DIANON SYSTEMS INC
10-Q/A, 1996-11-15
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549
                                 ---------------

   
                                FORM 10-Q/A No. 1
    


   [X] QUARTERLY REPORT UNDER SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE
                                   ACT OF 1934

                For the Quarterly Period Ended September 30, 1996

                                       OR

    [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES
                              EXCHANGE ACT OF 1934
                        For the transition period from to

                         Commission file number 33-41226


                              DIANON SYSTEMS, INC.
             (exact name of registrant as specified in its charter)

              Delaware                                    06-1128081
      (State of incorporation)                (IRS Employer Identification No.)

    200 Watson Blvd, Stratford, CT                           06497
(Address of principal executive offices)                   (zip code)

       Registrant's telephone number, including area code: (203) 381-4000


                                 NOT APPLICABLE
              (Former name, former address and former fiscal year,
                          if changed since last report)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed  by  Section  13 or 15 (d) of the  Securities  Exchange  Act of 1934
during the preceding 12 months (or for such shorter  period that the  registrant
was  required  to file such  reports ) and (2) has been  subject to such  filing
requirements for the past 90 days.

                                                           Yes  X        No
                                                                

The number of shares of registrant's  Common Stock, $.01 par value,  outstanding
on November 8, 1996 was 6,707,680 shares.



                    Exhibit Index is on page 15 of 69 pages.


<PAGE>

                              DIANON SYSTEMS, INC.
                                AND SUBSIDIARIES


   
The registrant  hereby amends and restates in its entirety its Quarterly  Report
on Form 10-Q for the quarterly  period ended  September  30, 1996.  Other than a
change in the dollar amount set forth in the third  paragraph of "Liquidity  and
Capital  Resources" under Item 2, the information  contained in the registrant's
Quarterly  Report on Form 10-Q for the quarterly period ended September 30, 1996
as  originally  filed  with  the  Securities  and  Exchange  Commission  remains
unchanged.
    


                                      INDEX

<TABLE>
<CAPTION>

Part I FINANCIAL INFORMATION                                          PAGE NO.
- ----------------------------                                          --------

<S>       <C>                                                             <C>
Item 1.   FINANCIAL STATEMENTS

          Consolidated  Balance  Sheets as of September  30,              3
          1996 and December 31, 1995.

          Consolidated Income Statements for the three month              4
          and nine month  periods  ended  September 30, 1996
          and 1995.

          Consolidated  Statements of  Stockholders'  Equity              5
          for the twelve month  periods  ended  December 31,
          1995 and the nine month  periods  ended  September
          30, 1996.

          Consolidated Statements of Cash Flows for the nine              6
          month periods ended September 30, 1996 and 1995.

          Notes to Consolidated Financial Statements                      7


Item 2.   MANAGEMENT'S DISCUSSION AND ANALYSIS OF
          FINANCIAL CONDITION AND RESULTS OF OPERATIONS.                  8-12


Part II OTHER INFORMATION
- -------------------------

Item 5.   OTHER INFORMATION                                               13

Item 6.   EXHIBITS AND REPORTS ON  FORM 8-K                               13

Signatures                                                                14

Exhibit Index                                                             15

</TABLE>

<PAGE>

                    DIANON SYSTEMS, INC.
                 CONSOLIDATED BALANCE SHEETS

<TABLE>
<CAPTION>

                                                                         SEPTEMBER 30,       DECEMBER 31,
                                                                              1996               1995
    ASSETS                                                               -------------       ------------ 
CURRENT ASSETS:                                                           (UNAUDITED)
<S>                                                                       <C>                <C>
    Cash and cash equivalents                                             $  5,961,279       $ 10,990,231
    Accounts receivable, net of allowances of $786,920
          for each of the periods                                           12,490,911          9,653,971
    Prepaid expenses and employee advances                                   1,128,987          1,071,963
    Prepaid and refundable income taxes                                        434,064            168,420
    Inventory                                                                  633,694            554,398
    Deferred income tax asset                                                  652,328            652,328
    Investment in common stock                                                      --            135,508
                                                                          ------------       ------------
          Total current assets                                              21,301,263         23,226,819
                                                                          ------------       ------------
 PROPERTY AND EQUIPMENT, at cost
    Leasehold improvements                                                   3,631,986          1,717,606
    Laboratory and office equipment                                         12,105,424         11,068,949
          Less - accumulated depreciation                                   (8,026,792)        (6,879,799)
                                                                          ------------       ------------
                                                                             7,710,618          5,906,756
                                                                          ------------       ------------
INTANGIBLE ASSET - CUSTOMER LISTS, net of
    accumulated amortization of $2,731,009 and $2,606,291, respectively        614,595            739,308
INTANGIBLE ASSET - NON COMPETE AGREEMENT, net of
    accumulated amortization of $162,500 and $125,000, respectively             87,500            125,000
DEFERRED INCOME TAX ASSET                                                      178,575            178,575
OTHER ASSETS                                                                   239,419            278,948
                                                                          ------------       ------------
          TOTAL ASSETS                                                    $ 30,131,970       $ 30,455,406
                                                                          ============       ============
    LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES:
    Accounts payable and accrued liabilities                              $  5,925,583       $  4,922,514
    Current portion of capitalized lease obligations                            36,760             38,466
    Current portion of note payable                                            884,514            916,150
    Severance costs                                                            101,683            209,121
    Restructuring reserves                                                     155,584            166,598
                                                                          ------------       ------------
          Total current liabilities                                          7,104,124          6,252,849
                                                                          ------------       ------------
LONG-TERM PORTION OF CAPITALIZED LEASE
    OBLIGATIONS                                                                 75,525             34,413
LONG-TERM NOTE PAYABLE                                                              --            650,154
DEFERRED INCOME TAX LIABILITY                                                   65,651             65,651
                                                                          ------------       ------------
          Total Liabilities                                                  7,245,300          7,003,067
                                                                          ------------       ------------
STOCKHOLDERS' EQUITY:
    Commonstock, par value $.01 per share, 20,000,000 shares 
          authorized, 6,324,298 and 6,311,451 shares issued
          and outstanding at September 30, 1996 and 
          December 31, 1995, respectively                                       63,243             63,115
    Additional paid-in capital                                              26,668,111         26,609,657
    Accumulated deficit                                                     (1,265,606)        (2,724,433)
    Common stock held in treasury, at cost - 421,000 shares
          at September 30, 1996 and 50,000 shares at December 31, 1995      (2,283,078)          (200,000)
    Shareholder note receivable                                               (296,000)          (296,000)
                                                                          ------------       ------------
          Total stockholders' equity                                        22,886,670         23,452,339
                                                                          ------------       ------------
          TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                      $ 30,131,970       $ 30,455,406
                                                                          ============       ============
</TABLE>

           The accompanying notes to consolidated
            financial statements are an integral
                part of these balance sheets.



<PAGE>


                              DIANON SYSTEMS, INC.
                         CONSOLIDATED INCOME STATEMENTS
                FOR THE THREE MONTH AND NINE MONTH PERIODS ENDED
                           SEPTEMBER 30, 1996 AND 1995
                                   (UNAUDITED)

<TABLE>
<CAPTION>
                                          THREE MONTHS                     NINE MONTHS
                                      ENDED SEPTEMBER 30,             ENDED SEPTEMBER 30,
                                      1996            1995            1996              1995
                                  -----------     -----------      -----------      -----------
<S>                               <C>             <C>              <C>              <C>
NET REVENUES                      $13,863,408     $11,328,790      $39,956,557      $33,195,191

COST OF SALES                       6,799,712       4,949,934       19,419,522       14,587,558
                                  -----------     -----------      -----------      -----------

    Gross Profit                    7,063,696       6,378,856       20,537,035       18,607,633

SELLING, GENERAL AND
    ADMINISTRATIVE EXPENSES         5,222,176       4,598,822       15,891,036       15,014,253

RESEARCH AND DEVELOPMENT
    EXPENSES                          722,157       1,399,874        2,304,239        3,585,935
                                  -----------     -----------      -----------      -----------

    Income from Operations          1,119,363         380,160        2,341,760            7,445

INTEREST INCOME                        50,573          81,734          280,365          181,074

INTEREST EXPENSE                       18,038          32,750           62,779          107,396
                                  -----------     -----------      -----------      -----------
Income Before Provision for
    Income Taxes                    1,151,898         429,144        2,559,346           81,123

PROVISION FOR INCOME TAXES            495,316         185,819        1,100,519           35,126
                                  -----------     -----------      -----------      -----------
    Net Income                    $   656,582     $   243,325      $ 1,458,827      $    45,997
                                  ===========     ===========      ===========      ===========
Weighted Average Shares 
    Outstanding                     6,295,106       5,335,878        6,228,925        5,312,865

Primary and Fully Diluted 
    Earnings Per Share            $      0.10     $      0.05      $      0.23      $      0.01
                                  ===========     ===========      ===========      ===========
</TABLE>

                     The accompanying notes to consolidated
                  financial statements are an integral part of
                                these statements.
<PAGE>

<TABLE>
<CAPTION>

                                               DIANON SYSTEMS, INC.

                                 CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
                FOR THE TWELVE MONTHS ENDED DECEMBER 31, 1995 AND NINE MONTHS ENDED SEPTEMBER 30, 1996
                                                   (UNAUDITED)

                                                                                                   Common
                                                                            Unrealized Foreign     Stock
                                                   Additional               Holdings   Currency    Held in    Shareholder
                                   Common Stock     Paid-in    Accumulated  Gains/     Translation Treasury,     Note
                               Shares     Amount    Capital     Deficit     (Losses)   Adjustment  at Cost    Receivable    Total
                               ------     ------    -------     -------     --------   ----------  -------    ----------    -----

<S>                           <C>         <C>      <C>         <C>          <C>         <C>         <C>      <C>        <C>
BALANCE, December 31, 1994     5,296,879  $52,969  $21,591,942 $(2,831,529) $(90,383) $(58,938)    $  --    $     --    $18,664,061
  Stock options exercised         14,572      146       59,286          --        --        --        --          --         59,432
  Issuance of common stock
    and warrants net of
    issuance costs             1,000,000   10,000    4,976,443          --        --        --        --          --      4,986,443
  Common stock held in treasury       --       --           --          --        --        --    (200,000)       --       (200,000)
  Shareholder note receivable         --       --           --          --        --        --        --       (296,000)   (296,000)
  Stock compensation expense -
    stock options                     --       --      (18,014)         --        --        --        --          --        (18,014)
  Write-off of unrealized
    holding losses                    --       --           --          --    90,383        --         --         --         90,383
  Write-off of foreign currency
    translation adjustment            --       --           --          --        --     58,938        --         --         58,938
  Net Income                          --       --           --     107,096        --        --         --         --        107,096
                               ---------   ------   ----------  ----------   ---------   ------  ----------    --------  ----------
BALANCE, December 31, 1995     6,311,451   63,115   26,609,657  (2,724,433)       --        --     (200,000)   (296,000) 23,452,339

  Stock options exercised         12,847      128       58,454          --        --        --         --         --         58,582
  Common stock held in treasury       --       --           --          --        --        --   (2,083,078)      --     (2,083,078)
  Net Income                          --       --           --   1,458,827        --        --         --         --      1,458,827
                               ---------   ------   ----------  ----------   ---------   ------  ----------    --------  ----------
BALANCE, September 30, 1996    6,324,298   $63,243 $26,668,111  $(1,265,606) $    --     $  --  $(2,283,078) $(296,000) $22,886,670
                               =========   ======= ===========  ===========  =========   ======= =========== ========== ===========

</TABLE>

                     The accompanying notes to consolidated
                  financial statements are an integral part of
                                these statements.

<PAGE>


                              DIANON SYSTEMS, INC.
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
          FOR THE NINE MONTH PERIODS ENDED SEPTEMBER 30, 1996 AND 1995
                                   (UNAUDITED)

<TABLE>
<CAPTION>

                                                                    SEPTEMBER 30,     SEPTEMBER 30,
                                                                         1996              1995
                                                                    -------------     -------------

<S>                                                                  <C>               <C>        
CASH FLOWS FROM OPERATING ACTIVITIES: 
    Net income                                                       $ 1,458,827       $    45,997
Adjustments to reconcile net income to net
    cash provided by (used in) operations -
    Non-cash charges
      Depreciation and amortization                                    1,690,047         2,244,086
      Stock compensation expense                                              --             2,364
      Loss on the sale of fixed assets                                    19,337            17,919
      Investment write-down                                               61,846           365,698
Changes in other current assets
    and liabilities
    (Increase) decrease in accounts receivable                        (2,836,940)        2,375,405
    (Increase) in prepaid expenses
      and employee advances                                             (322,668)         (624,312)
    (Increase) in inventory                                              (79,296)          (26,509)
    (Increase) in other assets                                            (3,788)          (77,703)
    Increase in accounts payable and accrued liabilities                 895,631           589,588
    (Decrease) increase in restructuring reserves                        (11,014)           66,025
                                                                    ------------      ------------
      Net cash provided by operating activities                          871,982         4,978,558
                                                                    ------------      ------------
CASH FLOWS FROM INVESTING ACTIVITIES:
    Capital expenditures                                              (3,315,215)       (1,943,477)
    Proceeds from the sale of stock held for investment                   73,661                --
    Proceeds from the sale of fixed assets                                 7,500             1,500
                                                                    ------------      ------------
      Net cash (used in) investing activities                         (3,234,054)       (1,941,977)
CASH FLOWS FROM FINANCING ACTIVITIES:
    Repayments of note payable                                          (681,790)         (641,841)
    Repayments of capitalized lease obligations                           39,406           (32,990)
    Purchase of common stock held in treasury                         (2,083,078)               --
    Exercise of stock options                                             58,582            59,426
                                                                    ------------      ------------
      Net cash (used in) financing activities                         (2,666,880)         (615,405)
                                                                    ------------      ------------
      Net (decrease) increase in cash and cash equivalents            (5,028,952)        2,421,176
CASH AND CASH EQUIVALENTS,
    beginning of year                                                 10,990,231         3,534,093
                                                                    ------------      ------------
CASH AND CASH EQUIVALENTS, end of period                            $  5,961,279      $  5,955,269
                                                                    ============      ============

Supplemental cash flow disclosures:
    Cash paid during the period:
      Interest                                                      $     63,174      $    107,250
      Income Taxes                                                     1,299,005           581,800

</TABLE>

                     The accompanying notes to consolidated
                  financial statements are an integral part of
                                these statements.


<PAGE>


                              DIANON SYSTEMS, INC.

                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1.  The Company - The  consolidated  balance sheet as of September 30, 1996, the
    related  consolidated  income  statements for the three month and nine month
    periods  ended  September  30,  1996  and  1995,  the  related  consolidated
    statements  of  stockholders'  equity  for the  twelve  month  period  ended
    December  31, 1995 and nine month period  ended  September  30, 1996 and the
    consolidated  statements  of cash  flows for the nine  month  periods  ended
    September 30, 1996 and 1995, have been prepared by DIANON Systems, Inc. (the
    "Company")  without  audit.  In the opinion of management,  all  adjustments
    necessary to present  fairly the financial  position,  results of operations
    and cash flows for such periods have been made.  During the interim  periods
    reported  on,  the  accounting  policies  followed  are in  conformity  with
    generally  accepted  accounting  principles  and are  consistent  with those
    applied for annual  periods and  described in the  Company's  Annual  Report
    filed on Form 10-K with the Securities and Exchange  Commission on March 29,
    1996 (the "Annual Report").

    Certain information and footnote  disclosures normally included in financial
    statements   prepared  in  accordance  with  generally  accepted  accounting
    principles  have been  omitted.  It is  suggested  that  these  consolidated
    financial  statements be read in conjunction  with the financial  statements
    included in the  Company's  Annual  Report for the year ended  December  31,
    1995.  The results of operations  for the three month and nine month periods
    ended  September  30, 1996 and 1995 are not  necessarily  indicative  of the
    operating results for the full year.

2.  Definitions  -  The  descriptive  analysis  contained  herein  compares  the
    financial  results  of the first  nine  months  ended  September  30 and the
    current  three  months ended  September  30 for the years 1996 and 1995.  To
    accommodate the comparison of pertinent financial  information the following
    terms will be used to describe certain aspects of the Company's business:

    "First Nine Months of 1996" - nine months ended September 30, 1996
    "First Nine Months of 1995" - nine months ended September 30, 1995

    "Third Quarter of 1996" - three months ended September 30, 1996
    "Third Quarter of 1995" - three months ended September 30, 1995

    "Clinical  chemistry"  or  "clinical  laboratory"  services  - the  Oncosite
    cancer-related blood test service and the Neocyte  birth-risk-related  blood
    test service.  In general,  these test services are performed by DIANON, and
    the test result is interpreted by the physician who ordered the test.

    "Anatomic  pathology" or "pathology"  services - all other testing  services
    performed by the Company including,  but not limited to, genetic,  molecular
    and  immunohistochemistry  testing services as well as traditional histology
    and morphology evaluations.  In general, these tests are performed by DIANON
    and are interpreted by a physician or other licensed laboratory professional
    employed by DIANON. Some clinical chemistry services associated with certain
    anatomic  pathology  services  are  classified  by the Company as  pathology
    services although they may be regulated and reimbursed as clinical chemistry
    services.

3.  Reclassifications -  Certain  reclassifications  have  been made to the 1995
    amounts to conform to the classifications used in 1996.


<PAGE>

                MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
                       CONDITION AND RESULTS OF OPERATIONS
         THREE MONTHS AND NINE MONTHS ENDED SEPTEMBER 30, 1996 AND 1995
                                   (UNAUDITED)

Results of Operations
- ---------------------

     o   Net Revenues

Net  revenues  were  $40.0  million  during the First  Nine  Months of 1996,  an
increase of $6.8  million or 20% from the First Nine  Months of 1995.  Increased
revenues  in the First Nine  Months of 1996 over the  comparable  period of 1995
were  attributable  to increased  market  penetration by the Company's  anatomic
pathology  testing  services  and were  offset to some  extent by a decrease  in
clinical chemistry and hospital-originated pathology services.

