MEDICAL ADVISORY SYSTEMS INC
SC 13D, 2000-03-31
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<PAGE>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13D


                    Under the Securities Exchange Act of 1934


                         MEDICAL ADVISORY SYSTEMS, INC.
                       -----------------------------------
                                (Name of Issuer)


                     Common Stock, $.005 par value per share
                     ---------------------------------------
                         (Title of Class of Securities)

                                   58449P 10 1
                                 --------------
                                 (CUSIP Number)

                            John W. Kauffman, Esquire
                          Duane, Morris & Heckscher LLP
                             4200 One Liberty Place
                      Philadelphia, Pennsylvania 19103-7396
                                 (215) 979-1227
    -----------------------------------------------------------------------
            (Name, Address and Telephone Number of Person Authorized
                     to Receive Notices and Communications)


                                 March 21, 2000
                     ---------------------------------------
             (Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box
|_|.

Note: Schedules filed in paper format shall include a signed original and five
copies of the Schedule, including all exhibits. See Rule 13d-7(b) for other
parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

CUSIP No.  58449P 10 1
<PAGE>
_______________________________________________________________________________

CUSIP No.  58449P 10 1                                      Page 2 of 6 Pages
_______________________________________________________________________________

    1      NAME OF REPORTING PERSONS
           S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (Entities Only)

           Premier Research Worldwide, Ltd.
______________________________________________________________________________

    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP  (see Instructions)
                                                                   (a)  [ ]
                                                                   (b)  [X]
______________________________________________________________________________

    3      SEC USE ONLY
______________________________________________________________________________

    4      SOURCE OF FUNDS (See Instructions)
             WC
______________________________________________________________________________

    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
           PURSUANT TO ITEMS 2(d) OR 2(e)                            [ ]
______________________________________________________________________________

    6      CITIZENSHIP OR PLACE OF ORGANIZATION
             State of Delaware
_______________________________________________________________________________
               |     |
  NUMBER OF    |  7  |   SOLE VOTING POWER
   SHARES      |     |     550,000 shares
BENEFICIALLY   |_____|________________________________________________________
  OWNED BY     |     |
   EACH        |  8  |   SHARED VOTING POWER
 REPORTING     |     |     None
  PERSON       |_____|________________________________________________________
   WITH        |     |
               |  9  |   SOLE DISPOSITIVE POWER
               |     |     550,000
               |_____|________________________________________________________
               |     |
               | 10  |   SHARED DISPOSITIVE POWER
               |     |     None
_______________|_____|_________________________________________________________

   11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
            550,000 shares
______________________________________________________________________________

   12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES (See Instructions)
______________________________________________________________________________

   13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
            10.9%
______________________________________________________________________________

   14     TYPE OF REPORTING PERSON (See Instructions)
            CO
______________________________________________________________________________

<PAGE>



CUSIP No.  58449P 10 1                                         Page 3 of 6 Pages

Item 1. Security and Issuer.

         This Schedule 13D constitutes the initial filing by Premier Research
Worldwide, Ltd. (the "Reporting Person") relating to the ownership by the
Reporting Person of the common stock, par value $.005 per share, of Medical
Advisory Systems, Inc. (the "Issuer"). The address of the Issuer's principal
executive office is 8050 Southern Maryland Boulevard, Owings, Maryland 20736.

Item 2. Identity and Background.

         The Reporting Person is a company organized and existing under the laws
of Delaware, the principal offices of which are located at 30 S. 17th Street,
Philadelphia, Pennsylvania 19103. The Reporting Person's principal business is
as an e-research technology and service provider.

         Certain information concerning the directors and executive officers of
the Reporting Persons is set forth below:

         Joel Morganroth, MD is the Chairman and Chief Executive Officer of the
Reporting Person, Adjunct Professor of Medicine at Jefferson Medical College of
Thomas Jefferson University and Clinical Professor of Medicine at the University
of Pennsylvania School of Medicine. His business address is 30 S. 17th Street,
Philadelphia, Pennsylvania 19103 and he is a United States citizen.

         Joseph Esposito is the President, Chief Operating Officer and Director
of the Reporting Person. His business address is 30 S. 17th Street,
Philadelphia, Pennsylvania 19103 and he is a United States citizen.

         John Ryan is a director of the Reporting Person and is a principal in
Devon Ventures, an investment firm. His business address is 102 Minford Drive,
Bala Cynwyd, Pennsylvania 19004 and his is a United States citizen.

         Sheldon Bonovitz is a director of the Reporting Person and is a
partner, Chairman and Chief Executive Officer of the law firm of Duane, Morris &
Heckscher, LLP. His business address is 4200 One Liberty Place, Philadelphia,
Pennsylvania 19103 and he is a United States citizen.

         James Gale is a director of the Reporting Person and is a managing
director of Sanders Morris Mundy, a registered broker dealer and is the Chief
Investment Officer of the Corporate Opportunity Funds which are limited
partnerships whose principal business is making investments in the securities of
other entities. His business address is 3100 Chase Tower, Houston, Texas 77002
and he is a United States citizen.
<PAGE>

CUSIP No.  58449P 10 1                                         Page 4 of 6 Pages

         Arthur Hull Hayes, Jr., M.D. is a director of the Reporting Person and
is the President and Chief Operating Officer of MediScience Associates, a
consulting firm. His business address is 71 Elk Road, New Rochelle, New York
10804 and he is a United States citizen.

         Jerry D. Lee is a director of the Reporting Person and was a partner in
the accounting firm of Ernst & Young LLP until his retirement in 1995. His
business address is Golf Club Road, Greenwich, Connecticut 06830 and he is a
United States citizen.

         Howard Ross is a director of the Reporting Person and is a partner of
LLR Equity Partners, L.P. His business address is 1150 First Avenue, Suite 100,
King of Prussia, Pennsyl vania 19406 and he is a United States citizen.

         Philip J. Whitcome is a director of the Reporting Person and is
Chairman of the Board of Directors of Avigen, a biotechnology company. His
business address is 99 Field Brook Road, Madison, Connecticut 06443 and he is a
United States citizen.

         Connie Woodburn is a director of the Reporting Person and is Executive
Vice President for Corporate Sales of Cardinal Health, Inc., a national drug
wholesaler. Her business address is 7000 Cardinal Place, Dublin, Ohio 43017 and
she is a United States citizen.

         Vincent Renz is the Senior Vice President, Technology and Consulting of
the Report ing Person. His business address is 30 S. 17th Street, Philadelphia,
Pennsylvania 19103 and he is a United States citizen.

         Robert Brown is the Senior Vice President, Core Diagnostics of the
Reporting Person. His business address is 30 S. 17th Street, Philadelphia,
Pennsylvania 19103 and he is a United States citizen.

         John Bauer is Vice President and Chief Financial Officer of the
Reporting Person. His business address is 30 S. 17th Street, Philadelphia,
Pennsylvania 19103 and he is a United States citizen.

         Bruce Johnson is Senior Vice President and Chief Financial Officer of
eResearchTechnology, Inc., a subsidiary of the Registrant. His business address
is 30 S. 17th Street, Philadelphia, Pennsylvania 19103 and he is a United States
citizen.

         During the last five years, none of the foregoing persons has been
convicted in a criminal proceeding or was a party to a civil proceeding of a
judicial or administrative body of competent jurisdiction, which resulted in or
made any of them subject to any judgment, decree or final order enjoining future
violations of, or prohibiting or mandating activities subject to, federal or
state securities laws or finding any violation with respect to such laws.
<PAGE>

CUSIP No.  58449P 10 1                                         Page 5 of 6 Pages

Item 3. Source and Amount of Funds or Other Consideration.

         The Reporting Person acquired the Shares pursuant to a Stock Purchase
Agreement dated March 8, 2000 between the Reporting Person and the Issuer (the
"Purchase Agreement") whereby the Reporting person acquired 550,000 shares of
Common Stock of the Issuer for an aggregate price of $5,775,500, which
transaction was consummated on March 21, 2000. The purchase price was drawn from
working capital of the Reporting Person.

