenders shall
be required under regulations of the Board of Governors of the Federal Reserve
System to maintain reserves with respect to liabilities or assets consisting of
or including LIBOR Liabilities, additional interest on the unpaid principal
amount of each LIBOR Loan, from the date of such advance until said principal
amount is paid in full, at an interest rate per annum equal at all times to the
remainder obtained by subtracting (i) the LIBO Rate for the Interest Period from
(ii) the rate obtained by dividing the LIBO Rate by a percentage equal to 100%
minus the LIBO Rate Reserve Percentage for such Interest Period. This additional
interest shall be payable on each date on which interest is payable. The amount
of additional interest shall be determined by each Lender, who shall notify
Borrowers and Agent thereof and whose determination shall be conclusive, absent
manifest error.

     2.6.4 Calculation of Interest. Interest for both Prime Rate Loans and LIBOR
Loans shall be computed on the basis of a 360-day year counting the actual
number of days elapsed. Interest shall accrue on the Business Day a Loan is
extended and shall accrue through the Banking Day prior to the Banking Day on
which it is repaid.

     2.6.5 Default Rate. Notwithstanding the foregoing, upon the occurrence of
an Event of Default and during the continuation of such Event of Default,
interest shall be charged at the Default Rate, regardless of whether Lenders
have elected to exercise any other remedies available to Lenders, including,
without limitation, acceleration of the maturity of the outstanding principal of
the Revolving Credit Loan or the Term Loan, as the case may be. All such
interest shall be paid without demand on the Interest Payment Dates applicable
to Prime Rate Loans.

     2.6.6 Payment of Interest. Interest for Prime Rate Loans and LIBOR Loans
shall be due and payable in arrears, without notice, on each Interest Payment
Date.

     2.6.7 Usury Savings Provision. It is the intention of the parties that all
charges under or in connection with this Agreement and the Obligations, however
denominated, and including (without limitation) all interest, commitment fees,
late charges and loan charges, shall be limited to the Maximum Lawful Amount.
Such charges hereunder shall be characterized and all provisions of the Credit
Documents shall be construed as to uphold the validity of charges provided for
therein to the fullest possible extent. Additionally, all charges hereunder
shall be spread over the full permitted term of the Obligations for the purpose
of determining the effective rate thereof to the fullest possible extent,
without regard to prepayment of or the right to prepay the Obligations. If for
any reason whatsoever, however, any charges paid or contracted to be paid in
respect of the Obligations shall exceed the Maximum Lawful Amount, then, without
any specific action by Lenders, Agent or Borrowers, the obligation to pay such
interest and/or other charges shall be reduced to the Maximum Lawful Amount in
effect from time to time and any amounts collected by Lenders that exceed the
Maximum Lawful Amount shall be applied to the reduction of the principal balance
of the Obligations and/or refunded to Borrowers so that at no time shall the
interest or loan charges paid or payable in respect of the Obligations exceed
the Maximum Lawful Amount. This provision shall control every other provision
herein and in any and all other agreements and instruments now existing or
hereafter arising between Borrowers and Lenders with respect to the Obligations.

     2.7 Alternate Rate of Interest if LIBOR Unavailable. In the event, and on
each occasion, that on the date of commencement of any Interest Period for a
LIBOR Loan, a Lender shall have

                                       20
<PAGE>   22

determined (i) that dollar deposits in the amount of the requested principal
amount of such LIBOR Loan are not generally available in the London Interbank
Market; (ii) that the rate at which such dollar deposits are being offered will
not adequately and fairly reflect the cost to such Lender of making or
maintaining such LIBOR Loan during such Interest Period; or (iii) that
reasonable means do not exist for ascertaining the LIBO Rate, such Lender shall,
as soon as practicable thereafter, give written or telephonic notice of such
determination to Borrowers. In the event of any such determination, any request
by Borrowers for a LIBOR Loan under this Agreement shall, until the
circumstances giving rise to such notice no longer exist, be deemed to be a
request for a Prime Rate Loan. Each determination by such Lender hereunder shall
be conclusive absent manifest error.

     2.8   Change in Circumstances.

     2.8.1 Imposition of Requirements. Notwithstanding any other provision
herein, if after the date of this Agreement any change in applicable Laws or in
the interpretation or administration thereof by any Governmental Authority
charged with the interpretation or administration thereof (whether or not having
the force of Law) shall change the basis of taxation of payments to a Lender
under any LIBOR Loan made by the Lender or any other fees or amounts payable
hereunder (other than taxes imposed on the overall net income, gross receipts or
added value of a Lender by the country in which the Lender is located, or by the
jurisdiction in which a Lender has its principal office, or by any political
subdivision or taxing authority therein), or shall impose, modify or deem
applicable any reserve requirement, special deposit, insurance charge (including
FDIC insurance on LIBOR Liabilities) or similar requirement against assets of,
deposits with or for the account of, or credit extended by, a Lender or shall
impose on a Lender or the London Interbank Market any other condition affecting
this Agreement or LIBOR Loans made by a Lender, and the result of any of the
foregoing shall be to increase the cost to the Lender of making or maintaining
its LIBOR Loan or to reduce the amount of any sum received or receivable by a
Lender hereunder (whether of principal, interest or otherwise) in respect
thereof by an amount deemed by the affected Lender to be material, then
Borrowers will pay to such Lender such additional amount or amounts as will
compensate the Lender for such additional costs of reduction.

     2.8.2 Other Changes. If either (i) the introduction of, or any change in,
or in the interpretation of, any United States or foreign Law; or (ii)
compliance with any directive, guidelines or request from any central bank or
other United States or foreign Governmental Authority (whether or not having the
force of law) promulgated or made after the date hereof, affects or would affect
the amount of capital required or expected to be maintained by a Lender (or any
lending office of a Lender) or any corporation directly or indirectly owning or
controlling a Lender (or any lending office of a Lender) based upon the
existence of this Agreement, and the Lender shall have determined that such
introduction, change or compliance has or would have the effect of reducing the
rate of return on the Lender's capital or on the capital of such owning or
controlling corporation as a consequence of its obligations hereunder (including
its commitment) to a level below that which the Lender or such owning or
controlling corporation could have achieved but for such introduction, change or
compliance (after taking into account that Lender's policies or the policies of
such owning or controlling corporation, as the case may be, regarding capital
adequacy) by an amount deemed by the Lender (in its sole discretion) to be
material, then, from time to time, Borrowers shall pay to the Lender such
additional amount or amounts as will compensate the Lender for such reduction
attributable to making, funding and maintaining its commitment and Loans
hereunder.

                                       21
<PAGE>   23

     2.8.3 Computation of Amounts. A certificate of a Lender setting forth the
basis and method of computation of such amount or amounts specified in Sections
2.11.1 and 2.11.2 hereof as shall be necessary to compensate the Lender (or its
participating banks) as specified above, as the case may be, shall be delivered
to Borrowers and shall be conclusive absent manifest error; provided however,
that Borrowers shall be responsible for compliance herewith and the payment of
increased costs only to the extent that (i) any change in Laws giving rise to
increased costs occurs after the date of this Agreement; and (ii) the Lender
gives notice of the change giving rise to increased costs within one hundred
eighty (180) Business Days after the Lender has, or with reasonable diligence
should have had, knowledge of the change, or else Lender can only collect costs
from and after the date of the notice. Subject to the foregoing, Borrowers shall
pay the affected Lender the amount shown as due on any such certificate within
ten (10) Business Days after its receipt of such certificate.

     2.8.4 No Duty to Contest. The protection of this Section 2.8 shall be
available to a Lender regardless of any possible contention of invalidity or
inapplicability of the Law or condition that shall have been imposed. Should a
Lender assess any charge to Borrowers under this Section 2.8, and provided that
Borrowers pay the assessment to the Lender, Borrowers may thereafter undertake,
at Borrowers' own expense any contest of the matters giving rise to the charge
that may, in the opinion of Borrowers' independent counsel issued to the
affected Lender, and concurred in by counsel to the Lender, have a reasonable
chance of success, provided further that the contest would not require the
assertion of any position contrary to a position taken by the Lender generally
with taxing authorities or any other involved parties and that there does not
exist any other circumstance that would disadvantage the Lender in the event of
such contest, as the affected Lender may determine in its discretion. The
affected Lender shall offer reasonable participation to Borrowers for the
purpose of enabling Borrowers to pursue the contest of such issue, with all
expenses, including fees and expenses of the affected Lender's counsel, to be
paid by Borrowers.

     2.9 Change in Legality of LIBOR Loans. Notwithstanding anything to the
contrary herein contained, if any change in any Law or in interpretation thereof
by any Governmental Authority charged with the administration or interpretation
thereof shall make it unlawful for a Lender to make or maintain any LIBOR Loan
or to give effect to its obligations as contemplated hereby, then, by written
notice to Borrowers, the Lender may (i) declare that LIBOR Loans will not
thereafter be made by the Lender hereunder, whereupon Borrowers shall be
prohibited from requesting LIBOR Loans from the Lender hereunder unless such
declaration is subsequently withdrawn; and (ii) require that all outstanding
LIBOR Loans made by it be converted to Prime Rate Loans, in which event (a) all
such LIBOR Loans shall be automatically converted to Prime Rate Loans (but
without imposition of any additional charge that would normally become due under
Section 2.8 hereof) as of the effective date of such notice, and (b) all
payments and prepayments of principal that would otherwise have been applied to
repay the converted LIBOR Loans shall instead be applied to repay the Prime Rate
Loans resulting from the conversion of such LIBOR Loans. For purposes of this
Section 2.9, a notice to Borrowers by the Lender pursuant to (a) above shall be
effective, if lawful, on the last day of the then current Interest Period; in
all other cases, such notice shall be effective on the date of receipt by
Borrowers.

     2.10 Principal Repayment. All remaining principal outstanding under the
Revolving Credit Loan shall become due on the Maturity Date or the earlier
acceleration of the Revolving Credit Loan in accordance with the terms of this
Agreement. Except to the extent due or made sooner pursuant to the provisions of
this Agreement, the Borrowers will repay the aggregate principal of the Term
Loans in the amounts (as such amount may be reduced as provided in this
Agreement) and on the dates set forth below:

                                       22
<PAGE>   24
<TABLE>
<CAPTION>
          Date                    Quarterly Payment
          ----                    -----------------
     <S>                          <C>
     July 1, 1999                     $1,250,000
     October 1, 1999                   1,250,000
     January 1, 2000                   1,250,000
     April 1, 2000                     1,250,000
     July 1, 2000                      1,500,000
     October 1, 2000                   1,500,000
     January 1, 2001                   1,500,000
     April 1, 2001                     1,500,000
     July 1, 2001                      1,500,000
     October 1, 2001                   1,500,000
     January 1, 2002                   1,500,000
     April 1, 2002                     1,500,000
     June 10, 2002                  Balance Due in Full
</TABLE>


     To the extent not previously paid, the aggregate outstanding principal
amount of the Term Loans shall be due and payable on the Maturity Date. During
the continuance of any Event of Default, all prepayments shall be applied,
first, to the Term Loans, second, upon payment in full of the Term Loans, to the
Swing Line Loans, and third, after payment in full of the Swing Line Loans, to
the Revolving Credit Loans. In the absence of an Event of Default, voluntary
prepayments pursuant to this Agreement shall be applied as the Borrowers
determine. Revolving Credit Loans and Swing Line Loans (but not Term Loans)
prepaid pursuant to this Agreement may be reborrowed, subject to the terms and
conditions of this Agreement. Each prepayment of the Term Loans made pursuant to
this Agreement shall be applied to reduce the aggregate outstanding principal
amount of the Term Loans, ratably among the Lenders holding Term Loans in
proportion to the principal amount held by each, with each such reduction to be
applied to each scheduled principal payment to reduce the scheduled payment on
the Term Loans due under this Section on a pro rata basis across maturities.
Each prepayment of the Revolving Credit Loans made pursuant to this Agreement
shall be applied to reduce the aggregate outstanding principal amount of the
Revolving Credit Loans, ratably among the Lenders holding Revolving Credit Loans
in proportion to the principal amount held by each.

     2.11 Prepayment of LIBOR Loans.

     2.11.1 Notice of LIBOR Loan Prepayment. Borrower may, upon two (2) Banking
Days' prior written notice to Agent, and upon payment of all applicable premiums
set forth in Section 2.11.3 hereof, prepay any outstanding LIBOR Loans prior to
any Interest Payment Date for such LIBOR Loans, in whole or in part. Each notice
of prepayment of any LIBOR Loan shall specify the date and amount of such
prepayment and shall be irrevocable.

     2.11.2 Amount of LIBOR Loan Prepayment. Each partial prepayment of any
LIBOR Loan shall be in an aggregate principal amount which is the lesser of (i)
the then outstanding principal balance of the one or more LIBOR Loans to be
prepaid, or (ii) Five Hundred Thousand and No/100 Dollars ($500,000.00) or an
integral multiple thereof. Interest on the amount prepaid accrued to the
prepayment date shall be paid on such date.

     2.11.3 LIBOR Loan Prepayment Premium. Upon prepayment of any LIBOR Loan on
a date other than the relevant Interest Payment Date for such borrowing,
Borrowers shall pay to Lenders, in addition to all other payments then due and
owing Lenders, premiums which shall be equal to an amount, if any, reasonably
determined by Agent to be the difference between the rate


                                       23
<PAGE>   25

of interest then applicable to the relevant LIBOR Loan and the yield Lenders
would receive upon reinvestment of so much of the relevant LIBOR Loans as is
prepaid for the remainder of the term of the relevant LIBOR Loan or Loans.
Anything in this Section 2.11.3 to the contrary notwithstanding, the premiums
payable upon any such prepayment shall not exceed the amount, if any, determined
by Agent to be the difference between the rate of interest then applicable to
the relevant LIBOR Loan and the yield that Lenders could receive upon
reinvestment in the "Floor Reinvestment" of so much of the relevant LIBOR Loan
as is prepaid for the remainder of the term of the relevant LIBOR Loan. For
purposes hereof, "Floor Reinvestment" shall mean an investment for the time
period from the date of such prepayment to the end of the relevant Interest
Period applicable to such LIBOR Loan at an interest rate per annum equal to the
federal funds "offered" rate as published in the Wall Street Journal on the date
of such prepayment. All determinations, estimates, assumptions, allocations and
the like required for the determination of such premiums shall be made by Agent
in good faith and shall be presumed correct absent manifest error.

     2.12 Prepayment of Prime Rate Loans. Borrower may at any time prepay any
outstanding Prime Rate Loans prior to the Maturity Date in whole or in part
without premium or penalty.

     2.13 Fixed Commitment Fees. Upon the execution of this Agreement, Borrowers
shall pay commitment fees to AmSouth and the other Lenders, in the amounts
previously agreed to by the Borrowers and the Lenders. These commitment fees are
not refundable or proratable.

     2.14 Periodic Commitment Fee Based on Use of Facilities. Borrowers shall
pay to Agent for distribution to Lenders Pro Rata an additional commitment fee
for the unused portion of the Revolving Credit Loan. This fee shall be
determined by applying the Applicable Commitment Fee to the average daily unused
balance of the Revolving Credit Loan. The commitment fee shall be paid in
arrears on the first day of each January, April, July and October, commencing on
July 1, 1999. This commitment fee is not refundable or proratable.

     2.15 Agent's Fee. On the Closing Date, and on each subsequent anniversary
thereof excepting only an anniversary corresponding to the Maturity Date,
Borrowers shall pay to Agent, for its own account, a fee in such amount as shall
be agreed to from time to time.

     2.16 Letters of Credit. Subject to the terms and conditions of this
Agreement, Lenders' respective Revolving Credit Commitments may be utilized,
upon the request of Response, on behalf of the Borrowers, for the issuance by
the Issuing Bank of letters of credit (the "Letters of Credit") for the account
of Borrowers for uses that would be permitted for the Revolving Credit Loan;
provided that in no event shall (i) the aggregate amount of all stated and
undrawn amounts under Letters of Credit (the "Letter of Credit Liabilities"),
together with the aggregate principal amount of the Loans advanced under the
Revolving Credit Loan, exceed the amount stated in Section 2.1 hereof, or (ii)
the expiration date of any Letter of Credit extend beyond the Maturity Date
applicable to the Revolving Credit Loan. The following additional provisions
shall apply to Letters of Credit:

     2.16.1 Procedure for Issuance. Borrower shall give Agent at least three (3)
Business Days' irrevocable prior notice (effective upon receipt) specifying (i)
the Business Day (which shall be no later than thirty (30) days preceding the
Maturity Date) each Letter of Credit is to be issued and (ii) which Lender is
to be the Issuing Bank and describing in reasonable detail the proposed terms of
such Letter of Credit (including its beneficiary) and the nature of the
transactions or obligations proposed to be supported. On the same day that the
Agent receives such notice for issuance of Letters of Credit, the Agent shall
notify the Lender requested by the Borrowers to


                                       24
<PAGE>   26

issue a Letter of Credit and the other Lender or Lenders of receipt of such
notice for issuance of Letters of Credit. If the Lender requested by the
Borrowers to issue the Letter of Credit is a Lender other than AmSouth, and such
Lender declines to issue such Letter of Credit, or if the Borrowers fail to
specify the Lender that is to issue the Letter of Credit, AmSouth shall issue
the Letter of Credit requested by the Borrowers and shall be the Issuing Bank
with respect thereto. The Issuing Bank (whether the Lender requested by the
Borrowers to issue the Letter of Credit or AmSouth) shall issue the Letter of
Credit and will make available to the beneficiary thereof the original of such
Letter of Credit, as directed by Response. Response shall be the account party
for each Letter of Credit, including Letters of Credit issuable to a beneficiary
having a claim or potential claim against a Subsidiary of Response.

     2.16.2 Participation Among Lenders. On each day during the period
commencing with the issuance by the Issuing Bank of any Letter of Credit and
until such Letter of Credit shall have expired or been terminated or, if drawn
upon, until the resulting obligations of reimbursement (the "Reimbursement
Obligations") have been satisfied in full by Borrowers (whether by a borrowing
under this Agreement or otherwise), the Revolving Credit Commitment of each
Lender shall be deemed to be utilized for all purposes of this Agreement
(including, but not limited to, the calculation of availability and of the
nonuse fee) in an amount equal to such Lender's Pro Rata Share of the Letter of
Credit Liabilities associated with such Letter of Credit. Each Lender (other
than the Issuing Bank) agrees that, upon the issuance of any Letter of Credit,
it shall automatically be deemed to have acquired a participation in the Issuing
Bank's liability under such Letter of Credit in an amount equal to such Lender's
Pro Rata Share of such liability, and each Lender (other than the Issuing Bank)
thereby shall absolutely, unconditionally and irrevocably assume, as primary
obligor and not as surety, and shall be unconditionally obligated to the Issuing
Bank to pay and discharge when due, its Pro Rata Share of the Issuing Bank's
liability under such Letter of Credit.

     2.16.3 Reimbursement Obligation. Upon receipt from the beneficiary of any
Letter of Credit of any demand for payment under such Letter of Credit, the
Issuing Bank shall promptly notify Agent (if AmSouth is not the Issuing Bank)
and Response of the amount to be paid by the Issuing Bank as a result of such
demand and the date on which payment is to be made by the Issuing Bank to such
beneficiary in respect of such demand. Borrowers hereby unconditionally agree to
pay and reimburse Agent for the account of the Issuing Bank and the other
Lenders Pro Rata with respect to the amount of each demand for payment under
such Letter of Credit at or prior to the date on which payment is to be made by
the Issuing Bank to the beneficiary under such Letter of Credit, without
presentment, demand, protest or other formalities of any kind. Any amounts not
so paid or borrowed as set forth in Section 2.16.4 below shall bear interest at
the rate(s) specified in the documents relating to the issuance of the Letter of
Credit (the "Letter of Credit Documents") or, if higher, at the rate(s)
specified on the Notes (including the Default Rate, if applicable).

     2.16.4 Means of Reimbursement. Forthwith upon its receipt of a notice
referred to in Section 2.16.3 hereof, Response shall advise Agent whether or not
Response, on behalf of Borrowers, intends to obtain a Loan to finance its
obligation to reimburse the Issuing Bank for the amount of the related demand
for payment and, if it does, submit a notice of such borrowing as provided in
this Agreement. In the event that Response fails to so advise Agent, and if
Response fails to reimburse the Issuing Bank for a demand for payment under a
Letter of Credit by the date of such payment, Agent shall give each Lender
prompt notice of the amount of the demand for payment, specifying such Lender's
Pro Rata Share of the amount of the related demand for payment, and Borrowers
shall be deemed in default hereunder for breaching Section 2.16.3 above.

                                       25
<PAGE>   27

     2.16.5 Payments by Lenders. Each Lender (other than the Issuing Bank) shall
pay to Agent for the account of the Issuing Bank in Dollars and in immediately
available funds, such Lender's Pro Rata Share of any payment under a Letter of
Credit upon notice by Agent to such Lender requesting such payment and
specifying such amount as provided in Section 2.16.4. Each such Lender's
obligation to make such payments to Agent for the account of the Issuing Bank
under this Section 2.16.5, and the Issuing Bank's right to receive the same,
shall be absolute and unconditional and shall not be affected by any
circumstance whatsoever, including the failure of any other Lender to make its
payment under this Section 2.16.5, the financial condition of Borrowers, the
existence of any Unmatured Default or Event of Default or the termination of the
Revolving Credit Commitments. Each such payment to the Issuing Bank shall be
made without any offset, abatement, withholding or reduction whatsoever;
provided, nothing contained in the foregoing shall limit the Issuing Bank's
liability for its gross negligence or willful misconduct in improperly honoring
a draft drawn under a Letter of Credit.

