MERRILL LYNCH N Y MUNI BD FD OF M L MULTI ST MUNI SER TRUST
24F-2NT, 2000-12-26
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                    U.S. SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549

                                  FORM 24F-2

                       Annual Notice of Securities Sold
                            Pursuant to Rule 24f-2



1.       Name and address of Issuer:

         Merrill Lynch New York Municipal Bond Fund of
         Merrill Lynch Multi-State Municipal Series Trust
         P.O. Box 9011
         Princeton, N.J.  08543-9011

2.       Name of each series or class of securities for which this Form is
         filed (if the Form is being filed for all series and classes of
         securities of the issuer, check the box but do not list
         series or classes):  [X]



3.       Investment Company Act File Number:       811-4375

         Securities Act File Number:               00299473

4.       (a)      Last day of fiscal year for which this Form is filed:
                  September 30, 2000

         (b)      [  ]   Check box if this Form is being filed late (i.e.,
                  more than 90 calendar days after the end of the issuer's
                  fiscal year).

         (c)      [  ]   Check box if this is the last time the issuer will be
                  filing this Form.

5.       Calculation of registration fees:

         (i)      Aggregate sales price of securities sold during
                  the fiscal year pursuant to Section 24(f):       $0

         (ii)     Aggregate price of securities redeemed or
                  repurchased during the fiscal year:              $80,388,160

         (iii)    Aggregate price of securities redeemed or
                  repurchased during any prior fiscal year ending
                  no earlier than October 31, 1995, that were not
                  previously used to reduce registration fees
                  payable to the Commission:                       $463,773,181

         (iv)     Total available redemption credits [add Items
                  5(ii) and 5(iii)]:                               $544,161,341

         (v)      Net sales - if Item 5(i) is greater than Item
                  5(iv)[subtract Item 5(iv) from Item 5(i)]:       $0

         (vi)     Redemption credits available for use in future
                  years - if Item 5(i) is less than Item 5(iv):    $544,161,341

         (vii)    Multiplier for determining registration fee
                  (see instruction C.9):                           .000250

         (viii)   Registration fee due [multiply Item 5(v)
                  by Item 5(vii) (enter "0" if no fee is due)]:    $0

6.       Prepaid Shares

         If the response to Item 5(i) was determined by deducting an amount of
         securities that were registered under the Securities Act of 1933
         pursuant to Rule 24e-2 as in effect before October 11, 1997, then
         report the amount of securities (number of shares or other units)
         deducted here: 2,290,285

         If there is a number of shares or other units that were registered
         pursuant to Rule 24e-2 remaining unsold at the end of the fiscal year
         for which this Form is filed that are available for use by the issuer
         in future fiscal years, then state that number here: 196,459

7.       Interest due - if this Form is being filed more than 90 days
         after the end of the issuer's fiscal year (see instruction D):     $0

8.       Total of the amount of the registration fee due plus any
         interest due [line 5(viii) plus line 7]:                           $0

9.       Date the registration fee and any interest payment was sent to the
         Commission's lockbox depository:

         Method of Delivery:

         [  ]  Wire Transfer

         [  ]  Mail or other means

<PAGE>

                                  SIGNATURES


This report has been signed below by the following persons on behalf of the
issuer and in the capacities and on the dates indicated:


By:


         /s/ Alice A. Pellegrino
--------------------------------
         Secretary


Date:  December 20, 2000



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