Item 4. Purpose of Transaction.

         The Reporting Person is acquiring the shares of the Issuer for
investment. Other than as described above, the Reporting Person does not have
any plans or proposals that relate to or would result in any of the actions
described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

Item 5. Interest in Securities of Issuer.

         (a) The Reporting Person beneficially owns 550,000 Shares, or
approximately 10.9%, of the outstanding shares of Common Stock of the Issuer. No
other person named in Item 2 beneficially owns shares of Common Stock of the
Issuer.

         (b) The Reporting Person has the sole power to vote or to direct the
vote, and sole power to dispose or direct the disposition, of the Shares.

         (c) The Reporting Person has not entered into any other transactions in
the class of securities reported on that were effected in the past sixty days.

         (d) Not applicable.

         (e) Not applicable.

Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to
        Securities of the Issuer.

         The Reporting Person and the Issuer entered into the Purchase
Agreement, a copy of which is attached as an exhibit to this Schedule 13D
report. Section 3 of the Purchase Agreement provides a first refusal right for
the Reporting Person. Under this provision, in the event that a third party or
group seeks to acquire the Issuer or substantially all of the Issuer's business
or assets by tender offer, merger, asset sale, stock sale or purchase or other
business combination, which the Issuer has deemed an acceptable offer by its
board of directors, the Reporting Person shall have the right to acquire the
Issuer, or such portion, as the case may be, in accordance with the terms of
such offer and the provisions of Section 3 of the Purchase Agreement. This first
refusal right expires at the close of business on September 15, 2000.

Item 7. Materials to be filed.

         Exhibit 1: Stock Purchase Agreement dated as of March 8, 2000 between
                    the Reporting Person and the Issuer.
<PAGE>

CUSIP No.  58449P 10 1                                         Page 6 of 6 Pages


SIGNATURES:

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

                                             PREMIER RESEARCH WORLDWIDE, LTD.


Date:  March 30, 2000                        By: /s/ Joel Morganroth, M.D.
                                                 -------------------------------
                                                 Joel Morganroth, M.D., Chairman
                                                 and Chief Executive Officer
<PAGE>

                                    EXHIBIT 1

                            STOCK PURCHASE AGREEMENT


         THIS STOCK PURCHASE AGREEMENT is made as of the 8th day of March, 2000,
by and between Medical Advisory Systems, Inc. (the "Seller"), a Delaware
corporation; and Premier Research Worldwide, Ltd. (the "Buyer"), a Delaware
corporation. The Seller and the Buyer are referred to herein collectively as the
"Parties."

                                    Recitals:

         The Seller wishes to sell to the Buyer, and the Buyer wishes to
purchase from the Seller, 550,000 shares of the Seller's Common Stock, par value
$.005 (the "Common Stock"), in accordance with the terms and provisions of this
Agreement.

         The Seller's Common Stock is registered under the Securities Exchange
Act of 1934 (the "Exchange Act") and listed on the NASDAQ/AMEX.

         NOW, THEREFORE, the Parties hereto, intending to be legally bound
hereby, agree as follows:

         1. Definitions.

            "Accredited Investor" has the meaning set forth in Regulation D
promulgated under the Securities Act.

            "Adverse Consequences" means all actions, suits proceedings,
hearings, investigations, charges, complaints, claims, demands, injunctions,
judgments, orders, decrees, rulings, damages, dues, penalties, fines, costs,
amounts paid in settlement, Liabilities, obligations, Taxes, liens, losses,
expenses, and fees, including court costs and reasonable attorneys' fees and
expenses.

            "Affiliate" has the meaning set forth in Rule 12b-2 of the
regulations promulgated under the Exchange Act.

            "Audit" means any audit, assessment or other examination relating to
Taxes by any Tax Authority or any judicial or administrative proceedings
relating to Taxes.

            "COBRA" means the requirements of Part 6 of Subtitle I of ERISA and
Code Section 4980B.

            "Code" means the Internal Revenue Code of 1986, as amended.

            "Environmental Laws" shall mean all federal, state, local and
foreign statutes, regulations, ordinances and other provisions having the force
and effect of laws, all judicial and administrative orders and determinations,
all contractual obligations and all common law concerning pollution or

<PAGE>

protection of the environment, or the impact of the environment on human health,
including without limitation all those relating to the presence, use,
production, generation, handling, transportation, treatment, storage, disposal,
distribution, labeling, testing, processing, discharge, release, threatened
release, control, or cleanup of any hazardous materials, substances or wastes,
chemical substances or mixtures, pesticides, pollutants, contaminants, toxic
chemicals, petroleum products or byproducts, asbestos, polychlorinated
biphenals, noise or radiation, each as amended and as now or hereafter in
effect.

            "ERISA" means the Employee Retirement Income Security Act of 1974,
as amended.

            "eRT" means eResearch Technology, Inc., a wholly owned subsidiary of
the Buyer.

            "GAAP" means United States generally accepted accounting principles
as in effect from time to time.

            "Health and Safety Requirements" shall mean all federal, state,
local and foreign statutes, regulations, ordinances and other provisions having
the force and effect of laws, all judicial and administrative orders and
determinations, all contractual obligations and all common law concerning public
health and safety, and worker health and safety, including without limitation
all those relating to the presence, use, production, generation, handling,
transportation, treatment, storage, disposal, distribution, labeling, testing,
processing, discharge, release, threatened release, control, or cleanup of any
hazardous materials, substances or wastes, chemical substances or mixtures,
pesticides, pollutants, contaminants, toxic chemicals, petroleum products or
byproducts, asbestos, polychlorinated biphenals, noise or radiation, each as
amended and as now or hereafter in effect.

            "Knowledge" means actual knowledge.

            "Liability" means any liability (whether known or unknown, whether
asserted or unasserted, whether absolute or contingent, whether accrued or
unaccrued, whether liquidated or unliquidated, and whether future or become
due), including any liability for Taxes.

            "License Agreement" means the Master Software License Agreement
between eRT and the Seller.

            "Ordinary Course of Business" means the ordinary course of business
consistent with past custom and practice (including with respect to quantity and
frequency).

            "PBGC" means the Pension Benefit Guaranty Corporation.

            "Person" means an individual, a partnership, a corporation, an
association, a joint stock company, a trust, a joint venture, an unincorporated
organization, or a governmental entity (or any department, agency, or political
subdivision thereof).

            "SEC" means the United States Securities and Exchange Commission.

            "Securities Act" means the Securities Act of 1933, as amended.

                                       2
<PAGE>

            "Exchange Act" means the Securities Exchange Act of 1934, as
amended.

            "Security Interest" means any mortgage, pledge, lien, encumbrance,
charge or other security interest, other than (a) liens for Taxes not yet due
and payable, (b) purchase money liens and liens securing rental payments under
capital lease arrangements, and (c) other liens arising in the Ordinary Course
of Business and not incurred in connection with the borrowing of money.

            "Service Agreement" means Service, Sales and Co-Marketing Agreement
dated as of April 1, 2000 between Buyer's wholly owned subsidiary, eRT and the
Seller.

            "Tax" means any federal, state, local or foreign, income, gross
receipts, license, payroll, employment, excise, severance, stamp, occupation,
premium, windfall profits, environmental (including taxes under Code Section
59A), custom duties, capital stock, franchise, profits, withholding, social
security (or similar), unemployment, disability, real property, personal
property, sales, use, transfer, registration, value added, alternative or add-on
minimum, estimated, or other tax of any kind whatsoever, including any interest,
penalty, or addition thereto, whether disputed or not.

            "Tax Authority" means the Internal Revenue Service and any other
domestic or foreign governmental authority responsible for the administration of
any Taxes.

            "Tax Return" means any return, declaration, report, claim for
refund, or information return or statement relating to Taxes, including any
schedule or attachment thereto, and including any amendment thereof required to
be filed with any Tax Authority.