Net revenues were $13.9 million during the Third Quarter of 1996, an increase of
$2.5  million or 22% from the Third  Quarter of 1995.  Increased  revenues  were
attributable to increased market penetration by the Company's anatomic pathology
testing services.

     o   Cost of Sales

Cost of sales,  which  consists  primarily  of  salaries  and wages,  laboratory
supplies,  outside services,  logistics  (primarily shipping and handling),  and
depreciation expense, was $19.4 million during the First Nine Months of 1996, an
increase of $4.8 million or 33% from the First Nine Months of 1995. Salaries and
wages were  approximately  $6.2 million during the First Nine Months of 1996, an
increase  of $2.0  million  or 48% from the  First  Nine  Months  of 1995.  This
increase was  principally due to increased  laboratory and physician  employment
incurred to support new anatomic pathology testing services. Laboratory supplies
were  approximately  $4.1  million  during  the First  Nine  Months of 1996,  an
increase of $499,000  or 14% from the First Nine Months of 1995.  This  increase
was the result of increased  sales volume and increased  costs for reagents used
for some of the Company's testing  services.  Logistics were $3.0 million in the
First Nine  Months of 1996,  an  increase  of $167,000 or 6% from the First Nine
Months of 1995. As a percentage of net revenues,  cost of sales increased to 49%
during  the First Nine  Months of 1996 from 44% during the First Nine  Months of
1995.

Cost of sales was $6.8 million  during the Third Quarter of 1996, an increase of
$1.8  million or 37% from the Third  Quarter  of 1995.  As a  percentage  of net
revenues,  cost of sales  increased to 49% during the Third Quarter of 1996 from
44% during the Third Quarter of 1995.

     o   Gross Profit

Gross  profits  were $20.5  million  during the First  Nine  Months of 1996,  an
increase  of $1.9  million  or 10% from  the  First  Nine  Months  of 1995.  The
Company's gross profit margin decreased to 51% for the First Nine Months of 1996
from 56% for the First Nine Months of 1995.  The decrease in gross profit margin
was due to the  continued  reduction  of the average unit price  reimbursed  for
certain clinical chemistry services and the increased costs necessary to provide
an increased range of anatomic pathology testing services.

Gross profits were $7.1 million during the Third Quarter of 1996, an increase of
$685,000  or 11% from the Third  Quarter of 1995.  The  Company's  gross  profit
margin  decreased  to 51% for the Third  Quarter  of 1996 from 56% for the Third
Quarter of 1995.

The clinical  laboratory  industry has seen steady  downward  pressure on prices
exerted by both government and private  third-party  payers.  Also,  payment for
services such as those provided by the Company is and likely will continue to be
affected by periodic  reevaluations  made by payers concerning which services to
reimburse and which to cease reimbursing.  The reduction in reimbursement rates,
particularly by Medicare,  has generally  decreased the average unit price,  and
thus the average gross profit,  for many of the  Company's  clinical  laboratory
services  each year. In keeping with this trend,  as part of the Omnibus  Budget
Reconciliation Act of 1993 ("OBRA '93"), Congress reduced over time the national
cap  on  Medicare  clinical  laboratory  fee  schedules.   OBRA  '93  was  fully

<PAGE>
implemented in 1996 and has reduced the cap on Medicare clinical  laboratory fee
schedules to 76% of the national  median.  It also eliminated the annual updates
of such fee schedules for the years 1994 and 1995.

With respect to the Company's tissue testing services,  which are not reimbursed
under the Medicare  clinical  laboratory  fee  schedules,  the Medicare fees for
these services also generally  declined with the  implementation of the resource
based relative value scale ("RBRVS") system which went into effect on January 1,
1992. This program was also fully  implemented in 1996 and has had the effect of
reducing  reimbursement  for pathology testing services although not to the same
extent as the Medicare reimbursement reduction for clinical laboratory services.

Any future changes in government and other third-party payer reimbursement which
may come about as a consequence of an enactment of health care reform or deficit
reduction  legislation will also be likely to continue the downward  pressure on
prices and make the markets for all of the Company's  services more competitive.
H.R. 2491, the Balanced Budget Act of 1995, would have made substantial  changes
to the  Medicare  program;  however,  it was  vetoed  by  President  Clinton  in
December, 1995. Nevertheless,  this bill as well as President Clinton's Medicare
counterproposal contained in his fiscal year 1997 budget offer some insight into
future  Medicare  reform  legislation.  H.R. 2491 would have further reduced the
national  cap  on  Medicare  clinical  laboratory  fee  schedules  to 65% of the
national  median in 1997. It also would have  eliminated  annual  updates in the
Medicare clinical laboratory fee schedules until fiscal year 2002. However, H.R.
2491 would have  implemented a new  "conversion  factor" that may have favorably
affected the Company's physician  pathology service  reimbursements by less than
five percent.

Both H.R.  2491 and the  President's  Medicare  proposal  would have revised the
Medicare  program  substantially  to  permit  beneficiaries  to  choose  between
traditional   fee-for-service  Medicare  and  several  non-traditional  Medicare
options, including managed care plans and provider-sponsored organization plans.
These  non-traditional  Medicare  plans would have  considerable  discretion  in
determining whether and how to cover and reimburse all of the Company's services
and to limit the number of laboratories  with which they deal.  Although neither
proposal would have required  Medicare  beneficiaries  to pay 20% of the fee for
each clinical laboratory service, nothing in the proposals would have prohibited
non-traditional Medicare plans from implementing such a requirement.

In addition,  H.R. 2491 proposed  that a fail-safe  budget  mechanism be used if
projected savings were not realized in Medicare laboratory service expenditures.
This fail-safe  mechanism might have further reduced  reimbursement for Medicare
clinical  laboratory  services and physician  services  (including the Company's
pathology  services).  The President's original Medicare  counterproposal  would
have established  competitive  bidding for clinical laboratory services instead.
Although these competitive  bidding provisions were not included in the Medicare
section of  President  Clinton's  fiscal year 1997 budget  proposal,  they could
resurface  in future  Medicare  proposals  if there is a need to  generate  more
savings from the Medicare  program.  Furthermore,  the  President's  support for
competitive  bidding has  rekindled  efforts  within the Health  Care  Financing
Administration ("HCFA") to initiate a Medicare demonstration project to test the
savings  potential  of  competitive  bidding  for  Part  B  clinical  laboratory
services.  If ultimately adopted,  either through federal legislation or through
HCFA  policy,  these  changes  would  have an  adverse  impact on the  Company's
revenues.

Medicare  reform is a major  unpredictable  factor for the  Company's  business.
During  any  budget  reconciliation  process  and if and  when  Medicare  reform
legislation is considered by Congress, the reforms mentioned above or others are
likely to be considered again.  Because of the  uncertainties  about the nature,
content and timing of legislative initiatives and the market's response to them,
the Company currently is unable to predict their ultimate impact on the clinical
laboratory  or  anatomic  pathology  markets  generally  or on  the  Company  in
particular. Even without definitive federal legislative action, however, reforms
are likely to occur at the state level  and/or in response to market  pressures.
In the past the Company has offset a substantial  portion of the impact of price
decreases and coverage changes through the achievement of economies of scale and
other strategies such as more favorable  purchase contracts and the introduction
of alternative technologies.  However,  depending upon whether and how the price
decreases  and other  changes  which could occur as a result of federal or state
legislation are implemented,  they could have an adverse impact on gross profits
from the Company's  testing  services until  management is able to mitigate such
impact; provided,  however, that there can be no assurance that management would
be able to mitigate such impact.  Furthermore,  as a general trend, it should be
expected that gross profit margins will continue to decline over the long term.

<PAGE>

     o   Selling, General and Administrative Expenses

Selling, general and administrative expenses were $15.9 million during the First
Nine Months of 1996,  an increase of $877,000 or 5.8% from the First Nine Months
of 1995. As a percentage of net revenues,  selling,  general and  administrative
expenses  decreased  to 40% for the First  Nine  Months of 1996 from 45% for the
First Nine Months of 1995. Levels of these  expenditures in 1995 were abnormally
elevated as a result of one-time charges for  amortization,  severance costs and
investment write-downs incurred in the First Nine Months of 1995.

Selling,  general and administrative expenses were $5.2 million during the Third
Quarter of 1996,  an increase of $623,000 or 14% from the Third Quarter of 1995.
As a percentage of net revenues,  selling,  general and administrative  expenses
decreased to 38% for the Third Quarter of 1996 from 41% for the Third Quarter of
1995. Levels of these expenditures in 1995 were abnormally  elevated as a result
of one-time charges for amortization and investment  write-downs incurred in the
Third Quarter of 1995.

Amortization  expense,  severance costs,  international  restructuring costs and
investment   write-downs  of  approximately  $2.1  million  previously  reported
separately  in 1995 were  combined  with the  appropriate  selling,  general and
administrative and research and development expenses beginning in 1996.

Amortization  expense was  $206,000 in the First Nine Months of 1996, a decrease
of  $954,000  or 82% from the  First  Nine  Months  of 1995.  This  decrease  is
primarily a result of the Company recording a one-time accelerated  amortization
charge of  approximately  $765,000  during the  second  quarter of 1995 based on
management's  revised  estimate of future benefits  anticipated  from a customer
list.  Amortization  expense was  $69,000  during the Third  Quarter of 1996,  a
decrease of $38,000 or 35% from the Third Quarter of 1995.

Severance  costs were  $148,000 in the First Nine Months of 1996,  a decrease of
$259,000 or 64% from the First Nine Months of 1995. The severance costs were due
primarily to the resignation of officers in 1995 and 1996.  Severance costs were
$102,000  during the Third Quarter of 1996. No similar  charges were recorded in
the Third Quarter of 1995.

Investment write-downs were $62,000 in the First Nine Months of 1996, a decrease
of $304,000 or 83% from the First Nine Months of 1995. This decrease is a result
of the Company  recording  in the First Nine Months of 1995 (and,  other than as
described in the last sentence of this  paragraph,  not in the First Nine Months
of 1996) a  write-down  to market value of the  investment  in common stock of a
publicly  traded company as the loss in value was deemed other than temporary in
accordance with the Statement of Financial  Accounting Standard 115, "Accounting
for Certain Investments on Debt and Equity Securities".  Investment  write-downs
were $50,000 in the Third Quarter of 1996.  The  write-down in the Third Quarter
of 1996 represented the remaining investment in that common stock.

International restructuring costs of approximately $118,000 were recorded in the
First  Nine  Months of 1995  relating  to  anticipated  severance  expenses  and
associated  costs to close-down the Company's  remaining  foreign  branches.  No
similar charges were recorded in the First Nine Months of 1996.

     o   Research and Development

Research and development  expenses were $2.3 million in the First Nine Months of
1996, a decrease of approximately $1.3 million or 36% from the First Nine Months
of 1995.  Research and development  expenses during 1995 were higher than normal
because  they  included  the costs of  developing  the  Company's  new  anatomic
pathology services, building the Company's database and reviewing, analyzing and
clinically evaluating existing as well as new technologies. The decrease in such
expenses  in the  First  Nine  Months  of 1996  was  principally  caused  by the
completion in 1995 of the major portion of such expenditures for the development
of the new anatomic pathology services. It should be expected that such research
and  development  expenses  will  decline  as a  percentage  of sales in 1996 as
compared to 1995.

Research and development  expenses were $722,000 in the Third Quarter of 1996, a
decrease of approximately $678,000 or 48% from the Third Quarter of 1995.

<PAGE>

     o   Interest Income

During the First Nine Months of 1996 interest income was earned on an average of
$5.5 million of cash and cash  equivalents  for the period.  Interest income was
approximately  $280,000  for the First  Nine  Months  of 1996,  an  increase  of
$100,000  or 56% from the First Nine  Months of 1995  which was  caused  both by
higher  interest  rates and by investing  over $4.6 million in net cash proceeds
from a private placement of the Company's  securities completed in October 1995.
Interest  income was  approximately  $51,000  for the Third  Quarter of 1996,  a
decrease of $31,000 or 38% from the Third Quarter of 1995.

     o   Interest Expense

Interest expense was approximately  $63,000 for the First Nine Months of 1996, a
decrease of $45,000 or 42% from the First Nine Months of 1995.  The  decrease in
interest expense was due to the periodic monthly repayments required on the $3.5
million term loan obtained in July of 1993 which bears  interest at 6% per year.
Interest  expense was  approximately  $18,000 for the Third  Quarter of 1996,  a
decrease of $15,000 or 45% from the Third Quarter of 1995.

     o   Provision for Income Taxes

Provision  for income tax expense was $1.1  million for the First Nine Months of
1996, representing an increase of approximately $1.1 million from the First Nine
Months of 1995.  The  effective tax rate was  approximately  43% during both the
First Nine Months of 1996 and 1995.

     o   Net Income

As a result of the  foregoing,  for the First Nine Months of 1996 net income was
$1.5  million,  an increase of  approximately  $1.4  million from the First Nine
Months of 1995.  For the Third  Quarter of 1996,  net income  was  $657,000,  an
increase of approximately $413,000 from the Third Quarter of 1995.

Liquidity and Capital Resources
- -------------------------------

As of September  30, 1996,  the Company had total cash and cash  equivalents  of
approximately  $6 million  which were  invested in U.S.  Treasury  money  market
mutual
funds.

The  Company had working  capital of $14 million at  September  30, 1996 and $17
million  at  December  31,  1995.  The  working  capital  ratio  was 3.0 to 1 at
September  30, 1996  compared to 3.7 to 1 at December 31, 1995.  The decrease in
working  capital is primarily  attributable  to treasury  shares acquired and to
increased capital expenditures in 1996 over 1995.

   
As of September 30, 1996, the Company has purchased 421,000 shares of its common
stock,  for an  aggregate  consideration  of  approximately  $2.3  million.  The
Company's  Board of  Directors  has  authorized  open market  purchases  for the
Employee Stock Purchase Plan  requirements  totaling  300,000 shares and further
additional open market purchases of up to 379,000 shares.
    

Capital  expenditures  during the First Nine  Months of 1996 were  approximately
$3.3  million  compared  to $1.9  million  during the First Nine Months of 1995,
mainly  for  expansion  of  the  Company's  laboratory  facilities  as  well  as
replacements  in the  normal  course of  operations  and  automation  of certain
existing laboratories.

Domestic trade receivables, net, were $12.3 million as of September 30, 1996, an
increase of $2.8 million or 30% from  December  31, 1995.  The increase in trade
receivables  was due to the increase in revenues during the First Nine Months of
1996 over the comparable  period of 1995.  During the Third Quarter of 1996, the
average number of days sales in domestic trade  receivables was approximately 77
days as compared to 72 days for the comparable period of 1995.

<PAGE>

In July 1993,  the Company  obtained a $3.5  million  term loan from a bank that
bears interest at 6% per year. This term loan and accrued  interest is repayable
in 47 monthly installments of approximately $82,000 which commenced in September
1993 plus one  final  payment  in  August  1997  equal to the  remaining  unpaid
principal and  interest.  During 1995,  the term loan  agreement was modified to
revise certain financial covenants, including those with respect to tangible net
worth  and  debt  service  coverage  requirements  and  limitations  on  certain
expenditures.  During the Third  Quarter  of 1996,  there were no changes in the
Company's  existing  debt  agreements.  Under such term loan,  the  Company  has
outstanding  principal in the amount of  approximately  $885,000 as of September
30, 1996.

On October 5, 1995, the Company completed a $5,612,000 private placement with an
investor  for 1 million  shares of common  stock and 800,000  two-year  warrants
exercisable  at $6.00  per  share of  common  stock of the  Company  (except  as
otherwise  described  below).  The Company  received  cash of  $5,316,000  and a
two-year  promissory note for $296,000  bearing 7% interest.  As a result of the
amendment to the warrants  discussed  below,  some or all of the warrants can be
exercised at a price of $5.00 at any time on or before  October 31,  1996.  Upon
such  election the Company  shall  extinguish  as an  adjustment to the purchase
price paid for such warrants,  for each such warrant for which such election has
been  made,  $0.37 of the  principal  amount  of the note  upon  payment  of the
interest due on such  extinguished  amount for the  outstanding  period.  If the
800,000  warrants are all exercised on or before  October 31, 1996, the two year
promissory note for $296,000 will be fully extinguished. On August 20, 1996, the
Company's Board of Directors  approved an amendment to the terms of the warrants
to extend from October 4, 1996 to October 31, 1996,  the date through  which the
warrants  can be  exercised at $5.00 per share.  The  amendment  was approved in
connection  with the scheduling of the Company's  Annual Meeting for October 24,
1996 to enable  voting at such  meeting on a proposal to enable the  investor to
vote shares of the  Company's  common  stock owned by such  investor and certain
affiliates  representing  up to 20% of the total voting  power of the  Company's
voting  securities  outstanding  from time to time to be completed  prior to the
expiration of the $5.00 per share exercise price.  Such proposal was approved at
the  Company's  Annual  Meeting on October 24, 1996.  On October 29,  1996,  the
investor  exercised  all 800,000  warrants  and in  exchange  for the payment of
approximately  $4.0 million in cash representing the aggregate exercise price of
such  warrants and interest on the principal  amount of the two-year  promissory
note for the  outstanding  period,  the Company  issued to the investor  800,000
shares of its common stock and fully  extinguished  and cancelled the promissory
note.

The Company believes that cash flows from operations and available cash and cash
equivalents  are adequate to fund the Company's  operations for the  foreseeable
future.