     2.16.6 Settlement Among Lenders. Upon the making of each payment by a
Lender to the Issuing Bank pursuant to Section 2.16.5 above in respect of any
Letter of Credit, such Lender shall, automatically and without any further
action on the part of Agent, the Issuing Bank or such Lender, acquire (i) a
participation in any amount equal to such payment in the Reimbursement
Obligation owing to the Issuing Bank by Borrowers under this Agreement and under
the Letter of Credit Documents relating to such Letter of Credit and (ii) a
participation in a percentage equal to such Lender's Pro Rata Share in any
interest or other amounts payable by Borrowers under such Letter of Credit
Documents and the other Credit Documents in respect of such Reimbursement
Obligation. Upon receipt by the Issuing Bank from or for the account of
Borrowers of any payment in respect of any Reimbursement Obligation or any such
interest or other amount (including by way of set-off or application of proceeds
of any collateral security) the Issuing Bank shall promptly pay to Agent for the
account of each Lender who shall have previously assumed a participation in such
payment under clause (ii) above, such Lender's Pro Rata Share of such payment,
each such payment by the Issuing Bank to be made in the same money and funds in
which received by the Issuing Bank. In the event any payment received by the
Issuing Bank and so paid to Lenders is rescinded or must otherwise be returned
by the Issuing Bank, each Lender shall, upon the request of the Issuing Bank
(through Agent), repay to the Issuing Bank (through Agent) the amount of such
payment paid to such Lender, with interest at the rate specified in Section
2.16.10.

     2.16.7 Letter of Credit Fee. Borrowers shall pay to Agent for the account
of each Lender a letter of credit fee in respect of each Letter of Credit on the
daily average undrawn face amount of such Letter of Credit for the period from
and including the date of issuance of such Letter of Credit to and including the
date such Letter of Credit is drawn in full, expires or is terminated (such fee
to be non-refundable, to be paid in arrears on the first day of each calendar
quarter and on the Maturity Date applicable to the Revolving Credit Loan and to
be calculated, for any day, after giving effect any payments made under such
Letter of Credit on such day) in an amount equal to the Applicable LIBO Rate
Margin(s) in effect during the relevant period. In addition, for each Letter of
Credit that is issued (and all renewals thereof), the Borrowers agree to pay to
the Agent in advance, for the sole account of the Issuing Bank, an issuance or
renewal fee, as the case may be, equal to one-eighth of one percent (1/8%) per
annum on the stated amount of the Letter of Credit being issued or renewed. Such
fee shall be payable in advance on the date of issuance or renewal, as the case
may be. All calculations of Letter of Credit fees shall be based on a 360 day
year counting the actual number of elapsed days.

                                       26
<PAGE>   28

     2.16.8 Letter of Credit Information. Upon the request of any Lender from
time to time, the Issuing Bank shall deliver any information reasonably
requested by such Lender with respect to each Letter of Credit then outstanding.

     2.16.9 Conditions Relating to Letters of Credit. The issuance by the
Issuing Bank of each Letter of Credit shall be subject, in addition to the
conditions precedent set forth in Article III hereof (as though the issuance of
the Letter of Credit were the making of a Loan), to the conditions precedent
that (i) such Letter of Credit shall be in such form, contain such terms and
support such transactions as shall be satisfactory to the Issuing Bank
consistent with its then current practices and procedures with respect to
letters of credit of the same type and (ii) Borrowers shall have executed and
delivered such applications, agreements and other instruments relating to such
Letter of Credit as the Issuing Bank shall have reasonably requested consistent
with its then current practices and procedures with respect to letters of credit
of the same type; provided that in the event of any conflict between any such
application, agreement or other instrument and the provisions of this Agreement,
the provisions of this Agreement shall control.

     2.16.10 Payments Among Lenders. In the event that any Lender fails to pay
any amount required to be paid pursuant to this Section 2.16 when due, such
Lender shall pay interest to the Issuing Bank (through Agent) on such amount
from and including such due date to but excluding the date such payment is made
(i) during the period from and including such due date to but excluding the date
three Business Days thereafter, at a rate per annum equal to the federal funds
rate (as in effect from time to time as determined by Agent) and (ii)
thereafter, at a rate per annum equal to the Prime Rate plus 2.0%.

     2.16.11 Modifications. The issuance by the Issuing Bank of any modification
or supplement to any Letter of Credit shall be subject to the same conditions
applicable under this Section 2.16 to the issuance of new Letters of Credit, and
no such modification or supplement shall be issued unless either (x) the
respective Letter of Credit as affected by such action would have complied with
such conditions had it originally been issued in such modified or supplemented
form or (y) each Lender shall have consented to such modification or supplement.

     2.16.12 Absolute Obligations of Borrowers. The obligations of Borrowers
under this Section 2.16 shall be unconditional and absolute and shall not be
affected, modified or impaired, upon the happening at any time or time to time
of any event, including any of the following, whether or not with notice to or
the consent of Borrowers:

     2.16.12(a) the compromise, settlement, release, modification,. amendment
(whether material or otherwise) or termination of any or all of the obligations,
conditions covenants or agreements of any Person in respect of any of the Credit
Documents;

     2.16.12(b) the occurrence, or the failure by Agent, any Lender or any other
Person to give notice to Borrowers of the occurrence, of any Event of Default or
any default under any of the other Credit Documents;

     2.16.12(c) the waiver of the payment, performance or observance of any of
the obligations, conditions, covenants or agreements of any Person contained in
any of the Credit Documents;

     2.16.12(d) the extension of the time for performance of any other
obligations, covenants or agreements of any Person under or arising out of any
of the Credit Documents;

                                       27
<PAGE>   29

     2.16.12(e) the taking or the omission of any of the actions referred to in
any of the Credit Documents;

     2.16.12(f) any failure, omission or delay on the part of Agent, any Lender,
Borrowers or the beneficiary of any Letter of Credit to enforce, assert or
exercise any right, remedy, power or privilege conferred by this Agreement or
any of the Credit Documents, or any other act or acts on the part of Agent, any
Lender, Borrowers or the beneficiary of any Letter of Credit;

     2.16.12(g) the voluntary or involuntary liquidation, dissolution, sale or
other disposition of all or substantially all the assets of, the marshaling of
assets and liabilities, receivership, insolvency, bankruptcy, assignment for the
benefit of creditors, reorganization, arrangement, composition with creditors or
readjustment of, or other similar proceedings which affect, Borrowers or any
other party to any of the Credit Documents;

     2.16.12(h) any lack of validity or enforceability of this Agreement, any
Letter of Credit or any other Credit Document, or any allegation of invalidity
or unenforceability or any contest of such validity or enforceability;

     2.16.12(i) the existence of any claim, set-off, defense or other right
which Borrowers may have at any time against Agent, any Lender or any
beneficiary or any transferee of any Letter of Credit (or any persons or
entities for whom the Lender or any such beneficiary or transferee may be
acting), or any other Person, whether in connection with this Agreement or any
of the other Credit Documents or any of the transactions contemplated by any
Credit Document or any unrelated transaction;

     2.16.12(j) any statement in any certificate or any other document presented
under any Letter of Credit proving to be forged, fraudulent, invalid or
insufficient in any respect or any such statement being untrue or inaccurate in
any respect whatsoever;

     2.16.12(k) payment by the Issuing Bank under any Letter of Credit against
presentation of a demand or certificate which does not comply with the terms of
such Letter of Credit;

     2.16.12(1) the release or discharge by operation of law of Borrowers from
the performance or observance of any obligation, covenant or agreement contained
in any of the Credit Documents; or

     2.16.12(m) any other circumstance or happening whatsoever, whether or not
similar to any of the foregoing.

     2.16.13 Indemnification. Without affecting Borrowers' liability under any
other provision of this Agreement, Borrowers agree to indemnify each of the
Issuing Bank, Agent and Lenders and their respective affiliates, directors,
officers, employees, attorneys and agents from, and hold each of them harmless
against, any and all losses, liabilities, damages or expenses incurred by any of
them in connection with or by reason of any actual or threatened investigation,
litigation or other proceeding (including, in respect of the Issuing Bank and
Agent, any such investigations, litigation or other proceeding between the
Issuing Bank or Agent and any Lender) relating to (a) the execution and delivery
of any Letter of Credit; (b) the use of the proceeds of any drawing under any
Letter of Credit; or (c) the transfer or substitution of, or payment or failure
to pay under, any Letter of Credit, including the reasonable fees and
disbursements of counsel incurred in connection with any such investigation,
litigation or other proceeding, but excluding damages, losses, liabilities or
expenses to the extent, but only to the extent, incurred by reason of the
willful

                                       28
<PAGE>   30

misconduct or gross negligence of the Issuing Bank in determining whether a
document presented under any Letter of Credit complies with the terms of such
Letter of Credit. It shall not be a condition to any such indemnification that
the Issuing Bank, Agent or any Lender shall be a party to any such
investigations, litigation or other proceeding. Nothing in this Paragraph 2.16
is intended to limit Borrowers' payment obligations under this Agreement.

     2.16.14 Assumption of Risk. Borrowers assume all risks of the acts or
omissions of any beneficiary of any Letter of Credit with respect to the use of
the Letter of Credit. None of Agent, any Lender nor any of their respective
affiliates, officers, directors, employees, attorneys or agents shall be liable
or responsible for: (a) the use which may be made of the Letter of Credit or for
any acts or omissions of any beneficiary of any Letter of Credit in connection
with such Letter of Credit; (b) the validity, sufficiency or genuineness of
documents presented to the Issuing Bank, or of any endorsement on such
documents, even if such documents should in fact prove to be in any or all
respects invalid, insufficient, fraudulent or forged; (c) payment by the Issuing
Bank against presentation of documents which do not comply with the terms of any
Letter of Credit, including failure of any documents to bear any reference or
adequate reference to such Letter of Credit; or (d) any other circumstances
whatsoever in making or failure to make payment under any Letter of Credit;
provided that Borrowers shall have a claim against the Issuing Bank to the
extent, but only to the extent, of any direct, as opposed to consequential,
damages suffered by Borrowers which Borrowers prove were caused by the Issuing
Bank's willful misconduct or gross negligence in determining whether a document
presented under any Letter of Credit complies with the terms of such Letter of
Credit. In furtherance and not in limitation of the foregoing, the Issuing Bank
may accept documents that appear on their face to be in order, without
responsibility for further investigation, regardless of any notice or
information to the contrary.

     2.16.15 Reserves. The Borrowers acknowledge that each Issuing Bank will be
required by applicable rules and regulations of the Federal Reserve Board to
maintain reserves for its liability to honor draws made pursuant to a Letter of
Credit notwithstanding the obligation of the Lenders for a participation in such
Letter of Credit Liabilities. The Borrowers agree to reimburse the Issuing Bank
promptly for all additional costs incurred by reason of any Regulatory Change
that the Issuing Bank may hereafter incur solely by reason of its acting as
issuer of the Letters of Credit and its being required to reserve for such
liability, it being understood by the Borrowers that other interest and fees
payable under this Agreement do not include compensation of the Issuing Bank for
such reserves. Each Issuing Bank shall furnish to the Borrowers, at the time of
such Issuing Bank's demand for payment of such additional costs, the computation
of such additional cost, which shall be conclusive absent demonstrable error,
provided that such computations are made on a reasonable basis. The Borrowers
shall pay to the Issuing Bank administrative and other fees, if any, in
connection with the Letters of Credit in such amounts and at such times as the
Issuing Bank and the Borrowers shall agree from time to time.

     2.17 Swingline Loans. The Swingline Lender hereby agrees to extend to
Borrowers Swingline Loans in the aggregate amount not to exceed One Million and
No/100 Dollars ($1,000,000.00), on the following terms and conditions.

     2.17.1 Use of Proceeds of Swingline Loans. Borrowers may use the proceeds
of Swingline Loans for any purpose permitted for the proceeds of the Revolving
Credit Loan under Section 2.2 of this Agreement. To the extent proceeds of
Swingline Loans are used for working capital purposes, they shall be applied to
reduce the amount of the Revolving Credit Loan that may be used for working
capital purposes under Section 2.2 of this Agreement.

                                       29
<PAGE>   31

     2.17.2   Swingline Note. The Swingline Loans shall be evidenced by the
Swingline Note.

     2.17.3   Funding of Swingline Loans Advanced Pursuant to Borrowing Notices.

     2.17.3(a) Applicability. Except for Swingline Loans made pursuant to
Account Agreements as provided in Section 2.17.4 hereof, the funding of
Swingline Loans shall be subject to this Section 2.17.3.

     2.17.3(b) Borrowing Notices. As long as Borrowers meet the conditions for
funding stated in this Agreement, Response, on behalf of Borrowers, may submit
requests for Swingline Loans ("Swingline Borrowing Notices") to the Swingline
Lender. All requests shall be made in writing (or by telephone, subject to such
security procedures as the Swingline Lender may require from time to time,
provided that all telephonic notices shall be confirmed by written Swingline
Borrowing Notices within one (1) Business Day) and shall specify the proposed
date of the requested disbursement and the aggregate amount of such
disbursement. Each Swingline Borrowing Notice shall irrevocably obligate
Borrowers to accept the Swingline Loan requested thereby. Swingline Borrowing
Notices shall be in such form as the Swingline Lender may from time to time
require.

     2.17.3(c) Funding of Swingline Loans. The Swingline Lender shall fund
Swingline Loans on the Banking Day following the Banking Day of the Swingline
Lender's receipt of the Swingline Borrowing Notice. All funds shall be disbursed
directly into an account maintained by Borrower with the Swingline Lender.
Borrowers agree that if the Swingline Lender elects to fund any requested
Swingline Loan(s) sooner after requested than is required hereunder, the
Swingline Lender may nevertheless use the entire response period allowed
hereunder upon receipt of any subsequent request, at its sole option.

     2.17.4 Funding of Swingline Loans Advanced Pursuant to Cash Management
Accounts. Borrower may have in effect from time to time separate agreements with
the Swingline Lender or its affiliates ("Account Agreements") establishing cash
management procedures that may involve the automatic disbursement of Swingline
Loans. The Account Agreements may be established using standardized forms that
do not address the specific circumstances of the Swingline Loan. To resolve
potential inconsistencies between this Agreement and Account Agreements, the
terms of this Agreement and of Account Agreements shall relate to one another as
follows:

     2.17.4(a) Funding and Payment Procedures Controlled by Account Agreements.
The Account Agreements shall control this Agreement as to (i) Section 2.17.3
hereof regarding funding procedures, and (ii) Interest Payment Dates, to the
extent that an Account Agreement may provide for such payment more frequently
than otherwise required under this Agreement.

     2.17.4(b) Certain Provisions Controlled by this Agreement. Notwithstanding
any provision of an Account Agreement to the contrary, except as provided above
in Section 2.17.4(a) hereof, the provisions of this Agreement shall control any
Account Agreement to the extent that an Account Agreement may be inconsistent
with this Agreement.

     2.17.4(c) Continuing Warranty Under Account Agreements. Because Account
Agreements may provide for the making of Swingline Loans without formal draw
requests from Borrowers, Borrowers agree that Borrowers' warranty under Section
2.17.5 hereof as to the satisfaction of all conditions to the right to receive
Swingline Loans shall be a continuing one during any period that such an Account
Agreement may be in effect. Therefore, any Swingline Loans funded by the


                                       30
<PAGE>   32

Swingline Lender pursuant to an Account Agreement after the failure of a
condition stated in Article III hereof shall be deemed made upon the affirmative
misrepresentation of Borrowers unless the Swingline Lender has received written
notice of and waived the failed condition in writing.

     2.17.5 Implied Representations Upon Request for Swingline Loan. Upon making
any request for a Swingline Loan, Borrowers shall be deemed to have warranted to
the Swingline Lender that all conditions to funding are satisfied as of the
submission of the request to the Swingline Lender.

     2.17.6 Advance Not Waiver. The Swingline Lender's making of any Swingline
Loan that it is not obligated to make under any provision of Article III hereof
or any other provision hereof shall not be construed as a waiver of the
Swingline Lender's right to withhold future Swingline Loans, notify Agent of an
Event of Default, or otherwise demand strict compliance with this Agreement.

     2.17.7 Interest. Interest shall be charged and paid on each Swingline Loan
as follows:

     2.17.7(a) Rate of Interest. Interest shall accrue on Swingline Loans at an
annual rate equal to the Prime Rate, said rate to change contemporaneously with
any change in the Prime Rate.

     2.17.7(b) Calculation of Interest. Interest shall be computed on the basis
of a 360-day year counting the actual number of days elapsed.

     2.17.7(c) Payment of Interest. Interest shall be due and payable in arrears
without notice on each Interest Payment Date.

     2.17.7(d) Default Rate. Notwithstanding the foregoing, upon the occurrence
of an Event of Default and during the continuation of such Event of Default
until it is cured or waived, interest shall be charged at the Default Rate,
regardless of whether the Swingline Lender has elected to exercise any other
remedies available to it, including, without limitation, acceleration of the
maturity of the outstanding principal of the Swingline Loans. All such interest
shall be paid at the time of and as a condition precedent to the curing of any
such Event of Default to the extent any right to cure is given in this
Agreement.

     2.17.7(e) Usury Savings Provision. It is the intention of the parties that
all charges under or in connection with this Agreement and the Obligations,
however denominated, and including (without limitation) all interest, commitment
fees, late charges and loan charges, shall be limited to the Maximum Lawful
Amount. Such charges hereunder shall be characterized and all provisions of the
Credit Documents shall be construed as to uphold the validity of charges
provided for therein. If for any reason whatsoever, however, any charges paid or
contracted to be paid in respect of the Swingline Loans shall exceed the Maximum
Lawful Amount, then, ipso facto the obligation to pay such interest and/or other
charges shall be reduced to the Maximum Lawful Amount in effect from time to
time, and any amounts collected by Lender that exceed the Maximum Lawful Amount
shall be applied to the reduction of the principal balance of the Swingline
Loans and/or refunded to Borrowers so that at no time shall the interest or loan
charges paid or payable in respect of the Swingline Loans exceed the Maximum
Lawful Amount. This provision shall control every other provision herein and in
any and all other agreements and instruments now existing or hereafter arising
between Borrowers and the Swingline Lender with respect to the Swingline Loans.

                                       31
<PAGE>   33

     2.17.8 Repayment of Principal. All remaining principal, interest and
expenses outstanding under the Swingline Loans shall become due in full on the
Maturity Date or the earlier acceleration of the Revolving Credit Loan in
accordance with the terms of this Agreement. Borrowers may at any time prepay
any outstanding Swingline Loans in whole or in part without premium or penalty.

     2.17.9 Procedures Among Lenders Upon Event of Default. Upon the occurrence
of an Event of Default, Lenders shall acquire participation interests in the
outstanding Swingline Loans as necessary to cause each Lender to own a Pro Rata
interest in the outstanding Swingline Loans, pursuant to such documentation as
Agent may deem necessary. The obligation of each Lender to acquire such a
participation interest shall be unconditional and, without limiting the
foregoing, shall remain in effect irrespective of (i) the occurrence of any
Event of Default or Unmatured Default, (ii) the financial condition of
Borrowers, the Agent, the Swingline Lender or any other Lender or (iii) the
termination or cancellation of the Commitments (provided that such Swingline
Loan was made prior to the date of such termination or cancellation). The
Swingline Loans shall thereafter be administered by Lenders and Agent as though
the Swingline Loans were amounts outstanding under the Revolving Credit Loan.
Additionally, to this end, upon the occurrence and continuation of an Event of
Default, Agent may, in its discretion, and without Borrowers' consent, cause an
advance to be made under the Revolving Credit Loan sufficient to repay the
outstanding Swingline Loans, even if an Event of Default is then outstanding.

     2.18 Withholding Tax Exemption. Each Lender that is not incorporated or
organized under the laws of the United States of America, or a state thereof,
shall, on or before the date such Lender becomes a party to this Agreement,
deliver to each of Response and the Agent two duly completed copies of United
States Internal Revenue Service Form 1001 or 4224, certifying in either case
that such Lender is entitled to receive payments under this Agreement and such
Lender's Revolving Credit Note without deduction or withholding of any United
States federal income taxes. Each Lender that so delivers a Form 1001 or 4224
further undertakes to deliver to each of Response and the Agent two additional
copies of such form (or a successor form) on or before the date that such form
expires (currently, three successive calendar years for Form 1001 and one
calendar year for Form 4224), becomes obsolete or otherwise is required to be
resubmitted as a condition to obtaining an exemption from a required withholding
or deduction of United States federal income tax or after the occurrence of any
event requiring a change in the most recent forms so delivered by it, and such
amendments thereto or extensions or renewals thereof as may be reasonably
requested by Response or the Agent, in each case certifying that such Lender is
entitled to receive payments under this Agreement and such Lender's Revolving
Credit Note without deduction or withholding of any United States federal income
taxes, unless an event (including without limitation any change in treaty, law
or regulation) has occurred after the Closing Date and prior to the date on
which any such delivery would otherwise be required that renders all such forms
inapplicable or that would prevent such Lender from duly completing and
delivering any such form with respect to it and such Lender promptly advises
Response and the Agent that it is not capable of receiving payments without any
deduction or withholding of United States federal income tax.