         2. Purchase and Sale; Use of Proceeds.

            (a) Number of Shares. The Seller is selling to the Buyer, and the
Buyer is purchasing from the Seller, 550,000 shares of the Seller's Common
Stock, representing, upon completion of the transaction, approximately 11.1% of
the Seller's issued and outstanding Common Stock. The shares being purchased and
sold pursuant to this Agreement are hereinafter sometimes referred to
individually as a "Share" and collectively as the "Shares."

            (b) Purchase Price. The aggregate purchase price for the Shares (the
"Purchase Price") shall be $5,775,000. The Buyer agrees to pay the Seller the
Purchase Price in cash payable by wire transfer or delivery of other immediately
available funds.

            (c) Use of Proceeds. Seller shall use the proceeds from the sale of
the Shares as follows: (i) $2,700,000 under the License Agreement; (ii) for
infrastructure agreed upon in the Service Agreement ; and (iii) the balance for
working capital and other corporate purposes.


         3. Right of First Refusal.

            (a) Grant. Commencing on the Closing Date, the Buyer, including its
assignees, and any of its majority owned subsidiaries and its assignees, is

                                       3
<PAGE>

hereby granted the right of first refusal (the "First Refusal Right") as set
forth in this Section 3. In the event that a third party or group seeks to
acquire the Seller or substantially all of Seller's business or assets by tender
offer, merger, asset sale, stock sale or purchase, or other business combination
(collectively, referred to as a "Sale Event"), which MAS has deemed an
acceptable offer (the "Sale Offer") as determined by Board of Directors of MAS,
the Buyer shall have the right to acquire the Seller, or such portion, as the
case may be, in accordance with the terms of the Sale Offer, as more fully
described in 3(c) hereof This First Refusal Right shall terminate and expire at
the close of business on September 15, 2000.

            (b) Notice of a Sale Offer. In the event of a Sale Offer, the Seller
shall promptly notify the Buyer, in writing, of the terms of the Sale Offer,
including the purchase price, the other material terms of the transaction and
the identity of the third party offeror (the "Notice of Offer"). The date that
the Buyer receives the Notice of Offer is hereafter defined as the "Notice
Date."

            (c) Exercise of First Refusal Right. Buyer shall have the First
Refusal Right with respect to a Sale Offer. Buyer shall have thirty (30)
calendar days commencing on the calendar day following receipt of Buyer of the
Notice of Offer within which to inform Seller in writing that it exercises its
First Refusal Right and will enter into the Sale Event on substantially similar
structural terms and economic conditions as set forth in the Notice of Offer. In
the event Buyer notifies Seller of its exercise of its First Refusal Right for a
Sale Event, Buyer and Seller shall cooperate in good faith in negotiating and
executing customary definitive documentation and in taking such other action as
is reasonably necessary and customary to consummate the Sale Event on the same
terms and conditions as set forth in the Notice of Offer.

            (d) Non-Exercise of the First Refusal Right. In the event (i) the
Seller does not deliver the Exercise Notice to the Seller prior to the
expiration of the 30-day exercise period Buyer's First Refusal Right shall
terminate and be of no further force and effect with respect to the Sale Event
which is the subject of the Notice of Offer, but will remain in effect with
respect to any other Sale Event, including any material modification of a Sale
Event which is the subject of a Notice of Offer with respect to which Buyer
previously elected not to exercise its First Refusal Right.

         4. Closing.

         (a) The Closing. The closing of the purchase of the Shares contemplated
by this Agreement (the "Closing") shall take place at the office of the Buyer,
on March 21, 2000, or at such other place, time and date as the Buyer and the
Seller may mutually determine (the "Closing Date").

            (b) Deliveries at the Closing. At Closing:

                (i) Seller shall deliver to the Buyer a certificate of most
recent practicable date as to the corporate good standing of Seller issued by
the Secretary of State of Delaware;

                (ii) Seller shall deliver to Buyer a certified copy of its
Articles of Incorporation and Bylaws and resolutions of its Board of Directors
authorizing and approving all matters in connection with the Agreement and the
transactions contemplated thereby;

                                       4

<PAGE>

                (iii) Seller's counsel shall deliver to Buyer an opinion in the
form and substance acceptable to the Buyer and its counsel, dated as of the
Closing Date;

                (iv) Seller and eRT shall execute and deliver the Licensing
Agreement;

                (v) Seller and eRT shall execute and deliver the Services
Agreement;

                (vi) Seller shall deliver to Buyer one certificate representing
the Shares; and

                (vii) Buyer shall deliver the consideration specified in Section
2(b) above.

         5. Representations and Warranties of the Seller. Subject to the
disclosures set forth on Seller's disclosure schedule, dated as of the date
hereof and delivered herewith ("Seller Disclosure Schedule"), Seller represents
and warrants to the Buyer as set forth in this Section 5. The inclusion of
information on Seller's Disclosure Schedule shall be deemed adequate to disclose
an exception to a representation or warranty made therein if the information
contained thereon would provide notice to a reasonable person of the existence
of a fact or circumstance which would be contrary to the substance of the
applicable representation and/or warranty. Subject to the foregoing, Seller
represents and warrants to the Buyer as follows:

            (a) Validity of Issuance. The Shares being sold by the Seller
hereunder have been duly authorized, and, upon the issuance of such Shares to
the Buyer in accordance with the terms and provisions of this Agreement, such
Shares will be validly issued, fully paid and nonassessable.

            (b) Organization, Qualification and Corporate Power. The Seller (i)
is a corporation duly organized, validly existing and in good standing under the
laws of the jurisdiction of its incorporation, (ii) has the corporate power and
authority to own its property and assets and to transact the business in which
it is engaged and (iii) is duly authorized to conduct business and is in good
standing under the laws of each jurisdiction where such qualification is
required except where any failure to be so qualified would not have a material
adverse effect either individually or in the aggregate on Seller. The Seller has
full corporate power and authority and all licenses, permits and authorizations
necessary to carry on the business in which it is engaged and to own and use the
properties owned and used by it. The Seller has delivered to the Buyer correct
and complete copies of its certificate of incorporation and bylaws. The minute
books (containing the records of meetings of the stockholders, the board of
directors and any committees of the board of directors), the stock certificate
books, and the stock record books of the Seller are complete, correct and
accurate.

            (c) Authorization, Validity and Effect. The Seller has the requisite
corporate power to execute, deliver and perform the terms and provisions of this
Agreement and has taken all necessary corporate action to authorize the
execution, delivery and performance of this Agreement by the Seller. This
Agreement constitutes, and all agreements and documents described herein (when
executed and delivered pursuant hereto for value received) will constitute, the
valid and binding obligations of Seller enforceable in accordance with their
respective terms, subject to applicable bankruptcy, insolvency, moratorium or

                                       5
<PAGE>

other similar laws relating to creditor's rights and general principles of
equity.

            (d) No Consent Required. No authorization, consent or approval of,
or exemption by, any governmental or public body or authority is required to
authorize, or is required in connection with, the execution, delivery and
performance of any of this Agreement, or the taking of any action contemplated
hereby, by the Seller, except such authorizations, consents or approvals which
the failure of Seller to obtain will not either individually or in the aggregate
have a material adverse affect on the financial condition or results of
operations of Seller.

            (e) No Defaults. No material default exists under any agreement to
which the Seller is a party or by which it is bound, which default, if not
cured, would have a material adverse effect upon the financial condition or the
results of operations of the Seller.