Risk Factors; Forward Looking Statements
- ----------------------------------------

The  Management's  Discussion and Analysis  contain  forward-looking  statements
regarding the  Company's  future plans,  objectives,  and expected  performance.
These  statements  are  based on  assumptions  that  the  Company  believes  are
reasonable,  but are subject to a wide range of risks and  uncertainties,  and a
number of factors could cause the Company's actual results to differ  materially
from those expressed in the forward-looking  statements referred to above. These
factors include,  among others,  the  uncertainties  in reimbursement  rates and
reimbursement  coverage of various tests sold by the Company to beneficiaries of
the Medicare program;  the uncertainties  relating to the ability of the Company
to convince physicians and/or managed care organizations to use the Company as a
provider of anatomic  pathology testing services;  the ability of the Company to
maintain  superior  quality  relative  to its  competitors;  the  ability of the
Company to maintain  its  hospital-based  business  in light of the  competitive
pressures  and  changes   occurring  in  hospital  health  care  delivery;   the
uncertainties  relating  to  states  erecting  barriers  to the  performance  of
anatomic  pathology  testing by  out-of-state  laboratories;  the ability of the
Company to find,  attract  and retain  above  average  medical,  management  and
technical  personnel;  the uncertainties  associated with competitive  pressures
from the large national  laboratories,  small specialized  laboratories and well
established  local  pathologists;  and the  uncertainties  which  would arise if
integrated  delivery systems closed to outside providers emerged as the dominant
form of health care delivery.

<PAGE>

PART II  OTHER INFORMATION


Item 5   Other Information
         -----------------

         In April 1996, the Company  adopted the 1996 Stock  Incentive Plan (the
         "Plan").  The Plan authorizes  700,000 shares,  of which 630,000 may be
         issued to employees and 70,000 may be issued to outside Directors.  The
         Plan was approved at the Company's Annual Meeting on October 24, 1996.

         The Company entered into executive  employment  agreements with Richard
         A.  Sandberg  and  with Dr.  James B.  Amberson  (the  "Employees")  on
         September 1, 1996. Each such agreement  provides that in the event of a
         "Change in Control of the Company",  as defined in the  agreements,  if
         the  Employee's  employment  is terminated  other than for "Cause",  as
         defined in the agreements,  he is entitled to receive one year's salary
         and  bonus  and  all  his  stock  options  will  vest  completely.  The
         agreements  expire in  September  2001 and are  subject  to  successive
         automatic  one-year  renewals  thereafter  (unless  certain  notice  is
         given). The employment  agreements are filed herewith as exhibits 10.38
         and 10.39.

         The Company has also entered into a employment agreement with Dr. James
         B.  Amberson  on  September  1, 1996.  Pursuant to the  agreement,  Dr.
         Amberson is entitled to a salary as determined by the Company and other
         benefits of the Company. This agreement provides that in the event of a
         termination of Dr. Amberson's  employment for other than "Stated Cause"
         (as  defined in the  agreement),  he is  entitled to receive six months
         salary and other benefits.  Subject to the foregoing, this agreement is
         subject  to  termination  at  will  by  either  party.  The  employment
         agreement is filed herewith as exhibit 10.40.

         The  Company  entered  into  an  employment  agreement  with  David  R.
         Schreiber  on  September  30, 1996 as the Chief  Financial  Officer and
         Senior  Vice  President,  Finance  of the  Company.  Salary  and  other
         compensation  are disclosed in the employment  agreement filed herewith
         as exhibit 10.42.

Item 6   Exhibits and Reports on Form 8-K
         --------------------------------

     a   Exhibits

         10.38    Employment   Agreement,   dated  September  1,  1996,  by  the
                  registrant and Richard A. Sandberg.

         10.39    Employment   Agreement,   dated  September  1,  1996,  by  the
                  registrant and Dr. James B. Amberson.

         10.40    Employment   Agreement,   dated  September  1,  1996,  by  the
                  registrant and Dr. James B. Amberson.

         10.41    Severance   Agreement,   dated  September  27,  1996,  by  the
                  registrant and Carl R. Iberger.

         10.42    Employment  Agreement,   dated  September  30,  1996,  by  the
                  registrant and David R. Schreiber.

         11.1     Statement  regarding computation  of per share earnings is not
                  required  because the relevant  computation  can be determined
                  from  the  material  contained  in  the  Financial  Statements
                  included herein.

         27.1     Financial Data Schedule.

     b   Reports on Form 8-K

         No reports on Form 8-K were filed  during the quarter  ended  September
         30, 1996.

<PAGE>

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


                                            DIANON SYSTEMS, INC.




   
                    November 15, 1996       /s/ Kevin C. Johnson
                                            -------------------------------  
                                            By: Kevin C. Johnson
                                            President and
                                            Principal Executive Officer



                    November 15, 1996       /s/ Richard A. Sandberg
                                            -------------------------------
                                            By: Richard A. Sandberg
                                                Chairman,
                                                Principal Financial Officer and
                                                Principal Accounting Officer
    


<PAGE>

                                  EXHIBIT INDEX
<TABLE>
<CAPTION>
                                                                          Page
                                                                          ----
<S>     <C>                                                                <C>
10.38   Employment Agreement, dated September 1, 1996,                     16
        by the registrant and Richard A. Sandberg                          
        (filed herewith).                                                  

10.39   Employment Agreement, dated September 1, 1996,                     23
        by the registrant and Dr. James B. Amberson           
        (filed herewith).                                                  

10.40   Employment Agreement, dated September 1, 1996,
        by the registrant and Dr. James B. Amberson           
        (filed herewith).                                                  38

10.41   Severance Agreement, dated September 27, 1996,
        by the registrant and Carl R. Iberger 
        (filed herewith).                                                  45

10.42   Employment Agreement, dated September 30, 1996,
        by the registrant and David R. Schreiber
        (filed herewith).                                                  50

27.1    Financial Data Schedule (filed herewith).                          69

</TABLE>


                         EXECUTIVE EMPLOYMENT AGREEMENT


              AGREEMENT,  dated as of 9/1/96,  by and  between  DIANON  Systems,
Inc., a Delaware corporation having offices at 200 Watson Boulevard,  Stratford,
Connecticut 06497 (the "Company"),  and Richard A. Sandberg,  whose residence is
233 Brushy Ridge Road, New Canaan, Connecticut 06840 (the "Executive").

              The  Company's  Board of Directors  (the  "Board")  considers  the
continued  services of key  executives of the Company to be in the best interest
of the Company and its stockholders.

              The  Board  desires  to  assure,  and  has  determined  that it is
appropriate  and in the best  interests of the Company and its  stockholders  to
reinforce  and  encourage,   the  continued  attention  and  dedication  of  key
executives  of the Company to their  duties  with-out  personal  distraction  or
conflict of interest in circumstances arising from the possibility or occurrence
of a change in control of the Company.

              In  consideration of the premises and the covenants and agreements
con-tained  herein, and other good and valuable  consideration,  the Company and
the Executive agree as follows:

         1. Services During Certain  Events.  In the event a proposal is made to
effect a Change in Control  (as  defined in  Section 3  hereof),  the  Executive
agrees  that he will not  voluntarily  leave the employ of the  Company and will
render the services  contemplated  in the recitals of this Agreement  until such
proposal for a Change in Control is terminated or abandoned or until a Change in
Control has occurred, except as otherwise provided in Section 2 hereof.

         2. Termination.  For purposes of this Agreement,  a "Termination" shall
be deemed to have occurred in the event that the  Executive's  employment by the
Company is  terminated  at any time from 90 days prior to a Change in Control to
two years following a Change in Control:

              (a) by the Company for reasons  other than  "cause" (as defined in
Section 6 hereof),  "disability"  (as  defined  in  Section 6 hereof),  death or
attainment of age 65;

              (b)  by  the  Executive  following  the  occurrence  of any of the
following events without the Executive's consent:

                     (i) the   assignment  of  the  Executive  to  any duties or
         responsibilities  that  are  inconsistent  with his  position,  duties,
         responsibilities  or  status  immediately   preceding  such  Change  in
         Control, or a change in his reporting responsibilities or titles within
         the  Company in effect at such time  resulting  in a  reduction  of his
         responsibilities or position at the Company;
 
                    (ii) a reduction of the Executive's annual salary;

                   (iii) a  material  reduction  in  any  year of the  ratio  of
         incentive  compensation  or  fringe benefits  received by the Executive
         pursuant to any bonus,  incentive or fringe  benefit plan (the "Benefit
         Plan") to his annual  salary in such year,  which  reduction is greater
         than the average reduction in the ratio of such incentive  compensation

<PAGE>
         or fringe benefits to annual salary received by all participants  under
         the Benefits Plans;

                    (iv) a material  increase  in the  amount of travel normally
         required of the  Executive in  connection  with his  employment  by the
         Company,  or the transfer of the  Executive  to a location  requiring a
         change in his residence; or

                     (v) any  failure by the  Company to comply with and satisfy
         Section 8 of this Agreement; or

              (c) by the Executive,  if he determines,  in his sole  discretion,
during the 60-day period commencing 180 days following a Change in Control, that
due to the Change in Control he can no longer  effectively  perform  his duties.
For purposes of this Agreement,  any determination by the Executive  pursuant to
the preceding sentence shall be conclusive.

         3. Change in Control.  For  purposes  of this  Agreement,  a "Change in
Control" of the Company shall be deemed to have occurred if:

              (a) individuals who, as of the date hereof,  constitute the entire
Board of  Directors  of the Company (the  "Incumbent  Directors")  cease for any
reason to constitute at least a majority of the Board,  provided,  however, that
any  individual  becoming a director  subsequent  to the date of this  Agreement
whose election,  or nomination for election by the Company's  shareholders,  was
approved  by a vote of at  least a  majority  of the then  In-cumbent  Directors
(other than an election or  nomination  of an  individual  whose  assumption  of
office is the result of an actual or threatened election contest relating to the
election  of  directors  of the  Company,  as such terms are used in Rule 14a-11
under the  Securities  Exchange Act of 1934, as amended (the  "Exchange  Act")),
shall be, for purposes of this  Agreement,  considered as though such individual
were an Incumbent Director; or

              (b)  the  shareholders  of  the  Company  shall  approve  (i)  any
consolidation  or  recapitalization  of the Company (or, if the capital stock of
the Company is affected,  any subsidiary of the Company) or any sale,  lease, or
other transfer (in one transaction or a series of  transactions  contemplated or
arranged  by any  party as a single  plan)  of all or  substantially  all of the
assets of the Company (each of the foregoing being an "Acquisition Transaction")
where (x) the shareholders of the Company  immediately prior to such Acquisition
Transaction   would  not   immediately   after  such   Acquisition   Transaction
beneficially own, directly or indirectly,  shares  representing in the aggregate
more  than  65% of (A) the then  outstanding  common  stock  of the  corporation
surviving or resulting from such merger,  consolidation or  recapitalization  or
acquiring  such  assets  of the  Company,  as the  case  may be (the  "Surviving
Corporation")  (or of its  ultimate  parent  corporation,  if  any)  and (B) the
Combined  Voting  Power  (as  defined  below)  of the  then  outstanding  Voting
Securities (as defined below) of the Surviving  Corporation  (or of its ultimate
parent  corporation,  if any) or (y) the Incumbent  Directors at the time of the
initial approval of such  Acquisition  Transaction  would not immediately  after
such Acquisition  Transaction constitute a majority of the Board of Directors of
the Surviving  Corporation  (or of its ultimate parent  corporation,  if any) or
(ii) any plan or proposal for the liquidation or dissolution of the Company; or

              (c) any Person (as  defined  below)  shall  become the  beneficial
owner (as defined in Rules 13d-3 and 13d-5 under the Exchange Act),  directly or
indirectly,  of securities of the Company  representing  in the aggregate 30% or
more of either  (i) the then  outstanding  shares of the  Company  Common  Stock

<PAGE>
("Common  Stock"),  or (ii) the Combined  Voting  Power of all then  outstanding
Voting Securities of the Company;  provided,  however, that notwithstanding the
foregoing,  a Change  in  Control  of the  Company  shall  not be deemed to have
occurred for purposes of this subsection (c) solely as the result of:

                    (i) the acquisition of securities by the Company  which,  by
         reducing  the  number  of  shares  of  Common  Stock  or  other  Voting
         Securities  outstanding,  increases  (i) the  proportionate  number  of
         shares of Common Stock  beneficially owned by any Person to 30% or more
         of  the  shares  of  Common  Stock  then   out-standing   or  (ii)  the
         proportionate   voting  power  represented  by  the  Voting  Securities
         beneficially  owned by any Person to 30% or more of the Combined Voting
         Power of all then outstanding Voting Securities; or

                   (ii) an acquisition of securities if the Incumbent  Directors
         at the time of the  initial  approval  of such  acquisition  would  not
         immediately  after  (or  otherwise  as a result  of)  such  acquisition
         constitute a majority of the Board;

                        (A)  any conversion  of a security that was not acquired
              directly from the Company; or

                        (B)  any  acquisition  of  securities  if the  Incumbent
              Directors at the time of the initial  approval of such acquisition
              would not  immediately  after (or  otherwise  as a result of) such
              acquisition constitute a majority of the Board;

provided,  however, that if any Person referred to in subsections (i) or (ii) of
this clause (c) shall  thereafter  become the beneficial owner of any additional
shares of the Company  Common  Stock or other Voting  Securities  of the Company
(other than pursuant to a stock split, stock dividend or similar  transaction or
an  acquisition  exempt under such  subsection  (ii)),  then a Change in Control
shall be deemed to have occurred for purposes of this clause(c).

              (d)  Notwithstanding  anything  contained in this Agreement to the
contrary,  if the  Executive  experiences  a  Termination  prior to a Change  in
Control and the Executive reasonably  demonstrates that such Termination (A) was
at the request of a Third Party (as defined below) or (B) otherwise  occurred in
connection with or in anticipation of a Change in Control, then for all purposes
of the  Agreement,  the  date of such  Change  in  Control  shall  mean the date
immediately prior to the date of such Termination.

              For purposes of this Agreement:

              "Person" shall mean any  individual,  entity  (including,  without
limitation, any corporation,  partnership,  trust, joint venture, association or
governmental  body and any successor to any such entity) or group (as defined in
Sections  13(d)(3) or 14(d)(2) of the Exchange Act and the rules and regulations
thereunder); provided, however, that Person shall not include the Executive, the
Company, any of its majority-owned  subsidiaries,  any executive benefit plan of
the Company or any of its  majority-owned  subsidiaries or any entity organized,
appointed  or  established  by  the  Executive,   the  Company  or  any  of  its
majority-owned  subsidiaries  for or pursuant to the terms of any such plan,  or
any of their affiliates;

<PAGE>
              "Voting  Securities"  shall mean all  securities  of a corporation
having the right  under  ordinary  circumstances  to vote in an  election of the
board of directors of such corporation;

              "Combined Voting Power" shall mean the aggregate votes entitled to
be case  generally in the election of directors of a  corporation  by holders of
then outstanding Voting Securities of such corporation; and

              "Third  Person"  shall  mean a third  party who has  indicated  an
intention, or taken steps reasonably calculated, to effect a Change in Control.

         4. Rights and Benefits upon Termination or Change in Control.

              (a) Severance  Payment.  Subject to Section 6 and 11(a) hereof, in
the event of a Termination the Company shall pay the Executive,  in twelve equal
monthly  installments  beginning no later than 30 days following the Executive's
Termination,  (i) the  greater  of the  Executive's  annual  salary as in effect
immediately  prior to (x) the  Termination or (y) a  Change in Control plus (ii)
if a Change of Control  could  have been  deemed to occur as a result of meeting
the  conditions  set  forth  in  paragraph  3(a)  hereof  (whether  or not  such
conditions were the sole reason for a Change of Control), the most recent annual
bonus paid the Executive.  In the event of the Executive's  death, such payments
shall be made to Executive's estate or other legal representative.

              (b) Stock Options.  Immediately prior to a Change in Control,  all
out-standing  options to buy  Company  stock held by the  Executive,  other than
options granted  pursuant to the Company's  Employee Stock Purchase Plan,  shall
become fully vested and immediately exercisable.

              (c) Restricted  Stock.  Immediately  prior to a Change in Control,
any (i) repurchase  agreement or (ii) right of first refusal  agreement  between
the Executive and the Company with respect to the Company stock shall  terminate
and the Executive's ownership of all shares of Company stock shall fully vest.

         5.  Certain  Additional  Payments  by the  Company.  Anything  in  this
Agreement to the contrary  notwithstanding,  in the event it shall be determined
that  any  payment,  distribution  or other  action by the Company to or for the
benefit of the  Executive,  whether  pursuant to the terms of this  Agreement or
otherwise (a  "Payment"),  would be subject to the excise tax imposed by Section
4999 of the Internal  Revenue Code or any interest or penalties  with respect to
such excise tax (such excise tax, together with any such interest and penalties,
are  hereinafter  collectively  referred  to as  the  "Excise  Tax"),  then  the
Executive,  if such Executive has been employed by the Company for five years or
more,  shall be entitled to receive from the Company at the time such Excise Tax
is due an  additional  payment (a "Gross-Up  Payment") in any amount  reasonably
calculated by the Company's  independent auditors such that after payment by the
Executive of all taxes (including any interest or penalties imposed with respect
to such taxes), including any Excise Tax, imposed upon the Gross-Up Payment, the
Executive  retains  an amount of the  Gross-Up  Payment  equal to the Excise Tax
imposed upon the Payments.