                            III. CONDITIONS PRECEDENT

     3.1 Conditions to Initial Advance. Lenders shall not be obligated to make
their initial Loans pursuant to this Agreement unless and until Borrowers
satisfy the following conditions:

     3.1.1 Credit Documents. Borrowers shall have delivered to Lenders and to
Agent the following documents, fully executed and in form and substance
acceptable to Agent:



                                       32
<PAGE>   34

     3.1.1(a) Credit Agreement.  This Agreement.

     3.1.1(b) Notes. The Notes made by Borrowers payable to the order of the
respective Lenders in the maximum principal amounts of the Lenders' respective
Commitments and the Swingline Note.

     3.1.1(c) Security Agreements.  Security Agreements executed by Borrowers.

     3.1.1(d) Pledge of Equity Interests in Subsidiaries. Pledge Agreements,
Irrevocable Proxies and Blank Stock Powers, evidencing a first priority
perfected security interest in all of the ownership interests of Borrowers'
Subsidiaries listed on Schedule 3.1.1(d) and all dividends, distributions and
other property related thereto, together with all promissory notes (duly
endorsed in blank) and the original certificates evidencing the pledged stock,
partnership rights and interests in limited liability companies.

     3.1.1(e) Charters. Certified Copies of the Borrowers' corporate charters
and all amendments thereto, issued by the Secretaries of State for their states
of domicile.

     3.1.1(f) Bylaws.  Certified Copies of Bylaws for the Borrowers.

     3.1.1(g) Certificates of Good Standing. Certificates of good standing or
existence, as applicable, issued as to the Consolidated Entities by the
Secretaries of State for the states of their domicile.

     3.1.1(h) Foreign Qualification. Certificates of Qualification issued by the
Secretaries of State for each state in which a Consolidated Entity is required
to qualify as a foreign corporation.

     3.1.1(i) Resolutions. Certified Copies of Resolutions authorizing the
execution of all applicable Credit Documents on behalf of Borrowers.

     3.1.1(j) Opinions of Borrowers' Counsel. Opinions of counsel to the
Consolidated Entities addressed to Agent and Lenders, addressing matters
reasonably required by Lenders, Agent and their counsel.

     3.1.1(k) UCC Searches. UCC search reports on Borrowers from such
jurisdictions and filing offices as Lenders and Agent may require.

     3.1.1(l) Closing Statement and Funding of Expenses. Loan Closing Statement
describing expenses and fees due in connection with the closing of the Loans and
payment thereof in immediately available funds.

     3.1.1(m) Interest Rate Protection. Documents evidencing interest rate
protection acceptable to Lenders for at least 50% of the projected outstanding
principal balance of the Loans.

     3.1.1(n) Other Documents. Such other documents as Lenders or Agent may
reasonably require, including subordination agreements executed by the Borrowers
in favor of the Agent.

     3.1.1(o) Landlord Consents. Landlord consents from each landlord with
respect to the leased premises of the Borrowers listed on Schedule 3.1.1(o).

                                       33
<PAGE>   35

     3.1.1(p) Completion of Exhibits and Schedules. The completion of all
exhibits and schedules to this Agreement, which shall be satisfactory to Agent,
in its sole discretion.

     3.1.2 Additional Conditions. Borrowers shall have satisfied the following
additional conditions, to Lenders' and Agent's satisfaction:

     3.1.2(a) Warranties. All warranties made in the Credit Documents must be
true in all material respects and shall be true in all material respects taking
into account the funding of the requested Loan.

     3.1.2(b) Covenants. All covenants made in the Credit Documents must have
been complied with and shall have been complied with taking into account the
funding of the requested Loan.

     3.1.2(c) Absence of Unmatured Default. No Event of Default or Unmatured
Default shall exist under this Agreement.

     3.1.2(d) No Adverse Change. There must be no Material Adverse Change since
the date of the Financial Statements.

     3.1.2(e) Regulatory Diligence. The completion of healthcare regulatory
diligence to the satisfaction of Agent and its counsel.

     3.1.2(f) Ownership Structure. Lenders' satisfaction upon a review of
Response's present capital structure as set forth in Schedule 5.26 hereof.

     3.1.2(g) Projections. Lenders' receipt of financial projections prepared by
Borrowers covering Borrowers' anticipated operations for the next three (3)
years.

     3.2 Conditions to Subsequent Loans. Lenders shall not be obligated to make
any Loan unless all of the following conditions are satisfied as of the time of
the request and of funding:

     3.2.1 Conditions to Initial Advance. All of the conditions in Section 3.1
hereof must have been satisfied.

     3.2.2 Warranties. All warranties made in the Credit Documents must be true
in all material respects and shall be true in all material respects taking into
account the funding of the requested Loan.

     3.2.3 Covenants. All covenants made in the Credit Documents must have been
complied and shall have been complied with taking into account the funding of
the requested Loan.

     3.2.4 Absence of Unmatured Default. No Event of Default or Unmatured
Default shall exist under this Agreement.

     3.2.5 Material Adverse Change. There shall not have occurred a Material
Adverse Change.

     3.3 Participating Entity. The Agent shall also have received on or before
any date after the Closing Date on which a person becomes a Participating Entity
(i) a copy of resolutions of the Board of Directors and, if necessary, the
shareholders, partners or members of such person certified as in full force and
effect on the date thereof by the Secretary or Assistant Secretary of such
person, authorizing such person's execution, delivery and performance of, the
Credit


                                       34
<PAGE>   36

Documents and all other agreements and instruments that this Agreement requires
to be executed, delivered and performed by such person; (ii) a copy of the
organizational documents of such person, certified as true and correct on and as
of the date on which Credit Documents are executed and delivered by such person;
(iii) certificates of good standing with respect to such person from the
appropriate Governmental Authorities in the jurisdiction under the laws of which
such person is incorporated or formed; (iv) an opinion of counsel to such person
consistent with the form of the opinions of counsel to the Borrowers previously
delivered (with such changes therein as are appropriate in the circumstances) as
to the execution and delivery by such person of the Credit Documents and other
matters related thereto; (v) fully executed copies of all Credit Documents that
this Agreement requires to be executed or delivered (or both) by such person
(including a fully executed Assumption Agreement); and (vi) such additional
supporting documents as the Agent or its counsel may reasonably request.

     3.4 Conditions Subsequent.

     3.4.1 Agreement to Pledge. At such time as the prohibition to pledging the
interest of the limited liability companies owned by the Consolidated Entities
and further described on Schedule 3.4.1 is deleted, Borrowers shall promptly
cause the interest in such limited liability companies to be pledged to the
Agent to secure the Obligations.

     3.4.2 Lockboxes. Within 90 days after the Closing Date, Borrowers and their
Subsidiaries shall execute or, in the case of Providers, cause to be executed
Lockbox Agreements in form and substance acceptable to the Agent. The Borrowers
shall have an option to extend the time in which to obtain the Lockbox
Agreements for an additional 30 days upon their written request to the Agent for
such extension.

     3.4.3 Landlord Consents. Within 120 days after the Closing Date, Borrowers
shall have used their best efforts to obtain landlord consents and waivers from
those landlords of leased premises listed on Schedule 3.4.3.

     3.4.4 UCC-1 Financing Statements. Within 15 days after the Closing Date,
Response shall deliver to the Agent, fully executed UCC-1 Financing Statements
listing Response as Secured Party, the entities set forth on Schedule 3.4.4 as
debtors, and the Agent as assignee of Response to be filed in the appropriate
jurisdictions.


                       IV. REPRESENTATIONS AND WARRANTIES

Borrowers represent and warrant to Lenders and Agent that:

     4.1 Capacity. Each Consolidated Entity is a corporation or other entity as
set forth in Schedule 4.1 hereof, and is duly organized, validly existing and in
good standing under the laws of the state of its domicile as set forth in
Schedule 4.1. Each Consolidated Entity is qualified or authorized to do business
in all jurisdictions in which its ownership of property or conduct of business
requires such qualification or authorization or where the failure to be so
qualified or authorized would not have a Material Adverse Effect. Each
Consolidated Entity has the power and authority to own its Properties and to
carry on its business as now being conducted and as proposed to be conducted
after the execution hereof, to execute and deliver this Agreement and the other
Credit Documents, and to perform its obligations hereunder and under the other
Credit Documents.

                                       35
<PAGE>   37

     4.2 Authorization. The execution, delivery and performance of this
Agreement and the other Credit Documents by each Consolidated Entity executing
such documents has been duly authorized by all requisite action.

     4.3 Binding Obligations. This Agreement is and the other Credit Documents,
when executed and delivered to Lender, will be, legal, valid and binding upon
each Consolidated Entity who is a party thereto, enforceable in accordance with
its respective terms, subject only to principles of equity and laws applicable
to creditors generally, including bankruptcy laws.

     4.4 No Conflicting Law or Agreement. The execution, delivery and
performance of this Agreement and the other Credit Documents by each
Consolidated Entity does not constitute a breach of or default under, and will
not violate or conflict with, any provisions of the corporate charter or other
constituent documents of a Consolidated Entity; any contract, financing
agreement, lease, or other agreement to which a Consolidated Entity is a party
or by which its Properties may be affected, the violation of which could have a
Material Adverse Effect; or any Law to which a Consolidated Entity is subject or
by which its Properties may be affected, the violation of which could have a
Material Adverse Effect; nor will the same result in the creation or imposition
of any Encumbrance upon any Property of any Consolidated Entity, other than
those contemplated by the Credit Documents.

     4.5 No Consent Required. The execution, delivery, and performance of this
Agreement and the other Credit Documents by the Consolidated Entities do not
require the consent or approval of or the giving of notice to any Person except
for those consents which have been duly obtained and are in full force and
effect on the date hereof and others, if any, which by their omission could not
result in a Material Adverse Effect.

     4.6 Financial Statements. The Financial Statements are complete and
correct, have been prepared in accordance with GAAP, and present fairly the
financial condition and results of operations of the Consolidated Entities as of
the date and for the period stated therein, subject to year-end adjustments. No
Material Adverse Change has occurred since the date of the Financial Statements.
Borrowers acknowledge that Lenders have advanced (or shall advance) the Loans in
reliance upon the Financial Statements.

     4.7 Fiscal Year. Each Consolidated Entity's fiscal year ends on December 31
of each year.

     4.8 Litigation. Except as disclosed on Schedule 4.8 hereto, (i) there is no
litigation, arbitration, legal or administrative proceeding, tax audit,
investigation, or other action or proceeding of any nature pending against any
Consolidated Entity or any of its Properties, and (ii) there is no litigation,
arbitration, legal or administrative proceeding, tax audit, investigation, or
other action or proceeding of any nature threatened in writing against a
Consolidated Entity which, if adversely determined, could have a Material
Adverse Effect. No Consolidated Entity is subject to any outstanding court,
arbitral or administrative order, writ or injunction. To the Best of Borrowers'
Knowledge, no facts exist under which third parties have unasserted claims
against any Consolidated Entity which, if adversely determined, could have a
Material Adverse Effect.

     4.9 Taxes: Governmental Charges. Each Consolidated Entity has filed or
caused to be filed or has lawfully extended the deadline for filing all tax
returns and reports required to be filed. Each Consolidated Entity has paid, or
made adequate provision for the payment of, all Taxes that have or may have
become due pursuant to such returns or otherwise, or pursuant to any assessment
received by it, except such Taxes, if any, as are being contested in good faith
by appropriate proceedings and for which adequate reserves have been provided.
To the Best of

                                       36
<PAGE>   38

Borrowers' Knowledge, there is no proposed material tax assessment against any
Consolidated Entity. No extension of time for the assessment of federal, state
or local taxes of any Consolidated Entity is in effect or has been requested,
except as disclosed in Schedule 4.9 hereto. Each Consolidated Entity has timely
made all required remittances of withholding deposits and other assessments
against payroll expenditures.

     4.10 Title to Properties. Each Consolidated Entity has good and marketable
title to its Properties, free and clear of all Encumbrances except for Permitted
Encumbrances.

     4.11 No Default. No Consolidated Entity is in default in any respect that
affects its business, Properties, operations, or condition, financial or
otherwise, under any indenture, mortgage, deed of trust, obligation to equity
holders, credit agreement, note, agreement, lease, sale agreement or other
instrument to which any Consolidated Entity is a party or by which its
Properties are bound, which default could have a Material Adverse Effect. To the
Best of Borrowers' Knowledge, no other party to any contract with any
Consolidated Entity under which a default could have a Material Adverse Effect
is in default or breach thereof and no circumstances exist which, with the
giving of notice and/or the passing of time would constitute such default or
breach. No Event of Default or Unmatured Default exists under this Agreement.

     4.12 Casualties: Taking of Properties. Neither the business nor the
Property of any Consolidated Entity is presently impaired as a result of any
fire, explosion, earthquake, flood, drought, windstorm, accident, strike or
other labor disturbance, embargo, requisition or taking of property,
cancellation of contracts, permits, concessions by any domestic or foreign
government or any agency thereof, riot, activities of armed forces or acts of
God or of any public enemy, in any case as could have a Material Adverse Effect.

     4.13 Compliance with Laws. No Consolidated Entity is in violation of any
Law to which it, its business or any of its Properties are subject, the
violation of which would likely have a Material Adverse Effect, and, to the Best
of Borrowers' Knowledge, there are no outstanding citations, notices or orders
of noncompliance issued to any Consolidated Entity under any such Law, the
violation of which would likely have a Material Adverse Effect. Each
Consolidated Entity has obtained all licenses, permits, franchises, or other
governmental authorizations necessary to the ownership of its Properties or to
the conduct of its business, except for those which, if not obtained, could not
have a Material Adverse Effect. Each professional employee, officer and director
of a Consolidated Entity providing professional services is duly licensed
(where license is required) by each state or state agency or commission, or any
other governmental agency having jurisdiction over the provisions of such
services by such employee, officer or director, in which the Consolidated Entity
is located, required to enable such employee, officer or director to provide the
professional services necessary to enable the Consolidated Entity to operate as
currently operated and as presently contemplated to be operated except to the
extent the failure to have such a license would not have a Material Adverse
Effect. All such required material licenses are in full force and effect on the
date hereof and have not been revoked or suspended or otherwise limited.

     4.14 Compliance with Fraud and Abuse Laws. Without limiting any other
provision of this Agreement, (a) no Consolidated Entity and no Provider is in
violation of any Fraud and Abuse Law, the violation of which could have a
Material Adverse Effect and (b) neither the Borrowers nor any Subsidiary, nor
any of its stockholders, officers or directors have engaged on behalf of
Borrower or any Subsidiary in any of the following: (i) knowingly and willfully
making or causing to be made a false statement or representation of a material
fact in any applications for any benefit or payment under the Medicare or
Medicaid program; (ii) knowingly and willfully

                                       37
<PAGE>   39

making or causing to be made any false statement or representation of a material
fact for use in determining rights to any benefit or payment under the Medicare
or Medicaid program; (iii) failing to disclose knowledge by a claimant of the
occurrence of any event affecting the initial or continued right to any benefit
or payment under the Medicare or Medicaid program on its own behalf or on behalf
of another, with intent to secure such benefit or payment fraudulently; (iv)
knowingly and willfully soliciting or receiving any remuneration (including any
kickback, bribe or rebate), directly or indirectly, overtly or covertly, in cash
or in kind or offering to pay such remuneration (a) in return for referring an
individual to a Person for the furnishing or arranging for the furnishing of any
item or service for which payment may be made in whole or in part by Medicare or
Medicaid, or (b) in return for purchasing, leasing or ordering or arranging for
or recommending the purchasing, leasing or ordering of any good, facility,
service, or item for which payment may be made in whole or in part by Medicare
or Medicaid. With respect to this Section, knowledge by a senior officer of the
Borrowers or a Subsidiary of any of the events described in this Section shall
not be imputed to the Borrowers or such Subsidiary unless such knowledge was
obtained or learned by a senior officer in his or her official capacity as a
senior officer of the Borrowers or such Subsidiary. No activity of the Borrowers
or any Subsidiary shall be considered to be a breach of this Section, except in
the case of a knowing and willful violation thereof, until the Borrowers or such
Subsidiary has received notification, written or oral, by a Governmental
Authority of competent jurisdiction as to any such violation.

     4.15 ERISA. No ERISA Event has occurred with respect to any Plan or is
reasonably expected to occur with respect to any Plan.

     4.16 Full Disclosure of Material Facts. Borrowers have fully advised
Lenders of all matters involving the financial condition, business, operations
and Properties of the Consolidated Entities that would be reasonably expected to
have a Material Adverse Effect. No information, exhibit, or report furnished or
to be furnished by Borrowers to Lenders in connection with this Agreement
contains, as of the date thereof, any misrepresentation of fact or failed or
will fail to state any material fact, the omission of which would render the
statements therein materially false or misleading.

     4.17 Accuracy of Projections. With respect to all business plans and other
forecasts and projections furnished by or on behalf of Borrowers and made
available to Lenders relating to the financial condition, business, operations
or Properties of the Consolidated Entities, all facts stated as such therein
were true and complete in all material respects as of the time made and all
estimates and assumptions were made in good faith and believed to be reasonable
at the time made. As of the Closing Date, nothing has come to the attention of
Borrowers that has changed its assessment of any such matters, except for
changes that could not have a Material Adverse Effect.

     4.18 Investment Company Act. No Consolidated Entity is an "investment
company" under the Investment Company Act of 1940, as amended.

     4.19 Personal Holding Company. No Consolidated Entity is a "personal
holding company" as defined in Section 542 of the IRC.

     4.20 Solvency. Each Consolidated Entity is Solvent as of the date hereof
and will remain Solvent upon the consummation of the transactions contemplated
hereby.

                                       38
<PAGE>   40

     4.21 Chief Executive Office. The address designated herein to which notices
are to be sent under this Agreement is Borrowers' chief executive office within
the meaning of Tennessee Code Annotated Section 47-9-103(3)(d).

     4.22 Subsidiaries. Borrowers have no Subsidiaries, except for those listed
on Schedule 4.1 hereto, which schedule further describes the present ownership
of each Subsidiary.

     4.23 Ownership of Patents, Licenses, Etc. The Consolidated Entities own all
licenses, permits, franchises, registrations, patents, copyrights, trademarks,
trade names or service marks, or the rights to use the foregoing, that are
necessary for the continued operation of their business except for such
licenses, etc., which, if not held or owned, could not have a Material Adverse
Effect.

     4.24 Environmental Compliance. Each Consolidated Entity has duly complied
with, and their Properties are owned and operated in compliance with, all
Environmental Laws, the violation of which could have a Material Adverse Effect.
There have been no citations, notices or orders of non-compliance issued to any
Consolidated Entity or, to the Best of Borrowers' Knowledge, relating to their
business or Properties pursuant to any Environmental Law. Each Consolidated
Entity has obtained all required federal, state and local licenses, certificates
or permits relating to them and their Properties as required by applicable
Environmental Laws, except for those which, if not obtained, could not have a
Material Adverse Effect

     4.25 Labor Matters. No Consolidated Entity is subject to any collective
bargaining agreements or any decrees or orders requiring them to recognize, deal
with or employ any Person. No demand for collective bargaining has been asserted
against any Consolidated Entity by any union or organization. No Consolidated
Entity has experienced any strike, labor dispute, slowdown or work stoppage due
to labor dispute and, to the best knowledge of Borrowers, there is no such
strike, dispute, slowdown or work stoppage threatened against any Consolidated
Entity. All Consolidated Entities are in compliance in all material respects
with the Fair Labor Standards Act of 1938, as amended.

     4.26 OSHA Compliance. All Consolidated Entities are in compliance in all
material respects with the Federal Occupational Safety and Health Act, as
amended, and all regulations under the foregoing.

     4.27 Regulation U. No Consolidated Entity is engaged in the business of
extending credit for the purpose of purchasing or carrying margin stock (within
the meaning of Regulation U issued by the Board of Governors of the Federal
Reserve System). No proceeds of any Loan will be used to purchase or carry any
margin stock (within the meaning of Regulation U issued by the Board of
Governors of the Federal Reserve System) in violation of applicable law,
including, without limitation, Regulation U issued by the Board of Governors of
the Federal Reserve System.

     4.28 Affiliate Transactions. No Consolidated Entity is a party to any
transaction, contract or agreement with any Affiliate, except for Service
Agreements, lease agreements and other agreements among Borrowers and its
Subsidiaries and those other agreements described in Schedule 4.28 hereof.

     4.29 Year 2000 Compatibility. The Borrowers have developed a comprehensive
plan (the "Y2K Plan") for insuring that the Borrowers' and their Subsidiaries'
software and hardware systems (including all equipment) which impact or affect
in any way the business operations of the Borrowers and their Subsidiaries will
be Year 2000 Compliant and Ready. The Borrowers


                                       39
<PAGE>   41

and their Subsidiaries have met the Y2K Plan milestones such that all hardware
and software systems will be Year 2000 Compliant and Ready in accordance with
the Y2K Plan.


