MERRILL LYNCH N Y MUNI BD FD OF M L MULTI ST MUNI SER TRUST
24F-2NT, 1995-11-21
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November 21, 1995



Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street N.W.
Washington, D.C.  20549

Re:  Rule 24f-2 Notice for
     MERRILL LYNCH NEW YORK
     MUNICIPAL BOND FUND OF
     MERRILL LYNCH MULTI-STATE 
     MUNICIPAL SERIES TRUST
     File No. 2-99473
     
Dear Sirs:

In accordance with the provisions 
of Rule 24f-2 under the Investment 
Company Act of 1940, Merrill 
Lynch New York Municipal Bond 
Fund (the "Fund") of Merrill Lynch 
Multi-State Municipal Series Trust 
(the "Trust") hereby files its Rule 
24f-2 Notice (the "Notice").

The Notice is being filed for the 
fiscal year of the Fund ended 
September 30, 1995 (the "Fiscal 
Year"). In addition to the Fund, 
the Trust consists of the following 
portfolios: Merrill Lynch New Jersey 
Municipal Bond Fund (File No. 
33-35441), Merrill Lynch Florida 
Municipal Bond Fund (File No.  
33-39555), Merrill Lynch Texas 
Municipal Bond Fund (File No.  
33-40480), Merrill Lynch Arizona 
Municipal Bond Fund (File No.  
33-41311), Merrill Lynch 
Pennsylvania Municipal Bond 
Fund (File No. 33-35442), Merrill 
Lynch Ohio Municipal Bond 
Fund (File No.  33-44500), Merrill 
Lynch Minnesota Municipal Bond 
Fund (File No.  33-44734), Merrill 
Lynch Massachusetts Municipal 
Bond Fund (File No. 33-35987), 
Merrill Lynch North Carolina 
Municipal Bond Fund (File No.  
33-48692), Merrill Lynch
Connecticut Municipal Bond 
Fund (File No. 33- 48693), Merrill 
Lynch Oregon Municipal Bond 
Fund (File No. 33-64502), Merrill 
Lynch New Mexico Municipal 
Bond Fund (File No. 33-52303), 
Merrill Lynch Michigan Municipal 
Bond Fund (File No. 33-55576), 
Merrill Lynch Maryland Municipal 
Bond Fund (File No. 33-49873), 
Merrill Lynch Arkansas Municipal 
Bond Fund (File No. 33-54341)
and Merrill Lynch Colorado 
Municipal Bond Fund (File No. 
33-50051) each of which has a 
Fiscal Year end of July 31 and 
files its Rule 24f-2 Notice 
accordingly.  Set forth below is 
the information required by Rule 
24f-2 for the Fund.
   
1. 1,462,313 shares of beneficial 
    interest of the Fund which had 
    been registered under the 
    Securities Act of 1933 (the 
    "Securities Act") other than
    pursuant to Rule 24f-2 
    remained unsold at the 
    beginning of the Fiscal Year.
   
2. 10,206,616 shares of beneficial 
    interest were registered under 
    the Securities Act during the 
    Fiscal Year other than pursuant 
    to Rule 24f-2.
   
3. 4,586,485 shares of beneficial 
    interest were sold during the 
    Fiscal Year.*
   
4. No shares of beneficial interest 
    were sold during the Fiscal Year 
    in reliance upon registration
    pursuant to Rule 24f-2.
   
   
Please direct any questions relating 
to this filing to Jerry Weiss, Merrill 
Lynch Asset Management, P.O. 
Box 9011, Princeton, NJ 08543,
(609)282-1727 or to Laurin 
Blumenthal Kleiman at Brown & 
Wood, 1 World Trade Center, 
New York, New York  10048, 
(212) 839-5525.


Very truly yours,


MERRILL LYNCH NEW YORK 
MUNICIPAL BOND FUND OF
MERRILL LYNCH MULTI-STATE 
MUNICIPAL SERIES TRUST



By /s/ Jerry Weiss
   - - - - - - - - - - -
     Jerry Weiss
      Secretary





















___________________
*Of this amount, 310,937 Class A shares were sold at an
aggregate price of $3,354,788, 3,667,182 Class B shares were
sold at an aggregate price of $39,752,322, 350,647 Class C
shares were sold at an aggregate price of $3,811,029 and
257,719 Class D shares were sold at an aggregate price of
$2,767,713.  The aggregate price of all shares of beneficial
interest sold during the Fiscal Year was $49,685,852.



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