CAPSTEAD MORTGAGE CORP
SC 13G/A, 1995-02-14
REAL ESTATE INVESTMENT TRUSTS
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                     SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C.  20549

                                SCHEDULE 13G

                 Under the Securities Exchange Act of 1934
                             (Amendment No. 4)*

                         Capstead Mortgage Corporation                
                              (Name of Issuer)

                   Common Stock, par value $0.01 per share            
                       (Title of Class and Securities)

                                  14067E 10 0                         
                   (CUSIP Number of Class of Securities)

     No fee is required with respect to this filing.

     *The remainder of this cover page shall be filled out for
     reporting person's initial filing on this form with respect to
     the subject class of securities, and for any subsequent amendment
     containing information which would alter the disclosures provided
     in a prior cover page.

     The information required in the remainder of this cover page
     shall be deemed to be "filed" for the purpose of Section 18 of
     the Securities Exchange Act of 1934 ("Act") or otherwise subject
     to the liabilities of that section of the Act but shall be
     subject to all other provisions of the Act (however, see the
     Notes).


                                SCHEDULE 13G

     CUSIP No. 14067E 10
            
                     
     (1)  NAMES OF REPORTING PERSONS
          S.S. OR I.R.S. IDENTIFICATION
     NOS. OF ABOVE PERSONS

     Howard Hughes Medical Institute                                  

     I.R.S. Indemnification No.:  59-0735717                          

     (2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP:
                                                            
                                                               (a)  ( )
                                                                
                                                               (b)  ( )
     Not applicable                                                   

     (3)  SEC USE ONLY
                                                                      

     (4)  CITIZENSHIP OR PLACE OF ORGANIZATION 

     Delaware                                                         

                              (5)  SOLE VOTING POWER

                                   1,175,780(includes, pursuant to 
                                   Rule 13d-3(d)(1)(i)(B), 175,780
                                   shares that would be received upon
                                   conversion of 550,000 shares of
                                   issuer's series B convertible
                                   preferred stock held by the
                                   Institute)
         NUMBER                                                    
           OF                 (6)  SHARED VOTING POWER
         SHARES
      BENEFICIALLY                 0                               
        OWNED BY              (7)  SOLE DISPOSITIVE POWER
          EACH
       REPORTING                   1,175,780 (includes, pursuant to
      PERSON WITH                  Rule 13d-3(d)(1)(i)(B), 175,780
                                   shares that would be received upon
                                   conversion of 550,000 shares of
                                   issuer's series B convertible
                                   preferred stock held by the
                                   Institute)
                                                          
                              (8)  SHARED DISPOSITIVE POWER

                                   0                                  


     (9)  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,175,780 (includes, pursuant to Rule 13d-3(d)(1)(i)(B), 175,780
     shares that would be received upon conversion of 550,000 shares
     of issuer's series B convertible preferred stock held by the
     Institute)                                                       

     (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN
          SHARES*                                                  (  )

     (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     7.6% (includes, pursuant to Rule 13d-3(d)(1)(i)(B), 175,780
     shares that would be received upon conversion of 550,000 shares
     of issuer's series B convertible preferred stock held by the
     Institute)                                                       

     (12) TYPE OF REPORTING PERSON*

     EP                                                               


     Item 1.

          (a)  Name of Issuer:  Capstead Mortgage Corporation ("CMC").
          (b)  Address of Issuer's Principal Executive Offices:  2711
               North Haskell, Dallas, Texas 75204

     Item 2.

          (a)  Name of Person Filing:  Howard Hughes Medical Institute.
          (b)  Address of Principal Business Office:  4000 Jones
               Bridge Road, Chevy Chase, Maryland 20815-6789.
          (c)  Citizenship:  Delaware corporation.
          (d)  Title of Class of Securities:  Common Stock, par value
               $0.01 per share, of CMC.
          (e)  CUSIP Number:  14067E 10 0.

     Item 3.   If this statement is being filed pursuant to Rule 13d-
     1(b) or 13d-2(b), check whether the person filing is:  

     [X] Employee Benefit Plan, Pension Fund which is subject to the
     provisions of the Employee Retirement Income Security Act of 1974
     or Endowment Fund.

     Item 4.   Ownership.

          (a)  Amount beneficially Owned:  1,175,780, which includes,
               pursuant to Rule 13d-3(d)(1)(i)(B), 175,780 shares that
               would be received upon conversion of 550,000 shares of
               issuer's series B convertible preferred stock held by
               the Institute.
          (b)  Percent of Class:  7.6%
          (c)  Number of shares as to which such person has:
               (i)  Sole power to vote or to direct the vote: 
                    1,175,780 (see item 4(a), above).
               (ii) Shared power to vote or to direct the vote:  0.
               (iii)Sole power to dispose or to direct the
                    disposition:  1,175,780 (see item 4(a), above).
               (iv) Shared power to dispose or to direct the
                    disposition:  0.

     Item 5.   Ownership of Five Percent or Less of a Class:  N/A.

     Item 6.   Ownership of More than Five Percent on Behalf of
               Another Person:  N/A.

     Item 7.   Identification and Classification of the Subsidiary
               Which Acquired the Security Being Reported on By the
               Parent Holding Company:  N/A.

     Item 8.   Identification and Classification of Members of the
               Group:  N/A.

     Item 9.   Notice of Dissolution of Group:  N/A.

     Item 10.  Certification.

          By signing below I certify that, to the best of my knowledge
     and belief, the securities referred to above were acquired in the
     ordinary course of business and were not acquired for the purpose
     of and do not have the effect of changing or influencing the
     control of the issuer of such securities and were not acquired in
     connection with or as a participant in any transaction having
     such purposes or effect.

     SIGNATURE

          After reasonable inquiry and to the best of my knowledge and
     belief, I certify that the information set forth in this
     statement is true, complete and correct.

     Dated:  February 14, 1995

     HOWARD HUGHES MEDICAL INSTITUTE

     By:  \s\ Craig A. Alexander
          Craig A. Alexander, Esq.
          Deputy General Counsel



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