                            V. AFFIRMATIVE COVENANTS

     Borrowers covenant that, during the term of this Agreement (and thereafter
where expressly stated herein):

     5.1   Payment of Obligations. Borrowers shall pay all amounts owed under
the Obligations when due.

     5.2   Maintenance of Existence and Business. Except for transactions among
Consolidated Entities permitted under this Agreement, each Consolidated Entity
shall maintain its fundamental existence, name, rights, and franchises, and
shall maintain its qualification and good standing in all states in which such
qualification is necessary, and shall continue to operate in the same type of
business as such Consolidated Entity engages in as of the date hereof.

     5.3   Financial Statements and Reports. Borrowers shall furnish to Agent
the following, all of which must be in form and substance satisfactory to
Lenders (the financial reports below and all other reports required of Borrowers
under this Agreement shall be delivered in sufficient counterparts that each
Lender and Agent may have an original counterpart thereof):

     5.3.1 Monthly Financial Reports. As soon as available, and in any event by
the thirtieth (30th) day following the end of a month, Response shall deliver to
Agent and Lenders a balance sheet and income statement of Response for and as of
the end of the preceding month, all prepared by Response on a consolidated basis
and certified by Response's president or chief financial officer to be complete
and correct in all material respects and to present fairly, in accordance with
GAAP (excluding year-end adjustments and required footnote disclosures), the
consolidated financial condition of Response as of the date of such statements.

     5.3.2 Quarterly Financial Reports. As soon as available, and in any event
by the forty-fifth (45th) day of each fiscal quarter, Response shall prepare and
deliver to Agent and Lenders a consolidated balance sheet, income statement and
statement of cash flows of Response for and as of the end of the preceding
fiscal quarter, certified by Response's President or Chief Financial Officer to
be complete and correct and to present fairly, in accordance with GAAP
(excluding year-end adjustments and required footnote disclosures), the
consolidated financial condition of Response as of the date of such statements
and the consolidated results of its operations and its cash flow for such
period. Supplemental to such basic financial statements, Response shall deliver
to Agent calculations of all financial ratios; the certification of Response's
President or Chief Financial Officer as to the absence of any Event of Default
or Unmatured Default; and by-Practice financial summaries addressing Practice
revenues, expenses and fees to Consolidated Entities in form and substance
acceptable to Agent.

     5.3.3 Annual Financial Reports. As soon as available, and in any event
within ninety (90) days after the end of each fiscal year, Borrower shall
deliver to Agent and Lenders the audited consolidated balance sheet of Response
as of the end of such year and the related audited consolidated statements of
income, retained earnings and cash flows for such year, together with supporting
schedules, all such statements prepared in accordance with GAAP and accompanied
by an unqualified audit report prepared by an independent "big five" certified
public accountant acceptable to Agent showing the consolidated financial
condition of Response at the close of such

                                       40
<PAGE>   42

year and the consolidated results of its operations, changes in its retained
earnings and its cash flows for such year. Supplemental to the audited year-end
financial statements, Response shall deliver to Agent calculations of all
financial ratios as determined based upon the audited financial statements and
the certification of Borrower's President or Chief Financial Officer as to the
absence of any Event of Default or Unmatured Default.

     5.3.4 Owner Mailings. Promptly upon the sending thereof, Response shall
deliver to Agent and Lenders a copy of each statement, report or notice sent to
its shareholders and simultaneously with the distribution to each member of
Response's Board of Directors, Response shall deliver to the Agent and Lenders a
copy of Response's quarterly board package that is presented to each member of
Response's Board of Directors.

     5.3.5 Accountant Reports. Promptly upon the receipt thereof Response shall
deliver to Agent and Lenders a copy of each other report (other than work
papers) submitted to Response or any Subsidiary by its accountants in connection
with any annual, interim or special audit made by them including, but not
limited to, all management letters issued to Response.

     5.3.6 Acquisition Certification. Response shall submit to Agent an
Acquisition Compliance Certificate in the form attached hereto as Exhibit 1.2
within the time periods set forth therein.

     5.3.7 Other Information. Response shall provide Agent with such additional
information regarding the financial condition, properties, operations and
prospects of the Consolidated Entities and their consolidated entities as Agent
may reasonably require.

     5.4   Additional Information. Response shall provide such other information
respecting the condition or operations, financial or otherwise, of the
Consolidated Entities as Agent may from time to time reasonably request.

     5.5   Certain Additional Reporting Requirements.

     5.5.1 SEC Filings. Promptly upon the filing thereof, should such filings
become applicable, Response shall deliver to Agent copies of all regular,
periodic and special reports that any Consolidated Entity files with the United
States Securities and Exchange Commission or any successor thereto, or any
national securities exchanges or the National Association of Securities Dealers.

     5.5.2 Change in Accounting Policies. Response shall promptly notify Agent
in writing upon any material change in accounting policies or financial
reporting practices on the part of any Consolidated Entity.

     5.5.3 Notice to Agent Upon Perceived Breach. Response agrees to give Agent
prompt written notice of any action or inaction by or on behalf of Agent or
Lenders in connection with this Agreement or the Obligations that Borrowers
believe may be actionable against Lenders or Agent or a defense to payment of
any or all Obligations for any reason, including, but not limited to, commission
of a tort or violation of any contractual duty or duty implied by law provided,
however, that Response's failure to give such notice, if such failure is
unintentional and does not arise from Borrowers' gross negligence, shall not
foreclosure any such action or defense to be asserted by Borrowers.

     5.5.4 Changes in Constituent Documents. Borrowers shall promptly notify
Agent in writing of any change in the corporate charter or bylaws of Borrowers
or the fundamental documents of


                                       41
<PAGE>   43

any Subsidiary following the encumbrance of the stock thereof in favor of Agent
to secure Lenders as required under this Agreement, and shall provide Agent with
a copy of such change (Consolidated Entities are restricted in the adoption of
such amendments as provided elsewhere in the Credit Documents, and nothing
contained in this Section shall be deemed a waiver of such restrictions).

     5.5.5 Notice of Litigation. Response shall give Agent prompt written notice
of any litigation, arbitration, tax audit, administrative proceeding or
investigation that may hereafter be instituted or threatened in writing in which
Borrowers would be a party or which otherwise may affect any Consolidated Entity
or any of their business, operations or Properties, except for (i) actions
seeking only monetary damages in an amount of less than the amount equal to
one-half percent (1/2%) of Response's Consolidated EBITDA for the most recent
four (4) fiscal quarters for which Borrower has submitted financial statements
to Agent, as of the time of determination, and (ii) actions seeking only
monetary damages for personal injury or wrongful death and which are fully
covered by insurance, subject only to any applicable deductible.

     5.5.6 Other Notices. Response shall promptly notify Agent in writing if
Borrowers learn of the occurrence of (i) any event that constitutes an Event of
Default or an Unmatured Default, together with a detailed statement of the steps
being taken as a result thereof, or (ii) any Material Adverse Change.

     5.6   Taxes and Other Encumbrances. Each Consolidated Entity shall make due
and timely payment or deposit of all federal, state and local taxes, assessments
or contributions required of it by law, and execute and deliver to Agent, on
demand, appropriate certificates attesting to the payment or deposit thereof;
provided, however, that the Consolidated Entities shall not be required to pay
or discharge any such tax, assessment, charge or claim for as long as it is
being diligently contested in good faith by proper proceedings and for which
appropriate reserves are being maintained.

     5.7   Payment of Liabilities. Each Consolidated Entity shall pay all of its
Liabilities as and when the same becomes due in accordance with its terms.

     5.8   Compliance with Laws. Each Consolidated Entity shall observe and
comply with all Laws (including, but not limited to, Fraud and Abuse Laws), and
shall maintain all certificates, franchises, permits, licenses, and
authorizations necessary to the conduct of its business or the operation of its
Properties, except for such Laws, certificates, etc., which, if violated or not
obtained and full penalties were imposed for such violation, could not cause a
Material Adverse Effect. Each Consolidated Entity shall further use its best
efforts to assure the compliance by all Providers with all applicable Laws,
including, but not limited to, medical licensure and Fraud and Abuse Laws,
relating to their providing of professional services, except for those which, if
violated and full penalties were imposed for such violation, could not cause a
Material Adverse Effect.

     5.9   Maintenance of Property. All Consolidated Entities shall maintain
their Property (and any Property leased by or consigned or held under title
retention or conditional sales contracts) in good and workable condition at all
times, subject to ordinary wear and tear, normal discards and replacements due
to functional and useful-life obsolescence, and shall make all repairs,
replacements, additions, and improvements to their Property reasonably necessary
and proper to ensure that the business carried on in connection with their
Property may be conducted properly and efficiently at all times.

                                       42
<PAGE>   44

     5.10 Compliance with Contractual Obligations. Each Consolidated Entity will
perform all of its obligations in respect of all material contracts to which it
is a party and will use its best efforts to keep, and to take all action to
keep, such contracts in full force and effect and not allow any such contract to
lapse or be terminated or any rights to renew such to be forfeited or canceled,
if such lapse, etc. could have a Material Adverse Effect; provided, however,
that any such contract may lapse or be terminated or such renewal rights may be
forfeited or canceled if in the reasonable business judgment of the Consolidated
Entities it is in their best interests to allow or cause such lapse,
termination, forfeiture or cancellation.

     5.11 Further Assurances. The Consolidated Entities shall promptly cure any
defects in the creation, issuance, or delivery of the Credit Documents. The
Consolidated Entities at their expense will execute (or cause to be executed)
and deliver to Agent upon request all such other and further documents,
agreements, and instruments in compliance with or accomplishment of the
covenants and agreements applicable to them in the Credit Documents, or to
evidence further and to describe more fully any Collateral intended as security
for the Obligations, or to correct any omissions in the Credit Documents, or to
state more fully the Obligations and agreements set out in any of the Credit
Documents, or to perfect, protect, or preserve any Encumbrances created pursuant
to any of the Credit Documents, or to make any recordings, to file any notices,
or to obtain any consents, all as may be reasonably necessary or appropriate in
connection therewith. Borrowers appoint Agent as Borrowers' attorney-in-fact to
execute any financing statements or other instruments of perfection with respect
to the Collateral.

     5.12 Security Interest: Setoff. In order to further secure the payment of
the Obligations, Borrowers hereby grant to Agent and to each Lender a security
interest and right of setoff against all of Borrowers' presently owned or
hereafter acquired monies, items, credits, deposits and instruments (including
certificates of deposit) presently or hereafter in the possession of any Lender
or Agent. By maintaining any such accounts or other property with a Lender or
Agent, Borrowers acknowledge that Borrowers voluntarily subject the property to
the security interest arising hereunder. Subject to the provisions in Article IX
hereof, a Lender may exercise its rights under this Section without prior notice
(but with prompt notice following the setoff) following an Event of Default.
Borrowers agree that neither Lenders nor Agent shall be liable for the dishonor
of any instrument after notice of setoff shall have been duly given resulting
from a Lender's exercise of its rights under this Section.

     5.13 Insurance.

     5.13.1 General Insurance Requirements. In addition to the other specific
requirements set forth in this Agreement and in other Credit Documents, the
Consolidated Entities shall maintain insurance on all insurable Properties now
or hereafter owned by them against such risks and to the extent customary in
their industry, and shall maintain or cause to be maintained public liability
and worker's compensation insurance to the extent customary in the industry.

     5.13.2 Practice-Related Insurance Requirements. The Consolidated Entities
shall maintain insurance for claims, however characterized, against them in
connection with the provision of medical services by Providers and/or ancillary
services provided by them at Practices covered by Service Agreements, in an
amount of at least Five Hundred Thousand and No/100 Dollars ($500,000.00) per
occurrence and One Million and No/100 Dollars ($1,000,000.00) in the aggregate
for Providers who are physicians, which insurance shall name Lenders (or Agent
on behalf of Lenders) as additional insureds. The Consolidated Entities shall
further cause each Provider to maintain medical malpractice insurance of at
least Five Hundred Thousand and


                                       43
<PAGE>   45

No/100 Dollars ($500,000.00) per occurrence and One Million and No/100 Dollars
($1,000,000.00) in the aggregate.

     5.14 Accounts and Records. The Consolidated Entities shall maintain current
books of record and account, in which full, true, and correct entries will be
made of all transactions.

     5.15 Official Records. The Consolidated Entities shall maintain current
corporate and official records, minute books and stock ledgers and other records
appropriate to their form of organization.

     5.16 Banking Relationships. The Consolidated Entities shall maintain their
deposit accounts with Lenders or with other FDIC-insured depository
institutions.

     5.17 Right of Inspection. The Consolidated Entities shall permit any
officer, employee, or agent of a Lender or Agent to visit and inspect during
ordinary business hours any of their Property, to examine their books of record
and accounts and corporate records, to take copies and extracts from such books
of record and accounts, and to discuss the affairs, finances, and accounts of
the Consolidated Entities with their respective officers, accountants, and
auditors, all at such reasonable times and as often as a Lender may reasonably
desire and upon reasonable advance notice absent an Event of Default. Without
limiting Agent's right to obtain equitable relief as to any other appropriate
right in this Agreement or in other Credit Documents, Borrowers agree that the
rights in this Section may be enforced by affirmative injunction and, to the
extent the right to review records may be denied, the right may be enforced by a
restraining order prohibiting the interference by Borrowers with the exercise of
rights to review of the records pursuant to this Section. Absent an Event of
Default or Unmatured Default, all expenses of such inspections, etc. shall be
paid by Lenders, and in the presence thereof, all expenses shall be paid by
Borrowers.

     5.18 ERISA Information and Compliance. The Consolidated Entities shall
comply with ERISA and all other applicable laws governing any pension or profit
sharing plan or arrangement to which they are a party. The Consolidated Entities
shall (i) upon request, provide Agent with copies of any annual report required
to be filed pursuant to ERISA with respect to any Plan or any other employee
benefit plan; (ii) notify Agent upon the occurrence of any ERISA Event or of any
additional act or condition arising in connection with any Plan which they
believe might constitute grounds for termination thereof by the PBGC or for the
appointment of a trustee to administer the Plan; and (iii) furnish to Agent,
promptly upon request, such additional information concerning any Plan or any
other employee benefit plan as Agent may request.

     5.19 Indemnity: Expenses. Borrowers agree to indemnify, defend (with
counsel reasonably satisfactory to the indemnified party or parties) and hold
harmless Lenders and Agent against any loss, liability, claim or expense,
including reasonable attorneys' fees, that they may incur in connection with the
Credit Documents or the Obligations, except those losses, etc. that may result
from a Lender's or Agent's gross negligence or willful misconduct. Without
limiting the foregoing, upon demand by Agent, Borrowers will reimburse Lenders
and/or Agent for the following reasonable expenses if not paid by Borrowers
promptly after written demand by Agent:

     5.19.1 Taxes. All taxes that Lenders or Agent may be required to pay
because of the Obligations or because of Lenders' or Agent's interest in any
property securing the payment of the Obligations, excepting taxes based upon the
net income of Lender or Agent.

     5.19.2 Administration. All costs of the preparation of this Agreement and
any other related documents and the administration of the Obligations (except
for Lenders' and Agent's


                                       44



<PAGE>   46

usual overhead incurred in the acceptance and processing of payments, the
routine review of financial statements, certifications and reports, routine
communications with Borrower, and other ordinary activities that are not
occasioned by an Unmatured Default, Event of Default or by a request of Borrower
to waive or vary the terms of this Agreement).

     5.19.3 Protection of Collateral. All costs of preserving, insuring,
preparing for sale (whether by improvement, repair or otherwise) or selling any
Collateral.

     5.19.4 Costs of Collection. All court costs and other costs of collecting
any debt, overdraft or other obligation included in the Obligations.

     5.19.5 Litigation. All reasonable costs arising from any litigation,
investigation, or administrative proceeding (whether or not Agent or a Lender is
a party thereto) that Agent or a Lender may incur as a result of the Obligations
or as a result of their association with any of the Consolidated Entities,
including, but not limited to, expenses incurred by Agent or a Lender in
connection with a case or proceeding involving any Consolidated Entity under any
chapter of the Bankruptcy Code or any successor statute thereto.

     5.19.6 Attorneys' Fees. Reasonable attorneys' fees incurred in connection
with any of the foregoing.

If a Lender or Agent pays any of the foregoing expenses, they shall become a
part of the Obligations and shall bear interest at the Maximum Lawful Amount.
This Section shall remain in full effect regardless of the full payment of the
Obligations, the purported termination of this Agreement, the delivery of the
executed original of this Agreement to Borrowers, or the content or accuracy of
any representation made by Borrowers to Lenders or Agent; provided, however,
Agent may terminate this Section by executing and delivering to Borrowers a
written instrument of termination specifically referring to this Section.

     5.20 Assistance in Litigation. Borrowers covenant to, upon request,
cooperatively participate in any proceeding in which Borrowers are not an
adverse parry to Lenders or Agent and which concerns Lenders' or Agent's rights
regarding the Obligations or any Collateral.

     5.21 Name Changes. Borrowers shall give Agent at least thirty (30) days
prior written notice before any Consolidated Entity changes its name or begins
doing business under any trade name.

     5.22 Estoppel Letters. Borrowers covenant to provide Agent, within ten (10)
days after request, an estoppel letter stating (i) the balance of the
Obligations, (ii) whether Borrowers have any defenses to payment of the
Obligations, and (iii) the nature of any defenses to payment of the Obligations.
Such balance as presented for confirmation and the nonexistence of defenses
shall be presumed if Borrowers fail to respond to such a request within the
required period.

     5.23     Environmental Matters.

     5.23.1 Compliance With Environmental Laws. All Consolidated Entities will
(i) employ in connection with their operations, appropriate technology and
compliance procedures to maintain compliance with any applicable Environmental
Laws, the violation of which would reasonably be expected to have a Material
Adverse Effect, (ii) obtain and maintain any and all materials permits or other
permits required by applicable Environmental Laws in connection with its
operations, excepting only such permits, etc. which could not by their absence
cause a Material Adverse


                                       45
<PAGE>   47
Effect, and (iii) dispose of any and all Hazardous Substances only at
facilities and with carriers reasonably believed to possess valid permits
under any applicable state and local Environmental Laws. All Consolidated
Entities shall use their best efforts to obtain all certificates required by
law to be obtained by them from all contractors employed by them in connection
with the transport or disposal of any Hazardous Substances.

     5.23.2 Remedial Work. If any investigation, site monitoring, containment,
clean-up, removal, restoration or other remedial work of any kind or nature with
respect to any Consolidated Entity's Properties is required to be performed by
them under any applicable local, state or federal law or regulation, any
judicial order, or by any governmental or non-governmental entity or Person
because of, or in connection with, the current or future presence, suspected
presence, release or suspected release of a Hazardous Substance m or into the
air, soil, groundwater, surface water or soil vapor at, on, about, under, or
within any of a Consolidated Entity's Property (or any portion thereof),
Borrowers shall within 30 days after written demand for performance thereof (or
such shorter period of time as may be required under applicable law, regulation,
order or agreement), commence and thereafter diligently prosecute to completion,
all such remedial work.

     5.23.3 Indemnification of Lenders and Agent. Borrowers agree to indemnify,
defend (with counsel reasonably satisfactory to the indemnified party or
parties) and hold harmless Lenders and Agent against any loss, liability claim
or expense, including attorneys' fees, that Lender or Agent may incur as a
result of the violation or alleged violation of any Environmental Law by a
Consolidated Entity or with respect to any other violation of Environmental Laws
with respect to any Consolidated Entity's Properties. This covenant shall
survive the repayment of the Revolving Credit Loan.

     5.24 Opinions of Counsel. Borrowers agree that Agent may from time to time,
but not more frequently than once per calendar year absent an Unmatured Default
or an Event of Default, request in writing the opinion of in-house counsel
and/or outside healthcare counsel to the Consolidated Entities as to the
absence, except as disclosed in the opinion, of such counsel's knowledge of any
actual, threatened or asserted violation of any Fraud and Abuse Law on the part
of any Consolidated Entity and/or the Providers, and the sufficiency of
documentation then in use for the acquisition of Practices as complying with
Fraud and Abuse Laws. Absent the existence of an Unmatured Default or and Event
of Default, such opinions shall require no special diligence on the part of the
opining attorney(s), but only requiring a report of matters then known to such
attorneys, unless Agent specifically inquires about facts that Agent reasonably
believes may raise a Fraud and Abuse Law issue. Such opinions shall be in form
and substance acceptable to Agent, shall be delivered to Agent at Borrowers'
expense within fifteen (15) days of the date of request and shall address
specifically any facts inquired of in Agent's request.

     5.25 Creation or Acquisition of Subsidiaries. The Borrowers will cause each
Consolidated Entity that is hereafter acquired or created, promptly (but in no
event more than 30 days) after such Consolidated Entity is acquired or created,
to become a Participating Entity by execution of an Assumption Agreement,
appropriate Security Documents (as determined by the Lenders) and all other
documents necessary to cause it to become jointly and severally liable for the
Obligations (subject to the limitations provided in the Assumption Agreement);
and to cause the Obligations to be secured by a perfected first priority
security interest in and Lien on all of its real and personal property, then
owned or thereafter acquired.

                                       46
<PAGE>   48

     5.26 Existing Capital Structure of Borrower. Schedule 5.26 hereto includes
a description of Response's current ownership structure, including outstanding
stock and any warrants, convertible debt or other like instruments, and a list
of all Subordinated Debt now outstanding.

     5.27 Year 2000 Compatibility. The Borrowers will meet the milestones
contained in the Y2K Plan and will have all hardware (including all equipment)
and software systems Year 2000 Compliant and Ready (including all internal and
external testing) on or before October 1, 1999.