            (f) No Violation. Neither the execution and delivery of this
Agreement, nor compliance with any of the terms and provisions hereof, nor the
consummation of any of the transactions herein contemplated will: (i) violate
any law, statute, regulation, rule, order, writ, injunction, judgment, ruling,
charge, decree or other restriction of any court or governmental department,
commission, board, bureau, agency or instrumentality applicable to the Seller,
or (ii) conflict or be inconsistent with, or result in any breach of, any of the
terms, covenants, conditions or provisions of, or constitute a default under, or
result in the creation or imposition of (or the obligation to create or impose)
any lien, charge or encumbrance upon any of the property or assets of the Seller
pursuant to the terms of any indenture, mortgage, deed of trust, agreement or
other instrument, or result in the acceleration of, create any notice under any
agreement, contract, lease, license, instrument, or other arrangement to which
the Seller is a party or by which it may be bound or to which it may be subject,
or (iii) violate any provision of any of the organizational documents of the
Seller, including but not limited to its certificate of incorporation and
bylaws.

            (g) Capitalization. The total number of shares of capital stock the
Seller is authorized to issue is 11,000,000 shares, consisting of 10,000,000
shares of Common Stock and 1,000,000 shares of Preferred Stock having a par
value of $1.75 per share (the "Preferred Stock"). As of Closing Date 4,506,240
shares of Common Stock were issued; outstanding and 50,000 shares of Common
Stock were held in Treasury; and options to purchase an aggregate of 550,000
were outstanding. As of the Closing Date, none of the shares of Preferred Stock
are issued or outstanding.

         All of the issued and outstanding shares of Common Stock of the Seller
have been duly authorized, are validly issued, fully paid, and nonassessable,
and are held of record by 174 Seller's Disclosure Schedule, there are no
outstanding or authorized options, warrants, purchase rights, subscription
rights, conversion rights, exchange rights, or other contracts or commitments
that could require the Seller to issue, sell or otherwise cause to become
outstanding any of its capital. There are no outstanding or authorized stock
appreciation, phantom stock, profit participation or similar rights with respect
to the Seller. There are no voting trusts, proxies or other arrangements or
understandings with respect to the voting capital stock of the Seller.

                                       6
<PAGE>

            (h) Subsidiaries. The Seller does not own, directly or indirectly,
any equity or other ownership interest in any subsidiary, corporation,
partnership, joint venture or other entity.

            (i) Brokers' Fees. The Seller has no liability or obligation to pay
any commissions to any broker, finder, or agent with respect to the transactions
contemplated by this Agreement for which the Buyer could become obligated.

            (j) SEC Filings; SEC Financial Statements.

                (i) The Seller has filed all forms, reports and documents
required to be filed with the SEC since December 31, 1994, and has heretofore
made available to Buyer, in the form filed with the SEC, its (A) annual reports
on Form 10-KSB for the fiscal years ended October 31, 1999 and 1998 (including
all amendments prior to the date hereof), (B) all proxy statements relating to
the Seller's meetings of its stockholders (whether annual or special) held since
October 31, 1998 and (C) all other forms, reports, registrations, schedules,
statements and other documents required to be filed by the Seller since October
31, 1998 with the SEC pursuant to the Exchange Act or the Securities Act (as
such documents referred to herein have been amended since the time of their
filing, collectively, the "SEC Reports"). As of their respective dates, or, if
amended, as of the date of the last such amendment, the SEC Reports, including
without limitation, any financial statements or schedules included therein (the
"SEC Financial Statements") (A) complied in all material respects with the
applicable requirements of the Exchange Act and the Securities Act, as the case
may be, and the applicable rules and regulations of the SEC promulgated
thereunder, and (B) did not contain any untrue statement of a material fact or
omit to state a material fact required to be stated therein or necessary in
order to make the statements therein, in the light of the circumstances under
which they were made, not misleading.

                (ii) The SEC Financial Statements have been prepared from, and
are in accordance with the books and records of the Seller, comply in all
material respects with applicable accounting requirements and with the published
rules and regulations of the SEC with respect thereto, have been prepared in
accordance with GAAP applied on a consistent basis throughout the periods
involved (except as may be indicated in the notes thereto) and fairly presented
the financial position of the Seller and its results of operation, cash flows
and changes in financial position as of and for the periods indicated, except
that the unaudited interim financial statements contained in the SEC Reports
were or are subject to normal and recurring year-end adjustments.

            (k) Events Subsequent to the Most Recent Fiscal Year End. Except as
disclosed in paragraph 5(k) of the Seller's Disclosure Schedule, since October
31, 1999, the Seller has conducted its business only in the Ordinary Course of
Business and there has not been any material adverse change in the business,
financial condition, results of operations, or future prospects of the Seller.
Without limiting the generality of the foregoing, since October 31, 1999:

                (i) there have not occurred any events or changes (including the
incurrence of any liabilities of any nature, whether or not accrued, contingent
or otherwise) having, individually or in the aggregate, a material adverse
effect upon the present or future financial condition or the future results of
operations of the Seller;

                                       7
<PAGE>

                (ii) the Seller has not sold, leased, transferred, or assigned
any of its assets, tangible or intangible, other than for a fair consideration
in the Ordinary Course of Business;

                (iii) the Seller has not entered into any agreement, contract,
lease or license (or series of related agreements, contracts, leases, or
licenses) either involving more than $50,000 or outside the Ordinary Course of
Business;

                (iv) the Seller has not delayed or postponed the payment of
accounts payable and other Liabilities outside the Ordinary Course of Business;

                (v) there has been no change made or authorized in the
certificate of incorporation or bylaws of the Seller;

                (vi) except as set forth in Seller's Disclosure Schedule, the
Seller has not issued, sold, or otherwise disposed of any of its capital stock,
or granted any options, warrants or other rights to purchase or obtain
(including conversion, exchange or exercise) any of its capital stock ;

                (vii) the Seller has not made any loan to, or entered into any
other transaction with, any of its directors, officers and employees outside the
Ordinary Course of Business;

                (viii) the Seller has not made or pledged to make any charitable
or other capital contribution outside the Ordinary Course of Business;

                (ix) there has not been any other material adverse occurrence,
event, incident, action, failure to act or transaction outside the Ordinary
Course of Business involving the Seller; and

                (x) the Seller has not committed to any of the foregoing.

            (l) Undisclosed Liabilities. The Seller has no Liability (and there
is no basis for any present or future action, suit, proceeding, hearing,
investigation, charge, complaint, claim, or demand against the Seller), except
for (i) material Liabilities set forth in the SEC Financial Statements
(including in any notes thereto) and (ii) material Liabilities which have arisen
after the most recent interim financial statements included in the SEC Financial
Statements in the Ordinary Course of Business (none of which results from,
arises out of, relates to, is in the nature of, or was caused by any breach of
contract, breach of warranty, tort, infringement or violation of law) .

            (m) Legal Compliance. The Seller has materially complied with all
applicable laws (including rules, regulations, codes, plans, injunctions,
judgments, orders, decrees, rulings and charges thereunder) of federal, state ,
local and foreign governments (and all agencies thereof) and Seller has no
Knowledge of any action, suit, proceeding, hearing, investigation, charge,
complaint, claim, demand or notice having been filed or commenced against it
alleging any failures to so comply, except where any such noncompliance, or
alleged noncompliance if proven, would not either individually or in the

                                       8
<PAGE>

aggregate have a material adverse affect upon the financial condition or results
of operations of Seller.

            (n) Taxes.

                (i) (A) Subject to any extension which have been obtained,
Seller has timely filed with the appropriate Tax Authority all Tax Returns
required to be filed by or with respect to the Seller, and such Tax Returns are
true, correct and complete in all material respects; (B) all Taxes due and
payable by the Seller, with respect to the taxable years or other taxable
periods ending on or prior to the Closing Date have been or on or prior to the
Closing Date will be, paid or adequately disclosed and fully provided for; (C)
no Audits are pending or, to the Knowledge of the Seller, threatened with regard
to any Taxes or Tax Returns of the Seller and there are no outstanding
deficiencies or assessments asserted or, to the Knowledge of the Seller,
proposed; (D) no issue has been raised by any Taxing Authority in any Audit of
the Seller that if raised with respect to any other period not so audited could
reasonably be expected to result in a proposed deficiency of any period not so
audited that would have a material adverse effect upon the financial condition
or results of operations of the Seller; (E) there are no outstanding agreements,
consents or waivers extending the statutory period of limitations applicable to
the assessment of any Taxes or deficiencies against the Seller, and the Seller
is not a party to any agreement providing for the allocation or sharing of
Taxes; and (F) no powers of attorney with respect to Taxes of the Seller have
been executed that will be outstanding as of the Closing Date.