         6.  Conditions  to the  Obligations  of the  Company.  The  rights  and
benefits  provided in Section 4 hereof shall not accrue to the  Executive if any
of the following events shall occur:

<PAGE>
              (a) The Company shall  terminate the  Executive's  employment  for
"cause." For purposes of this  Agreement,  termination of employment for "cause"
shall mean (i) the Executive's  conviction for, or plea of nolo contendere to, a
felony, (ii) the Executive's engaging in fraud,  misappropriation,  embezzlement
or other act or acts of  dishonesty  resulting  in, or  intended  to result  in,
substantial  personal  enrichment of the Executive at the expense of the Company
or (iii) the Executive's  intentional  and continual  failure  substantially  to
perform  his duties with the Company  (other than a failure  resulting  from the
Executive's  incapacity  due to physical or mental  illness)  which  failure has
continued for a period of at least 30 days after a written  notice of demand for
substantial  performance  has been  delivered  to the  Executive  specifying  in
reasonable  detail the manner in which the Executive has failed to substantially
perform.  Notwithstanding  the foregoing,  the Executive  shall not be deemed to
have been  terminated for cause unless and until there shall have been delivered
to the Executive a copy of a resolution  (x) duly adopted by  three-quarters  of
the  entire  membership  of the  Board,  at a meeting  called  and held for such
purpose  after  reasonable  notice  to  Executive  and an  opportunity  for  the
Executive,  together with the Executive's counsel, to be heard before the Board,
and (y)  finding  that in the good faith  opinion of the  Board,  Executive  was
guilty of  conduct  described  in the  preceding  sentence  and  specifying  the
particulars of such conduct in detail.

              (b)  Following  a  Termination,  the  Executive  shall  not,  upon
receiving a written request to do so, resign as a director and/or officer of the
Company and of each  subsidiary and affiliate of the Company of which he is then
serving as a director and/or officer.

              (c) The Company shall  terminate the  Executive's  employment  for
"disability." For purposes of this Agreement, "disability" shall mean a physical
or psychological  condition of the Executive which renders him unable to perform
his duties for the Company for a period for six months or longer,  as  confirmed
in writing by the Executive's independent physician.

         7. Arbitration and Expenses.

              (a) Any dispute or controversy arising under or in connection with
this  Agreement  shall be settled by  arbitration,  conducted  before a panel of
three arbitrators in Stamford,  Connecticut, in accordance with the rules of the
American  Arbitration  Association  then in  effect.  The  arbitrators  shall be
approved by both the  Company  and the  Executive  and their  decision  shall be
binding on the parties and conclusive for all purposes.  Judgment may be entered
on the arbitrators' award in any court having jurisdiction.  The expense of such
arbitration shall be borne by the Company.

              (b) The Company shall pay or reimburse the Executive for all costs
and  expenses  (including,  without  limitation,   reasonable  attorneys'  fees)
incurred  by the  Executive  as a result  of any  claim,  action  or  proceeding
(including,  without limitation,  a claim, action or proceeding by the Executive
against the Company)  arising out of, or challenging the validity,  advisability
or enforceability of, this Agreement or any provision hereof.

         8. Successors.  The Company shall require any successor (whether direct
or  indirect,  by  purchase,  merger,  consolidation  or  otherwise)  to  all or
substantially all of the business or assets of the Company, by agreement in form
and  substance  satisfactory  to  the  Executive,   expressly,   absolutely  and
unconditionally to assume and agree to perform this Agreement in the same manner

<PAGE>
and to the same extent  that the  Company  would be required to perform it if no
such succession had taken place. As used herein, "the Company" shall include any
successor to all or substantially all of the Company's  business or assets which
executes  and  delivers an  agreement  provided  for in this  Section 8 or which
otherwise  becomes bound by all the terms and  provisions  of this  Agreement by
operation of law.

         9. Notice of Termination. Any termination of the Executive's employment
by the Company shall be  communicated  to the Executive at the address set forth
above (or such other address as the Executive shall have notified the Company in
writing for  purposes of this  Agreement)  in a written  notice and,  except for
termination for "cause," shall specify a termination date no sooner than 15 days
after the giving of such notice.

         10. Term of  Agreement.  This  Agreement  shall  terminate on the fifth
anniversary of the date hereof;  provided,  however,  that this Agreement  shall
automatically  renew for successive one-year terms unless the Company's Board of
Directors  notifies  the  Executive  in  writing  at least  30 days  prior to an
expiration  date that it does not wish to renew the  Agreement for an additional
term; and provided further that if a Change in Control occurs during the term of
an additional term of this Agreement, the Agreement shall continue in effect for
two years following such Change in Control.

         11. Miscellaneous.

              (a) Duty to Mitigate:  Other Severance Payments.  If a Termination
is deemed to occur, the Executive shall during the one-year period subsequent to
his  Termination  notify the Company of any employment  when  obtained,  and the
severance  payment  provided  under  Section  4(a) hereof shall be offset by any
compensation,  which he receives from such employment during the one-year period
subsequent to this  Termination.  Furthermore,  the severance  payment  provided
under  Section 4(a) hereof shall also be offset by any other  severance  payment
which the Executive  receives under any  employment  agreement with the Company,
including damages for breach of any such agreement.

              (b) Assignment.  No right,  benefit or interest hereunder shall be
subject to assignment,  anticipation,  alienation,  sale,  encumbrance,  charge,
pledge, hypothecation or set-off in respect of any claim, debt or obligation, or
to execution,  attachment,  levy or similar process; provided, however, that the
Executive may assign any right, benefit or interest hereunder if such assignment
is  permitted  under the terms of any plan or policy  of  insurance  or  annuity
contract governing such right, benefit or interest.

              (c) Construction of Agreement.  Nothing in this Agreement shall be
construed  to amend any  provision  of any plan or policy of the  Company.  This
Agreement is not, and nothing herein shall be deemed to create,  a commitment of
continued employment of the Executive by the Company.

              (d)  Amendment.  This  agreement  may not be amended,  modified or
canceled except by written agreement of the parties.

              (e) Waiver. No provision of this Agreement may be waived except by
a writing signed by the party to be bound thereby.

              (f)  Severability.  In the event that any  provision or portion of
this  Agreement  shall be  determined  to be  invalid or  unenforceable  for any
reason,  the remaining  provisions of this Agreement  shall remain in full force
and effect to the fullest extent permitted by law.

<PAGE>
              (g) Taxes.  Any payment or delivery  required under this Agreement
shall be subject to all  requirements  of the law with regard to  withholding of
taxes,  filing,  making of reports and the like,  and the Company  shall use its
best efforts to satisfy promptly all such requirements.

              (h) Governing Law. This Agreement  shall be governed and construed
in accordance with the laws of the State of New York.

              (i)  Entire  Agreement.  This  Agreement  sets  forth  the  entire
agreement and  understanding  of the parties  hereto with respect to the matters
covered hereby.


                                            DIANON SYSTEMS, INC.


                                            By:  /s/ Kevin C. Johnson
                                               -------------------------


                                            /s/ Richard A. Sandberg
                                            ----------------------------
                                            Richard A. Sandberg





                              EMPLOYMENT AGREEMENT


         This AGREEMENT made effective September 1, 1996 between Dianon Systems,
Inc., a Connecticut corporation, and any successor thereto, hereinafter referred
to  as  the  "Company,"  and  James  B.  Amberson,  M.D.,  residing  in  Weston,
Connecticut, hereinafter referred to as "Employee."

                                   WITNESSETH:

         WHEREAS,  the Company  wishes to reinforce the capacity of Employee,  a
senior  management  official of the  Company,  to  implement  the  policies  and
programs  established  by the Company,  and to provide for the protection of the
goodwill,  confidential information, and proprietary rights and interests of the
Company,  in each case on the  terms and  subject  to the  conditions  set forth
below; and

         WHEREAS,  Employee's business contacts and relationships are crucial to
the  financial  and  business  success of the  Company,  and the  services  that
Employee should render hereunder to the Company are unique and valuable; and

         WHEREAS,  the  parties  desire to reduce  the terms and  conditions  of
Employee's employment to writing;

<PAGE>
         NOW,  THEREFORE,  in  consideration of the terms and conditions and the
mutual  covenants  contained in this Agreement,  the Company and Employee hereby
agree as follows:

         1.   Employment
              ----------

              The Company  hereby employs  Employee and Employee  hereby accepts
such employment upon the terms and conditions hereinafter set forth. The parties
acknowledge  that  Employee's  employment  with  the  Company  is  at  will  and
terminable by either party at any time for any reason.

         2.   Duties and Responsibilities
              ---------------------------

              Employee shall perform with continuous  diligence those activities
assigned  to  Employee  by  the  Company  including:   active  participation  in
laboratory  and  market  research,  keeping  full and  complete  records  of all
business and/or research  activities in which Employee  engages and surrendering
all such records and materials on request,  improving  strategies  for achieving
the Company's goals,  motivating co-worker  performance,  keeping abreast of all

<PAGE>
new  developments  in Employee's  area of expertise,  participating  actively in
research and business meetings, and abiding by all Company policies.

         3.   Term
              ----

              This  Agreement  shall  begin on the  effective  date  hereof  and
continue until terminated under the terms contained herein.

         4.   Salary
              ------

              The Company  shall  compensate  Employee for  Employee's  services
during the term of this  Agreement on a salaried  basis paid bi-weekly at a rate
determined by the Company from time to time.

         5.   Fringe Benefits
              ---------------

              During the term of this Agreement,  Company shall provide Employee
all benefits and emoluments as authorized  for all other  salaried  employees of
the Company as they may be modified from time to time by the Company  during the

<PAGE>
term of this  Agreement,  including  health and  medical  insurance,  disability
insurance,  life insurance,  sick leave, vacation,  holidays and retirement plan
participation.

         6.   Termination
              -----------

              a. This   Agreement  shall  terminate  on  any  of  the  following
occurrences:

                  (i)  Employee's death;

                  (ii) Employee's disability for a period of 90 days or more;

                  (iii) mutual  agreement  of  the  parties  reduced  to writing
                        signed by both parties;

                  (iv)  voluntary resignation by Employee;

                  (v)   termination by the Company without Stated Cause;

                  (vi)  termination by the Company with Stated Cause.

              b. Cause shall mean Employee's

                  (i)   gross negligence;

                  (ii)  insubordination;

                  (iii) willful misconduct.

              c. "Stated Cause" shall mean Cause communicated to Employee by the
Company in a Notice of Termination.

<PAGE>
              d. "Notice of  Termination"  shall mean  written  notice given  by
either party to the other of an intention to terminate this  Agreement  pursuant
to subparagraphs (a)(iv), (v) or (vi) of this Paragraph of this Agreement.

              e. Notice  of  Termination  shall  be  sent by  certified  mail or
registered mail, return receipt requested,  first class postage prepaid,  to the
residence in the case of Employee,  and to its  principal  office in the City of
Stratford,  Connecticut,  to the  attention of the  President in the case of the
Company.

         7.   Compensation after Termination
              ------------------------------

              (a) The  "Termination  Date"  shall  be the date  Employee  ceases
providing services to the Company as an employee. In the event Employee provides
Notice of Termination to the Company less than four weeks prior to the date such
Notice  identifies  as the  Termination  Date,  then the  date  said  Notice  of
Termination is received by the Company shall be the Termination Date.

              (b) Employee  will not receive any  compensation  from the Company
after the  Termination  Date  other than  accrued,  unused  vacation,  except as
described under  Paragraphs (c) and (d) of this Section 7 of this Agreement,  if

<PAGE>
applicable.  Employee's  participation  in all  fringe  benefits  offered by the
Company to its employees will cease  immediately on the Termination  Date except
as  described  in  Paragraph  (c)  of  this  Section  7 of  this  Agreement,  if
applicable. Nothing in this Agreement, however, is intended to impair any rights
vested under law in any benefit plan of the Company.

              (c) If this Agreement and Employee's  employment  with the Company
is  terminated  by the  Company  without  stated  cause,  the  Company  will pay
Employee:

                   (i)  For  a  period  of  six   months   beginning   with  the
                        Termination Date at Employee's current rate of pay as of
                        the day preceding  the  Termination  Date,  less amounts
                        equivalent  to income  Employee  earns  during  said six
                        month  period  from  other   employment  or  independent
                        consulting.

                   (ii) During said six month  period,  Employee  shall act as a
                        consultant  to the Company as  requested  by the Company
                        for up to six days per month.

                   (iii)During  said  six  month   period,   the  Company   will
                        contribute   towards   the   premium   cost  of  medical
                        continuation  coverage  for Employee  and/or  Employee's
                        dependents  on the  same  basis  as it then  contributes
                        towards the medical  coverage of active employees and/or
                        their  dependents,  for any months in said period during
                        which Employee and/or Employee's dependents are eligible
                        and elect to continue such coverage.

                   (iii)During said six month period,  the Company will continue
                        to  provide  Employee  any car  allowance  Employee  was
                        receiving at the time of the Termination Date.

<PAGE>
              (d) Employee's  participation  in all incentive  plans,  including
bonus and commission,  stock options, restrictive stock purchase plans and other
incentive  compensation programs will terminate on the Termination Date. If this
Agreement terminates (i) by Employee's voluntary  resignation with at least four
weeks'  notice to the  Company or (ii) by  termination  by the  Company  without
Stated  Cause,  the Company will make its best efforts to allocate on a pro rata
basis  based  upon the  number of days from  January 1 to the  Termination  Date
divided by 365, a portion of each such incentive  award to be paid or awarded to
Employee or his estate at the time  payment or awards under any such program are
made to active  employees for the year or other related time period in which the
Termination Date falls.

         8.   Company Property
              ----------------

              On the  Termination  Date, or at any earlier point in time after a
Notice of  Termination  is  received  when a request is made by the  Company for
same,  Employee  will turn over to the  Company all notes,  reports,  memoranda,
books,  records,   chemicals,   devices  and  documents,   whether  in  written,
typewritten,  computerized or any other form, which are in Employee's possession
or under Employee's control,  whether prepared by Employee or others, related to
the Company or relating to the business of the Company. At the conclusion of the
six month period  described in paragraph (c) of Section 6 of this Agreement,  or

<PAGE>
at any  earlier  point in time when a request is made by the  Company  for same,
Employee shall also return to the Company any Company car,  keys,  parking card,
credit card, business cards or other materials related to Employee's  employment
with the Company or the operation of the Company.

         9.   Remedy for Breach
              -----------------

              Employee acknowledges:

                   (a)  that  Employee  may be a  director  and  officer  of the
                        Company and as such Employee  would be conversant  with,
                        and have access to, the business affairs, records, trade
                        secrets,   customers  and  customer  lists,   suppliers,
                        supplier lists, patents, technical know-how,  chemicals,
                        devices,    sales    or    distribution    agents    and
                        representatives,   sales  or  distribution   agents  and
                        representatives'   lists,  and  other  confidential  and
                        proprietary information of the Company;

<PAGE>
                   (b)  that  Employee's   compliance  with  the  covenants  and
                        agreements in this Agreement is necessary to protect the
                        goodwill and other proprietary  interest of the Company;
                        and

                   (c)  that a breach of Employee's  covenants and agreements in
                        this Agreement will result in continuing and irreparable
                        damage  to  the  Company  for  which  there  will  be no
                        adequate remedy at law.

              Both the parties  recognize that the services to be rendered under
this  Agreement  by  Employee  are  special  and unique and of an  extraordinary
character,  and that in the event there is a breach by Employee of the terms and
conditions of this Agreement to be performed by Employee, then the Company shall
be entitled,  if it so elects,  to institute  and prosecute  proceedings  in any
court of competent  jurisdiction  either in law or in equity,  to obtain damages
for any breach of this Agreement, or to enforce the specific performance thereof
by Employee.

<PAGE>
         10.  Employee Representation
              -----------------------

              Employee  warrants and  represents  that neither the execution and
delivery  nor the  performance  of this  Agreement  by Employee  will in any way
violate, or conflict with, any other agreement by which Employee may be bound or
any duty or obligation  to which  Employee may be subject and that Employee will
take all steps necessary to comply with the representation.

         11.  Proprietary Information
              -----------------------

              Employee  hereby  agrees to all the terms  and  conditions  of the
Company's Employee Proprietary  Information Agreement attached hereto as Exhibit
A and incorporated herein and has executed a copy thereof concurrently with this
Agreement.

         12.  Assignments
              -----------

              The rights and  obligations of Employee under this Agreement shall
be  assignable  to and binding  upon the  successors  and assigns of the Company
including any  corporation  organized by the Company to carry on the business of
the Company.

<PAGE>
         13.  Entire Agreement
              ----------------

              This instrument  contains the entire Agreement of the parties.  It
may not be changed orally,  but only by agreement in writing signed by the party
against  whom  enforcement  of any waiver,  change,  modification,  extension or
discharge  is  sought.   This  Agreement   supersedes  any  other  agreement  or
understanding  existing  between  Employee  and  the  Company  relating  to  his
employment or the other matters covered herein.

         14.  Severability
              ------------

              If any provision of this  Agreement  shall be held  invalid,  such
invalidity  shall not affect any other  provisions of this Agreement not held so
invalid,  and only such provisions shall to the full extent  consistent with the
law remain in full force and effect.

         15.  Applicable Law
              --------------

              This  Agreement  shall be  governed  by the  laws of the  State of
Connecticut.

<PAGE>
              IN WITNESS  WHEREOF,  the  parties  have  executed or caused to be
executed this Agreement as of the date first above written.


                                            DIANON SYSTEMS INC.




                                             BY: /s/ Richard A. Sandberg
                                                 --------------------------- 




                                             /s/ James B. Amberson
                                             ---------------------------
                                             JAMES B. AMBERSON, M.D.

<PAGE>
                                                                     Exhibit A
                                                                     --------- 

                                    AGREEMENT
                                    ---------

         THIS  AGREEMENT  made this 1st day of  September,  1996 by and  between
DIANON  SYSTEMS,  INC.,  its  affiliates,  subsidiaries,  successors and assigns
(collectively called hereinafter  "DIANON") and James B. Amberson, an individual
residing in Weston, Connecticut (hereinafter called "Employee").