                             VI. NEGATIVE COVENANTS

     Borrowers covenant and agree that without the advance written consent of
Agent, until the Obligations are repaid in full:

     6.1 Debts, Guaranties, and Other Obligations. No Consolidated Entity shall
incur, create, assume, or in any manner become or be liable with respect to any
Liability, except the following:

     6.1.1 Obligations to Lenders. Any Obligations to Lenders under this
Agreement.

     6.1.2 Existing Liabilities. Liabilities, direct or contingent, of
Consolidated Entities existing on the date of this Agreement that are reflected
in Schedule 6.1.2 hereof.

     6.1.3 Endorsements. Endorsements of negotiable or similar instruments for
collection or deposit in the ordinary course of business.

     6.1.4 Trade Liabilities. Trade payables and accruals from time to time
incurred in the ordinary course of business.

     6.1.5 Taxes. Taxes, assessments, or other governmental charges that are not
delinquent or are being contested in good faith by appropriate action promptly
initiated and diligently conducted, if Borrowers have made the reserve therefor
required by GAAP.

     6.1.6 Seller Debt. Seller Debt, which must be unsecured, on terms
acceptable to Agent, and existing Subordinated Debt described on Schedule 6.1.6;
provided, however, no additional Subordinated Debt may be incurred without the
prior written consent of the Agent and Lenders.

     6.1.7 Purchase Money Debt. Purchase Money Debt, including Assumed Debt, not
to exceed (i) Five Million and No/100 Dollars ($5,000,000.00) in the aggregate,
including all Purchase Money Debt of all Consolidated Entities, (ii) Two Million
and No/100 Dollars ($2,000,000.00) in the aggregate, excluding for this Section
(ii) all Purchase Money Debt owed by individual Practices that have total
Purchase Money Debt of less than One Hundred Thousand and No/100 Dollars
($100,000.00) per Practice, or (iii) One Million and No/100 Dollars
($1,000,000.00) as to any single Practice, absent the prior written approval of
Agent as to this Section (iii).

     6.1.8 Accounting Accruals. Liabilities arising from reserves and accruals
required by GAAP that do not reflect liquidated and mature obligations to third
parties, including, but not limited to, current deferred income taxes.

     6.1.9 Liabilities Among Consolidated Entities. Liabilities incurred to
other Consolidated Entities incurred in the ordinary course of business.

                                       47
<PAGE>   49

     6.2 Change of Management. Response shall not allow or suffer any change of
management effecting a material change in the duties or change in the personnel
presently staffing the positions of Chairman, Chief Executive Officer or
President, as set forth in Schedule 6.2 hereto. Notwithstanding the foregoing,
should any of the named managers cease such active participation in Response's
management due to their death or disability, Agent shall allow Response a period
of sixty (60) days thereafter in which a management succession plan may be
presented to Agent so that Agent may, in its discretion, elect to accept new
management in lieu of prior management, subject to such revisions of this
Agreement as Agent may require.

     6.3 Change of Ownership. Response shall not cause or suffer to exist a
change of ownership or suffer the issuance of new stock or other event that
would result in the ownership of more than 25% of the stock of Response by any
Person not presently a shareholder thereof.

     6.4 Distributions. No Consolidated Entity shall declare or pay any dividend
or other distribution or redeem any of its capital stock except for dividend
payments and other distributions from Subsidiaries to Response.

     6.5 Encumbrances. No Consolidated Entity shall create, incur, assume, or
permit to exist any Encumbrance on any of its Property (now owned or hereafter
acquired) except for Permitted Encumbrances, and shall not undertake a
commitment of any kind in favor of any Person (other than Lenders) (i) requiring
that any or all of such Consolidated Entity's Property be or remain
unencumbered, or (ii) requiring that a Consolidated Entity grant an Encumbrance
(other than a Permitted Encumbrance) in favor of any Person (other than Lenders)
on a Consolidated Entity's Property under any circumstances whatsoever. No
Consolidated Entity shall sign or file under the Uniform Commercial Code a
financing statement that names such Consolidated Entity as debtor or the
equivalent or sign any security agreement authorizing any secured party
thereunder to file any such financing statement, except to secure Permitted
Encumbrances.

     6.6 Investments. No Consolidated Entity shall make investments (including
but not limited to acquisitions or purchases of the obligations or stock of, or
any other or additional interest) in any person, firm, partnership, joint
venture or corporation except: (a) those investments in existence as of the
Closing Date, (b) general obligations of, or obligations unconditionally
guaranteed as to principal and interest by, the United States of America
maturing within fifteen (15) months of the date of purchase, (c) commercial
paper having a rating of not less than "A2" or "P2" from Moody's or S & P,
respectively, (d) Permitted Acquisitions, (f) certificates of deposit and
bankers acceptances issued by a Lender or another banking institution with a
minimum net worth of Five Billion and No/100 Dollars ($5,000,000,000.00) and
having a letter of credit rating of not less than "A" from Moody's or S & P,
respectively, and (g) such other investments as Agent may approve, in its
discretion.

     6.7 Sales and Leasebacks. No Consolidated Entity shall enter into any
arrangement, directly or indirectly, with any Person other than another
Consolidated Entity by which such Consolidated Entity shall sell or transfer any
of its Property, whether now owned or hereafter acquired, and by which a
Consolidated Entity shall then or thereafter rent or lease as lessee such
Property or any part thereof or other Property that it intends to use for
substantially the same purpose or purposes as the Property sold or transferred.

     6.8 Change of Control. Response shall not suffer or permit the occurrence
of a Change of Control.

                                       48
<PAGE>   50

     6.9  Nature of Business. No Consolidated Entity shall suffer or permit any
material changes to be made in the character of its business as carried on at
the Closing Date, except for the accomplishment of Permitted Acquisitions.

     6.10 Further Acquisitions, Mergers, Etc. Except for Permitted Acquisitions
and transactions involving only Consolidated Entities, no Consolidated Entity
shall enter into any agreement to merge, consolidate, or otherwise reorganize or
recapitalize, or sell, assign, lease, or otherwise dispose of (whether in one
transaction or in a series of transactions) all or substantially all of their
Property (whether now owned or hereafter acquired).

     6.11 Advances. No Consolidated Entity shall extend any loans to any other
Persons, except for (i) loans to other Consolidated Entities in the ordinary
course of business and (ii) Provider Loans not to exceed Five Hundred Thousand
and No/100 Dollars ($500,000.00) per Practice and One Million and No/100 Dollars
($1,000,000.00) in the aggregate at any one time.

     6.12 Disposition of Assets. No Consolidated Entity shall dispose of any of
its assets other than in the ordinary course of their present business upon
terms standard in its industry.

     6.13 Inconsistent Agreements. No Consolidated Entity shall enter into any
agreement containing any provision which would be violated or breached by the
performance by Borrowers of the Obligations.

     6.14 Fictitious Names. Borrowers shall not use any name other than the name
used in executing this Agreement or any assumed or fictitious name.

     6.15 Subsidiaries and Affiliates. No Consolidated Entity shall create or
acquire any direct or indirect Subsidiary or Affiliate or divest itself of any
material assets by transferring them to any existing Subsidiary or Affiliate
other than Participating Entities; nor shall Borrowers enter into any
partnership, joint venture, or similar arrangement, or otherwise make any
material change in its corporate structure, except that Borrowers may acquire
and create Participating Entities from time to time in the ordinary course of
business.

     6.16 Place of Business. Borrowers shall not transfer its executive offices,
or maintain records with respect to accounts at any locations other than at the
address for notices specified herein and at the locations of Practices
affiliated with Borrowers, except as Agent may approve in its reasonable
discretion.

     6.17 Adverse Action With Respect to Plans. No Consolidated Entity shall
take any action to terminate any Plan which could reasonably result in a
material liability of a Consolidated Entity to any Person.

     6.18 Transactions With Affiliates. No Consolidated Entity shall enter into
any transaction with any Affiliate except in the ordinary course of business and
on fair and reasonable terms no less favorable to the Consolidated Entity than
it would obtain in a comparable arms length transaction with a Person not an
Affiliate.

     6.19 Constituent Document Amendments. No Consolidated Entity shall amend
its corporate charter or bylaws, except as necessary to accomplish corporate
transactions that do not require Lenders' or Agent's specific approval or
transactions for which such approval is necessary and has been granted.

                                       49
<PAGE>   51

     6.20 Adverse Transactions. No Consolidated Entity shall enter into any
transaction that materially and adversely affects or, to the best of its
knowledge, is likely to materially and adversely affect the Collateral or
Borrowers' ability to repay the Obligations.

     6.21 Margin Securities. No Consolidated Entity shall own, purchase or
acquire (or enter into any contract to purchase or acquire) any "margin
security" as defined by any regulation of the Federal Reserve Board as now in
effect or as the same may hereafter be in effect.

     6.22 Accounting Changes. Borrowers shall not change its fiscal year or make
any other significant change in consolidated or consolidating accounting
treatment and reporting practices, except as required or permitted by GAAP or
the Securities and Exchange Commission. Any change in fiscal year shall be
subject to Agent's prior written approval.

     6.23 Action Outside Ordinary Course. No Consolidated Entity shall take any
other action outside the ordinary course of their business.

     6.24 Modification of Subordinated Debt Documents. Response will not cause
or permit the Subordinated Debt to be modified, directly or indirectly, in any
manner that (a) would accelerate the stated maturity of any principal or
interest due thereunder or (b) might terminate or impair the subordination of
the Subordinated Debt to the Obligations.


                            VII. FINANCIAL COVENANTS

     7.1 Total Funded Debt to Capital. Borrowers shall maintain a ratio of Total
Funded Debt divided by Consolidated Capital of no greater than .50:1.00, tested
as of the end of each fiscal quarter.

     7.2 Total Funded Debt to Consolidated EBITDA. Borrowers shall maintain a
ratio of Total Funded Debt divided by Consolidated EBITDA, measured as of the
end of each fiscal quarter for the previous four consecutive fiscal quarters, of
no greater than 3.25:1.00 through the fiscal quarter ending December 31, 1999
and of no greater than 3.00:1.00 thereafter.

     7.3 Fixed Charge Coverage. Borrowers shall maintain a Fixed Charge Coverage
Ratio of at least 1.00:1.00 for the previous fiscal quarter, tested as of the
end of such fiscal quarter.

     7.4 Net Worth. Borrowers shall maintain a Consolidated Net Worth as of the
end of each fiscal quarter in an amount at least equal to the sum of Fifty
Million Five Hundred Sixty-Seven Thousand and No/100 ($50,567,000), (i) plus any
Net Proceeds of equity issuances and asset sales arising after the Closing Date,
and (ii) plus seventy-five percent (75%) of the amount of net income for the
fiscal quarter ending June 30, 1999 and for each fiscal quarter thereafter,
without adjustment for net losses.

     7.5 Capital Expenditures. Borrowers shall not permit Capital Expenditures
for any fiscal year, beginning with the fiscal year ending December 31, 1998, to
exceed three percent (3%) of Consolidated Net Revenues for the same fiscal year.

     7.6 Outstanding Accounts. As determined quarterly, accounts receivable,
calculated as an aggregate based upon the previous 90 days average revenues,
arising out of transactions with (a) physicians affiliated with a Practice shall
not be more than one hundred (100) days outstanding and (b) IMPACT Centers shall
not be more than one hundred twenty-five (125) days outstanding.

                                       50
<PAGE>   52


                             VIII. EVENTS OF DEFAULT

     8.1   Events of Default. Any of the following events shall be considered an
Event of Default under this Agreement:

     8.1.1 Payments. Borrowers' failure to make payment of any amount of the
Obligations within five (5) days after the date due.

     8.1.2 Representations and Warranties. Any representation or warranty made
by Borrowers or any other party in any Credit Document having been incorrect in
any material respect as of the date thereof.

     8.1.3 Negative Covenants. The failure of Borrowers to comply with any of
the requirements of Article VI hereof; provided, however, as to any such event
that is both (i) the result of an act by a third party absent the cooperation of
any Consolidated Entity, and (ii) reasonably susceptible to being cured, the
event shall not constitute an Event of Default unless the event remains uncured
for a period of twenty (20) days following the earlier of (i) Borrowers'
knowledge of the facts giving rise thereto or (ii) Agent's written notice to
Borrowers given in accordance with the provisions hereof.

     8.1.4 Financial Covenants. The failure of Borrowers to comply with any of
the requirements of Article VII hereof.

     8.1.5 Reporting Requirements. The failure of Borrowers or any other party
to timely perform any covenant in the Credit Documents requiring the furnishing
of notices, financial reports or other information to Lenders within five (5)
Business Days of when due; and provided, however, that during any period of time
that a report is delinquent, Agent may at its option increase the Pricing Values
to their highest levels permitted under this Agreement.

     8.1.6 Other Covenants. The failure of Borrowers to observe or perform any
covenant contained in any Credit Document, which covenant is not subject to any
specific provision in this Article VIII; provided, however, as to any such
breach that is reasonably susceptible to being cured, the occurrence of such
breach shall not constitute an Event of Default hereunder if such breach is
fully cured within twenty (20) days after the earlier of Borrowers' knowledge of
the facts giving rise thereto or Agent's written notice thereof to Borrowers
given in accordance with the provisions hereof.

     8.1.7 Involuntary Bankruptcy or Receivership Proceedings. The appointment
of a receiver, custodian, liquidator, or trustee for any Consolidated Entity, or
for any of its Property, by the order or decree of any court or agency or
supervisory authority having jurisdiction; or a Consolidated Entity's
adjudication as being bankrupt or insolvent; or the sequestering of any of the
Property of any Consolidated Entity by court order or the filing of a petition
against a Consolidated Entity under any state or federal bankruptcy,
reorganization, debt arrangement, insolvency, readjustment of debt, dissolution,
liquidation, or receivership law of any jurisdiction, whether now or hereafter
in effect, and in each case without the acquiescence of a Consolidated Entity,
unless dismissed within sixty (60) days.

     8.1.8 Voluntary Petitions. Any Consolidated Entity's filing of a petition
in voluntary bankruptcy or to seek relief under any provision of any bankruptcy,
reorganization, debt arrangement, insolvency, receivership, readjustment of
debt, dissolution, or liquidation law of any

                                       51
<PAGE>   53

jurisdiction, whether now or hereafter in effect, or its acquiescence in the
filing of any petition against it under any such law.

     8.1.9 Discontinuance of Business. Any Consolidated Entity's discontinuance
of its usual business, its dissolution or termination of Service Agreements
which, over a twelve-month period, either individually or cumulatively, account
for more than (i) ten percent (10%) (so long as Borrowers maintain a ratio of
Total Funded Debt to Consolidated EBITDA of less than or equal to 2.00 to 1.00)
or (ii) at all other times, five percent (5%) of Response's Consolidated EBITDA
for the previous twelve months, except pursuant to transactions permitted under
this Agreement.

     8.1.10 Default on Other Liabilities. Any Consolidated Entity's failure to
make any payment when due on (i) any Liabilities in excess of Five Hundred
Thousand and No/100 Dollars ($500,000.00) or (ii) any Subordinated Debt.

     8.1.11 Undischarged Judgments. The existence of a final judgment or
judgments for the payment of money in excess of Five Hundred Thousand and No/100
Dollars ($500,000.00) by any court or other Governmental Authority against a
Consolidated Entity, which is not paid, discharged, stayed, dismissed through
appropriate appellate proceedings or bonded within thirty (30) days after entry.

     8.1.12 Insolvency. Any Consolidated Entity's no longer being Solvent.

     8.1.13 Attachment. The issuance of an attachment or other process against
any Property of any Consolidated Entity, unless removed (by bond or otherwise)
within twenty (20) days.

     8.1.14 Insurance. Any Consolidated Entity's failure to maintain any
insurance required herein or in any other Credit Document.

     8.1.15 Contest. Any Consolidated Entity's challenge or contest of the
validity or enforceability of this Agreement or any other Credit Document or the
validity, priority or perfection of any security interest created hereunder or
under any other Credit Document in any action, suit or proceeding.

     8.1.16 Fraud and Abuse Laws. Receipt by one or more Consolidated Entities
of a notice from a Governmental Authority that it (i) intends to disallow
requested reimbursements, demand adjustment or repayment of past reimbursements
in excess of one-half of one percent (1/2 %) of the gross revenues of Borrowers
for the previous four (4) fiscal quarters in the aggregate respecting amounts
submitted for reimbursement or collected by Borrowers or a Provider, or (ii)
intends to impose civil money penalties or to seek to exclude Borrowers or a
Provider from participation in the Medicare or Medicaid programs due to a
failure to comply with Fraud and Abuse Laws, if the gross revenues to Borrower
arising from Borrowers or Provider exceed one-half of one percent (1/2%) of the
gross revenues of Borrowers for the previous four (4) fiscal quarters in the
aggregate.

     8.2   Remedies. Upon the happening of any Event of Default:

     8.2.1 Default Rate. Agent may declare the Obligations to thereafter bear
interest at the Default Rate.

     8.2.2 Termination of Commitments. As provided in Article III hereof,
Lenders shall not be obligated to advance any additional Loans and the Issuing
Bank shall not be obligated to issue


                                       52
<PAGE>   54

Letters of Credit. Agent may terminate the obligation of (i) Lenders to advance
any additional Loans and (ii) the Issuing Bank to issue Letters of Credit by
written notice to Borrowers, which formal termination shall remain in effect
notwithstanding any subsequent cure of the Event of Default and whether or not
the Loans are accelerated.

     8.2.3 Acceleration. Agent may declare the entire principal amount of all
Obligations then outstanding, including interest accrued thereon, to be
immediately due and payable without presentment, demand, protest, notice of
protest, or dishonor or other notice of default of any kind, all of which are
hereby expressly waived.

     8.2.4 Setoff. Any Lender may exercise its lien upon and right of setoff
against any monies, items, credits, deposits or instruments that such Lender may
have in its possession and which belong to Borrower or to any other person or
entity liable for the payment of any or all of the Obligations.

     8.2.5 Other Remedies. Lenders and Agent may exercise any right that they
may have under any other document evidencing or securing the Obligations or
otherwise available to Lenders or Agent at law or equity.

     8.2.6 Attorney-in-Fact. Borrowers hereby irrevocably appoint Agent as
Borrowers' attorney-in-fact to take any action to facilitate Agent's exercise of
remedies hereunder.

     8.2.7 Letters of Credit. At the option of the Required Lenders, the Issuing
Bank and the Agent may treat all then outstanding Letters of Credit as if drafts
in the full amount available to be drawn thereunder had been properly drawn
thereunder and paid by the Issuing Bank and the Borrowers had failed or refused
to reimburse the Issuing Bank for the amount so paid within the time permitted
under this Agreement. The Borrowers shall, promptly upon demand of the Agent,
deposit in cash with the Agent an amount equal to the amount of all Letter of
Credit Liabilities then outstanding, as collateral security for the repayment
thereof, which deposit shall be held by the Agent under the provisions of
Section 10.27.

                                    IX. AGENT

     9.1   Appointment of Agent. Lenders hereby appoint Agent to act as
specified in this Article IX. Agent's duties hereunder are administrative and
ministerial in nature, and Agent's capacity is that of an independent contractor
for Lenders. Agent is not a trustee or other fiduciary for Lenders, and Agent
has no duties whatsoever to Lenders except as expressly set forth in this
Agreement.

     9.2   Powers of Agent.

     9.2.1 Administration of Loans. Except as otherwise provided in this Section
9.2, Agent shall have the exclusive power and authority to (i) give all consents
and approvals, issue waivers and amendments, enforce the Credit Documents
(including, but not limited to, the power to enforce the Credit Documents in any
relevant case under the Bankruptcy Code) and otherwise take all actions
permitted of Agent under this Agreement or any other Credit Document, (ii) give
all consents and approvals, issue waivers and amendments, enforce the Credit
Documents (including, but not limited to, the power to enforce the Credit
Documents in any relevant case under the Bankruptcy Code) and otherwise take all
actions permitted of Lenders under this Agreement or any other Credit Document,
excepting only those matters that the Credit Documents specifically reserve for
the respective Lenders severally (such as the computation of LIBOR charges
unique

                                       53
<PAGE>   55

to the circumstances of a given Lender), (iii) receive all payments, notices and
other deliveries and communications to be given Lenders or Agent under this
Agreement or any other Credit Document, and (iv) to perform such actions as are
incidental to any of the foregoing.

     9.2.2 Matters Reserved to Required Lenders. Absent the prior approval of
the Required Lenders, Agent shall not waive or amend any covenant set forth in
this Agreement or approve any acquisition for which approval is necessary under
the definition of Permitted Acquisitions set forth in Article I hereof.

     9.2.3 Matters Reserved to all Lenders. Absent the prior approval of all
Lenders, Agent shall not forgive any principal included in the Obligations;
waive or amend any interest rate applicable to the Obligations; waive or amend
the Maturity Date; waive or amend the amount of any Lender's Commitment; release
or subordinate any security interest securing the Obligations (other than
releases thereof in connection with transactions for which the approval of
Lenders and/or Agent is not required, such as the release of pledged stock of a
Subsidiary in connection with the merger of that Subsidiary into another
Subsidiary); waive an Event of Default arising from non-payment of any principal
or interest due on the Obligations; accelerate the maturity of the Obligations;
or amend the definitions of Pro Rata Share or Required Lenders.