                (ii) The Seller has not filed a consent to the application of
Section 341(f) of the Code.

                (iii) The Seller has not been a United States real property
holding company (as defined in Section 897(c)(2) of the Code) during the
applicable period specified in Section 897(c)(1)(ii) of the Code.

                (iv) No indebtedness of the Seller is "corporate acquisition
indebtedness" within the meaning of Section 279(b) of the Code.

                (v) The Seller has not entered into any agreements that would
result in the disallowance of any tax deductions pursuant to Section 280G of the
Code.

                (vi) There are no liens for Taxes upon any of the assets of the
Seller, except for Liens for Taxes not yet due and payable for which adequate
reserves have been established on the Seller's balance sheet at October 31, 1999
included in the Seller's Annual Report on Form 10-KSB filed with the SEC prior
to the date hereof in accordance with GAAP.

                (vii) The Seller has disclosed all material Tax elections to
Buyer.

            (o) Real Property. Paragraph 5(o) of Seller's Disclosure Schedule
sets forth a complete list and description of all real property owned by the
Seller (the "Real Property"). The Seller has good and marketable title to the
Real Property. There are no existing or, to Seller's Knowledge, threatened
proceedings, claims, condemnation proceedings, lawsuits, administrative actions,
disputes or conditions affecting any Real Property that might curtail or
interfere in any material respect with the use of such property, nor is an
action of eminent domain pending or to the Knowledge of the Seller, threatened

                                       9
<PAGE>

for all or any portion of the Real Property. Except as disclosed in paragraph
5(o) of the Seller's Disclosure Schedule, the Seller is not a party to any
lease, assignment or similar arrangement under which the Seller is a lessor,
assignor or otherwise makes available for use by any third party any portion of
the Real Property. The Seller has obtained all appropriate material licenses,
permits, easements and rights of way, including proofs of dedication, required
to use and operate the Real Property in all material respects in the manner in
which the Real Property is currently being used and operated.

            (p) Title and Condition of Properties. The Seller has good and
marketable title, free and clear of all liens, to its personal property and
assets shown on the most recent balance sheet of the SEC Financial Statements or
acquired thereafter, except for (i) assets which have been disposed of to
nonaffiliated third parties since the date of the most recent balance sheet of
the SEC Financial Statements in the Ordinary Course of Business, liens or
imperfections of title which are not, individually or in the aggregate, material
in character, amount or extent and which do not materially detract from the
value or materially interfere with the present or presently contemplated use of
the assets subject thereto or affected thereby, and (iii) liens for current
Taxes not yet due and payable.

            (q) Intellectual Property.

                (i) Paragraph 5(q) of the Seller's Disclosure Schedule contains
a true and complete list of all material (A) patents and patent applications,
(B) trademark registrations and applications, (C) service mark registrations and
applications, (D) Computer Software (as hereinafter defined)(excluding Computer
Software generally available for purchase by the public), (E) copyright
registrations and applications, (F) unregistered trademarks, service marks, and
copyrights, and (G) Internet domain names used or held for use in connection
with the business of the Seller, together with all licenses related to the
foregoing.

                (ii) The term "Computer Software" shall mean (A) any and all
computer programs and applications consisting of sets of statements and
instructions to be used directly or indirectly in computer software or firmware
whether in source code or object code form, (B) databases and compilations,
including without limitation any and all data and collections of data, whether
machine readable or otherwise, (C) all versions of the foregoing including,
without limitation, all screen displays and designs thereof, and all component
modules of source code or object code or natural language code therefor, and
whether recorded on papers, magnetic media or other electronic or non-electronic
device, (D) all descriptions, flowcharts and other work product used to design,
plan, organize and develop any of the foregoing, (E) all documentation,
including without limitation all technical and user manuals and training
materials, relating to the foregoing, and all Internet domain names and content
contained on all world wide web sites of the Seller.

                (iii) The Seller owns or has the valid right to use all of the
Intellectual Property used by it or held for use by it in connection with its
business. The Seller is the sole and exclusive owner of all patents, patent
applications, patent rights, copyrights, trademarks, trademark rights, trade
names, trade name rights, and service marks, and all goodwill of the business
associated therewith, trade secrets, registrations for and applications for
registration of trademarks, service marks and copyrights, technology and
know-how, Computer Software other than off-the-shelf applications and other
confidential or proprietary rights and information made or used in connection

                                       10
<PAGE>

with any of the foregoing, used or held for use anywhere in the world in
connection with its business as currently conducted (collectively, the
"Intellectual Property"), free and clear of all material Liens.

                (iv) All grants, registrations and applications for Intellectual
Property that are used in and are material to the conduct of the business of the
Seller as currently conducted (A) are valid, subsisting, in proper form and
enforceable, and have been duly maintained, including the submission of all
necessary filings and fees in accordance with the legal and administrative
requirements of the appropriate jurisdictions and (B) have not lapsed, expired
or been abandoned, and no application or registration therefor is the subject of
any legal or governmental proceeding before any governmental, registration or
other authority in any jurisdiction, except to the extent where the absence of
such Intellectual Property would not have a material adverse effect upon the
financial condition or results of operations of the Seller.

                (v) To the Knowledge of the Seller, there are no conflicts with
or infringements of any Intellectual Property by any third party. The conduct of
the respective businesses of the Seller as currently conducted does not conflict
with or infringe in any way on any proprietary right of any third party. There
is no claim, suit, action or proceeding pending or, to the Knowledge of the
Seller, threatened against the Seller (A) alleging any such conflict or
infringement with any third party's proprietary rights, or (B) challenging the
ownership, use, validity or enforceability of the Intellectual Property.

                (vi) The Seller is not, nor will it be as a result of the
execution and delivery of this Agreement or the performance of its obligations
under this Agreement, in breach of any material license, sublicense or other
agreement relating to the Intellectual Property, except where any such
breach(es) will not individually or in the aggregate have a material adverse
affect upon the financial condition or results of operations of Seller.

                (vii) No former or present employees, officers or directors of
the Seller hold any right, title or interest directly or indirectly, in whole or
in part, in or to any Intellectual Property.

            (r) Contracts.

                (i) The SEC Reports contain a list of all material contracts to
which the Seller is a party or by which the Seller is bound.

                (ii) The Seller has filed with the SEC a correct and complete
copy of each of the written agreements referenced in Section 5(r)(i) above.

                (iii) With respect to each agreement referenced in Section
5(r)(i) above, each agreement is: (A) legal, valid, binding, enforceable and in
full force and effect; (B) will continue to be legal, valid, binding,
enforceable, and in full force and effect on identical terms following the
consummation of the transactions contemplated hereby; (C) Seller has no
Knowledge that any other party to any such agreement is in material breach or
default, and Seller has no Knowledge that any event has occurred which with
notice or lapse of time would constitute a breach or default, or permit
termination, modification, or acceleration, under the agreement, and (D) Seller
has no Knowledge that any other party has repudiated any provision of the
agreement.

                                       11
<PAGE>

            (s) Litigation. There are no claims, judgments, orders, decrees,
rulings, charges, actions, suits, proceedings, (including, without limitation,
arbitration proceedings), injunctions or alternative dispute resolution
proceedings, or investigations pending or, to the Knowledge of the Seller,
threatened against the Seller or any properties or rights of the Seller, before
any court or quasi-judicial or administrative agency of any federal, state,
local or foreign jurisdiction or before any arbitrator that, either individually
or in the aggregate would be reasonably likely to have a material adverse effect
upon the financial condition or the results of operations of the Seller. As of
the date hereof, the Seller is not subject to any material outstanding order,
judgment, injunction or decree.