         In  consideration  of  Employment  Agreement of this date  Employee and
DIANON acknowledge, represent and agree to the terms and conditions set forth in
this Agreement.

         (1) Employee's  employment  with DIANON creates a relationship of trust
and  confidence  between the parties.  Employee  agrees  that,  during and after
his/her  employment  with DIANON,  Employee  will not use or disclose,  or allow
anyone else to use or disclose,  any  confidential  information  relating to the
products, sales and/or business affairs of DIANON or of any customer or supplier
of DIANON,  or any  information  created,  discovered,  or  developed  by or for
DIANON, or acquired by DIANON,  that has commercial value in DIANON's present or
future business ("Confidential Information"),  except as may be necessary in the
performance  of  Employee's  employment  with DIANON or as may be  authorized in
advance by  appropriate  officials of DIANON.  By way of  illustration,  but not
limitation,   Confidential  Information  includes  processes,   formulas,  data,
know-how, inventions, improvements,  techniques, marketing plans, product plans,
strategies,  forecasts,  customer lists and any other  information  Employee has
reason to know  DIANON  would  like to treat as  confidential  for any  purpose.
Employee  agrees to keep  Confidential  Information  secret  whether  or not any
document containing such information is marked confidential.

         (2) All rights, title and interest in all records, documents, files and
the business of DIANON,  whether or not produced by the  Employee,  shall be and
remain the property of DIANON.  Upon  termination  of  employment,  the Employee
shall not have the right to remove any such records  frorm the office of DIANON.
In  addition,  Employee  agrees  to  promptly  return to  DIANON  all  things of
whatsoever  nature that belongs to DIANON,  and all records (in whatsoever form,
format or medium) containing or related to Confidential Information of DIANON.

<PAGE>
         (3) The Employee shall,  while employed by DIANON,  devote his/her best
efforts and his/her full time to the business of DIANON.

         (4) In the event of a breach or threatened  breach of the provisions in
this  Agreement,  DIANON  shall be entitled to an  injunction  restraining  such
breach,  it being  recognized  that any injury  arising  from a breach  would be
irreparable  and would have no adequate  remedy at law; but nothing herein shall
be construed as prohibiting  DIANON from pursuing any other remedy available for
such  breach of  threatened  breach.  In the event  that  Employee  breaches  or
threatens  a breach of this  Agreement,  DIANON  shall be  entitled  to have its
reasonable  legal fees and costs  paid by the  Employee  for any legal  services
relating to the breach or threatened breach.

         (5) This Agreement is not intended,  and should not be construed in any
way, as a contract of  employment  for a definite  period of time or to limit or
restrain   DIANON's  or  the  Employee's   right  to  terminate  the  employment
relationship at any time.

         (6) In the  event any  provision  or  paragraph  of this  Agreement  is
declared  to be invalid or  unenforceable,  then the  balance of this  Agreement
shall remain in full force and effect.

         (7) This Agreement  shall be construed and enforced in accordance  with
the laws of the State of Connecticut.

         (8) The  foregoing  contains the entire  Agreement  between the parties
pertaining to confidential  DIANON  documents and  information.  No modification
thereof shall be binding upon the parties unless the same is in a writing signed
by the  respective  parties.  This Agreement and all of the terms and conditions
contained  herein  shall  remain in full force  during the period of  employment
notwithstanding any change in compensation.

<PAGE>
         (9)  Employee   represents  and  warrants  that  he/she  has  no  other
agreements or  commitments  that would hinder or prevent  performance of his/her
job  responsibilities  with DIANON.  Unless authorized to do so, Employee agrees
not to disclose to DIANON or use in his/her employment with DIANON any invention
or  confidential  information  belonging to any former  employer or to any other
person other than DIANON.

         IN WITNESS WHEREOF,  the parties have entered into this Agreement as of
the date set forth above.

 
Employee:                                      DIANON SYSTEMS, INC.


/s/ James B. Amberson                   By:    /s/ Richard A. Sandberg
- ---------------------                          -----------------------


Date:  9/1/96                           Date:  9/1/96
       --------------                          -----------------------   



                         EXECUTIVE EMPLOYMENT AGREEMENT
                         ------------------------------

              AGREEMENT,  dated as of 9/1/96,  by and  between  DIANON  Systems,
Inc., a Delaware corporation having offices at 200 Watson Boulevard,  Stratford,
Connecticut 06497 (the "Company"),  and James B. Amberson, whose residence is 18
Tubbs Spring Court, Weston, Connecticut 06883 (the "Executive").

              The  Company's  Board of Directors  (the  "Board")  considers  the
continued  services of key  executives of the Company to be in the best interest
of the Company and its stockholders.

              The  Board  desires  to  assure,  and  has  determined  that it is
appropriate  and in the best  interests of the Company and its  stockholders  to
reinforce  and  encourage,   the  continued  attention  and  dedication  of  key
executives  of the  Company to their  duties  without  personal  distraction  or
conflict of interest in circumstances arising from the possibility or occurrence
of a change in control of the Company.

              In  consideration of the premises and the covenants and agreements
contained herein, and other good and valuable consideration, the Company and the
Executive agree as follows:

         1. Services During Certain  Events.  In the event a proposal is made to
effect a Change in Control  (as  defined in  Section 3  hereof),  the  Executive
agrees  that he will not  voluntarily  leave the employ of the  Company and will
render the services  contemplated  in the recitals of this Agreement  until such
proposal for a Change in Control is terminated or abandoned or until a Change in
Control has occurred, except as otherwise provided in Section 2 hereof.

         2. Termination.  For purposes of this Agreement,  a "Termination" shall
be deemed to have occurred in the event that the  Executive's  employment by the
Company is  terminated  at any time from 90 days prior to a Change in Control to
two years following a Change in Control:

              (a) by the Company for reasons  other than  "cause" (as defined in
Section 6 hereof),  "disability"  (as  defined  in  Section 6 hereof),  death or
attainment of age 65;

              (b)  by  the  Executive  following  the  occurrence  of any of the
following events without the Executive's consent:

                    (i) the  assignment  of   the  Executive  to  any  duties or
         responsibilities  that  are  inconsistent  with his  position,  duties,
         responsibilities  or  status  immediately   preceding  such  Change  in
         Control, or a change in his reporting responsibilities or titles within
         the  Company in effect at such time  resulting  in a  reduction  of his
         responsibilities or position at the Company;

                   (ii) a reduction of the Executive's annual salary;

                  (iii) a  material  reduction  in  any  year of  the  ratio  of
         incentive  compensation  or fringe  benefits  received by the Executive
         pursuant to any bonus,  incentive or fringe  benefit plan (the "Benefit
         Plan") to his annual  salary in such year,  which  reduction is greater
         than the average  reduction in the ratio of such incentive compensation

<PAGE>
         or fringe benefits to annual salary received by all participants  under
         the Benefits Plans;

                   (iv) a material  increase  in the  amount of travel  normally
         required of the  Executive in  connection  with his  employment  by the
         Company,  or the transfer of the  Executive  to a location  requiring a
         change in his residence; or

                    (v) any  failure by the  Company to comply with an d satisfy
         Section 8 of this Agreement; or

              (c) by the Executive,  if he determines,  in his sole  discretion,
during the 60-day period commencing 180 days following a Change in Control, that
due to the Change in Control he can no longer  effectively  perform  his duties.
For purposes of this Agreement,  any determination by the Executive  pursuant to
the preceding sentence shall be conclusive.

         3. Change in Control.  For  purposes  of this  Agreement,  a "Change in
Control" of the Company shall be deemed to have occurred if:

              (a) individuals who, as of the date hereof,  constitute the entire
Board of  Directors  of the Company (the  "Incumbent  Directors")  cease for any
reason to constitute at least a majority of the Board,  provided,  however, that
any  individual  becoming a director  subsequent  to the date of this  Agreement
whose election,  or nomination for election by the Company's  shareholders,  was
approved  by a vote of at  least a  majority  of the then  In-cumbent  Directors
(other than an election or  nomination  of an  individual  whose  assumption  of
office is the result of an actual or threatened election contest relating to the
election  of  directors  of the  Company,  as such terms are used in Rule 14a-11
under the  Securities  Exchange Act of 1934, as amended (the  "Exchange  Act")),
shall be, for purposes of this  Agreement,  considered as though such individual
were an Incumbent Director; or

              (b)  the  shareholders  of  the  Company  shall  approve  (i)  any
consolidation  or  recapitalization  of the Company (or, if the capital stock of
the Company is affected,  any subsidiary of the Company) or any sale,  lease, or
other transfer (in one transaction or a series of  transactions  contemplated or
arranged  by any  party as a single  plan)  of all or  substantially  all of the
assets of the Company (each of the foregoing being an "Acquisition Transaction")
where (x) the shareholders of the Company  immediately prior to such Acquisition
Transaction   would  not   immediately   after  such   Acquisition   Transaction
beneficially own, directly or indirectly,  shares  representing in the aggregate
more  than  65% of (A) the then  outstanding  common  stock  of the  corporation
surviving or resulting from such merger,  consolidation or  recapitalization  or
acquiring  such  assets  of the  Company,  as the  case  may be (the  "Surviving
Corporation")  (or of its  ultimate  parent  corporation,  if  any)  and (B) the
Combined  Voting  Power  (as  defined  below)  of the  then  outstanding  Voting
Securities (as defined below) of the Surviving  Corporation  (or of its ultimate
parent  corporation,  if any) or (y) the Incumbent  Directors at the time of the
initial approval of such  Acquisition  Transaction  would not immediately  after
such Acquisition  Transaction constitute a majority of the Board of Directors of
the Surviving  Corporation  (or of its ultimate parent  corporation,  if any) or
(ii) any plan or proposal for the liquidation or dissolution of the Company; or

              (c) any Person (as  defined  below)  shall  become the  beneficial
owner (as defined in Rules 13d-3 and 13d-5 under the Exchange Act),  directly or
indirectly,  of securities of the Company  representing  in the aggregate 30% or
more of either  (i) the then  outstanding  shares of the  Company  Common  Stock

<PAGE>
("Common  Stock"),  or (ii) the Combined  Voting  Power of all then  outstanding
Voting Securities of the Company;  provided,  however,  that notwithstanding the
foregoing,  a Change  in  Control  of the  Company  shall  not be deemed to have
occurred for purposes of this subsection (c) solely as the result of:

                   (i) the  acquisition of securities by the Company  which,  by
         reducing  the  number  of  shares  of  Common  Stock  or  other  Voting
         Securities  outstanding,  increases  (i) the  proportionate  number  of
         shares of Common Stock  beneficially owned by any Person to 30% or more
         of  the  shares  of  Common   Stock  then   outstanding   or  (ii)  the
         proportionate   voting  power  represented  by  the  Voting  Securities
         beneficially  owned by any Person to 30% or more of the Combined Voting
         Power of all then outstanding Voting Securities; or

                  (ii) an  acquisition of securities if the Incumbent  Directors
         at the time of the  initial  approval  of such  acquisition  would  not
         immediately  after  (or  otherwise  as a result  of)  such  acquisition
         constitute a majority of the Board;

                        (A) any  conversion  of a security that was not acquired
              directly from the Company; or

                        (B)  any  acquisition  of  securities  if the  Incumbent
              Directors at the time of the initial  approval of such acquisition
              would not  immediately  after (or  otherwise  as a result of) such
              acquisition constitute a majority of the Board;

provided,  however, that if any Person referred to in subsections (i) or (ii) of
this clause (c) shall  thereafter  become the beneficial owner of any additional
shares of the Company  Common  Stock or other Voting  Securities  of the Company
(other than pursuant to a stock split, stock dividend or similar  transaction or
an  acquisition  exempt under such  subsection  (ii)),  then a Change in Control
shall be deemed to have occurred for purposes of this clause(c).

              (d)  Notwithstanding  anything  contained in this Agreement to the
contrary,  if the  Executive  experiences  a  Termination  prior to a Change  in
Control and the Executive reasonably  demonstrates that such Termination (A) was
at the request of a Third Party (as defined below) or (B) otherwise  occurred in
connection with or in anticipation of a Change in Control, then for all purposes
of the  Agreement,  the  date of such  Change  in  Control  shall  mean the date
immediately prior to the date of such Termination.

              For purposes of this Agreement:

              "Person" shall mean any  individual,  entity  (including,  without
limitation, any corporation,  partnership,  trust, joint venture, association or
governmental  body and any successor to any such entity) or group (as defined in
Sections  13(d)(3) or 14(d)(2) of the Exchange Act and the rules and regulations
thereunder); provided, however, that Person shall not include the Executive, the
Company, any of its majority-owned  subsidiaries,  any executive benefit plan of
the Company or any of its  majority-owned  subsidiaries or any entity organized,
appointed  or  established  by  the  Executive,   the  Company  or  any  of  its
majority-owned  subsidiaries  for or pursuant to the terms of any such plan,  or
any of their affiliates;

<PAGE>
              "Voting  Securities"  shall mean all  securities  of a corporation
having the right  under  ordinary  circumstances  to vote in an  election of the
board of directors of such corporation;

              "Combined Voting Power" shall mean the aggregate votes entitled to
be case  generally in the election of directors of a  corporation  by holders of
then outstanding Voting Securities of such corporation; and

              "Third  Person"  shall  mean a third  party who has  indicated  an
intention, or taken steps reasonably calculated, to effect a Change in Control.

         4. Rights and Benefits upon Termination or Change in Control.

              (a) Severance  Payment.  Subject to Section 6 and 11(a) hereof, in
the event of a Termination the Company shall pay the Executive,  in twelve equal
monthly  installments  beginning no later than 30 days following the Executive's
Termination,  (i) the  greater  of the  Executive's  annual  salary as in effect
immediately prior to (x) the Termination or (y) a Change in Control plus (ii) if
a Change of Control  could have been  deemed to occur as a result of meeting the
conditions  set forth in paragraph 3(a) hereof  (whether or not such  conditions
were the sole reason for a Change of Control), the most recent annual bonus paid
the Executive.  In the event of the  Executive's  death,  such payments shall be
made to Executive's estate or other legal representative.

              (b) Stock Options.  Immediately prior to a Change in Control,  all
outstanding  options  to buy  Company  stock held by the  Executive,  other than
options granted  pursuant to the Company's  Employee Stock Purchase Plan,  shall
become fully vested and immediately exercisable.

              (c) Restricted  Stock.  Immediately  prior to a Change in Control,
any (i) repurchase  agreement or (ii) right of first refusal  agreement  between
the Executive and the Company with respect to the Company stock shall  terminate
and the Executive's ownership of all shares of Company stock shall fully vest.

         5.  Certain  Additional  Payments  by the  Company.  Anything  in  this
Agreement to the contrary  notwithstanding,  in the event it shall be determined
that any  payment,  distribution  or other  action by the  Company to or for the
benefit of the  Executive,  whether  pursuant to the terms of this  Agreement or
otherwise (a  "Payment"),  would be subject to the excise tax imposed by Section
4999 of the Internal  Revenue Code or any interest or penalties  with respect to
such excise tax (such excise tax, together with any such interest and penalties,
are  hereinafter  collectively  referred  to as  the  "Excise  Tax"),  then  the
Executive,  if such Executive has been employed by the Company for five years or
more,  shall be entitled to receive from the Company at the time such Excise Tax
is due an  additional  payment (a "Gross-Up  Payment") in any amount  reasonably
calculated by the Company's  independent auditors such that after payment by the
Executive of all taxes (including any interest or penalties imposed with respect
to such taxes), including any Excise Tax, imposed upon the Gross-Up Payment, the
Executive  retains  an amount of the  Gross-Up  Payment  equal to the Excise Tax
imposed upon the Payments.

         6.  Conditions  to the  Obligations  of the  Company.  The  rights  and
benefits  provided in Section 4 hereof shall not accrue to the  Executive if any
of the following events shall occur:

<PAGE>
              (a) The Company shall  terminate the  Executive's  employment  for
"cause." For purposes of this  Agreement,  termination of employment for "cause"
shall mean (i) the Executive's  conviction for, or plea of nolo contendere to, a
felony, (ii) the Executive's engaging in fraud,  misappropriation,  embezzlement
or other act or acts of  dishonesty  resulting  in, or  intended  to result  in,
substantial  personal  enrichment of the Executive at the expense of the Company
or (iii) the Executive's  intentional  and continual  failure  substantially  to
perform  his duties with the Company  (other than a failure  resulting  from the
Executive's  incapacity  due to physical or mental  illness)  which  failure has
continued for a period of at least 30 days after a written  notice of demand for
substantial  performance  has been  delivered  to the  Executive  specifying  in
reasonable  detail the manner in which the Executive has failed to substantially
perform.  Notwithstanding  the foregoing,  the Executive  shall not be deemed to
have been  terminated for cause unless and until there shall have been delivered
to the Executive a copy of a resolution  (x) duly adopted by  three-quarters  of
the  entire  membership  of the  Board,  at a meeting  called  and held for such
purpose  after  reasonable  notice  to  Executive  and an  opportunity  for  the
Executive,  together with the Executive's counsel, to be heard before the Board,
and (y)  finding  that in the good faith  opinion of the  Board,  Executive  was
guilty of  conduct  described  in the  preceding  sentence  and  specifying  the
particulars of such conduct in detail.

              (b)  Following  a  Termination,  the  Executive  shall  not,  upon
receiving a written request to do so, resign as a director and/or officer of the
Company and of each  subsidiary and affiliate of the Company of which he is then
serving as a director and/or officer.

              (c) The Company shall  terminate the  Executive's  employment  for
"disability." For purposes of this Agreement, "disability" shall mean a physical
or psychological  condition of the Executive which renders him unable to perform
his duties for the Company for a period for six months or longer,  as  confirmed
in writing by the Executive's independent physician.

         7. Arbitration and Expenses.

              (a) Any dispute or controversy arising under or in connection with
this  Agreement  shall be settled by  arbitration,  conducted  before a panel of
three arbitrators in Stamford,  Connecticut, in accordance with the rules of the
American  Arbitration  Association  then in  effect.  The  arbitrators  shall be
approved by both the  Company  and the  Executive  and their  decision  shall be
binding on the parties and conclusive for all purposes.  Judgment may be entered
on the arbitrators' award in any court having jurisdiction.  The expense of such
arbitration shall be borne by the Company.

              (b) The Company shall pay or reimburse the Executive for all costs
and  expenses  (including,  without  limitation,   reasonable  attorneys'  fees)
incurred  by the  Executive  as a result  of any  claim,  action  or  proceeding
(including,  without limitation,  a claim, action or proceeding by the Executive
against the Company)  arising out of, or challenging the validity,  advisability
or enforceability of, this Agreement or any provision hereof.

         8. Successors.  The Company shall require any successor (whether direct
or  indirect,  by  purchase,  merger,  consolidation  or  otherwise)  to  all or
substantially all of the business or assets of the Company, by agreement in form
and  substance  satisfactory  to  the  Executive,   expressly,   absolutely  and

<PAGE>
unconditionally to assume and agree to perform this Agreement in the same manner
and to the same extent  that the  Company  would be required to perform it if no
such succession had taken place. As used herein, "the Company" shall include any
successor to all or substantially all of the Company's  business or assets which
executes  and  delivers an  agreement  provided  for in this  Section 8 or which
otherwise  becomes bound by all the terms and  provisions  of this  Agreement by
operation of law.

         9. Notice of Termination. Any termination of the Executive's employment
by the Company shall be  communicated  to the Executive at the address set forth
above (or such other address as the Executive shall have notified the Company in
writing for  purposes of this  Agreement)  in a written  notice and,  except for
termination for "cause," shall specify a termination date no sooner than 15 days
after the giving of such notice.

         10. Term of  Agreement.  This  Agreement  shall  terminate on the fifth
anniversary of the date hereof;  provided,  however,  that this Agreement  shall
automatically  renew for successive one-year terms unless the Company's Board of
Directors  notifies  the  Executive  in  writing  at least  30 days  prior to an
expiration  date that it does not wish to renew the  Agreement for an additional
term; and provided further that if a Change in Control occurs during the term of
an additional term of this Agreement, the Agreement shall continue in effect for
two years following such Change in Control.

         11. Miscellaneous.

              (a) Duty to Mitigate:  Other Severance Payments.  If a Termination
is deemed to occur, the Executive shall during the one-year period subsequent to
his  Termination  notify the Company of any employment  when  obtained,  and the
severance  payment  provided  under  Section  4(a) hereof shall be offset by any
compensation,  which he receives from such employment during the one-year period
subsequent to this  Termination.  Furthermore,  the severance  payment  provided
under  Section 4(a) hereof shall also be offset by any other  severance  payment
which the Executive  receives under any  employment  agreement with the Company,
including damages for breach of any such agreement.

              (b) Assignment.  No right,  benefit or interest hereunder shall be
subject to assignment,  anticipation,  alienation,  sale,  encumbrance,  charge,
pledge, hypothecation or set-off in respect of any claim, debt or obligation, or
to execution,  attachment,  levy or similar process; provided, however, that the
Executive may assign any right, benefit or interest hereunder if such assignment
is  permitted  under the terms of any plan or policy  of  insurance  or  annuity
contract governing such right, benefit or interest.

              (c) Construction of Agreement.  Nothing in this Agreement shall be
construed  to amend any  provision  of any plan or policy of the  Company.  This
Agreement is not, and nothing herein shall be deemed to create,  a commitment of
continued employment of the Executive by the Company.

              (d)  Amendment.  This  agreement  may not be amended,  modified or
canceled except by written agreement of the parties.

              (e) Waiver. No provision of this Agreement may be waived except by
a writing signed by the party to be bound thereby.

              (f)  Severability.  In the event that any  provision or portion of
this  Agreement  shall be  determined  to be  invalid or  unenforceable  for any
reason,  the remaining  provisions of this Agreement  shall remain in full force
and effect to the fullest extent permitted by law.

<PAGE>
              (g) Taxes.  Any payment or delivery  required under this Agreement
shall be subject to all  requirements  of the law with regard to  withholding of
taxes,  filing,  making of reports and the like,  and the Company  shall use its
best efforts to satisfy promptly all such requirements.

              (h) Governing Law. This Agreement  shall be governed and construed
in accordance with the laws of the State of New York.

              (i)  Entire  Agreement.  This  Agreement  sets  forth  the  entire
agreement and  understanding  of the parties  hereto with respect to the matters
covered hereby.

                                            DIANON SYSTEMS, INC.


                                            By:  /s/ Richard A. Sandberg
                                                 ------------------------


                                            /s/ James B. Amberson
                                            ------------------------------
                                            James. B. Amberson, M.D.







                              SEPARATION AGREEMENT


         WHEREAS,  CARL IBERGER and DIANON SYSTEMS, INC. ("Company") wish to end
the employment relationship between them and wish to resolve any and all claims,
disputes or causes of action that do or may exist between them;

         NOW  THEREFORE,  in  consideration  of the mutual  covenants  and other
valuable considerations  contained herein, the Company and CARL IBERGER agree as
follows:

         1. CARL  IBERGER  resigns  his  full-time  employment  and his  officer
positions with the Company effective as of September 27, 1996.

         2. The  Company  shall pay CARL  IBERGER  separation  pay,  subject  to
applicable  deductions,  in the  amount  of  twenty-six  thousand,  six  hundred
eighty-three  dollars ($26,683)  representing the difference  between pay at his
last rate of base salary for the period of nine months  after  termination  (the
"Separation  Period") and the gross amount of a  performance  bonus  awarded him
during the course of his employment.  This separation pay shall be paid in equal
installments on regular  payroll dates of the Company  throughout the Separation
Period.

         3. The Company  shall pay CARL IBERGER the bonus he would have received
under  the  Company's  1996  Management  Incentive  Program  had his  employment
continued  through the date on which payments under said program are made.  This
payment  will be made at the same time  payments to other  Management  Incentive
Program participants are made.

         4. CARL IBERGER  agrees to comply with the  provisions  of the Employee
Proprietary  Information  Agreement  appended  to this  Agreement  as Exhibit A,
subject to Paragraph 9 of this Agreement.

<PAGE>
         5.  CARL  IBERGER   agrees  to  cooperate  with  the  Company  and  its
representatives  regarding  any claims or potential  claims or  litigation by or
against  the  Company  involving  matters  about  which CARL  IBERGER  possesses
knowledge.  It is the intent of the parties to require CARL  IBERGER's  physical
presence at a site remote from his home or business  only when  necessary to the
effective delivery of such cooperation.

         6. CARL IBERGER, agrees to make himself reasonably available to consult
with the Company on financial and  administrative  matters during the Separation
Period.

         7. CARL IBERGER,  on behalf of himself,  his executors,  administrators
and assigns,  hereby releases the Company, its affiliates,  and their respective
directors,   officers,   agents,  employees,   benefit  plans,  fiduciaries  and
administrators   of  such  benefit  plans  and  their   successors  and  assigns
(hereinafter  "Released  Company  Parties") from any and all claims or causes of
action of any kind arising on or before the date he signs this Agreement,  other
than vested rights under benefit plans,  which CARL IBERGER has, had or may have
against  any of them,  whether  or not now known  arising  from  CARL  IBERGER's
recruitment for employment with the Company, his employment or officer positions
with the Company,  or the  termination of his  employment and officer  positions
with  the  Company,  including  without  limitation  any  claims  under  the Age
Discrimination in Employment.

         8.  CARL   IBERGER  on  behalf  of  himself,   his  heirs,   executors,
administrators  and assigns,  further  agrees never  directly or  indirectly  to
commence or prosecute, or to permit or advise to be commenced or prosecuted, any
action,  proceeding,  or charge against any Released Company Party, in any state
or federal  court,  administrative  agency or arbitral forum with respect to any
matter  whether or not  known,  for any claim  based upon any act,  transaction,

<PAGE>
practice,  conduct,  or omission that  occurred  prior to the date he signs this
Agreement,  including but not limited to, rights under the Age Discrimination in
Employment Act or any other federal, state, or local laws prohibiting age, race,
sex, national origin,  religion,  or other forms of  discrimination,  claims for
breach of contract or promissory estoppel or tort, and claims growing out of any
legal restrictions on the Company's right to terminate its employees or officers
which he now has,  or claims to have,  or which at any time  heretofore  had, or
which at any time hereafter may have.

         9.  Notwithstanding  the  provisions  of  the  Employment   Proprietary
Information  Agreement  attached hereto as Exhibit A, the Company  releases CARL
IBERGER from the obligation not to engage in any similar or competitive business
entity or research as of the  expiration of the Separation  Period.  The parties
further agree that should CARL IBERGER  engage in such activity or research with
any entity  principally  engaged in urology  testing  and/or  pathology  testing
during the Separation Period, the Company's obligation to make payments pursuant
to Paragraphs 2 and 3 of this Agreement  shall terminate  without  affecting the
remaining provisions of this Agreement.

         10. The Company hereby releases CARL IBERGER from any and all claims or
causes of action of any kind  arising  on or before  the date it  executes  this
Agreement, which the Company has had or may have against him, whether or not now
known,  except any claims  involving  improper  actions by CARL IBERGER with the
intent or effect of personal gain to CARL IBERGER.

         11. The parties  recognize and agree that this  Agreement  does not and
shall not  constitute  an admission of liability or  wrongdoing  by any Released
Company Party.

<PAGE>
         12. The parties agree that, except as necessary to comply and to obtain
compliance with this Agreement,  or to comply with any federal,  state, or local
law, they will not disclose the terms of this Agreement.

         13. In the event  CARL  IBERGER  files a claim,  lawsuit  or  complaint
against any  Released  Company  Party in any court or  governmental  agency with
respect to the claims he has released under this  Agreement,  CARL IBERGER shall
be liable for all costs and  expenses  including  legal  fees,  incurred  by any
Released Company Party in defense of that action. In the event the Company files
a claim,  lawsuit or complaint against CARL IBERGER in any court or governmental
agency with  respect to the claims it has  released  under this  Agreement,  the
Company  shall be liable  for all  costs and  expenses,  including  legal  fees,
incurred by CARL IBERGER in defense of that action.

         14. CARL IBERGER  represents  that he has carefully read and completely
understands  this  Agreement  and  that  he  has  entered  into  this  Agreement
voluntarily  after having had an opportunity to consult with his legal advisors,
which he has been encouraged to do in writing by the Company (Exhibit B).

         15.  CARL  IBERGER  acknowledges  that  the  commitments,  waivers  and
releases he gives in this  agreement are in exchange for valuable  consideration
to which he is not otherwise  entitled,  and which constitutes a full accord and
satisfaction of any claims he may have against any Released Party.

         16. CARL IBERGER  acknowledges  that he has been given  twenty-one (21)
days to review the waivers and  releases  contained in this  Agreement  prior to
signing it.

<PAGE>
         17. CARL IBERGER  shall have seven (7) days after the execution of this
Agreement to revoke the waivers and releases  contained  in this  Agreement  and
this Agreement shall not be effective unless and until those seven (7) days have
elapsed without CARL IBERGER so revoking.

         18. This Agreement  constitutes the entire  Agreement of the parties on
the  subject  matter  hereof  and  supersedes  any  and  all  prior  agreements,
understandings or commitments, oral or written.

         19. This Agreement shall be governed by applicable  Federal law and the
laws of the State of Connecticut.


                                            CARL IBERGER


Dated:  9/19/96                             Signature:  /s/ Carl Iberger
        -------                                         --------------------


                                            DIANON SYSTEMS, INC.


Dated:  9/19/96                             Signature:  /s/ Kevin C. Johnson
        -------                                         -------------------- 




                              EMPLOYMENT AGREEMENT


         This  AGREEMENT  made  effective  September  30,  1996  between  DIANON
SYSTEMS, INC., a Connecticut corporation, and any successor thereto, hereinafter
referred to as the "Company",  and DAVID  SCHREIBER,  residing at 1780 Nicholson
Drive, Hoffman Estates, Illinois 60192.

                                   WITNESSETH:

         WHEREAS,  the  Company  wishes  to  employ  David  Schreiber  and David
Schreiber  wishes  to  accept  such  employment,  in each  case on the terms and
subject to the conditions set forth below; and

         WHEREAS,  the services that David Schreiber  should render hereunder to
the Company are unique and valuable; and

         WHEREAS, the parties desire to reduce the terms and conditions of David
Schreiber's employment to writing;

         NOW,  THEREFORE,  in  consideration of the terms and conditions and the
mutual  covenants  contained in this Agreement,  the Company and David Schreiber
hereby agree as follows:

         1.  Employment
             ----------

             The Company hereby employs David Schreiber as of the first full day
of service he  provides to the  Company  hereunder  which shall be no later than
November 1, 1996 and David  Schreiber  hereby accepts such  employment  upon the
terms and conditions  hereinafter set forth. The parties  acknowledge that David
Schreiber's  employment  with the  Company is at will and  terminable  by either
party at any time for any reason.

         2.  Duties and Responsibilities
             ---------------------------

             David  Schreiber,  as  Chief  Financial  Officer  and  Senior  Vice
President,  Finance,  shall perform with continuous  diligence those  activities
assigned to David  Schreiber by the Company's  President or, in the absence of a
President, its Board of Directors. Commencing with the first full day of service
he provides to the Company  hereunder,  David Schreiber will be elected as Chief
Financial Officer and Senior Vice President, Finance, of the Company.

<PAGE>
         3.  Term
             ----

             This  Agreement  shall  begin  on the  effective  date  hereof  and
continue until terminated under the terms contained herein.

         4.  Salary and Incentive Compensation
             ---------------------------------

             The Company  shall  compensate  David  Schreiber  for his  services
during the term of this Agreement  commencing with the first full day of service
he provides to the Company hereunder on a salaried basis paid in installments at
a rate  determined  by the Company from time to time,  provided that the initial
base salary  shall be at an  annualized  rate of $190,000.  Commencing  with the
first full day of service he provides to the Company hereunder,  David Schreiber
shall also  participate,  according to its terms,  in any  management  incentive
compensation  program maintained by the Company for salaried Grade 18 management
employees  of the  Company  during  the  term of this  Agreement.  A copy of the
Management Incentive Plan currently in effect is attached as Exhibit A.

         5.  Fringe Benefits
             ---------------

             During the term of this  Agreement,  commencing with the first full
day of service he provides to the Company  hereunder,  the Company shall provide
David  Schreiber  benefits and  emoluments as authorized  for all other salaried
Grade 18  management  employees of the Company as they may be modified from time
to time by the Company during the term of this Agreement,  including at the time
of execution of this Agreement,  health and medical  insurance,  life insurance,
sick leave, vacation, holidays, retirement plan participation and stock purchase
plan participation.  In addition, the Company shall provide David Schreiber with
a  Company-leased  automobile for his use and shall  reimburse him in accordance
with  Company  practice for business  related  fuel usage,  routine  maintenance
expenses, and auto insurance expense.

         6.  Stock Options
             -------------

             Upon  execution of this  Agreement,  the Company  shall award David
Schreiber  Incentive  Stock Options to purchase 50,000 shares of common stock of
the Company at the fair market value on said date, on term, conditions,  vesting
schedules and expiration dates which are  substantially  equivalent to the stock
option award document attached to this Agreement as Exhibit B.

         7.  Signing Bonus
             -------------

             Upon  execution  of this  Agreement,  David  Schreiber  shall earn,
payable upon his first day of employment, a signing bonus of $80,000 (subject to
appropriate withholding taxes) payable by the Company.

<PAGE>
         8.  Stock Grants
             ------------

             Provided David  Schreiber's  employment with the Company  continues
through the date below without  notice of intent to terminate  having been given
by either  party,  the Company  shall issue to David  Schreiber  7,500 shares of
common stock of the Company on April 1, 1997. David Schreiber agrees not to sell
any such stock for a period of six months from the date of such grant.

         9.  Relocation
             ----------

             The Company shall pay for and reimburse  expenses  associated  with
David  Schreiber's  relocation  connected  with his hire in accordance  with the
Company's policy on Relocation and Moving Expenses,  a copy of which is attached
to this  Agreement  as Exhibit C;  provided  further  that,  the  Company  shall
compensate David Schreiber if his current res-idence is sold prior to January 1,
1997,  pursuant to said  policy's  guaranteed  home sale plan or otherwise in an
arms length  transaction,  at a price  insufficient  to  compensate  him for his
equity in the  residence at the time of sale,  including  the value of permanent
improvements  made by him (the  amount of which  equity  including  improvements
shall be  determined  by the Company on the basis of  appropriate  documentation
satisfactory to the Company to be supplied by David  Schreiber,  but which in no
event shall exceed $115,000). Any such equity compensation shall be subject to a
gross up  payment  for tax  purposes  as  described  in  Section  III(I)  of the
Company's policy on Relocation and Moving Expenses.

         10. Termination
             -----------  

             a)  This  Agreement   shall  terminate  on  any  of  the  following
occurrences:

                   (i) David Schreiber's death
                  (ii) David  Schreiber's  disability for a period of 90 days or
                       more unless waived by the Board of Directors;
                 (iii) mutual  agreement  of  the  parties  reduced  to  writing
                       signed by both parties;
                  (iv) voluntary resignation by David Schreiber
                   (v) termination by the Company without Stated Cause;
                  (vi) termination by the Company with Stated Cause.

             b) Cause shall mean David Schrieber's

                   (i) gross negligence
                  (ii) insubordination;
<PAGE>
                 (iii) willful misconduct;

             c) "Stated Cause" shall mean Cause  communicated to David Schreiber
by the Company in a Notice of Termination.

             d) "Notice of  Termination"  shall mean written  notice given to by
either party to the other of an intention to terminate this  Agreement  pursuant
to subparagraphs (a) (iv), (v) or (vi) of this Paragraph of this Agreement.

             e) Notice  of  Termination  shall  be  sent by  certified  mail  or
registered mail, return receipt requested,  first class postage prepaid,  to the
residence in the case of David  Schreiber,  and to its  principal  office in the
Town of Stratford, Connecticut, to the attention of the President.

             f) The "Termination  Date" shall be the date David Schreiber ceases
providing services to the Company as an employee.

         11. Compensation after Termination
             ------------------------------

             a) David  Schreiber  will not  receive  any  compensation  from the
Company after the Termination Date other than accrued,  unused vacation,  except
as  described  under  Paragraph  (b) of  this  Section  of  this  Agreement,  if
applicable.  David Schreiber's  participa-tion in all fringe benefits offered by
the Company to its employees  will cease  immediately  on the  Termination  Date
except as  described in Paragraph  (b) of this  section of this  Agree-ment,  if
applicable. Nothing in this Agreement, however, is intended to impair any rights
vested under the law in any benefit plan in the Company.

             b) If this  Agreement  and David  Schreiber's  employment  with the
Company is  terminated  by the Company  without  Stated  Cause,  then during the
applicable  "Post  Termination  Period"  described in  subparagraph  (v) of this
paragraph:

                   (i) The Company will  pay David Schreiber at his rate of base
                       pay determined as of the  day  preceding the  Termination
                       Date.

                  (ii) David Schreiber shall act as a consultant to the Company
                       as requested by the Company for up to six days per month.

                 (iii) The Company  will contribute  towards the premium cost of
                       medical continuation  coverage for David Schreiber and/or
                       his  dependents on the same basis as it then  contributes
                       towards the medical  coverage of active  employees and/or
                       their  dependents,  for any months in said period  during
                       which David Schreiber  and/or his dependents are eligible
                       and elect to continue such coverage.

<PAGE>


                  (iv) The  Company  will  pay up to  $10,000  for  outplacement
                       services for David Schreiber  provided by an outplacement
                       provider of David Schreiber's choice.

                   (v) If   termination   occurs   within   the  first  year  of
                       employment,  or at a later  time but  within  six  months
                       after the Company's  being  acquired by another  business
                       entity,  the "Post Termination  Period" shall be a period
                       of one year  beginning  with  the  Termination  Date.  If
                       termination  occurs after one year of employment has been
                       completed and absent an acquisition  of the Company,  the
                       "Post Termination Period" shall be a period of six months
                       beginning with the Termination Date.

         12. Company Property
             ----------------  

             On the  Termination  Date,  or at any earlier point in time after a
Notice of  Termination  is  received  when a request is made by the  Company for
same,  David  Schreiber  will  turn  over to the  Company  all  notes,  reports,
memoranda, books, records, chemicals, devices and documents, whether in written,
typewritten,  computerized  or any other  form,  which are in David  Schreiber's
possession or under his control,  whether prepared by him or others,  related to
the Company or relating to the business of the Company. At the conclusion of the
period  described in paragraph  (b) of Section 11 of this  Agreement,  or at any
earlier  point in time when a request  is made by the  Company  for same,  David
Schreiber shall also return to the Company any Company car, keys,  parking card,
credit card,  business cards or other materials  related to this employment with
the Company or the operation of the Company.

         13. Proprietary Information
             -----------------------

             David  Schreiber  hereby agrees to all the terms and  conditions of
the Agreement  regarding  confidential  Company  information  attached hereto as
Exhibit D and incorporated  herein and has executed a copy thereof  concurrently
with this Agreement.

         14  Non-Competition
             ---------------

             David  Schreiber  agrees that, to the fullest  extent  permitted by
law, for the period of one (1) year after his Termination  Date, David Schreiber
(a) will not solicit business on behalf of any entity in the clinical  chemistry
business,  which is performing or marketing  anatomic  pathology  services other
than  PAP  tests  ("Competing  Entity"),  (b)  will not  solicit  business  from
customers of the Company,  (c) will not solicit the  employ-ment  or services of
any of the employees of the Company,  and (d) will not,  directly or indirectly,
participate in the ownership,  management, operation or control of any Competing
Entity in the continental  United States other than  California,  Washington and
Oregon,  provided  that  nothing  in this  Paragraph  shall  prevent  investment
ownership of less than 5% of the shares of a publicly traded Competing Entity.

<PAGE>
         15. Remedy for Breach
             -----------------  

             David Schreiber acknowledges:

                  a)   that he may be an officer of the  Company  and as such he
                       would  be  conversant  with,  and  have  access  to,  the
                       business affairs,  records, trade secrets,  customers and
                       customer  lists,  suppliers,   supplier  lists,  patents,
                       technical   know-how,   chemicals,   devices,   sales  or
                       distribution   agents  and   representatives,   sales  or
                       distri-bution  agents  and  representatives'  lists,  and
                       other  confidential  and  proprietary  information of the
                       Company; and

                  b)   that his compliance  with the covenants and agreements in
                       this  Agreement  is necessary to protect the goodwill and
                       other proprietary interests of the Company; and

                  c)   that a breach of his  covenants  and  agreements  in this
                       Agreement  will  result  in  continuing  and  irreparable
                       damage to the Company for which there will be no adequate
                       remedy at law.

             Both the parties  recognize  that the services to be rendered under
this Agreement by David Schreiber are special and unique and of an extraordinary
character,  and that in the event  there is a breach by David  Schreiber  of the
terms and  conditions of this Agreement to be performed by him, then the Company
shall be entitled,  if it so elects,  to institute and prosecute  proceedings in
any  court of  competent  jurisdiction  either  in law or in  equity,  to obtain
damages for any breach of this Agreement, or to enforce the specific performance
thereof  by David  Schreiber,  or to  enjoin  David  Schreiber  from  performing
services for any Competing Entity.  The parties further recognize and agree that
breach by David  Schreiber of his obligations  under  Sections,  12, 13 or 14 of
this Agreement shall relieve the Company of its obligations  under paragraph (b)
of Section 11 of this  Agreement  but that such relief  shall not be an adequate
remedy at law.

         16. David Schreiber's Representation
             --------------------------------  

             David Schreiber  warrants and represents that neither the execution
and  delivery  nor the  performance  of this  Agreement  by him  will in any way
violate,  or conflict with, any other  agreement by which he may be bound or any
duty or  obligation  to which he may be subject  and that he will take all steps
necessary to comply with the representation.

         17. Assignments
             -----------  

             The rights and  obligations of David Schreiber under this Agreement
shall be  assignable  to and  binding  upon the  successors  and  assigns of the
Company  including  any  corporation  organized  by the  Company to carry on the
business of the Company.

<PAGE>
         18. Entire Agreement
             ----------------  

             This instrument  contains the entire  Agreement of the parties.  It
may not be changed orally,  but only by agreement in writing signed by the party
against  whom  enforcement  of any waiver,  change,  modification  extension  or
discharge is sought.  This  Agreement  supersedes  any verbal,  written or other
agreement(s)  or  understanding(s)  existing  between  David  Schreiber  and the
Company relating to his employment or the other matters covered herein.

         19. Severability
             ------------  

             If any  provision of this  Agreement  shall be held  invalid,  such
invalidity  shall not affect any other  provisions of this Agreement not held so
invalid,  and only such provisions shall to the full extent  consistent with the
law remain in full force and effect.

         20. Applicable Law
             --------------  

             This  Agreement  shall  be  governed  by the  laws of the  State of
Connecticut.

         IN WITNESS WHEREOF,  the parties have executed or caused to be executed
this Agreement.

                                            DIANON SYSTEMS, INC.


  September 30, 1996                        By: /s/ Kevin C. Johnson
- -----------------------                        ----------------------
Date                                           Kevin C. Johnson


    10/1/96                                 By: /s/ David Schreiber
- -----------------------                        ----------------------
Date                                           David Schreiber


<PAGE>

                                                                     Exhibit A
                                                                     --------- 

                             "STRIVE FOR EXCELLENCE"
                            MANAGEMENT INCENTIVE PLAN

PRINCIPLES:
- ----------

     A.   Provides  financial  incentive  for achieving  above average  results,
          specific objectives and performance.

     B.   Relates  rewards to specific  goals within each  individual's  area of
          responsibility as well as "shared" goals.

     C.   Disproportional  rewards superior vs. average performance by including
          a "Jackpot" provision.

     D.   Emphasizes  profitability  as the primary  company  goal by creating a
          bonus "pool" based on achieving operating income.

     E.   Maximizes full company motivation by including all management levels.


FORMULA:
- -------
                     I                II             III
                Maximum Bonus      Group          Individual
     Salary  X  As % of Salary  X  Goal       X   Goal         =  Incentive
                                   Achvmt. %      Achvmt. %       Compensation

Unless the Jackpot is  achieved,  a manager  cannot earn more than the  "maximum
bonus"  per cent of  his/her  salary.  The fact that the group goal can go above
100%  allows for some  offset in the event a manager  does not  achieve  each of
his/her individual goals.

Employees are eligible for MIP and other incentive  compensation or bonuses only
if  they  are  actively  employed  through  and  including  the day  payment  is
distributed.

Management may alter, modify or cancel this program as deemed necessary.


Maximum Bonus as % of Salary

<TABLE>
<CAPTION>

Grade                     Participation Timing         Max. Bonus as % of Salary
- -----                     --------------------         -------------------------

<S>                       <C>                                     <C>
19 President              From first work day                     40

18                        From first work day                     35

17 Vice Presidents        From first work day                     30

16                        Eligible after 90 days                  25

15 Managers               Eligible after 90 days                  20

14                        Eligible after 90 days                  15

13                        Eligible after 90 days                  10

</TABLE>

<PAGE>

                                                                     Exhibit B
                                                                     --------- 

                              DIANON SYSTEMS, INC.
                              200 Watson Boulevard
                          Stratford, Connecticut 06497

                                                         SO Grant No.

                               STOCK OPTION GRANT

<TABLE>
<CAPTION>

<S>                       <C>                        <C>                  <C> 
Optionee:                 David R. Schreiber         Date of Grant:       October 1, 1996

Termination Date:         September 30, 2006         Total No. of Shares:          50,000

Exercise Price Per Share              $6.625

</TABLE>

We are  pleased to inform you that the  Compensation  Committee  of the Board of
Directors of DIANON  Systems,  Inc.  (the  "Company"),  has today granted you an
option  pursuant to the  Company's  1991 Stock  Incentive  Plan (the  "Plan") to
purchase an  aggregate  number of shares  shown above of the Common Stock of the
Company on the following terms and conditions:

         1. The purchase  price per share of the shares of Common Stock  subject
to this option is $6.625 per share.

         2. This option shall  expire at the close of business on September  30,
2006. Subject to acceleration in the event of a Change of Control (as defined in
the Plan), you must remain in the employ of the Company or a Related Company (as
defined in the Plan) for two years from the date hereof  before you can exercise
any part of this  option.  Thereafter  this option will  become  exercisable  in
installments as follows:

             Percentage of Shares            Date of Earliest Exercise (Vesting)
             --------------------            -----------------------------------
                      40%                                  10/1/98
                      20%                                  10/1/99
                      20%                                  10/1/00
                      20%                                  10/1/01

         In the event of a Change of Control  this  option  shall  become  fully
exercisable and vested.

         3. This option is intended to qualify as an  "Incentive  Stock  Option"
within the provisions of Section 422 of the Internal Revenue Code.

         4. The option  price shall be payable by you at the time this option is
exercised,  (i) in cash or (ii) by  delivering  shares  of  Common  Stock of the
Company which you have owned for at least six months prior to such exercise,  or
a combination  of cash and such shares,  having an aggregate  value equal to the
aggregate  option  price of the  shares as to which  this  option  is  exercised
(basing the value of any such shares of Common Stock on the fair market value of
the Common  Stock on the date of  exercise).  No shares of Common Stock shall be
issued pursuant to exercise of this option until full payment  therefor has been
made.

           5.  This  option  may  be  exercised  only  by  you  and  may  not be
transferred except by will or the laws of descent and distribution. In the event
of your death,  your legal  representatives  may exercise  this option as to the
shares of Common Stock which were immediately  purchasable by you at the date of
death,  within  ninety  (90) days  following  the date of death (but in no event
later than September 30, 2006).

<PAGE>
         6. If your employment with the Company  terminates  after reaching your
normal  retirement  date under the Company's  retirement  plan or for any reason
beyond your  control  other than your death,  your  option  privileges  shall be
limited to the shares of Common Stock which were immediately  purchasable by you
at the date of such  termination and such option  privileges shall expire unless
exercised  within ninety (90 days) days after the date of such  termination  and
prior to the close of business on September  30,  2006.  If your  employment  is
terminated for reasons within your control, including without limitation,  cause
and voluntary resignation, all rights under this option shall expire on the date
of such termination.

         7. Your option is granted in tandem with a Limited  Stock  Appreciation
Right ("LSAR") which may be exercised only within the 60-day period  following a
Change of Control (as defined in the Plan). This means that with respect to each
share under  option,  you may  exercise  either the option or the Limited  Stock
Appreciation   Right,   but  not  both.  Upon  exercise  of  the  Limited  Stock
Appreciation Right, you shall receive,  for each share with respect to which the
Limited Stock Appreciation  Right is exercised,  an amount equal in value to (I)
the fair market  value of a share of Common  Stock on the date of exercise  over
(ii) the exercise price of the related  option.  The Limited Stock  Appreciation
Right shall be payable solely in cash.  Such amount shall be paid within 30 days
of the exercise of the Limited Stock Appreciation Right.

         8. The  Company  has the right to delay the  exercise of your option if
listing  registration or qualification of the Common Stock is required under any
federal or state  securities  law or stock  exchange or similar rule and has not
been obtained.

         9.  Nothing  herein  shall  restrict  the right of the  Company  or any
Related Company to terminate your employment at any time, with or without cause,
or to withhold  required  amounts upon the exercise of your option or LSAR.  The
Company  shall have the right to require you to pay, or make other  arrangements
satisfactory  to the Committee to satisfy,  all tax  withholding  obligations in
connection with the exercise of your option or LSAR.

         10. This option is subject to all of the other  terms,  provisions  and
conditions  of the  Plan,  a copy of which has been  furnished  to you and other
copies of which may be obtained by you from the Company.


                                            Very truly yours,

                                            DIANON Systems, Inc.



                                            By:
                                               ------------------------------
                                               Kevin C. Johnson
                                               President

Date:
     ----------------------


- ---------------------------
(Signature)


- ---------------------------
 (Address)


- ---------------------------


<PAGE>

                                                                     Exhibit C
                                                                     ---------
 
                         RELOCATION AND MOVING EXPENSES


I.   OBJECTIVE
     ---------     

       To define the conditions under, and the extent to which, the Company will
       pay for and reimburse  expenses  associated  with the relocation of newly
       hired and transferred employees.

II.  POLICY
     ------     

       A. The  decision  to  relocate  a newly  hired  or  transferred  employee
          requires the approval of the  department  Director/Vice  President and
          the Company's President.

       B. To facilitate  the  recruitment  and  reassignment  of employees,  the
          Company may provide payment of certain relocation  expenses consistent
          with the following criteria only if Section II A has been fulfilled.

          1.   The costs  associated with  relocations  under the policy require
               careful  consideration of the  cost/benefit  issues by management
               before such a relocation is initiated.

          2.   Provisions  of this  policy do not apply if the  employee  or new
               hire  relocates  less than 50 miles from  his/her  prior  primary
               residence.   Furthermore,   expenses  associated  with  only  the
               employee's or new hire's primary  residence will be considered as
               eligible for coverage.

          3.   The  coverages   provided  to  transferred   employees  are  more
               comprehensive   than  those  normally   provided  to  new  hires.
               Extension  of any  transferee  coverages  to new  hires  requires
               approval by the President or Chief Executive Officer.

          4.   Relocation benefits for employees  transferred for specified time
               periods  with planned  ending  dates are not included  under this
               policy.

          5.   Exceptions  to this policy must be approved by the  President  or
               Chief Executive Officer.

          6.   This company will  establish an expense limit on the  individuals
               total relocation costs.
This value will be approved in writing by the President.

III. PRACTICES
     ---------

       Generally  speaking,  relocation expenses will be capped. The cap will be
       directly  related  to  the  position  being  filled  and  established  in
       conjunction  with II. A. (above)  prior to extending a relocation  offer.
       The maximum allowance values are for company budgeting  purposes of these
       specific items,  and do not reflect nor are they intended to suggest that
       the  employee is  authorized  to commit or incur these  expenses  without
       satisfying Part Ia (above) for each part III section.

<PAGE>
       The following  items will be paid for or reimbursed as described  herein.
       Coverages are summarized in Exhibit "A" to this policy and are contingent
       on Section II A.

A.   "House-Hunting" Trips -
     ----------------------

       The Company will  reimburse the employee the expenses  incurred for up to
       two,three-day trips to search for and select a new residence. Included as
       reimbursable  expenses are travel, hotel,  babysitter,  and meal expenses
       for the employee and spouse.

B.   Physical Move -
     -------------

       The Company will pay the cost of moving  furniture and household goods to
       the  new  location,   including  insurance,   packing,   unpacking,   and
       installation of major household appliances.  The carrier must be approved
       by the Company.

       Items paid for and not paid for under this policy are as follows:

<TABLE>
<CAPTION>

          Covered                                Not Covered
          -------                                ----------- 
          <S>                                    <C>
          One Automobile (Second car             Boats
          may be moved by the employee           Lumber
          at the reimbursable rate in            Trailers
          effect for employee's use of           Cleaning Services at either location
          his/her own automobile (see            Workshops outside the residence
          Policy D.3.)                           Pets not normally
          Furnishings and Clothing kept          Household Pets e.g., horses
          in the house

</TABLE>

C.   Temporary Storage - (approval in advance)
     -----------------

       In cases  where  moves  from old to new  residence  cannot be  reasonably
       coordinated  to occur  directly,  arrangements  can be made for temporary
       storage of household goods for a period of no more than 60 days.

D.   Movement/Relocation of Family
     -----------------------------

       1. Transportation - (if applicable)  of  the employee  and his/her family
          to the new residence should be by the most reasonable and direct means
          available  such  as  family  automobile  or  economy-class   scheduled
          airliner. Meals in route are also expected to be reasonable in cost.

       2. Temporary  Living - If the new  residence is  not ready to receive the
          family,   the  Company  will  reimburse   temporary  living  expenses,
          including  medium  priced  hotel and  meals,  for a period of up to 14
          days.

E.   Temporary living - Employee Only at New Location -
     ------------------------------------------------

       When the employee takes up an assignment at the new location prior to the
       arrival of his/her family and/or before  his/her new permanent  residence
       is ready for  occupancy,  the Company  will  reimburse  the  employee for
       approved living  accommodations for a period of up to 90 days,  including
       lodging, breakfast and evening meals.

       During such time period,  the Company will pay for periodic trips home by
       the employee, the frequency depending on the travel costs involved.

<PAGE>
F.   Duplicate Housing Expense -
     -------------------------

       If the  employee  occupies  his/her  new  residence  prior to the sale of
       his/her prior residence,  the Company will reimburse the monthly carrying
       charge on such prior residence to the following extent:

       1. Monthly  reimbursable  duplicate  expenses including interest charges,
          insurance,   property  taxes  and  reasonable  maintenance  costs  for
          utilities, grass cutting, etc.

       2. The maximum period for such reimbursement is limited to 90 days.

G.   Closing Costs -
     -------------

       1. Prior Residence (Grade 15 & Above)
          ---------------     

          The Company will pay for closing costs on the disposition of the prior
          residence  consistent  with practices in the geographic area regarding
          the type and amount of such expenses  normally assigned to the seller.
          Such closing costs can include, but are not limited to:

          a.  Lawyer's Fees (up to a maximum of 1% of the old mortgage)
          b.  Realtor's Fees
          c.  Termite Inspection
          d.  Points----(up to a maximum of 2)----Assigned to Seller
          e.  Mortgage Prepayment Penalty, Specified in the Mortgage
          f.  Title search
          g.  Recording Fees

Guaranteed  home sales  plan.  Employees  may elect to sell their  homes using a
"guaranteed sale plan". Through this plan, a relocation management firm retained
by the company will provide  employees  important  assistance in connection with
their home sales.  All fees charged by the relocation firm for its services will
be assumed by the company subject to the relocation cap.

The  relocation  management  firm will make a purchase  offer valid for 60 days.
This offer is based on the  appraised  fair market value (FMV) of the  employees
home.  The FMV of the  property  will be based on the average of the  appraisals
performed by the relocation firm. If required,  the employee can request another
appraisal firm, agreeable to both the company and the employee. The company will
assume the cost of the appraisals.

During the 60 day period,  if the employee is able to sell his or her house at a
higher  price than  appraised,  he or she may assign the sale to the  relocation
management  firm and receive  equity based on the higher price.  If the employee
sells the home to the  relocation  firm, he or she will receive  equity based on
the offer price (determined by the appraisals previously discussed).

If the employee  assigns an offer to the relocation  management firm, as soon as
any  contingencies  contained in the  assigned  sale  contract are removed,  the
employee will receive full equity based on the amended or higher sale price. The
firm  will  then  assume  all the  responsibilities  of the  employee-homeowner,
including sale closing.  If the sale  subsequently  falls through,  the employee
retains  full  equity  - and  the  property  remains  in the  relocation  firm's
inventory for resale.

If the property is purchased with an assumable  mortgage,  the  relocation  firm
will  indemnify  and hold  harmless the employee from any claim or loss due to a
valid  deficiency  judgment  against  the  employee  that may  arise  out of the
continuing liability under such mortgage. The indemnification  remains in effect
for the life of the loan, notwithstanding subsequent resales by property owners.

<PAGE>
By selling or assigning a sale to the  relocation  firm,  the employee  receives
equity  when he or she  needs it (to  apply to a new  home  purchase  in the new
location) and avoids paying additional income taxes on reimbursed expenses.

       2. New Residence -
          -------------

          The Company  will also  directly  reimburse  the  employee for closing
          costs  normally  borne by the purchaser  when  purchasing  his/her new
          primary residence. Such closing costs can include, but are not limited
          to:

           a.  Title Search
           b.  Lawyer's Fees (up to a maximum of 1% of the new mortgage)
           c.  Points (up to a maximum of 2)
           d.  Inspections
           e.  Appraisals
           f.  Application Fee
           g.  Recording fee
           h.  State and local transfer taxes

H.   Termination of Lease at Prior Residence -
     ---------------------------------------

       If the  employee  resided  in a leased  or rented  property  prior to the
       transfer and must terminate or "break" the lease, the Company expects the
       employee  to  negotiate  a  reasonable   arrangement  with  the  landlord
       acceptable  to the Company,  at which point the Company will agree to pay
       the cost of any lease termination/breaking.

I.   Gross-up Payment for Tax Purposes -
     ---------------------------------
  
       Under  Federal  and State  tax laws in  existence  at the  time,  certain
       reimbursements  and payments  made to the employee or on his behalf under
       this policy may be considered taxable income.

       Deductible  and  non-deductible  moving  expense  reimbursements  will be
       included in an  employee's  taxable  income  under the category of "other
       earnings". Deductible expenses must be deducted from an employee's income
       when filing a federal tax return.  Non-deductible  expenses will be taxed
       as normal income.  Since  expenses vary from employee to employee,  these
       payments will be handled on an individual basis.

J.     General  Rule - Relocation  costs  are generally  capped by the  Company.
       Cumulative  expenses  shall  not  exceed  this  cap,  regardless  of  the
       individuals  requirements  and  costs  that  may be  associated  with any
       specific expense item.

<PAGE>

                                    Exhibit A
                             -- Maximum Allowance --
<TABLE>
<CAPTION>


    SUMMARY of COVERAGES              TRANSFEREES               NEW HIRES
    --------------------              -----------               --------- 
    <S>                              <C>                     <C>   
    House-Hunting Trips              $500 Expenses           $500 Expenses
    - Up to Two Trips                $1,500 Air Fare         $1,500 Air Fare
    (three days each)

    Move Household Goods             $1,500 in State         $0 In State
    - (See Limits in Policy)         $6,000 out of State     $6,000 Out of State

    Temporary Storage                $500    (a)
    Up to 60 Days                    $2,500  (b)             $2,500   (b)
    (Need approval in advance)

    Transportation of Employee &     $250  Expenses          $250  Expenses
    Family  (See Limits in Policy)   $1,500 Air Fare         $1,500 Air Fare

    Temporary Living                 $1,500                  $1,500   (b)
    - Up to 14 Days

    Temporary Living
    (Employee Only)                  $6,800                  $6,800
    - Up to 90 Days

    Duplicate Housing                $3,500  (a)
    - Up to 90 Days                  $7,500  (b)             $7,500   (b)

    Closing Costs-Prior Residence    $15,000 (a)
    - (See Limits in Policy)         $20,000 (b)             $20,000 (b)

    Closing Costs-New Residence      $10,000 (a)             $10,000 (a)
    - (See Limits in Policy)         $15,000 (b)             $15,000 (b)

    Terminating Lease                $2,000                  $2,000  (b)
    - (See Limits in Policy)

    Gross-Up Payments-Estimated      $15,000 (a)             $15,000 (a)
    - (See Limits in Policy)         $25,000 (b)             $25,000 (b)

(a) Up to Grade 15                   (b) Grade 15 & above

    Probable Costs:
    Up to Grade 15:                  $58,000 $45,000
    Grade 15 and Above:              $80,000 $80,000

</TABLE>

III. PRACTICES
     ---------

       Generally  speaking,  relocation expenses will be capped. The cap will be
       directly  related  to  the  position  being  filled  and  established  in
       conjunction  with II. A. (above)  prior to extending a relocation  offer.
       The maximum allowance values are for company budgeting  purposes of these
       specific items,  and do not reflect nor are they intended to suggest that
       the  employee is  authorized  to commit or incur these  expenses  without
       satisfying Part Ia (above) for each part III section.

<PAGE>
       The following  items will be paid for or reimbursed as described  herein.
       Coverages are summarized in Exhibit "A" to this policy and are contingent
       on Section II A.

<TABLE>
<CAPTION>

     SUMMARY of COVERAGES                TRANSFEREES               NEW HIRES
     <S>                                     <C>                <C>      
     House-Hunting Trips
     - Up to Two Trips                        X                        X
      (three days each)

     Move Household Goods
     - (See Limits in Policy)                 X                        X


     Temporary Storage
     - Up to 60 Days                          X                 Grade 15 & Above


     Transportation of Employee & Family
     - (See Limits in Policy)                 X                        X


     Temporary Living
     - Up to 14 Days                          X                        X

     Temporary Living  (Employee Only)
     - Up to 90 Days                          X                        X

     Duplicate Housing
     - Up to 90 Days                          X                 Grade 15 & Above

     Closing Costs - Prior Residence
     - (See Limits in Policy)                 X                 Grade 15 & Above

     Closing Costs -  New Residence
     - (See Limits in Policy)                 X                        X

     Terminating Lease
     - (See Limits in Policy)                 X                 Grade 15 & Above

     Gross-Up Payments
     - (See Limits in Policy)                 X                        X


</TABLE>

<PAGE>
                                                                     Exhibit D
                                                                     --------- 


                                    AGREEMENT
                                    ---------

         THIS  AGREEMENT,  made  this  October  1,  1996 by and  between  DIANON
SYSTEMS,   INC.,   its   affiliates,   subsidiaries,   successors   and  assigns
(collectively  called hereinafter  "DIANON") and David Schreiber,  an individual
residing at 1780 Nicholson Drive,  Hoffman Estates,  Illinois 60192 (hereinafter
called "Employee").

         In  consideration  of the  commencement  of Employee's  employment with
DIANON, the payment of compensation and benefits for such employment, and access
to sensitive information,  Employee and DIANON acknowledge,  represent and agree
to the terms and conditions set forth in this Agreement.

         1.  Employee's  employment  with DIANON creates a relationship of trust
and  confidence  between the parties.  Employee  agrees  that,  during and after
his/her  employment  with DIANON,  Employee  will not use or disclose,  or allow
anyone else to use or disclose,  any  confidential  information  relating to the
products, sales and/or business affairs of DIANON or of any customer or supplier
of DIANON,  or any  information  created,  discovered,  or  developed  by or for
DIANON, or acquired by DIANON,  that has commercial value in DIANON's present or
future business ("Confidential Information"),  except as may be necessary in the
performance  of  Employee's  employment  with DIANON or as may be  authorized in
advance by  appropriate  officials of DIANON.  By way of  illustration,  but not
limitation,   Confidential  Information  includes  processes,   formulas,  data,
know-how, inventions,  improvements,  techniques, marketing plans, product plan,
strategies,  forecasts,  customer lists and any other  information  Employee has
reason to know  DIANON  would  like to treat as  confidential  for any  purpose.
Employee  agrees to keep  Confidential  Information  secret  whether  or not any
document containing such information is marked confidential.

         2. All rights, title and interest in all records,  documents,  or files
concerning the business of DIANON,  including,  but not limited to biomaterials,
processes,  letters,  trade  secrets,  laboratory  notebooks or other written or
electronically recorded material, whether or not produced by the Employee, shall
be and remain the  property  of DIANON.  Upon  termination  of  employment,  the
Employee shall not have the right to remove any such records from the offices of
DIANON. In addition,  Employee agrees to promptly return to DIANON all things of
whatsoever  nature that belong to DIANON,  and all records (in whatsoever  form,
format or medium) contained or related to Confidential Information of DIANON.

         3. Employee agrees to assign,  and does hereby assign to DIANON, all of
his/her  right,  title  and  interest  in and to all  inventions,  improvements,
discoveries or technical developments,  whether or not patentable,  which he/she
solely or jointly  with others,  may  conceive or reduce to practice  during the
term of his/her  employment (a) which are related in whole or in part,  directly
or indirectly,  to DIANON's product line, research and development,  or field of
technological or industrial specialization,  or (b) in the course of utilization
by DIANON of Employee's services in a technical or professional  capacity in the
areas  of  research,   development,   marketing,   management,   engineering  or
manufacturing,  or (c)  pursuant  to any  project of which  Employee is or was a

<PAGE>
participant or member that is or was either  financed or directed by DIANON,  or
(d) at DIANON's expense, in whole or in part.

         4. Employee  agrees to disclose  promptly to DIANON's  President or his
designee, all ideas,  discoveries,  and improvements conceived by Employee alone
or in collaboration with others, and to cooperate fully with DIANON, both during
and after  employment,  with  respect  to the  procurement  of  patents  for the
establishment and maintenance of DIANON's or its designee's rights and interests
in said invention,  improvement,  discoveries or  developments,  and to sign all
papers which DIANON may deem  necessary or desirable  for the purpose of vesting
DIANON or its  designees  with such rights,  the expenses  thereof to be paid by
DIANON.

         5. The Employee  shall,  while employed by DIANON,  devote his/her best
efforts and his/her full time to the business of DIANON.

         6. In the event of a breach or threatened  breach of the  provisions in
this  Agreement,  DIANON  shall be entitled to an  injunction  restraining  such
breach,  it being  recognized  that any injury  arising  from a breach  would be
irreparable  and could have no adequate  remedy at law; but nothing herein shall
be construed as prohibiting  DIANON from pursuing any other remedy available for
such  breach or  threatened  breach.  In the event  that  Employee  breaches  or
threatens  a breach of this  Agreement,  DIANON  shall be  entitled  to have its
reasonable  legal fees and costs  paid by the  Employee  for any legal  services
relating to the breach or threatened breach.

         7. This  Agreement is not intended,  and should not be construed in any
way, as a contract of  employment  for a definite  period of time or to limit or
restrain   DIANON's  or  the  Employee's   right  to  terminate  the  employment
relationship at any time.

         8. In the  event  any  provision  or  paragraph  of this  Agreement  is
declared to be invalid or unenfoceable, then the balance of this Agreement shall
remain in full force and effect.

         9. This  Agreement  shall be construed and enforced in accordance  with
the laws of the State of Connecticut.

         10. The  foregoing  contains the entire  Agreement  between the parties
pertaining to confidential  DIANON  documents and  information.  No modification
thereof shall be binding upon the parties unless the same is in a writing signed
by the  respective  parties.  This Agreement and all of the terms and conditions
contained  herein  shall  remain in full force  during the period of  employment
notwithstanding any changes in compensation.

         11.  Employee   represents  and  warrants  that  he/she  has  no  other
agreements or  commitments  that would hinder or prevent  performance of his/her
job  responsibilities  with DIANON.  Unless authorized to do so, Employee agrees
not to disclose to DIANON or use in his/her employment with DIANON any invention
or  confidential  information  belonging to any former  employer or to any other
person other than DIANON.

<PAGE>
         IN WITNESS WHEREOF,  the parties have entered into this Agreement as of
the date set forth below.


Employee:                                   DIANON SYSTEMS, INC.


/s/ David Schreiber                         By: /s/ Kevin C. Johnson
- -------------------                             ------------------------
David Schreiber                                 Kevin C. Johnson

Dated: 10/1/96                              Dated: September 30, 1996
       -------                                     ---------------------


<TABLE> <S> <C>

<ARTICLE>                5
<MULTIPLIER>             1,000
<CURRENCY>               U.S. Dollars
       
<S>                                                                 <C>
<PERIOD-TYPE>                                                       9-MOS
<FISCAL-YEAR-END>                                                   DEC-31-1996
<PERIOD-START>                                                      JAN-01-1996
<PERIOD-END>                                                        SEP-30-1996
<EXCHANGE-RATE>                                                               1
<CASH>                                                                    5,961
<SECURITIES>                                                                  0
<RECEIVABLES>                                                            12,491
<ALLOWANCES>                                                                787
<INVENTORY>                                                                 634
<CURRENT-ASSETS>                                                         21,301
<PP&E>                                                                   15,737
<DEPRECIATION>                                                            8,027
<TOTAL-ASSETS>                                                           30,132
<CURRENT-LIABILITIES>                                                     7,104
<BONDS>                                                                       0
                                                         0
                                                                   0
<COMMON>                                                                     63
<OTHER-SE>                                                               22,824
<TOTAL-LIABILITY-AND-EQUITY>                                             30,132
<SALES>                                                                  13,863
<TOTAL-REVENUES>                                                         13,863
<CGS>                                                                     6,800
<TOTAL-COSTS>                                                             6,800
<OTHER-EXPENSES>                                                          5,944
<LOSS-PROVISION>                                                              0
<INTEREST-EXPENSE>                                                           18
<INCOME-PRETAX>                                                           1,152
<INCOME-TAX>                                                                495
<INCOME-CONTINUING>                                                         657
<DISCONTINUED>                                                                0
<EXTRAORDINARY>                                                               0
<CHANGES>                                                                     0
<NET-INCOME>                                                                657
<EPS-PRIMARY>                                                              0.10
<EPS-DILUTED>                                                              0.10
        


</TABLE>


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