     9.3   Duties of Agent.

     9.3.1 Specific Duties of Agent: Standard of Care. Agent shall (i) remit to
each Lender, with reasonable promptness, the appropriate Pro Rata Share of
payments received or other amounts collected on account of the Obligations, (ii)
forward to Lenders, with reasonable promptness, counterparts or copies of
Borrowing Notices, financial reports and other information that may be delivered
to Agent by Borrower pursuant to the requirements of the Credit Documents, (iii)
notify Lenders of any Unmatured Default or Event of Default known to Agent, in
accordance with Section 9.7 below, and (iv) otherwise administer the Loans
through the exercise of such of the powers granted herein as Agent deems
appropriate from time to time. Agent shall have no liability to Lenders for any
action or inaction relating to this Agreement or the other Credit Documents,
except for actual losses caused by its gross negligence or reckless or willful
misconduct.

     9.3.2 Limitations on Agent's Duties. Agent shall not be obligated to take
any action hereunder or under any other Credit Document (i) if such action
would, in the opinion of Agent, be contrary to applicable law, this Agreement or
the other Credit Documents, (ii) if it shall not first be specifically
indemnified to its satisfaction against any and all liability and expense that
may be incurred by it by reason of taking or continuing to take any such action,
(iii) if it would likely subject Agent to a tax in any jurisdiction where it is
not then subject to a tax, (iv) if it would likely require Agent to qualify to
do business in any jurisdiction where it is not then so qualified, unless Agent
receives security or indemnity satisfactory to it against any tax or other
liability in connection with such qualification or resulting from the taking of
such action in connection therewith, or (v) if it would likely subject Agent to
in personam jurisdiction in any location where it is not then so subject.

     9.3.3 Agent's Right to Require Instructions in Performance of Duties. If
Agent, in its sole and absolute discretion, requests instructions from the
Required Lenders with respect to any act or action (including the failure to
act) in connection with this Agreement or any other Credit Document for which
the approval of the Required Lenders or all Lenders is not otherwise required,
Agent shall be entitled, at its option, to refrain from such action, or to
continue such inaction, unless and until Agent shall have received such
instructions, and Agent shall incur no liability by reason of so acting or
refraining from action. No Lender shall have any right of action

                                       54
<PAGE>   56

whatsoever against Agent as a result of Agent's acting or refraining from acting
hereunder or under any other Credit Document in accordance with the instructions
of the Required Lenders in such a case.

     9.3.4 Agent's Reliance on Others in Performance of Duties. Agent shall be
entitled to rely, and shall be fully protected in relying, upon any note,
writing, resolution, notice, statement, consent, certificate, telex, teletype or
facsimile message, order or other documentary, teletransmission or telephone
message believed by it in good faith to be genuine and correct and to have been
signed, sent or made by the proper Person. Agent may consult with legal counsel
(including counsel for Borrowers), accountants and other experts selected by it
with respect to all matters pertaining to this Agreement and the other Credit
Documents and its duties hereunder and thereunder and shall not be liable for
any action taken or omitted to be taken by it in good faith in accordance with
the advice of such counsel (including counsel for Borrowers), accountants or
experts.

     9.3.5 Sharing of Information. Except as otherwise expressly provided in
this Article IX, Agent shall have no duty or responsibility, either initially or
on a continuing basis, to provide any Lender with any credit or other
information concerning the business, prospects, operations, properties,
financial or other condition or creditworthiness of the Consolidated Entities or
any other Person that may come into its possession, whether before the making of
the initial Loans or at any time or times thereafter. All notices to be given to
Borrowers by a Lender hereunder shall be concurrently given to Agent and all
other Lenders.

     9.4   Indemnification of Agent. To the extent Agent is not reimbursed by or
on behalf of Borrowers, and without limiting the obligation of Borrowers to do
so, Lenders will reimburse and indemnify Agent, from and against any and all
liabilities, obligations, losses, damages, penalties, actions, judgments, suits,
costs, expenses (including attorneys' fees and expenses) or disbursements of any
kind or nature whatsoever that may at any time (including at any time following
the indefeasible repayment in full of the Loans) be imposed on, incurred by or
asserted against Agent in any way relating to or arising out of this Agreement
or any other Credit Document or the transactions contemplated thereby or any
action taken or omitted by Agent under or in connection with any of the
foregoing, and in particular will reimburse Agent for out-of-pocket expenses
promptly upon demand by Agent therefor; provided, however, that no Lender shall
be liable for any portion of such liabilities, obligations, losses, damages,
penalties, actions, judgments, suits, costs, expenses or disbursements finally
determined by a court of competent jurisdiction and not subject to any appeal or
pursuant to arbitration to have resulted from Agent's gross negligence or
reckless or willful misconduct. Agent may offset any amounts due Agent by any
Lender against obligations of Agent to that Lender.

     9.5   No Representations by Agent. Each Lender acknowledges that neither
Agent nor any of its officers, directors, employees, attorneys, accountants or
agents has made any representation or warranty to it regarding the Consolidated
Entities, the Loans, the Collateral or otherwise relating to this Agreement.
Agent shall not be responsible to any Lender for any recitals, statements,
information, representations or warranties herein or in any other Credit
Document or in any document, instrument, certificate or other writing delivered
in connection herewith or therewith or for the execution, effectiveness,
genuineness, validity, enforceability, perfection, priority or sufficiency of
this Agreement or any other Credit Document or the financial condition of the
Consolidated Entities or any other Person, or be required to make any inquiry
concerning either the performance or observance of any of the terms, provisions
or conditions of this Agreement or any other Credit Document, or the financial
condition of the Consolidated Entities

                                       55
<PAGE>   57
or any other Person or the existence or possible existence of any Unmatured
Default or Event of Default.

     9.6   Independent Investigations by Lenders. Each Lender acknowledges that,
independently and without reliance upon Agent or any other Lender and based on
such documents and information as it has deemed and may deem appropriate, (i) it
has made its own appraisal of and investigation into the business, prospects,
operations, properties, financial and other condition and creditworthiness of
the Consolidated Entities in connection with its decision to enter into this
Agreement and extend credit to Borrowers hereunder, and (ii) it will continue to
make its own credit analysis, appraisals and decisions in taking or not taking
action hereunder.

     9.7   Notice of Default. Agent shall not be deemed to have knowledge or
notice of the occurrence of any Unmatured Default or Event of Default, other
than any Unmatured Default or Event of Default arising out of the failure to pay
any principal, interest, fees or other amounts payable to Agent for the account
of Lenders, unless Agent has received written notice from Borrowers or a Lender
describing such Unmatured Default or Event of Default and stating that such
notice is a "notice of default." In the event that Agent receives such a notice,
Agent shall give notice thereof to Lenders as soon as reasonably practicable;
provided, however, that if any such notice has also been furnished to Lenders,
Agent shall have no obligation to notify Lenders with respect thereto. Each
Lender shall promptly give Agent such a notice upon its actual knowledge of an
Unmatured Default or an Event of Default; provided, however, that the failure of
any Lender to deliver such notice in the absence of gross negligence or reckless
or willful misconduct shall not affect its rights hereunder or under the other
Credit Documents.

     9.8   Funding of Loans Pursuant to Borrowing Notices. Promptly following
receipt of notice from Agent that a Borrowing Notice has been submitted, and
provided that all conditions to funding are believed to have been satisfied,
each Lender shall transfer to a designated account with Agent that Lender's Pro
Rata Share of the requested funding. The transfer of funds shall occur within
the time required for funding under this Agreement; provided, however, no Lender
shall be obligated to fund a LIBOR Loan earlier than two (2) Business Days after
its receipt of notice of the borrowing from Agent. Should any Lender fail to
timely fund its Pro Rata Share of a requested Loan, Agent may, but shall be
under no obligation whatsoever to, advance to Borrowers the defaulted Lender's
Pro Rata Share of the requested Loan. If such an advance is made, it shall be
deemed an advance by Agent for the account of the defaulting Lender and shall
bear interest at the rate applicable to the Loan funded by the advance, payable
on demand.

     9.9   Agent in its Individual Capacity. With respect to its Commitments,
and the Loans made by it, Agent shall have the same rights and powers under the
Credit Documents as any other Lender or holder of a Note and may exercise the
same as though it were not performing the duties specified herein; and the terms
"Lenders," "Required Lenders," and any similar terms shall, unless the context
clearly otherwise indicates, include Agent in its individual capacity as a
Lender. Agent may accept deposits from, lend money to and generally engage in
any kind of banking, trust, financial advisory or other business with the
Consolidated Entities or any of their respective Affiliates as if it were not
performing the servicing duties specified herein, and may accept fees and other
consideration from Borrowers for services in connection with this Agreement and
otherwise without having to disclose or account for the same to Lenders.

     9.10 Holders. Agent may deem and treat the payee of any Note as the holder
thereof and Lender hereunder for all purposes hereof unless and until a written
notice of the assignment, transfer or endorsement thereof purportedly executed
by the payee, as the case may be, shall have been filed with Agent. Any request,
authority or consent of any Person that, at the time of making

                                       56
<PAGE>   58

such request or giving such authority or consent, is the holder of any Note
according to Agent's information, shall be conclusive and binding on any
subsequent holder, transferee, assignee or endorsee, as the case may be, of such
Note or of any Note or Notes issued in exchange therefor.

     9.11 Successor Agent. Agent may resign at any time upon sixty (60) days'
prior written notice to Borrowers and Lenders. Agent may be removed upon Agent's
insolvency, liquidation or the appointment of a receiver for Agent, by action of
the Required Lenders, at any time upon sixty (60) days' prior written notice to
Borrowers and Agent. Such resignation or removal, as the case may be, shall take
effect upon the appointment of a successor Agent as provided herein. The
Required Lenders will appoint from among Lenders a successor Agent. If no
successor Agent shall have been appointed within such sixty (60) day period,
Agent may appoint, after consulting with Lenders and Borrowers, a successor
agent from among Lenders, who shall serve as Agent until such time, if any, as
the Required Lenders shall have appointed a successor Agent as provided
hereinabove. Upon the written acceptance of any appointment as Agent hereunder
by a successor Agent, such successor Agent shall thereupon succeed to and become
vested with all the rights, powers, privileges and duties of the retiring Agent,
and the retiring Agent shall be discharged from its duties and obligations
hereunder and under the other Credit Documents. After any retiring Agent's
resignation as Agent, the provisions of this Article shall inure to its benefit
as to any actions taken or omitted to be taken by it while it was Agent.

     9.12 Sharing of Payments. etc. Each Lender agrees that if it shall, through
the exercise of a right of banker's lien, set-off, counterclaim or otherwise,
obtain payment with respect to the Obligations which results in its receiving
more than its Pro Rata Share of the aggregate payments with respect to all of
the Obligations, then (a) such Lender shall be deemed to have simultaneously
purchased from the other Lenders a share in the Obligations so that the amount
of the Obligations held by each of Lenders shall continue to equal their
respective Pro Rata Shares, and (b) such other adjustments shall be made from
time to time as shall be equitable to insure that Lenders share such payments
ratably. No Lender shall exercise its banker's lien, set-off or other right to
accomplish such payment absent Agent's prior consent.

     9.13 Separate Liens on Collateral. Each Lender agrees with the other
Lenders that, with the exception of security interests in deposit accounts and
like property in the possession of a Lender as expressly provided for in this
Agreement, it will not take or permit to exist any Encumbrance in its favor on
any of the Collateral or other property of any of the Consolidated Entities
other than Encumbrances securing the Obligations due to all Lenders pursuant to
the Credit Documents.

     9.14 Payments Between Agent and Lenders. All payments by Agent to any
Lender, and all payments by any Lender to Agent, under the terms of this
Agreement shall be made by wire transfer in immediately available funds to the
receiving party's address specified for notices in this Agreement. If any of
Lenders fail to pay when due any sum payable to Agent, then, except as otherwise
provided in Section 9.8 hereof, such sum shall bear interest until paid at the
interest rate per annum for overnight borrowing by the payee from the Federal
Reserve Bank for the period commencing on the date such payment was due and
ending on, but excluding, the date such payment is made.

     9.15 Assignment Approvals. Absent the approval of the other Lenders, no
Lender shall assign its interest in the Loans without first offering to sell
such Lender's interest to the other Lenders to be closed Pro Rata to the
Lender(s) who may elect to purchase such interest. Such offers to sell shall be
made in writing, shall provide the other Lenders ten (10) Business Days to
accept or reject, and shall allow an additional ten (10) Business Days to close.

                                       57
<PAGE>   59

     9.16 Bankruptcy Provisions. Should any of the Consolidated Entities become
a party to a case under the Bankruptcy Code, each Lender shall be entitled to
file its own claim, to the extent such a filing may be necessary. Agent shall
review each claim before being filed by a Lender to assure that the claim is
filed on a basis consistent with Agent's records and Agent's legal positions
taken pursuant to this Agreement. Should any of the Consolidated Entities become
a party to a reorganization proceeding under the Bankruptcy Code, each Lender
shall be recognized as the holder of a separate claim for the purpose of the
approval or rejection of a Plan under 11 U.S.C. ss. 1126, may freely vote such
claim, and the provisions of that Section shall control the other provisions of
this Agreement that otherwise require the consent of the Required Lenders or all
Lenders in certain circumstances. Agent shall continue to administer the
Revolving Credit Loan on behalf of Lenders, as they may be amended by any
adopted Plan of Reorganization.

     9.17 Foreclosure of Collateral. In the event of a foreclosure of any
Collateral, Agent may issue a credit bid for the account of all Lenders, up to
the amount of the then outstanding Obligations. Any Property acquired at such a
foreclosure (or acquired by Agent through a conveyance in lieu of foreclosure)
shall be held and administered by Agent for the benefit of all Lenders pursuant
to the terms of this Article IX.

     9.18 Procedures for Notices and Approvals. All notices given among Lenders
and Agent with respect to this Agreement or the other Credit Documents shall be
given in the manner provided in this Agreement. Additionally, should Agent
request Lenders' approval of any matter, each Lender shall respond in writing
within five (5) Business Days after the Business Day on which the request was
received. If a Lender fails to so respond, it shall be deemed to have approved
the action proposed by Agent.

     9.19 Amendments to Article IX. No provision of this Article IX may be
amended or waived absent the prior written consent of all Lenders and Agent.
Borrower's approval shall not be required for the amendment or waiver of any
provision of this Article IX; provided, however, Borrowers' written consent
shall be required for any amendment of this Article IX that would eliminate the
position of Agent.

                              X. GENERAL PROVISIONS

     10.1 Notices. All communications relating to this Agreement or any of the
other Credit Documents shall be in writing and shall effective when be delivered
by mail, overnight courier, special courier, telecopier or otherwise to the
following addresses:

         If to Borrower:

         c/o Response Oncology, Inc.
         Attn:  Mary E. Clements
         1805 Moriah Woods Blvd.
         Memphis, Tennessee 38117
         Telecopier:       (901) 763-7045

                                      58
<PAGE>   60

         With a Copy To:

         Baker, Donelson, Bearman & Caldwell
         Attn:  Mary Aronov, Esq.
         First Tennessee Building
         165 Madison Avenue, Suite 2000
         Memphis, Tennessee 38103
         Telecopier:       (901) 577-2303

         If to AmSouth or Agent:

         AmSouth Bank
         Attn:  Cathy Wind
         333 Union Street, Suite 200
         Nashville, Tennessee  37201
         Telecopier:  (615) 291-5257

         With a Copy To:

         Maynard, Cooper & Gale, P.C.
         Attn:  J. Kris Lowry, Esq.
         1901 6th Avenue North
         2400 AmSouth/Harbert Plaza
         Birmingham, Alabama  35203-2618
         Telecopier:       (205) 254-1999

     If to the other Lenders, at the address set forth on the signature pages
attached hereto. Any party may change its address for receipt of notice by
written direction to the other parties hereto.

     10.2 Renewal, Extension, or Rearrangement. All provisions of this Agreement
relating to Obligations shall apply with equal force and effect to each and all
promissory notes executed hereafter which in whole or in part represent a
renewal, extension for any period, increase, or rearrangement of any part of the
Obligations originally represented by any part of such other Obligations.

     10.3 Application of Payments. Amounts received with respect to the
Obligations shall be applied (i) first, to any expenses due Lenders or Agent,
(ii) second, to accrued and unpaid interest under any of the Obligations, (iii)
third, to reduce the unpaid principal portion of the Obligations (other than
those arising from Hedge Agreements) in such manner as determined by Agent, and
(iv) fourth, to any Obligations arising under Hedge Agreements (apportioned pro
rata among them if more than one).

     10.4 Counterparts. This Agreement may be executed in counterparts with all
signatures or by counterpart signature pages, and it shall not be necessary that
the signatures of all parties be contained on any one counterpart. Each
counterpart shall be deemed an original, but all of them together shall
constitute one and the same instrument.

     10.5 Negotiated Document. This Agreement and the other Credit Documents
have been negotiated by the parties with full benefit of counsel and should not
be construed against any party as author.

                                       59
<PAGE>   61

     10.6 Consent to Jurisdiction: Exclusive Venue. Borrower hereby irrevocably
consents to the jurisdiction of the United States District Court for the Middle
District of Tennessee and of all Tennessee state courts sitting in Davidson
County, Tennessee, for the purpose of any litigation to which Lenders or Agent
may be a party and which concerns this Agreement or the Obligations. It is
further agreed that venue for any such action shall lie exclusively with courts
sitting in Davidson County, Tennessee, unless Lenders and Agent agree to the
contrary in writing. This election applies only for the limited judicial
proceedings that may apply as set forth in the provision of this Agreement
electing binding arbitration for the resolution of disputes and does not impair
the effect of that provision in any way.

     10.7 Not Partners: No Third Party Beneficiaries. The relationship of
Lenders and Borrowers is that of lenders and borrowers only, and neither is a
fiduciary, partner or joint venturer of the other for any purpose. This
Agreement has been executed for the sole benefit of Lenders, and no third party
is authorized to rely upon Lenders' rights or duties hereunder.

     10.8 No Reliance on Lenders' Analysis. Borrowers acknowledge and represent
that, in connection with the Obligations, Borrowers have not relied upon any
financial projection, budget, assessment or other analysis by Lenders or Agent
upon any representation by Lenders as to the risks, benefits or prospects of
Borrowers' business activities or present or future capital needs incidental
thereto, all such considerations having been examined fully and independently by
Borrowers.

     10.9 No Marshaling of Assets. Lenders and Agent may proceed against
collateral securing the Obligations and against parties liable therefor in such
order as they may elect, and neither Borrowers nor any surety or guarantor for
Borrowers nor any creditor of Borrowers shall be entitled to require Lenders or
Agent to marshal assets. The benefit of any rule of law or equity to the
contrary is hereby expressly waived.

     10.10 Impairment of Collateral. Lenders or Agent may, in their sole
discretion, release any Collateral securing the Obligations or release any party
liable therefor. The defenses of impairment of collateral and impairment of
recourse and any requirement of diligence in collecting the Obligations are
hereby waived.

     10.11 Business Days. If any payment date under the Obligations falls on a
day that is not a Business Day, or if the last day of any notice period falls on
such a day, the payment shall be due and the notice period shall end on the next
following Business Day.

     10.12 Participations and Assignments.

     (a) Lenders may, from time to time, in their sole discretion, and with
concurrent notice to Borrower, sell participations in any credit subject hereto
to such other investors or financial institutions as it may elect. Lenders and
Agent may from time to time disclose to any participant or prospective
participant such information as they may have regarding the financial condition.
operations, and prospects of Borrower.

     (b) At any time after the Closing Date each Lender may (subject to the
terms of Section 9.15), with the prior consent of the Agent and the Borrowers,
which consent shall not be unreasonably withheld, assign to one or more banks or
financial institutions all or a portion of its rights and obligations under this
Agreement (including all or a portion of the Note payable to its order);
provided, that (i) each such assignment shall be of a constant, and not a
varying, percentage of all of the assigning Lender's rights and obligations
under this Agreement, (ii) for

                                       60
<PAGE>   62

each assignment involving the issuance and transfer of Notes, the assigning
Lender shall execute an Assignment and Acceptance and the Borrowers hereby
consent to execute a replacement Note or Notes to give effect to the assignment,
(iii) the minimum commitment which shall be assigned is $5,000,000 (together
with which the assigning Lender's applicable portion of the Letter of Credit
Liabilities shall also be assigned) and (iv) such assignee shall have an office
located in the United States. Upon such execution, delivery, approval and
acceptance, from and after the effective date specified in each Assignment and
Acceptance (x) the assignee thereunder shall be a party hereto and, to the
extent that rights and obligations hereunder or under such Note or Notes have
been assigned or negotiated to it pursuant to such Assignment and Acceptance,
have the rights and obligations of a Lender hereunder, as fully as if such
assignee had been named as a Lender in this Agreement, and of a holder of such
Note or Notes, and (y) the assignor shall, to the extent that rights and
obligations hereunder or under such Note or Notes have been assigned or
negotiated by it pursuant to such Assignment and Acceptance, relinquish its
rights and be released from its future obligations under this Agreement. No
assignee shall have the right to make any further assignment of its rights and
obligations pursuant to this Agreement. Any Lender that makes an assignment
shall pay to the Agent a one-time administrative fee of $5,000, which fee shall
not be reimbursed by Borrowers.