            (t) Employees. To the best Knowledge of the Seller, no executive,
key employee or group of employees has any plans to terminate employment with
the Seller. The Seller is not a party to any collective bargaining agreement.
The Seller has not experienced any strike, grievance, claim of unfair labor
practice or other collective bargaining disputes. The Seller has not committed
any unfair labor practice. To the best Knowledge of the Seller, no
organizational effort presently is being made or threatened by or on behalf of
any labor union with respect to employees of the Seller. The Seller has complied
in all material respects with all applicable laws relating to employment,
employment discrimination and employment practices.

            (u) Employee Benefit Plans (see MAS Employee Stock Option Plan).

                (i) Paragraph 5(u) of the Seller's Disclosure Schedule sets
forth a list of all "Employee Welfare Benefit Plans" (as defined in Section 3(l)
of the Employee Retirement Income Security Act of 1974, as amended ("ERISA"),
"Employee Pension Benefit Plans" (as defined in Section 3(2) of ERISA),
employment agreements and all other bonus, stock option, stock purchase,
benefit, profit sharing, savings, retirement, disability, insurance, incentive,
deferred compensation and other similar fringe or employee benefit plans,
programs or arrangements for the benefit of, or relating to, any employee of, or
independent contractor or consultant to, the Seller (together, the "Employee
Plans"). With respect to each Employee Plan, the Seller has made available to
Buyer true and complete copies of (A) all plan documents, as in effect on the
date hereof, and will make available all other employee plans, together with all
amendments thereto which will become effective at a later date, (B) the latest
Internal Revenue Service determination letter, (C) the last filed Form 5500, (D)
summary plan description, if any, and all modifications thereto communicated to
employees, and (E) the most recent annual and periodic accounting of related
plan assets, if any. Neither the Seller, its directors, officers, employees or
agents has, with respect to any Employee Plan, engaged in or been a party to any
"prohibited transaction," as such term is defined in Section 4975 of the Code or
Section 406 of ERISA, which could result in the imposition of either a material
penalty assessed pursuant to Section 502(i) of ERISA or a material tax imposed
by Section 4975 of the Code, in each case applicable to the Seller or any
Employee Plan. All Employee Plans are in compliance in all material respects
with the currently applicable requirements prescribed by all statutes, orders,
or governmental rules or regulations currently in effect with respect to such
Employee Plans, including, but not limited to, ERISA and the Code and, to the
Knowledge of the Seller, there are no pending or threatened claims, lawsuits or
arbitrations (other than routine claims for benefits), relating to any of the
Employee Plans, which have been asserted or instituted against the Seller, any
Employee Plan or the assets of any trust for any Employee Plan. Each Employee
Plan intended to qualify under Section 401(a) of the Code, and the trusts
created thereunder intended to be exempt from tax under the provisions of
Section 501(a) of the Code has received a favorable determination letter from
the Internal Revenue Service to such effect or is still within the "remedial

                                       12
<PAGE>

amendment period." No Employee Plan is a "Multiemployer Plan" (as defined in
Section 3(37) of ERISA) or is subject to Title IV of ERISA. The Seller has fully
complied with the provisions of Section 4980B of the Code and Part 6 of Title I
of ERISA. The requirements of COBRA have been met with respect to each such
Employee Plan which is an Employee Welfare Benefit Plan. All contributions
(including employer contributions and employee salary reduction contributions)
which are due have been paid to each such Employee Plan which is an employee
benefit pension plan and all contributions for any period ending on or before
the Closing Date which are not yet due have been paid to each such employee
benefit pension plan or accrued in accordance with the past custom and practice
of the Seller. All premiums or other payments for all periods ending on or
before the Closing Date have been paid with respect to each such Employee Plan
which is an Employee Welfare Benefit Plan.

                (ii) All required reports and descriptions (including Form 5500
Annual Reports, summary annual reports, PBGC-1s, and summary plan descriptions)
have been timely filed and distributed appropriately with respect to each such
Employee Plan.

                (iii) The market value of assets under each such Employee Plan
which is an Employee Pension Benefit Plan equals or exceeds the present value of
all vested and nonvested Liabilities thereunder determined in accordance with
PBGC methods, factors and assumptions applicable to an Employee Pension Benefit
Plan terminating on the date for determination.

            (v) Guaranties. The Seller is not a guarantor or otherwise liable
for any Liability or obligation (including indebtedness) of any other Person.

            (w) Environmental Matters. Except for matters disclosed in paragraph
5(w) of the Seller's Disclosure Schedule:

                (i) The Seller is in compliance with all Environmental Laws, and
the Seller has not received written notice of any outstanding allegations by any
person or entity that the Seller is not or has not been in compliance (unless
such non-compliance has been cured) with any Environmental Laws.

                (ii) The Seller currently holds all material permits, licenses,
registrations and other governmental authorizations and financial assurances
required under any Environmental Laws for the Seller to operate its business
except for such permits, licenses, registrations and other governmental
authorization and financial assurances, the failure of the Seller to hold is not
reasonably expected to result in a material adverse effect upon the financial
condition or the results of operations of the Seller.

                (iii) To the best of the Seller's Knowledge, there is no
asbestos or asbestos-containing materials in or on any real property, buildings,
structures or components thereof currently owned, leased or operated by the
Seller. To the best of the Seller's Knowledge, there are and have been no
underground or aboveground storage tanks (whether or not required to be
registered under any applicable law), dumps, landfills, lagoons, surface
impoundments, sumps, injection wells or other disposal or storage sites or
locations in or on any property currently owned, leased or operated by the

                                       13
<PAGE>

Seller for any matter that is reasonably expected to result in a material
adverse effect upon the financial condition or the results of operations of the
Seller.

                (iv) The Seller has not received (A) any communication from any
person stating or alleging that it is or may be a potentially responsible party
under any Environmental Law (including, without limitation, the Comprehensive
Environmental Response, Compensation and Liability Act of 1980, as amended, and
any state analog thereto) with respect to any actual or alleged environmental
contamination or (B) any request for information under any Environmental Law
from any governmental agency or authority or any other person or entity with
respect to any active or alleged environmental contamination or violation.

                (v) The Seller is not a party to any pending judicial or
administrative proceedings alleging that it is a potentially responsible party
under the Comprehensive Environmental Response, Compensation, and Liability Act
of 1980, as amended, and any state analog thereto) or otherwise liable or
responsible with respect to any actual or alleged environmental contamination.

                (vi) No governmental agency or authority, or any other person or
entity is conducting and has not conducted (nor is proposing or threatening to
conduct) any environmental remediation or investigation of the Seller.

            (x) Health and Safety. The Seller has not received any written or
oral notice, report or other information regarding any actual or alleged
violation of Health and Safety Requirements, or any Liabilities, including any
investigatory, remedial or corrective obligations, relating to Seller or its
facilities arising under Health and Safety Requirements.


            (y) Insurance Policies. All material policies of fire, liability,
workmen's compensation and other similar forms of insurance owned or held by the
Seller are in full force and effect, and no notice of cancellation or
termination has been received with respect to any such policy. Such policies are
valid, outstanding and enforceable policies, and will not in any way be affected
by, or terminate or lapse by reason of, the transactions contemplated by this
Agreement. Such policies, provide, to the Knowledge of the Seller, insurance
coverage that is adequate for the assets and operations of the Seller. Since
October 31, 1997, the Seller has been covered by insurance in scope and amount
customary and reasonable for the business in which it has engaged during such
period.

         6. Representations and Warranties of the Buyer. The Buyer represents
and warrants to the Seller that the statements contained in this Section 6 are
correct and complete as of the date of the Closing Date. The Buyer represents
and warrants to the Seller as follows:

            (a) No Registration of the Shares. The Buyer understands that: (i)
the Shares are being sold to the Buyer under one or more exemptions from the
registration provisions of the Securities Act; (ii) the Buyer is purchasing such
Shares without being furnished any offering literature or prospectus other than
the information set forth herein and publicly disseminated information regarding
the Seller and its Common Stock; and (iii) the sale of the Shares has not been

                                       14
<PAGE>

examined by the SEC or by any agency charged with the administration of the
securities laws of any state or other jurisdiction. The Buyer represents and
warrants that it is an accredited investor as defined in Rule 501 under
Regulation D of the Rules of the United States Securities and Exchange
Commission under the Securities Act and that it has such Knowledge and
experience in financial and business matters that it is capable of evaluating
the merits and risks of an investment in the Shares and of making an informed
investment decision with respect thereto. The Buyer understands that the Seller
is relying on the truth and accuracy of the representations, declarations and
warranties made herein by the Buyer in selling the Shares hereunder without
having first registered such Shares under the Securities Act or under the
securities laws of any state or other jurisdiction.

            (b) Investment Intent. The Buyer confirms that: (i) it understands
that there are substantial restrictions on the transferability of the Shares
and, accordingly, it may not be possible for it to liquidate its investment in
the Shares in case of emergency; and (ii) it is able to bear the economic risk
of this investment in the Shares, to hold the Shares for an indefinite period of
time, and currently to afford a complete loss of this investment. The Shares
being acquired by the Buyer hereunder are being acquired in good faith solely
for its own account, for investment purposes only, and are not being purchased
with a view to or for the resale, distribution, subdivision or fractionalization
thereof. The Buyer does not have any contract, undertaking, understanding,
agreement or arrangement, formal or informal, with any person to sell, transfer
or pledge to any person the Shares being acquired hereunder, or any part
thereof, and has no current plan to enter into any such contract, undertaking,
agreement or arrangement. The Buyer understands that the legal consequences of
the foregoing representations and warranties are that it must bear the economic
risk of this investment in the Shares for an indefinite period of time because
the Shares have not been registered under the Securities Act.

            (c) Decision to Invest. The Buyer confirms that, in making its
decision to invest in the Shares, it has relied solely upon independent
investigations made by it or its representatives and advisors, and that it and
such representatives and advisors have been given the opportunity to ask
questions of, and to receive answers from, management of the Seller with respect
to the Seller and the Seller's Common Stock.

            (d) Organization of the Buyer. The Buyer is a corporation duly
organized, validly existing and in good standing under the laws of the
jurisdiction of its incorporation.

            (e) Authority. The Buyer has the corporate power to execute, deliver
and carry out the terms and provisions of this Agreement and has taken all
necessary corporate action to authorize the execution, delivery and performance
of this Agreement by the Buyer. This Agreement constitutes the valid and legally
binding obligation of the Buyer, enforceable in accordance with its terms and
conditions.

            (f) No Consent Required. No authorization, consent or approval of,
or exemption by, any governmental or public body or authority is required to
authorize, or is required in connection with, the execution, delivery and
performance of any of this Agreement, or the taking of any action contemplated
hereby, by the Buyer, except those that have been obtained or are available.

            (g) No Violation. Neither the execution and delivery of this
Agreement, nor compliance with any of the terms and provisions hereof, nor the

                                       15
<PAGE>

consummation of any of the transactions herein contemplated will not violate any
provision of any of the organizational documents of the Buyer, including but not
limited to its charter and bylaws.

            (h) Brokers' Fees. The Buyer has no liability or obligation to pay
any commissions to any broker, finder, or agent with respect to the transactions
contemplated by this Agreement for which the Seller could become obligated.

         7. Securities Law Matters and Restrictions on the Shares.

            (a) Permitted Transfers.

                (i) The Buyer understands and agrees that the Shares being
purchased hereunder may be transferred by it only pursuant to (A) a public
offering thereof registered under the Securities Act, (B) Rule 144 of the SEC
(or any similar rule in force at the time of such transfer) if such rule is
available, and (C) any other legally available means of transfer.

                (ii) In connection with the transfer of any Shares, the Buyer
shall deliver written notice to the Seller describing in reasonable detail the
transfer or proposed transfer, together with an opinion of counsel that is
knowledgeable in securities law matters and reasonably acceptable to the Seller,
to the effect that such transfer may be effected without registration under the
Securities Act and under applicable state securities laws.

            (b) Restrictive Legend. Each certificate for the Shares, and any
shares of capital stock received in respect thereof, whether by reason of a
stock split or share reclassification thereof, a stock dividend thereon or
otherwise, shall be stamped or otherwise imprinted with a legend in
substantially the following form:

            THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED
            FOR INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT
            OF 1933 OR THE SECURITIES LAWS OF ANY STATE. THESE SECURITIES MAY
            NOT BE SOLD OR TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR AN
            EXEMPTION THEREFROM UNDER SUCH ACT AND APPLICABLE STATE SECURITIES
            LAWS.

            (c) Current Public Information. The Seller shall use its best
efforts to file all reports required to be filed by it under the Exchange Act
and the rules and regulations thereunder and shall take such further action as
any holder of any Shares may reasonably request, all to the extent required to
enable any such holder to sell Shares pursuant to Rule 144 under the Securities
Act (as such rule may be amended from time to time) or any similar rule or
regulation then in force. Upon written request, the Seller shall deliver to any
holder of any Shares a written statement as to whether it has complied with such
requirements.

            (d) Compliance with Securities Laws. The Buyer acknowledges that it
is required to comply with the provisions of the Exchange Act and other
applicable rules and regulations relating to its ownership of the Seller's
Common Stock. The Buyer agrees to comply in all respects with the provisions of
the Exchange Act and other applicable rules and regulations, to file all reports

                                       16
<PAGE>

required to be filed by it thereunder and to supply the Seller with all
information requested by it from time to time in order to permit the Seller to
comply with the provisions of the Exchange Act and other applicable laws, rules
and regulations.

         8. Closing Covenants.  Each of the Parties agree as follows.

            (a) General. Each of the Parties will use its reasonable best
efforts to take all action and to do all things necessary, proper or advisable
in order to consummate and make effective the transactions contemplated by this
Agreement.

            (b) Use of Proceeds. Seller agrees to use the proceeds from the sale
of the Shares in accordance with Section 2(c) above.

            (c) License Agreement. The Seller and the Buyer's wholly-owned
subsidiary, eRT, shall enter into the Licensing Agreement.

            (d) Services Agreement. The Seller and the Buyer's wholly- owned
subsidiary, eRT, shall enter into the Services Agreement.

            (e) Notices and Consents. The Seller will give any notice to third
parties, and will use its reasonable best efforts to obtain any third party
consents, if any, that the Buyer may reasonably request in connection with the
matters in Section 5(f). Each of the Parties will give any notices to, make any
filings with, and use its reasonable best efforts to obtain any required
authorizations, consents and approvals of governments and governmental agencies
in connection with the transactions contemplated herein.

            (f) Right of First Refusal . The Seller will not engage in any
practice, or take any action or enter into any transaction in violation of
Section 3 of this Agreement.

            (g) Preservation of Business. The Seller will keep its business and
properties substantially in tact, including its present operations, physical
facilities, working conditions and relationships with lessors, licensors,
suppliers, customers and employees.

            (h) Full Access. The Seller will permit the Buyer, or its
representatives, to have the full access accorded to shareholders of the Buyer
and as authorized with respect to eRT under the License Agreement and the
Services Agreement at all reasonable times, and in a manner so as not to
interfere with the normal business operations of the Seller to all premises,
properties, books, and records (including Tax records), contracts and documents
of or pertaining to the Seller. No disclosure by the Seller hereunder shall be
deemed to amend or supplement the Seller's Disclosure Schedule or to prevent or
cure any misrepresentation, breach of warranty or breach of agreement.

            (i) Notice of Developments. The Seller will give prompt written
notice to the Buyer of any material adverse development causing a breach of any
of the representations and warranties in Section 5 above. The Buyer will give
prompt written notice to the Seller of any material adverse development causing
a breach of any of the representations and warranties in Section 6 above.

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         9. Remedies for Breaches of this Agreement.

            (a) Survival of Representations and Warranties. All of the
representations, warranties, covenants, and obligations in this Agreement, the
Seller's Disclosure Schedule, any certificates and documents delivered pursuant
to this Agreement will survive for a period of one (1) year Closing.

            (b) Indemnification Provisions for the Benefit of the Buyer. In the
event the Seller breaches (or in the event that any third party alleges facts
that, if true, would mean the Seller has breached) any of its representations
and warranties, and covenants contained herein, provided that the Buyer makes a
written claim for indemnification against the Seller pursuant to the
notification requirements of Section 10(g) below, then the Seller agrees to
indemnify the Buyer from and against the entirety of any Adverse Consequences
the Buyer may suffer through and after the date of the claim for indemnification
(including any Adverse Consequences the Buyer may suffer after the end of any
applicable survival period) resulting from, arising out of, relating to, in the
nature of, or caused by the breach or alleged breach.

            (c) Matters Involving Third Parties.

                (i) If any third party shall notify any Party (the "Indemnified
Party") with respect to any matter (a "Third Party Claim") which may give rise
to a claim for indemnification against the other Party (the "Indemnifying
Party") under this Section 10, then the Indemnified Party shall promptly notify
the Indemnifying Party thereof in writing; provided, however, that no delay on
the part of the Indemnified Party in notifying any Indemnifying Party shall
relieve the Indemnifying Party from any obligation hereunder unless (and then
solely to the extent) the Indemnifying Party thereby is prejudiced.

                (ii) Any Indemnifying Party will have the right to defend the
Indemnified Party against the Third Party Claim with counsel of the Indemnifying
Party's choice reasonably satisfactory to the Indemnified Party so long as (A)
the Indemnifying Party notifies the Indemnified Party in writing within 15 days
after the Indemnified Party has given notice of the Third Party Claim that the
Indemnifying Party will indemnify the Indemnified Party from and against the
entirety of any Adverse Consequences the Indemnified Party may suffer resulting
from, arising out of, relating to, in the nature of, or caused by the Third
Party Claim, (B) the Indemnifying Party provides the Indemnified Party with
evidence reasonably acceptable to the Indemnified Party that the Indemnifying
Party will have the financial resources to defend against the Third Party Claim
and fulfill its indemnification obligations hereunder, (C) settlement of, or an
adverse judgment with respect to, the Third Party Claim is not, in the good
faith judgment of the Indemnified Party, likely to establish a precedential
custom or practice materially adverse to the continuing business interests of
the Indemnified Party, and (D) the Indemnifying Party conducts the defense of
the Third Party Claim actively and diligently.

                (iii) So long as the Indemnifying Party is conducting the
defense of the Third Party Claim in accordance with Section 9(c)(ii) above, (A)
the Indemnified Party may retain separate co-counsel at its sole cost and
expense and participate in the defense of the Third Party Claim, (B) the
Indemnified Party will not consent to the entry of any judgment or enter into
any settlement with respect to the Third Party Claim without the prior written
consent of the Indemnifying Party, not to be withheld unreasonably, and (C) the
Indemnifying Party will not consent to the entry of any judgment or enter into

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any settlement with respect to the Third Party Claim without the prior written
consent of the Indemnified party, not to be withheld unreasonably.

                 (iv) In the event any of the conditions in Section 9(c)(ii) are
or become unsatisfied, (A) the Indemnified Party may defend against, and consent
to the entry of any judgment or enter into any settlement with respect to, the
Third Party Claim in any manner it reasonably may deem appropriate (and the
Indemnified Party need not consult with, or obtain any consent from the
Indemnifying Party in connection therewith), (B) the Indemnifying Party will
reimburse the Indemnified Party promptly and periodically for the costs of
defending against the Third Party Claim (including reasonable attorneys' fees
and expenses), and (C) the Indemnifying Party will remain responsible for any
Adverse Consequences the Indemnified Party may suffer resulting from, arising
out of, relating to, in the nature of, or caused by the Third Party Claim to the
fullest extent provided in this Section 9.

             (d) Other Indemnification Provisions. The foregoing indemnification
provisions are in addition to, and not in derogation of, any statutory,
equitable, or common law remedy (including without limitation any such remedy
arising under Environmental Laws and Health and Safety Requirements) any Party
may have with respect to the transactions contemplated by this Agreement.

         10. Miscellaneous.

             (a) Press Releases. No party shall issue any press release or make
any public announcement relating to the subject matter of this Agreement prior
to Closing without the prior written approval of the other Party, provided,
however, that any Party may make a public disclosure it believes in good faith
is required by applicable law or any listing or trading agreement concerning its
publicly-traded securities (in which case, the disclosing Party will use its
reasonable best efforts to advise the other Party prior to making the
disclosure).

             (b) No Third-Party Beneficiaries. This Agreement shall not confer
any rights or remedies upon any Person other than the Parties and their
respective successors and permitted assigns.

             (c) Choice of Law. This Agreement shall be construed and enforced
in accordance with and pursuant to the laws of the State of Delaware without
giving effect to any choice or conflict of law provision or rule (whether of the
State of Delaware or any other jurisdiction) that would cause the application of
the laws of any jurisdiction other than the State of Delaware.

             (d) Binding Effect. This Agreement shall be binding upon and inure
to the benefit of the Parties hereto and their respective heirs, successors,
personal representatives and assigns.

             (e) Entire Agreement. This Agreement, including the documents
referred to herein, constitutes the entire agreement between the Parties and
supersedes any prior understandings, agreements or representations by or between
the Parties, written or oral, to the extent they relate in any way to the
subject matter hereof.

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<PAGE>

             (f) Counterparts. This Agreement may be executed in multiple
counterparts, each of which shall be deemed an original Agreement, and all of
which shall constitute one Agreement to be effective as of the date of this
Agreement.

             (g) Notices. All notices, requests or other communications
hereunder shall be in writing and shall be deemed to have been duly given if
delivered in person or by courier; sent by overnight courier, charges prepaid;
or telegraphed, telexed or mailed by certified or registered mail, postage
prepaid, to the address of the respective Party set forth below:

         If to the Buyer:

             Premier Research Worldwide, Ltd.
             30 South 17th Street
             Philadelphia, PA 19103-4001
             Attention: Joel Morganrath, MD, Chairman and
                        Chief Executive Officer

             with a copy to:
             Duane, Morris & Heckscher LLP
             4200 One Liberty Place
             Philadelphia, PA  19103-7396
             Attention: Sheldon M. Bonovitz, Esquire

         If to the Seller:

             Medical Advisory Systems Inc.
             8050 Southern Maryland Blvd.
             Owings, MD  20736
             Attention:

             (h) Headings. The section headings contained in this Agreement are
inserted for convenience only and shall not affect in any way the meaning or
interpretation of this Agreement.

             (i) Amendments. No amendment of any provision of this Agreement
shall be valid unless the same shall be in writing and signed by the Buyer and
the Seller.

             (j) Severability. Any term or provision of this Agreement that is
invalid or unenforceable in any situation in any jurisdiction shall not effect
the validity or enforceability of the remaining terms and provisions hereof or
the validity or enforceability of the offending term or provision in any other
situation or in any other jurisdiction.

                                       20
<PAGE>

         IN WITNESS WHEREOF, the undersigned have hereunto executed this
Agreement the day and year first above written.

                                                MEDICAL ADVISORY SYSTEMS, INC.

                                                By: Ronald W. Pickett

                                                 Title:  President


                                                PREMIER RESEARCH WORLDWIDE, LTD.

                                                By: /s/ Joel Morganroth, M.D.

                                                 Title: /s/ Chairman and CEO




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