     (c) By executing and delivering an Assignment and Acceptance, the
Lender-assignor and the assignee thereunder confirm to and agree with each other
and the other parties hereto as follows: (i) the assignment made under such
Assignment and Acceptance is made under such Assignment and Acceptance without
recourse; (ii) such assignor makes no representation or warranty and assumes no
responsibility with respect to the financial condition of the Borrowers or any
other person or the performance or observance by the Borrowers or any other
person of any of its obligations under any Credit Document or any other
instrument or document furnished pursuant hereto; (iii) such assignee confirms
that it has received a copy of this Agreement, together with copies of all
financial statements delivered pursuant to this Agreement, and such other Credit
Documents and other documents and information as it has deemed appropriate to
make its own credit analysis and decision to enter into such Assignment and
Acceptance; (iv) such assignee will, independently and without reliance upon the
Agent, the assignor or any other Lender and based on such documents and
information as it shall deem appropriate at the time, continue to make its own
credit decisions in taking or not taking action under this Agreement; (v) such
assignee appoints and authorizes the Agent to take such action as agent on its
behalf and to exercise such powers under this Agreement, the Note and the other
Credit Documents as are delegated to the Agent by the terms hereof and thereof,
together with such powers as are reasonably incidental thereto; and (vi) such
assignee agrees that it will perform in accordance with their terms all of the
obligations which by the terms of this Agreement are required to be performed by
it as a Lender and a holder of such Note.

     (d) The Agent shall maintain at its address referred to herein a copy of
each Assignment and Acceptance delivered to and accepted by it.

     (e) Upon its receipt of an Assignment and Acceptance executed by an
assigning Lender, the Agent shall give prompt notice thereof to the Borrowers.

     10.13 Standard of Care: Limitation of Damages. Lenders and Agent shall be
liable to Borrowers only for matters arising from this Agreement or otherwise
related to the Obligations resulting from such Lender's or Agent's gross
negligence or reckless or willful misconduct, and liability for all other
matters is hereby waived. Lenders and Agent shall not in any event be liable to
Borrowers for special or consequential damages arising from this Agreement or
otherwise related to the Obligations.

                                       61
<PAGE>   63

     10.14 Incorporation of Schedules. All Schedules and Exhibits referred to in
this Agreement are incorporated herein by this reference.

     10.15 Indulgence Not Waiver. Lenders' or Agent's indulgence in the
existence of a default hereunder or any other departure from the terms of this
Agreement shall not prejudice Lenders' or Agent's rights to declare a default or
otherwise demand strict compliance with this Agreement.

     10.16 Cumulative Remedies. The remedies provided Lenders and Agent in this
Agreement are not exclusive of any other remedies that may be available to
Lenders and Agent under any other document or at law or equity.

     10.17 Amendment and Waiver in Writing. No provision of this Agreement can
be amended or waived, except by a statement in writing signed by the party or
parties against whom enforcement of the amendment or waiver is sought. Waivers
and amendments may be executed by Agent on behalf of Lenders, subject to the
requirements of Article IX hereof requiring the consent of some or all of
Lenders under certain circumstances.

     10.18 Assignment. This Agreement shall be binding upon and inure to the
benefit of the respective successors and assigns of Borrowers and Lenders,
except that Borrowers shall not assign any rights or delegate any obligations
arising hereunder without the prior written consent of Lenders. Any attempted
assignment or delegation by Borrowers without the required prior consent shall
be void.

     10.19 Entire Agreement. This Agreement and the other written agreements
among Borrowers, Lenders and Agent represent the entire agreement between the
parties concerning the subject matter hereof, and all oral discussions and prior
agreements are merged herein. Provided, if there is a conflict between this
Agreement and any other document executed contemporaneously herewith with
respect to the Obligations, the provisions in this Agreement shall control.

     10.20 Severability. Should any provision of this Agreement be declared
invalid or unenforceable for any reason, the remaining provisions hereof shall
remain in full effect.

     10.21 Time of Essence. Time is of the essence of this Agreement, and all
dates and time periods specified herein shall be strictly observed.

     10.22 Applicable Law. The validity, construction and enforcement of this
Agreement and all other documents executed with respect to the Obligations shall
be determined according to the laws of Tennessee applicable to contracts
executed and performed entirely within that state.

     10.23 Captions Not Controlling. Captions and headings have been included in
this Agreement for the convenience of the parties, and shall not be construed as
affecting the content of the respective Sections.

     10.24 Arbitration. Any controversy or claim between or among the parties
hereto including but not limited to those arising out of or relating to this
instrument, agreement or document or any related instruments, agreements or
documents, including any claim based on or arising from an alleged tort, shall
be determined by binding arbitration in accordance with the Federal Arbitration
Act (or if not applicable, the applicable state law), the Rules of Practice and
Procedure for the Arbitration of Commercial Disputes of J.A.M.S./Endispute or
any successor thereof ("J.A.M.S."), and the "Special Rules" set forth below. In
the event of any inconsistency, the Special Rules shall control. Judgment upon
any arbitration award may be entered in any court

                                       62
<PAGE>   64

having jurisdiction. Any party to this Agreement may bring an action, including
a summary or expedited proceeding, to compel arbitration of any controversy or
claim to which this Agreement applies in any court having jurisdiction over such
action.

     10.24.1 Special Rules. The arbitration shall be conducted in Nashville,
Tennessee and administered by J.A.M.S who will appoint an arbitrator; if
J.A.M.S. is unable or legally precluded from administering the arbitration, then
the American Arbitration Association will serve. All arbitration hearings will
be commenced within 90 days of the demand for arbitration; further, the
arbitrator shall only, upon a showing of cause, be permitted to extend the
commencement of such hearing for up to an additional 60 days.

     10.24.2 Reservation of Rights. Nothing in this arbitration provision shall
be deemed to (i) limit the applicability of any otherwise applicable statutes of
limitation or repose and any waivers contained in this arbitration provision; or
(ii) be a waiver by any Lender of the protection afforded to it by 12 U.S.C.
Sec. 91 or any substantially equivalent state law; or (iii) limit the right of
any Lender (a) to exercise self help remedies such as (but not limited to)
setoff, or (b) to foreclose against any real or personal property collateral, or
(c) to obtain from a court provisional or ancillary remedies such as (but not
limited to) injunctive relief, writ of possession or the appointment of a
receiver. Lenders and Agent may exercise such self help rights, foreclose upon
such property, or obtain such provisional or ancillary remedies before, during
or after the pendency of any arbitration proceeding brought pursuant to this
instrument, agreement or document. Neither this exercise of self help remedies
nor the institution or maintenance of an action for foreclosure or provisional
or ancillary remedies shall constitute a waiver of the right of any party,
including the claimant in such action, to arbitrate the merits of the
controversy or claim occasioning resort to such remedies.

     10.25 Facsimile Signatures. This Agreement may be executed by facsimile
signatures, and shall be effective when Agent has received telecopy
transmissions of the signature pages executed by all parties hereto; provided,
however, that all parties shall deliver original executed documents to Agent
promptly following the execution hereof.

     10.26 Obligations Absolute. Response hereby agrees that its obligations and
liabilities with respect to the Obligations are joint and several with the other
Borrowers (except as limited by the terms of Section 1.3 above and by the terms
of the Assumption Agreements executed by Participating Entities who become such
after the Closing Date), continuing, absolute and unconditional. Without
limiting the generality of the foregoing, the obligations and liabilities of
Response with respect to the Obligations shall not be released, discharged,
impaired, modified or in any way affected by (a) the invalidity or
unenforceability of any Credit Document executed by any other person with
respect to the Obligations, (b) the failure of the Agent or the Lenders to give
Response a copy of any notice given to any other person, (c) any modification,
amendment or supplement of any obligation, covenant or agreement contained in
any Credit Document executed by any other person with respect to the
Obligations, (d) any compromise, settlement, release or termination of any
obligation, covenant or agreement in any Credit Document executed with respect
to the Obligations, (e) any waiver of payment, performance or observance by or
in favor of any Participating Entities of any obligation, covenant or agreement
under any Credit Document, (f) any consent, extension, indulgence or other
action or inaction, or any exercise or non-exercise of any right, remedy or
privilege with respect to any Credit Document executed by any other person with
respect to the Obligations, (g) the extension of time for payment or performance
of any Obligation by any Participating Entities, or (h) the release or discharge
of the Lenders' claims against any Collateral now or at any time hereafter
securing any of the Obligations, or any Participating Entities by operation of
law or otherwise.

                                       63
<PAGE>   65

     10.27 Termination. The termination of this Agreement shall not affect any
rights of the Borrowers, the Lenders or the Agent or any obligation of the
Borrowers, the Lenders or the Agent, arising prior to the effective date of such
termination, and the provisions hereof shall continue to be fully operative
until all transactions entered into or rights created or obligations incurred
prior to such termination have been fully disposed of, concluded or liquidated
and the Obligations arising prior to or after such termination have been
irrevocably paid in full. The rights granted to the Agent for the benefit of the
Lenders hereunder and under the other Credit Documents shall continue in full
force and effect, notwithstanding the termination of this Agreement, until all
of the Obligations have been paid in full after the termination hereof or the
Borrowers have furnished the Lenders with an indemnification satisfactory to the
Lenders with respect thereto. All representations, warranties, covenants,
waivers and agreements contained herein shall survive termination hereof until
payment in full of the Obligations unless otherwise provided herein.
Notwithstanding the foregoing, if after receipt of any payment of all or any
part of the Obligations, the Agent or the Lenders are for any reason compelled
to surrender such payment to any Person because such payment is determined to be
void or voidable as a preference, impermissible setoff, a diversion of trust
funds or for any other reason, this Agreement shall continue in full force and
the Borrowers shall be liable to, and shall indemnify and hold the Agent and the
Lenders harmless for, the amount of such payment surrendered until the Agent and
the Lenders shall have been finally and irrevocably paid in full. The provisions
of the foregoing sentence shall be and remain effective notwithstanding any
contrary action which may have been taken by the Agent or the Lenders in
reliance upon such payment, and any such contrary action so taken shall be
without prejudice to the Agent's or the Lenders' rights under this Agreement and
shall be deemed to have been conditioned upon such payment having become final
and irrevocable. If on any date on which the Borrowers wish to pay the
Obligations in full and terminate this Agreement, there are any outstanding
Letters of Credit, the Borrowers shall, unless otherwise agreed by the Required
Lenders in their sole discretion, make a cash prepayment to the Agent on such
date in an amount equal to the then-outstanding Letter of Credit Liabilities,
and the Agent shall hold such prepayment in an interest-bearing cash collateral
account in the name and under the sole control of the Agent (which account shall
bear interest at the Agent's then-current rate for such accounts) as security
for the Reimbursement Obligations and other Letter of Credit obligations. To the
extent allowed by law, such account shall not constitute an asset of the
Borrowers, or any of them, subject to their rights therein under this Section
10.27. The Agent shall from time to time debit such account for the payment of
the Letter of Credit Liabilities as the same become due and payable and shall
promptly refund any excess funds (including interest) held in said account to
the Borrowers if and when no Letter of Credit Liabilities remain outstanding
hereunder and all of the Obligations have been paid in full. The Borrowers shall
remain liable for any Obligations in excess of the amounts paid from such
account.


                                       64
<PAGE>   66

Executed as of the date first written above.


                                    RESPONSE ONCOLOGY, INC.


                                    By:
                                       ----------------------------------------

                                         Title:
                                               --------------------------------


                                    RESPONSE ONCOLOGY MANAGEMENT OF SOUTH
                                    FLORIDA, INC.


                                    By:
                                       ----------------------------------------

                                         Title:
                                               --------------------------------


                                    RESPONSE ONCOLOGY OF TAMARAC, INC.


                                    By:
                                       ----------------------------------------

                                         Title:
                                               --------------------------------



                                    RESPONSE ONCOLOGY OF FORT LAUDERDALE, INC.


                                    By:
                                       ----------------------------------------

                                         Title:
                                               --------------------------------




<PAGE>   67



                             AMSOUTH BANK, as Lender and Swingline Lender


                             By:
                                ----------------------------------------

                                  Title:
                                        --------------------------------

                             Term Loan Commitment:  $11,692,200

                             Revolving Credit Commitment: $4,307,800

                             Lending Office, Hand Delivery and Mailing Address:

                             333 Union Street, Suite 200
                             Nashville, Tennessee  37201
                             FAX:  (615) 291-5257
                             Attention:  Cathy Wind





<PAGE>   68



                             UNION PLANTERS NATIONAL BANK, as a Lender


                             By:
                                ----------------------------------------

                                  Title:
                                        --------------------------------


                             Term Loan Commitment:  $7,307,800

                             Revolving Credit Commitment: $2,692,200


                             Lending Office, Hand Delivery and Mailing Address:

                             6200 Poplar Avenue
                             Memphis, Tennessee  38119
                             FAX:     (901) 580-5451
                             Attention:    Elizabeth Rouse




<PAGE>   69



                       NATIONSBANK, N.A., as a Lender


                       By:
                          ----------------------------------------

                            Title:
                                  --------------------------------


                       Term Loan Commitment:  $16,000,000


                       Lending Office, Hand Delivery and Mailing Address:

                       One NationsBank Plaza
                       Nashville, Tennessee  37239-1697
                       FAX:     (615) 749-4951
                       Attention:    Andrew Zimberg





<PAGE>   70



                                    AMSOUTH BANK, as Agent


                                    By:
                                       ----------------------------------------

                                         Title:
                                               --------------------------------









<PAGE>   71



                                TABLE OF CONTENTS
<TABLE>
<CAPTION>

                                                                                                               Page

<S>                                                                                                            <C>
RECITALS .......................................................................................................  1

I.       DEFINITIONS............................................................................................  1

         1.1 Terms Defined in This Agreement....................................................................  1
         1.2 Terms Generally.................................................................................... 17
                  1.2.1    Computations: Accounting Principles.................................................. 17
                  1.2.2    Gender and Number.................................................................... 17
                  1.2.3    References Include Successors........................................................ 17
                  1.2.4    References to this Agreement......................................................... 17
                  1.2.5    Limitations of Knowledge............................................................. 17
         1.3 Participating Entities............................................................................. 18
                  1.3.1    Attorney-in-Fact..................................................................... 18
                  1.3.2    Liability Limitation................................................................. 18
                  1.3.3    Informed Consent..................................................................... 19
                  1.3.4    Joint and Several Obligations........................................................ 19
                  1.3.5    Subrogation and Contribution Agreement............................................... 19
                  1.3.6    Assumption Agreement................................................................. 20

II.  LOANS...................................................................................................... 20

         2.1 Amount of Revolving Credit Loan.................................................................... 20
                  2.1(a)   Amount of Term Loan.................................................................. 20
         2.2 Use of Proceeds.................................................................................... 20
         2.3 Revolving Credit Loan Notes........................................................................ 20
                  2.3(a)   Term Loan Notes...................................................................... 21
         2.4 Separate Commitments of Lenders.................................................................... 21
         2.5 Advances of Loans.................................................................................. 21
                  2.5.1    Loans Advanced Pursuant to Borrowing Notices......................................... 21
                           2.5.1(a) Applicability............................................................... 21
                           2.5.1(b) Borrowing Notices........................................................... 21
                           2.5.1(c) Funding of Loans............................................................ 21
                           2.5.1(d) Prime Rate Loan Limitations................................................. 21
                           2.5.1(e) LIBOR Loan Limitations...................................................... 22
                           2.5.1(f) Additional Limitation on LIBOR Interest Periods............................. 22
                  2.5.2    Conversion of Loans.................................................................. 22
                           2.5.2(a) Application of Loans........................................................ 22
                           2.5.2(b) Notices of Conversions...................................................... 22
                  2.5.3 Absence of Election..................................................................... 22
                  2.5.4 Implied Representations Upon Request for Loan........................................... 22
                  2.5.5 Advance Not Waiver...................................................................... 22
                  2.5.6 Draws by Debit Memorandum............................................................... 23
         2.6 Interest........................................................................................... 23
                  2.6.1    Prime Rate Loans..................................................................... 23
                  2.6.2    LIBOR Loans.......................................................................... 23
                  2.6.3    Additional Interest on LIBOR Loans................................................... 23
                  2.6.4    Calculation of Interest.............................................................. 23
</TABLE>



                                      i

<PAGE>   72


<TABLE>
<CAPTION>


         <S>      <C>                                                                                            <C>
                  2.6.5    Default Rate......................................................................... 23
                  2.6.6    Payment of Interest.................................................................. 23
                  2.6.7    Usury Savings Provision.............................................................. 23
         2.7 Alternate Rate of Interest if LIBOR Unavailable.................................................... 24
         2.8 Change in Circumstances............................................................................ 24
                  2.8.1    Imposition of Requirements........................................................... 24
                  2.8.2    Other Changes........................................................................ 25
                  2.8.3    Computation of Amounts............................................................... 25
                  2.8.4    No Duty to Contest................................................................... 25
         2.9 Change in Legality of LIBOR Loans.................................................................. 26
         2.10 Principal Repayment............................................................................... 26
         2.11 Prepayment of LIBOR Loans......................................................................... 27
                  2.11.1   Notice of LIBOR Loan Prepayment...................................................... 27
                  2.11.2   Amount of LIBOR Loan Prepayment...................................................... 27
                  2.11.3   LIBOR Loan Prepayment Premium........................................................ 27
         2.12 Prepayment of Prime Rate Loans.................................................................... 28
         2.13 Fixed Commitment Fees............................................................................. 28
         2.14 Periodic Commitment Fee Based on Use of Facilities................................................ 28
         2.15 Agent's Fee....................................................................................... 28
         2.16 Letters of Credit................................................................................. 28
                  2.16.1   Procedure for Issuance............................................................... 28
                  2.16.2   Participation Among Lenders.......................................................... 29
                  2.16.3   Reimbursement Obligation............................................................. 29
                  2.16.4   Means of Reimbursement............................................................... 30
                  2.16.5   Payments by Lenders.................................................................. 30
                  2.16.6   Settlement Among Lenders............................................................. 30
                  2.16.7   Letter of Credit Fee................................................................. 31
                  2.16.8   Letter of Credit Information......................................................... 31
                  2.16.9   Conditions Relating to Letters of Credit............................................. 31
                  2.16.10           Payments Among Lenders...................................................... 31
                  2.16.11           Modifications............................................................... 31
                  2.16.12           Absolute Obligations of Borrowers........................................... 32
                  2.16.13           Indemnification............................................................. 33
                  2.16.14           Assumption of Risk.......................................................... 33
                  2.16.15           Reserves.................................................................... 34
         2.17     Swingline Loans............................................................................... 34
                  2.17.1   Use of Proceeds of Swingline Loans................................................... 34
                  2.17.2   Swingline Note....................................................................... 34
                  2.17.3   Funding of Swingline Loans Advanced Pursuant to
                           Borrowing Notices.................................................................... 35
                           2.17.3(a) Applicability.............................................................. 35
                           2.17.3(b) Borrowing Notices.......................................................... 35
                           2.17.3(c) Funding of Swingline Loans................................................. 35
                  2.17.4   Funding of Swingline Loans Advanced Pursuant to Cash
                           Management Accounts.................................................................. 35
                           2.17.4(a)        Funding and Payment Procedures Controlled by
                                            Account Agreements.................................................. 35
                           2.17.4(b)        Certain Provisions Controlled by this Agreement..................... 35
                           2.17.4(c)        Continuing Warranty Under Account Agreements........................ 36
                  2.17.5   Implied Representations Upon Request for Swingline
                           Loan................................................................................. 36
                  2.17.6   Advance Not Waiver................................................................... 36

</TABLE>



                                       ii

<PAGE>   73



<TABLE>
<CAPTION>

<S>               <C>                                                                                            <C>
                  2.17.7   Interest............................................................................. 36
                           2.17.7(a) Rate of Interest........................................................... 36
                           2.17.7(b) Calculation of Interest.................................................... 36
                           2.17.7(c) Payment of Interest........................................................ 36
                           2.17.7(d) Default Rate............................................................... 36
                           2.17.7(e) Usury Savings Provision.................................................... 36
                  2.17.8   Repayment of Principal............................................................... 37
                  2.17.9   Procedures Among Lenders Upon Event of Default....................................... 37
         2.18     Withholding Tax Exemption..................................................................... 37

III.  CONDITIONS PRECEDENT...................................................................................... 38

         3.1 Conditions to Initial Advance...................................................................... 38
                  3.1.1    Credit Documents..................................................................... 38
                           3.1.1(a) Credit Agreement............................................................ 38
                           3.1.1(b) Notes....................................................................... 38
                           3.1.1(c) Security Agreements......................................................... 38
                           3.1.1(d) Pledge of Equity Interests in Subsidiaries.................................. 38
                           3.1.1(e) Charters.................................................................... 38
                           3.1.1(f) Bylaws...................................................................... 38
                           3.1.1(g) Certificates of Good Standing............................................... 38
                           3.1.1(h) Foreign Qualification....................................................... 39
                           3.1.1(i) Resolutions................................................................. 39
                           3.1.1(j) Opinions of Borrowers' Counsel.............................................. 39
                           3.1.1(k) UCC Searches................................................................ 39
                           3.1.1(l) Closing Statement and Funding of Expenses................................... 39
                           3.1.1(m) Interest Rate Protection.................................................... 39
                           3.1.1(n) Other Documents............................................................. 39
                           3.1.1(o) Landlord Consents........................................................... 39
                           3.1.1(p) Completion of Exhibits and Schedules........................................ 39
                  3.1.2    Additional Conditions................................................................ 39
                           3.1.2(a) Warranties.................................................................. 39
                           3.1.2(b) Covenants................................................................... 39
                           3.1.2(c) Absence of Unmatured Default................................................ 39
                           3.1.2(d) No Adverse Change........................................................... 40
                           3.1.2(e) Regulatory Diligence........................................................ 40
                           3.1.2(f) Ownership Structure......................................................... 40
                           3.1.2(g) Projections................................................................. 40
         3.2      Conditions to Subsequent Loans................................................................ 40
                  3.2.1    Conditions to Initial Advance........................................................ 40
                  3.2.2    Warranties........................................................................... 40
                  3.2.3    Covenants............................................................................ 40
                  3.2.4    Absence of Unmatured Default......................................................... 40
                  3.2.5    Material Adverse Change.............................................................. 40
         3.3      Participating Entity.......................................................................... 40
         3.4      Conditions Subsequent......................................................................... 41
                  3.4.1    Agreement to Pledge.................................................................. 41
                  3.4.2    Lockboxes............................................................................ 41
                  3.4.3    Landlord Consents.................................................................... 41
                  3.4.4    UCC-1 Financing Statements........................................................... 41
</TABLE>



                                       iii

<PAGE>   74
<TABLE>
<CAPTION>




<S>                                                                                                              <C>
IV.  REPRESENTATIONS AND WARRANTIES............................................................................. 41

         4.1      Capacity...................................................................................... 41
         4.2      Authorization................................................................................. 42
         4.3      Binding Obligations........................................................................... 42
         4.4      No Conflicting Law or Agreement............................................................... 42
         4.5      No Consent Required........................................................................... 42
         4.6      Financial Statements.......................................................................... 42
         4.7      Fiscal Year................................................................................... 42
         4.8      Litigation.................................................................................... 42
         4.9      Taxes: Governmental Charges................................................................... 43
         4.10     Title to Properties........................................................................... 43
         4.11     No Default.................................................................................... 43
         4.12     Casualties: Taking of Properties.............................................................. 43
         4.13     Compliance with Laws.......................................................................... 43
         4.14     Compliance with Fraud and Abuse Laws.......................................................... 44
         4.15     ERISA......................................................................................... 44
         4.16     Full Disclosure of Material Facts............................................................. 44
         4.17     Accuracy of Projections....................................................................... 45
         4.18     Investment Company Act........................................................................ 45
         4.19     Personal Holding Company...................................................................... 45
         4.20     Solvency...................................................................................... 45
         4.21     Chief Executive Office........................................................................ 45
         4.22     Subsidiaries.................................................................................. 45
         4.23     Ownership of Patents, Licenses, Etc........................................................... 45
         4.24     Environmental Compliance...................................................................... 45
         4.25     Labor Matters................................................................................. 46
         4.26     OSHA Compliance............................................................................... 46
         4.27     Regulation U.................................................................................. 46
         4.28     Affiliate Transactions........................................................................ 46
         4.29     Year 2000 Compatibility....................................................................... 46

V.  AFFIRMATIVE COVENANTS....................................................................................... 46

         5.1      Payment of Obligations........................................................................ 46
         5.2      Maintenance of Existence and Business......................................................... 46
         5.3      Financial Statements and Reports.............................................................. 47
                  5.3.1    Monthly Financial Reports............................................................ 47
                  5.3.2    Quarterly Financial Reports.......................................................... 47
                  5.3.3    Annual Financial Reports............................................................. 47
                  5.3.4    Owner Mailings....................................................................... 48
                  5.3.5    Accountant Reports................................................................... 48
                  5.3.6    Acquisition Certification............................................................ 48
                  5.3.7    Other Information.................................................................... 48
         5.4      Additional Information........................................................................ 48
         5.5      Certain Additional Reporting Requirements..................................................... 48
                  5.5.1    SEC Filings.......................................................................... 48
                  5.5.2    Change in Accounting Policies........................................................ 48
                  5.5.3    Notice to Agent Upon Perceived Breach................................................ 48
                  5.5.4    Changes in Constituent Documents..................................................... 49
                  5.5.5    Notice of Litigation................................................................. 49
</TABLE>



                                       iv

<PAGE>   75

<TABLE>
<CAPTION>



<S>               <C>                                                                                            <C>
                  5.5.6    Other Notices........................................................................ 49
         5.6      Taxes and Other Encumbrances.................................................................. 49
         5.7      Payment of Liabilities........................................................................ 49
         5.8      Compliance with Laws.......................................................................... 49
         5.9      Maintenance of Property....................................................................... 50
         5.10     Compliance with Contractual Obligations....................................................... 50
         5.11     Further Assurances............................................................................ 50
         5.12     Security Interest: Setoff..................................................................... 50
         5.13     Insurance..................................................................................... 51
                  5.13.1   General Insurance Requirements....................................................... 51
                  5.13.2   Practice-Related Insurance Requirements.............................................. 51
         5.14     Accounts and Records.......................................................................... 51
         5.15     Official Records.............................................................................. 51
         5.16     Banking Relationships......................................................................... 51
         5.17     Right of Inspection........................................................................... 51
         5.18     ERISA Information and Compliance.............................................................. 52
         5.19     Indemnity: Expenses........................................................................... 52
                  5.19.1   Taxes................................................................................ 52
                  5.19.2   Administration....................................................................... 52
                  5.19.3   Protection of Collateral............................................................. 52
                  5.19.4   Costs of Collection.................................................................. 52
                  5.19.5   Litigation........................................................................... 52
                  5.19.6   Attorneys' Fees...................................................................... 53
         5.20     Assistance in Litigation...................................................................... 53
         5.21     Name Changes.................................................................................. 53
         5.22     Estoppel Letters.............................................................................. 53
         5.23     Environmental Matters......................................................................... 53
                  5.23.1   Compliance With Environmental Laws................................................... 53
                  5.23.2   Remedial Work........................................................................ 53
                  5.23.3   Indemnification of Lenders and Agent................................................. 54
         5.24     Opinions of Counsel........................................................................... 54
         5.25     Creation or Acquisition of Subsidiaries....................................................... 54
         5.26     Existing Capital Structure of Borrower........................................................ 54
         5.27     Year 2000 Compatibility....................................................................... 55

VI.  NEGATIVE COVENANTS......................................................................................... 55

         6.1 Debts, Guaranties, and Other Obligations........................................................... 55
                  6.1.1    Obligations to Lenders............................................................... 55
                  6.1.2    Existing Liabilities................................................................. 55
                  6.1.3    Endorsements......................................................................... 55
                  6.1.4    Trade Liabilities.................................................................... 55
                  6.1.5    Taxes................................................................................ 55
                  6.1.6    Seller Debt.......................................................................... 55
                  6.1.7    Purchase Money Debt.................................................................. 55
                  6.1.8    Accounting Accruals.................................................................. 55
                  6.1.9    Liabilities Among Consolidated Entities.............................................. 56
         6.2      Change of Management.......................................................................... 56
         6.3      Change of Ownership........................................................................... 56
         6.4      Distributions................................................................................. 56
         6.5      Encumbrances.................................................................................. 56
</TABLE>




                                        v

<PAGE>   76


<TABLE>
<CAPTION>



<S>      <C>                                                                                                     <C>
         6.6      Investments................................................................................... 56
         6.7      Sales and Leasebacks.......................................................................... 57
         6.8      Change of Control............................................................................. 57
         6.9      Nature of Business............................................................................ 57
         6.10     Further Acquisitions, Mergers, Etc............................................................ 57
         6.11     Advances...................................................................................... 57
         6.12     Disposition of Assets......................................................................... 57
         6.13     Inconsistent Agreements....................................................................... 57
         6.14     Fictitious Names.............................................................................. 57
         6.15     Subsidiaries and Affiliates................................................................... 57
         6.16     Place of Business............................................................................. 57
         6.17     Adverse Action With Respect to Plans.......................................................... 58
         6.18     Transactions With Affiliates.................................................................. 58
         6.19     Constituent Document Amendments............................................................... 58
         6.20     Adverse Transactions.......................................................................... 58
         6.21     Margin Securities............................................................................. 58
         6.22     Accounting Changes............................................................................ 58
         6.23     Action Outside Ordinary Course................................................................ 58
         6.24     Modification of Subordinated Debt Documents................................................... 58

VII.  FINANCIAL COVENANTS....................................................................................... 58

         7.1      Total Funded Debt to Capital.................................................................. 58
         7.2      Total Funded Debt to Consolidated EBITDA...................................................... 59
         7.3      Fixed Charge Coverage......................................................................... 59
         7.4      Net Worth..................................................................................... 59
         7.5      Capital Expenditures.......................................................................... 59
         7.6      Outstanding Accounts.......................................................................... 59

VIII.  EVENTS OF DEFAULT........................................................................................ 59

         8.1      Events of Default............................................................................. 59
                  8.1.1  Payments............................................................................... 59
                  8.1.2  Representations and Warranties......................................................... 59
                  8.1.3  Negative Covenants..................................................................... 59
                  8.1.4  Financial Covenants.................................................................... 60
                  8.1.5  Reporting Requirements................................................................. 60
                  8.1.6  Other Covenants........................................................................ 60
                  8.1.7  Involuntary Bankruptcy or Receivership Proceedings..................................... 60
                  8.1.8  Voluntary Petitions.................................................................... 60
                  8.1.9  Discontinuance of Business............................................................. 60
                  8.1.10  Default on Other Liabilities.......................................................... 61
                  8.1.11  Undischarged Judgments................................................................ 61
                  8.1.12  Insolvency............................................................................ 61
                  8.1.13  Attachment............................................................................ 61
                  8.1.14  Insurance............................................................................. 61
                  8.1.15  Contest............................................................................... 61
                  8.1.16  Fraud and Abuse Laws.................................................................. 61
         8.2      Remedies...................................................................................... 61
                  8.2.1    Default Rate......................................................................... 61
                  8.2.2    Termination of Commitments........................................................... 61

</TABLE>


                                       vi

<PAGE>   77



<TABLE>
<CAPTION>

<S>               <C>                                                                                            <C>
                  8.2.3    Acceleration......................................................................... 62
                  8.2.4    Setoff............................................................................... 62
                  8.2.5    Other Remedies....................................................................... 62
                  8.2.6    Attorney-in-Fact..................................................................... 62
                  8.2.7    Letters of Credit.................................................................... 62

IX.  AGENT...................................................................................................... 62

         9.1      Appointment of Agent.......................................................................... 62
         9.2      Powers of Agent............................................................................... 62
                  9.2.1    Administration of Loans.............................................................. 62
                  9.2.2    Matters Reserved to Required Lenders................................................. 63
                  9.2.3    Matters Reserved to all Lenders...................................................... 63
         9.3      Duties of Agent............................................................................... 63
                  9.3.1    Specific Duties of Agent: Standard of Care........................................... 63
                  9.3.2    Limitations on Agent's Duties........................................................ 63
                  9.3.3    Agent's Right to Require Instructions in Performance of Duties....................... 64
                  9.3.4    Agent's Reliance on Others in Performance of Duties.................................. 64
                  9.3.5    Sharing of Information............................................................... 64
         9.4      Indemnification of Agent...................................................................... 64
         9.5      No Representations by Agent................................................................... 65
         9.6      Independent Investigations by Lenders......................................................... 65
         9.7      Notice of Default............................................................................. 65
         9.8      Funding of Loans Pursuant to Borrowing Notices................................................ 66
         9.9      Agent in its Individual Capacity.............................................................. 66
         9.10     Holders....................................................................................... 66
         9.11     Successor Agent............................................................................... 66
         9.12     Sharing of Payments. etc...................................................................... 67
         9.13     Separate Liens on Collateral.................................................................. 67
         9.14     Payments Between Agent and Lenders............................................................ 67
         9.15     Assignment Approvals.......................................................................... 67
         9.16     Bankruptcy Provisions......................................................................... 67
         9.17     Foreclosure of Collateral..................................................................... 68
         9.18     Procedures for Notices and Approvals.......................................................... 68
         9.19     Amendments to Article IX...................................................................... 68

X.  GENERAL PROVISIONS.......................................................................................... 68

         10.1     Notices....................................................................................... 68
         10.2     Renewal, Extension, or Rearrangement.......................................................... 69
         10.3     Application of Payments....................................................................... 69
         10.4     Counterparts.................................................................................. 69
         10.5     Negotiated Document........................................................................... 70
         10.6     Consent to Jurisdiction: Exclusive Venue...................................................... 70
         10.7     Not Partners: No Third Party Beneficiaries.................................................... 70
         10.8     No Reliance on Lenders' Analysis.............................................................. 70
         10.9     No Marshaling of Assets....................................................................... 70
         10.10    Impairment of Collateral...................................................................... 70
         10.11    Business Days................................................................................. 70
         10.12    Participations and Assignments................................................................ 71
         10.13    Standard of Care: Limitation of Damages....................................................... 72
</TABLE>



                                       vii

<PAGE>   78

<TABLE>
<CAPTION>



<S>      <C>                                                                                                     <C>
         10.14    Incorporation of Schedules.................................................................... 72
         10.15    Indulgence Not Waiver......................................................................... 72
         10.16    Cumulative Remedies........................................................................... 72
         10.17    Amendment and Waiver in Writing............................................................... 72
         10.18    Assignment.................................................................................... 72
         10.19    Entire Agreement.............................................................................. 73
         10.20    Severability.................................................................................. 73
         10.21    Time of Essence............................................................................... 73
         10.22    Applicable Law................................................................................ 73
         10.23    Captions Not Controlling...................................................................... 73
         10.24    Arbitration................................................................................... 73
                  10.24.1           Special Rules............................................................... 73
                  10.24.2           Reservation of Rights....................................................... 74
         10.25    Facsimile Signatures.......................................................................... 74
         10.26    Obligations Absolute.......................................................................... 74
         10.27    Termination................................................................................... 74

EXHIBITS

         Exhibit 1.2 - Acquisition Certificate
         Exhibit 1.3.6 - Assumption Agreement
         Exhibit 2.5.1(b) - Borrowing/Conversion Notice
         Exhibit 10.12 - Form of Assignment and Acceptance

SCHEDULES

         Schedule 3.1.1(d) - Subsidiaries
         Schedule 3.1.1(o) - Landlord Waivers for Closing
         Schedule 3.4.1 - Impact Centers - Hospital Joint Ventures
         Schedule 3.4.3 - Subsequent Landlord Waivers
         Schedule 4.1 - Corporate Structure
         Schedule 4.8 - Litigation
         Schedule 4.9 - Tax Extensions
         Schedule 4.28 - Affiliate Transactions
         Schedule 5.26 - Description of Current Ownership Structure
         Schedule 6.1.2 - Existing Liabilities
         Schedule 6.1.6 - Subordinated Debt
         Schedule 6.2 - Management Staffing
</TABLE>




                                      viii

<PAGE>   1
                                                                    Exhibit 10.b

     233 South Wacker Drive, Suite 2800
     Chicago, Illinois 60606
     Tel 312-234-2732
     Fax 312-234-3160

NationsBank

TO:    Response Oncology, Inc.
       1775 Moriah Woods Blvd.
       Memphis, TN 38117

ATTN:  Mary Clements
PHONE: 901-761-7000
FAX:   901-763-7045

FROM:  NationsBank, N.A.
       233 South Wacker Drive - Suite 2800
       Chicago, Illinois 60606
       Mike Allison/John Dewaschinski

Date:  25JUN99

Our Reference No. 912138  1039973

     The purpose of this letter agreement is to confirm the terms and
conditions of the Transaction entered into between us on the Trade Date
specified below (the "Transaction"). This letter agreement constitutes a
"Confirmation" as referred to in the ISDA Master Agreement specified below in
paragraph 1 (the "Agreement").

     The definitions and provisions contained in the 1991 ISDA Definitions (as
published by the International Swaps and Derivatives Association, Inc.
(formerly known as the International Swap Dealers Association, Inc.) ("ISDA")
(the "Definitions")) are Incorporated into this Confirmation. In the event of
any inconsistency between the Definitions and this Confirmation, this
Confirmation will govern. Without prejudice to the preceding sentence,
references in this Confirmation to the Transaction shall for the purposes of
the Definitions mean the Swap Transaction.

     1. This Confirmation supplements, forms part of, and is subject to, the
ISDA Master Agreement dated as of May 12, 1997, as amended and supplemented
from time to time (the "Agreement"), between you and us. All provisions
contained in the Agreement govern this Confirmation except as expressly
modified below,

     In this Confirmation "Party A" means NationsBank, N.A., and "Party B"
means Response Oncology, Inc.

     2. The terms of this Swap Transaction to which this Confirmation relates
are as follows:

     Trade Date:          24JUN99
     Effective Date:      01JUL99
     Termination Date:    01JUL00 subject to adjustment in accordance with the
                          Modified Following Business Day Convention


Fixed Amounts:

     Fixed Rate Payer:    Party B

     Fixed Rate Payer
     Currency Amount:     USD 18,000,000.00

     Fixed Rate Payer
     Payment Dates:       The 1st of each January, April, July and October,
                          commencing 01OCT99 and ending 01JUL00, subject to
                          adjustment in accordance with the Modified Following
                          Business Day Convention.

     Business Days:       New York, London

     Fixed Rate:          5.93000%


<PAGE>   2
     Fixed Rate Day
     Count Fraction:         Actual/360

Floating Amounts:

     Floating Rate Payer:    Party A

     Floating Rate Payer
     Currency Amount:        USD 18,000,000.00

     Floating Rate Payer
     Payment Dates:          The 1st of each January, April, July and October,
                             commencing 01OCT99 and ending 01JUL00, subject to
                             adjustment in accordance with the Modified
                             Following Business Day Convention.

     Business Days:          New York, London

     Floating Rate for
     Initial Calculation
     Period:                 TO BE SET

     Floating Rate Option:   USD-LIBOR-BBA

     Designated Maturity:    3 Month

     Spread:                 None

     Floating Rate Day
     Count Fraction:         Actual/360

     Reset Dates:            The first day of each Calculation Period

     Averaging:              Inapplicable

     Compounding:            Inapplicable

     Calculation Agent:      NationsBank, N.A.

3.   Recording of
     Conversations:          Each party to this Agreement acknowledges and
                             agrees to the tape or electronic recording of
                             conversations between the parties to this
                             Agreement whether by one or other or both of the
                             parties, and that any such recordings may be
                             submitted in evidence in any action or proceeding
                             relating to the Agreement or any Transaction.

4.   Account Details:

     Payments to NationsBank, N.A.:
                  USD
We will debit your account,
     NAME:     NATIONSBANK TN
     ABA #:    064000020
     ACCT:
          RESPONSE ONCOLOGY




<PAGE>   3
     Payment to Response Oncology, Inc.
               USD
     NAME:     NATIONSBANK TN
     CITY:     NASHVILLE
     ABA #:    064000020
     ATTN:     NABKUS3ANAS
     NAME:     RESPONSE ONCOLOGY
     ACCT:


5. Offices:
     The Office of NationsBank, N.A. for this Swap Transaction is: Charlotte, NC

     The Office of Response Oncology, Inc. for this Swap Transaction is:
     Tennessee, USA


   Credit Support Document: As per Agreement (and Credit Support Annex
if applicable).


     Please confirm that the foregoing correctly sets forth the terms and
conditions of our agreement by responding within three (3) Business Days by
returning via telecopier an executed copy of this Confirmation to the attention
of Swaps Documentation Group at Fax No. (312) 234-2543 or (312) 234-3160.
Failure to respond within such period shall not affect the validity or
enforceability of this Swap Transaction, and shall be deemed to be an
affirmation of the terms and conditions contained herein, absent manifest error.


Yours Sincerely,

NationsBank, N.A.

By /s/ Louis B. Conrad
   ----------------------
   Senior Vice President

Authorized Signatory

Accepted and confirmed as of the date first written:

Response Oncology, Inc.

By /s/ Mary E. Clements
   --------------------

Name:  Mary E. Clements
       ----------------

Title: Chief Financial Officer
       -----------------------

Our Reference # 912138



<TABLE> <S> <C>

<ARTICLE> 5
<MULTIPLIER> 1,000

<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-START>                             JAN-01-1999
<PERIOD-END>                               JUN-30-1999
<CASH>                                           3,948
<SECURITIES>                                         0
<RECEIVABLES>                                   23,196
<ALLOWANCES>                                     2,609
<INVENTORY>                                      3,069
<CURRENT-ASSETS>                                50,174
<PP&E>                                          16,148
<DEPRECIATION>                                  11,610
<TOTAL-ASSETS>                                 122,782
<CURRENT-LIABILITIES>                           27,978
<BONDS>                                         35,884
                                0
                                         27
<COMMON>                                           119
<OTHER-SE>                                      50,524
<TOTAL-LIABILITY-AND-EQUITY>                   122,782
<SALES>                                         34,053
<TOTAL-REVENUES>                                70,362
<CGS>                                           40,243
<TOTAL-COSTS>                                   67,376
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                                   695
<INTEREST-EXPENSE>                               1,706
<INCOME-PRETAX>                                  2,600
<INCOME-TAX>                                       988
<INCOME-CONTINUING>                              1,612
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     1,612
<EPS-BASIC>                                       0.13
<EPS-DILUTED>                                     0.13


</TABLE>


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission