DIANON SYSTEMS INC
10-K, 1997-03-31
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 10-K

                 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                  For the fiscal year ended December 31, 1996
                        Commission file number 000-19392

                              DIANON Systems, Inc.
                              --------------------
              (Exact Name of Registrant as Specified in its Charter)

          Delaware                                             06-1128081
          --------                                             ----------
  (State or Other Jurisdiction of                            (I.R.S. Employer
  Incorporation or Organization)                            Identification No.)

200 Watson Boulevard, Stratford, Connecticut                     06497
- --------------------------------------------                     -----
 Address of Principal Executive Offices)                       (Zip Code)

Registrant's telephone number, including area code  (203) 381-4000
                                                    --------------
         
Securities registered pursuant to Section 12(b) of the Act:

                                                  Name of Each Exchange on
    Title of Each Class                                Which Registered
    -------------------                           ------------------------

           None                                            None

Securities registered pursuant to Section 12(g) of the Act:

                     Common Stock, par value $.01 per share
                     --------------------------------------
                                (Title of Class)

Number of shares of Common Stock outstanding as of March 14, 1997:  6,449,270

INDICATE BY CHECK MARK WHETHER THE REGISTRANT (1) HAS FILED ALL REPORTS REQUIRED
TO BE FILED BY SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 DURING
THE  PRECEDING 12 MONTHS (OR FOR SUCH  SHORTER  PERIOD THAT THE  REGISTRANT  WAS
REQUIRED  TO FILE  SUCH  REPORTS),  AND  (2) HAS  BEEN  SUBJECT  TO SUCH  FILING
REQUIREMENTS FOR THE PAST 90 DAYS. YES [X] NO [ ]

INDICATE BY CHECK MARK IF DISCLOSURE OF DELINQUENT  FILERS  PURSUANT TO ITEM 405
OF REGULATIONS S-K IS NOT CONTAINED  HEREIN,  AND WILL NOT BE CONTAINED,  TO THE
BEST OF REGISTRANT'S  KNOWLEDGE,  IN DEFINITIVE PROXY OR INFORMATION  STATEMENTS
INCORPORATED BY REFERENCE IN PART III OF THIS FORM 10-K OR ANY AMENDMENT TO THIS
FORM 10-K. [ ]

As of March 14, 1997, the aggregate market value of the voting Common Stock held
by non-affiliates of the registrant was $54,818,795.

                       Documents Incorporated By Reference
                                      None


                      EXHIBIT INDEX ON PAGE 55 OF 133 PAGES

<PAGE>

                                     PART I
ITEM 1.  BUSINESS

         DIANON  Systems,  Inc.  ("DIANON"  or the  "Company")  is a provider of
anatomic  pathology  and  clinical  chemistry  testing  services to  physicians,
patients and managed care organizations across the United States.

         Historically,  the Company  has been a  specialized  laboratory  with a
limited line of clinical chemistry and anatomic pathology testing services based
principally on new technology  purchased or licensed from test developers.  This
technology has been marketed  directly to medical  oncologists and urologists as
testing and information services rather than as products or test kits.

         As a result of the Company's success in providing  pathology  services,
the mission of the Company has been  expanded to include a full line of anatomic
pathology services and related information products to physicians,  patients and
managed care organizations throughout the United States. The Company's principal
physician audience for these services includes  approximately  50,000 clinicians
engaged in the fields of medical oncology, urology, dermatology,  gynecology and
gastroenterology.  The  Company  believes  it can  become  one  of  the  leading
specialized  providers  of  anatomic  pathology  testing  services in the United
States.

         While  the  Company  continues  in its  traditional  role of  assisting
developers of new technology and physicians  evaluating such  technology,  it is
expected that this activity and the Company's  clinical  chemistry business will
represent a decreasing  proportion  of total revenue in future years as anatomic
pathology revenues grow.

         The  business  of the  Company  is  subject  to a number  of risks  and
uncertainties  that could adversely affect the Company's  ability to achieve its
objectives.  See "Management's  Discussion and Analysis of Results of Operations
and  Financial  Condition - Risk  Factors:  Forward  Looking  Statements"  for a
description  of  various  factors  that  could  have an  adverse  effect  on the
performance of the Company.

Medical Testing Markets

         Medical  laboratories  offer a broad  range of testing  services to the
medical  profession.  These  testing  services  are  used by  physicians  in the
diagnosis,  prognosis,  monitoring and general  management of diseases and other
clinical conditions.  The tests they use generally detect medically  significant
abnormalities and visual patterns in blood, tissue samples and other specimens.

         Management  divides  the  market  for  medical  testing  into  anatomic
pathology  testing  and  clinical  chemistry  testing  and has set forth in very
general terms some of the major differences between them in the table below:

<TABLE>
<CAPTION>
                                   Anatomic Pathology Testing                   Clinical Chemistry Testing
                                   --------------------------                   --------------------------

<S>                           <C>                                          <C>
Type of Specimen              Tissue or cells - usually obtained by        Blood or urine - usually collected by
                              a physician from a biopsy, Pap smear,        a nurse (blood) or by the patient (urine)
                              urine specimen or surgery                     

Technology Employed           Physician interpretation of tissue           Highly automated blood chemistries and
                              slides supplemented by special antibody      immunoassays
                              stains, DNA probes, genetic tests

1991 DIANON Net Revenues      $ 9 million                                  $18 million

1996 DIANON Net Revenues      $37 million                                  $19 million
</TABLE>


<PAGE>

         The  Company  offers a  complete  line of  anatomic  pathology  testing
services  as  well  as  selected   clinical   chemistry  tests  for  cancer  and
gynecological conditions.  The Company performs all testing at its main facility
in Stratford,  Connecticut  and provides most test results to physicians  within
forty-eight hours. In 1996 the Company opened a specimen  processing facility at
the hub of its airfreight provider in Ohio in order to prepare certain specimens
for more rapid  processing  when they arrive in Stratford and to improve overall
turnaround  time to the  physicians.  No test accounted for more than 20% of net
revenues in 1996.

Information Services

         The Company's  information  services are used principally to assist the
physician in the analysis of test results and to help managed care organizations
better manage patient  treatment.  Patient specific reports aid the physician in
analyzing  multiple  prognostic tests and/or  correlative  trends in a patient's
test results, treatment, and clinical condition. Summary reports on all patients
in a  physician's  practice  allow the  physician  to  compare  test  results on
patients with similar conditions, review multiple patient histories, and compare
his or her  experience  with that of  physicians  across  the  country.  Similar
reports help  managed care  organizations  capture and compare  utilization  and
diagnostic  trends  within  their own  organization,  with  other  managed  care
organizations and with the Company's  national  database.  The Company's current
information  services are an important part of the Company's  marketing program,
and while they do not specifically  generate  revenue they do provide  important
value-added   services  which  help  the  Company   differentiate   itself  from
competitors.

Quality Assurance

         The Company's quality assurance program includes adherence by employees
to  the  Standard  Operating  Procedures,  continuing  education  and  technical
training  of  technologists,  statistical  quality  control  of  all  analytical
processes,  instrument  maintenance,  and  regular  inspection  by  governmental
agencies and the College of American Pathologists.

         The Company  utilizes a unique  quality  control  program for  anatomic
pathology  which  provides a reduced  number of  equivocal  results  reported to
clinicians.  This program is applied to all  anatomic  pathology  specimens.  By
diminishing  the  number  of  equivocal  diagnoses  and  providing  the  correct
diagnosis as soon as possible,  the Company enables clinicians to treat patients
sooner and more effectively and to reduce overall health care costs.

European Operations

         In recent years the Company has been  engaged in a  diagnostic  testing
business  in Europe,  principally  in Germany  and Spain.  In 1995,  the Company
decided  to sell or close its  European  operations  and  provided  a reserve of
approximately  $279,000 to cover the costs of doing so.  Remaining  reserves for
the  discontinuance  of  operations  at  December  31,  1996  are  approximately
$155,000.  The  Company is in the  process of  liquidating  the  European  based
operations and plans to complete the liquidation  process by the end of the 1997
fiscal year.

Reimbursement

         In 1996, 1995, and 1994 approximately 40%, 41%, and 34%,  respectively,
of  the  Company's  net  revenues  were  derived  from  testing   performed  for
beneficiaries  under the Medicare and Medicaid  programs,  substantially  all of
which was derived from the Medicare program. Revenues from testing performed for
other patients are derived principally from other third-party payors,  including
commercial  insurers,  health maintenance and preferred provider  organizations,
patients,  physicians,  hospitals,  and other  laboratories (who in turn usually
bill non-governmental third-party payors or patients). In each of 1996, 1995 and
1994,  less  than  10%  of the  Company's  revenues  were  derived  from  health

<PAGE>

maintenance  organizations with whom the Company has contracts.  For many of the
tests  performed  for  Medicare  or  Medicaid   beneficiaries  (except  clinical
diagnostic  laboratory tests for those individuals being treated by a hospital),
laboratories  are  required to bill  Medicare or Medicaid  directly  for covered
services and to accept Medicare or Medicaid reimbursement as payment in full for
such services.  Management has elected,  to date, to accept  reimbursement rates
set by other  third-party  payors as payment in full (apart from any  co-payment
which the payor has established) as well.

         Reimbursement  rates for some  services  of the type or  similar to the
type performed by the Company have been  established  by Medicare,  Medicaid and
other third-party  payors,  but have not been established for all services or by
all  carriers  with  respect to any  particular  service.  While most  carriers,
including Medicare,  do not cover services they determine to be investigational,
or otherwise not reasonable  and necessary for diagnosis or treatment,  a formal
coverage  determination  is made with respect to relatively few new  procedures.
When such determinations do occur for Medicare purposes,  they most commonly are
made by the local  Medicare  carrier which  processes  claims for  reimbursement
within the carrier's  geographic  jurisdiction.  The Company  receives  Medicare
reimbursement  primarily through a single Medicare carrier.  A positive coverage
determination,  or  reimbursement  without  such  determination,  by one or more
third-party  payors, or clearance for market by the Food and Drug Administration
("FDA"),  does not  assure  reimbursement  by other  third-party  payors.  A few
third-party  payors  have  denied  payment  for  services  for which the Company
receives  reimbursement  from  other  payors.  On  occasion,  Medicare  or other
third-party  payors  have  decided  to  cease  payment  for  one or  more of the
Company's  services that  historically have been reimbursed by them because such
services are performed using test kits or other products which have not received
FDA  pre-market  clearance  or because  such  services  may  otherwise be deemed
investigational   or  for  other  reasons.   Furthermore,   Medicare  and  other
third-party  payors have, on occasion,  ceased  reimbursement when certain tests
are ordered for patients with certain diagnoses while maintaining  reimbursement
when such  tests are  ordered  for other  diagnoses  deemed  appropriate  by the
carrier.  This  practice  recently  has become more  prevalent  with  respect to
Medicare.  Reimbursement  disapprovals  by the various  carriers,  reductions or
delays in the  establishment of reimbursement  rates, and crrier  limitations on
the insurance  coverage of the Company's  services could have a material adverse
effect on the Company's future revenues.

         Medicare  Fee  Schedule  Payment  for  Clinical  Chemistry   Laboratory
Services. In 1984, Congress adopted legislation establishing a locality-specific
fee schedule reimbursement methodology with Consumer Price Index ("CPI")-related
updates for clinical diagnostic laboratory testing for non-hospital patients and
hospital out-patients under Medicare. (Payment for clinical chemistry laboratory
services performed for Medicare in-patients is included within the prospectively
determined  Diagnosis  Related  Group rate paid to the  hospital.)  In addition,
state Medicaid  programs are  prohibited  from paying more than the Medicare fee
schedule amount.  Beginning with the consolidated Omnibus Budget  Reconciliation
Act of 1985  ("OBRA  '85"),  Congress  instituted  a  national  cap on  Medicare
clinical chemistry laboratory fee schedules.  This national cap has been lowered
each year and now is 76% of the national median. In addition, the Omnibus Budget
Reconciliation Act of 1987 ("OBRA '87"), eliminated the CPI update for 1988 and,
in succeeding years,  Congress has often either limited or eliminated the annual
CPI updates of the Medicare clinical  chemistry  laboratory fee schedules.  Most
recently,  the Omnibus Budget Reconciliation Act of 1993 ("OBRA '93") eliminated
the update  for the years  1994 and 1995.  In 1996,  however,  the fee  schedule
update was 3.2%; the Health Care Financing  Administration ("HCFA") has recently
announced  that the fee  schedule  update  for 1997 will be 2.7%.  However,  the
corresponding  expected  national cap increase of 2.7% may not be fully realized
due to a recalculation  of national  medians  necessitated by conversion in some
carrier areas to a single  statewide fee schedule.  The update  limitations  and
changes in the  national  cap made to date have not had, and are not expected by
the  Company to have,  a material  adverse  effect on the  Company's  results of
operations.  Any further  significant  decrease in such fee schedules,  however,
could have a material adverse effect on the Company.


<PAGE>

         Any  future   changes  in  government  and  other   third-party   payor
reimbursement  which may come about as a consequence of enactment of health care
reform or of  deficit  reduction  legislation  also  likely  will  continue  the
downward pressure on prices and make the market for clinical laboratory services
more competitive. The Medicare proposal contained in the President's fiscal year
1998  budget  offers an  indication  of the  direction  future  Medicare  reform
legislation  may  take  with  respect  to  clinical  laboratory  services.   The
President's  proposed  budget  would not modify  the  national  cap on  Medicare
clinical  chemistry  laboratory  fee  schedules  or  eliminate  annual  updates;
however,   it  would  establish   competitive  bidding  for  clinical  chemistry
laboratory services. If the President's proposal failed to realize savings of at
least  20% for a  given  year  through  the  competitive  bidding  process,  the
Secretary of the  Department of Health and Human  Services  ("HHS") would reduce
Medicare's  fees for  laboratory  services  to achieve  this  targeted  savings.
Furthermore,  the  President's  support for  competitive  bidding has  rekindled
efforts in the HCFA to  initiate a  Medicare  demonstration  project to test the
savings  potential  of  competitive  bidding  for  Part  B  clinical  laboratory
services,  which  include  the type of  services  provided  by the  Company.  If
ultimately  adopted through  legislation,  these proposals  likely would have an
adverse impact on the Company's revenues.

         Moreover,  the Congress has voiced concern that the President's  budget
does not yield  sufficient  savings to balance the budget in 2002.  As a result,
the Congress may propose additional savings measures, especially in the Medicare
program.  H.R.  2491,  the Balanced  Budget Act of 1995,  passed by Congress and
vetoed by  President  Clinton  in  December  1995,  offers  some  indication  of
additional  savings  measures that Congress may propose in the future.  Although
H.R. 2491 would not have established  competitive bidding for clinical chemistry
laboratory  services,  it instead  proposed that a fail-safe budget mechanism be
used if projected  savings were not realized in Medicare  service  expenditures.
This fail-safe  mechanism might have further reduced  reimbursement for Medicare
clinical chemistry  laboratory  services and physician  services  (including the
Company's anatomic pathology service). In addition, H.R. 2491 would have further
reduced the national cap on Medicare clinical chemistry laboratory fee schedules
to 65% of the national median in 1997. It also would have eliminated  annual CPI
updates in the Medicare clinical chemistry laboratory fee schedules until fiscal
year 2002.

         Both the Medicare  proposal  contained in the  President's  fiscal year
1998 budget and H.R.  2491 would revise the Medicare  program  substantially  to
permit beneficiaries to choose between traditional  fee-for-service Medicare and
several  non-traditional  Medicare  options,  including  managed  care plans and
provider-sponsored  organization  plans.  These  non-traditional  Medicare plans
would have considerable  discretion in determining  whether and how to cover and
reimburse  clinical  laboratory  services  and to limit the  number of labs with
which they deal. Although neither proposal would require Medicare  beneficiaries
to pay 20% of the fee for  each  clinical  laboratory  service,  nothing  in the
proposals would prohibit non-traditional Medicare plans from implementing such a
requirement.

         The Medicare  proposal  contained in the  President's  fiscal year 1998
budget  also  contains  measures to  establish  market-oriented  purchasing  for
Medicare,   including  prospective  payment  systems  for  out-patient  hospital
services,  home  health  care,  and  nursing  home  care,  and the use of global
payments and flexible  purchasing.  Although the details of these  proposals are
yet to be developed,  if implemented,  they probably would increase  pressure on
pricing in the clinical  laboratory  industry and may have an adverse  impact on
the Company's revenues.


<PAGE>

         Medicare  changes  along the lines  described  above are possible  this
year.  Because of the uncertainties  about the exact nature of any changes which
may ultimately be adopted,  however,  the Company currently is unable to predict
their ultimate impact on the clinical  laboratory  industry  generally or on the
Company in particular.  Even apart from federal legislative action,  reforms may
occur at the state level and  changes  are  occurring  in the  marketplace  as a
result of market pressures,  including the increasing number of patients covered
by some form of managed  care.  In  general,  these  changes are likely to put a
downward  pressure  on  price,  and  may  also  act  to  limit  access  by  some
laboratories to some managed care patient groups.  Because of the  uncertainties
about the exact nature,  extent,  and timing of any such changes,  however,  the
Company  currently is unable to predict  their  ultimate  impact on the clinical
laboratory industry generally or on the Company in particular.

         Medicare  Payment  for  Anatomic  Pathology  Services.  In  addition to
furnishing clinical chemistry laboratory testing services, the Company furnishes
a number of services  which are  characterized  for the purposes of the Medicare
program  as  anatomic  pathology  services.  Medicare  reimbursement  for  these
services  constituted  approximately  30%,  26%,  and 18% of the  Company's  net
revenues  in 1996,  1995,  and 1994,  respectively.  As of January 1, 1992,  all
physician services,  including anatomic pathology services, have been reimbursed
by Medicare based on a methodology  known as the  resource-based  relative value
scale ("RBRVS"), which was fully phased in by the end of 1996. Overall, anatomic
pathology  reimbursement rates declined during the fee schedule phase-in period,
despite an increase in payment rates for certain pathology services performed by
the Company.

         The  Medicare   RBRVS   payment  for  each  service  is  calculated  by
multiplying the total relative value units ("RVUs")  established for the service
by a conversion  factor that is set by statute.  The number of RVUs  assigned to
each  service  is in  turn  calculated  by  adding  three  separate  components,
including one representing  the relative work values.  In 1996, HCFA completed a
five-year review of the work value component and, as a result,  revised the work
value  amount  assigned to many  physician  services.  In  addition,  based on a
default  formula  established  by  statute,   the  1997  conversion  factor  for
nonsurgical  services dropped 0.8% from 1996 to $33.8454 per conversion  factor.
The changes  resulting from the five-year  review,  combined with the conversion
factor  reductions,  resulted  in an  overall  decrease  in  payment  rates  for
pathology  services of approximately  5.7% beginning January 1, 1997. Also, HCFA
reduced the number of physician fee schedule payment  localities from 210 to 89,
effective January 1, 1997.  Connecticut was one of the states that HCFA moved to
a single payment locality.  This modification resulted in a 3.2% decrease in the
RBRVS   geographic   adjustment   factor  for  physicians   located  in  Western
Connecticut, where the Company's primary operations are located.

         In the past, the Company has been able to offset a substantial  portion
of the impact of the reduced Medicare reimbursement rates for anatomic pathology
services  through the achievement of economies of scale and the  introduction of
alternative technologies that will not depend on reimbursement through the RBRVS
system.  Despite these offsets,  the substantial  modifications to the physician
fee  schedule  effective  January  1, 1997,  may have a  negative  effect on the
Company's average unit price.

         Furthermore, as a result of the Social Security Act amendments of 1994,
Medicare is required to revise the formula for calculating the practice  expense
component of the physicians'  Medicare fee schedule from the current  historical
basis to a resource basis  beginning  January 1, 1998. In order to complete this
task,  HCFA  hired a  consultant  to survey  some  5,000  practices  to  collect
aggregate  practice  expense data.  Although HCFA terminated the survey due to a
low response  rate,  the agency  maintains that it still can meet its mandate to
implement a  resource-based  practice  expense  component by January 1, 1998, by
using  existing  data.  Some concern has been  expressed by physician  specialty
groups that this data is not adequate and that the methodology  being used could
result in specialty practice expenses being underestimated.  At this point, HCFA
is considering a variety of options for calculating  practice expense revisions.
It is possible  that certain  changes  HCFA might make would have a  significant
negative affect on  reimbursement  for anatomic  pathology  services,  including
services furnished by the Company.


<PAGE>

         With respect to potential  legislative  changes, the Medicare proposals
contained in both the President's fiscal year 1998 budget and in H.R. 2491 would
implement a single  conversion  factor for  physician  services.  In 1998,  this
single  conversion  factor  would  likely be  slightly  higher  than the current
conversion  factor for  pathologists.  If enacted,  this  increase may favorably
affect or, more  likely,  offset to some degree the adverse  impact of the other
developments  described above on revenues from the Company's physician pathology
services.  However,  the Company is not able to predict the exact  nature of any
legislative changes affecting anatomic pathology services reimbursement, and the
Company therefore currently is unable to predict the ultimate effect of any such
changes on the Company.

         Other Developments Affecting Reimbursement.  In 1996, approximately 16%
of the Company's net revenues were in the State of New York. In September  1996,
New York  passed the New York Health  Care  Reform Act of 1996  ("NYHCRA").  The
NYHCRA  requires  payors to pay an 8.18%  surcharge  on  services  provided by a
variety of providers including independent laboratories for services rendered to
residents  of the State of New  York.  If the  payor  neglects  to pay the 8.18%
surcharge  directly,  providers  are required to collect the  surcharge  plus an
additional  assessment of 24% for a total surcharge of 32.18%. Under the NYHCRA,
it is possible that independent  labs, such as the Company,  will be placed at a
competitive  disadvantage  with  physician  office  labs and  other  labs  whose
services  are not  subject  to the  surcharge.  In  addition,  independent  labs
probably  will be liable for the  surcharge  even if the payor  fails to pay the
laboratory.  Moreover,  payors  may  reduce  the fees  they  pay for  laboratory
services  in  order  to  offset  the  surcharge.  The New  York  State  Clinical
Laboratory Association has brought suit against the New York State Department of
Health alleging that these provisions of NYHCRA are  unconstitutional  under the
United  States and New York  State  Constitutions  and  should not be  enforced.
Nonetheless,  these  changes  currently are being  implemented  and could have a
negative  impact on the portion of the Company's  net revenues  derived from the
State of New York.

         Following  a study of  pricing  practices  in the  clinical  laboratory
industry,  the Office of the Inspector  General ("OIG") of HHS conducted a study
of, and in January 1990 issued a final report relating to, such practices.  This
report  addresses how these pricing  practices  relate to Medicare and Medicaid.
The OIG reviewed the industry's use of one fee schedule for physicians and other
professional accounts and another fee schedule for patients/third-party  payors,
including Medicare, in billing for testing services.

         The OIG  also  specifically  reviewed  the  pricing  differential  when
profiles (or established groups of tests) are ordered.  The OIG recommended that
HCFA seek legislation that would allow adjustments in the Medicare fee schedules
to bring the fee  schedules  into line  with what the lower  price  laboratories
charge  physicians.  The OIG also recommended that when profiles are ordered for
Medicare  beneficiaries  that HCFA take necessary action  specifically to ensure
that  Medicare  benefits  from the pricing  structure  used by  laboratories  in
charging  physicians  for  profiles.   Similarly,  in  June  1991,  the  General
Accounting  Office  ("GAO")  issued a report  recommending  a  reduction  in the
national cap on Medicare fee schedules for laboratory  services to eliminate the
disparities in laboratory  pricing practices.  (This recommended  reduction - to
76% of the  national  median  - was in fact  enacted  as part of OBRA  '93.)  In
response to the GAO HCFA recommended that OIG initiate a legislative proposal to
enhance existing authority to penalize discriminatory pricing.  Existing federal
law authorizes the Secretary of HHS to exclude  providers from  participation in
the  Medicare and Medicaid  programs if they charge state  Medicaid  programs or
Medicare fees "substantially in excess" of their "usual charges". On January 29,
1992, in the preamble to a Final Rule  implementing  program exclusion and civil
money penalty  authorities  established  under the Medicare and Medicaid Patient
and Program  Protection  Act of 1987, the OIG considered but declined to provide
any standards as to when charges for a service are considered  "substantially in
excess" of a provider's  "usual charges".  However,  the OIG stated that it will
continue to evaluate the billing patterns of individuals and entities, including
clinical laboratories, on a case-by-case basis. The Medicaid laws in some states
also have prohibitions  related to discriminatory  pricing.  The Company employs
practices  similar to those examined in the 1990 OIG report  discussed  above in
billing  for its  services.  Depending  upon the  nature  of any  regulatory  or

<PAGE>

enforcement  action taken or the content of legislation,  if any, which might be
adopted to address  this  issue,  the Company  could  experience  a  significant
decreasein  revenue which could have a material  adverse  effect on the Company.
The legislation also provides for civil or criminal  penalties or exclusion from
participation in Medicare and Medicaid. The Company is unable to predict at this
time whether any further regulatory,  enforcement, or legislative action will be
taken.

         In December 1992, an unrelated  clinical  laboratory,  National  Health
Laboratories,   Inc.,  ("NHL"),  pleaded  guilty  to  submitting  false  medical
reimbursement  claims  to the  United  States  government,  and  entered  into a
settlement  which  provides for payment of over $100 million.  The United States
government  alleged that NHL, by marketing to physicians  diagnostic test panels
which bundled,  together with a routine blood chemistry series,  two other tests
(ferritin and HDL  cholesterol),  induced  physicians to order these other tests
regardless of medical necessity. While NHL's additional charge to physicians for
these two tests  ordered as part of the NHL panel was  nominal,  NHL billed this
Medicare program for them at full price.  Since 1993, several other laboratories
have reached  significant  financial  settlements  with the  government in cases
involving  similar  issues.  While it is not possible to predict how broadly the
United States government may seek to expand the theory of liability it developed
in these cases, the Company believes its practices differ  materially from those
at issue and has no reason to believe that its  practices are the subject of any
investigation in this regard.

         In  February,  1997,  the OIG  released  a model  compliance  plan  for
laboratories  that  is  based  largely  on the  corporate  integrity  agreements
negotiated  with the  laboratories  which settled the  government's  enforcement
actions.  The Company is reviewing the model compliance plan and plans to adopt,
or modify  for  adoption,  aspects  of the model  plan  that the  Company  deems
appropriate  to the  conduct of its  business.  One key aspect of the  corporate
integrity  agreements  and  the  model  compliance  plan is an  emphasis  on the
responsibilities  of laboratories to notify physicians that Medicare covers only
medically  necessary  services.  Although these  requirements,  and their likely
effect on physician test ordering habits,  focus on chemistry tests,  especially
routine tests,  rather than on anatomic  pathology services or the non-automated
tests which make up the bulk of the Company's  business,  they potentially could
affect  physician  test ordering  habits more broadly.  The Company is unable to
predict whether, or to what extent, these developments may have an impact on the
utilization of the Company's services.

Competition

         The Company provides  services in a segment of the healthcare  industry
that is extremely  competitive.  The Company's  actual or potential  competitors
include large clinical  laboratories,  special purpose clinical laboratories and
product companies that manufacture test kits and other diagnostic tools.

         The  clinical   laboratory   business  is   characterized   by  intense
competition.   The  Company  estimates  that  there  are  over  11,500  clinical
laboratories  in the United  States  which might be deemed  actual or  potential
competitors for the testing business of a cancer-treating  or  cancer-diagnosing
physician.  In the U.S.,  anatomic pathology and clinical  chemistry  laboratory
services  are  provided   through   physician-owned   laboratories,   commercial
laboratories  and hospital  laboratories.  In the U.S.,  there are several large
clinical  laboratory  companies  which  market a "full  line"  of such  services
nationally, and which have substantially greater financial,  selling, logistical
and  laboratory  resources than the Company.  These  companies  typically  offer
hundreds of different tests and management believes that these companies compete
in  general on  quality,  price and the time  required  to report  results.  The
Company estimates that the three largest national  clinical  laboratories in the
U.S.  accounted  for  greater  than  40%  of  the  total  non-hospital  clinical
laboratory market in 1996.

         In  addition,  the  Company's  management  has  identified  a number of
specialized  laboratories  in the U.S.  established  since  1987.  None of those
specialized  laboratories  have sales greater than 5% of the anatomic  pathology
market.


<PAGE>

         The Company  also  processes  specimens  from a number of  non-hospital
clinical  laboratories.  Sales to such laboratories amounted to approximately 3%
of the Company's net revenues in 1996 and 5% in 1995 and 1994.

         In  addition  to  competition   for  customers,   there  is  increasing
competition for qualified  personnel,  particularly in the laboratory.  To date,
such competition has not had an adverse impact on the Company's operations.

         Significant  factors  that  enhance  the  Company's  ability to compete
effectively include a highly trained and knowledgeable sales force, high quality
laboratory operations,  accurate and consistent test results, quality of service
to physicians, price and, to a lesser extent, speed of turnaround.

Patents and Proprietary Technology

         To date,  the  Company  has not relied  heavily on patents or  licensed
technology in its business.  Tests or related  diagnostic  products purchased by
the  Company may or may not be  patented.  There can be no  assurance  that such
tests or related  products do not infringe patent rights of others,  which could
give  rise  to  claims  against  the  Company.  Typically  the  Company  is  not
indemnified against such risks. There can be no assurance that any issued patent
upon which the Company relies directly or indirectly  will afford  protection to
the Company in the face of challenges to the patent's validity.

         Other private and public entities,  including universities,  have filed
applications  for (or have been issued)  patents in the Company's  field and may
obtain additional patents and other proprietary rights to technology that may be
the same as or similar to that  utilized by the Company.  The scope and validity
of such  patents,  the extent to which the  Company  may wish or need to acquire
such rights,  and the cost or availability of such rights are presently unknown.
There can be no  assurance  that others may not obtain  access to the  Company's
technology  or  independently  develop  the same or similar  technology  to that
utilized by the Company.

Employees

         On December 31, 1996,  the Company had 385  full-time  and 35 part-time
employees worldwide.

Regulatory Matters

         The  Company's  business is subject to  governmental  regulation at the
federal,  state and local levels,  some of which regulations are described under
"Laboratory", "Food and Drug Administration" and "Other" below.

         Laboratory

         The  Company's  laboratory  is certified or licensed  under the federal
Medicare program, the Connecticut Medicaid program and the Clinical Laboratories
Improvement  Act of 1967,  as amended  by the  Clinical  Laboratory  Improvement
Amendments of 1988 (collectively, "CLIA '88"). Licensure is maintained under the
clinical laboratory licensure laws of Connecticut,  where the Company's clinical
laboratory  is located and under the laws of several  other  jurisdictions.  The
Company believes it has obtained all material  laboratory  licenses required for
its operations.  In addition,  the laboratory is licensed by the federal Nuclear
Regulatory Commission and is accredited by the College of American Pathology.

         The federal and state  certification and licensure  programs  establish
standards for the day-to-day operation of a medical laboratory,  including,  but
not limited to, personnel and quality control. Compliance with such standards is
verified  by periodic  inspections  by  inspectors  employed by federal or state
regulatory  agencies.  In  addition,   federal  regulatory  authorities  require
participation  in a proficiency  testing program approved by the HHS for each of
the specialties and  subspecialties  for which a laboratory  seeks approval from
Medicare or Medicaid and licensure under CLIA '88.  Proficiency testing programs
involve actual testing of specimens that have been prepared by an entity running
an approved program for testing by the laboratory.


<PAGE>

         The Final Rule implementing CLIA '88,  published by HHS on February 28,
1992,  became  effective  September 1, 1992.  HHS currently has under review the
comments it received in response to the Final Rule, as well as those received in
response to revisions  to such rule  published on January 19, 1993 and April 24,
1995. This Final Rule covers all  laboratories  in the United States,  including
the Company's laboratory. The Company has reviewed the Final Rule (and revisions
thereto),  including,  among other things,  such rule's  requirements  regarding
laboratory  administration,  participation in proficiency testing,  patient test
management   (including  patient   preparation,   proper  specimen   collection,
identification,  preservation, transportation, processing and result reporting),
quality  control,  quality  assurance  and  personnel  for the types of  testing
undertaken  by the  Company,  and  believes  it to be in  compliance  with these
requirements.  However, no assurances can be given that the Company's laboratory
will pass all future inspections conducted to ensure compliance with CLIA '88 or
with any other applicable licensure or certification laws.

         Existing federal laws governing Medicare and Medicaid,  as well as some
state laws, also regulate certain aspects of the relationship between healthcare
providers,   including  clinical  laboratories,   and  their  referral  sources,
including physicians,  hospitals and other laboratories.  One provision of these
laws, known as the "anti-kickback  law," contains extremely broad proscriptions,
and  relatively  little  regulatory   guidance  or  judicial   precedent  exists
concerning its application.  Violation of this provision may result in exclusion
from Medicare and Medicaid or criminal  penalties.  Pronouncements  from the OIG
have indicated that additional enforcement resources may be focused on financial
arrangements  between  laboratories  and  physicians  and  other  purchasers  of
laboratory  services,  including  arrangements under which  laboratories  supply
physicians' offices with phlebotomists  (blood-drawing  technicians) who perform
additional  tasks that normally are the  responsibility  of the physician office
staff.  Under  another  provision,  known as the "Stark"  law or  "self-referral
prohibition",  physicians  who have an investment or  compensation  relationship
with an entity  furnishing  clinical  laboratory  services  (including  clinical
chemistry  and  anatomic  pathology   services)  may  not,  subject  to  certain
exceptions,  refer  clinical  laboratory  testing for Medicare  patients to that
entity.  Similarly,  laboratories may not bill Medicare or Medicaid or any other
party for services  furnished  pursuant to a prohibited  referral.  Violation of
these  provisions may result in disallowance of Medicare and Medicaid claims for
the affected  testing  services,  as well as the  imposition  of civil  monetary
penalties.  On August 14, 1995,  HHS  published a Final Rule  implementing  this
prohibition on Medicare referrals.  Both H.R. 2491 and the President's  Medicare
proposal contained modifications to the anti-kickback law and the Stark law. The
provisions  from H.R.  2491 have been  introduced  again in other bills in 1996.
While these  provisions in some respects ould strengthen the  anti-kickback  and
Stark  laws,  in  other  respects  they  would  moderate  some  of  the  current
restrictions.  The  Company  does not  expect  that these  changes,  if they are
enacted,  would  have a major  effect  on the  Company.  The  Company  seeks  to
structure  its  arrangements  with  physicians  and  other  providers  to  be in
compliance with the anti-kickback,  Stark and state laws, and to keep up-to-date
on  developments   concerning  their  application  by  various  means  including
consultation with legal counsel.  However,  the Company is unable to predict how
these laws will be applied in the future,  and no  assurances  can be given that
its arrangements will not become subject to scrutiny under them.

         Any  exclusion or  suspension  from  participation  in the Medicare and
Medicaid programs,  any loss of licensure or accreditation,  or any inability to
obtain any required  license or permit,  whether arising from any action by HHS,
any state,  or any other  regulatory  authority,  would have a material  adverse
effect on the Company's  business.  Any  significant  civil or criminal  penalty
resulting  from such  proceedings  could have a material  adverse  effect on the
Company's business.

         Food and Drug Administration

         The FDA regulates  certain  products  purchased by the Company but does
not  currently  regulate  laboratory  testing  services  which is the  Company's
principal  business.  However,  the Company performs some testing services using
test kits purchased from manufacturers for which final FDA pre-market  clearance
for  sale in the  United  States  has not  been  obtained  by the  manufacturers

<PAGE>

("investigational test kits"). Under current FDA regulations and policies,  such
investigational  test kits may be sold by manufacturers for  investigational use
if certain requirements are met. The manufacturers of these investigational test
kits are responsible for marketing them under conditions  meeting applicable FDA
requirements.  If the Company were to be  substantially  limited in or prevented
from  purchasing  investigational  test kits by  reason of the FDA  taking a new
regulatory  direction  in this  area,  there  could be  adverse  effects  on the
Company's ability to access new technology,  which could have a material adverse
effect on the Company's business.

         The FDA is currently  considering  new  guidelines  with respect to the
sale of unapproved  in vitro  diagnostic  test kits and other  products that are
sold under "investigational use only" or "research use only" labeling.  While it
is  uncertain  what the  final  substance  of these  guidelines  will be,  these
guidelines could place restrictions on the distribution and use of products used
by the Company to provide testing services.  In addition, on March 14, 1996, the
FDA published a proposed rule regarding the classification and  reclassification
of  analyte  specific  reagents  ("ASRs").  This  proposal,  if  promulgated  as
published,  could also place restrictions on the sale,  distribution,  labeling,
and use of  products  used by the  Company  to  provide  testing  services.  The
ultimate  scope of the proposed  rule and how various ASRs will be classified is
still unclear,  and thus the impact on the Company's  testing services cannot be
determined at this time.

         Other

         Certain  federal and state laws  govern the  handling  and  disposal of
medical  specimens,  infectious and hazardous wastes and radioactive  materials.
Failure to comply with such laws could  subject an entity  covered by these laws
to fines, criminal penalties and/or other enforcement actions.

         Pursuant to the Occupational Safety and Health Act, laboratories have a
general  duty to  provide  a work  place to their  employees  that is safe  from
hazard.   Over  the  past  few  years,  the   Occupational   Safety  and  Health
Administration  ("OSHA") has issued rules  relevant to certain  hazards that are
found in the  laboratory.  In  addition,  OSHA  recently has  promulgated  final
regulations containing  requirements healthcare providers must follow to protect
workers from  bloodborne  pathogens.  Failure to comply with these  regulations,
other  applicable  OSHA  rules or with the  general  duty to provide a safe work
place could subject an employer, including a laboratory employer, to substantial
fines and penalties.

Recent Developments

         On February 27, 1997,  the Company  announced that Kevin C. Johnson has
been named as the Chief  Executive  Officer of the Company in addition to duties
as President of the Company.  In connection  with this  transition,  the Company
also  announced  that  Richard A.  Sandberg,  a co-founder  of the Company,  has
resigned as Chairman of the Company's  Board of Directors  while  remaining as a
director and  consultant  to the Company and that John P. Davis was appointed as
non-executive Chairman of the Company's Board of Directors,  for which Mr. Davis
previously acted as Vice Chairman.  In addition,  G.S. Beckwith Gilbert has been
elected as Chairman of the Executive Committee.

ITEM 2.  PROPERTIES

         The  Company  leases  approximately  90,850  square  feet of office and
laboratory  space in Stratford,  Connecticut and  Wilmington,  Ohio under leases
which will expire in December 1997 and May 2003 for the  Stratford,  Connecticut
facilities and March 2001 for the  Wilmington,  Ohio facility,  each  containing
renewal options (See Note 4 to the Company's  consolidated  financial statements
included  herewith).  The Company leases five regional sales offices  located in
Florida, Maryland, North Carolina, Texas and Ohio. The terms of the leases range
from one to three years.


<PAGE>

ITEM 3.  LEGAL PROCEEDINGS

         None.

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         On October  24,  1996,  the  Company  held its 1996  Annual  Meeting of
Shareholders  at which the  following  actions  were  approved:  directors  were
elected;  the Company's  agreement with G.S. Beckwith Gilbert and certain of his
affiliates  that Mr. Gilbert and such  affiliates be permitted to vote shares of
the  Company's  Common Stock  purchased by them from the Company in October 1995
representing  up to  20% of the  total  voting  power  of the  Company's  voting
securities  outstanding  from time to time  (the"Voting  Rights  Proposal")  was
approved;  the adoption of the Company's 1996 Stock Incentive Plan was approved;
and the appointment of Arthur Andersen, LLP ("Arthur Andersen") as the Company's
independent public accountants for the calendar year ended December 31, 1996 was
ratified.  At the 1996  Annual  Meeting  of  Shareholders,  Messrs.  Richard  A.
Sandberg,  Kevin C. Johnson,  John P. Davis,  Walter O.  Fredericks,  Jeffrey L.
Sklar, G.S. Beckwith Gilbert and Dr. James B. Amberson were elected as directors
of the Company. The vote for Messrs. Sandberg,  Johnson, Davis, Fredericks,  and
Gilbert and Dr.  Amberson's  election each consisted of 5,342,400  votes for and
42,479 votes against and the vote for Dr. Sklar consisted of 5,339,982 votes for
and 44,897 votes against.

The other  actions taken at the Company's  1996 Annual  Meeting of  Shareholders
were approved pursuant to the following votes:

<TABLE>
<CAPTION>
                                                                                     Broker
                                                For        Against    Absentions   Non-Votes
                                                ---        -------    ----------   ---------

<S>                                          <C>           <C>          <C>        <C>      
1.  Approve the Voting Rights Proposal       2,802,331     188,597      17,951     2,333,521

2.  Adopt 1996 Stock Incentive Plan          2,403,912     555,980      49,158     2,333,521

3.  Ratify appointment of Arthur Andersen
    as the  Company's  independent  public
    accountant for the calendar year ended
    December 31, 1996                        5,622,438       6,403       3,408       289,849

</TABLE>



<PAGE>

                                    PART II



ITEM 5.  MARKET  FOR THE  REGISTRANT'S  COMMON EQUITY AND RELATED  STOCKHOLDER
         MATTERS

         DIANON's  Common  Stock  trades on The Nasdaq  Stock  Market  under the
symbol  "DIAN".  The following  table shows the high and low sales prices of the
Company's  Common  Stock  quoted on the Nasdaq  Stock  Market,  for the  periods
indicated below:

<TABLE>
<CAPTION>
                                   High              Low
                                   ----              ---
         <S>                       <C>               <C>
         1995:
         First Quarter             6-1/8             3-3/4
         Second Quarter            5-1/4             4-3/8
         Third Quarter             5-3/4             4-7/16
         Fourth Quarter            5                 3-1/4

         1996:
         First Quarter             5-1/2             3-3/8
         Second Quarter            8-5/8             4-1/8
         Third Quarter             7-3/8             4-1/2
         Fourth Quarter            9-5/16            6-3/8
</TABLE>

         As of March 14, 1997, the Company had approximately  2,511 shareholders
of record.  No dividends have been paid by DIANON and it is not anticipated that
any will be paid in the foreseeable future.


<PAGE>

ITEM 6.  SELECTED FINANCIAL DATA

<TABLE>
<CAPTION>
Statement of Operations:                1996       1995      1994        1993        1992
                                        ----       ----      ----        ----        ----
                                               (in thousands, except per share data)

    <S>                              <C>        <C>        <C>         <C>         <C>     
    Net revenues(1)                  $ 56,000   $ 45,700   $ 41,017    $ 38,250    $ 34,456

    Gross profit(1)                    29,101     25,310     24,300      24,311      21,832

    Expenses:
     Selling(1)                        10,618      9,709      9,008       9,783       7,885
     Marketing                          3,160      1,811      1,856       1,911       1,807
     Research and development           3,157      5,255      4,512       4,342       3,369
     General and administrative(1)      8,666      8,100      6,641       7,123       7,204
                                     --------   --------   --------    --------    --------
          Total expenses(2)            25,601     24,875     22,017      23,159      20,265

    Income from operations              3,500        435      2,283       1,152       1,567

    Net interest income (expense)         307        181        (90)        (36)        223
    Provision for income taxes(3)       1,637        509        832         270         776
                                     --------   --------   --------    --------    --------
    Net income                       $  2,170   $    107   $  1,361    $    846    $  1,014
                                     --------   --------   --------    --------    --------
    Net income per share             $    .34   $    .02   $    .26    $    .16    $    .19
    Weighted average shares
      outstanding                       6,331      5,563      5,310       5,337       5,451
    Dividend per share                   None       None       None        None        None

Balance Sheet Data:

    Working capital                  $ 18,058   $ 16,974   $ 11,931    $ 11,110   $  11,518
    Total assets                       34,536     30,455     25,206      24,614      21,103
    Long-term obligations                 272        750      1,674       2,519         194
    Stockholders' equity               26,549     23,452     18,664      17,147      16,373

<FN>
- ----------
(1)  Since implementing the restructuring of the international operations at the
     end of the third quarter of 1992, international operating results have been
     consolidated with domestic operating results in the consolidated statements
     of operations.  Applying the same  accounting  principles to prior periods,
     the  Company's  revenue,   cost  of  goods  sold,   selling,   general  and
     administrative  expenses  for  1992  were  higher  by  $327,000,  $217,000,
     $1,028,000, respectively.

(2)  During 1996, 1995, 1994, 1993 and 1992,  non-recurring  charges relating to
     severance, restructuring, accelerated amortization and other one-time costs
     of $609,000, $2,668,000, $692,000, $2,542,000 and $1,674,000, respectively,
     were  incurred.  (See Notes 2, 7, 10 and 13 to the  Company's  consolidated
     financial statements included herewith).

(3)  The Company's  provision for income taxes in 1995,  1994, and 1993 includes
     the benefit  received from the  utilization of tax credits.  (See Note 3 to
     the Company's consolidated financial statements included herewith).
</FN>
</TABLE>


<PAGE>

ITEM 7.   MANAGEMENT'S  DISCUSSION  AND  ANALYSIS  OF RESULTS OF OPERATIONS AND
          FINANCIAL CONDITION.

Results of Operations

o        Net Revenues

         Net revenues  were $56 million in 1996, an increase of $10.3 million or
23% from 1995. Increased sales were attributable to increased market penetration
by the Company's anatomic  pathology testing services.  The increase in anatomic
pathology  services in 1996 over 1995 was offset to some extent by a decrease in
clinical chemistry and hospital based tissue testing services.

         Net revenues were $45.7 million in 1995, an increase of $4.7 million or
11% from 1994. Increased sales were attributable to increased market penetration
by the Company's anatomic  pathology testing services.  The increase in sales in
1995 and 1994 was offset to some extent by a decrease in clinical  chemistry and
hospital based tissue testing services.

o        Cost of Sales

         Cost  of  sales,  which  consists  primarily  of  payroll,   laboratory
supplies,  outside services,  logistics  (primarily shipping and handling),  and
depreciation  expense,  was $27 million during 1996, an increase of $6.5 million
or 32% from 1995. Salaries and wages were approximately $8.7 million in 1996, an
increase of $2.6 million or 43% from 1995.  This increase was principally due to
the average number of full time equivalent  laboratory employees rising from 143
in 1995 to 193 in 1996. This increase in laboratory headcount was due in part to
the  growth  of the  Company's  anatomic  pathology  testing  services  in 1996.
Laboratory  supplies  were  approximately  $5.7 million in 1996,  an increase of
$865,000 or 18% from 1995.  This  increase  was the result of higher  volume and
costs for reagents used for some of the Company's  testing  services.  Logistics
were $4.6 million in 1996,  an increase of $638,000 or 16% from 1995,  primarily
due  to  higher  sales  volume.  Overhead  expenses  (primarily  building  rent,
utilities and  depreciation)  were $7.9 million  during 1996 an increase of $2.1
million or 36% over 1995.  This  increase was due  primarily  to the  additional
facilities  oriented expenses  associated with the introduction of the Company's
new anatomic pathology testing service product line, specifically in the form of
additional  depreciation  and  building  expenses  incurred  from the  continued
expansion  and  equipping of the  Company's  facilities.  As a percentage of net
revenues, cost of sales increased to 48% during 1996 from 45% during 1995.

         Cost of sales  was $20.4  million  during  1995,  an  increase  of $3.7
million or 22% from 1994.  Salaries and wages were approximately $6.1 million in
1995,  an  increase  of  $1.7  million  or 39%  from  1994.  This  increase  was
principally  due to the  average  number  of  full  time  equivalent  laboratory
employees  increasing  from  112 in  1994  to  143 in  1995.  This  increase  in
laboratory  headcount  was  incurred in part to support new  anatomic  pathology
testing  services  and in  part to  prepare  for  anticipated  growth  in  1996.
Laboratory  supplies  were  approximately  $4.8 million in 1995,  an increase of
$544,000 or 13% from 1994.  This  increase  was the result of rising  volume and
increased  costs for reagents used for some of the Company's  testing  services.
Logistics were $4 million in 1995, an increase of $280,000 or 8% from 1994. This
increase  was  due to  increased  sales  volume.  Overhead  expenses  (primarily
building  rent,  utilities and  depreciation)  were $5.5 million during 1995, an
increase of $1.1 million or 26% over 1994.  This  increase was due  primarily to
the additional  facilities oriented expenses associated with the introduction of
the Company's new anatomic  pathology product line,  specifically in the form of
additional   depreciation  and  building  expenses  incurred  from  the  initial
expansion  and  equipping of the  Company's  facilities.  As a percentage of net
revenues, cost of sales increased to 45% during 1995 from 41% during 1994.

o        Gross Profit

         As a result  of the  increase  in sales  volume in 1996,  gross  profit
increased $3.8 million from 1995. The Company's gross profit margin decreased to
52% in 1996 from 55% in 1995. The gross profit margin continued to decrease from
1995 to 1996 due to the  erosion of the  average  price  reimbursed  for certain
clinical  chemistry  testing  services  and the  higher  costs  associated  with
providing anatomic pathology testing services.

         Gross profit was $25.3  million in 1995, an increase of $1.0 million or
4% from 1994. As a percentage of net revenues,  gross profit decreased to 55% in
1995 from 59% in 1994.  The gross profit margin  continued to decrease from 1994
to 1995 due to the erosion of the average price  reimbursed for certain clinical
chemistry  testing  services  and the higher  costs  associated  with  providing
anatomic pathology testing services.


<PAGE>

         The  clinical  laboratory   industry,   which  includes  both  clinical
chemistry and anatomic  pathology,  has seen steady downward  pressure on prices
exerted by both  government  and private third party payors.  Also,  payment for
services such as those provided by the Company is and likely will continue to be
affected by periodic  reevaluations  made by payors concerning which services to
reimburse and which to cease reimbursing.  The reduction in reimbursement rates,
particularly  by Medicare,  has  generally  decreased the average unit price for
most of the  Company's  clinical  chemistry  services each year. In keeping with
this trend, as part of OBRA '93,  Congress reduced over time the national cap on
Medicare laboratory fee schedules.  This national cap has been lowered each year
and now is 76% of the  national  median.  OBRA '93 also  eliminated  the  annual
updates of Medicare  laboratory  fee  schedules  for the years 1994 and 1995. In
1996, however, the fee schedule update was 3.2%; the HCFA has recently announced
that the fee schedule update for 1997 will be 2.7%.  However,  the corresponding
expected  national  cap  increase  of 2.7%  may not be fully  realized  due to a
recalculation  of national  medians  necessitated  by conversion in some carrier
areas to a single statewide fee schedule.

         With respect to the Company's  tissue  testing  services  which are not
reimbursed  under the Medicare  laboratory fee schedules,  the Medicare fees for
these  services also  generally  declined with the  implementation  of the RBRVS
system  which  went into  effect  in 1992 and was fully  phased in by the end of
1996.  The Medicare  RBRVS payment for each service is calculated by multiplying
the total RVU's  established for the service by a conversion  factor that is set
by law. The number of RVU's  assigned to each service is in turn  calculated  by
adding three separate  components,  including one representing the relative work
values.  In 1996, HCFA completed a five-year  review of the work value component
and, as a result,  revised  the work value  amount  assigned  to many  physician
services.  In addition,  based on a default formula established in law, the 1997
conversion  factor for nonsurgical  services  dropped 0.8% from 1996 to $33.8454
per conversion factor. The changes resulting from the five-year review, combined
with the  conversion  factor  reductions,  resulted  in an overall  decrease  in
payments for pathology services of approximately 5.7% beginning January 1, 1997.
Also, HCFA reduced the number of physician fee schedule payment  localities from
210 to 89,  effective  January 1, 1997.  Connecticut  was one of the states that
HCFA  moved to a single  payment  locality.  This  modification  created  a 3.2%
decrease in the RBRVS  geographic  adjustment  factor for physicians  located in
Eastern Connecticut,  where the Company's primary operations are located. In the
past, implementation of the RBRVS program has had the effect of reducing prices,
and  thus the  gross  profit,  of the  Company.  The  recent  substantial  RBRVS
adjustments are likely to continue this trend.

         Furthermore, as a result of the Social Security Act amendments of 1994,
Medicare is required to revise the formula for calculating the practice  expense
component of the physicians'  Medicare fee schedule from the current  historical
basis to a resource  basis  beginning  January 1, 1998.  Some  concern  has been
expressed  by  physician  specialty  groups that this data HCFA plans to use for
these revisions is not adequate and that the agency's  methodology  could result
in specialty  practice  expenses being  underestimated.  At this point,  HCFA is
considering a variety of options for calculating practice expense revisions.  It
is  possible  that  certain  changes  HCFA might  make would have a  significant
negative affect on reimbursement,  and thus gross profit, for anatomic pathology
services.  Practice  expenses  currently  account for  approximately  42% of the
physicians' Medicare fee schedule payment amount.

         Any  future   changes  in  government  and  other   third-party   payor
reimbursement  which may come about as a  consequence  of an enactment of health
care reform or of deficit  reduction  legislation  also likely will continue the
downward pressure on prices and make the market for clinical laboratory services
more  competitive.  Changes in  government  reimbursed  medicare,  as previously
described in the  reimbursement  section are possible this year.  Because of the
uncertainties  about the exact  nature of any changes  which may  ultimately  be
adopted,  however,  the Company  currently is unable to predict  their  ultimate
impact on the  clinical  laboratory  industry  generally  or on the  Company  in
particular. Even apart from federal legislative action, reforms may occur at the
state level and changes are occurring in the  marketplace  as a result of market
pressures,  including the increasing  number of patients covered by some form of
managed care. In the past,  the Company has offset a substantial  portion of the
impact of price  decreases  and  coverage  changes  through the  achievement  of
economies  of  scale  and  other  strategies  such  as more  favorable  purchase
contracts and the introduction of alternative  technologies.  However,  if price
decreases  (for example  arising from the proposed  Medicare  changes  discussed
above) or coverage changes were to be rapidly and fully implemented,  they would
be likely to have an adverse impact on gross profits from the Company's  testing
services  until  management  was able to mitigate such impact.  Furthermore,  in
recent years the Company's gross profit margin has trended down from over 60% to
about 52%, and there can be no assurances that such trends may not continue.


<PAGE>

o        Selling, General and Administrative Expenses

         Selling,  general and  administrative  expenses were $22 million during
1996, an increase of $4.9 million or 29% from 1995.  General and  administrative
expenses  were $11.6  million in 1996,  an increase of $3.0  million or 35% from
1995. These increases were primarily attributed to higher sales levels resulting
in increased selling, general and administrative activities of the Company. As a
percentage  of  net  revenues,  selling,  general  and  administrative  expenses
increased to 39% in 1996 from 37% in 1995.

         Selling,  general and administrative expenses were $17.1 million during
1995,  an  increase of  $249,000  or 1% from 1994.  General  and  administrative
expenses  were $8.6  million in 1995,  an  increase of $234,000 or 3% from 1994.
These  increases were primarily  attributed to higher sales levels  resulting in
increased selling,  general and administrative  activities of the Company.  As a
percentage  of  net  revenues,  selling,  general  and  administrative  expenses
decreased to 37% in 1995 from 41% in 1994.

o        Research and Development

         Research  and  development  expenses  include the costs of building the
Company's database and the review,  analysis and clinical evaluation of existing
as well as new technologies. Research and development expenses were $3.1 million
in 1996,  a decrease  of  approximately  $2.1  million  or 40% from  1995.  This
decrease in 1996 is primarily due to the completion in 1996 of the major portion
of expenditures for the development of the new anatomic pathology services. As a
percentage of net revenues,  research and development  expenses  decreased to 6%
during 1996 compared to 12% in 1995.  With the  completion  of such  development
activities,  it is  expected  that such  expenditures  will  represent a smaller
percentage of sales in future years.

         Research  and  development  expenses  were  $5.3  million  in 1995,  an
increase of approximately $743,000 or 16% from 1994.

o        Amortization Expense

         Amortization   expenses   were   $399,000   in  1996,   a  decrease  of
approximately  $866,000  or 68% from 1995.  In the fourth  quarter of 1996,  the
Company   recorded  an   extraordinary   accelerated   amortization   charge  of
approximately   $44,000  based  on  management's  estimate  of  future  benefits
anticipated   from  a  customer  list   (compared  to  a  $765,000   accelerated
amortization charge in 1995).

         Amortization  expenses  were  $1.3  million  in 1995,  an  increase  of
approximately  $723,000 or 133% from 1994.  In the second  quarter of 1995,  the
Company   recorded  an   extraordinary   accelerated   amortization   charge  of
approximately  $765,000  based  on  management's  estimate  of  future  benefits
anticipated from a customer list (no such charge was recorded in 1994).

         Amortization  expense,   severance  costs,  investment  write-down  and
restructuring  costs  have been  included  in  general  and  administrative  and
research and development  expenses in the consolidated  statements of operations
in the Company's consolidated financial statements included herewith.

o        Severance Costs

         During 1996, the Company recorded a reserve of  approximately  $148,000
for severance  costs as a result of the  resignation of certain  officers of the
Company.  Severance  costs  are  expected  to be paid  by the end of the  second
quarter of 1997.

         During 1995, the Company recorded a reserve of  approximately  $595,000
for severance costs as a result of the streamlining  its operating  expenses and
the resignation of certain officers of the Company. Severance costs were paid by
the end of the second quarter of 1996.


<PAGE>

         Amortization  expense,   severance  costs,  investment  write-down  and
restructuring  costs  have been  included  in  general  and  administrative  and
research and development  expenses in the consolidated  statements of operations
in the Company's consolidated financial statements included herewith.

o        Investment Write-down

         During  1996 and 1995,  the  Company  recorded  charges of $62,000  and
$530,000,  respectively,  to write  down the  investment  in  common  stock of a
publicly  traded  company to market  value as the loss in value was deemed other
than  temporary in accordance  with Statement of Financial  Accounting  Standard
115,  "Accounting for Certain  Investments in Debt and Equity  Securities".  The
Company  plans to sell its  remaining  24,386  shares  of  common  stock of such
company in 1997.

         Amortization  expense,   severance  costs,  investment  write-down  and
restructuring  costs  have been  included  in  general  and  administrative  and
research and development  expenses in the consolidated  statements of operations
in the Company's consolidated financial statements included herewith.

o        Restructuring Costs

         In 1995, the Company provided a reserve of $279,000 due to management's
decision to discontinue  European based operations.  Remaining  reserves for the
discontinuance  of such  operations  at  December  31,  1996  are  approximately
$155,000.  The  Company is in the  process of  liquidating  the  European  based
operations and plans to complete the liquidation  process by the end of the 1997
fiscal year.

         Amortization  expense,   severance  costs,  investment  write-down  and
restructuring  costs  have been  included  in  general  and  administrative  and
research and development  expenses in the consolidated  statements of operations
in the Company's consolidated financial statements included herewith.

o        Interest Income

         Cash and cash  equivalents  as of December  31, 1996 was  approximately
$7.5  million of which  approximately  $6 million was  invested at year end. The
Company's  interest income was  approximately  $384,000 for 1996, an increase of
approximately $67,000 or 21% from 1995.

         Cash and cash equivalents as of December 31, 1995 was approximately $11
million.  Approximately  $4.6 million  came from a private  placement in October
1995.  The  Company's  interest  income was  approximately  $317,000 for 1995, a
increase  of  approximately  $214,000 or 207% from 1994 which was caused both by
higher  interest  rates and by  investing  over $4.6  million  from the  private
placement completed in October 1995.

o        Interest Expense

         Interest  expense was  approximately  $77,000  for 1996,  a decrease of
$59,000 or 43% from 1995.  The decrease in interest  expense during 1996 was due
to the pay-down of a portion of the $3.5 million term loan obtained in July 1993
which bears interest at 6% per year.

         Interest  expense was  approximately  $136,000  for 1995, a decrease of
$58,000 or 30% from 1994.  The decrease in interest  expense during 1995 was due
to the  pay-down  of a portion of the $3.5  million  term loan  obtained in July
1993.


<PAGE>

o        Provision for Income Taxes

         Provision for income tax expense was approximately $1,637,000 for 1996,
representing  an increase of  approximately  $1.1 million or 222% from 1995 as a
result  primarily of higher pretax income (pretax income  increased  518%).  The
effective tax rate was 43% during 1996 compared to 83% for 1995.

         Provision for income tax expense was  approximately  $509,000 for 1995,
representing a decrease of approximately $323,000 from 1994 as a result of lower
pretax  income.  The  effective tax rate was 83% during 1995 compared to 38% for
1994.  The  increase  in the  effective  tax rate during 1995 was due to certain
expenses not being deductible for tax purposes  including  $530,000 arising from
the write-down of the investment in common stock of a publicly traded company.

o        Net Income

         As a result of the  foregoing,  1996 net  income  was $2.2  million  as
compared to $107,000 in 1995. Net income for 1995 decreased  approximately  $1.3
million  or 92% from  1994.  Net income  for 1995  includes  approximately  $2.2
million in pretax extraordinary charges relating to severance, restructuring and
other extraordinary costs as compared to $254,000 for similar charges in 1996.

o        Earnings Per Share

         Earnings per share were $.34 in 1996, as compared to $.02 in 1995.  The
extraordinary charges incurred in 1995 (described in the immediately  succeeding
paragraph) represented approximately a $.23 reduction in 1995 earnings per share
(using an approximate pro forma 41% effective tax rate).  Extraordinary  charges
were substantially less in 1996, representing  approximately a $.02 reduction in
1996 earnings per share (using an approximate pro forma 41% effective tax rate).

         Earnings per share were $.02 in 1995, as compared to $.26 in 1994.  The
non-recurring  charges  for the  accelerated  amortization  of a  customer  list
recorded  in the  second  quarter  of  1995  for  $765,000,  the  write-down  of
investment for $530,000,  the international  restructuring  reserve for $279,000
and the severance costs for $595,000 represented  approximately a $.23 reduction
in 1995 earnings per share using a pro forma effective tax rate of approximately
41%.

o        Liquidity and Capital Resources

         As  of  December  31,  1996,  the  Company  had  total  cash  and  cash
equivalents  of $7.5 million which was invested in a fund holding U.S.  Treasury
securities with maturities of less than three months.

         As of December  31,  1996,  the  Company  had working  capital of $18.1
million  compared to $17.0  million at December  31, 1995.  The working  capital
ratio as of December  31, 1996 was 3.4 to 1 compared to 3.7 to 1 at December 31,
1995.

         Domestic trade receivables,  net, were $15.2 million as of December 31,
1996,  an increase of $5.7 million or 61% from  December  31,  1995.  During the
fourth  quarter of 1996,  the  average  number of days sales in  domestic  trade
receivables was  approximately 79 days as compared to 65 days for the comparable
period of 1995.  The  increase  in average  number of days sales was a result of
increased volume in the growth of the Company's  anatomic pathology services and
increased complexity of billing for anatomic pathology services.

         Capital  expenditures  for 1996, 1995 and 1994 were $3.4 million,  $2.3
million  and $1.6  million,  respectively.  Capital  expenditures  for 1996 were
mainly for the expansion of the Company's laboratory  facilities.  Approximately
$1.9 million related to leasehold  improvements to expand the Company's physical
plant in  Stratford,  CT and to develop the  Company's  new specimen  processing
facility in Wilmington, OH.

         In July 1993, the Company obtained a $3.5 million term loan from a bank
bearing interest at 6% per year and payable over a 47 month period. During 1995,

<PAGE>

the loan agreement was modified to revise certain financial covenants, including
those with respect to tangible net worth and debt service coverage  requirements
and limitation on certain  expenditures.  The principal  outstanding  under such
term loan is approximately  $650,000 as of December 31, 1996 (See Note 11 to the
Company's consolidated financial statements included herewith).

         On  October  5,  1995,  the  Company  completed  a  $5,612,000  private
placement with an investor for one million shares of Common Stock and a two-year
warrant  for  800,000  shares  exercisable  at $6.00 per  share of Common  Stock
(except as otherwise  described below).  The Company received cash of $5,316,000
and a two-year promissory note for $296,000 bearing 7% interest.  Some or all of
the  warrants  could be  exercised  at a price of $5.00 at any time on or before
October 31, 1996. Upon such election the Company would be required to extinguish
as an adjustment  to the purchase  price paid for such  warrants,  for each such
warrant for which such election has been made,  $0.37 of the principal amount of
the note upon payment of the interest  due on such  extinguished  amount for the
outstanding  period. If the warrants for 800,000 shares were all exercised on or
before  October 31, 1996,  the two year  promissory  note for $296,000  would be
fully  extinguished.  On August  20,  1996,  the  Company's  Board of  Directors
approved an  amendment  to the terms of the  warrants to extend from  October 4,
1996 to October 31, 1996, the date through which the warrants could be exercised
at $5.00 per share. The amendment was approved in connection with the scheduling
of the  Company's  Annual  Meeting for October 24, 1996 to enable voting at such
meeting on the Company's  agreement to enable the investor to vote shares of the
Company's   common  stock  owned  by  such   investor  and  certain   affiliates
representing  up to  20% of the  total  voting  power  of the  Company's  voting
securities outstanding from time to time to be completed prior to the expiration
of the $5.00 per share exercise price.  The Company's  agreement was approved at
the  Company's  Annual  Meeting on October 24, 1996.  On October 29,  1996,  the
investor  exercised  warrants  for all 800,000  shares and in  exchange  for the
payment  of  approximately  $4.0  million  in cash  representing  the  aggregate
exercise  price of such  warrants  and interest on the  principal  amount of the
two-year  promissory note for the outstandng  period,  the Company issued to the
investor 800,000 shares of its Common Stock and fully extinguished and cancelled
the promissory note.

         As of December 31, 1996,  the Company had purchased  117,196  shares of
Common Stock as required by its  Employee  Stock  Purchase  Plan  ("ESPP").  The
Company's  Board of Directors has authorized  additional  acquisitions  for ESPP
requirements for further additional share repurchases costing up to $2,000,000.

         The Company believes that cash flows from operations and available cash
and cash  equivalents  are  adequate to fund the  Company's  operations  for the
foreseeable future.

Risk Factors; Forward Looking Statements

         The Management's  Discussion and Analysis and the information  provided
elsewhere in this 10K (including,  without  limitation,  in the third and fourth
paragraphs of "Item 1.  Business" and under "Gross  Profit" and  "Liquidity  and
Capital  Resources"  above) contain  forward  looking  statements  regarding the
Company's future plans, objectives,  and expected performance.  These statements
are based on  assumptions  that the Company  believes  are  reasonable,  but are
subject  to a wide  range of risks and  uncertainties,  and a number of  factors
could  cause the  Company's  actual  results  to differ  materially  from  those
expressed in the  forward-looking  statements  referred to above.  These factors
include,   among  others,   the   uncertainties  in   reimbursement   rates  and
reimbursement  coverage of various tests sold by the Company to beneficiaries of
the  Medicare  program  (see e.g.  Item 1 - Business -  "Reimbursement");  being
deemed to be not in  compliance  with Federal or state  regulatory  requirements
(see e.g. Item 1 - Business - "Regulatory");  the uncertainties  relating to the
ability of the Company to convince  physicians and/or managed care organizations
to use the Company as a provider of anatomic  pathology  testing  services;  the
ability of the Company to maintain superior quality relative to its competitors;
the ability of the Company to maintain its  hospital-based  business in light of
the competitive pressures and changes occurring in hospital healthcare delivery;
the  uncertainties  relating to states  erecting  barriers to the performance of
anatomic  pathology  testing by  out-of-state  laboratories;  the ability of the
Company  to  find,  attract  and  retain  qualified   management  and  technical
personnel;  the  uncertainties  associated with  competitive  pressures from the
large national laboratories, small specialized laboratories and well established
local  pathologists;  and the  uncertainties  which  would  arise if  integrated
delivery  systems  closed to outside  providers  emerged as the dominant form of
health care delivery.



<PAGE>

                                    PART III


ITEM 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

         The Company's  consolidated  financial  statements and schedule and the
reports of independent public accountants  thereon appear beginning on page F-2.
See index to such consolidated financial statements and schedules and reports on
page F-1.

ITEM 9.  DISAGREEMENTS ON ACCOUNTING AND FINANCIAL DISCLOSURE

         None

ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

         The following  information with respect to the principal  occupation or
employment,  other  affiliations  and business  experience  of each director and
executive  officer  during the last five years has been furnished to the Company
by  such  director  or  executive  officer.  Except  as  indicated,  each of the
directors and executive  officers has had the same principal  occupation for the
last five years.

Information Regarding Directors

         Set forth  below is certain  information  concerning  each  director of
Dianon Systems, Inc.

         Richard A. Sandberg, age 54, is a founder of the Company, and served as
either Chief Executive  Officer or Co-Chief  Executive Officer and as a director
from the  Company's  inception  until  May 1996.  Mr.  Sandberg  also  served as
Chairman  of the Board  from 1989 to  February  1997.  He  currently  serves the
Company as a Director and consultant.  Mr. Sandberg also serves as a Director of
UroMed Corporation.

         Kevin C.  Johnson,  age 42, a  Director  since May 1996,  has served as
President since May 1996,  when he joined the Company.  In February 1997, he was
given the additional title of Chief Executive Officer. Formerly, Mr. Johnson was
with Corning  Inc., a  manufacturer  of  specialty  materials  and a provider of
laboratory services, for eighteen years, serving most recently as Vice President
and  General  Manager  of  Corning  Clinical  Laboratories'  largest  region  in
Teterboro, New Jersey.

         John P. Davis,  age 55, a Director  since 1984,  is President and Chief
Executive Officer of Calypte  Biomedical  Corp., a diagnostic  products company.
From 1984 to January  1995,  Mr. Davis was an officer of the Company.  Mr. Davis
joined the Company in January 1984 as President and Chief Operating Officer, and
subsequently  became  co-Chief  Executive  Officer  in 1992 and Chief  Executive
Officer in 1994. In January 1995, Mr. Davis resigned as Chief Executive  Officer
of the Company and became Vice Chairman of the Board.  As of February  1997, Mr.
Davis was elected non-executive  Chairman of the Board. Mr. Davis also serves as
a Director of PepGen Corporation.

         Walter O.  Fredericks,  age 57, a Director  since  1989,  is  Chairman,
President and Chief Executive  Officer of Lifecodes  Corporation and Chairman of
Cellmark Diagnostics,  Inc., both of which are in the human identity testing and
product  supply  field.  Mr.  Fredericks  is  also  President  and  Chairman  of
Electronic Instruments International  Corporation,  a manufacturer of electronic
instrumentation.

         Jeffrey L. Sklar, age 49, a Director since 1994, is director,  Division
of Diagnostic  Molecular Biology,  Department of Pathology,  Brigham and Women's
Hospital. Dr. Sklar is Professor of Pathology, Harvard Medical School, and since
1992, Dr. Sklar has also served as Director,  Molecular  Diagnostic  Laboratory,
Dana-Farber Cancer Institute. Dr. Sklar presently serves on the Editorial Boards
of the American  Journal of Pathology  and Genes,  Chromosomes,  and Cancer.  In
addition,  Dr. Sklar serves on the  Scientific  Advisory  Committee for Clinical
Science, The Fred Hutchinson Cancer Center, Seattle,  Washington; the Scientific
Advisory Committee, New England Primate Research Center, Harvard University; and
the Pathology B Study Section, National Institutes of Health. Dr. Sklar holds an
M.D.  and  Ph.D.  from  Yale  University  and a  M.A.  (honorary)  from  Harvard
University.


<PAGE>

         G. S.  Beckwith  Gilbert,  age 55, a Director  since  October  1995, is
President,  Chief  Executive  Officer  and a  Director  of Field  Point  Capital
Management  Company in Greenwich,  Connecticut,  a merchant  banking  firm.  Mr.
Gilbert is also a partner of Wolsey & Co., a merchant  banking firm. Mr. Gilbert
serves as a Director of Davidson Hubeny Brands, Inc. and TMS Technologics,  Inc.
Mr.  Gilbert is a graduate of Princeton  University  and has an M.B.A.  from New
York  University.  In February  1997,  Mr.  Gilbert was elected  Chairman of the
Executive Committee.

         James B.  Amberson,  age 45, a Director  since  January 1995, is Senior
Vice President, Operations and Chief Medical Officer. Dr. Amberson joined DIANON
in 1989 as Director,  Cytometry  Business Unit, and has served as Vice President
of  Pathology  Services,  Vice  President  of Medical  Affairs  and Senior  Vice
President and General Manager of the Anatomic  Pathology Unit before his present
position. Prior to joining the Company, he was Assistant Professor of Pathology,
Cornell  University  Medical  College for six years.  Dr. Amberson holds an M.D.
from Johns Hopkins University,  and an M.B.A. from Columbia University School of
Business.

Compensation of Directors

         Directors who are not employees of the Company are paid $1,500 for each
meeting of the Board of  Directors  attended in person and $500 for each meeting
attended by  telephone.  In addition,  committee  members are paid $500 for each
committee  meeting  attended  which  does  not  occur on the same day as a Board
meeting.  Directors are also  reimbursed for expenses to attend  meetings of the
Board and its committees.  In addition, the Company has made payments to Brigham
& Women's Hospital, Inc. for which Dr. Sklar is director, Division of Diagnostic
Molecular  Biology,  Department  of  Pathology.  (See  Note 6 to  the  Company's
consolidated financial statements included herewith.)

         Pursuant to the Company's 1996 Stock Incentive Plan,  Directors who are
not employees of the Company receive (i) automatic  initial and quarterly grants
of stock options with tandem limited stock  appreciation  rights  beginning July
1995,  (ii)  automatic  quarterly  grants of shares  of Common  Stock  beginning
January 1997 and (iii)  additional  stock  options or other equity awards to the
extent granted by the Board of Directors in its discretion.

         Each initial and quarterly stock option which is automatically  granted
under such plan is  exercisable  for that number of shares  obtained by dividing
$5,000  by the  closing  price of the  Common  Stock on the date of grant and is
exercisable  at that price.  Each such option has a 10-year  term and vests with
respect to 10% of the underlying  shares on the date which is three months after
the date of grant, and an additional 10% at the end of each  three-month  period
thereafter.  Each such  option  can be  exercised  for five  years  following  a
director's  termination  of  service  to the  extent  it  had  vested  prior  to
termination.  Each automatic  quarterly  stock grant is for the number of shares
obtained by dividing $2,000 by the closing price of the Common Stock on the date
of grant, and is fully vested at grant.

         In November 1996,  pursuant to authorization by the Board of Directors,
the Company  granted to Dr. Sklar  options to purchase  10,000  shares of Common
Stock at an exercise  price of $6.375 to  compensate  him for his  services as a
Director,  which options vested 40% on grant with the remaining  options vesting
20% on each of August 4, 1997,  August 4, 1998 and August 4, 1999. Such grant is
a replacement  of options to purchase  10,000 shares of Common Stock  authorized
but not accepted by Dr. Skar in 1994 due to the  conditions of his employment by
Brigham & Women's Hospital,  Inc. In October 1996,  pursuant to authorization by
the Board of Directors, the Company granted options to purchase 10,000 shares of
Common  Stock  at an  exercise  price of  $7.125  per  share to Mr.  de Bruin in
replacement of options issued in June 1993 which were due to expire in June 2000
and were 60% vested as of October 1996 with the remaining options vesting 20% on
each of June 4, 1997 and June 4, 1998. These replacement  options vested 100% in
October 1996 and expire ten years from the date of grant.

         Messrs.  Sandberg and Johnson and Dr.  Amberson  received no additional
compensation during 1996 for their services as directors of the Company.



<PAGE>

Information Regarding Executive Officers

         David R.  Schreiber,  age 37,  has  served  as Senior  Vice  President,
Finance,  Chief  Financial  Officer and Corporate  Secretary since November 1996
when he joined the Company.  Formerly,  Mr.  Schreiber was with Corning Clinical
Laboratories  for 10 years,  serving most recently as Vice President and General
Manager of the laboratory's  Midwest region.  Mr. Schreiber holds an M.B.A. from
Northern Illinois University.

         Robert C.  Verfurth,  age 37,  joined the Company in February 1989 as a
Sales  Representative.  He  subsequently  served  as  Southeast  Regional  Sales
Manager, National Accounts Manager, and Director of Sales. He has served as Vice
President,  Sales since December 1996. Before joining the Company,  Mr. Verfurth
was a  captain  in the U.S.  Air  Force.  Mr.  Verfurth  holds an M.S.  from the
University of Southern California.

         James T. Barry,  age 35,  joined the Company in July 1989 as  Corporate
Recruiter and subsequently  served as Director of Managed Care. He has served as
Vice President of Marketing & Technology since December 1996. Before joining the
Company,  Mr. Barry was a major in the U.S. Marine Corps. Mr. Barry holds a B.A.
from Rhode Island College.

         Steven T. Clayton,  age 30, has served as Vice  President,  Information
Services  since he joined the  Company in  December  1996.  Prior to joining the
Company,  Mr.  Clayton was with  Corning  Clinical  Laboratories  for nine years
serving most recently as the Midwest Regional  Director of Information  Systems.
Mr. Clayton holds an A.S.M. from Thomas Edison State College.

         For information with respect to Mr. Johnson and Dr.  Amberson,  who are
also directors,  see ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT
- - Information Regarding Directors.

Section 16(a) Beneficial Ownership Reporting Compliance

         Section  16(a) of the  Securities  Exchange  Act of 1934  requires  the
Company's  directors and executive  officers,  and persons who own more than ten
percent of a registered class of the Company's equity  securities,  to file with
the Securities and Exchange  Commission initial reports of ownership and reports
of changes in  ownership  of Common  Stock and other  equity  securities  of the
Company.  Officers,  directors  and greater  than ten percent  shareholders  are
required  to furnish the  Company  with  copies of all Section  16(a) forms they
file.

         To the  Company's  knowledge,  based  solely on review of the copies of
such reports furnished to the Company and representations  that no other reports
were required  during the fiscal year ended December 31, 1996, all Section 16(a)
reporting  requirements  applicable to its officers,  directors and greater than
ten percent beneficial shareholders were complied with except for the following:
Messrs. Johnson, Schreiber, Clayton, Verfurth and Barry each were late in filing
their  initial  Form  3  when  becoming  subject  to the  Section  16  reporting
requirements.  Drs.  Amberson and Sklar each filed a late report with respect to
one  transaction.  Mr.  Gilbert filed a late report with respect to five outside
director option grants that became  effective upon  shareholder  approval of the
1996 Stock  Incentive Plan at the Company's  Annual Meeting of  Shareholders  on
October 24, 1996.


<PAGE>

ITEM 11. EXECUTIVE COMPENSATION

         The  following  table  sets  forth  information  with  respect  to  the
following named executive officers: (i) the person who served as Chief Executive
Officer ("CEO") during 1996, (ii) the four executive officers other than the CEO
serving at  December  31, 1996 whose  total  salary and bonus for 1996  exceeded
$100,000,  and (iii) two additional executive officers who terminated employment
with the Company during 1996.

<TABLE>
<CAPTION>
                                                      SUMMARY COMPENSATION TABLE
                                                                                Long Term
                                                 Annual Compensation           Compensation
                                         -----------------------------------   ------------
                                                                                Long Term
                                                                   Other        Securities 
      Name and                                                     Annual       Underlying        All Other    
  Principal Position          Year       Salary   Bonus         Compensation    Options (4)     Compensation
  ------------------          ----       ------   -----         ------------    -----------     ------------

<S>                           <C>      <C>       <C>           <C>              <C>             <C>
Richard A. Sandberg (1)       1996     $212,500  $20,000       $    --               --         $ 3,681 (2)
Chairman of the Board and     1995      212,500   36,975            --               --           3,681
  Chief Executive Officer     1994      203,280   47,902            --           20,000           3,681

Kevin C. Johnson (3)          1996      174,520   50,000 (4)        --          200,000           1,507 (5)
President and Director

David R. Schreiber            1996       29,231   80,000 (6)        --           50,000           1,742 (7)
Sr. Vice President Finance,
Chief Financial Officer and
  Corporate Secretary

James B. Amberson, M.D.       1996      200,013   47,869            --           15,000           2,530 (8)
Senior Vice President,        1995      185,465   36,997            --           25,000           2,104
  Operations and Chief        1994      173,764   39,230            --           31,500          12,889
  Medical Officer and
  Director

Albert A. Luderer, Ph.D. (9)  1996      171,191   29,206            --               --           9,199 (11)
Vice President, Technology    1995      163,369   41,758         4,190 (10)       10,000          8,530
                              1994      155,048   27,110         2,214 (10)       26,000         22,639

Carl R. Iberger(12)           1996       88,587   13,212            --                --          71,318 (13)
Vice President, Finance and   1995      108,952   27,788            --                --           3,144
   Administration and         1994      103,981   17,847            --            26,800           3,465
   Corporate Secretary

Daniel J. Cronin (14)         1996       89,048   13,564            --                --           6,368 (15)
Vice President, Management    1995       91,038   18,995            --             4,000           3,092
  Information Systems         1994       79,615   15,904            --            15,800             726


<PAGE>

<FN>
- ----------
(1)  Mr. Sandberg  ceased serving as Chief  Executive  Officer of the Company in
     May  1996,  while  continuing  to serve as an  employee  holding  the title
     Chairman  of the Board.  As of  February  1997,  Mr.  Sandberg  resigned as
     Chairman of the Board.  He continues to serve as a Director and  consultant
     to the Company.

(2)  The $3,681 indicated for Mr. Sandberg represents  contributions paid by the
     Company pursuant to the Company's 401(K)  Retirement Plan and premiums paid
     by the Company for term life  insurance  which for 1996  amounted to $1,500
     and $2,181, respectively.

(3)  Mr.  Johnson joined the Company as President in May 1996 and was elected to
     the position of Chief Executive Officer in February 1997.

(4)  The  $50,000  indicated  for Mr.  Johnson  represents  a  sign-on  bonus he
     received when he joined the Company in May 1996.

(5)  The  $1,507  indicated  for Mr.  Johnson  represents  premiums  paid by the
     Company for term life insurance.

(6)  The $80,000  indicated  for Mr.  Schreiber  represents  a sign-on  bonus he
     received when he joined the Company in November 1996.

(7)  The $1,742 indicated for Mr. Schreiber represents  relocation costs paid in
     1996.

(8)  The $2,530 indicated for Dr. Amberson represents  contributions paid by the
     Company pursuant to the Company's 401(K)  Retirement Plan and premiums paid
     by the Company for term life  insurance  which for 1996  amounted to $1,500
     and $1,030, respectively.

(9)  Dr. Luderer resigned as Vice President, Technology in January 1997.

(10) The amounts  indicated for 1995 and 1994 for Dr. Luderer are relocation tax
     gross-ups.

(11) The $9,199 indicated for Dr. Luderer includes deferred  compensation  under
     the   Company's   vacation   banking   policy   accrued  for  during  1996,
     contributions paid by the Company pursuant to their 401(K) Retirement Plan,
     and  premiums  paid by the Company for term life  insurance  which for 1996
     amounted to $6,681, $1,300 and $1,218, respectively.

(12) Mr. Iberger resigned as Vice President,  Finance and  Administration and as
     Corporate Secretary in September 1996.

(13) The  $71,318   indicated  for  Mr.   Iberger   represents   severance  pay,
     contributions  paid  by  the  Company  pursuant  to  the  Company's  401(K)
     Retirement  Plan and premiums  paid by the Company for term life  insurance
     which for 1996 amounted to $69,339, $1,500 and $479, respectively.

(14) Mr. Cronin resigned as Vice President,  Management  Information  Systems in
     December 1996.

(15) The $6,368 indicated for Mr. Cronin represents severance pay, contributions
     paid by the Company  pursuant to the Company's  401(K)  Retirement Plan and
     premiums  paid by the  Company  for  term  life  insurance  which  for 1996
     amounted to $5,452, $520 and $396, respectively.
</FN>
</TABLE>


<PAGE>

         Employment and Severance Agreements

         In January  1995,  Mr. Davis  resigned  his  full-time  employment  and
officer  position  with the  Company.  The Company paid  approximately  $257,000
during 1995 and $21,000 during 1996 for severance benefits to Mr. Davis. As part
of the severance agreement,  during 1995 stock options to purchase 69,916 shares
of Common Stock at exercise  prices  ranging from $4.56 to $10.75 were cancelled
and stock  options to  purchase  116,084  shares of Common  Stock with  exercise
prices  ranging from $8.00 to $10.75 were amended to set their exercise price at
$5.25.  These amended  options vested 25% in March 1995 and the remaining 75% in
January 1997.

         The Company  entered into an employment  agreement  with Mr. Johnson on
May 2, 1996 as President of the Company.  The agreement  provides for an initial
base salary of  $275,000  per annum,  the grant of options to  purchase  200,000
shares of Common Stock with a 10-year term and an exercise price of $5.69, stock
grants of 15,000  shares of Common  Stock on each of January 2, 1997 and January
2, 1998 provided Mr. Johnson continues to be employed by the Company,  a signing
bonus of $50,000 and a loan of $150,000.  The loan  carries an interest  rate of
5.9%,  payable  annually,  and is repayable upon  termination  of Mr.  Johnson's
employment  by the  Company.  If Mr.  Johnson  continues  to be  employed by the
Company,  the loan principal will be forgiven at the rate of $2,500 per complete
month of  employment  from  January 31, 1998 through  December  31,  2002.  This
agreement  provides  that  in  the  event  of a  termination  of  Mr.  Johnson's
employment other than for "Cause",  as defined in the agreement,  he is entitled
to receive one year's salary and other benefits.  Subject to the foregoing, this
agreement is subject to termination at will by either party.

         The Company entered into executive  employment  agreements with Richard
A. Sandberg and Dr. James B. Amberson  (the  "Employees")  on September 1, 1996.
Each such  agreement  provides  that in the event of a "Change in Control of the
Company",  as  defined  in the  agreements,  if  the  Employee's  employment  is
terminated other than for "Cause", as defined in the agreements,  he is entitled
to receive  one  year's  salary  and bonus and all his stock  options  will vest
completely.  The  agreements  expire  in  September  2001  and  are  subject  to
successive  automatic  one-year  renewals  thereafter  (unless certain notice is
given).

         The Company also entered into an employment agreement with Dr. James B.
Amberson on  September  1, 1996.  Pursuant to such  agreement,  Dr.  Amberson is
entitled to a salary as  determined  by the  Company  and other  benefits of the
Company.  This  agreement  provides  that in the event of a  termination  of Dr.
Amberson's  employment  for  other  than  "Stated  Cause"  (as  defined  in  the
agreement),  he is  entitled to receive  six months  salary and other  benefits.
Subject to the  foregoing,  this  agreement is subject to termination at will by
either party.

         During  the  third  quarter  1996,  the  Company  recorded  a charge of
$133,933 for  severance  benefits  relating to Messrs.  Iberger and Cronin,  two
officers of the Company who  resigned  their  full-time  employment  and officer
positions in  September  1996 and December  1996,  respectively.  The Company is
paying Mr. Cronin severance  payments of $7,270 per month for the period of four
months  after his  termination  and for the  following  two months if he has not
obtained other  employment.  Mr. Iberger  received a lump sum payment of $60,000
and is  receiving  severance  payments  totaling  approximately  $27,000 for the
period of nine months after his termination.

         The  Company  entered  into  an  employment  agreement  with  David  R.
Schreiber on September 30, 1996 as the Chief  Financial  Officer and Senior Vice
President,  Finance of the Company.  The agreement  provides for an initial base
salary of $190,000 per annum,  the grant of options to purchase 50,000 shares of
Common  Stock with a 10-year  term and an  exercise  price of $6.625,  a signing
bonus of $80,000 and stock  grants of 7,500  shares of Common  Stock on April 1,
1997 if Mr. Schreiber continues to be employed by the Company on such date. This
agreement  provides  that  in the  event  of a  termination  of Mr.  Schreiber's
employment other than for "Cause",  as defined in the agreement,  he is entitled
to receive one year's  salary (and certain other  benefits) if such  termination
occurs  within the first year of  employment  or six months after the Company is
acquired by another  business  entity or six month's  salary (and certain  other
benefits) if such termination occurs after the first year of employment. Subject
to the  foregoing,  this  agreement is subject to  termination at will by either
party.


<PAGE>

         The Company entered into an employment agreement with Steven T. Clayton
on November 18, 1996 as Vice President, Information Services of the Company. The
agreement  provides for an initial base salary of $120,000 per annum,  a signing
bonus of $14,000  and the grant of options to purchase  15,000  shares of Common
Stock with a 10-year term and an exercise price of $7.875.

         Richard A. Sandberg resigned as Chairman of the Board and as an officer
of the Company effective  February 27, 1997. In connection with his resignation,
the Company and Mr.  Sandberg  entered into an  agreement  pursuant to which the
Company agreed to employ Mr.  Sandberg,  and Mr. Sandberg agreed to be employed,
as a consultant to the President  until  February 28, 1998 or his earlier death,
disability, resignation, or termination for cause (as defined in the agreement).
Such agreement  provides for Mr. Sandberg to receive annual base compensation of
$232,000 plus all benefits provided to management employees of the Company other
than participation in management incentive programs.  In addition such agreement
provides  that all options to purchase  Common Stock held by Mr.  Sandberg as of
February 27, 1997 became fully vested on such date to the extent not  previously
vested.  Mr.  Sandberg  also has the right to sell any or all of such options to
the  Company  at any time on or  before  May 28,  1997 for an  amount  per share
subject to the option equal to the difference  between $10.875 and the per share
exercise  price of the option.  If such  agreement is not  otherwise  renewed by
mutual agreement of the Company and Mr. Sandberg,  it terminates by its terms on
February 28, 1998,  in which event for six months  after such  termination,  Mr.
Sandberg  will be entitled to  severance  pay of $19,333 per month plus  medical
insurance premiums and car allowance.  Under these circumstances,  20,000 shares
of Mr.  Sandberg's  stock options will  terminate in May 1998 and 156,000 shares
will  terminate  in  February  2000.  Mr.  Sandberg  has agreed that he will not
compete  with the  Company  within the  United  States for a period of two years
after  the  termination  of his  employment  as a  consultant  pursuant  to this
agreement.

         Stock Options

         The following table shows,  as to the named  executive  officers of the
Company,  information  about option grants in the last fiscal year. The Company,
as of  December  31,  1996,  has not granted  any Stock  Appreciation  Rights to
officers.

<TABLE>
<CAPTION>
                                              OPTION GRANTS IN LAST FISCAL YEAR

                                                                                             Potential Realizable 
                              Number of      % of Total                                         Value at Assumed 
                              Securities       Options                                     Annual Rates of Stock Price
                              Underlying     Granted to   Exercise or                    Appreciation for Option Term
                                Options      Employees    Base Price    Expiration     --------------------------------        
    Name                      Granted(#)(1)   in 1996     ($/Share)        Date             5%($)             10%($)
    ----                      -------------   -------     ---------        ----        -------------       ------------

<S>                           <C>               <C>        <C>          <C>                <C>              <C>
Richard A. Sandberg                --           --             --             --               --                 --
Kevin C. Johnson              200,000(2)        43%        5.6875       05/02/06           715,368          1,812,882
David R. Schreiber             50,000(3)        11%        6.6250       10/01/06           208,321            527,927
James B. Amberson, M.D.        15,000(4)         3%        6.3750       11/04/06            60,138            152,402
Albert A. Luderer, Ph.D.           --           --             --             --               --                 --
Carl R. Iberger                    --           --             --             --               --                 --
Daniel J. Cronin                   --           --             --             --               --                 --

<FN>
- ----------
(1)  Does not  include  options  granted  under  the  Company's  Employee  Stock
     Purchase Plan, which were made available to all employees of the Company on
     a non-discriminatory basis.

(2)  In May 1996, the Company  granted Mr. Johnson  options to purchase  200,000
     shares of Common  Stock at $5.6875  per share  pursuant  to his  employment
     agreement.  These  options  vest 40% in May 1998 and 20%  during  each year
     thereafter.  Upon  termination  of  employment,  all  unvested  options are
     cancelled  and all  vested  options  expire 90 days  after  termination  of
     employment.


<PAGE>

(3)  In October  1996,  the Company  granted Mr.  Schreiber  options to purchase
     50,000  shares  of  Common  Stock  at  $6.625  per  share  pursuant  to his
     employment agreement. These options vest 40% in October 1998 and 20% during
     each year thereafter.  Upon termination of employment, all unvested options
     are cancelled and all vested  options  expire 90 days after  termination of
     employment.

(4)  In November  1996,  the Company  granted  certain  employees  and  officers
     options to  purchase  203,000  shares of Common  Stock at $6.375 per share.
     These  options  vest  40%  in  November  1998  and  20%  during  each  year
     thereafter.  Upon  termination,  all unvested options are cancelled and all
     vested options expire 90 days after termination of employment.

</FN>
</TABLE>

The following table shows aggregate option exercises in the last fiscal year and
fiscal year-end option values for the named executive officers.  The Company, as
of December 31, 1996, has not granted any Stock Appreciation Rights.

<TABLE>
<CAPTION>
                       AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND FY-END OPTION VALUES

                                          Value
                                         Realized                                      Value of Unexercised
                                         (Market               Number of              In-the-Money Options
                                         Price at       Securities Underlying         at FY-End (based on
                                         Exercise             Unexercised                FY-End Price of
                            Shares         less           Options at FY-End(#)           $8.625/share)(1)     
                          Acquired on    Exercise    ----------------------------   ----------------------------
     Name                 Exercise(#)    Price)($)   Exercisable    Unexercisable   Exercisable    Unexercisable
- ---------------------     -----------    ---------   -----------    -------------   -----------    -------------

<S>                        <C>           <C>          <C>             <C>            <C>             <C> 
Richard A. Sandberg             --       $     --     149,024          26,976        $101,160        $  58,140
Kevin C. Johnson                --             --          --         200,000              --          587,500
David R. Schreiber              --             --          --          50,000              --          100,000
James B. Amberson, M.D          --             --      19,340          52,160          78,617          167,555
Albert A. Luderer, Ph.D.    12,800         41,632          --              --              --               --
Carl R. Iberger                 --             --      15,440              --          62,764               --
Daniel J. Cronin             7,920         26,326          --              --              --               --

<FN>
- ----------
(1)  Computed  based upon  difference  between  aggregate  fair market value and
     aggregate exercise price.

</FN>
</TABLE>


          COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

         Dr.  Sklar  served as a member  of the  Compensation  Committee  of the
Company's  Board of  Directors  during  the last  completed  fiscal  year and is
continuing to serve as such in the 1997 fiscal year. In 1995 the Company entered
into a three-year  research  and  development  agreement  with Brigham & Women's
Hospital,  Inc.,  for  which  Dr.  Sklar is  director,  Division  of  Diagnostic
Molecular Biology,  Department of Pathology.  The agreement requires the Company
to make  quarterly  payments of $30,000  totaling  $360,000  in exchange  for an
option to obtain  rights in certain  existing  inventions  as well as inventions
developed  during the course of  research in the areas of cancer  detection  and
diagnosis.  The  research is to be  conducted  by Dr.  Sklar.  The Company  paid
$120,000 and $60,000 in 1996 and 1995,  respectively.  In addition,  the Company
has made payments to Brigham & Women's Hospital, Inc. of $30,000 in each of 1996
and 1995 for  consulting  services by Dr.  Sklar.  As of December 31, 1996,  the
Company has terminated  this  agreement  effective June 30, 1997 and has accrued
$60,000 for future payments in 1997.

<PAGE>

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

Ownership of Voting Stock by Management

         The  following  table  gives  information   concerning  the  beneficial
ownership of the  Company's  Common Stock as of March 14, 1997 by each  director
and each of the executive  officers named in the summary  compensation table and
all current directors and executive officers (as of March 14, 1997) as a group.

<TABLE>
<CAPTION>
                                Total Shares
                                Beneficially    Direct        Right to     Percent of
Beneficial Owners               Owned(1)(2)    Ownership      Acquire(3)    Class(4)
- -----------------               -----------    ---------      ----------    --------

<S>                               <C>             <C>          <C>            <C>
Richard A. Sandberg               201,722         12,773       185,520        3%
Kevin C. Johnson                   28,832         15,000            --        -- (5)
David R. Schreiber                     --             --            --        -- (5)
James B. Amberson, M.D.            58,344         15,652        28,860        -- (5)
Albert A. Luderer, Ph.D.               --            --             --        -- (5)
Carl R. Iberger                    17,390         17,390            --        -- (5)
Daniel J. Cronin                       --             --            --        -- (5)
John P. Davis                     235,267        116,455       118,812        4%
Walter O. Fredericks                6,863            235         6,628        -- (5)
Jeffrey L. Sklar                    6,963            235         6,728        -- (5)
G. S. Beckwith Gilbert          1,802,314      1,800,235         2,079        28%(6)

All current directors and 
  executive officers as a 
  group (11 persons)            2,316,067      1,961,637       351,001        34%

<FN>
- ----------
(1)  The information as to beneficial ownership is based on statements furnished
     to the Company by its  executive  officers and  directors.  Each  executive
     officer and director has sole voting and sole investment power with respect
     to his  respective  shares  listed  above,  except as  follows:  The shares
     reported for Mr. Gilbert  include  121,951 shares which are held by a trust
     of which Mr.  Gilbert is a trustee,  as to which Mr.  Gilbert shares voting
     and investment powers.  Amounts shown for Messrs.  Sandberg and Johnson and
     Dr. Amberson include 13,832 shares held in the Company's 401(K)  Retirement
     Plan, as to which such officers share voting power as trustees of such plan
     and each individual plan participant has investment  power,  subject to the
     terms of such plan,  of the shares in his  account;  such  amount  includes
     10,403 shares in Mr. Sandberg's  account.

(2)  Includes shares listed under the captions "Direct  Ownership" and "Right to
     Acquire",  as well as shares held in the Company's  401(K)  Retirement Plan
     which are beneficially  owned but as to which the named individual or group
     has no economic interest.

(3)  Individuals currently have the right to acquire these shares within 60 days
     of March 14,  1997 by the  exercise of stock  options or through  purchases
     under the Company's Employee Stock Purchase Plan.

(4)  For the purposes of this table,  "Percent of Class" held by each individual
     has  been  calculated  based  on a  total  class  equal  to the  sum of (i)
     6,449,270  shares of Common Stock issued and  outstanding on March 14, 1997
     plus (ii) for such  individual the number of shares of Common Stock subject
     to stock options or warrants presently  exercisable,  or exercisable within
     60 days after March 14, 1997, held by that individual, and which percent is
     rounded to the nearest whole number.

(5)  Owns less than 1% of the outstanding Common Stock.

(6)  As of March 14, 1997,  Mr. Gilbert cannot vote,  without  restriction,  any
     Common Stock or other voting securities of the Company  beneficially  owned
     by him  representing  greater  than 20% of the  total  voting  power of the
     Company's  voting  securities  outstanding  from time to time, or 1,289,854
     votes as of March 14, 1997.  As of March 14,  1997,  any votes in excess of
     1,289,854  represented  by Common Stock or other voting  securities  of the
     Company  beneficially  owned by Mr. Gilbert as of such date are required to
     be voted in proportion to the votes cast by all other  shareholders  of the
     Company.
</FN>
</TABLE>

<PAGE>

Ownership of Voting Stock by Certain Beneficial Owners

         The  following  table sets forth  information  with respect to the only
persons who, to the best  knowledge of the Company's  management as derived from
schedules 13F, 13D and 13G filed by such persons,  beneficially  owned more than
five  percent of the Common  Stock of the Company as of March 14,  1997.  Unless
otherwise indicated below, each person included in the table has sole voting and
investment power with respect to all shares included therein.

<TABLE>
<CAPTION>
                                                                       Amount
                                                                    and Nature
                              Name and Address of                  of Beneficial        Percent
  Title of Class               Beneficial Owner                      Ownership        of Class(1)
  --------------               ----------------                      ---------        -----------

<S>                        <C>                                      <C>                  <C>
DIANON Common Stock        G.S. Beckwith Gilbert et al              1,802,314(2)         28%(3)
                           35 Vista Drive
                           Greenwich, CT 06830

DIANON Common Stock        Oracle Management Partners, Inc.           461,328             7%
                           and Affiliates
                           712 E 5th Avenue - 45th Floor
                           New York, NY 10019

DIANON Common Stock        John M. Bryan et al                        356,412             6%
                           Bryan and Edwards
                           600 Montgomery Street - 35th Floor
                           San Francisco, CA 94111

<FN>
- ----------
(1)  For the purposes of this table,  "Percent of Class" held by each individual
     has  been  calculated  based  on a  total  class  equal  to the  sum of (i)
     6,449,270  shares of Common Stock issued and  outstanding on March 14, 1997
     plus (ii) for such  individual the number of shares of Common Stock subject
     to stock options or warrants presently  exercisable,  or exercisable within
     60 days after March 14, 1997, held by that individual, and which percent is
     rounded to the nearest whole number.

(2)  Mr. Gilbert has shared voting and investment  power with respect to 121,951
     shares included in the table above.

(3)  As of March 14, 1997,  Mr. Gilbert cannot vote,  without  restriction,  any
     Common Stock or other voting securities of the Company  beneficially  owned
     by him  representing  greater  than 20% of the  total  voting  power of the
     Company's  voting  securities  outstanding  from time to time, or 1,289,854
     votes as of March 14, 1997.  As of March 14,  1997,  any votes in excess of
     1,289,854  represented  by Common Stock or other voting  securities  of the
     Company  beneficially  owned by Mr. Gilbert as of such date are required to
     be voted in proportion to the votes cast by all other  shareholders  of the
     Company.
</FN>
</TABLE>

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         See  Item  11  -  Executive  Compensation  -  "Compensation   Committee
Interlocks  and  Insider  Participation"  and  Notes  6 and 14 of the  Company's
consolidated financial statements included herewith.

         As part of the process to recruit a new executive,  the Company lent an
affiliate of Mr.  Sandberg  $75,000 in March 1995 at 8% interest.  Such loan was
repaid in full with interest in March 1996.

         For description of a loan from the Company to Mr. Johnson,  see Item 11
- - Executive Compensation "Employment and Severance Agreements".

         In January 1997,  the Company  purchased  89,000 shares of Common Stock
from Richard A. Sandberg at a price of $8.50 per share.


<PAGE>

                                    PART IV

ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

(a)    Financial Statements, Financial Statement Schedules Filed.

       1)     Financial  Statements - See  accompanying  Consolidated  Financial
              Statements and Schedules, Pages F-1 through F-18.

       2)     Financial  Statement  Schedules  - See  accompanying  Consolidated
              Financial Statements and Schedules, Pages F-1 through F-18.

       3)     Exhibits - Refer to 14(c) below.

(b)    The  Company  filed no reports on Form 8-K in the fourth  quarter of 1996
       with the Securities and Exchange Commission.

(c)    Exhibit Index

       3.1    Restated  Certificate of Incorporation of the Company,  as amended
              through June 12, 1991 (incorporated by reference to Exhibit 3.1 of
              the Registrant's Registration Statement No. 33-41226).

       3.2    Restated  By-Laws of the Company,  as amended  through October 24,
              1996 (incorporated by reference to Exhibit 4.2 of the Registrant's
              Registration Statement No. 333-18817).

       10.1   Consulting  Agreement,   dated  August  4,  1989,  between  DIANON
              Systems,  Inc. and Nonda Katopodis  (incorporated  by reference to
              Exhibit  10.7  of  the  Registrant's  Registration  Statement  No.
              33-41226).**

       10.2   Executive Vesting  Agreement,  dated as of June 11, 1991,  between
              DIANON  Systems,  Inc.  and  James B.  Amberson  (incorporated  by
              reference  to  Exhibit  10.13  of  the  Registrant's  Registration
              Statement No. 33-41226).**

       10.3   1991 Stock  Incentive Plan  (incorporated  by reference to Exhibit
              10.17 of the Registrant's Registration Statement No. 33-41226).**

       10.4   Management  Incentive Plan  (incorporated  by reference to Exhibit
              10.18 of the Registrant's Registration Statement No. 33-41226).**

       10.5   Stock Option Grant to Walter O.  Fredericks,  dated April 27, 1990
              (incorporated  by reference to Exhibit  10.23 of the  Registrant's
              Registration Statement No. 33-41226).**

       10.6   Stock  Option  Grant to Richard A.  Sandberg,  dated June 12, 1991
              (incorporated  by reference to Exhibit  10.24 of the  Registrant's
              Registration Statement No. 33-41226).**

       10.7   Stock  Option  Grant to Richard A.  Sandberg,  dated June 12, 1991
              (incorporated  by reference to Exhibit  10.25 of the  Registrant's
              Registration Statement No. 33-41226).**

       10.8   Lease  Agreement,  made as of February  14, 1989,  between  Watson
              Boulevard  Development Limited Partnership,  as lessor, and DIANON
              Systems,  Inc.,  as  lessee,  for  premises  located at 200 Watson
              Boulevard  (incorporated  by  reference  to  Exhibit  10.29 of the
              Registrant's Registration Statement No. 33-41226).

       10.9   License  Agreement,  dated June 9, 1983,  between  Sloan-Kettering
              Institute  for  Cancer  Research  and  N-K  Laboratories   Limited
              Partnership  (incorporated  by reference  to Exhibit  10.30 of the
              Registrant's Registration Statement No. 33-41226).

       10.10  License  Agreement,  dated July 29, 1987,  between  University  of
              Rochester and DIANON Systems,  Inc.  (incorporated by reference to
              Exhibit  10.32  of the  Registrant's  Registration  Statement  No.
              33-41226).

       10.11  Development  Agreement,  effective  September  25,  1987,  between
              Connecticut  Product  Development  Corporation and DIANON Systems,
              Inc.   (incorporated   by  reference  to  Exhibit   10.33  of  the
              Registrant's Registration Statement No. 33-41226).



<PAGE>

(c)    Exhibit Index (continued)

       10.12  Stock  Option  Grant to James B.  Amberson,  dated  April 23, 1991
              (incorporated  by reference  to Exhibit  28.1 to the  Registrant's
              Quarterly  Report on Form 10-Q for the quarter ended September 30,
              1991).**

       10.13  Stock Option Grant to Richard A. Sandberg, dated June 12, 1991, as
              amended  (incorporated  by  reference  to  Exhibit  10.37  to  the
              Registrant's  Annual  Report  on  Form  10-K  for the  year  ended
              December 31, 1991).**

       10.14  Asset Purchase  Agreement,  dated April 30, 1993, by and among the
              Registrant  and Molecular  Oncology,  Inc.,  and  Oncologix,  Inc.
              (incorporated by reference to Exhibit 1.1 to the Registrant's Form
              8-K dated April 30, 1993,  filed with the  Securities and Exchange
              Commission on May 14, 1993).

       10.15  Asset  Purchase  Agreement,  dated June 29, 1993, by and among the
              Registrant  and  Collaborative  Research,  Inc.  (incorporated  by
              reference to Exhibit 1.2 to the  Registrant's  Form 8-K dated June
              29, 1993,  filed with the  Securities  and Exchange  Commission on
              July 13, 1993).

       10.16  Term  Loan  Agreement,  dated  July 14,  1993,  by and  among  the
              Registrant and the Union Trust Company  (incorporated by reference
              to Exhibit 10.34 to the Registrant's  Annual Report on Form 10-K/A
              Amendment 1 for the year ended  December 31, 1993,  filed with the
              Securities and Exchange Commission on April 28, 1994).

       10.17  Rights  Agreement,   dated  April  29,  1994,  by  and  among  the
              Registrant and American  Stock and Trust Company,  as Rights Agent
              (incorporated by reference to Exhibit 1 to the  Registrant's  Form
              8-K dated April 29, 1994,  filed with the  Securities and Exchange
              Commission on May 9, 1994).

       10.18  Severance  Agreement,  dated  January 20,  1995,  by and among the
              Registrant and John P. Davis (incorporated by reference to Exhibit
              10.36 to the Registrant's  Annual Report on Form 10-K for the year
              ended  December 31, 1995,  filed with the  Securities and Exchange
              Commission on March 29, 1996).**

       10.19  Employment  Agreement,  dated May 3, 1996, by the  Registrant  and
              Kevin C. Johnson  (incorporated  by reference to Exhibit  10.37 to
              the  Registrant's  Quarterly  Report on Form 10-Q for the  quarter
              ended June 30, 1996).**

       10.20  Executive  Employment  Agreement,  dated September 1, 1996, by the
              Registrant and Richard A. Sandberg  (incorporated  by reference to
              Exhibit 10.38 to the  Registrant's  Quarterly  Report on Form 10-Q
              for the quarter ended September 30, 1996).**

       10.21  Employment  Agreement,  dated September 1, 1996, by the Registrant
              and Dr. James B.  Amberson  (incorporated  by reference to Exhibit
              10.39 to the  Registrant's  Quarterly  Report on Form 10-Q for the
              quarter ended September 30, 1996).**

       10.22  Executive  Employment  Agreement,  dated September 1, 1996, by the
              Registrant and Dr. James B. Amberson (incorporated by reference to
              Exhibit 10.40 to the  Registrant's  Quarterly  Report on Form 10-Q
              for the quarter ended September 30, 1996).**

       10.23  Severance  Agreement,  dated September 27, 1996, by the Registrant
              and Carl R. Iberger (incorporated by reference to Exhibit 10.41 to
              the  Registrant's  Quarterly  Report on Form 10-Q for the  quarter
              ended September 30, 1996).**

       10.24  Employment  Agreement,  dated September 30,1996, by the Registrant
              and David R. Schreiber (incorporated by reference to Exhibit 10.42
              to the Registrant's  Quarterly Report on Form 10-Q for the quarter
              ended September 30, 1996).**

       10.25  Employment  Agreement,  dated November 18, 1996, by the Registrant
              and Steven T. Clayton (filed herewith).**

       10.26  Separation  Agreement  dated November 18, 1996, by  the Registrant
              and Daniel J. Cronin, III (filed herewith).**

<PAGE>

(c)    Exhibit Index (continued)

       10.27  Amendment dated as of October 4, 1995 to Rights Agreement dated as
              of April 29,  1994  between  the  Registrant  and  American  Stock
              Transfer  and Trust  Company,  as Rights  Agent  (incorporated  by
              reference  to  Exhibit  No. 1 to the  Registrant's  Form 8-K dated
              October 30, 1996 filed with the Securities and Exchange Commission
              on November 8, 1995).

       10.28  1996 Stock Incentive Plan (incorporated by reference to Appendix A
              to the  Registrant's  Statement  on  Schedule  14A filed  with the
              Securities and Exchange Commission on September 23, 1996).**

       10.29  Stock and Warrant Purchase Agreement, dated as of October 4, 1995,
              among the Gilbert Family Trust,  the G.S.  Beckwith Gilbert I.R.A.
              Contributory  Account,  G.S.  Beckwith  Gilbert and the Registrant
              (filed herewith).

       10.30  Registration Rights Agreement,  dated as of October 4, 1995, among
              the  Gilbert  Family  Trust,  the  G.S.  Beckwith  Gilbert  I.R.A.
              Contributory  Account,  G.S.  Beckwith  Gilbert and the Registrant
              (filed herewith).

       10.31  Warrant No. 1, dated as of October 4, 1995,  by the  Registrant in
              favor of G.S. Beckwith Gilbert (filed herewith).

       10.32  Promissory Note,  dated October 4, 1995, by G.S.  Beckwith Gilbert
              in favor of the Registrant (filed herewith).

       10.33  Stock Option  Grant dated  October 24, 1996 by the  Registrant  to
              Andre de Bruin (filed herewith).**

       10.34  Stock Option  Grant dated  November 4, 1996 by the  Registrant  to
              Jeffrey M. Sklar, M.D. (filed herewith).**

       10.35  Loan  Agreement  dated December 3, 1996 by the Registrant to Kevin
              C. Johnson (filed herewith).**

       10.36  Form of standard Stock Option Grant for outside  directors  (filed
              herewith).**

       10.37  Amendment  to Warrant  Certificate  No. W-1 dated as of October 2,
              1996  between the  Registrant  and G.S.  Beckwith  Gilbert  (filed
              herewith).

       10.38  Severance  Agreement,  dated  February 27, 1997, by the Registrant
              and Richard A. Sandberg (filed herewith).**

       11.1   Statement re: computation of per share earnings. *

       22.1   List of Subsidiaries of the Company  (incorporated by reference to
              Exhibit  22.1  of  the  Registrant's  Registration  Statement  No.
              33-41226).

       23.1   1996 Consent of Arthur Andersen LLP  (incorporated by reference to
              Exhibit 23.1 of the  Registrant's  Annual  Report on Form 10-K for
              the year ended December 31, 1995).

       23.2   1997 Consent of Arthur Andersen LLP (filed herewith).

       27.1   Financial Data Schedule.

- --------------
*      Not applicable or contained elsewhere herein.
 
**     A management contract or compensatory plan or arrangement  required to be
       filed as an exhibit to this form pursuant to Item 14(c) of this report.


<PAGE>

                                   SIGNATURES

         Pursuant to the  requirements  of Section 13 or 15(d) of the Securities
Exchange Act of 1934,  the Registrant has caused this report to be signed on its
behalf by the undersigned, thereunto duly authorized.

DATED:    March 26, 1997

                                      DIANON SYSTEMS, INC.


                                      By:    /s/ KEVIN C. JOHNSON
                                         ----------------------------------
                                         Kevin C. Johnson,
                                         President and Chief Executive Officer


         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
this  report has been  signed  below by the  following  persons on behalf of the
Registrant and in the capacities and on the dates indicated:

       Signature                         Capacity                    Date
       ---------                         --------                    ----


       /s/ KEVIN C. JOHNSON           President and Chief        March 26, 1997
       ----------------------------   Executive Officer
       Kevin C. Johnson               and a Director
                                      (Principal Executive 
                                      Officer)


       /s/ DAVID R. SCHREIBER         Senior Vice President,     March 26, 1997
       ----------------------------   Finance and Chief
       David R. Schreiber             Financial Officer
                                      (Principal Financial 
                                      and Accounting Officer)


       /s/ JAMES B. AMBERSON, MD      Director, Chief Medical    March 26, 1997
       ----------------------------   Officer and Senior Vice
       James B. Amberson, M.D.        President, Operations


       /s/ JOHN P. DAVIS              Chairman of the Board      March 26, 1997
       ----------------------------
       John P. Davis


       /s/ G. S. BECKWITH GILBERT     Director and Chairman      March 26, 1997
       ----------------------------   of the Executive Committee
       G. S. Beckwith Gilbert         


       /s/ RICHARD A. SANDBERG        Director                   March 26, 1997
       ----------------------------       
       Richard A. Sandberg


       /s/ WALTER O. FREDERICKS       Director                   March 26, 1997
       ----------------------------       
       Walter O. Fredericks


       /s/ JEFFREY L. SKLAR, MD PhD   Director                   March 26, 1997
       ----------------------------       
       Jeffrey L. Sklar, M.D., Ph.D.

<PAGE>
                              DIANON SYSTEMS, INC.
            INDEX TO CONSOLIDATED FINANCIAL STATEMENTS AND SCHEDULES

                                                                 PAGE
                                                                 ----

Report of Independent Public Accountants                         F-2

Consolidated Balance Sheets as of 
  December 31, 1996 and 1995                                     F-3 & F-4

Consolidated Statements of Operations for 
  the Years Ended December 31, 1996, 
  1995 and 1994                                                  F-5

Consolidated Statements of Stockholders' 
  Equity for the Years Ended December 31, 
  1996, 1995 and 1994                                            F-6

Consolidated Statements of Cash Flows for the 
  Years Ended December 31, 1996, 1995 and 1994                   F-7 & F-8

Notes to Consolidated Financial Statements                       F-9 to F-17

Schedules:

Report of Independent Public Accountants                         F-18

Schedule II - Valuation and Qualifying Accounts                  F-19

         All other  schedules  called for by  Regulation  S-X have been  omitted
because they are not applicable or because the required  information is included
in the financial statements or notes thereto.


<PAGE>


                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To DIANON Systems, Inc.:

         We have audited the accompanying  consolidated balance sheets of DIANON
Systems,  Inc. (a Delaware corporation) and subsidiaries as of December 31, 1996
and 1995, and the related consolidated  statements of operations,  stockholders'
equity and cash flows for each of the three years in the period  ended  December
31, 1996.  These financial  statements are the  responsibility  of the Company's
management.  Our  responsibility  is to express  an  opinion on these  financial
statements based on our audits.

         We conducted our audits in accordance with generally  accepted auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

         In our opinion,  the  financial  statements  referred to above  present
fairly, in all material respects, the financial position of DIANON Systems, Inc.
and  subsidiaries  as of  December  31,  1996 and 1995  and the  results  of its
operations  and its cash flows for each of the three  years in the period  ended
December 31, 1996 in conformity with generally accepted accounting principles.

                               ARTHUR ANDERSEN LLP

Stamford, Connecticut,
February 27, 1997


































                                      F-2

<PAGE>

                              DIANON SYSTEMS, INC.
                        CONSOLIDATED BALANCE SHEETS AS OF
                           DECEMBER 31, 1996 AND 1995
<TABLE>
<CAPTION>

                                                                     1996             1995
                                                                 ------------     ------------
      ASSETS

CURRENT ASSETS:

     <S>                                                         <C>              <C>         
     Cash and cash equivalents                                   $  7,488,590     $ 10,990,231
     Accounts receivable, net of allowances of 
         $1,056,920 and $786,920, respectively                     15,426,221        9,653,971
     Prepaid expenses and employee advances                         1,189,139        1,071,963
     Prepaid and refundable income taxes                              329,371          168,420
     Inventory                                                        662,567          554,398
     Deferred income tax asset (Note 3)                               677,277          652,328
     Investment in common stock (Note 10)                                  --          135,508
                                                                 ------------     ------------
           Total current assets                                    25,773,165       23,226,819
                                                                 ------------     ------------

PROPERTY AND EQUIPMENT, at cost (Note 4)

     Laboratory and office equipment                               12,233,989       11,068,949
     Leasehold improvements                                         3,612,198        1,717,606
       Less - accumulated depreciation and amortization            (8,606,176)      (6,879,799)
                                                                 ------------     ------------
                                                                    7,240,011        5,906,756
                                                                 ------------     ------------

INTANGIBLE ASSETS, net of accumulated 
     amortization of $2,991,286 and
     $2,731,291, respectively                                         604,313         864,308

DEFERRED INCOME TAX ASSET (Note 3)                                    458,465         178,575

OTHER ASSETS                                                          459,696         278,948
                                                                 ------------     -----------
         TOTAL ASSETS                                             $34,535,650     $30,455,406
                                                                 ============     ===========
</TABLE>



       The accompanying notes to consolidated financial statements are an
                     integral part of these balance sheets.















                                      F-3

<PAGE>

                              DIANON SYSTEMS, INC.
                        CONSOLIDATED BALANCE SHEETS AS OF
                           DECEMBER 31, 1996 AND 1995

<TABLE>
<CAPTION>

                                                                     1996             1995
                                                                 -----------      ------------
         LIABILITIES AND STOCKHOLDERS' EQUITY

CURRENT LIABILITIES:

     <S>                                                        <C>              <C>         
     Accounts payable                                           $  1,903,448     $  2,034,277
     Accrued employee bonuses and commissions                      1,351,616        1,442,826
     Accrued employee stock purchase plan                            549,540           48,914
     Current portion of capitalized lease
        obligations (Note 4)                                          26,107           38,466
     Current portion of note payable (Note 11)                       650,154          916,150
     Other accrued expenses                                        3,234,295        1,772,216
                                                                ------------     ------------
           Total current liabilities                               7,715,160        6,252,849
                                                                ------------     ------------
LONG-TERM PORTION OF CAPITALIZED LEASE OBLIGATIONS
     (Note 4)                                                         69,611           34,413

LONG-TERM NOTE PAYABLE (Note 11)                                          --          650,154

DEFERRED INCOME TAX LIABILITY (Note 3)                               201,951           65,651
                                                                ------------     ------------
           Total liabilities                                       7,986,722        7,003,067
                                                                ------------     ------------


COMMITMENTS (Notes 4 and 8)

STOCKHOLDERS' EQUITY (Notes 5 and 7):

     Common stock, par value $.01 per share,
         20,000,000 shares authorized,6,712,774
         and 6,311,451 shares issued and
         outstanding at December 31, 1996
         and 1995, respectively                                       67,128           63,115
     Additional paid-in capital                                   27,965,560       26,609,657
     Accumulated deficit                                            (554,317)      (2,724,433)
     Common stock held in treasury, at cost -
         117,196 and 50,000 shares at
         December 31, 1996 and 1995, respectively                   (929,443)        (200,000)
     Shareholder note receivable                                          --         (296,000)
                                                                ------------     ------------
         Total stockholders' equity                               26,548,928       23,452,339
                                                                ------------     ------------
         TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY             $ 34,535,650     $ 30,455,406
                                                                ============     ============

</TABLE>

       The accompanying notes to consolidated financial statements are an
                     integral part of these balance sheets.





                                      F-4

<PAGE>

                                      DIANON SYSTEMS, INC.
                             CONSOLIDATED STATEMENTS OF OPERATIONS
                      FOR THE YEARS ENDED DECEMBER 31, 1996, 1995 AND 1994

<TABLE>
<CAPTION>
                                                        1996           1995          1994
                                                    -----------    -----------    -----------

<S>                                                 <C>            <C>            <C>        
NET REVENUES                                        $55,998,995    $45,700,321    $41,016,949

COST OF SALES                                        26,897,576     20,390,742     16,717,401
                                                    -----------    -----------    -----------

    GROSS PROFIT                                     29,101,419     25,309,579     24,299,548

SELLING, GENERAL, AND ADMINISTRATIVE
    EXPENSES                                         22,443,192     19,619,773     17,504,722

RESEARCH AND DEVELOPMENT EXPENSES                     3,157,846      5,255,032      4,511,708
                                                    -----------    -----------    -----------
    INCOME FROM OPERATIONS                            3,500,381        434,774      2,283,118

INTEREST INCOME                                         384,306        317,353        103,531

INTEREST EXPENSE                                         77,466        136,113        193,759
                                                    -----------    -----------    -----------
    INCOME BEFORE PROVISION FOR INCOME TAXES          3,807,221        616,014      2,192,890

PROVISION FOR INCOME TAXES (Note 3)                   1,637,105        508,918        831,796
                                                    -----------    -----------    -----------
    NET INCOME                                      $ 2,170,116    $   107,096    $ 1,361,094
                                                    ===========    ===========    ===========
    PRIMARY AND FULLY DILUTED EARNINGS PER SHARE    $       .34    $       .02            .26
                                                    ===========    ===========    ===========
</TABLE>


       The accompanying notes to consolidated financial statements are an
                       integral part of these statements.
























                                              F-5

<PAGE>

<TABLE>
<CAPTION>
                                                       DIANON SYSTEMS, INC.
                                          CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
                                       FOR THE YEARS ENDED DECEMBER 31, 1996, 1995, AND 1994

                                                                        Unrealized   Foreign   Common Stock
                                                Additional               Holdings    Currency     Held in     Shareholder
                                Common Stock     Paid-In    Accumulated   Gains/    Translation  Treasury,       Note
                              Shares    Amount   Capital      Deficit    (Losses)    Adjustment   at Cost     Receivable    Total
                             --------- -------  ----------  -----------  ---------  ----------- ------------ -----------  ---------

<S>                          <C>       <C>      <C>         <C>          <C>        <C>         <C>          <C>         <C>
BALANCE, December 31, 1993   5,246,448 $52,465  $21,529,478 ($4,192,623) ($242,281) $    --     $     --     $     --   $17,147,039
  Stock options exercised       50,431     504       59,053          --         --       --           --           --        59,557
  Stock compensation
    expense - stock options         --      --        3,411          --         --        --          --           --         3,411
  Unrealized holding gains          --      --           --          --    151,898        --          --           --       151,898
  Changes in foreign
    currency translation
    adjustment                      --      --           --          --         --   (58,938)         --           --       (58,938)
  Net Income                        --      --           --   1,361,094         --        --          --           --     1,361,094
                             --------- -------  -----------  ----------  ---------  --------    --------     --------   -----------
BALANCE, December 31, 1994   5,296,879  52,969   21,591,942  (2,831,529)   (90,383)  (58,938)         --           --    18,664,061
  Stock options exercised       14,572     146       59,286          --         --        --          --           --        59,432
  Issuance of common stock
    and warrants net of
    issuance costs           1,000,000  10,000    4,976,443          --         --        --          --           --     4,986,443
  Common stock held in
    treasury                        --      --           --          --         --        --    (200,000)          --      (200,000)
  Shareholder note
    receivable                      --      --           --          --         --        --          --     (296,000)     (296,000)
  Stock compensations
    expense -stock
    options                         --      --      (18,014)         --         --        --          --           --       (18,014)
  Write-off of unrealized
    holding losses                  --      --           --          --     90,383        --          --           --        90,383
  Write-off of foreign
    currency translation
    adjustment                      --      --           --          --         --    58,938          --           --        58,938
  Net Income                        --      --           --     107,096         --        --          --           --       107,096
                             --------- -------  -----------  ----------  ---------  --------   --------- ------------   -----------
BALANCE, December 31, 1995   6,311,451  63,115   26,609,657  (2,724,433)        --        --    (200,000)    (296,000)   23,452,339
  Stock options exercised       23,621     236      107,476          --         --        --          --           --       107,712
  Exercise of warrants net
    of exercise costs          800,000   3,777    1,536,540          --         --        --   2,478,889           --     4,019,206
  Common stock held in
    treasury                        --      --           --          --         --        --  (3,208,332)          --    (3,208,332)
  Extinguishment of
    shareholder note
    receivable                      --      --     (296,000)         --         --        --          --      296,000            --
  Stock compensation
    expense - stock
    options                         --      --        7,887          --         --        --          --           --         7,887
  Net Income                        --      --           --   2,170,116         --        --          --           --     2,170,116
                             --------- -------  -----------  ----------  ---------  --------   --------- ------------   -----------
BALANCE, December 31, 1996   7,135,072 $67,128  $27,965,560  ($ 554,317)        --       --     ($929,443)          --  $26,548,928
                             ========= =======  ===========  ==========  =========  ======== ============= ============ ===========


                                The accompanying notes to consolidated financial statements are an
                                                integral part of these statements.





                                                                 F-6
</TABLE>

<PAGE>

                              DIANON SYSTEMS, INC.
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1995 AND 1994


<TABLE>
<CAPTION>

                                                    1996          1995          1994
                                                 -----------   -----------   -----------
CASH FLOWS FROM OPERATING ACTIVITIES:

<S>                                              <C>           <C>           <C>        
    Net income                                   $ 2,170,116   $   107,096   $ 1,361,094
Adjustments to reconcile net income
  to net cash provided by (used
  in) operations -
  Non-cash charges
     Depreciation and amortization                 2,463,325     2,758,611     1,951,726
     Stock compensation expense                        7,887       (18,014)        3,411
     Loss on disposal of fixed assets                 27,240        56,266       111,969
     Investment write-down                            61,846       529,625            --
     (Increase) decrease in deferred
       tax asset                                    (304,839)     (108,425)      147,785
     Increase in deferred tax liability              136,300        11,214        54,437
Changes in other current assets and liabilities
  (Increase) decrease in accounts receivable      (5,772,250)    1,345,427    (2,178,403)
  (Increase) decrease in prepaid expenses and
    employee advances                               (278,127)     (147,728)      440,951
  (Increase) decrease in inventory                  (108,169)      158,643       213,116
  (Increase) in other assets                        (320,176)      (29,075)     (102,273)
  Increase in accounts payable and other
    accrued liabilities                            1,751,788     1,358,348       464,849
  (Decrease) increase in restructuring
    reserves                                         (11,123)       66,148      (624,309)
                                                  ----------    ----------    ----------
  Net cash (used in) provided by operating
    activities                                      (176,182)    6,088,136     1,844,353
                                                  ----------    ----------    ----------

CASH FLOWS FROM INVESTING ACTIVITIES:

  Capital expenditures                            (3,431,895)   (2,290,720)   (1,557,160)
  Proceeds from the sale of stock
    held for investment                               73,661        14,867            --
  Proceeds from the sale of fixed
    assets                                             7,500        10,040         8,000
                                                  ----------    ----------    ----------
  Net cash (used in) investing activities        ($3,350,734)  ($2,265,813)  ($1,549,160)
                                                  ----------    ----------    ----------
</TABLE>


       The accompanying notes to consolidated financial statements are an
                       integral part of these statements.










                                      F-7
<PAGE>

                              DIANON SYSTEMS, INC.
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
        FOR THE YEARS ENDED DECEMBER 31, 1996, 1995 AND 1994 (CONTINUED)


<TABLE>
<CAPTION>
                                            1996           1995           1994
                                        -----------     ----------     ---------

CASH FLOWS FROM FINANCING ACTIVITIES:

  <S>                                      <C>            <C>           <C>      
  Repayments of note payable               (916,150)      (862,446)     (810,511)
  Net borrowings (repayments)
    of capitalized lease
    obligations                              22,839        (53,614)      (67,809)
  Net proceeds from issuance
    of common stock and
    warrants                                     --      4,690,443            --
  Net proceeds from exercise
    of warrants                           4,019,206             --            --
  Purchase of common stock
    held in treasury                     (3,208,332)      (200,000)           --
  Exercise of stock options                 107,712         59,432        59,557
                                        -----------     ----------     ---------
    Net cash provided by (used in)
      financing activities                   25,275      3,633,815      (818,763)
                                        -----------     ----------     ---------

    Net (decrease) increase in
      cash and cash equivalents          (3,501,641)     7,456,138      (523,570)

CASH AND CASH EQUIVALENTS,
  beginning of year                      10,990,231      3,534,093     4,057,663

CASH AND CASH EQUIVALENTS,
  end of year                          $  7,488,590   $ 10,990,231   $ 3,534,093
                                       ============   ============   ===========
</TABLE>



<TABLE>
<CAPTION>
                                            1996           1995           1994
                                        -----------     ----------     ---------
SUPPLEMENTAL CASH FLOWS DISCLOSURES:

  Cash paid during the year:

    <S>                                <C>            <C>            <C>        
    Interest                           $    77,782    $    135,644   $   191,879
    Income taxes                         1,712,200         588,149       311,689
</TABLE>


During 1996, the Company received $4,000,000 in cash for the exercise of 800,000
warrants and  extinguished a note  receivable of $296,000.  (See Note 14.)

       The accompanying notes to consolidated financial statements are an
                       integral part of these statements.


                                      F-8

<PAGE>

                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

(1)      The Company

         DIANON Systems,  Inc. (the "Company") is a provider of testing services
and diagnostic information primarily to physicians who treat and diagnose cancer
throughout the United States.  The Company has  established a national sales and
marketing  organization to market a complete line of anatomic  pathology testing
services  as  well as  specialized  clinical  chemistry  tests  and  information
services  directly to  physicians,  payors and  managed  care  organizations.  A
significant  portion of the  services  provided  by the  Company are paid for by
either  the  patients'  Medicare  or private  medical  insurance  policies.  The
remaining services are generally paid for by physicians or hospitals directly.

(2)      Significant Accounting Policies

Principles of Consolidation -

         The  consolidated  financial  statements  include  the  accounts of the
Company and all of its subsidiaries.  All significant intercompany  transactions
have been eliminated in consolidation.

Use of Estimates -

         The  preparation of financial  statements in conformity  with generally
accepted  accounting  principles  requires  management  to  make  estimates  and
assumptions  that  affect the  reported  amounts of assets and  liabilities  and
disclosure of  contingent  assets and  liabilities  at the date of the financial
statements  and the  reported  amounts  of  revenues  and  expenses  during  the
reporting period. Actual results could differ from those estimates.

Cash and Cash Equivalents -

         The Company  considers all highly liquid  instruments  purchased with a
maturity of three  months or less to be cash  equivalents.  At December 31, 1996
and  1995,   the  Company  had   approximately   $6  million  and  $11  million,
respectively, invested in short-term U.S. treasury funds with maturities of less
than three months. The carrying amount of the cash equivalents  approximates its
fair value due to the relatively short period to maturity of these  instruments.
The  Company  is  obligated  to keep a  compensating  balance  of $2  million in
accordance with its loan agreement. (See Note 11).

Inventory -

         Inventory consists primarily of bulk reagents, specimen collection kits
and  devices.  Inventories  are stated at the lower of cost or  market.  Cost is
determined using the first-in, first-out method.

Intangible Assets -

         Intangible  assets  are  amortized  on a  straight  line basis over the
respective economic life as follows:

                           YEARS
                           -----

                  Unamortized customer lists         7
                  Noncompete agreement               5

         The Company  periodically  reviews the anticipated  revenues related to
intangible assets to determine whether any adjustment to their carrying value is
necessary.  During 1996 and 1995, the Company recorded accelerated  amortization
charges  of  approximately  $44,000  and  $765,000,  respectively,  based on the
Company's revised estimate of future benefits from a customer list.


                                      F-9
<PAGE>

                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

Revenue Recognition -

         Revenues are  recognized in the period in which  services are provided.
Revenues subject to Medicare, direct physician and hospital billing are based on
fixed reimbursement fee schedules. All remaining revenues subject to third-party
reimbursement  are recorded at estimated  reimbursable  amounts based on Uniform
Customary Charges.

Depreciation and Amortization -

         Laboratory and office equipment are depreciated using the straight-line
method  on a  useful  life of two to seven  years.  Leasehold  improvements  are
amortized over the shorter of their  economic  useful life or the remaining life
of the lease.

Research and Development -

         Research and development costs are charged to expense as incurred.

Income Taxes -

         The Company  utilizes the  liability  method of  accounting  for income
taxes  as  set  forth  in  Statement  of  Financial   Accounting  Standard  109,
"Accounting  for Income  Taxes".  Under this method,  deferred  income taxes are
determined  based on the  difference  between the financial  statements  and tax
bases  of  assets  and  liabilities   using  presently  enacted  tax  rates  and
regulations.

Earnings Per Share -

         Primary  earnings  per share has been  computed  based on the  weighted
average number of common shares and common equivalent shares  outstanding during
each year  (6,330,553,  5,550,615 and 5,310,174 for the years ended December 31,
1996, 1995 and 1994, respectively). Common equivalent shares outstanding include
the common equivalent shares calculated for warrants and stock options under the
treasury stock method.

Foreign Currency Translation -

         In 1995, the Company charged to income the Germany currency translation
adjustment  of $160,567 due to  management's  decision to  discontinue  European
based operations.  During prior periods, assets and liabilities of the Company's
foreign  subsidiaries  were translated into U.S. dollars using the exchange rate
in effect at the balance sheet date. Results of operations were translated using
the average  exchange rate  prevailing  for the period.  The effects of exchange
rate  fluctuations on translating  foreign  currency assets and liabilities into
U.S.  dollars  were  included  in net income for all of the  Company's  European
subsidiaries except Germany. (See Note 7).

Reclassifications -

         Certain  reclassifications  have been  made to prior  year  amounts  to
conform to the classifications used in the current year presentation.









                                      F-10
<PAGE>
                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

(3)      Income Taxes

         The income tax provisions for the years ended December 31, 1996,  1995,
and 1994 consist of the following:

<TABLE>
<CAPTION>
                                       Year Ended December 31
                                  ----------------------------------
                                     1996          1995       1994
                                  -----------   ---------   --------
<S>                               <C>           <C>         <C>     
Current
    Federal                       $ 1,387,967   $ 461,361   $539,401
    State                             446,091     152,593    208,255
                                  -----------   ---------   --------
         Total Current              1,834,058     613,954    747,656
                                  -----------   ---------   --------
Deferred
    Federal                          (152,112)    (33,532)    71,477
    State                             (44,841)    (71,504)    12,663
                                  -----------   ---------   --------
         Total Deferred              (196,953)   (105,036)    84,140
                                  -----------   ---------   --------
Total provision for income
  taxes                           $ 1,637,105   $ 508,918   $831,796
                                  ===========   =========   ========
</TABLE>

         The reasons for the  differences  between the  statutory  and effective
rates are as follows:

<TABLE>
<CAPTION>
                                       Year Ended December 31
                                  ----------------------------------
                                     1996          1995       1994
                                  -----------   ---------   --------
<S>                               <C>           <C>         <C>     
Statutory federal income
  tax rate                        34.0%         34.0%       34.0%
State taxes, net of federal
  tax benefit                      7.0           8.7         6.7
Utilization of research
  & development credits             --          (5.7)       (7.4)
Utilization of foreign
  net operating loss
  carryforwards                     --            --        (1.8)
Utilization of AMT credit           --          (4.6)         --
Non-deductible expenses            2.9           9.6         2.7
Other                             (1.6)          3.1         3.7
Non-deductible write-down
  of invest. in stock               .7          37.5          --
                                  ====          ====        ====    
                                  43.0%         82.6%       37.9%
                                  ====          ====        ====    
</TABLE>

         The net  deferred  tax  asset is a result  of the  following  temporary
differences:

<TABLE>
<CAPTION>
                                                 Year Ended December 31
                                            ----------------------------------
                                               1996          1995       1994
                                            -----------   ---------   --------
<S>                                         <C>           <C>         <C>     
Comp. not currently recognized 
  for tax reporting                         $180,126      $213,100    $208,797
Allowance for bad debts                      428,761       316,090     319,834
Domestic restructuring reserve                    --            --      29,922
International restructuring reserve          196,417       188,415      46,850
Tax credits benefited                             --            --      98,500
Depreciation                                  95,067       (62,256)    (54,437)
Accrued expense                               (4,395)       19,982          --
Inventory reserve                                 --        60,955          --
Amortization expense                          37,264        22,441          --
Other                                            550         6,525      18,575
                                            ========      ========    ========
                                            $933,790      $765,252    $668,041
                                            ========      ========    ========
</TABLE>

         During 1996 and 1995,  the  Company  recorded a capital  write-down  of
$61,846  and  $529,625,  respectively,  for  which a tax  benefit  has not  been
recognized.


                                      F-11
<PAGE>
                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


(4)      Lease Obligations

         Included in property  and  equipment  at December  31, 1996 and 1995 is
laboratory and office equipment held under capitalized  leases as follows:  1996
1995.

<TABLE>
<CAPTION>
                                                    1996          1995
                                                  --------      --------
    <S>                                           <C>           <C>     
    Property and equipment                        $752,240      $731,444
    Less - accumulated depreciation                660,312       665,468
                                                  --------      --------
                                                  $ 91,928      $ 65,976
                                                  ========      ========
</TABLE>

         The future minimum lease payments under non-cancelable operating leases
and the present value of future  minimum  capital lease payments at December 31,
1996 are:

<TABLE>
<CAPTION>
                                                         Capital    Operating
                                                         Leases      Leases
                                                         -------    ---------
    <S>                                                  <C>         <C>     
    1997                                                 $29,672     $989,246
    1998                                                  33,796      800,823
    1999                                                  19,630      791,114
    2000                                                  15,768      790,455
    2001                                                   9,842      730,695
    Thereafter                                                --    1,006,931
                                                         -------   ----------
    Minimum Lease Payments                               108,708   $5,109,264
                                                                   ==========
    Less - Amount representing interest                   12,990
                                                         -------
      Present value of total minimum lease payments      $95,718
                                                         =======
</TABLE>

         Total rental expense  relating to operating  leases for the years ended
December 31, 1996,  1995, and 1994 was  approximately  $1,041,127,  $864,549 and
$793,850, respectively.

         The Company  leases office and  laboratory  space at two  facilities in
Stratford,  Connecticut  under a nine year  lease  commencing  June 1994 with an
option to renew for up to three  years and a ten month  lease  commencing  March
1997 with an option to renew for an additional  one-year period. The annual rent
on these  leases will be increased by a pro rata portion of the increase in real
estate taxes and the increase in common area maintenance.

         The Company also leases five regional sales offices located in Florida,
Maryland, North Carolina, Texas and Ohio. The terms of the leases range from one
to three years.

         In March 1996, the Company  executed a lease for a laboratory  facility
in Wilmington, Ohio with a five year term commencing April 1, 1996 and a renewal
option for five additional terms of three years each.

(5)      Stock-Based Compensation Plans

         In June 1991, the Company  adopted the 1991 Stock  Incentive Plan which
provides for up to 400,000 shares of the Company's  Common Stock, par value $.01
per share ("Common  Stock"),  to be reserved for potential  future  issuance for
stock options or awards.  This plan is the  successor to the Company's  previous
plan which  expired.  As of December 31, 1996,  9,408 shares of Common Stock are
available under the 1991 Stock Incentive Plan for future issuance.  The majority
of the  options  vest 40% on the second  year and 20% each year  thereafter  and
expire ten years from the original grant date.


                                      F-12

<PAGE>
                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

    
         In October  1996,  the  Company's  shareholders  approved the Company's
adoption of the 1996 Stock  Incentive  Plan,  which  provides  for up to 700,000
shares of Common Stock to be reserved for  potential  future  issuance for stock
options or awards.  This plan is the successor to the 1991 Stock  Incentive Plan
for which only a limited  number of shares of Common Stock remain  available for
grants.  As of December 31, 1996,  463,647  shares of Common Stock are available
under the 1996 Stock  Incentive Plan. The majority of options issued to officers
and key  employees  of the Company  vest at a rate of 40% in the second year and
20% per year  thereafter  and expire ten years from the original  date of grant.
The majority of options  issued to  directors  vest at a rate of 10% per quarter
and expire ten years from the original date of grant.

         The Company  accounts  for these plans under APB Opinion No. 25,  under
which no compensation cost has been recognized.  Had compensation cost for these
plans been determined  consistent with FASB Statement No. 123, the Company's net
income and earnings per share would have been reduced to the following pro forma
amounts:

<TABLE>
<CAPTION>
                                                           1996          1995
                                                           ----          ----
     <S>                                 <C>            <C>           <C>
     Net Income:                         As Reported    $2,170,116    $107,096
                                         Pro Forma      $1,586,169    $ 11,403
     Primary and Fully Diluted EPS:      As Reported        $.34        $.02
                                         Pro Forma          $.25        $.00
</TABLE>

         Because the Statement 123 method of accounting  has not been applied to
options  granted prior to January 1, 1995, the resulting pro forma  compensation
costs  may not be  representative  of that to be  expected  in future  years.  A
summary  of the  status of the  Company's  two fixed  stock  option  plans as of
December 31, 1996,  1995 and 1994,  and changes during the years ending on those
dates is presented below:

<TABLE>
<CAPTION>
                                                         1996                   1995                   1994
                                                        Weighted               Weighted               Weighted
                                                        Average                Average                Average
                                           1996         Exercise     1995      Exercise      1994     Exercise
Fixed Options                             Shares         Price      Shares      Price       Shares     Price
- -------------                             ------        --------    ------     --------     ------    --------
<S>                                      <C>             <C>        <C>         <C>        <C>        <C>
Outstanding at beginning
  of year                                397,153         $5.42      298,736     $5.89      261,484    $7.49
Granted                                  296,550          6.43      197,409      5.26      253,908     4.56
Exercised                                (23,621)         4.56       (4,688)     4.08      (31,665)    1.28
Forfeited                                (72,406)         5.06      (94,304)     6.78     (184,991)    7.83
                                        --------         -----     --------               --------
Outstanding at end of year               597,676          6.00      397,153      5.42      298,736     5.89
                                        --------         -----     --------               --------
Options exercisable at year-end          120,512          6.35       93,440      6.73       45,080     7.87
Weighted-average fair value of
  options granted                          $5.19                      $4.25

</TABLE>

         279,063 of the 597,676  options  outstanding  at December 31, 1996 have
exercise prices between $4.13 and $6.00,  with a weighted average exercise price
of $4.92 and a weighted average remaining  contractual life of 8.2 years. 82,277
of these options are  exercisable;  their  weighted  average  exercise  price is
$4.58.  285,013 of the 597,676 options  outstanding have exercise prices between
$6.01 and $8.00,  with a weighted average exercise price of $6.50 and a weighted
average  remaining  contractual  life of 9.8  years.  4,845 of the  options  are
exercisable;  their  weighted  average  exercise  price is $6.52.  The remaining
33,600 options have exercise  prices  between $8.01 and $10.75,  with a weighted
average  exercise price of $10.69 and a weighted average  remaining  contractual
life of 4.2 years.  33,390 of these  options  are  exercisable;  their  weighted
average exercise price is $10.69.


                                      F-13

<PAGE>

                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


         The fair value of each option  grant is  estimated on the date of grant
using the Black-Scholes option pricing model with the following weighted average
assumptions used for grants in 1996 and 1995, respectively,:  risk-free interest
rates of 6.67 and 6.78 percent;  expected  lives of 8.1 years for 1996 and 1995;
expected volatility of 80 percent for 1996 and 1995.

         In June 1994,  the  Company  offered  the  officers  and key  employees
(except  for the  Chairman  of the  Board and Chief  Executive  Officer)  of the
Company an  opportunity  to revise  the terms of their  original  stock  options
issued in 1991, 1992, and 1993.

         In June 1994,  employees who held 1991 unexercised vested non-incentive
stock options with an exercise price of $3.85 per share and termination  date of
April 23, 1995 were offered the  opportunity  to exchange  them on a one-for-one
basis for vested non-incentive stock options exercisable until April 30, 2000 at
the fair market value on June 9, 1994 of $4.56 per share. In addition, employees
who held 1991 unexercised unvested  non-incentive stock options with an exercise
price of $3.85 per share were  offered the  opportunity  to  exchange  them on a
one-for-one  basis for incentive stock options  exercisable until April 30, 2000
at the fair market value on June 9, 1994 of $4.56 per share with  vesting  terms
identical to the exchanged options.

         In June 1994,  employees who held 1991 and 1992  unexercised  incentive
stock  options with an exercise  price of $9.88 and $9.94  respectively  had two
options  available.  They were  offered the  opportunity  to exchange  them on a
five-for-four basis for incentive stock options exercisable until April 30, 2001
and 2002,  respectively,  at the fair market  value on June 9, 1994 of $4.56 per
share or  exchange  them on a  one-for-one  basis for  incentive  stock  options
exercisable  until  April  30,  2001 and  2002,  respectively,  at the  original
exercise prices of $9.88 and $9.94, respectively.

         In June  1994,  employees  who held 1993  unexercised  incentive  stock
options with an exercise price of $8.00 were offered the opportunity to exchange
them on a  five-for-four  basis for incentive  stock options  exercisable  until
April 30, 2003 at the fair market value on June 9, 1994 of $4.56 per share.

         In addition to the  disclosures  above related to options granted under
the Company's  1991 Stock  Incentive  Plan and 1996 Stock  Incentive  Plan,  the
disclosure  that  follows  relates to options  granted  pursuant  to  employment
agreements or otherwise not under such plans.

         In June 1994, the Company granted options to purchase 20,000 and 30,000
shares of Common  Stock at $4.56 per share to the  Chairman of the Board and the
Chief Executive Officer of the Company, respectively.  These options vest over a
five year period. In addition, the Chairman of the Board and the Chief Executive
Officer  were  offered the  opportunity  to amend  certain  non-qualified  stock
options of 71,282  shares each for options with  identical  exercise  prices and
vesting  provisions  and  with  expiration  dates  equal to ten  years  from the
original date of issue.  The Chief  Executive  Officer was offered an additional
opportunity to exchange the 71,282 shares of non-qualified  stock options for an
equal number of shares of incentive stock options.

         In August 1994, the Company  authorized and granted options to purchase
10,000 shares of Common Stock at $6.00 per share to one outside  Director of the
Company,  Dr.  Katopodis,  which option vests over a five-year  period.  Also in
August  1994,  the Company  authorized  the award of options to purchase  10,000
shares of Common  Stock at $6.00 per share to a second  outside  Director of the
Company, Dr. Sklar, but because of certain restrictions  applicable to Dr. Sklar
at the time of such award he was not able to accept a grant of such options.

         In January 1995, the Chief  Executive  Officer of the Company  resigned
his  employment  with the Company.  As part of the  severance  agreement,  stock
options to purchase  69,916 shares of Common Stock at prices  ranging from $4.56
to $10.75 were canceled and stock options to purchase  116,084  shares of Common
Stock were amended to set their exercise price at $5.25.  These amended  options
vested 25% in March, 1995. The remaining 75% vested in January 1997.


                                      F-14

<PAGE>
                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


         In July 1995, the Company  adopted the DIANON  Systems,  Inc.  Employee
Stock  Purchase  Plan (the "ESPP" or "Plan") as  described in Section 423 of the
Code.  The Plan provides for the sale of not more than 300,000  shares of Common
Stock,  subject to adjustments in the event of stock splits and other changes in
capitalization. The Plan provides that all shares issued pursuant to the Plan be
treasury shares acquired by the Company in open market  transactions and that no
shares issued will be authorized but unissued Common Stock. Commencing on August
15, 1995, the Company  offered the ESPP to eligible  employees as defined by the
Plan at a purchase  price equal to the lesser of 85% of the market  price at the
date of grant or 85% of the market price at the date of exercise or as otherwise
defined in the grant offering.

         In May 1996, the Company granted an officer options to purchase 200,000
shares of Common  Stock at $5.69 per share  pursuant to the terms of an employee
agreement. These options vest 40% in May 1998 and 20% over each year thereafter.

         In October 1996, the Company  granted options to purchase 10,000 shares
of Common Stock at $7.13 per share to an outside director of the Company, Mr. de
Bruin,  in  replacement  of options  issued in June  1993.  These  options  vest
immediately and expire ten years from the date of grant.

(6)      Related Parties

         The Company pays Dr.  Katopodis,  a  stockholder  who is also  Chairman
Emeritus and who was a director  until  January 1995, a royalty of 6% of revenue
on sales of  technology  covered by a license  agreement,  which was  revised in
January 1995 and has no minimums.  Pursuant to a consulting agreement revised in
March 1990, on a  month-to-month  basis, the Company provides Dr. Katopodis with
certain  insurance  benefits,  the use of an automobile and the reimbursement of
expenses incident to his performance as a consultant to the Company. The Company
paid licensing and royalty fees to this  stockholder of  approximately  $79,000,
$122,000 and $110,000  during the years ended December 31, 1996,  1995 and 1994,
respectively.

         In 1995, the Company entered into a three year research and development
agreement  with  Brigham & Women's  Hospital,  Inc. The  agreement  requires the
Company to make quarterly  payments of $30,000 totaling $360,000 in exchange for
an option to obtain rights in certain existing  inventions as well as inventions
developed during the course of the research in the areas of cancer detection and
diagnosis. The research is to be conducted by Dr. Sklar, M.D., a director of the
Company.  The Company paid $120,000 and $60,000 under this agreement in 1996 and
1995,  respectively.  As of December 31, 1996, the Company has  terminated  this
agreement  effective  as of June 30,  1997 and has  accrued  $60,000  for future
payments  in 1997.  In  addition,  the  Company  has made  payments to Brigham &
Women's  Hospital,  Inc.  of  $30,000  in each of 1995 and  1996 for  consulting
services by Dr. Sklar.

         For description of a loan from the Company to Mr. Johnson,  see Item 11
- - Executive Compensation - "Employment and Severance Agreements".

         In January 1997,  the Company  purchased  89,000 shares of Common Stock
from Richard A. Sandberg at a price of $8.50 per share.

         See also Note 14.

(7)      Restructuring Costs

         In  1995,  the  Company  provided  for a  reserve  of  $279,000  due to
management's  decision  to  discontinue  European  based  operations.  Remaining
reserves  for  the  discontinuance  of  operations  at  December  31,  1996  are
approximately  $155,000.  The  Company  is in the  process  of  liquidating  the
European based  operations and plans to complete the liquidation  process by the
end of the 1997 fiscal year.


                                      F-15
<PAGE>
                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


(8)      Commitments

         The Company is involved in certain  legal  matters  which  periodically
arise in the normal course of business.  Management believes that the outcome of
these legal  matters will not have a material  adverse  effect on the  financial
position and results of operations of the Company.

(9)      Employee Benefit Plan

         The Company  established  a 401(k)  employee  benefit plan  pursuant to
which   participants   receive  certain  benefits  upon  retirement,   death  or
termination of employment.  The Company is required to contribute  amounts equal
to 20% of the  contributions  made by  employees  up to 1% of their total annual
salary  (subject  to tax code  limits).  The Company  contributed  approximately
$88,000,   $67,000  and  $44,000  to  the  plan  during  1996,  1995  and  1994,
respectively.   The  Company  offers  no  other   post-retirement   benefits  or
post-employment benefits to its employees.

(10)     Investment in Common Stock and Warrants

         During 1996, the Company  recorded  charges of $62,000 to write-off the
investment in common stock of a publicly traded company as the loss in value was
deemed other than temporary in accordance with Statement of Financial Accounting
Standard  115,   "Accounting   for  Certain   Investments  in  Debt  and  Equity
Securities".  During  1995,  a  similar  charge  of  $530,000  was  recorded  to
write-down  the  investment  to  market  value.  The  Company  plans to sell its
remaining 24,386 shares of common stock of such company in 1997.

(11)     Note Payable

         In July 1993, the Company  obtained a $3,500,000  term loan from a bank
that bears  interest  at 6% per year.  This term loan and  accrued  interest  is
repayable in 47 monthly installments of approximately $82,000 which commenced in
September  1993 plus one final  payment in August  1997  equal to the  remaining
unpaid principal and interest.  The term loan requires the Company to maintain a
$2 million compensating balance as well as certain financial ratios or financial
results  related to tangible  net worth,  debt service  coverage,  indebtedness,
working  capital and current  ratio.  The  Company  was in  compliance  with all
covenants  as of  December  31,  1996.  The fair  market  value of this  note is
determined using discounted cash flows based on the Company's  estimated current
interest  rate for similar  types of  borrowings.  As of December 31, 1996,  the
carrying value of the note payable approximates its fair market value.

(12)     Rights Agreement

         On April 29,  1994,  the Board of  Directors  of DIANON  Systems,  Inc.
declared  a dividend  distribution  of one Right for each  outstanding  share of
Common Stock, par value $.01 per share, of the Company to stockholders of record
on May 10, 1994. Each Right entitles the registered  holder to purchase from the
Company a unit ("Unit")  consisting of one  one-hundredth of a share of Series A
Junior Participating  Preferred Stock, par value $.01 per share, of the Company,
at a price of $20 per Unit, subject to adjustment, upon change of control in the
Company, as defined in the rights agreement`.

(13)     Severance Costs

         During 1996, the Company recorded a reserve of  approximately  $148,000
for severance  costs as a result of the  resignation of certain  officers of the
Company,  of which  approximately  $61,000 was paid during 1996.  All  remaining
severance is expected to be paid by the end of the second quarter of 1997.

         During 1995, the Company recorded a reserve of  approximately  $595,000
for severance costs as a result of streamlining its operating  expenses and with
respect to the resignation of certain  officers of the Company.  These severance
costs were paid by the end of the second quarter of 1996.



                                      F-16

<PAGE>

                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


(14)     Private Placement

         On  October  5,  1995,  the  Company  completed  a  $5,612,000  private
placement with an investor for one million shares of Common Stock and a two-year
warrant  for  800,000  shares  exercisable  at $6.00 per  share of Common  Stock
(except as otherwise  described below).  The Company received cash of $5,316,000
and a two-year promissory note for $296,000 bearing 7% interest.  Some or all of
the  warrants  could be  exercised  at a price of $5.00 at any time on or before
October 31, 1996. Upon such election the Company would be required to extinguish
as an adjustment  to the purchase  price paid for such  warrants,  for each such
warrant for which such election has been made,  $0.37 of the principal amount of
the note upon payment of the interest  due on such  extinguished  amount for the
outstanding  period. If the warrants for 800,000 shares were all exercised on or
before  October 31, 1996,  the two year  promissory  note for $296,000  would be
fully  extinguished.  On August  20,  1996,  the  Company's  Board of  Directors
approved an  amendment  to the terms of the  warrants to extend from  October 4,
1996 to October 31, 1996, the date through which the warrants could be exercised
at $5.00 per share. The amendment was approved in connection with the scheduling
of the  Company's  Annual  Meeting for October 24, 1996 to enable voting at such
meeting on the Company's  agreement to enable the investor to vote shares of the
Company's   common  stock  owned  by  such   investor  and  certain   affiliates
representing  up to  20% of the  total  voting  power  of the  Company's  voting
securities outstanding from time to time to be completed prior to the expiration
of the $5.00 per share exercise price.  The Company's  agreement was approved at
the  Company's  Annual  Meeting on October 24, 1996.  On October 29,  1996,  the
investor  exercised  warrants  for all 800,000  shares and in  exchange  for the
payment  of  approximately  $4.0  million  in cash  representing  the  aggregate
exercise  price of such  warrants  and interest on the  principal  amount of the
two-year  promissory note for the outstanding  period, the Company issued to the
investor 800,000 shares of its Common Stock and fully extinguished and cancelled
the promissory note.
































                                     F-17

<PAGE>


                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To DIANON Systems, Inc.:

         We  have  audited  in  accordance  with  generally   accepted  auditing
standards,  the consolidated  financial  statements of DIANON Systems,  Inc. and
subsidiary  companies  included  in this Form 10-K and have  issued  our  report
thereon dated February 27, 1997. Our audits were made for the purpose of forming
an opinion on the basic consolidated  financial statements taken as a whole. The
schedule  listed  in the  index  to  consolidated  financial  statements  is the
responsibility  of the  Company's  management  and is presented  for purposes of
complying with the Securities and Exchange Commission's rules and is not part of
the basic consolidated financial statements. This schedule has been subjected to
the  auditing  procedures  applied  in  the  audits  of the  basic  consolidated
financial statements and, in our opinion, fairly states in all material respects
the  financial  data  required to be set forth  therein in relation to the basic
consolidated financial statements taken as a whole.

                               ARTHUR ANDERSEN LLP

Stamford, Connecticut
February 27, 1997












































                                   F-18

<PAGE>


                              DIANON SYSTEMS, INC.
                SCHEDULE II -- VALUATION AND QUALIFYING ACCOUNTS

<TABLE>
<CAPTION>
                                               Balance at  Provision
                                               Beginning      for      Charges to  Balance at
                                                of Year    Allowance   Allowance   End of Year
                                               ---------   ---------   ----------  -----------
<S>                                            <C>         <C>         <C>         <C>       
For the year ended December 31, 1994
    Allowance for bad debts                    $670,230    $839,200    $774,180    $  735,250
    Domestic restructuring reserve              550,000          --     512,252        37,748
    International restructuring reserve         174,759          --     112,057        62,702
    Severance costs                                  --     149,631      45,231       104,400
For the year ended December 31, 1995
    Allowance for bad debts                     735,250      51,670          --       786,920
    Domestic restructuring reserve               37,748          --      33,191         4,557
    International restructuring reserve          62,702     118,000      18,661       162,041
    Severance costs                             104,400     594,708     510,935       188,173
    Non-deductible write-down of investment
         in stock                                    --     529,625          --       529,625
For the year ended December 31, 1996
    Allowance for bad debts                     786,920     270,000          --     1,056,920
    Domestic restructuring reserve                4,557          --       4,557            --
    International restructuring reserve         162,041          --       6,566       155,475
    Severance costs                             188,173     147,536     248,817        86,892
    Non-deductible write-down of investment
         in stock                               529,625          --     529,625            --
</TABLE>


































                                      F-19
<PAGE>

                                  EXHIBIT INDEX

<TABLE>
<CAPTION>

EXHIBIT     
  NO.    DOCUMENT REFERENCE                                                          PAGE
- -------  ------------------                                                          ----

<S>      <C>                                                                         <C>
3.1      Restated  Certificate  of  Incorporation  of the  Company,  as  amended
         through June 12, 1991  (incorporated by reference to Exhibit 3.1 of the
         Registrant's Registration Statement No. 33-41226).

3.2      Restated  By-Laws of the Company,  as amended  through October 24, 1996
         (incorporated   by  reference  to  Exhibit  4.2  of  the   Registrant's
         Registration Statement No. 333-18817).

10.1     Consulting  Agreement,  dated August 4, 1989,  between DIANON  Systems,
         Inc. and Nonda Katopodis  (incorporated by reference to Exhibit 10.7 of
         the Registrant's Registration Statement No. 33-41226).**

10.2     Executive Vesting Agreement,  dated as of June 11, 1991, between DIANON
         Systems,  Inc.  and James B.  Amberson  (incorporated  by  reference to
         Exhibit   10.13  of  the   Registrant's   Registration   Statement  No.
         33-41226).**

10.3     1991 Stock Incentive Plan  (incorporated  by reference to Exhibit 10.17
         of the Registrant's Registration Statement No. 33-41226).**

10.4     Management  Incentive Plan  (incorporated by reference to Exhibit 10.18
         of the Registrant's Registration Statement No. 33-41226).**

10.5     Stock  Option  Grant to  Walter O.  Fredericks,  dated  April 27,  1990
         (incorporated  by  reference  to  Exhibit  10.23  of  the  Registrant's
         Registration Statement No. 33-41226).**

10.6     Stock  Option  Grant to  Richard  A.  Sandberg,  dated  June  12,  1991
         (incorporated  by  reference  to  Exhibit  10.24  of  the  Registrant's
         Registration Statement No. 33-41226).**

10.7     Stock  Option  Grant to  Richard  A.  Sandberg,  dated  June  12,  1991
         (incorporated  by  reference  to  Exhibit  10.25  of  the  Registrant's
         Registration Statement No. 33-41226).**

10.8     Lease Agreement, made as of February 14, 1989, between Watson Boulevard
         Development Limited Partnership,  as lessor, and DIANON Systems,  Inc.,
         as lessee,  for premises located at 200 Watson Boulevard  (incorporated
         by  reference  to  Exhibit  10.29  of  the  Registrant's   Registration
         Statement No. 33-41226).

10.9     License  Agreement,   dated  June  9,  1983,  between   Sloan-Kettering
         Institute for Cancer Research and N-K Laboratories  Limited Partnership
         (incorporated  by  reference  to  Exhibit  10.30  of  the  Registrant's
         Registration Statement No. 33-41226).

10.10    License Agreement, dated July 29, 1987, between University of Rochester
         and DIANON Systems, Inc. (incorporated by reference to Exhibit 10.32 of
         the Registrant's Registration Statement No. 33-41226).

10.11    Development   Agreement,   effective   September   25,  1987,   between
         Connecticut  Product Development  Corporation and DIANON Systems,  Inc.
         (incorporated  by  reference  to  Exhibit  10.33  of  the  Registrant's
         Registration Statement No. 33-41226).
</TABLE>


<PAGE>

<TABLE>
<CAPTION>

EXHIBIT     
  NO.    DOCUMENT REFERENCE                                                          PAGE
- -------  ------------------                                                          ----

<S>      <C>                                                                         <C>
10.12    Stock  Option  Grant  to  James  B.  Amberson,  dated  April  23,  1991
         (incorporated   by  reference  to  Exhibit  28.1  to  the  Registrant's
         Quarterly  Report  on Form 10-Q for the  quarter  ended  September  30,
         1991).**

10.13    Stock Option  Grant to Richard A.  Sandberg,  dated June 12,  1991,  as
         amended (incorporated by reference to Exhibit 10.37 to the Registrant's
         Annual Report on Form 10-K for the year ended December 31, 1991).**

10.14    Asset  Purchase  Agreement,  dated  April  30,  1993,  by and among the
         Registrant  and  Molecular   Oncology,   Inc.,   and  Oncologix,   Inc.
         (incorporated by reference to Exhibit 1.1 to the Registrant's  Form 8-K
         dated April 30, 1993, filed with the Securities and Exchange Commission
         on May 14, 1993).

10.15    Asset  Purchase  Agreement,  dated  June 29,  1993,  by and  among  the
         Registrant and Collaborative  Research, Inc. (incorporated by reference
         to Exhibit 1.2 to the Registrant's  Form 8-K dated June 29, 1993, filed
         with the Securities and Exchange Commission on July 13, 1993).

10.16    Term Loan  Agreement,  dated July 14, 1993, by and among the Registrant
         and the Union Trust Company (incorporated by reference to Exhibit 10.34
         to the  Registrant's  Annual Report on Form 10-K/A  Amendment 1 for the
         year ended  December 31, 1993,  filed with the  Securities and Exchange
         Commission on April 28, 1994).

10.17    Rights Agreement, dated April 29, 1994, by and among the Registrant and
         American  Stock and Trust  Company,  as Rights Agent  (incorporated  by
         reference  to Exhibit 1 to the  Registrant's  Form 8-K dated  April 29,
         1994,  filed with the  Securities  and  Exchange  Commission  on May 9,
         1994).

10.18    Severance  Agreement,   dated  January  20,  1995,  by  and  among  the
         Registrant  and John P. Davis  (incorporated  by  reference  to Exhibit
         10.36 to the Registrant's Annual Report on Form 10-K for the year ended
         December 31, 1995, filed with the Securities and Exchange Commission on
         March 29, 1996).**

10.19    Employment Agreement, dated May 3, 1996, by the Registrant and Kevin C.
         Johnson (incorporated by reference to Exhibit 10.37 to the Registrant's
         Quarterly Report on Form 10-Q for the quarter ended June 30, 1996).**

10.20    Executive  Employment  Agreement,  dated  September  1,  1996,  by  the
         Registrant  and  Richard A.  Sandberg  (incorporated  by  reference  to
         Exhibit 10.38 to the Registrant's Quarterly Report on Form 10-Q for the
         quarter ended September 30, 1996).**

10.21    Employment  Agreement,  dated  September 1, 1996, by the Registrant and
         Dr. James B.  Amberson  (incorporated  by reference to Exhibit 10.39 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         September 30, 1996).**

10.22    Executive  Employment  Agreement,  dated  September  1,  1996,  by  the
         Registrant  and Dr.  James B.  Amberson  (incorporated  by reference to
         Exhibit 10.40 to the Registrant's Quarterly Report on Form 10-Q for the
         quarter ended September 30, 1996).**

10.23    Severance  Agreement,  dated  September 27, 1996, by the Registrant and
         Carl R. Iberger  (incorporated  by  reference  to Exhibit  10.41 to the
         Registrant's  Quarterly  Report  on Form  10-Q  for the  quarter  ended
         September 30, 1996).**


</TABLE>

<PAGE>

<TABLE>
<CAPTION>

EXHIBIT     
  NO.    DOCUMENT REFERENCE                                                          PAGE
- -------  ------------------                                                          ----

<S>      <C>                                                                         <C>
10.24    Employment  Agreement,  dated September 30,1996,  by the Registrant and
         David R. Schreiber  (incorporated  by reference to Exhibit 10.42 to the
         Registrant's  Quarterly  Report  on Form  10-Q  for the  quarter  ended
         September 30, 1996).**

10.25    Employment  Agreement,  dated  November 18, 1996, by the Registrant and
         Steven T. Clayton (filed herewith).**                                        58

10.26    Severance  Agreement  dated  November 18, 1996, by the  Registrant  and
         Daniel J. Cronin, III (filed herewith).**                                    66

10.27    Amendment  dated as of October 4, 1995 to Rights  Agreement dated as of
         April 29, 1994 between the  Registrant  and American Stock Transfer and
         Trust Company,  as Rights Agent  (incorporated  by reference to Exhibit
         No. 1 to the  Registrant's  Form 8-K dated  October 30, 1996 filed with
         the Securities and Exchange Commission on November 8, 1995).

10.28    1996 Stock Incentive Plan  (incorporated  by reference to Appendix A to
         the  Registrant's  Statement on Schedule 14A filed with the  Securities
         and Exchange Commission on September 23, 1996).**

10.29    Stock and  Warrant  Purchase  Agreement,  dated as of  October 4, 1995,
         among the  Gilbert  Family  Trust,  the G.S.  Beckwith  Gilbert  I.R.A.
         Contributory  Account,  G.S. Beckwith Gilbert and the Registrant (filed
         herewith).                                                                   68

10.30    Registration  Rights Agreement,  dated as of October 4, 1995, among the
         Gilbert Family Trust,  the G.S.  Beckwith  Gilbert I.R.A.  Contributory
         Account, G.S. Beckwith Gilbert and the Registrant (filed herewith).          87

10.31    Warrant No. 1, dated as of October 4, 1995, by the  Registrant in favor
         of G.S. Beckwith Gilbert (filed herewith).                                   99

10.32    Promissory  Note,  dated October 4, 1995, by G.S.  Beckwith  Gilbert in
         favor of the Registrant (filed herewith).                                   109

10.33    Stock Option Grant dated October 24, 1996 by the Registrant to Andre de
         Bruin (filed herewith).**                                                   111

10.34    Stock Option Grant dated  November 4, 1996 by the Registrant to Jeffrey
         M. Sklar, M.D. (filed herewith).**                                          114

10.35    Loan  Agreement  dated  December 3, 1996 by the  Registrant to Kevin C.
         Johnson (filed herewith).**                                                 117

10.36    Form of  standard  Stock  Option  Grant for  outside  directors  (filed
         herewith).**                                                                120

10.37    Amendment  to Warrant  Certificate  No. W-1 dated as of October 2, 1996
         between the Registrant and G.S. Beckwith Gilbert (filed herewith).          123

10.38    Severance  Agreement,  dated  February 27, 1997, by the  Registrant and
         Richard A. Sandberg (filed herewith).**                                     125

</TABLE>


<PAGE>

<TABLE>
<CAPTION>

EXHIBIT     
  NO.    DOCUMENT REFERENCE                                                          PAGE
- -------  ------------------                                                          ----

<S>      <C>                                                                         <C>
11.1     Statement re: computation of per share earnings. *

22.1     List of  Subsidiaries  of the Company  (incorporated  by  reference  to
         Exhibit 22.1 of the Registrant's Registration Statement No. 33-41226).

23.1     1996  Consent of Arthur  Andersen  LLP  (incorporated  by  reference to
         Exhibit  23.1 of the  Registrant's  Annual  Report on Form 10-K for the
         year ended December 31, 1995).

23.2     1997 Consent of Arthur Andersen LLP (filed herewith).                       132

27.1     Financial Data Schedule.

<FN>
- --------------
*      Not applicable or contained elsewhere herein.
 
**     A management contract or compensatory plan or arrangement  required to be
       filed as an exhibit to this form pursuant to Item 14(c) of this report.
</FN>
</TABLE>


                                                                   Exhibit 10.25

                              EMPLOYMENT AGREEMENT

         This AGREEMENT made effective November 18, 1996 between DIANON SYSTEMS,
INC., a Connecticut corporation, and any successor thereto, hereinafter referred
to as the "Company," and STEVEN CLAYTON, residing in Naperville, Illinois.

                                   WITNESSETH:

         WHEREAS,  the Company wishes to employ STEVEN CLAYTON as Vice President
Information  Services of the Company  and STEVEN  CLAYTON  wishes to accept such
employment,  in each case on the terms and subject to the  conditions  set forth
below; and

         WHEREAS,  the services that STEVEN CLAYTON  should render  hereunder to
the Company are unique and valuable; and

         WHEREAS,  the  parties  desire to reduce  the terms and  conditions  of
STEVEN CLAYTON's employment to writing;

         NOW,  THEREFORE,  in  consideration of the terms and conditions and the
mutual  covenants  contained in this  Agreement,  the Company and STEVEN CLAYTON
hereby agree as follows:

         1.       Employment

         The Company  hereby  employs  STEVEN  CLAYTON and STEVEN CLAYTON hereby
accepts such employment upon the terms and conditions hereinafter set forth. The
parties acknowledge that STEVEN CLAYTON's employment with the Company is at will
and terminable by either party at any time for any reason.

         2.       Duties and Responsibilities

         STEVEN CLAYTON shall perform with continuous diligence those activities
assigned to STEVEN CLAYTON by the Company's  Senior Vice  President  Finance and
Chief Financial Officer,  President and Chief Operating Officer, Chief Executive
Officer  and/or  Board  of  Directors  from  time to time,  initially  including
responsibility  for Information  Services;  keeping full and complete records of
all business  and/or  research  activities in which STEVEN  CLAYTON  engages and
surrendering all such records and materials on request; improving strategies for
achieving the Company's goals; motivating co-worker performance; keeping abreast
of all new  developments  in STEVEN  CLAYTON's area of expertise;  participating
actively in research and business meetings; and abiding by all Company policies.

         3.       Salary and Incentive Compensation

         The Company shall compensate STEVEN CLAYTON for his services during the
term of this  Agreement  on a  salaried  basis  paid in  installments  at a rate
determined  by the Company  from time to time,  provided  that the initial  base
salary shall be at an  annualized  rate of $120,000.  STEVEN  CLAYTON shall also
participate,  according to its terms, in any management  incentive  compensation
program maintained by the Company for salaried Grade 17 management  employees of
the Company during the term of this Agreement.

         4.       Relocation, Travel Expenses and Temporary Housing

         The  Company  shall  provide  STEVEN  CLAYTON  relocation  expenses  in
accordance  with  the  terms  of  its  established  relocation  policy  for  his
relocation from Illinois to Connecticut in connection  with the  commencement of
his employment with the Company. The Company shall pay STEVEN CLAYTON reasonable
costs associated with temporary  housing,  including car rental, for up to three
months in connection with such  relocation.  The Company shall also pay air fare
for up to twelve round-trips  between Connecticut and Chicago in connection with
such relocation.


<PAGE>

         5.       Signing Bonus

         The Company  shall pay STEVEN  CLAYTON a signing  bonus of $14,000 less
applicable  tax  deductions  within a  reasonable  time after he  commences  his
employment with the Company.

         6.       Fringe Benefits

         During the term of this  Agreement,  the Company shall  provide  STEVEN
CLAYTON  benefits and  emoluments as authorized  for all other salaried Grade 17
management employees of the Company as they may be modified from time to time by
the  Company  during  the  term  of this  Agreement,  including  at the  time of
execution of this Agreement,  health and medical insurance, life insurance, sick
leave, vacation, holidays, retirement plan participation and stock purchase plan
participation..

         7.       Stock Options

         On the first day of  STEVEN  CLAYTON's  active  employment  under  this
Agreement,  the Company  shall award him  options to purchase  15,000  shares of
common  stock of the Company at the fair market  value on said date,  subject to
the terms,  conditions,  vesting schedules and expiration dates described in the
incentive stock option award document attached to this Agreement as Exhibit A.

         8.       Company Property

         At the  time his  employment  with the  Company  terminates,  or at any
earlier  point in time when a request is made by the  Company  for same,  STEVEN
CLAYTON  will turn over to the Company  all notes,  reports,  memoranda,  books,
records,  chemicals,  devices and  documents,  whether in written,  typewritten,
computerized  or any other form,  which are in STEVEN  CLAYTON's  possession  or
under his control,  whether prepared by him or others, related to the Company or
relating to the business of the Company.

         9.       Proprietary Information

         STEVEN  CLAYTON  hereby  agrees to all the terms and  conditions of the
Company's Employee Proprietary  Information Agreement attached hereto as Exhibit
B and incorporated herein and has executed a copy thereof concurrently with this
Agreement.

         10.      Non Competition

         STEVEN CLAYTON agrees that, to the fullest extent permitted by law, for
the period of one (1) year after his  termination  date STEVEN  CLAYTON (a) will
not solicit business on behalf of any entity in the clinical chemistry business,
which is  performing  or marketing  anatomical  pathology  services  ("Competing
Entity"),  (b) will not solicit business from customers of the Company, (c) will
not solicit the  employment  or services of any of the  employees of the Company
and  (d)  will  not,  directly  or  indirectly,  participate  in the  ownership,
management,  operation  or control of any  Competing  Entity in the  continental
United  States  other than  California,  Washington  and Oregon,  provided  that
nothing in this Paragraph shall prevent investment  ownership of less than 5% of
the shares of any publicly traded Competing Entity.

         11.      Remedy for Breach

         STEVEN CLAYTON acknowledges:

                  (a)      that he may be a director  and officer of the Company
                           and as such he would  be  conversant  with,  and have
                           access  to,  the  business  affairs,  records,  trade
                           secrets,  customers  and customer  lists,  suppliers,
                           supplier   lists,   patents,    technical   know-how,
                           chemicals,  devices, sales or distribution agents and
                           representatives,  sales or  distribution  agents  and
                           representatives'  lists,  and other  confidential and
                           proprietary information of the Company;


<PAGE>

                  (b)      that his compliance with the covenants and agreements
                           in  this   Agreement  is  necessary  to  protect  the
                           goodwill  and  other  proprietary   interest  of  the
                           Company; and

                  (c)      that a breach of his covenants and agreements in this
                           Agreement will result in continuing  and  irreparable
                           damage  to the  Company  for which  there  will be no
                           adequate remedy at law.

         Both the parties  recognize that the services to be rendered under this
Agreement  by STEVEN  CLAYTON  are  special  and unique and of an  extraordinary
character,  and that in the event  there is a breach by  STEVEN  CLAYTON  of the
terms and  conditions of this Agreement to be performed by him, then the Company
shall be entitled,  if it so elects,  to institute and prosecute  proceedings in
any  court of  competent  jurisdiction  either  in law or in  equity,  to obtain
damages for any breach of this Agreement, or to enforce the specific performance
thereof by STEVEN CLAYTON,  or to enjoin STEVEN CLAYTON from performing services
for any Competing Entity.

         12.      STEVEN CLAYTON'S Representation

         STEVEN CLAYTON  warrants and represents  that neither the execution and
delivery nor the  performance  of this Agreement by him will in any way violate,
or conflict  with,  any other  agreement by which he may be bound or any duty or
obligation to which he may be subject and that he will take all steps  necessary
to comply with the representation.

         13.      Assignments

         The rights and obligations of STEVEN CLAYTON under this Agreement shall
be  assignable  to and binding  upon the  successors  and assigns of the Company
including any  corporation  organized by the Company to carry on the business of
the Company.

         14.      Entire Agreement

         This instrument  contains the entire  Agreement of the parties.  It may
not be changed  orally,  but only by  agreement  in writing  signed by the party
against  whom  enforcement  of any waiver,  change,  modification,  extension or
discharge is sought.  This  Agreement  supersedes  any verbal,  written or other
agreement(s) or understanding(s) existing between STEVEN CLAYTON and the Company
relating to his employment or the other matters covered herein.

         15.      Severability

         If any  provision  of  this  Agreement  shall  be  held  invalid,  such
invalidity  shall not affect any other  provisions of this Agreement not held so
invalid,  and only such provisions shall to the full extent  consistent with the
law remain in full force and effect.


<PAGE>

         16.      Applicable Law

         This  Agreement  shall  be  governed  by  the  laws  of  the  State  of
Connecticut.

         IN WITNESS WHEREOF,  the parties have executed or caused to be executed
this Agreement.


                                    DIANON   SYSTEMS INC.



12/8/96                             BY: /s/David R. Schreiber
- -------------------                     --------------------------------
Date                                    David R. Schreiber
                                        Chief Financial Officer and
                                        Senior Vice President, Finance




12/11/96                            BY: /s/Steven Clayton
- -------------------                     --------------------------------
Date                                    Steven Clayton



<PAGE>

                                                                       Exhibit A

                              DIANON SYSTEMS, INC.
                              200 Watson Boulevard
                          Stratford, Connecticut 06497

                                                        SO Grant No.

                               STOCK OPTION GRANT


Optionee:                     Steve Clayton    Date of Grant:  November 18, 1996

Termination Date:         November 17, 2006    Total No. of Shares:       15,000

Exercise Price Per Share             $7.875


We are  pleased to inform you that the  Compensation  Committee  of the Board of
Directors of DIANON  Systems,  Inc.  (the  "Company"),  has today granted you an
option  pursuant to the  Company's  1991 Stock  Incentive  Plan (the  "Plan") to
purchase an  aggregate  number of shares  shown above of the Common Stock of the
Company on the following terms and conditions:

         1. The purchase  price per share of the shares of Common Stock  subject
to this option is $6.625 per share.

         2. This option  shall  expire at the close of business on November  17,
2006. Subject to acceleration in the event of a Change of Control (as defined in
the Plan), you must remain in the employ of the Company or a Related Company (as
defined in the Plan) for two years from the date hereof  before you can exercise
any part of this  option.  Thereafter  this option will  become  exercisable  in
installments as follows:

<TABLE>
<CAPTION>
          Percentage of Shares              Date of Earliest Exercise(Vesting)
          --------------------              ----------------------------------

                  <S>                                       <C>
                  40%                                       11/18/98
                  20%                                       11/18/99
                  20%                                       11/18/00
                  20%                                       11/18/01
</TABLE>

         In the event of a Change of Control  this  option  shall  become  fully
exercisable and vested.

         3. This option is intended to qualify as an  "Incentive  Stock  Option"
within the provisions of Section 422 of the Internal Revenue Code.

         4. The option  price shall be payable by you at the time this option is
exercised,  (i) in cash or (ii) by  delivering  shares  of  Common  Stock of the
Company which you have owned for at least six months prior to such exercise,  or
a combination  of cash and such shares,  having an aggregate  value equal to the
aggregate  option  price of the  shares as to which  this  option  is  exercised
(basing the value of any such shares of Common Stock on the fair market value of
the Common  Stock on the date of  exercise).  No shares of Common Stock shall be
issued pursuant to exercise of this option until full payment  therefor has been
made.

         5. This option may be exercised  only by you and may not be transferred
except by will or the laws of  descent  and  distribution.  In the event of your
death, your legal  representatives  may exercise this option as to the shares of
Common  Stock which were  immediately  purchasable  by you at the date of death,
within ninety (90) days  following the date of death (but in no event later than
November 17, 2006).


<PAGE>

         6. If your employment with the Company  terminates  after reaching your
normal  retirement  date under the Company's  retirement  plan or for any reason
beyond your  control  other than your death,  your  option  privileges  shall be
limited to the shares of Common Stock which were immediately  purchasable by you
at the date of such  termination and such option  privileges shall expire unless
exercised  within ninety (90 days) days after the date of such  termination  and
prior to the close of business on  November  17,  2006.  If your  employment  is
terminated for reasons within your control, including without limitation,  cause
and voluntary resignation, all rights under this option shall expire on the date
of such termination.

         7. Your option is granted in tandem with a Limited  Stock  Appreciation
Right ("LSAR") which may be exercised only within the 60-day period  following a
Change of Control (as defined in the Plan). This means that with respect to each
share under  option,  you may  exercise  either the option or the Limited  Stock
Appreciation   Right,   but  not  both.  Upon  exercise  of  the  Limited  Stock
Appreciation Right, you shall receive,  for each share with respect to which the
Limited Stock Appreciation  Right is exercised,  an amount equal in value to (I)
the fair market  value of a share of Common  Stock on the date of exercise  over
(ii) the exercise price of the related  option.  The Limited Stock  Appreciation
Right shall be payable solely in cash.  Such amount shall be paid within 30 days
of the exercise of the Limited Stock Appreciation Right.

         8. The  Company  has the right to delay the  exercise of your option if
listing  registration or qualification of the Common Stock is required under any
federal or state  securities  law or stock  exchange or similar rule and has not
been obtained.

         9.  Nothing  herein  shall  restrict  the right of the  Company  or any
Related Company to terminate your employment at any time, with or without cause,
or to withhold  required  amounts upon the exercise of your option or LSAR.  The
Company  shall have the right to require you to pay, or make other  arrangements
satisfactory  to the Committee to satisfy,  all tax  withholding  obligations in
connection with the exercise of your option or LSAR.

         10. This option is subject to all of the other  terms,  provisions  and
conditions  of the  Plan,  a copy of which has been  furnished  to you and other
copies of which may be obtained by you from the Company.

                                              Very truly yours,

                                              DIANON Systems, Inc.



                                              By:   /s/Kevin C. Johnson
                                                  -------------------------
                                                    Kevin C. Johnson
                                                    President



Date:        12/11/96
     -------------------------

     /s/Steven Clayton
- ------------------------------
(Signature)

     1439 Keats Ave.
- ------------------------------
(Address)

      Naperville, IL  60564
- ------------------------------


<PAGE>

                                                                       Exhibit B

                                    AGREEMENT

         THIS AGREEMENT, made this 12/11/96 by and between DIANON SYSTEMS, INC.,
its  affiliates,  subsidiaries,  successors  and  assigns  (collectively  called
hereinafter  "DIANON") and Steven Clayton,  an individual residing at 1439 Keats
Avenue, Naperville, Illinois 60564 (hereinafter called "Employee").

         In  consideration  of the  commencement  of Employee's  employment with
DIANON, the payment of compensation and benefits for such employment, and access
to sensitive information,  Employee and DIANON acknowledge,  represent and agree
to the terms and conditions set forth in this Agreement.

         1.  Employee's  employment  with DIANON creates a relationship of trust
and  confidence  between the parties.  Employee  agrees  that,  during and after
his/her  employment  with DIANON,  Employee  will not use or disclose,  or allow
anyone else to use or disclose,  any  confidential  information  relating to the
products, sales and/or business affairs of DIANON or of any customer or supplier
of DIANON,  or any  information  created,  discovered,  or  developed  by or for
DIANON, or acquired by DIANON,  that has commercial value in DIANON's present or
future business ("Confidential Information"),  except as may be necessary in the
performance  of  Employee's  employment  with DIANON or as may be  authorized in
advance by  appropriate  officials of DIANON.  By way of  illustration,  but not
limitation,   Confidential  Information  includes  processes,   formulas,  data,
know-how, inventions,  improvements,  techniques, marketing plans, product plan,
strategies,  forecasts,  customer lists and any other  information  Employee has
reason to know  DIANON  would  like to treat as  confidential  for any  purpose.
Employee  agrees to keep  Confidential  Information  secret  whether  or not any
document containing such information is marked confidential.

         2. All rights, title and interest in all records,  documents,  or files
concerning the business of DIANON,  including,  but not limited to biomaterials,
processes,  letters,  trade  secrets,  laboratory  notebooks or other written or
electronically recorded material, whether or not produced by the Employee, shall
be and remain the  property  of DIANON.  Upon  termination  of  employment,  the
Employee shall not have the right to remove any such records from the offices of
DIANON. In addition,  Employee agrees to promptly return to DIANON all things of
whatsoever  nature that belong to DIANON,  and all records (in whatsoever  form,
format or medium) contained or related to Confidential Information of DIANON.

         3. Employee agrees to assign,  and does hereby assign to DIANON, all of
his/her  right,  title  and  interest  in and to all  inventions,  improvements,
discoveries or technical developments,  whether or not patentable,  which he/she
solely or jointly  with others,  may  conceive or reduce to practice  during the
term of his/her  employment (a) which are related in whole or in part,  directly
or indirectly,  to DIANON's product line, research and development,  or field of
technological or industrial specialization,  or (b) in the course of utilization
by DIANON of Employee's services in a technical or professional  capacity in the
areas  of  research,   development,   marketing,   management,   engineering  or
manufacturing,  or (c)  pursuant  to any  project of which  Employee is or was a
participant or member that is or was either  financed or directed by DIANON,  or
(d) at DIANON's expense, in whole or in part.

         4. Employee  agrees to disclose  promptly to DIANON's  President or his
designee, all ideas,  discoveries,  and improvements conceived by Employee alone
or in collaboration with others, and to cooperate fully with DIANON, both during
and after  employment,  with  respect  to the  procurement  of  patents  for the
establishment and maintenance of DIANON's or its designee's rights and interests
in said invention,  improvement,  discoveries or  developments,  and to sign all
papers which DIANON may deem  necessary or desirable  for the purpose of vesting
DIANON or its  designees  with such rights,  the expenses  thereof to be paid by
DIANON.

         5. The Employee  shall,  while employed by DIANON,  devote his/her best
efforts and his/her full time to the business of DIANON.


<PAGE>

         6. In the event of a breach or threatened  breach of the  provisions in
this  Agreement,  DIANON  shall be entitled to an  injunction  restraining  such
breach,  it being  recognized  that any injury  arising  from a breach  would be
irreparable  and could have no adequate  remedy at law; but nothing herein shall
be construed as prohibiting  DIANON from pursuing any other remedy available for
such  breach or  threatened  breach.  In the event  that  Employee  breaches  or
threatens  a breach of this  Agreement,  DIANON  shall be  entitled  to have its
reasonable  legal fees and costs  paid by the  Employee  for any legal  services
relating to the breach or threatened breach.

         7. This  Agreement is not intended,  and should not be construed in any
way, as a contract of  employment  for a definite  period of time or to limit or
restrain   DIANON's  or  the  Employee's   right  to  terminate  the  employment
relationship at any time.

         8. In the  event  any  provision  or  paragraph  of this  Agreement  is
declared to be invalid or unenfoceable, then the balance of this Agreement shall
remain in full force and effect.

         9. This  Agreement  shall be construed and enforced in accordance  with
the laws of the State of Connecticut.

         10. The  foregoing  contains the entire  Agreement  between the parties
pertaining to confidential  DIANON  documents and  information.  No modification
thereof shall be binding upon the parties unless the same is in a writing signed
by the  respective  parties.  This Agreement and all of the terms and conditions
contained  herein  shall  remain in full force  during the period of  employment
notwithstanding any changes in compensation.

         11.  Employee   represents  and  warrants  that  he/she  has  no  other
agreements or  commitments  that would hinder or prevent  performance of his/her
job  responsibilities  with DIANON.  Unless authorized to do so, Employee agrees
not to disclose to DIANON or use in his/her employment with DIANON any invention
or  confidential  information  belonging to any former  employer or to any other
person other than DIANON.

         IN WITNESS WHEREOF,  the parties have entered into this Agreement as of
the date set forth below.

Employee:                                 DIANON SYSTEMS, INC.


     /s/Steven Clayton                    By:       /s/David R. Schreiber
- ------------------------                     ---------------------------------
Steven Clayton                                  David R. Schreiber

Dated:      12/11/96
      ------------------------




                                                                   Exhibit 10.26
                              SEPARATION AGREEMENT


         WHEREAS, DANIEL J. CRONIN III and DIANON SYSTEMS, INC. ("Company") wish
to end the employment  relationship between them and wish to resolve any and all
claims, disputes or causes of action that do or may exist between them;

         NOW  THEREFORE,  in  consideration  of the mutual  covenants  and other
valuable  considerations  contained herein, the Company and DANIEL J. CRONIN III
agree as follows:

         1.  DANIEL J.  CRONIN III  resigns  his  full-time  employment  and his
officer position with the Company effective as of December 6, 1996.

         2. The Company  shall pay DANIEL J. CRONIN III  separation  pay, at his
last rate of base salary subject to applicable  deductions,  for the period four
months  after his  termination  and for so much of the  following  two months as
DANIEL  J.  CRONIN  III has  not  obtained  other  employment  (the  "Separation
Period").  This  separation pay shall be paid in equal  installments  on regular
payroll dates of the Company throughout the Separation Period.

         3. Throughout the Separation  Period,  the Company shall  contribute to
medical coverage for DANIEL J. CRONIN III and his dependents at the same rate it
contributes for active  employees,  provided DANIEL J. CRONIN III and his family
are eligible and elect continuation coverage.

         4. The  Company  shall pay DANIEL J. CRONIN III the bonus he would have
received  under  the  Company's  1996  Management   Incentive  Program  had  his
employment  continued  through the date on which payments under said program are
made.  The  Company  commits  that not less than 70% shall be used for DANIEL J.
CRONIN's individual goals achievement in the calculation of said bonus under the
program's formula.  This payment will be made at the same time payments to other
Management Incentive Program participants are made.

         5. The Company  shall make a  contribution  to DANIEL J.  CRONIN  III's
401(k) plan account for the year 1996.

         6. The Company shall respond to inquiries about DANIEL J. CRONIN III by
prospective  employers by disclosing  only his salary,  date of  employment  and
title.

         7. DANIEL J. CRONIN III acknowledges  his continuing  obligation not to
use or divulge  confidential  Company  documents and information to which he has
had access in the course of his  employment  with the Company.  DANIEL J. CRONIN
III  agrees  that he shall  return to the  Company  and retain no copies of, any
Company  information,  documents  and/or equipment in his possession at the time
his employment with the Company terminates.

         8. DANIEL J. CRONIN III, agrees to make himself reasonably available to
consult with the Company on Information Systems matters up to six days per month
during the Separation  Period.  The Company agrees to reimburse DANIEL J. CRONIN
III for any  reasonable  travel  expenses  he  incurs in order to  fulfill  this
obligation.

         9.  DANIEL  J.  CRONIN  III,  on  behalf  of  himself,  his  executors,
administrators  and assigns,  hereby releases the Company,  its affiliates,  and
their  respective  directors,   officers,  agents,  employees,   benefit  plans,
fiduciaries and  administrators  of such benefit plans and their  successors and
assigns  (hereinafter  "Released  Company  Parties")  from any and all claims or
causes  of  action  of any kind  arising  on or  before  the date he signs  this
Agreement,  other than vested rights under benefit plans, which DANIEL J. CRONIN
III has, had or may have against any of them,  whether or not now known  arising
from DANIEL J. CRONIN III's  recruitment  for employment  with the Company,  his
employment  or officer  position  with the Company,  or the  termination  of his
employment and officer position with the Company,  including without  limitation
any claims under the Age Discrimination in Employment Act.


<PAGE>

         10.  DANIEL J. CRONIN III on behalf of himself,  his heirs,  executors,
administrators  and assigns,  further  agrees never  directly or  indirectly  to
commence or prosecute, or to permit or advise to be commenced or prosecuted, any
action,  proceeding,  or charge against any Released Company Party, in any state
or federal  court,  administrative  agency or arbitral forum with respect to any
matter whether or not now known, for any claim based upon any act,  transaction,
practice,  conduct,  or omission that  occurred  prior to the date he signs this
Agreement,  including but not limited to, rights under the Age Discrimination in
Employment Act or any other federal, state, or local laws prohibiting age, race,
sex, national origin,  religion,  or other forms of  discrimination,  claims for
breach of contract or promissory estoppel or tort, and claims growing out of any
legal restrictions on the Company's right to terminate its employees or officers
which he now has,  or claims to have,  or which at any time  heretofore  had, or
which at any time hereafter may have.

         11. The parties  recognize and agree that this  Agreement  does not and
shall not  constitute  an admission of liability or  wrongdoing  by any Released
Company Party.

         12. The parties agree that, except as necessary to comply and to obtain
compliance with this Agreement,  or to comply with any federal,  state, or local
law, they will not disclose the terms of this Agreement.

         13.  In the event  DANIEL  J.  CRONIN  III  files a claim,  lawsuit  or
complaint against any Released Company Party in any court or governmental agency
with  respect to the claims he has  released  under  this  Agreement,  DANIEL J.
CRONIN  III shall be liable for all costs and  expenses  including  legal  fees,
incurred by any Released Company Party in defense of that action.

         14.  DANIEL J. CRONIN III  represents  that he has  carefully  read and
completely  understands  this  Agreement  and  that  he has  entered  into  this
Agreement  voluntarily after having had an opportunity to consult with his legal
advisors.

         15. DANIEL J. CRONIN III acknowledges that the commitments, waivers and
releases he gives in this  Agreement are in exchange for valuable  consideration
to which he is not otherwise  entitled,  and which constitutes a full accord and
satisfaction of any claims he may have against any Released Company Party.

         16. DANIEL J. CRONIN  acknowledges  that he has been given a reasonable
time to review the waivers and  releases  contained in this  Agreement  prior to
signing it.

         17. This Agreement  constitutes the entire  Agreement of the parties on
the  subject  matter  hereof  and  supersedes  any  and  all  prior  agreements,
understandings or commitments, oral or written.

         18. This Agreement shall be governed by applicable  Federal law and the
laws of the State of Connecticut.



                                    DANIEL J. CRONIN III


   12/24/96                             /s/Daniel J. Cronin III
- -----------------                   ---------------------------------
Dated                               Signature

                                    DIANON SYSTEMS, INC.


    12/23/96                             /s/Kevin C. Johnson
- -----------------                   ---------------------------------
Dated                               By:  Kevin C. Johnson, President





                                                                   Exhibit 10.29

         STOCK AND WARRANT PURCHASE AGREEMENT,  dated as of October 4, 1995 (the
"Agreement"),  among the Gilbert Family Trust (the "Trust"),  the G.S.  Beckwith
Gilbert I.R.A.  Contributory  Account (the "IRA"),  G.S.  Beckwith Gilbert ("Mr.
Gilbert" and,  together with the Trust and the IRA, the  "Purchasers" and each a
"Purchaser") and DIANON Systems, Inc., a Delaware corporation (the "Company").

         WHEREAS  Purchasers wish to purchase from the Company,  and the Company
wishes to sell to Purchasers,  1,000,000  shares (the "Shares") of the Company's
Common Stock, par value $0.01 per share ("Common  Stock"),  and 800,000 two-year
warrants  (the  "Warrants")  entitling  Purchasers  to purchase up to a total of
800,000 shares of Common Stock (the "Warrant Shares");

         WHEREAS  Purchaser and the Company are entering into this  Agreement to
provide  for  such  purchase  and  sale  and to  establish  various  rights  and
obligations  in connection  therewith.  Certain terms used herein are defined in
Section 6.

         NOW,  THEREFORE,  in  consideration  of the  premises  and  the  mutual
covenants herein set forth, the parties agree as follows:

         1.       Purchase and Sale of Shares.

         1.1   Purchase   and  Sale.   Upon  the  terms  set  forth  herein  and
contemporaneously  with the execution of this Agreement,  the Company is selling
to Purchasers,  and Purchasers are purchasing  from the Company,  the Shares and
the Warrants for an aggregate purchase price of $5,612,000.

         1.2 Manner of Payment.  The total purchase price of $5,612,000  payable
at the Closing (as defined  below) to the Company shall be paid as follows:  (a)
$5,316,000 in cash by bank checks of Purchasers payable to the Company;  and (b)
$296,000 in a two-year, 7% promissory note from Mr. Gilbert (the "Note").

         1.3 Time and Place of Closing.  The sale and purchase of the Shares and
the Warrants (the "Closing") shall take place at the offices of Hughes Hubbard &
Reed,  One Battery  Park Plaza,  New York,  New York,  at 10:00 a.m. on the date
hereof.  The date on which the  Closing  is to occur is  hereinafter  called the
"Closing Date."

         1.4 Transactions to be Effected at Closing. At the Closing:

                  (a) the Company  and  Purchasers  shall  execute and deliver a
         registration   rights   agreement   in  the  form  of  Exhibit  A  (the
         "Registration Rights Agreement");

                  (b)  the  Company   shall  deliver  to  Purchasers  a  warrant
         certificate  (in  the  form of  Exhibit  B),  in  definitive  form  and
         registered in the name of Mr. Gilbert,  representing the Warrants being
         purchased by it pursuant hereto;

                  (c) the Company shall deliver to Purchasers stock certificates
         in definitive form, registered in the name of the applicable Purchaser,
         representing the Shares being purchased by it pursuant hereto;

                  (d)  Purchasers   shall   concurrently   pay  to  the  Company
         $5,316,000  by bank  check  or  checks  of  Purchasers  payable  to the
         Company;

                  (e) the Company  shall  deliver to  Purchasers a duly executed
         amendment  (the "Rights  Amendment"),  in the form of Exhibit C, to the
         Rights Agreement,  dated as of April 29, 1994 (the "Rights Agreement"),
         between the Company and American Stock Transfer and Trust Company;


<PAGE>

                  (f) Mr. Gilbert shall deliver to the Company the duly executed
         Note in favor of the  Company in  substantially  the form of Exhibit D;
         and

                  (g)  Purchasers  shall have  received an opinion of counsel to
         the Company substantially in the form of Exhibit E.

         2.   Representations  and  Warranties  of  the  Company.   The  Company
represents and warrants as of the date hereof as follows:

         2.1  Organization  and  Qualification.  Each  of the  Company  and  its
Significant  Subsidiaries  is a corporation  duly organized and existing in good
standing under the laws of the  jurisdiction in which its has  incorporated  and
has the  corporate  power  to own its  respective  property  and to carry on its
respective  business  as now  being  conducted.  Each  of the  Company  and  its
Significant  Subsidiaries  is duly  qualified  as a  foreign  corporation  to do
business and in good standing in every  jurisdiction  in which the nature of the
respective  business  conducted or property owned by it make such  qualification
necessary  and where the  failure  so to qualify  would have a material  adverse
effect  on  the  business  or  financial  possession  of  the  Company  and  its
Subsidiaries  taken as a whole.  The  Company and its  Significant  Subsidiaries
possess all rights, licenses and permits reasonably required for the maintenance
and operation of their respective  material  properties and the conduct of their
respective  material  businesses  as  now  being  maintained  and  operated  and
conducted.

         2.2 Due  Authorization.  The execution and delivery of this  Agreement,
the  Registration  Rights  Agreement,  the Rights Amendment and the issuance and
sale of the  Shares,  the  Warrants  and the  Warrant  Shares by the Company and
compliance by the Company with all the provisions of this Agreement,  the Rights
Amendment,  the Registration  Rights Agreement,  the Warrants and the Shares (a)
are within the corporate powers and authority of the Company, (b) do not require
the approval or consent of any third  party,  (c) do not require the approval or
consent of any  stockholders  of the Company and (d) have been authorized by all
requisite corporate proceedings on the part of the Company. This Agreement,  the
Rights Amendment,  the Warrants and the Registration  Rights Agreement have been
duly  executed  and  delivered by the Company and  constitute  valid and binding
agreements of the Company enforceable in accordance with their respective terms,
except  that (i) such  enforcement  may be  subject to  bankruptcy,  insolvency,
reorganization,  moratorium  and other  similar  laws now or hereafter in effect
relating to creditors'  rights and (ii) the remedy of specific  performance  and
injunctive relief may be subject to equitable  defenses and to the discretion of
the court before which any proceeding  therefor may be brought.  The Company has
furnished  to  Purchasers  true and  correct  copies of the  Company's  Restated
Certificate of Incorporation,  as amended,  and By-laws as in effect on the date
of this  Agreement.  The  Company  has taken all  necessary  action to amend the
Rights  Agreement  (as  defined  in  Section  2.9)  in  order  to  provide  that
Purchasers, upon purchase of the Shares pursuant hereto and upon purchase of the
Warrant  Shares  pursuant to exercise of the  Warrants,  will not  constitute an
"Acquiring  Person"  for  purposes  of  the  Rights  Agreement  hereunder.   The
acquisition  by  Purchasers of the Shares,  the Warrants and the Warrant  Shares
(upon  exercise  of the  Warrants)  has  been  approved  and  authorized  by the
Company's  Board of  Directors,  including  for  purposes  of Section 203 of the
Delaware General Corporation Law.

         2.3 SEC Reports.  The Company has filed all proxy  statements,  reports
and other  documents  required  to be filed by it under the  Exchange  Act after
December  31,  1993  (collectively,  the  "SEC  Reports")  and the  Company  has
furnished  Purchasers  copies of its  Annual  Report on Form 10-K for the fiscal
year ended December 31, 1994, and all proxy statements and reports under Section
13 of the Exchange Act filed by the Company after such date,  each as filed with
the  Commission.  Each  SEC  Report  was  in  substantial  compliance  with  the
requirements  of its  respective  report  form and did not on the date of filing
contain any untrue statement of a material fact or omit to state a material fact
required to be stated  therein or necessary to make the statements  therein,  in
the light of the circumstances under which they were made, not misleading.


<PAGE>

         2.4 Financial  Statements.  The  financial  statements  (including  any
related  schedules  and/or notes)  included in the SEC Reports are in conformity
with the books and records of the Company, have been prepared in accordance with
generally  accepted  accounting  principles  consistently  followed  (except  as
indicated  in the notes  thereto)  throughout  the periods  involved  and fairly
present the consolidated financial condition,  results of operations and changes
in  financial  position  of the  Company  and its  subsidiaries  as of the dates
thereof and for the  periods  ended on such dates (in each case  subject,  as to
interim  statements,  to changes  resulting from year-end  adjustments  (none of
which are material in amount or effect)).

         2.5  Actions  Pending;  Compliance  with Law.  Except as  disclosed  on
Schedule 2.5, there is no action, suit,  investigation or proceeding pending or,
to  the  knowledge  of  the  Company,  threatened  by  any  public  official  or
governmental  authority against the Company or any of its Subsidiaries or any of
their  respective  properties  or assets by or before any court,  arbitrator  or
governmental   body,   department,   commission,   board,   bureau,   agency  or
instrumentality,   which   questions  the  validity  of  this   Agreement,   the
Registration  Rights Agreement,  the Rights Amendment,  or the Warrants or which
are reasonably  likely to result in a Material  Adverse Effect,  and neither the
Company nor any of its  Subsidiaries is in default in any material  respect with
respect to any judgment,  order, writ,  injunction,  decree or award.  Except as
disclosed on Schedule 2.5 or as otherwise  previously  disclosed to  Purchasers,
the  businesses  of the Company and its  Subsidiaries  are in  compliance in all
material respects with applicable Federal, state, local and foreign governmental
laws and  regulations,  including,  without  limitation,  laws  and  regulations
relating   to   employment   practices   (such  as   practices   in  respect  of
discrimination,  health and safety), but excluding any such laws and regulations
described in Section 2.13.

         2.6 Governmental  Consents,  etc. The Company is not required to obtain
any consent,  approval or authorization of, or to make any declaration or filing
with,  any  governmental  authority as a condition to or in connection  with the
valid  execution,  delivery  and  performance  of  this  Agreement,  the  Rights
Amendment,  the Warrants and the  Registration  Rights  Agreement  and the valid
offer,  issue,  sale or delivery of the Shares and the  Warrant  Shares,  or the
performance  by the Company of its  obligations in respect  thereof,  except (a)
with  respect  to  the  transactions  contemplated  by the  Registration  Rights
Agreement,  for filings with the Commission and state securities commissions and
(b) with respect to the transactions contemplated hereby, the filing of a Form D
with  the  Commission  and  with  the  Department  of  Banking  of the  State of
Connecticut.

         2.7 Taxes. The Company and its Subsidiaries  have filed or caused to be
filed all Federal,  state and local income tax returns  which are required to be
filed and have paid or caused to be paid all taxes as shown on said  returns and
on all assessments received by it to the extent that such taxes have become due,
except taxes the validity or amount of which is being contested in good faith by
appropriate  proceedings  and with respect to which adequate  reserves have been
set aside.  No Federal  income tax returns of the  Company and its  Subsidiaries
have been examined and reported on by the Internal Revenue Service (or closed by
applicable statutes). The Company and its Subsidiaries have paid or caused to be
paid, or have established  reserves that the Company  reasonably  believes to be
adequate in all material  respects,  for all tax  liabilities  applicable to the
Company and its  Subsidiaries  for all fiscal years which have not been examined
and reported on by the taxing authorities (or closed by applicable statues).

         2.8  Conflicting   Agreements  and  Charter  Provisions.   Neither  the
execution and delivery of this Agreement, the Rights Amendment, the Warrants and
the Registration Rights Agreement nor the issuance of the Shares and the Warrant
Shares nor fulfillment of nor compliance with the terms and provisions hereof or
thereof will  conflict  with or result in a breach of the terms,  conditions  or
provisions  of, or give rise to a right of  termination  under,  or constitute a
default  under,  or result in any  violation  of, the  Restated  Certificate  of
Incorporation, as amended, or By-Laws of the Company or any mortgage, agreement,
instrument,  order, judgment,  decree, statute, law, rule or regulation to which
the Company or any of its  Subsidiaries or any of their  respective  property is
subject.  The  acquisition  by  Purchasers  of the Shares,  the Warrants and the
Warrant  Shares are not and will not be subject to the  requirements  of Article
Seventh of the Company's Restated Certificate of Incorporation.


<PAGE>

         2.9  Capitalization.  The  authorized  capital  stock  of  the  Company
consists of (a)  20,000,000  shares of Common  Stock,  of which,  as of the date
hereof,  5,311,450  shares are issued and  outstanding and no shares are held in
its treasury,  and (b) 5,000,000  shares of preferred stock, par value $0.01 per
share, of the Company, no shares of which are issued and outstanding, and all of
such  outstanding  shares  have  been  validly  issued  and are  fully  paid and
nonassessable.  No  class  of  capital  stock  of the  Company  is  entitled  to
preemptive  rights.  As of October 3, 1995,  (i) 676,679  shares of Common Stock
were issuable upon the exercise of outstanding  employee  options (the "Employee
Options")  pursuant to the Company's 1991 Stock Incentive Plan, Outside Director
Stock  Compensation  Plan  (the  "Directors  Plan")  and  certain  other  option
agreements (collectively,  the "Incentive Plans"), (ii) 154,017 shares of Common
Stock,  available  for any future  grants of stock  options  under the Incentive
Plans,  were  contingently  issuable to employees  under the Incentive Plans and
(iii) 100,000 shares of Series A Junior Participating Preferred Stock, par value
$0.01 per share, of the Company ("Series A Stock") were reserved pursuant to the
Rights  Agreement.  Except as set forth above and pursuant to the Warrants,  the
Incentive  Plans and the Rights  Agreement,  there are no  outstanding  options,
warrants,  scrip,  rights to subscribe to, calls or commitments of any character
whatsoever  relating to, or securities or rights convertible into, shares of any
capital stock of the Company,  or  contracts,  commitments,  understandings,  or
arrangements  by which the  Company is or may become  bound to issue  additional
shares of its  capital  stock or  options,  warrants  or rights to  purchase  or
acquire any shares of its capital stock.

         2.10 Status of Shares.  The Shares and the Warrants being issued on the
date hereof have been duly authorized by all necessary  corporate  action on the
part of the Company (no consent or approval of  stockholders  being  required by
law, the Restated  Certificate of Incorporation,  as amended,  or By-Laws of the
Company or otherwise), and such Shares and such Warrants, upon payment therefore
as provided herein,  will be validly issued,  fully paid and nonassessable,  and
the issuance of such Shares and such  Warrants is not and will not be subject to
preemptive  rights of any other  stockholder of the Company.  The Warrant Shares
have been duly authorized by all necessary  corporate  action on the part of the
Company  (no  consent or approval of  stockholders  being  required by law,  the
Restated Certificate of Incorporation,  as amended, or By-Laws of the Company or
otherwise), and such Warrant Shares have been validly reserved for issuance, and
upon  issuance  upon  exercise  of the  Warrants  and upon  payment  therefor as
provided in the Warrants will be validly issued and outstanding,  fully paid and
nonassessable.

         2.11 ERISA.  No accumulated  funding  deficiency (as defined in Section
302 of ERISA and  Section 412 of the Code),  whether or not waived,  exists with
respect to any Plan (as  defined  below)  (other than a  Multiemployer  Plan (as
defined below)).  No liability to the Pension Benefit  Guaranty  Corporation has
been incurred with respect to any Plan (other than a Multiemployer  Plan) by the
Company or any of its  Subsidiaries  which is or would be materially  adverse to
the Company and its Subsidiaries  taken as a whole.  Neither the Company nor any
of its  Subsidiaries has maintained a Plan which is subject to Title IV of ERISA
or has contributed to a  Multiemployer  Plan. The execution and delivery of this
Agreement and the issue and sale of the Shares and the Warrants will not involve
any transaction  which is subject to the prohibitions of Section 406 of ERISA or
in connection with which a tax could be imposed  pursuant to Section 4975 of the
Code.  As used in this  Section  2.12,  the term "Plan"  shall mean an "employee
pension benefit plan" (as defined in Section 3(2) of ERISA) which is or has been
established or maintained,  or to which  contributions are or have been made, by
the Company or by any trade or  business,  whether or not  incorporated,  which,
together  with the  Company,  is under  common  control  or  treated as a single
employer,  as  described  in  Section  414(b) or (c) of the  Code;  and the term
"Multiemployer  Plan"  shall mean any Plan which is a  "multiemployer  plan" (as
such term is defined in Section 4001(a)(3) of ERISA).

         2.12  Possession  of  Franchises,  Licenses,  etc.  The Company and its
Subsidiaries possess all franchises,  certificates,  licenses, permits and other
authorizations   from   governmental   political   subdivisions   or  regulatory
authorities,  free  from  burdensome  restrictions,  that are  necessary  in any
material  respect  for  the  ownership,   maintenance  and  operation  of  their
respective  properties  and  assets,  and  neither  the  Company  nor any of its
Subsidiaries is in violation of any thereof in any material respect.

         2.13 Environmental Laws.

                  (a) The Company and its  Subsidiaries are in compliance in all
         material respects with all applicable federal, state or local statutes,
         codes,  rules  or  regulations  relating  to the  environment,  natural
         resources  and public or  employee  health  and safety  ("Environmental
         Laws");

    
<PAGE>

              (b) No judicial or  administrative  proceedings are pending or
         threatened  against  the  Company  and its  Subsidiaries  alleging  the
         violation of any  Environmental Law and no notice from any governmental
         body or other  person has been  served  upon the  Company or any of its
         Subsidiaries claiming any violation of any Environmental Laws; and

                  (c) All substances, materials or wastes which are regulated by
         federal, state or local government,  including, without limitation, any
         substance,  material or waste which is defined as a "hazardous  waste,"
         "hazardous  material,"  "hazardous  substance," "toxic waste" or "toxic
         substance" under any provision of Environmental  Law, used or generated
         by the  Company  or any of its  Subsidiaries  have been  stored,  used,
         treated and  disposed  of by them or on their  behalf in such manner as
         not to  result  in  Environmental  Costs  and  Liabilities,  which  are
         reasonably  likely  to  exceed  $100,000.   "Environmental   Costs  and
         Liabilities"  means  any  losses,  liabilities,  obligations,  damages,
         fines,  penalties,  judgments,  actions,  claims,  costs  and  expenses
         (including,  without  limitation,  fees,  disbursements and expenses of
         legal  counsel,  experts,  engineers and  consultants  and the costs of
         investigation and feasibility studies,  remedial or removal actions and
         cleanup  activities)  arising  from or under any  Environmental  Law or
         order or  contract  with  any  federal,  state  or  local  governmental
         authority  or other  person  with  respect  to the  enforcement  of any
         Environmental Law.

         2.14  Election of  Director.  Mr.  Gilbert has been duly elected by the
Board of Directors of the Company to serve as a director on that Board effective
upon the issuance of, and payment for, the Shares and the Warrants.

         2.15   Subsidiaries.   The  Company  does  not  have  any   Significant
Subsidiaries.

         2.16 No Undisclosed  Liabilities.  As of June 30, 1995, the Company did
not have any material  indebtedness or liability of any nature (whether known or
unknown and whether accrued, absolute,  contingent or otherwise, and whether due
or to become  due) which is not shown on the  Company's  June 30,  1995  balance
sheet set forth in the SEC Reports (the "Balance Sheet") or the notes thereto or
disclosed herein or in any document  delivered to Purchasers  hereunder upon the
execution and delivery  hereof.  Except as set forth in the Balance  Sheet,  the
Company does not have outstanding any material  indebtedness or liability,  nor,
to the  knowledge  of the  Company,  there is no  condition  or event that could
result in any material indebtedness or liability,  of any kind, whether accrued,
absolute,  contingent or otherwise,  that may arise or be incurred other than in
the ordinary course of business,  whether or not such  indebtedness or liability
would  have been  required  to be  disclosed  in a  balance  sheet  prepared  in
accordance with United States generally accepted accounting principles.

         2.17  Default.  The Company is not in default,  or, to the knowledge of
the  Company,  alleged to be in default,  with respect to any  judgment,  order,
writ,  injunction  or decree of any court or any  federal,  state,  municipal or
other governmental authority,  department,  commission, board or agency or other
entity, where such default would have a material adverse effect on the financial
condition, results of operations, business, properties, assets or liabilities of
the Company and its Subsidiaries taken as a whole (a "Material Adverse Effect").
The Company is not in breach or default,  or, to the  knowledge  of the Company,
alleged  to be in  breach  or  default,  under  any  lease,  license,  contract,
agreement or instrument, where such default would have a Material Adverse Effect
and the Company  does not know of any  condition  or event  which is  reasonably
likely to cause or create a default or defaults  under any such lease,  license,
contract,  agreement or  instrument,  where such  default  would have a Material
Adverse  Effect.  The  Company  does not know of any other  party to any  lease,
license,  contract,  agreement or instrument to which the Company is a party and
which is material to the Company's  business that is in default  thereunder and,
to the knowledge of the Company, there exists no condition or event which, after
notice or lapse of time or both,  would  constitute a default of any other party
to any such material lease, license, contract, agreement or instrument.


<PAGE>

         2.18 No Material Adverse Changes. Except as set forth in Schedule 2.18,
since June 30,  1995,  there has not been,  occurred or arisen (i) any  material
adverse  change in the financial  condition,  results of  operations,  business,
properties, assets or liabilities of the Company and its Subsidiaries taken as a
whole, (ii) any damage or destruction in the nature of a casualty loss,  whether
covered by insurance or not, adversely  affecting any property of the Company or
its  Subsidiaries  which  damage or  destruction  would have a Material  Adverse
Effect, (iii) any actual or, to the knowledge of the Company,  threatened strike
or other labor  dispute  which strike or dispute  would have a Material  Adverse
Effect,  (iv) any  extraordinary  loss (as  defined  in  Opinion  No.  30 of the
Accounting  Principles  Board of the  American  Institute  of  Certified  Public
Accountants  and any  amendments  or  interpretations  thereof)  suffered by the
Company or any Subsidiary, which, individually or in the aggregate, would have a
Material  Adverse  Effect and (v) any waiver by the Company or any Subsidiary of
any  right or rights  which,  individually  or in the  aggregate,  would  have a
Material Adverse Effect.

         2.19 Registration Rights. There are no outstanding  effective rights to
demand or require  registration  under a  registration  statement  of any of the
Company's securities under the Securities Act.

         2.20 Patents,  etc. The Company owns or has valid and enforceable right
to use all rights under any patent,  trademark,  trade name,  copyright or other
intellectual  property  (or  any  application  or  registration  respecting  any
thereof),  material to the conduct of its business as such business is currently
being conducted,  and, to the knowledge of the Company,  neither the Company nor
any Subsidiary is infringing or alleged to be infringing the rights of any third
party with  respect to any of the  foregoing,  which  infringement  would have a
Material Adverse Effect.

         2.21 Disclosures.  The Company has not knowingly  furnished  Purchasers
with any materially false or misleading  information concerning the Company, its
business or financial condition or knowingly omitted to inform Purchasers of any
facts  necessary to make the  information  that was furnished to Purchasers  not
misleading in a material manner.

         3. Representations and Warranties of Purchaser.  Purchasers jointly and
severally represent and warrant as of the date hereof as follows:

         3.1  Due  Authorization.  Each  Purchaser  has  all  right,  power  and
authority  to enter  into this  Agreement  and to  consummate  the  transactions
contemplated  hereby.  Each Purchaser that is a trustee under a trust agreement,
trust indenture or other  instrument  creating the trust of which such Purchaser
is a trustee (i) is acting in his capacity as trustee,  (ii) has the power under
such trust  agreement,  trust  indenture  or other  instrument  to purchase  his
respective  Shares as trustee and to enter into this  Agreement on behalf of the
trust and (iii) if acting as trustee under a trust agreement, trust indenture or
other  instrument  other than a will,  is the trustee  named in such  agreement,
indenture  or other  instrument,  or has been duly  appointed  as  successor  or
substitute  trustee  pursuant to the provisions of such agreement,  indenture or
other instrument. The execution and delivery of this Agreement by each Purchaser
and the consummation by each Purchaser of the transactions  contemplated  hereby
have been duly  authorized by all necessary  action on behalf of such Purchaser.
This Agreement has been duly executed and delivered by each Purchaser or, if any
Purchaser is a trustee  acting in his capacity as trustee,  by such Purchaser as
trustee of the trust in which the Shares are to be held, and constitutes a valid
and binding agreement of such Purchaser, or, if Purchaser is a trustee acting in
his capacity as trustee,  constitutes the legal, valid and binding obligation of
such  trust in which any Shares and any  Warrant  Shares are held,  in each case
enforceable in accordance with its terms,  except that (a) such  enforcement may
be  subject  to  bankruptcy,  insolvency,  reorganization,  moratorium  or other
similar laws now or hereafter in effect  relating to  creditors'  rights and (b)
the remedy of specific  performance  and injunctive and other forms of equitable
relief may be subject to equitable  defenses and to the  discretion of the court
before  which any  proceeding  therefor  may be brought.  The Note has been duly
executed  and  delivered  by Mr.  Gilbert  and  constitutes  a valid and binding
agreement of Mr. Gilbert  enforceable in accordance with its terms,  except that
(i) such enforcement may be subject to bankruptcy,  insolvency,  reorganization,
moratorium  or other  similar  laws  now or  hereafter  in  effect  relating  to
creditors' rights and (ii) the remedy of specific performance and injunctive and
other forms of equitable relief may be subject to equitable  defenses and to the
discretion of the court before which any proceeding therefor may be brought. Mr.
Gilbert has full power and  authority to execute and deliver  this  Agreement on
behalf of the Trust and the IRA.


<PAGE>

         3.2 Conflicting Agreements and Other Matters. Neither the execution and
delivery of this Agreement or the Note nor the  performance by each Purchaser of
their  respective  obligations  hereunder or under the Note will conflict  with,
result in breach of the terms, conditions or provisions of, constitute a default
under, result in the creation of any mortgage,  security interest,  encumbrance,
lien or  charge  of any  kind  upon  any of the  properties  or  assets  of each
Purchaser, or, if any Purchaser is a trustee or trustees acting in his, her, its
or their  capacity or  capacities as trustee or trustees,  the trust  agreement,
trust indenture or other  instrument  creating the trust or trusts of which such
Purchaser  is trustee or  trustees,  or require any  consent,  approval or other
action  by or any  notice  to or  filing  with any  court or  administrative  or
governmental  body,  pursuant to any  agreement,  instrument,  order,  judgment,
decree,  statute,  law,  rule or  regulation  by which each  Purchaser is bound,
except for filings after the Closing of a Schedule 13D pursuant to Section 13(d)
of the Exchange Act.

         3.3  Acquisition  for  Investment;  Source of Funds.  Each Purchaser is
acquiring its Shares and  Warrants,  if any, for its own account for the purpose
of  investment  and  not  with a view  to or for  sale in  connection  with  any
distribution  thereof,  and each  Purchaser has no present  intention or plan to
effect any distribution of the Shares or the Warrant Shares;  provided, that the
disposition of each Purchaser's property shall at all times be and remain within
its control and subject to the provisions of this Agreement,  the Warrants,  the
Note and the Registration Rights Agreement. Each Purchaser represents that it is
(a) an  "accredited  investor"  as that term is defined in  Regulation  D of the
Securities Act and (b) a resident of the State of Connecticut.

         3.4 Ownership of  Securities.  At the date hereof neither any Purchaser
nor any of their respective Affiliates or Associates (collectively, the "Gilbert
Entities")  Beneficially  Owns directly or, to the knowledge of all  Purchasers,
indirectly (or have any option or other right to acquire), any securities of the
Company other than the Shares and the Warrants,  if any, being purchased by each
Purchaser  hereunder  and none of the Gilbert  Entities has any  arrangement  or
understanding  with any Person with  respect to  acquiring,  holding,  voting or
disposing of the Shares or any other Voting Securities.

         3.5 Voting of Shares and  Warrant  Shares.  Mr.  Gilbert has the right,
individually  and without the consent of any other trustee,  to vote and dispose
of any Shares or Warrant  Shares  that will be at any time held by the IRA.  Mr.
Gilbert and his wife together  have the right,  without the need for the consent
of any other  trustee,  to vote and dispose of any Shares or Warrant Shares that
will be at any time held by the Trust.

         3.6 Brokers or Finders. Except for certain fees previously disclosed by
Purchasers to the Company which the Company has agreed to pay, no agent, broker,
investment  banker or other firm or Person,  including any of the foregoing that
is an  Affiliate  of any  Purchaser,  is or will be entitled to any  broker's or
finder's  fee  or any  other  commission  or  similar  fee  from  Purchasers  in
connection with any of the transactions contemplated by this Agreement.

         3.7  Investment  Purpose.  Purchasers  are  acquiring  the Shares,  the
Warrants  and the  Warrant  Shares for  purposes of  investment  and in order to
acquire a significant equity interest in the Company and have no current plan or
intention of seeking to acquire control of the Company, except that Mr. Gilbert,
as a director of the Company,  will participate in and influence the formulation
of the business plans and  strategies of the Company.  The Schedule 13D filed by
Purchasers  pursuant  to Rule  13d-1  under the  Exchange  Act  reporting  their
acquisition  of the  Shares,  the  Warrant  and  the  Warrant  Shares  shall  be
consistent with the representations set forth in this Section 3.7.

         4. Covenants.

         4.1 Financial  Statements and Other Reports. The Company covenants that
it will deliver to Mr. Gilbert so long as the Gilbert Entities  Beneficially Own
Voting Securities representing 5% or more of the Total Voting Power:

                  (a) as soon as  practicable  and in any  event  within 45 days
         after the end of each  quarterly  period (other than the last quarterly

<PAGE>

         period) in each fiscal year, a  consolidated  statement of earnings and
         retained earnings and a consolidated  statement of changes in financial
         position of the Company  and its  Subsidiaries  for the period from the
         beginning of the then current  fiscal year to the end of such quarterly
         period,  and a  consolidated  balance  sheet  of the  Company  and  its
         Subsidiaries as of the end of such quarterly  period,  setting forth in
         each case in comparative form figures for the  corresponding  period or
         date  in the  preceding  fiscal  year,  all in  reasonable  detail  and
         certified by an authorized financial officer of the Company, subject to
         changes resulting from year-end  adjustments;  provided,  however, that
         delivery pursuant to clause (c) below of a copy of the Quarterly Report
         on Form 10-Q of the Company for such  quarterly  period  filed with the
         Commission  shall be deemed to satisfy the  requirements of this clause
         (a);

                  (b) as soon as  practicable  and in any  event  within 90 days
         after the end of each fiscal year, a consolidated statement of earnings
         and  retained  earnings  and a  consolidated  statement  of  changes in
         financial  position of the Company and its  Subsidiaries for such year,
         and a consolidated balance sheet of the Company and its Subsidiaries as
         of the end of such year, setting forth in each case in comparative form
         the  corresponding  figures  from the  preceding  fiscal  year,  all in
         reasonable  detail and  examined  and  reported  on by Arthur  Andersen
         L.L.P. or other independent public  accountants of recognized  standing
         selected by the Company;  provided,  however, that delivery pursuant to
         clause  (c)  below of a copy of the  Annual  Report on Form 10-K of the
         Company for such fiscal year filed with the Commission  shall be deemed
         to satisfy the requirements of this clause (b);

                  (c) promptly  upon  transmission  thereof,  copies of all such
         financial statements, proxy statements, notices and reports as it shall
         send to its stockholders and copies of all such registration statements
         (without  exhibits),  other than  registration  statements  relating to
         employee benefit or dividend  reinvestment  plans, and all such regular
         and periodic reports as it shall file with the Commission; and

                  (d) with reasonable  promptness,  such other financial data of
         the Company and its Subsidiaries as Mr. Gilbert may reasonably request.

         4.2 Inspection of Property.  The Company covenants that, so long as the
Gilbert Entities  Beneficially Own Voting Securities  representing 5% or more of
the Total Voting Power, it will permit  representatives  of Mr. Gilbert to visit
and inspect, at Mr. Gilbert's expense,  any of the properties of the Company and
its  Subsidiaries,  to examine the  corporate  books and make copies or extracts
therefrom  and to discuss the affairs,  finances and accounts of the Company and
its  Subsidiaries  with  the  principal  officers  of the  Company,  all at such
reasonable times and as often as Mr. Gilbert may reasonably  request;  provided,
however,  that the  foregoing  shall be subject to  compliance  with  reasonable
safety requirements and shall not require the Company or any of its Subsidiaries
to permit any inspection  which in the reasonable  judgment of the Company would
result  in the  disclosure  of any trade  secrets  or  violate  any  statute  or
regulation with respect to  confidentiality  or security.  Each Purchaser agrees
not to disclose to any Person any information or data obtained by it pursuant to
this Section 4.2 or Section  4.1(a)  until such  information  or data  otherwise
becomes  publicly  available or except  pursuant to a valid  subpoena,  judicial
process or its  equivalent;  provided,  that each such Purchaser shall have used
its best efforts to give the Company advance notice of such subpoena or judicial
process so that the Company may seek an appropriate protective order.

         4.3 Exchange of Stock and Warrant  Certificates.  The Company covenants
that it shall,  at its expense,  promptly  upon  surrender  of any  certificates
representing shares of Common Stock or the Warrants at the office of the Company
referred to in, or designated  pursuant to, Section 7.5,  execute and deliver to
each Purchaser a new certificate or certificates in  denominations  specified by
such  Purchaser  for an aggregate  number of shares of Common Stock or number of
Warrants,  as the case may be,  equal to the  number of shares of such  stock or
number  of  Warrants,  as the  case  may  be,  represented  by the  certificates
surrendered.


<PAGE>

         4.4  Lost,   Stolen,   Destroyed   or   Mutilated   Stock  and  Warrant
Certificates.  Upon receipt of evidence satisfactory to the Company of the loss,
theft,  destruction or mutilation of any  certificate for shares of Common Stock
or the Warrants and, in the case of loss, theft or destruction, upon delivery of
an indemnity  satisfactory  to the Company or, in the case of  mutilation,  upon
surrender and cancellation thereof, the Company shall issue a new certificate of
like tenor of a number of shares of Common Stock or number of  Warrants,  as the
case may be,  equal to the number of shares of such stock or number of Warrants,
as the case may be,  represented by the certificate lost,  stolen,  destroyed or
mutilated.

            4.5 Board Representation.  The Company shall cause Mr. Gilbert to be
included in the slate of nominees  recommended  by its Board of Directors to the
Company's  stockholders for election as a director at each annual meeting of the
stockholders of the Company and shall seek to cause the election of Mr. Gilbert,
including soliciting proxies in favor of the election of Mr. Gilbert;  provided,
that,  Mr. Gilbert shall not be entitled to be included in the slate of nominees
subsequently  recommended  by the  Board  of  Directors  of the  Company  to the
Company's  stockholders  for  election as directors to the Board of Directors of
the  Company  if  the  Gilbert  Entities   Beneficially  Own  Voting  Securities
representing less than 5% of the Total Voting Power (determined as of the record
date for each annual meeting of stockholders of the Company). For so long as Mr.
Gilbert has rights  under this Section  4.5,  the  Company's  Board of Directors
shall elect and nominate for election to such Board,  as soon as possible and in
any event prior to the next annual  meeting of the Company's  stockholders,  one
person (in  addition to the  Incumbent  Directors  as of the date hereof and Mr.
Gilbert and their successors) reasonably acceptable to all directors.

            4.6  Limitation  on  Transactions   with  Affiliates.   The  Company
covenants  that,  so long as Voting  Securities  representing  5% or more of the
Total Voting Power are Beneficially  Owned by the Gilbert  Entities,  unless Mr.
Gilbert otherwise consents in writing, the Company will not, and will not permit
any of its  Subsidiaries  to,  conduct any  material  business or enter into any
material  transaction  with any Affiliate of the Company (other than Mr. Gilbert
or any of its  Affiliates or any Subsidiary of the Company all the capital stock
of which except for  directors  qualifying  and similar  shares are owned by the
Company)  unless the terms thereof are no less  favorable to the Company or such
Subsidiary than it could obtain in a comparable arm's-length  transaction with a
Person not an affiliate of the Company.

            4.7 Availability of Shares.  The Company  covenants that, so long as
the Company has any  obligations  under the  Warrants to issue  shares of Common
Stock, the Company, in order to satisfy its obligations under the Warrants, will
keep available for issuance a number of shares of authorized but unissued Common
Stock which may be purchased thereunder.

            4.8 Stockholder Meeting. At the first annual meeting of stockholders
after the date  hereof,  the Company  shall  submit a proposal to the  Company's
stockholders  (together with a recommendation  to the Company's  stockholders by
the Company and its Board to approve such  proposal)  to enable the  Purchasers'
Voting Limit (as defined in Section 5.1(ii)) to be increased to 20% of the Total
Voting  Power (which  increase  reflects  the  agreement of the parties  without
giving  effect to any  requirements  of the National  Association  of Securities
Dealers) and the Company and Board of Directors  shall use their best efforts to
obtain such approval.  If the Company's  stockholders approve such proposal by a
majority of the total votes cast on the  proposal,  the Company shall then enter
into an appropriate  amendment of this Agreement with Purchasers to increase the
Purchasers'  Voting Limit to 20% of the Total  Voting  Power.  If the  Company's
stockholders  do not approve such  proposal,  Mr.  Gilbert  shall have the right
within 30 days (or, if such transaction  would result in liability under Section
16(b) of the Exchange Act, such longer period, up to six months from the date of
purchase of the  Warrants,  as may be necessary to avoid such  liability)  after
such  stockholders'  meeting  to  rescind  some  or  all of  the  Warrants  then
outstanding and upon such rescission the Company shall pay Mr. Gilbert an amount
equal to $1.52 per  Warrant  in cash and  cancel a pro rata  portion of the then
outstanding principal amount of the Note.


<PAGE>

            5.    Standstill Provisions.

            5.1 Acquisition of Voting Securities.  Until the earliest of (a) the
seventh  anniversary of the date hereof,  (b) such date as the Gilbert  Entities
cease to Beneficially Own Voting Securities representing 5% or more of the Total
Voting  Power,  and (c) the  occurrence  of a Change in Control or a Rights Plan
Event  (the  earliest  of  such  dates  being  referred  to as  the  "Standstill
Termination Date") and subject to the further provisions hereof,  each Purchaser
covenants and agrees that:

                  (i) The Gilbert  Entities  will not,  directly or  indirectly,
         without the prior written consent of the Company,  Beneficially Own any
         Voting Securities except for (A) the Shares, (B) shares of Common Stock
         issuable  upon  exercise of the  Warrants,  (C) shares of Common  Stock
         issuable  upon  exercise of options  granted to Mr.  Gilbert  under the
         Directors Plan or any other shares of Common Stock or rights to acquire
         Common Stock made  available to  non-employee  directors of the Company
         pursuant to Company plans and (D) additional  Voting  Securities of the
         Company  so long as the  Voting  Power  of all such  additional  Voting
         Securities  Beneficially  Owned by the Gilbert Entities,  together with
         the Voting Power of the shares  referred to in clauses (A), (B) and (C)
         then  Beneficially  Owned by the Gilbert Entities  (calculated  without
         giving effect to paragraph (ii) of this Section 5.1), does not equal or
         exceed 25% of the Total Voting Power;

                  (ii)  Subject  to  Section  4.8,  if at any time  the  Gilbert
         Entities  Beneficially  Own Voting  Securities  representing  more than
         1,056,978 votes ("Purchasers' Voting Limit"), then the Gilbert Entities
         shall  take such  action  as shall be  required  so that all  shares of
         Voting   Securities   Beneficially   Owned  by  the  Gilbert   Entities
         representing  votes in  excess  of such  number  are  voted in the same
         proportion as the votes cast by other  holders of Voting  Securities on
         all  matters  to be  voted  on by  the  holders  of  Voting  Securities
         (including,  without  limitation,  matters relating to mergers or other
         business  combinations).  Notwithstanding  the  foregoing,  the Gilbert
         Entities  shall be free to vote all of their Voting  Securities in such
         manner as they determine in their sole  discretion  with respect to any
         Low Return Transaction (as defined in Section 5.4(b)); and

                  (iii) The Gilbert Entities (A) shall be present,  in person or
         by proxy,  at all  stockholders'  meetings  of the  Company so that all
         outstanding  Voting  Securities   Beneficially  Owned  by  the  Gilbert
         Entities shall be counted for the purpose of  determining  the presence
         of a quorum at such meetings and (B) subject to Section 5.1(ii), in any
         election of directors of the Company, shall vote all outstanding Voting
         Securities  Beneficially Owned by the Gilbert Entities for the election
         of the Company's nominees as directors of the Company;  provided,  that
         the Company has complied with its obligations set forth in Section 4.5.

         5.2 Restrictions on Transfer. Prior to the Standstill Termination Date,
the Gilbert Entities shall not, directly or indirectly,  sell, transfer, pledge,
encumber  or  otherwise  dispose  of   (collectively,   "Transfer")  any  Voting
Securities  or the  Warrants or any  incidents  of  Beneficial  Ownership of any
Voting  Securities  or  Warrants  except  for (i)  Transfers  after  the  second
anniversary  of the date  hereof of shares of Common  Stock  pursuant to (x) the
exercise  of the  registration  rights  set  forth  in the  Registration  Rights
Agreement or (y) a transaction  that  complies with the volume,  time period and
manner of sale provisions contained in Rules 144(e) and (f) under the Securities
Act as in effect at the time of such  transaction;  provided,  that, except with
respect to underwritten offerings pursuant to the Registration Rights Agreement,
the Gilbert  Entities shall use their best efforts (which shall include advising
any broker of the  provisions  of this  Section 5.2 but shall not require  undue
investigation  on the part of the Gilbert  Entities)  so that no such  Transfers
under this clause (i) are made knowingly to any Person (including its Affiliates
and any Person or entities which are, to Purchasers'  knowledge after inquiry of
the Company,  part of any 13D Group which includes such transferee or any of its
Affiliates) that, after giving effect to such Transfer,  would  Beneficially Own
Voting Securities  representing greater than 10% of the Total Voting Power, (ii)

<PAGE>

Transfers of shares of Common Stock pursuant to any bona fide tender or exchange
offer to acquire shares of Common Stock;  provided,  that,  during the first two
years after the date hereof, such offer has been approved and recommended by the
Company's  Board  of  Directors  or  (iii)  Transfers  to an  Affiliate  of  any
Purchaser;  provided,  that such Affiliate becomes a signatory to, and agrees to
be bound by, this Agreement.

         5.3 Other Matters.  Each Purchaser  covenants and agrees that until the
Standstill   Termination   Date,  except  solely  by  virtue  of  Mr.  Gilbert's
representation  on the Board of  Directors of the Company as provided in Section
4.5 hereof:

                  (a) Neither any Purchaser nor any other Gilbert Entity thereof
         shall  deposit any Voting  Securities  in a voting trust or subject any
         Voting  Securities to any  arrangement or agreement with respect to the
         voting of such Voting  Securities  or other  agreement  having  similar
         effect  (other than a voting  trust,  arrangement  or agreement  solely
         among the Purchasers and their Affiliates).

                  (b) Neither any Purchaser  nor any other Gilbert  Entity shall
         solicit proxies or become a "participant" in a "solicitation"  (as such
         terms  are  defined  in  Regulation  14A  under  the  Exchange  Act) in
         opposition  to the  recommendation  of the majority of the directors of
         the Company with respect to any matter other than any charter or by-law
         amendment  to be voted upon by the  Company's  stockholders  that would
         adversely  affect the rights of any such Purchaser,  Mr. Gilbert or any
         other  Gilbert  Entity under this  Agreement  or  adversely  affect the
         rights of any such  Purchaser,  Mr. Gilbert or any other Gilbert Entity
         as a holder of Voting Securities in a discriminatory manner.

                  (c) Neither any Purchaser nor any other Gilbert Entity thereof
         shall form,  join or otherwise  participate in a 13D Group or otherwise
         act in concert  with any other  Person who is not a Gilbert  Entity for
         the  purpose  of  acquiring,  holding,  voting or  disposing  of Voting
         Securities.

                  (d) Other than  pursuant to a direct  request by the  Company,
         neither any Purchaser nor any other Gilbert  Entity thereof shall offer
         or propose (i) to enter into,  directly  or  indirectly,  any merger or
         other  business  combination  involving the Company,  (ii) to purchase,
         directly or indirectly, a material portion of the assets of the Company
         or (iii) to acquire any Voting  Securities if such acquisition would be
         inconsistent with Section 5.1 hereof.

                  (e) Neither any Purchaser nor any other Gilbert Entity thereof
         shall (i) disclose any intention, plan or arrangement inconsistent with
         the foregoing or (ii) advise,  assist (including by knowingly providing
         or arranging  financing  for that  purpose) or knowingly  encourage any
         other Person in connection with any of the foregoing.

         5.4  Notice  of  Certain  Third  Party  Transactions.   (a)  Until  the
Standstill  Termination  Date, the Company shall give Purchasers  written notice
within  two  business  days  following  receipt  by  the  Company  of any of the
following:  (i) any written or oral  notice from any Person or group  couched in
such terms as to put the Company  reasonably  on notice of the  likelihood  that
such  Person or groups has  acquired  or is  proposing  to acquire any shares of
Voting  Securities  which results in, or, if  successful,  would result in, such
persons  or group  owning or having  the right to  acquire  more than 15% of the
Total Voting  Power;  (ii) any notice under the HSR Act relating to the Company;
or (iii) any  statement  on  Schedule  13D or Schedule  14D-1 (or any  successor
schedule  or form to such  schedules)  under the  Exchange  Act  relating to any
Voting  Securities  of the Company.  In its written  notice to  Purchasers,  the
Company shall disclose the material terms of such  transaction,  except that the
Company need not disclose the name of the inquirer, purchaser or offeror, as the
case may be. The Company may not enter into any definitive agreement relating to
any such transaction until ten (10) business days have elapsed after Purchasers'
receipt of the  Company's  notice under this Section  5.4(a).  The Company shall
have no obligation to update the information contained in any such notice.


<PAGE>

         (b) If the  Company  desires to enter into a merger,  consolidation  or
other  business  combination  transaction  in which the Company would not be the
surviving  corporation or in which the Company's  outstanding  Voting Securities
were to be changed or exchanged for cash, stock or assets of another Person,  or
50% or more of the Company's  capital stock  outstanding  immediately after such
merger,  consolidation or other business  combination  transaction  would not be
owned by the  stockholders  of the  Company  immediately  prior to such  merger,
consolidation or other business combination  transaction or all or substantially
all of the Company's  assets or earning  power would be sold,  the Company shall
give  Purchasers  written  notice  of such  proposed  transaction  (a  "Proposed
Transaction")  and the Company shall not enter into an agreement with respect to
such Proposed Transaction and shall negotiate in good faith with Purchasers (but
shall not be precluded  from  pursuing any such Proposed  Transaction),  in each
case for a period of fifteen  (15)  business  days after the date of such notice
with  a view  towards  reaching  a  mutually  beneficial  transaction  with  the
Purchasers.  The  Company  shall have no  obligation  to update the  information
contained in such notice unless the previously noticed terms are made materially
less  favorable to the Company,  in which case the  preceding  and this sentence
shall apply to such revised transaction. During such 15 business day period, the
Company and the Purchasers shall keep confidential  (subject to the requirements
of applicable  securities  laws) the fact that such  negotiations  are occurring
(including the terms discussed) and shall make no direct or indirect  disclosure
thereof to any other Person (other than their  respective  advisers).  If, after
such 15 business day period,  the Company  enters into an agreement with respect
to such Proposed Transaction and, under the terms of such Proposed  Transaction,
Purchasers  would receive  proceeds in an amount that is less than the amount of
their cash investment in the Shares,  the Warrants and the Warrant Shares plus a
return on such  investment at the compounded rate of 10% per annum from the date
of investment (which amount, in the case of a transaction involving the purchase
of or an exchange for less than all of such Shares, Warrants and Warrant Shares,
shall be computed solely on the basis of the proportion of such Shares, Warrants
and Warrant  Shares  that would be sold in such  Proposed  Transaction)  (a "Low
Return Transaction"), then, notwithstanding the provisions of Section 5.1 or 5.3
hereof,  Purchasers  shall  have the  right to make and  consummate  one or more
offers to the Company to acquire the Company in a merger  transaction  or to the
stockholders  to acquire all of their  shares of Common  Stock at a higher price
than the  price  being  offered  in such  Approved  Transaction  (with  non-cash
consideration valued at fair market value).

         5.5  Restrictions  on Amendments to the Rights Plan and Adoption of New
Rights Plan.  Until the Standstill  Termination  Date, the Board of Directors of
the Company shall not (a) amend the  definition of "Acquiring  Person" set forth
in the Rights  Plan (as  amended by the Rights  Amendment)  so as to deprive the
Gilbert Entities of the benefits afforded by the Rights Amendment, (b) adopt any
new rights  plan  pursuant  to which  holders  of rights  would be  entitled  to
purchase  securities upon the occurrence of certain  "triggering events" at less
than fair market value thereof  which adopts a definition of "Acquiring  Person"
(or any functionally equivalent designation) which deprives the Gilbert Entities
of the benefits afforded by the Rights Amendment or (c) cause any Gilbert Entity
to become, for the purposes of any application of the Rights Plan, an "Acquiring
Person" (or any functionally  equivalent designation) solely by reason of its or
his  purchase of any Voting  Securities  in  compliance  with  Section 5 of this
Agreement. If an event described in Section 6.10(a) occurs, the Company shall at
the same time amend the  definition of "Acquiring  Person" (or any  functionally
equivalent  designation)  to permit  the  Gilbert  Entities  to  acquire  Voting
Securities representing such greater Total Voting Power.

         5.6 Maintenance of Purchaser's Interest. From and after the date hereof
until the Standstill Termination Date, upon the issuance or sale for cash by the
Company of any Voting  Securities  (other than Voting Securities issued pursuant
to options or rights to acquire  Voting  Securities  granted or to be granted to
officers, employees,  consultants or directors pursuant to any stock plan, stock
bonus, stock appreciation  rights, stock purchase or other benefit plan relating
to such classes or persons,  hereafter  adopted by those members of the Board of
Directors who (i) in the case of officer and employee  awards,  are not officers
or  employees of the Company and (ii) in the case of all other  awards,  are not
entitled to  participate  in any plan then the  subject of  approval  other than
automatic  non-discretionary  plans), the Company shall offer to Purchasers,  by

<PAGE>

written notice to Purchasers given  concurrently with such issuance or sale, the
opportunity  to acquire such number of Voting  Securities  on the same terms and
conditions  as such  issuance  or sale as  shall  allow  the  Gilbert  Entities,
immediately following the issuance or sale of all such Voting Securities,  to be
the Beneficial Owner, in the aggregate,  of Voting  Securities  representing the
same Total Voting Power as that  represented by the Voting  Securities  owned by
the Gilbert  Entities  immediately  prior to the issuance or sale referred to in
this Section 5.6 (without giving effect to Section 5.1(ii)).

         5.7 Top Up Right.  From and after the date hereof until the  Standstill
Termination  Date, the Company  covenants that, so long as the Gilbert  Entities
Beneficially Own Voting Securities  representing 15% or more of the Total Voting
Power,  if the  Company  proposes  to  issue  Voting  Securities  or  securities
convertible  or  exchangeable  into Voting  Securities to any Person or group of
related  Persons (a "Buyer") and,  immediately  after such issuance,  such Buyer
would  Beneficially Own (a) capital stock  representing a greater  percentage of
the total capital stock outstanding (determined on an as-converted basis) or (b)
(after giving effect to Section 5.1(ii) with respect to the Gilbert Entities and
any  similar   restriction  with  respect  to  such  Buyer)  Voting   Securities
representing a greater  percentage of Total Voting Power, than the percentage of
total Common Stock outstanding or Total Voting Power, respectively, Beneficially
Owned by the Gilbert Entities at such time, then, notwithstanding the provisions
of Section 5.1(i),  the Company shall offer to Purchasers new Voting  Securities
(on the same terms and  conditions  as such  issuance to Buyer) and/or amend the
restrictions  set forth in Section 5.1(ii) so that,  after giving effect to such
issuances and/or  amendment,  Buyer and the Gilbert Entities would  Beneficially
Own (i) the same  number of shares of Common  Stock and (ii)  Voting  Securities
representing the same percentage of Total Voting Power (giving effect to Section
5.1(ii) as so amended  with  respect to the  Gilbert  Entities  and any  similar
restriction with respect to Buyer).

         5.8 Standstill  Termination  Events.  Notwithstanding the provisions of
Sections 5.1 and 5.3, if, in response to any tender or exchange offer to acquire
Voting Securities made pursuant to a Schedule 14D-1 filed with the Commission (a
"Tender Offer"), the Company (i) recommends acceptance of, or responds neutrally
to, such Tender Offer (as evidenced by the Company's  filing with the Commission
of a  Schedule  14D-9) or (ii)  redeems  the  Rights  issued  under  the  Rights
Agreement,  the  Gilbert  Entities  may make an offer to  purchase  for cash and
purchase  all  outstanding  shares of Common  Stock at a higher  price  than the
consideration being offered in the Tender Offer.

         6.  Definitions.  For purposes of this  Agreement,  the following terms
shall have the following meanings:

         6.1 "Affiliate" and "Associate" shall have the respective  meanings set
forth for such terms in Rule 12b-2 under the  Exchange  Act, as in effect on the
date of this Agreement.

         6.2 (a) The Gilbert Entities shall be deemed the "Beneficial Owner" of,
shall be deemed to  "Beneficially  Own" and shall be deemed to have  "Beneficial
Ownership" of:

                  (i) any  securities  which any  Purchaser or any other Gilbert
         Entity is deemed to  "beneficially  own"  within  the  meaning of Rules
         13d-3 and 13d-5  under the  Exchange  Act,  as in effect on the date of
         this Agreement; and

                  (ii) any securities (the  "underlying  securities")  which any
         Purchaser or any other Gilbert Entity has the right to acquire (whether
         such right is  exercisable  immediately  or only  after the  passage of
         time) pursuant to any agreement,  arrangement or understanding (written
         or oral), or upon the exercise of conversion  rights,  exchange rights,
         rights,  warrants or options,  or otherwise (it being  understood  that
         such Purchaser  shall also be deemed to be the Beneficial  Owner of the
         securities   convertible   into  or  exchangeable  for  the  underlying
         securities).


<PAGE>

         (b) Any  Person  other  than any  Gilbert  Entity  shall be deemed  the
"Beneficial Owner" of, shall be deemed to "Beneficially Own" and shall be deemed
to have  "Beneficial  Ownership" of any  securities  which such Person or any of
such Person's  Affiliates or Associates is deemed to  "beneficially  own" within
the meaning of Rules 13d-3 and 13d-5 under the Exchange Act, as in effect on the
date of this Agreement.

         6.3 "Change in Control" shall mean:

                  (a) the  acquisition,  other  than  from the  Company,  by any
         Person or group (within the meaning of Section  13(d)(3) or 14(d)(2) of
         the Exchange Act) of  Beneficial  Ownership of 50% or more of the Total
         Voting Power, but excluding,  for this purpose, any such acquisition by
         (i) the Company or any of its  subsidiaries,  (ii) any employee benefit
         plan (or related trust) of the Company or its subsidiaries or (iii) any
         corporation  with respect to which,  following such  acquisition,  more
         than  50%  of  the  combined  voting  power  of  the  then  outstanding
         securities  of  such  corporation  entitled  to vote  generally  in the
         election  of  directors  is  then  Beneficially   Owned,   directly  or
         indirectly,  by  Persons  who  were the  Beneficial  Owners  of  Voting
         Securities  of the Company  immediately  prior to such  acquisition  in
         substantially the same proportion as their ownership, immediately prior
         to such acquisition, of the Total Voting Power of the Company; or

                  (b)  individuals  who, as of October 1, 1995,  constitute  the
         Board of Directors of the Company (the "Incumbent Board") cease for any
         reason to constitute at least a majority of such Board; provided,  that
         any individual  becoming a director subsequent to October 1, 1995 whose
         election,  or nomination for election,  by the Company's  stockholders,
         was  approved  by a vote of at least a majority of the  directors  then
         comprising  the  Incumbent  Board  shall be  considered  as though such
         individual  were a member of the Incumbent  Board,  but excluding,  for
         this purpose, any such individual whose initial assumption of office is
         in connection with an actual or threatened election contest relating to
         the election of the directors of the Company (as such terms are used in
         Rule 14a-11 of Regulation 14A promulgated under the Exchange Act); or

                  (c)  approval  by  the   stockholders  of  the  Company  of  a
         reorganization,  merger or consolidation, in each case, with respect to
         which all or  substantially  all the  individuals and entities who were
         the respective  Beneficial Owners of the Voting Securities  immediately
         prior to such reorganization, merger or consolidation do not, following
         such  reorganization,   merger  or  consolidation,   Beneficially  Own,
         directly or indirectly,  more than 50% of the combined  voting power of
         the then outstanding  voting  securities  entitled to vote generally in
         the  election  of  directors  of the  corporation  resulting  from such
         reorganization, merger or consolidation; or

                  (d) the sale or other  disposition of all or substantially all
         the  assets of the  Company  in one  transaction  or series of  related
         transactions.


         6.4 "Code" shall mean the Internal Revenue Code of 1986, as amended.

         6.5 "Commission" shall mean the Securities and Exchange Commission.

         6.6 "ERISA" shall mean the Employee  Retirement  Income Security Act of
1974, as amended.

         6.7 "Exchange Act" shall mean the  Securities  Exchange Act of 1934, as
amended.

         6.8 "HSR Act" shall mean the Hart-Scott-Rodino  Antitrust  Improvements
Act of 1976, as amended.

         6.9 "Person"  shall mean any  individual,  partnership,  joint venture,
joint   stock   company,   association,   corporation,   trust,   unincorporated

<PAGE>

organization,  government  or  department  or agency of a  government,  or other
entity.

         6.10 A "Rights Plan Event"  shall mean (a) any  amendment of the Rights
Agreement  to change the  definition  of, or the  implementation  of a successor
rights plan which uses a definition of, "Acquiring  Person" (or any functionally
equivalent  designation)  to permit another Person to acquire Voting  Securities
representing  a  greater  percentage  of Total  Voting  Power  than the  maximum
percentage  of Total  Voting Power that the Gilbert  Entities  are  permitted to
Beneficially  Own  pursuant to Section  5.1(i)  hereof as then in effect (or, if
modified,  as  otherwise  in effect  under  this  Agreement)  or (b)  during the
pendency of a Tender  Offer (as defined in Section  5.8),  a court of  competent
jurisdiction   declares  the  Rights   Agreement  to  be  invalid  or  otherwise
inapplicable to the Tender Offer.

         6.11  "Securities  Act"  shall  mean the  Securities  Act of  1933,  as
amended.

         6.12  "Significant  Subsidiary"  shall mean a Subsidiary of the Company
constituting a "significant subsidiary" as defined in Rule 1-02(v) of Regulation
S-X promulgated by the Commission.

         6.13  "Subsidiary"  shall mean, as to any Person,  any  corporation  at
least a majority of the shares of stock of which  having  general  voting  power
under  ordinary  circumstances  to elect a majority of the Board of Directors of
such corporation  (irrespective of whether or not at the time stock of any other
class or  classes  shall  have or might  have  voting  power  by  reason  of the
happening of any contingency)  is, at the time as of which the  determination is
being made,  owned by such Person or one or more of its  Subsidiaries or by such
Person and one or more of its Subsidiaries.

         6.14  "13D  Group"  shall  mean any  group of  Persons  deemed  to be a
"person" within the meaning of Section  13(d)(3) of the Exchange Act which would
be  required  under  Section  13(d)  of the  Exchange  Act  and  the  rules  and
regulations thereunder (as in effect, and based on legal interpretations thereof
existing,  on the date  hereof) to file a  statement  on  Schedule  13D with the
Commission if such group Beneficially Owned Voting Securities  representing more
than 5% of any class of Voting Securities then outstanding.

         6.15  "Total  Voting  Power" at any time shall mean the total  combined
voting power in the general  election of directors of all the Voting  Securities
then  outstanding.  For purposes of  determining  the percentage of Total Voting
Power of Voting Securities Beneficially Owned:

                  (i) by the Gilbert  Entities,  any securities not  outstanding
         which are  subject  to  conversion  rights,  exchange  rights,  rights,
         warrants, options or similar securities held any Person shall be deemed
         to be  outstanding,  but shall not be deemed to be outstanding  for the
         purpose of computing the percentage of Voting  Securities  beneficially
         owned by any other  Person,  except that this  paragraph  (i) shall not
         apply to any determination made pursuant to Section 5.1(ii).

                  (ii) by any  Person  other  than  the  Gilbert  Entities,  any
         securities  not  outstanding  which are subject to  conversion  rights,
         exchange rights, rights, warrants,  options or similar rights which are
         convertible,  exchangeable  or  exercisable  within sixty days shall be
         deemed to be outstanding, but shall not be deemed to be outstanding for
         the  purpose  of  computing  the   percentage   of  Voting   Securities
         Beneficially Owned by any other Person.

         6.16 "Voting  Power" at any time shall mean the aggregate  voting power
in a general election of directors of Voting Securities.

         6.17 "Voting  Securities" shall mean at any time shares of any class of
capital stock of the Company  which are then  entitled to vote  generally in the
election of directors, including Common Stock.

         7. Miscellaneous

         7.1 Severability.  If any term,  provision,  covenant or restriction of
this Agreement is held by a court of competent  jurisdiction to be invalid, void
or  unenforceable,  the  remainder  of  the  terms,  provisions,  covenants  and
restrictions  of this Agreement  shall remain in full force and effect and shall
in no way be affected,  impaired or  invalidated.  It is hereby  stipulated  and
declared to be the  intention of the parties  that they would have  executed the
remaining terms, provisions, covenants and restrictions without including any of
such which may be hereafter declared invalid, void or unenforceable.


<PAGE>

         7.2 Specific  Enforcement.  Each  Purchaser,  on the one hand,  and the
Company, on the other, acknowledge and agree that irreparable damage would occur
in the event that any of the  provisions of this Agreement were not performed in
accordance  with  their  specific  terms  or  were  otherwise  breached.  It  is
accordingly  agreed that the  parties  shall be  entitled  to an  injunction  or
injunctions  to prevent  breaches of the  provisions  of this  Agreement  and to
enforce  specifically the terms and provisions hereof in any court of the United
States or any state thereof having  jurisdiction,  this being in addition to any
other remedy to which they may be entitled at law or equity.

         7.3 Entire Agreement. This Agreement (including the documents set forth
in the Exhibits  hereto)  contains the entire  understanding of the parties with
respect to the transactions contemplated hereby.

         7.4  Counterparts.  This  Agreement  may be  executed  in  one or  more
counterparts,  all of which shall be considered one and the same agreement,  and
shall become effective when one or more of the counterparts  have been signed by
each party and  delivered to the other  parties,  it being  understood  that all
parties need not sign the same counterpart.

         7.5 Notices. All notices, consents, requests,  instructions,  approvals
and other  communications  provided  for herein and all legal  process in regard
hereto  shall be validly  given,  made or served,  if in writing  and  delivered
personally,  by telecopy  (except for legal process) or sent by registered mail,
postage prepaid, if to:


                  The Company:

                  DIANON Systems, Inc.
                  200 Watson Boulevard
                  Stratford, Connecticut  06497
                  Attention:  Chairman, President and 
                                Chief Executive Officer
                  Telecopy No.:  (203) 381-4079

                  With a copy to:

                  Hughes Hubbard & Reed
                  One Battery Park Plaza
                  New York, New York  10004
                  Attention:  Ed Kaufmann
                  Telecopy No.: (212) 422-4726

                  Each Purchaser:

                  c/o Field Point Capital Management Company
                  104 Field Point Road
                  Greenwich, Connecticut  06830
                  Attention:  G.S. Beckwith Gilbert
                  Telecopy No.:  (203) 629-8757

                  With a copy to:

                  Weil, Gotshal & Manges
                  767 Fifth Avenue
                  New York, New York
                  Attention:  Dennis J. Block
                  Telecopy No.:  (212) 310-8007

or to such other  address or telex  number as any party may,  from time to time,
designate in a written notice given in a like manner. With respect to any notice
required hereunder to the Trust, the IRA or any other Gilbert Entity,  notice to
Mr. Gilbert shall be deemed to be effective notice to such Person.

<PAGE>

         7.6  Amendments.  This  Agreement may be amended as to  Purchasers  and
their  respective  successors,  and the  Company  may  take  any  action  herein
prohibited  or omit to perform any act  required to be  performed  by it, if the
Company shall obtain the written consent of Purchasers  and/or such  successors.
This Agreement may not be waived,  changed,  modified or discharged  orally, but
only by an  agreement  in writing  signed by the party or parties  against  whom
enforcement  of any waiver,  change,  modification  or discharge is sought or by
parties  with the right to  consent  to such  waiver,  change,  modification  or
discharge on behalf of such party.

         7.7 Cooperation.  Purchasers and the Company agree to take, or cause to
be taken,  all such further or other actions as shall reasonably be necessary to
make effective and consummate the transactions contemplated by this Agreement.

         7.8  Successors  and Assigns.  All covenants and  agreements  contained
herein  shall  bind and inure to the  benefit  of the  parties  hereto and their
respective successors.

         7.9  Indemnity.  (a) The Company  agrees to indemnify and save harmless
each Purchaser and each Purchaser's  officers,  directors and employees from and
against any and all costs, expenses, damages or other liabilities resulting from
any   misrepresentation   or  breach  of  a   representation   or   warranty  or
nonfulfillment of any covenant or agreement on the part of the Company under the
terms of this  Agreement  or any  legal,  administrative  or  other  proceedings
arising  out of the  execution  of this  Agreement  or the  consummation  of the
transactions  contemplated  hereby other than such costs,  expenses,  damages or
other  liabilities  resulting  from the  violation by any Purchaser of any legal
investment  laws  or  other  laws   restricting  or  governing  any  Purchaser's
investments generally,  from the violation or alleged violation by any Purchaser
of any duty such  Purchaser  may owe to any  Person  with a direct  or  indirect
interest in the Shares or the Warrant Shares.

         (b) Each indemnified party under this Section 7.9 will,  promptly after
the receipt of notice of the commencement of any action against such indemnified
party in respect of which indemnity may be sought from the Company on account of
any  indemnity  agreement  contained in this Section 7.9,  notify the Company in
writing of the commencement thereof. The omission of any indemnified party so to
notify the  Company of any such action  shall not  relieve the Company  from any
liability  which it may have to such  indemnified  party other than  pursuant to
this  Section  7.9 or,  unless the  Company  shall have been  prejudiced  by the
omission of such  indemnified  party so to notify the Company,  pursuant to this
Section  7.9. In case any such action shall be brought  against any  indemnified
party and it shall notify the Company of the commencement  thereof,  the Company
shall be entitled to participate therein and, to the extent that it may wish, to
assume  the  defense  thereof,  with  counsel  reasonably  satisfactory  to such
indemnified  party, and after notice from the Company to such indemnified  party
of its election so to assume the defense thereof, the Company will not be liable
to such indemnified  party under this Section 7.9 for any legal or other expense
subsequently  incurred by such indemnified  party in connection with the defense
thereof;  provided,  however,  that (i) if the Company shall elect not to assume
the defense of such claim or action or (ii) if the indemnified  party reasonably
determines (A) that there may be a conflict between the positions of the Company
and of the indemnified party in defending such claim or action or (B) that there
may be legal defenses  available to such indemnified  party different from or in
addition  to those  available  to the  Company,  then  separate  counsel for the
indemnified  party shall be entitled to  participate in and conduct the defense,
in the case of clauses (i) and (ii)(A), or such different defenses,  in the case
of clause (ii)(B),  and the Company shall be liable for any reasonable  legal or
other expenses incurred by the indemnified party in connection with the defense.

         7.10 Survival of Representations  and Warranties.  All  representations
and  warranties  contained  herein or made in writing by any party in connection
herewith  shall  survive the  execution  and delivery of this  Agreement and the
issuance  and  delivery  of the  Shares  and  the  Warrants,  regardless  of any
investigation made by or on behalf of any party.  Notwithstanding the foregoing,
the representations and warranties contained in this Agreement and the indemnity
obligations related to such  representations and warranties set forth in Section
7.9 shall  terminate  on, and no action or claim  with  respect  thereto  may be

<PAGE>

brought after,  the Standstill  Termination Date (except for any action or claim
which is pending on such date as evidenced by written  notice  thereof which has
been delivered to the appropriate party prior to such date).

         7.11 Transfer of Shares.  Purchasers  understand and agree that neither
any Shares,  the Warrants nor any Warrant Shares have been or will be registered
under the Securities  Act or the securities  laws of any state and that they may
be sold or  otherwise  disposed of only in one or more  transactions  registered
under the  Securities  Act and,  where  applicable,  such laws or as to which an
exemption from the  registration  requirements  of the Securities Act and, where
applicable,  such laws is  available.  Purchasers  acknowledge  that,  except as
provided  in the  Registration  Rights  Agreement,  Purchasers  have no right to
require the Company to register the Shares,  the Warrants or the Warrant Shares.
Purchasers  understand and agree that each certificate  representing the Shares,
the  Warrants or the  Warrant  Shares  (other  than,  with  respect to the first
legend,  the  Shares,  the  Warrants  or the  Warrant  Shares that are no longer
subject to the  provisions  of  Section 5 and other  than,  with  respect to the
second  legend,  the Shares,  the Warrants or the Warrant Shares which have been
transferred in a transaction  registered under the Securities Act or exempt from
the  registration  requirements  of the  Securities  Act  pursuant  to Rule  144
thereunder or any similar rule or regulation) shall bear the following legends:

                  "THE TRANSFER OF THE SECURITIES  REPRESENTED BY
         THIS  CERTIFICATE  IS RESTRICTED BY AN AGREEMENT ON FILE
         AT THE OFFICES OF THE CORPORATION."

                  "THE SECURITIES REPRESENTED BY THIS CERTIFICATE
         HAVE NOT BEEN  REGISTERED  UNDER THE  SECURITIES  ACT OF
         1933 OR THE SECURITIES  LAWS OF ANY STATE AND MAY NOT BE
         SOLD OR  OTHERWISE  DISPOSED  OF EXCEPT  PURSUANT  TO AN
         EFFECTIVE  REGISTRATION  STATEMENT  UNDER  SUCH  ACT AND
         APPLICABLE   STATE  SECURITIES  LAWS  OR  AN  APPLICABLE
         EXEMPTION TO THE  REGISTRATION  REQUIREMENTS OF SUCH ACT
         OR SUCH LAWS."

and Purchaser agrees to transfer the Shares, the Warrants and the Warrant Shares
only in accordance with the provisions of such legends.

         7.12 Governing  Law. This Agreement  shall be governed by and construed
and enforced in accordance with the laws of the State of Delaware.

         7.13 Expenses.  The Company shall, promptly after receiving appropriate
evidence thereof,  reimburse Purchasers for their costs and expenses (including,
without limitation,  reasonable attorneys' fees and expenses) in connection with
the negotiation of this Agreement and the other documents referred to herein and
the consummation of the transaction contemplated hereby and thereby.

         7.14 Publicity. The Company and Purchasers shall agree upon the text of
a press release announcing the transactions contemplated hereby.

         7.15 Required  Percentages.  Various rights of Purchasers  contained in
this  Agreement are  conditioned  upon the Gilbert  Entities  Beneficial  Owning
Voting Securities  representing a specified  percentage of Total Voting Power (a
"Required  Percentage").   Notwithstanding  such  provisions,   such  rights  of
Purchasers  shall  not  terminate  if the  Voting  Power  represented  by Voting
Securities  Beneficially  Owned by the Gilbert  Entities is reduced to less than
the  applicable  Required  Percentage  as a result of the issuance of any Voting
Securities by the Company unless, in connection with such issuance,  the Gilbert
Entities  have, and do not exercise,  the right to purchase their  proportionate
share of such  Voting  Securities  pursuant  to  Section  5.6;  provided,  that,
notwithstanding the immediately preceding provision,  such right shall terminate
if any Gilbert Entity sells or otherwise transfers  Beneficial  Ownership of any
Voting Securities such that, excluding the effects of all such Voting Securities
issuances  by the  Company,  the  Voting  Securities  Beneficially  Owned by the
Gilbert Entities represent less than the applicable Required Percentage.


<PAGE>

         IN WITNESS WHEREOF,  Purchaser, Mr. Gilbert and the Company have caused
this  Agreement  to be duly  executed,  all as of the day and year  first  above
written.


                                    GILBERT FAMILY TRUST

                                    By     /s/G.S. Beckwith Gilbert
                                           -----------------------------
                                    Name:    G. S. Beckwith Gilbert
                                    Title:   Trustee




                                      /s/G.S. Beckwith Gilbert
                                    -------------------------------
                                    G. S. Beckwith Gilbert


                                    G. S. BECKWITH GILBERT I.R.A.
                                        CONTRIBUTORY ACCOUNT

                                    By      /s/G.S. Beckwith Gilbert
                                           -----------------------------
                                    Name:    G. S. Beckwith Gilbert
                                    Title:   Trustee



                                    DIANON SYSTEMS, INC.

                                    By      /s/Richard A. Sandberg
                                           ----------------------------
                                    Name:    Richard A. Sandberg
                                    Title:   President, Chairman and Chief
                                             Executive Officer




                                                                   Exhibit 10.30


         REGISTRATION  RIGHTS  AGREEMENT,  dated as of  October  4,  1995  (this
"Agreement"), among DIANON Systems, Inc. a Delaware Corporation (the "Company'),
and the Gilbert Family Trust,  the G.S.  Beckwith  Gilbert  I.R.A.  Contributory
Account and G.S.  Beckwith  Gilbert  (collectively,  the "Investors" and each an
"Investor").  Certain  terms used herein are defined in Section 3 and terms used
but not  defined  herein  shall  have the  meaning  set  forth  in the  Purchase
Agreement (as defined below).

         1.  Background.  Pursuant  to a Stock and Warrant  Purchase  Agreement,
dated as of the date hereof (the  "Purchase  Agreement"),  among the Company and
the Investors, the Investors have purchased from the Company 1,000,000 shares of
the Company's Common Stock, par value $0.01 per share (the "Common Stock"),  and
two-year  warrants (the  "Warrant") to purchase  800,000  shares of Common Stock
(the "Warrant Shares").

         2. Registration Under Securities Act, etc.

         2.1  Registration  on  Request.  (a)  Request.  Subject to Section  2.9
hereof,  upon  the  written  request  of one or more  holders  (the  "Initiating
Holders')  of  Registrable  Securities  representing  not  less  than 30% of the
Registrable  Securities  that the  Company  effect  the  registration  under the
Securities Act of all of such Initiating Holders'  Registrable  Securities,  the
Company will promptly give written notice of such requested  registration to all
registered holders of Registrable Securities, and thereupon the Company will use
its best efforts to effect the registration  under the Securities Act, including
by means of a shelf  registration  pursuant to Rule 415 under the Securities Act
if so requested in such request and if the Company is then  eligible to use such
a registration, of

                  (i) the Registrable  Securities  which the Company has been so
         requested to register by such Initiating Holders, and

                  (ii) all other  Registrable  Securities  which the Company has
         been  requested to register by the holders  thereof by written  request
         given to the  Company  within 30 days after the giving of such  written
         notice  by the  Company  (such  holders  together  with the  Initiating
         Holders are hereinafter  referred to as the "Selling Holders"),  all to
         the extent  requisite  to permit  the  disposition  of the  Registrable
         Securities so to be registered.

         (b) Registration of Other Securities. Whenever the Company shall effect
a registration  pursuant to this Section 2.1 in connection  with an underwritten
offering by one or more Selling Holders of Registrable Securities, no securities
other than Registrable Securities shall be included among the securities covered
by such registration unless (i) the managing  underwriter of such offering shall
have advised each Selling Holder of Registrable Securities to be covered by such
registration  in writing that the inclusion of such other  securities  would not
adversely  affect such  offering  or (ii) the  Selling  Holders of not less than
66-2/3% of all Registrable  Securities to be covered by such registration  shall
have consented in writing to the inclusion of such other securities.

         (c) Registration  Statement Form.  Registrations under this Section 2.1
shall be on such  appropriate form of the Commission as shall be selected by the
Company and as shall be  reasonably  acceptable  to the Selling  Holders of more
than 50% of the Registrable  Securities so to be registered.  The Company agrees
to include in any such  registration  statement all  information  which,  in the
opinion of counsel to the Selling  Holders of  Registrable  Securities  so to be
registered and counsel to the Company, is required to be included.

         (d)  Expenses.  The  Company  will  pay the  Registration  Expenses  in
connection with any registration  requested pursuant to this Section 2.1. If the
Company,  at the request of holders of 66-2/3% of the Registrable  Securities to
be covered by such  registration,  withdraws the  registration  statement before
such registration statement becomes effective, the Selling Holders shall pay all
of the  Registration  Expenses  incurred in  connection  with such  registration
statement.


<PAGE>

         (e) Effective Registration Statement. A registration requested pursuant
to this  Section  2.1 shall not be deemed  to have been  effected  (i)  unless a
registration statement with respect thereto has become effective,  (ii) if after
it has become effective, such registration is interfered with by any stop order,
injunction or other order or requirement of the Commission or other governmental
agency or court for any reason not  attributable  to the Selling Holders and has
not thereafter become effective, or (iii) if the conditions to closing specified
in the purchase  agreement or underwriting  agreement,  if any,  entered into in
connection  with such  registration  are not satisfied or waived,  other than by
reason of a failure on the part of the Selling Holders.

         (f) Selection of Underwriters.  The underwriter or underwriters of each
underwritten offering of the Registrable Securities so to be registered shall be
selected by the Selling Holders of more than 50% of the  Registrable  Securities
so to be registered and shall be reasonably acceptable to the Company.

         (g) Priority in Requested Registration.  If the managing underwriter of
any  underwritten  offering  shall advise the Company in writing (with a copy to
each Selling Holder of Registrable Securities requesting  registration) that, in
its  opinion,  the  number  of  securities  requested  to be  included  in  such
registration by the holders of Registrable  Securities  exceeds the number which
can be sold in such  offering  within a price  range  acceptable  to the Selling
Holders of 66-2/3% of the  Registrable  Securities  requested  to be included in
such registration,  the Company will include in such registration, to the extent
of the number  which the  Company is so  advised  can be sold in such  offering,
Registrable  Securities requested to be included in such registration,  pro rata
among the  Selling  Holders on the basis of the  percentage  of the  Registrable
Securities of such Selling Holders requested so to be registered.  In connection
with any such  registration  to which  this  Section  2.1(g) is  applicable,  no
securities  other  than   Registrable   Securities  shall  be  covered  by  such
registration.

         (h) Limitations on Registration on Request. Notwithstanding anything in
this  Section 2.1 to the  contrary,  in no event will the Company be required to
effect, in the aggregate, without regard to the holder of Registrable Securities
making such request, more than two registrations pursuant to this Section 2.1.

         (i)  Withdrawal  of Request.  If holders of 66-2/3% of the  Registrable
Securities  to be covered by  registration  pursuant to this Section 2.1 request
the withdrawal of such registration after the filing thereof with the Commission
but prior to such  registration  becoming  effective the Company shall  withdraw
such registration.

         2.2.  Incidental   Registration.   (a)  Right  to  Include  Registrable
Securities.  If the  Company  at any time  after  the date  hereof  proposes  to
register any of its securities under the Securities Act by registration on Forms
S-1, S-2 or S-3 or any successor or similar  form(s)  (except  registrations  on
such  Forms  or  similar  form(s)  solely  for  registration  of  securities  in
connection  with a stock  option  or  other  employee  benefit  plans,  dividend
reinvestment plans, mergers,  acquisitions,  consolidations,  exchange offers or
subscription  offers),  whether or not for sale for its own account,  subject to
Section 2.9 hereof,  it will each such time give  prompt  written  notice to all
registered  holders of  Registrable  Securities of its intention to do so and of
such  holders'  rights under this Section 2.2.  Upon the written  request of any
such holder (a "Requesting  Holder") made as promptly as practicable  and in any
event  within 15 days after the  receipt of such  notice (7 days if the  Company
states in such  written  notice  or gives  telephonic  notice to all  registered
holders of Registrable Securities,  with written confirmation to follow promptly
thereafter, stating that (i) such registration will be on Form S-3 and (ii) such
shorter  period of time is required  because of a planned  filing  date)  (which
request shall specify the Registrable  Securities  intended to be disposed of by
such Requesting  Holder),  the Company will,  subject to Section 2.9 hereof, use
its best  efforts to effect the  registration  under the  Securities  Act of all
Registrable  Securities  which the Company has been so  requested to register by
the  Requesting  Holders  thereof;  provided,  that if, at any time after giving
written  notice of its  intention  to register any  securities  and prior to the
effective  date of the  registration  statement  filed in  connection  with such
registration,  the Company shall  determine for any reason not to register or to

<PAGE>

delay  registration of such securities,  the Company may, at its election,  give
written notice of such  determination  to each Requesting  Holder of Registrable
Securities  and the  Company  shall  (A) in the case of a  determination  not to
register,  be relieved of its obligation to register any Registrable  Securities
in connection with such registration (but not from any obligation of the Company
to pay the Registration  Expenses in connection  therewith),  without prejudice,
however,  to the  rights of any  holder or  holders  of  Registrable  Securities
entitled  to  do  so  to  request  that  such  registration  be  effected  as  a
registration  under Section 2.1, and (B) in the case of a determination to delay
registering,  be permitted to delay  registering any Registrable  Securities for
the  same  period  as  the  delay  in  registering  such  other  securities.  No
registration  effected  under this Section 2.2 shall  relieve the Company of its
obligation  to effect any  registration  upon  request  under  Section  2.1. The
Company will pay all  Registration  Expenses in connection with  registration of
Registrable Securities requested pursuant to this Section 2.2.

         (b) Priority in Incidental  Registrations.  If the managing underwriter
of any  underwritten  offering  shall inform the Company by letter of its belief
that the number or type of  Registrable  Securities  requested to be included in
such  registration  would materially  adversely  affect such offering,  then the
Company will include in such registration,  to the extent of the number and type
which the  Company  is so  advised  can be sold in (or  during the time of) such
offering,  first, all securities  proposed by the Company to be sold for its own
account,  second, such Registrable  Securities  requested to be included in such
registration  pro rata on the basis of the percentage of Registrable  Securities
of such Requesting  Holders requested so to be registered,  and third, any other
securities of the Company requested to be included in such registration pro rata
among the holders thereof based on the percentage of such securities held by the
holders thereof and requested so to be registered.

         2.3. Registration  Procedures.  If and whenever the Company is required
to use its best efforts to effect the registration of any Registrable Securities
under the  Securities Act as provided in Section 2.1 or 2.2, the Company will as
expeditiously as possible:

                  (a)  prepare  and  file  with  the  Commission  the  requisite
         registration  statement to effect such  registration and thereafter use
         its best  efforts to cause such  registration  statement to effect such
         registration  and  thereafter  use  its  best  efforts  to  cause  such
         registration statement to become effective; provided, however, that the
         Company may  discontinue any  registration of its securities  under the
         circumstances  specified  in  Section  2.2(a) at any time  prior to the
         effective date of the registration statement relating thereto;

                  (b) prepare and file with the Commission  such  amendments and
         supplements to such  registration  statement and the prospectus used in
         connection  therewith  as may be  necessary  to keep such  registration
         statement effective and to comply with the provisions of the Securities
         Act with  respect  to the  disposition  of all  Registrable  Securities
         covered  by such  registration  statement  for such  period as shall be
         required for the  disposition  of all of such  Registrable  Securities;
         provided,  that, except with respect to any such registration statement
         filed pursuant to Rule 415 under the  Securities  Act, such period need
         not exceed 120 days;

                  (c) furnish to each seller of Registrable  Securities  covered
         by such registration statement, such number of conformed copies of such
         registration  statement  and of  each  such  amendment  and  supplement
         thereto (in each case including all exhibits), such number of copies of
         the prospectus contained in such registration statement (including each
         preliminary  prospectus  and any  summary  prospectus)  and  any  other
         prospectus filed under Rule 424 under the Securities Act, in conformity
         with the  requirements of the Securities Act, and such other documents,
         as such seller may reasonably request;


<PAGE>

                  (d) use its  best  efforts  (i) to  register  or  qualify  all
         Registrable   Securities   and  other   securities   covered   by  such
         registration  statement under such other securities or blue sky laws of
         such States of the United  States of America  where an exemption is not
         available and as the sellers of Registrable  Securities covered by such
         registration  statement  shall  reasonably  request,  (ii) to keep such
         registration   or   qualification   in  effect  for  so  long  as  such
         registration  statement remains in effect,  and (iii) to take any other
         action  which may be  reasonably  necessary or advisable to enable such
         sellers to consummate  the  disposition  in such  jurisdictions  of the
         securities  to be sold by such  sellers,  except that the Company shall
         not for any  such  purpose  be  required  to  qualify  generally  to do
         business as a foreign corporation in any jurisdiction  wherein it would
         not but for the requirements of this subdivision (d) be obligated to be
         so  qualified  or to consent to general  service of process in any such
         jurisdiction;

                  (e) use its best efforts to cause all  Registrable  Securities
         covered  by  such  registration  statement  to be  registered  with  or
         approved  by such  other  Federal  or state  governmental  agencies  or
         authorities  as may be  necessary  in the  opinion  of  counsel  to the
         Company and counsel to the seller or sellers of Registrable  Securities
         to enable the seller or sellers  thereof to consummate the  disposition
         of such Registrable Securities;

                  (f) furnish to each seller of Registrable  Securities a signed
         counterpart  of (i) an opinion of  independent  counsel for the Company
         and  (ii)  a  "comfort"   letter  signed  by  the  independent   public
         accountants  who have  certified  the  Company's  financial  statements
         included or incorporated by reference in such  registration  statement,
         covering   substantially   the  same   matters  with  respect  to  such
         registration  statement (and the prospectus included therein),  and, in
         the case of the  accountants'  comfort  letter,  with respect to events
         subsequent to the date of such financial statements, as are customarily
         covered in  opinions of issuer's  counsel and in  accountants'  comfort
         letters delivered to the underwriters in underwritten  public offerings
         of securities  (and dated the dates such  opinions and comfort  letters
         are  customarily  dated) and, in the case of the  accountants'  comfort
         letters,  such other financial  matters,  and, in the case of the legal
         opinion,  such other legal matters,  as the sellers of more than 50% of
         the Registrable  Securities  covered by such registration  statement or
         the underwriters may reasonably request;

                  (g) notify each seller of  Registrable  Securities  covered by
         such  registration  statement  at any time when a  prospectus  relating
         thereto is required to be  delivered  under the  Securities  Act,  upon
         discovery  that,  or upon the  happening  of any  event as a result  of
         which, the prospectus included in such registration  statement, as then
         in effect,  includes an untrue statement of a material fact or omits to
         state any material fact  required to be stated  therein or necessary to
         make  the  statements  therein  not  misleading,  in the  light  of the
         circumstances  under  which they were made,  and at the  request of any
         such seller promptly  prepare and furnish to it a reasonable  number of
         copies of a supplement to or an amendment of such  prospectus as may be
         necessary so that,  as thereafter  delivered to the  purchasers of such
         securities,  such prospectus shall not include an untrue statement of a
         material  fact or omit to state a material  fact  required to be stated
         therein or necessary to make the  statements  therein not misleading in
         the light of the circumstances under which they were made;

                  (h)  otherwise  use  its  best  efforts  to  comply  with  all
         applicable rules and regulations of the Commission,  and make available
         to its security holders, as soon as reasonably practicable, an earnings
         statement  covering the period of at least twelve months,  but not more
         than eighteen  months,  beginning  with the first full  calendar  month
         after the effective date of such registration statement, which earnings
         statement  shall  satisfy  the  provisions  of  Section  11(a)  of  the

<PAGE>

         Securities Act, and promptly furnish to each such seller of Registrable
         Securities a copy of any amendment or  supplement to such  registration
         statement or prospectus;

                  (i) provide and cause to be  maintained  a transfer  agent and
         registrar (which, in each case, may be the Company) for all Registrable
         Securities covered by such registration statement from and after a date
         not later than the effective date of such registration; and

                  (j) use its best  efforts to list all  Registrable  Securities
         covered  by such  registration  statement  on any  national  securities
         exchange  on which  Registrable  Securities  of the same class and,  if
         applicable,  series,  covered by such  registration  statement are then
         listed.

The Company may require each seller of  Registrable  Securities  as to which any
registration is being effected to furnish the Company such information regarding
such seller and the distribution of such securities as the Company may from time
to time reasonably request in writing.

         Each holder of  Registrable  Securities  agrees by  acquisition of such
Registrable  Securities  that upon receipt of any notice from the Company of the
happening of any event of the kind described in subdivision  (g) of this Section
2.3,  such  holder will  forthwith  discontinue  such  holder's  disposition  of
Registrable  Securities pursuant to the registration  statement relating to such
Registrable  Securities  until  such  holder's  receipt  of  the  copies  of the
supplemented  or amended  prospectus  contemplated  by  subdivision  (g) of this
Section 2.3 and, if so directed by the Company,  will deliver to the Company (at
the Company's  expense) all copies,  other than permanent  file copies,  then in
such  holder's  possession  of  the  prospectus  relating  to  such  Registrable
Securities current at the time of receipt of such notice.

         2.4 Underwritten  Offerings.  (a) Requested Underwritten  Offerings. If
requested  by the  underwriters  for any  underwritten  offering  by  holders of
Registrable  Securities pursuant to a registration  requested under Section 2.1,
the Company will enter into an underwriting agreement with such underwriters for
such  offering,  such agreement to be reasonably  satisfactory  in substance and
form to the Company,  each such holder and the  underwriters and to contain such
representations  and  warranties  by the  Company  and such  other  terms as are
generally prevailing in agreements of that type, including,  without limitation,
indemnities to the effect and to the extent provided in Section 2.7. The holders
of the Registrable  Securities  proposed to be distributed by such  underwriters
will  cooperate  with  the  Company  in  the  negotiation  of  the  underwriting
agreement.  Such  holders  of  Registrable  Securities  shall be parties to such
underwriting  agreement and may, at their option, require that any or all of the
representations  and warranties by, and the other agreements on the part of, the
Company to and for the  benefit of such  underwriters  shall also be made to and
for the benefit of such holders of Registrable Securities and that any or all of
the  conditions  precedent to the  obligations of such  underwriters  under such
underwriting  agreement  on  conditions  precedent  to the  obligations  of such
holders of Registrable  Securities.  Any such holder of  Registrable  Securities
shall not be required to make any representations or warranties to or agreements
with the Company other than representations,  warranties or agreements regarding
such holder,  such holder's  Registrable  Securities and such holder's  intended
method of distribution and any other representation required by law.

         (b)  Incidental  Underwritten  Offerings.  If the  Company  proposes to
register any of its  securities  under the  Securities  Act as  contemplated  by
Section 2.2 and such  securities are to be distributed by or through one or more
underwriters,  the  Company  will,  subject to Sections  2.2 and 2.9 hereof,  if
requested  by any  Requesting  Holder  of  Registrable  Securities  use its best
efforts  to  arrange  for  such  underwriters  to  include  all the  Registrable
Securities to be offered and sold by such Requesting Holder among the securities
of  the  Company  to  be  distributed  by  such  underwriters.  The  holders  of
Registrable  Securities to be distributed by such underwriters  shall be parties
to the underwriting agreement between the Company and such underwriters and may,
at their option,  require that any or all of the  representations and warranties
by, and the other  agreements on the part of, the Company to and for the benefit

<PAGE>

of such  underwriters  shall also be made to and for the benefit of such holders
of Registrable Securities and that any or all of the conditions precedent to the
obligations of such underwriters under such underwriting agreement be conditions
precedent to the obligations of such holders of Registrable Securities. Any such
Requesting  Holder of Registrable  Securities  shall not be required to make any
representations  or  warranties  to  or  agreements  with  the  Company  or  the
underwriters other than representations, warranties or agreements regarding such
Requesting  Holder,  such Requesting  Holder's  Registrable  Securities and such
Requesting  Holder's intended method of distribution or as otherwise required by
law.

         2.5.  Preparation;  Reasonable  Investigation.  In connection  with the
preparation and filing of each  registration  statement under the Securities Act
pursuant  to this  Agreement  the Company  will give the holders of  Registrable
Securities registered under such registration statement, their underwriters,  if
any, and their respective counsel and accountants the opportunity to participate
in the preparation of such  registration  statements,  each prospectus  included
therein or filed with the  Commission,  and,  to the  extent  practicable,  each
amendment  thereof or supplement  thereto,  and give each of them such access to
its books and records (to the extent  customarily  given to the  underwriters of
the Company's  securities),  such  opportunities  to discuss the business of the
Company  with its  officers  and the  independent  public  accountants  who have
certified its financial statements as shall be necessary, in the opinion of such
holders'  and such  underwriters'  respective  counsel,  to conduct a reasonable
investigation within the meaning of the Securities Act.

         2.6.  Limitations,  Conditions and  Qualifications to Obligations under
Registration  Covenants.  The  obligations  of the Company to use its reasonable
efforts  to  cause  the  Registrable  Securities  to  be  registered  under  the
Securities Act are subject to each of the following limitations,  conditions and
qualifications:

         (a)  The  Company  shall  not be  obligated  to file  any  registration
statement  pursuant to Section  2.1 hereof at any time if the  Company  would be
required to include financial  statements  audited as of any date other than the
end of its fiscal year.

         (b) The Company  shall be entitled to postpone for a reasonable  period
of time (but not  exceeding  60 days) the filing of any  registration  statement
otherwise required to be prepared and filed by it pursuant to Section 2.1 if the
Company  determines,  in its reasonable  judgment,  that such  registration  and
offering   would   interfere   with  any   financing,   acquisition,   corporate
reorganization or other material transaction involving the Company or any of its
Affiliates or would require premature  disclosure thereof and promptly gives the
holders of Registrable  Securities  requesting  registration thereof pursuant to
Section 2.1 written notice of such determination, containing a general statement
of the reasons for such  postponement  and an  approximation  of the anticipated
delay. If the Company shall so postpone the filing of a registration  statement,
such holders of Registrable Securities requesting  registration thereof pursuant
to Section 2.1 shall have the right to withdraw the request for  registration by
giving  written notice to the Company within 30 days after receipt of the notice
of postponement and, in the event of such withdrawal,  such request shall not be
counted for  purposes  of the  requests  for  registration  to which  holders of
Registrable Securities are entitled pursuant to Section 2.1 hereof.

         (c) (i)  Holders of  Registrable  Securities  shall use all  reasonable
efforts  to effect as wide a  distribution  of such  Registrable  Securities  as
reasonably  practicable  (and the holders of such  Registrable  Securities shall
secure the  agreement of their  underwriter  or  underwriters,  if any, for such
offering  to  comply  with the  foregoing),  and (ii)  except  with  respect  to
underwritten  offerings pursuant hereto, holders of Registrable Securities shall
use  their  best  efforts  (which  shall  include  advising  any  broker  of the
provisions of this Section 2.6(c) but shall not require undue  investigation  on
the part of any such  holder) so that in no event shall any sale of  Registrable
Securities be made  knowingly to any Person  (including  its  Affiliates) or any
Person  or  entities  which  are to the  knowledge  of such  holders  (or to the
knowledge  of any  underwriter  for such  holders)  part of any 13D Group  which

<PAGE>

includes such  purchaser or any of its  Affiliates),  that, in each case,  after
giving  effect  to  such  sale,  would   Beneficially   Own  Voting   Securities
representing more than 10% of the Total Voting Power.

         2.7. Indemnification.  (a) Indemnification by the Company. In the event
of any  registration  of any securities of the Company under the Securities Act,
the Company will, and hereby does,  indemnify and hold harmless,  in the case of
any registration  statement filed pursuant to Section 2.1 or 2.2, each seller of
any  Registrable  Securities  covered  by  such  registration   statement,   its
directors,  officers,  partners, agents and affiliates and each other Person who
participates  as an underwriter  in the offering or sale of such  securities and
each other  Person,  if any,  who controls  such seller or any such  underwriter
within the meaning of the Securities Act, against any losses, claims, damages or
liabilities,  joint or  several,  to which  such  seller  or any such  director,
officer,  partner,  agent or affiliate or underwriter or controlling  Person may
become  subject under the  Securities  Act or otherwise  insofar as such losses,
claims, damages or liabilities (or actions or proceedings,  whether commenced or
threatened,  in  respect  thereof)  arise  out of or are based  upon any  untrue
statement or alleged  untrue  statement of any  material  fact  contained in any
registration  statement under which such  securities  were registered  under the
Securities  Act,  any  preliminary  prospectus,   final  prospectus  or  summary
prospectus  contained therein,  or any amendment or supplement  thereto,  or any
omission or alleged  omission to state  therein a material  fact  required to be
stated  therein  or  necessary  to make the  statements  therein in light of the
circumstances  in which  they were made not  misleading,  and the  Company  will
reimburse  such  seller  and each  such  director,  officer,  partner,  agent or
affiliate,  underwriter  and  controlling  Person  for any  legal  or any  other
expenses  reasonably  incurred  by  them in  connection  with  investigating  or
defending any such loss, claim, liability, action or proceeding;  provided, that
the  Company  shall not be liable in any such case to the  extent  that any such
loss, claim,  damage,  liability (or action or proceeding in respect thereof) or
expense  arises out of or is based upon an untrue  statement  or alleged  untrue
statement or omission or alleged omission made in such  registration  statement,
any such preliminary prospectus, final prospectus, summary prospectus, amendment
or  supplement  in reliance  upon and in  conformity  with  written  information
furnished to the Company  through an instrument duly executed by or on behalf of
such seller or underwriter,  as the case may be, specifically stating that it is
for use in the preparation  thereof;  and, provided,  further,  that the Company
shall not be liable to any  Person who  participates  as an  underwriter  in the
offering or sale of  Registrable  Securities  or any other  Person,  if any, who
controls such underwriter  within the meaning of the Securities Act, in any such
case to the extent that any such loss,  claim,  damage,  liability (or action or
proceeding in respect  thereof) or expenses arises out of such Person's  failure
to  send  or  give a copy  of the  final  prospectus,  as the  same  may be then
supplemented or amended,  to the Person asserting an untrue statement or alleged
untrue  statement  or  omission  or alleged  omission at or prior to the written
confirmation  of the  sale of  Registrable  Securities  to such  Person  if such
statement or omission  was  corrected in the final  prospectus.  Such  indemnity
shall remain in full force and effect regardless of any investigation made by or
on  behalf of such  seller  or any such  director,  officer,  partner,  agent or
affiliate  or  controlling  person  and  shall  survive  the  transfer  of  such
securities by such seller.

         (b)  Indemnification  by the Sellers.  As a condition to including  any
Registrable  Securities in any  registration  statement,  the Company shall have
received an undertaking  satisfactory to it from the prospective  seller of such
Registrable  Securities,  to indemnify and hold harmless (in the same manner and
to the same  extent as set forth in  subdivision  (a) of this  Section  2.7) the
Company, and each director of the Company,  each officer of the Company and each
other  Person,  if any,  who  controls  the  Company  within the  meaning of the
Securities  Act,  with  respect  to any  statement  or alleged  statement  in or
omission or alleged omission from such registration  statement,  any preliminary
prospectus,  final prospectus or summary prospectus  contained  therein,  or any
amendment or  supplement  thereto,  if such  statement  or alleged  statement or
omission or alleged  omission was made in reliance upon and in  conformity  with
written information furnished to the Company through an instrument duly executed
by such seller  specifically  stating that it is for use in the  preparation  of

<PAGE>

such registration statement,  preliminary prospectus, final prospectus,  summary
prospectus,  amendment or supplement.  Such indemnity shall remain in full force
and effect,  regardless of any investigation made by or on behalf of the Company
or any such  director,  officer  or  controlling  person and shall  survive  the
transfer of such securities by such seller.

         (c) Notices of Claims,  etc.  Promptly  after receipt by an indemnified
party or notice of the  commencement  of any action or  proceeding  involving  a
claim  referred to in the  preceding  subdivisions  of this  Section  2.7,  such
indemnified  party will, if a claim in respect  thereof is to be made against an
indemnifying  party,  give written notice to the latter of the  commencement  of
such action;  provided, that the failure of any indemnified party to give notice
as provided herein shall not relieve the  indemnifying  party of its obligations
under the preceding  subdivisions of this Section 2.7, except to the extent that
the indemnifying party is actually materially prejudiced by such failure to give
notice.  In case any such  action is brought  against an  indemnified  party the
indemnifying  party  shall be  entitled to  participate  in and,  unless in such
indemnified  party's  reasonable  judgment a conflict of interest  between  such
indemnified  and  indemnifying  parties may exist in respect of such  claim,  to
assume the defense thereof,  jointly with any other indemnifying party similarly
notified to the extent that it may wish, with counsel reasonably satisfactory to
such indemnified  party,  and after notice from the  indemnifying  party to such
indemnified  party  of its  election  so to  assume  the  defense  thereof,  the
indemnifying  party shall not be liable to such indemnified  party for any legal
or other  expenses  subsequently  incurred by the latter in connection  with the
defense thereof other than reasonable costs of investigation; provided, however,
that all  indemnified  parties  with  respect to a claim shall have the right to
employ one  separate  counsel in  connection  with  their  participation  in the
defense of such claim and the fees and expenses of such counsel shall be paid by
the  indemnifying  party if,  but only if, in the  reasonable  judgment  of such
indemnified  parties,  based upon the written  advice of counsel,  a conflict of
interest exists between such indemnified parties and the indemnifying party with
respect to such claim. An  indemnifying  party who does not elect to participate
in the defense of a claim, together with all other indemnifying  parties,  shall
not be  obligated  to pay the fees and expenses of more than one counsel for all
indemnified  parties with respect to any such claim. No indemnifying party shall
be liable for any  settlement of any action or proceeding  effected  without its
written  consent.  No  indemnifying  party  shall,  without  the  consent of the
indemnified party, consent to entry of any judgment or enter into any settlement
which  does not  include  as an  unconditional  term  thereof  the giving by the
claimant or plaintiff to such indemnified  party of a release from all liability
in respect to such claim or litigation.

         (d) Contribution.  If the indemnification  provided for in this Section
2.7 shall for any reason be held by a court to be  unavailable to an indemnified
party under subparagraph (a) or (b) hereof in respect of any loss, claim, damage
or liability, or any action in respect thereof, then, in lieu of the amount paid
or payable under  subparagraph (a) or (b) hereof,  the indemnified party and the
indemnifying  party under subparagraph (a) or (b) hereof shall contribute to the
aggregate  losses,  claims,  damages and liabilities  (including  legal or other
expenses  reasonably incurred in connection with investigating the same), (i) in
such  proportion as is  appropriate to reflect the relative fault of the Company
and  the  prospective   sellers  of  Registrable   Securities   covered  by  the
registration  statement which resulted in such loss, claim, damage or liability,
or action in respect thereof,  with respect to the statements or omissions which
resulted in such loss, claim, damage or liability, or action in respect thereof,
as well as any other relevant equitable considerations or (ii) if the allocation
provided  by clause  (i)  above is not  permitted  by  applicable  law,  in such
proportion as shall be appropriate to reflect the relative  benefits received by
the Company and such  prospective  sellers from the  offering of the  securities
covered  by  such  registration   statement.  No  Person  guilty  of  fraudulent
misrepresentation  (within the meaning of Section 11(f) of the  Securities  Act)
shall be  entitled  to  contribution  from any Person who was not guilty of such
fraudulent   misrepresentation.   Such  prospective   sellers'   obligations  to
contribute as provided in this subparagraph (d) are several in proportion to the
relative  value of  their  respective  Registrable  Securities  covered  by such
registration  statement and not joint. In addition, no Person shall be obligated

<PAGE>

to contribute  hereunder any amounts in payment for any settlement of any action
or claim  effected  without such  Person's  consent,  which consent shall not be
unreasonably withheld.

         (e) Other Indemnification.  Indemnification and contribution similar to
that  specified  in the  preceding  subparagraphs  of  this  Section  2.7  (with
appropriate  modifications)  shall be given by the  Company  and each  seller of
Registrable  Securities  with  respect  to any  required  registration  or other
qualification  of securities under any Federal or state law or regulation of any
governmental authority other than the Securities Act.

         (f)  Indemnification  Payments.  The  indemnification  and contribution
required by this  Section  2.7 shall be made by periodic  payments of the amount
thereof during the course of the investigation or defense, as and when bills are
received or expense, loss, damage or liability is incurred.

         2.8. Adjustment Affecting Registrable Securities.  The Company will not
effect  or  permit  to occur  any  combination  or  subdivision  of  Registrable
Securities which would materially adversely affect the ability of the holders of
Registrable   Securities   to  include  such   Registrable   Securities  in  any
registration   of  its  securities   contemplated  by  this  Section  2  or  the
marketability of such Registrable Securities under any such registration.

         2.9.   Conditions  and  Limitations  on  Registrations  of  Registrable
Securities.  (a) The Company shall not be required to effect any registration of
Registrable Securities pursuant to this Section 2 until after October 4, 1997 or
at any time that all Registrable  Securities held by any holders requesting such
registration  can be  transferred  by such  holders  under  Rule 144  under  the
Securities Act within 183 days from the date of such request for registration.

         (b) The Company  shall not be required  to effect any  registration  of
Registrable Securities pursuant to Section 2.2 hereof if it shall deliver to the
holder or holders  requesting  such  registration  an opinion of counsel  (which
opinion and counsel shall be reasonably  satisfactory to such holder or holders)
to the effect that the Registrable  Securities requested to be registered may be
sold by such  holder in the  manner,  time  period and volume  intended  by such
holder without registration under the Securities Act.

         (c) The registration  rights provided by this Section 2 shall terminate
upon the tenth anniversary of the date hereof.

         2.10.  Certain  Rights  of  an  Investor  If  Named  in a  Registration
Statement.  If any statement  contained in a  registration  statement  under the
Securities  Act refers to an Investor by name or  otherwise as the holder of any
securities of the Company,  then such  Investor  shall have the right to require
(i) the  insertion  therein  of  language,  in  form  and  substance  reasonably
satisfactory to such Investor and the Company, to the effect that the holding by
such  Investor of such  securities  does not  necessarily  make such  Investor a
"controlling person" of the Company within the meaning of the Securities Act and
is not to be construed as a  recommendation  by such Investor of the  investment
quality of the Company's debt or equity securities covered thereby and that such
holding  does not imply that such  Investor  will  assist in meeting  any future
financial  requirements  of the Company or (ii) in the event that such reference
to such Investor by name or otherwise is not required by the  Securities  Act or
any of the rules and  regulations  promulgated  thereunder,  the deletion of the
reference to such Investor.

         3. Definitions.  As used herein, unless the context otherwise requires,
the following terms have the following respective meanings:

         "Commission" means the Securities and Exchange  Commission or any other
Federal agency at the time administering the Securities Act.

         "Exchange Act" means the  Securities  Exchange Act of 1934, as amended,
or any similar Federal statute,  and the rules and regulations of the Commission
thereunder,  all as the same  shall be in  effect at the  time.  Reference  to a
particular  section of the  Securities  Exchange Act of 1934, as amended,  shall
include a reference  to the  comparable  section,  if any,  of any such  similar
Federal statute.


<PAGE>

         "Person"  means  a  corporation,  an  association,  a  partnership,  an
unincorporated organization, a joint venture, a joint stock company, a trust, an
individual,  a government or a department  or agency of a  government,  or other
entity.

         "Registrable  Securities"  means (i) the Shares and the Warrant  Shares
held  from  time  to time by the  Investors  or any  Person  to  whom  any  such
securities  have been  transferred  in  accordance  with  Section  5.2(c) of the
Purchase Agreement  ("Permitted Holders") and (ii) any securities of the Company
(including,  without limitation,  the Rights) issued or issuable with respect to
any  shares  of Common  Stock by way of a stock  dividend  or stock  split or in
connection with a combination of shares, recapitalization, merger, consolidation
or  other  reorganization  or  otherwise.   As  to  any  particular  Registrable
Securities, once issued such securities shall cease to be Registrable Securities
when (a) a registration  statement  with respect to the sale of such  securities
shall have become  effective under the Securities Act and such securities  shall
have been disposed of in accordance with such registration  statement,  (b) they
shall have been sold as permitted by Rule 144 (or any successor provision) under
the  Securities  Act,  (c) they  shall  have  been  otherwise  transferred,  new
certificates  for them not bearing a legend  restricting  further transfer shall
have been delivered by the Company and subsequent  public  distribution  of them
shall not require  registration  of them under the  Securities  Act, or (d) they
shall have ceased to be outstanding.

         "Registration  Expenses"  means all expenses  incident to the Company's
performance of or compliance with Section 2, including,  without limitation, all
registration,  filing and NASD fees,  all fees and  expenses of  complying  with
securities  or blue sky laws,  all word  processing,  duplicating  and  printing
expenses, messenger and delivery expenses, the fees and disbursements of counsel
for  the  Company  and of its  independent  public  accountants,  including  the
expenses of "cold comfort"  letters  required by or incident to such performance
and compliance,  any fees and disbursements of underwriters  customarily paid by
issuers or sellers of securities and, in the case of a registration  pursuant to
Sections 2.1 and 2.2, the reasonable  fees and expenses of one counsel to all of
the Selling Holders  (selected by Selling  Holders  representing at least 50% of
the Registrable  Securities covered by such  registration);  provided,  however,
that  Registration  Expenses  shall  exclude and the sellers of the  Registrable
Securities  shall pay the fees and  disbursements  of counsel and accountants to
such sellers and  underwriting  discounts and  commissions and transfer taxes in
respect of the Registrable Securities being registered,  except that in the case
of a  registration  pursuant to Sections 2.1 and 2.2, the Company  shall pay the
reasonable fees and expenses of one counsel to the Selling Holders  (selected by
Selling Holders representing at least 50% of the Registrable  Securities covered
by such registration).

         "Securities  Act" means the Securities Act of 1933, as amended,  or any
similar  Federal  statute,  and  the  rules  and  regulation  of the  Commission
thereunder,  all as the same  shall be in effect at the  time.  References  to a
particular  section of the  Securities  Act of 1933 shall include a reference to
the comparable section, if any, of any such similar Federal statute.

         4. Rule 144. The Company shall take all actions reasonably necessary to
enable  holders  of  Registrable  Securities  to sell  such  Securities  without
registration  under the  Securities  Act within the limitation of the exemptions
provided by (a) Rule 144 under the  Securities  Act, as such Rule may be amended
from time to time,  or (b) any similar rule or regulation  hereafter  adopted by
the  Commission  including,  without  limiting the  generality of the foregoing,
filing on a timely basis all reports  required to be filed by the Exchange  Act.
Upon the  request of any holder of  Registrable  Securities,  the  Company  will
deliver to such holder a written  statement as to whether it has  complied  with
such requirements.


<PAGE>

         5. Amendments and Waivers.  This Agreement may be amended only with the
written  consent of the  Company  and the  Company  may take any  action  herein
prohibited,  or omit to perform any act herein  required to be  performed by it,
only if the Company shall have obtained the written  consent to such  amendment,
action or omission  to act, of the holder or holders of at least  66-2/3% of the
Registrable Securities. Each holder of any Registrable Securities at the time or
thereafter  outstanding shall be bound by any consent authorized by this Section
5, whether or not such Registrable Securities shall have been marked to indicate
such consent.

         6. Nominees for Beneficial  Owners.  In the event that any  Registrable
Securities  are  held  by a  nominee  for  the  beneficial  owner  thereof,  the
beneficial  owner  thereof  may,  at its  election in writing  delivered  to the
Company, be treated as the holder of such Registrable Securities for purposes of
any request or other action by any holder or holders of  Registrable  Securities
pursuant to this Agreement or any  determination  of any number or percentage of
shares or  Registrable  Securities  held by any holder or holders of Registrable
Securities  contemplated  by this  Agreement.  If the  beneficial  owner  of any
Registrable  Securities so elects, the Company may require assurances reasonably
satisfactory  to it of such owner's  beneficial  ownership  of such  Registrable
Securities.

         7. Notices. All communications  provided for hereunder shall be sent by
postage-prepaid  first-class  mail,  shall be deemed to be  received  three days
after  being  sent,  or, if earlier,  the date of actual  receipt,  and shall be
addressed as follows:

         (a) if to any  Investor,  addressed to such  Investor in the manner set
forth in the Purchase Agreement, or at such other address as such Investor shall
have furnished to the Company in writing;

         (b) if to any other holder of  Registrable  Securities,  at the address
that such holder shall have  furnished to the Company in writing,  or, until any
such other  holder so  furnishes  to the Company an address,  then to and at the
address of the last holder of such  Registrable  Securities who has furnished an
address to the Company; or

         (c) if to the  Company,  addressed to it in the manner set forth in the
Purchase Agreement, or at such other address as the Company shall have furnished
to each holder of Registrable Securities at the time outstanding.

         8.  Assignment;  Calculation  of  Percentage  Interests in  Registrable
Securities. (a) This Agreement shall be binding upon and inure to the benefit of
and be enforceable  by the parties hereto and, with respect to the Company,  its
respective successors and assigns and, with respect to the Investors, any holder
of any Registrable Securities,  subject to the provisions respecting the minimum
numbers of percentages of shares of Registrable  Securities required in order to
be entitled to certain rights, or take certain actions,  contained  herein.  The
Investors  named in the first  paragraph  of this  Agreement  (and not any other
holder of  Registrable  Securities or any other  Person) shall be permitted,  in
connection with a transfer or disposition of Registrable Securities permitted by
the Purchase  Agreement,  to impose  conditions or constraints on the ability of
the transferee, as a holder of Registrable Securities, to request a registration
pursuant  to Section  2.1 and shall  provide  the  Company  with  copies of such
conditions or constraints and the identity of such transferees.

         (b) For the purposes of this Agreement,  all references to a percentage
of the  Registrable  Securities  shall be  calculated  based  upon the number of
shares of Registrable  Securities  outstanding  at the time such  calculation is
made assuming the issuance of all Warrant Shares.

         9. Descriptive  Headings.  The descriptive headings of the sections and
paragraphs of this Agreement are inserted for reference only and shall not limit
or otherwise affect the meaning hereof.

         10.  Governing Law. This  Agreement  shall be construed and enforced in
accordance with, and the rights of the parties shall be governed by, the laws of
the State of Delaware.


<PAGE>

         11.  Counterparts.  This  Agreement  may be  executed  in any number of
counterparts,  each  of  which  shall  be  deemed  an  original,  but  all  such
counterparts shall together constitute one and the same instrument.

         IN WITNESS  THEREOF,  the  parties  have caused  this  Agreement  to be
executed and delivered by their respective officers thereunto duly authorized as
of the date first above written.


                                   /s/  G.S. Beckwith Gilbert
                                  --------------------------
                                   G.S. Beckwith Gilbert



                                   GILBERT FAMILY TRUST


                                   By  /s/ G. S. Beckwith Gilbert
                                      ------------------------------
                                       Name: G. S. Beckwith Gilbert
                                       Title:Trustee



                                   G.S. BECKWITH GILBERT I.R.A. CONTRIBUTORY
                                   ACCOUNT


                                   By /s/ G. S. Beckwith Gilbert
                                     -----------------------------
                                       Name:  G.S. Beckwith Gilbert
                                       Title:Trustee



                                   DIANON SYSTEMS, INC.


                                   By  /s/ Richard A. Sandberg
                                     ---------------------------
                                       Name: Richard A. Sandberg
                                       Title:President, Chairman and
                                             Chief Executive Officer






                                                                   Exhibit 10.31

                                                               WARRANT NO. W-1

THE TRANSFER OF THE SECURITIES  REPRESENTED BY THIS CERTIFICATE IS RESTRICTED BY
AN AGREEMENT ON FILE AT THE OFFICES OF THE CORPORATION.

THE SECURITIES  REPRESENTED BY THIS  CERTIFICATE  HAVE NOT BEEN REGISTERED UNDER
THE SECURITIES  ACT OF 1933 OR THE  SECURITIES  LAWS OF ANY STATE AND MAY NOT BE
SOLD OR  OTHERWISE  DISPOSED  OF EXCEPT  PURSUANT TO AN  EFFECTIVE  REGISTRATION
STATEMENT UNDER SUCH ACT AND APPLICABLE  STATE  SECURITIES LAWS OR AN APPLICABLE
EXEMPTION TO THE REGISTRATION REQUIREMENTS OF SUCH ACT OR SUCH LAWS.

                               WARRANT CERTIFICATE

                       TO PURCHASE SHARES OF COMMON STOCK,
                          PAR VALUE $0.01 PER SHARE, OF
                              DIANON SYSTEMS, INC.

                     Exercisable commencing October 5, 1995:
         Void after 5:00 p.m., New York City time, on October 4, 1997.

     THIS  CERTIFIES  that,  for value  received,  G. S.  Beckwith  Gilbert,  or
registered assigns, is the owner of 800,000 Warrants (as defined below), each of
which,  upon the exercise  thereof,  entitles the  registered  holder thereof to
purchase from DIANON Systems,  Inc., a Delaware corporation (the "Corporation"),
and requires the  Corporation  to issue,  one fully paid,  duly  authorized  and
nonassessable share (the "Number Issuable") of Common Stock, par value $0.01 per
share, of the Corporation (the "Common Stock"),  at any time commencing  October
5, 1995, and continuing up to 5:00 p.m., New York City time, on October 4, 1997,
at an exercise price of $6.00 (the "Exercise Price"),  subject to the conditions
hereinafter set forth. The Number Issuable and the Exercise Price are subject to
adjustment  from time to time pursuant to the  provisions of Sections 1 and 2 of
this Warrant  Certificate.  The Warrants  evidenced by this  Certificate are the
two-year  warrants  to  purchase  up to  800,000  shares  of Common  Stock  (the
"Warrants")  issued pursuant to a Stock and Warrant Purchase  Agreement dated as
of October 4, 1995 among the Gilbert  Family Trust,  the G.S.  Beckwith  Gilbert
I.R.A.  Contributory  Account,  G.S.  Beckwith  Gilbert and the Corporation (the
"Purchase Agreement").

     1.  Subject to the last two  paragraphs  of this  Section  1, the  Warrants
evidenced hereby may be exercised by the registered holder hereof at any time on
or before  5:00 p.m.,  New York City time,  on October 4, 1997 (the  "Expiration
Date"),  upon (a) surrender to the  Corporation  at the principal  office of the
Corporation in the State of Connecticut (the "Transfer  Agent") or at the office
of any agent or agents of the Corporation,  as may be designated by the Board of
Directors of the  Corporation,  of this  Warrant  Certificate  accompanied  by a
written  notice in the form attached  hereto  stating that such holder elects to
exercise  all  or a  specified  number  of  the  Warrants  evidenced  hereby  in
accordance  with the  provisions  of this Section 1 and  specifying  the name or
names in which such holder wishes the certificate or certificates  for shares of
Common Stock to be issued and (b) payment of the  Exercise  Price for the shares
of Common Stock issuable upon exercise of such Warrants. Payment of the Exercise
Price  shall be made in cash by  cashier's  check.  In case  such  notice  shall
specify a name or names other than that of such  holder,  such  notice  shall be
accompanied by payment of all transfer taxes payable upon the issuance of shares
of Common Stock in such name or names.  Other than such taxes,  the  Corporation
will pay any and all issue and other  taxes  (other  than taxes based on income)
that may be  payable in  respect  of any issue or  delivery  of shares of Common
Stock on exercise of the Warrants  evidenced hereby. As promptly as practicable,
and in any event within five  Business  Days after the surrender of this Warrant

<PAGE>

Certificate, receipt of such notice relating thereto and payment of the Exercise
Price for the number of shares issuable upon exercise of the Warrants  evidenced
hereby then being  exercised  and, if  applicable,  all  transfer  taxes (or the
demonstration  to the  satisfaction of the Corporation that such taxes have been
paid),  the Corporation  shall deliver or cause to be delivered (i) certificates
representing  the number of validly issued,  fully paid and  nonassessable  full
shares of Common Stock  issuable  upon the exercise of such Warrants and (ii) if
less than the full number of Warrants evidenced hereby are then being exercised,
a new Warrant  Certificate  or  Certificates,  of like tenor,  for the number of
Warrants evidenced by this Warrant  Certificate less the number of Warrants then
being exercised. Such exercise shall be deemed to have been made at the close of
business  on the  date of  giving  of such  notice,  surrender  of this  Warrant
Certificate and payment of the Exercise Price and transfer takes as aforesaid so
that the person  entitled to receive  shares of Common Stock upon such  exercise
shall be treated  for all  purposes as having  become the record  holder of such
shares of Common  Stock at such time.  No such  surrender  shall be effective to
constitute  the person  entitled  to receive  such  shares as the record  holder
thereof while the transfer books of the  Corporation for Common Stock are closed
for any  purpose  (but not for any  period in  excess of 15 days);  but any such
surrender of this Warrant  Certificate for exercise during any period while such
books are so closed shall become  effective  for exercise  immediately  upon the
reopening  of such  books  as if the  exercise  had been  made on the date  this
Warrant  Certificate  was  surrendered  and for the Number  Issuable  and at the
Exercise Price in effect at the date of such surrender.

     The  registered  holder  hereof shall have the (a) right at any time within
one year after the date hereof to elect to forego the second year of some or all
of the Warrants evidenced hereby and (b) upon such election the right thereafter
until  5:00  p.m.,  New York City time,  on  October  4, 1996 to  exercise  such
Warrants at an exercise price of $5.00 (increased or decreased,  as the case may
be, to reflect  the effect of each  adjustment  made,  at any time prior to such
exchange,  to the Exercise  Price pursuant to Section 2 as if the Exercise Price
of this Warrant had been $5.00 since the date hereof).  Upon such election,  the
Company shall  extinguish,  as an adjustment to the purchase price paid for such
Warrants,  for each such Warrant for which such election has been made, $0.37 of
the Principal Amount (as defined in the Note) due under the Note upon payment of
the interest due on such extinguished amount for the period from the date hereof
through the date of such election.

     In  connection  with the  exercise of any  Warrants  evidenced  hereby,  no
fractions  of shares of Common  Stock shall be issued,  but in lieu  thereof the
Corporation  shall pay a cash adjustment in respect of such fractional  interest
in an amount equal to such fractional  interest multiplied by the Current Market
Price (as defined in Section 12) per share of Common  Stock on the date on which
such Warrants are deemed to have been  exercised.  If more than one such Warrant
shall be  exercised by the holder  thereof at the same time,  the number of full
shares of Common Stock  issuable on such exercise shall be computed on the basis
of the total number of Warrants so exercised.

     2. (a) The Number Issuable shall be subject to adjustment from time to time
as follows:

          (i) In case the  Corporation  shall  at any time or from  time to time
     after the Issue Date (as  defined in Section 12) (A) pay a dividend or make
     a  distribution,  on the  outstanding  shares of Common  Stock in shares of
     Common Stock,  (B) subdivide the  outstanding  shares of Common Stock,  (C)
     combine the  outstanding  shares of Common  Stock into a smaller  number of
     shares or (D) issue by  reclassification  of the shares of Common Stock any
     shares of capital stock of the  Corporation,  then,  and in each such case,
     the Number Issuable in effect immediately prior to such event or the record
     date therefor,  whichever is earlier,  shall be adjusted so that the holder
     of any Warrant evidenced hereby  thereafter  exercised shall be entitled to
     receive  the number of shares of Common  Stock or other  securities  of the
     Corporation  which such holder would have owned or been entitled to receive
     after the occurrence of any of the events described above, had such Warrant
     been  exercised  immediately  prior to the  occurrence of such event or the
     record date therefor,  whichever is earlier. An adjustment made pursuant to
     this clause (i) shall become effective (A) in the case of any such dividend
     or distribution, immediately after the close of business on the record date
     for the  determination  of holders of shares of Common  Stock  entitled  to
     receive  such  dividend  or  distribution  or (B) in the  case of any  such
     subdivision,  combination or reclassification,  at the close of business on
     the day upon which such corporate action becomes effective.


<PAGE>

          (ii) In case the  Corporation  shall at any time or from  time to time
     after the Issue  Date  distribute  to all  holders  of its shares of Common
     Stock (including any distribution made in connection with a merger in which
     the   Corporation   is  the  surviving   corporation),   evidences  of  its
     indebtedness, securities of the Company (other than Common Stock) or assets
     (excluding  cash  dividends or  distributions  referred to in paragraph (i)
     above) or rights,  options or  warrants,  or  convertible  or  exchangeable
     securities  containing the right to subscribe for or purchase securities of
     the  Company  or  shares  of Common  Stock,  then in each  case the  Number
     Issuable  thereafter  upon the exercise of each Warrant shall be determined
     by multiplying  the Number Issuable  theretofore  upon the exercise of each
     Warrant by a fraction,  the numerator shall be the Current Market Price per
     share of Common Stock on the date of such distribution; or, if established,
     the record date for the  determination of holders of shares of Common Stock
     entitled to receive such  distribution,  and of which the denominator shall
     be such  Current  Market Price per share of Common Stock less the then Fair
     Market Value (as  determined in good faith by the Board of Directors of the
     Corporation whose determination shall be conclusive) of the portion of such
     evidences of  indebtedness  securities or assets so  distributed or of such
     subscription  rights,  options  or  warrants,  or of  such  convertible  or
     exchangeable  securities  applicable  to one  share of Common  Stock.  Such
     adjustment shall be made whenever any such  distribution is made, and shall
     become effective on the date of distribution retroactive to the record date
     for  the   determination   of   shareholders   entitled  to  receive   such
     distribution.

          (iii) For  purposes  of this  paragraph  (a),  the number of shares of
     Common Stock at any time outstanding shall not include any shares of Common
     Stock then owned or held by or for the account of the Corporation.

          (iv) The term  "dividend",  as used in this paragraph (a) shall mean a
     dividend  or  other  distribution  upon  stock  of the  Corporation  except
     pursuant   to  the  Rights   Agreement   (as   defined   in  Section   12).
     Notwithstanding  anything  in this  Section 2 to the  contrary,  the Number
     Issuable   shall  not  be  adjusted  as  a  result  of  (A)  any  dividend,
     distribution or issuance of securities of the  Corporation  pursuant to the
     Rights  Agreement  or (B)  any  dividend  to  stockholders  of  put  rights
     entitling  the  holder  thereof  to sell  shares  of  Common  Stock  to the
     Corporation  at a  specific  price  which may be in  excess of the  Current
     Market Price of Common Stock at the time such put rights are distributed.

          (v)  Notwithstanding  anything in this  paragraph (a) to the contrary,
     the  Corporation  shall not be required to give effect to any adjustment in
     the  Number  Issuable  unless  and  until  the  net  effect  of one or more
     adjustments (each of which shall be carried  forward),  determined as above
     provided,  shall have  resulted  in a change in the Number  Issuable  by at
     least  one-hundredth  of one share of Common Stock, and when the cumulative
     net effect of more than one adjustment so determined shall be to change the
     Number  Issuable by at least  one-hundredth  of one share of Common  Stock,
     such change in the Number Issuable shall thereupon be given effect.

          (vi)  Upon  the  expiration  of  any  rights,  options,   warrants  or
     convertible or exchangeable securities,  if any thereof shall have been the
     basis for an  adjustment  in the Number  Issuable  and the  Exercise  Price
     pursuant to Sections  2(a)(ii)  and (b),  respectively,  and shall not have
     been exercised, the Number Issuable and the Exercise Price shall, upon such
     expiration,  be  readjusted  and shall  thereafter be such as it would have
     been had it been  originally  adjusted or had the original  adjustment  not
     been  required,  as the case may be,  as if (A) the only  shares  of Common
     Stock so issued were the shares of Common Stock, if any, actually issued or
     sold upon the exercise of such rights, options,  warrants or convertible or
     exchangeable  securities and (B) such shares of Common Stock,  if any, were
     issued or sold for the  consideration  actually received by the Corporation
     upon such  exercise  plus the  aggregate  consideration,  if any,  actually
     received by the  Corporation  for the  issuance,  sale or grant of all such
     rights,  options,  warrants  or  convertible  or  exchangeable  securities,
     whether or not exercised.

          (vii) The certificate of any firm of independent public accountants of
     recognized  standing  selected by the Board of Directors of the Corporation
     (which may be the firm of independent public accountants regularly employed
     by the Corporation) shall be presumptively correct for any computation made
     under this paragraph (a).


<PAGE>

          (viii) If the  Corporation  shall take a record of the  holders of its
     Common  Stock for the  purpose of  entitling  them to receive a dividend or
     other  distribution,  and shall  thereafter and before the  distribution to
     stockholders  thereof  legally  abandon  its  plan to pay or  deliver  such
     dividend or  distribution,  then  thereafter,  no  adjustment in the Number
     Issuable  then in effect  shall be required by reason of the taking of such
     record.

          (ix) There  shall be no  adjustment  of the number of shares of Common
     Stock  issuable upon exercise of the Warrants  evidenced  hereby in case of
     the issuance of any stock of the  Corporation in a merger,  reorganization,
     acquisition or other similar  transaction except as set forth in paragraphs
     (a)(i), (a)(ii) and (c) of this Section 2.

     (b) The Exercise Price shall be subject to adjustment  from time to time as
follows:  upon each adjustment of the Number Issuable made pursuant to paragraph
(a) of this Section 2, the Exercise  Price  effective  immediately  prior to the
making of such adjustment shall thereafter be adjusted to be the amount obtained
by dividing (i) the product of (A) the applicable  Number  Issuable  immediately
prior to such adjustment and (B) the Exercise Price in effect  immediately prior
to  such  adjustment  by  (ii)  the  Number  Issuable   immediately  after  such
adjustment.

     (c)  In  case  of  any  capital   reorganization  or   reclassification  of
outstanding  shares of Common  Stock (other than a  reclassification  covered by
paragraph  (a)(i) of this Section 2), or in case of any  consolidation or merger
of the Corporation with or into another  corporation,  or in case of any sale or
conveyance  to another  corporation  of the  property of the  Corporation  as an
entirety or  substantially  as an entirety (each of the foregoing being referred
to as a  "Transaction"),  at the option of the holder of any  Warrant  evidenced
hereby (i) each such Warrant then  outstanding  shall  thereafter be exercisable
for,  in  lieu of the  shares  of  Common  Stock  issuable  upon  such  exercise
immediately  prior to consummation of such  Transaction,  the kind and amount of
shares of capital stock and other securities and property receivable  (including
cash) upon the  consummation  of such  Transaction by a holder of that number of
shares of Common Stock issuable upon exercise of such Warrant  immediately prior
to such Transaction  (including,  on a pro rata basis,  the cash,  securities or
property  received by holders of Common  Stock in any tender or  exchange  offer
that is a step in such Transaction), or (ii) each such Warrant shall entitle the
holder thereof to receive,  upon exercise thereof by presentation of the Warrant
Certificate  therefor and payment of the Exercise Price to the Surviving  Person
(as defined in Section 12) subsequent to the  consummation  of such  Transaction
(A) if the  Surviving  Person is a Qualified  Person (as defined in Section 12),
that number of shares of Survivor Common Stock (as defined in Section 12) of the
Surviving  Person  determined by  multiplying  the  applicable  Number  Issuable
immediately  prior to the  consummation of such  Transaction by a fraction,  the
numerator of which is the Current  Market Price of the Common Stock  immediately
prior to the  consummation  of such  Transaction and the denominator of which is
the Current  Market Price of the Survivor  Common Stock of the Surviving  Person
for  the  20  Trading  Days  immediately   preceding  the  consummation  of  the
Transaction  giving rise to the  adjustment in this  paragraph (c) or (B) if the
Surviving Person is not a Qualified Person, cash equal to the Fair Market Value,
as of the consummation of such Transaction  (computed without interest),  of the
securities or other property to which such holder would have been entitled under
clause (i) above, as determined by an independent  investment banking firm (with
an established  national  reputation as a valuer of equity  securities).  In any
such case, if necessary,  appropriate  adjustment (as determined by the Board of
Directors)  shall be made in the application of the provisions set forth in this
Section 2 with respect to rights and  interests  thereafter of the holder of the
Warrants  evidenced  hereby to the end that the  provisions set forth herein for
the  protection  of the purchase  rights of such  Warrants  shall  thereafter be
applicable,  as nearly as reasonably may be, to any such other shares of capital
stock and other securities and property  issuable upon exercise of such Warrants
remaining  outstanding  (with such  adjustments  in the  Exercise  Price and the
Number Issuable and such other adjustments in the provisions hereof as the Board
of Directors shall determine to be appropriate).  In case securities of property
other than Common Stock shall be issuable or  deliverable  upon  exercise of the
Warrants  evidenced  hereby as aforesaid,  then all references in this Section 2
shall be deemed to apply, so far as appropriate and as nearly as may be, to such
other securities or property.


<PAGE>

     Notwithstanding  anything contained herein to the contrary, the Corporation
will not effect any Transaction unless,  prior to the consummation  thereof, the
Surviving  Person  thereof shall  assume,  by written  instrument  mailed to the
holder of the  Warrants  evidenced  hereby,  the  obligation  to deliver to such
holder such cash,  shares of Survivor Common Stock or other  securities to which
such holder is entitled in  accordance  with the foregoing  provisions  and such
Surviving  Person  shall have  mailed to such  holder an opinion of  independent
counsel for such  Person  stating  that such  assumption  agreement  is a valid,
binding and enforceable agreement of the Surviving Person.

     3. In case at any time or from time to time  prior to the  Expiration  Date
the  Corporation  shall pay any dividend or make any other  distribution  to the
holders of its Common  Stock,  or shall offer for  subscription  pro rata to the
holders of its Common Stock any  additional  shares of stock of any class or any
other right, or there shall be any capital reorganization or reclassification of
the  Common  Stock  of  the  Corporation  or  consolidation  or  merger  of  the
Corporation  with or into  another  corporation,  or any sale or  conveyance  to
another  corporation  of the  property  of the  Corporation  as an  entirety  or
substantially  as an  entirety,  or there  shall be a voluntary  or  involuntary
dissolution,  liquidation or winding up of the Corporation,  then, in any one or
more of such cases,  the Corporation  shall give at least 10 days' prior written
notice  (the time of  mailing of such  notice  shall be deemed to be the time of
giving thereof) to the registered holder of the Warrants evidenced hereby at its
address  as shown on the books of the  Corporation  maintained  by the  Transfer
Agent thereof of the date on which (a) the books of the Corporation  shall close
or a record shall be taken for such stock dividend, distribution or subscription
rights or (b) such reorganization, reclassification, consolidation, merger, sale
or conveyance,  dissolution,  liquidation or winding up shall take place, as the
case may be;  provided,  that in the case of any  Transaction to which paragraph
(c) of Section 2 applies,  the  Corporation  shall give at least 30 days'  prior
written notice as aforesaid. Such notice shall also specify the date as of which
the  holders  of record of Common  Stock  shall  participate  in such  dividend,
distribution  or  subscription  rights or shall be entitled  to  exchange  their
Common  Stock  for   securities  or  other   property   deliverable   upon  such
reorganization,  reclassification,  consolidation, merger, sale or conveyance or
participate in such dissolution,  liquidation or winding up, as the case may be.
Failure to give such notice shall not invalidate any action so taken.

     4. Upon any increase or decrease in the Number  Issuable or any  adjustment
of the  Exercise  Price,  then,  and in each such case,  the  Corporation  shall
promptly  deliver to the  Transfer  Agent of the Warrants  and Common  Stock,  a
certificate  signed by the President or a Vice President and by the Treasurer or
an  Assistant  Treasurer  or the  Secretary  or an  Assistant  Secretary  of the
Corporation   setting  forth  in  reasonable  detail  the  event  requiring  the
adjustment and the method by which such adjustment was calculated and specifying
the increased or decreased Number Issuable and the Exercise Price then in effect
following such adjustment.  The Corporation shall also promptly after the making
of such adjustment give written notice to the registered  holder of the Warrants
evidenced  hereby  at its  address  as  shown on the  books  of the  Corporation
maintained by the Transfer Agent thereof, which notice shall state the increased
or decreased  Number  Issuable and the Exercise  Price then in effect  following
such  adjustment  and  shall  set  forth in  reasonable  detail  the  method  of
calculation  of  each  and  a  brief  statement  of  the  facts  requiring  such
adjustment.  Where  appropriate,  such  notice  to the  holder  of the  Warrants
evidenced  hereby may be given in  advance  and  included  as part of the notice
required under the provisions of Section 3.

     5. The Corporation covenants and agrees that all shares of capital stock of
the Corporation which may be issued upon the exercise of the Warrants  evidenced
hereby will be duly authorized, validly issued and fully paid and nonassessable.
The Corporation  further  covenants and agrees that,  until the Expiration Date,
the  Corporation  will at all times reserve such number of shares of its capital
stock as may be sufficient to permit the exercise in full of such Warrants.

     6. The person in whose name this Warrant Certificate is registered shall be
deemed the owner hereof and of the Warrants  evidenced  hereby for all purposes.
The registered  holder of this Warrant  Certificate shall not be entitled to any
rights whatsoever as a stockholder of the Corporation except as herein provided.


<PAGE>

     7. The rights represented by this Warrant Certificate  (including,  but not
limited to, the  Warrants  evidenced  hereby)  shall not be  transferred,  sold,
assigned or  hypothecated,  except as permitted by the Purchase  Agreement.  Any
transfer shall be effected by the surrender of this Warrant  Certificate,  along
with the form of assignment attached hereto,  properly completed and executed by
the  registered  holder  hereof,  at  the  principal  executive  office  of  the
Corporation.  Thereupon,  the  Corporation  shall  issue  in the  name or  names
specified  by the  registered  holder  hereof  and,  in the  event of a  partial
transfer, in the name of the registered holder hereof, a new Warrant Certificate
or Certificates evidencing the right to purchase such number of shares of Common
Stock as shall be equal to the number of shares of Common Stock then purchasable
hereunder.

     8. The Corporation  covenants that it shall, at its expense,  promptly upon
surrender of this Warrant  Certificate at the principal  executive office of the
Corporation,  execute and deliver to the registered  holder hereof a new Warrant
Certificate or  Certificates  in  denominations  specified by such holder for an
aggregate  number of Warrants equal to the number of Warrants  evidenced by this
Warrant Certificate.

     9. Upon receipt of evidence  satisfactory  to the  Corporation of the loss,
theft, destruction or mutilation of this Warrant Certificate and, in the case of
loss,  theft or destruction,  upon delivery of an indemnity  satisfactory to the
Corporation,  or, in the case of  mutilation,  upon  surrender and  cancellation
thereof,  the Corporation will issue a new Warrant Certificate of like tenor for
a number of Warrants  equal to the number of Warrants  evidenced by this Warrant
Certificate.

     10. This Warrant  Certificate shall be construed and enforced in accordance
with the laws of the State of Delaware.

     11. Nothing in this Warrant  Certificate  shall be construed to give to any
Person other than the Corporation and the registered  holder hereof any legal or
equitable  right,  remedy or claim  under  this  Warrant  Certificate,  and this
Warrant  Certificate  shall  be  for  the  sole  and  exclusive  benefit  of the
Corporation and such registered holder.

     12. For the purposes of this Warrant Certificate, the following terms shall
be defined as follows:

     "Business Day" shall mean any day other than a Saturday, Sunday or a day on
which banking  institutions in the State of New York are authorized or obligated
by law to close.

     "Current Market Price",  when used with reference to shares of Common Stock
or other  securities  on any date,  shall  mean the  closing  price per share of
Common Stock or such other securities on such date and, when used with reference
to shares of Common  Stock or other  securities  for any period,  shall mean the
average  of the daily  closing  prices  per share of Common  Stock or such other
securities  for such  period.  The closing  price for each day shall be the last
sale price,  regular  way, or, in case no such sale takes place on such day, the
average  of the  closing  bid and asked  prices,  regular  way,  in each case as
reported in the principal consolidated transaction reporting system with respect
to securities  listed or admitted to trading on the New York Stock  Exchange or,
if Common Stock or such other  securities  are not listed or admitted to trading
on the New York Stock  Exchange,  in each case,  as  reported  in the  principal
consolidated  transaction  reporting system with respect to securities listed on
the principal national  securities  exchange on which Common Stock or such other
securities  are listed or admitted to trading or, if Common  Stock or such other
securities  are not listed or  admitted  to trading on any  national  securities
exchange,  in each case, the last quoted price or, if not so quoted, the average
of the high bid and low asked prices in the over-the-counter market, as reported
by the National  Association of Securities  Dealers,  Inc.  Automated  Quotation
System or such other system then in use, or, if on any such date Common Stock or
such other securities are not quoted by any such organization, in each case, the
average of the  closing  bid and asked  prices as  furnished  by a  professional
market maker making a market in Common Stock or other such  securities  selected
by the Board of  Directors  of the  Corporation.  If Common  Stock or such other

<PAGE>

securities  are not  publicly  held or so listed or  publicly  traded,  "Current
Market  Price"  shall mean the Fair Market Value per share of Common Stock or of
such other  securities  as determined in good faith by the Board of Directors of
the Corporation  based on an opinion of an independent  investment  banking firm
with an established  reputation as a valuer of securities,  which opinion may be
based on such assumptions as such firm shall deem necessary and appropriate.

     "Exchange Act" shall mean the Securities Exchange Act of 1934, as amended.

     "Fair Market Value" shall mean the amount which a willing buyer would pay a
willing seller in an arm's-length transaction.

     "Issue Date" shall mean the first date on which Warrants are issued.

     "Person" shall mean any individual, partnership, joint venture, joint stock
company,   association,   corporation,   trust,   unincorporated   organization,
government or department or agency of government, or other entity.

     "Qualified  Person"  shall mean any Person that,  immediately  after giving
effect to the  applicable  Transaction,  (i) is a solvent  corporation  or other
entity  organized  under the laws of any State of the  United  States of America
having its common stock or, in the case of an entity  other than a  corporation,
equivalent  equity  securities,  listed  on the New  York  Stock  Exchange,  the
American  Stock Exchange or the NASDAQ  National  Market System or any successor
thereto or other comparable  system,  and such common stock or equivalent equity
security  continues  to meet  the  requirements  for  such  listing  and (ii) is
required to file,  and in each of its three fiscal years  immediately  preceding
the  consummation  of the  applicable  Transaction  (or since its inception) has
filed,  reports with the Securities and Exchange  Commission pursuant to Section
13 or 15(d) of the Exchange Act.

     "Rights"  shall mean any rights to purchase  securities of the  Corporation
issued pursuant to any Rights Agreement.

     "Rights  Agreement"  shall mean the Rights  Agreement dated as of April 24,
1994 between the Corporation  and American Stock Transfer and Trust Company,  as
amended  and as it may be further  amended  from time to time,  and any  similar
rights agreement that may hereafter be adopted by the Corporation,  as it may be
amended from time to time.

     "Subsidiary" of any Person means any corporation or other entity of which a
majority of the voting power of the voting equity  securities or equity interest
is owned, directly or indirectly, by such Person.

     "Surviving  Person"  shall mean the  continuing  or  surviving  Person of a
merger,  consolidation  or other corporate  combination,  the Person receiving a
transfer  of all or a  substantial  part of the  properties  and  assets  of the
Corporation, or the Person consolidating with or merging into the Corporation in
a merger,  consolidation or other corporate combination in which the Corporation
is the continuing or surviving  Person,  but in connection with which the Common
Stock  of the  Corporation  is  exchanged,  converted  or  reinstated  into  the
securities of any other Person or cash or any other property; provided, however,
that, if such Surviving Person is a direct or indirect Subsidiary of a Qualified
Person,  the parent  entity that is a Qualified  Person  shall be the  Surviving
Person.

     "Survivor Common Stock" with respect to any Person shall mean any shares of
any class or series of capital  stock of such Person which has no  preference or
priority in the payment of dividends or in the  distribution  of assets upon any
voluntary or involuntary  liquidation,  dissolution or winding up of such Person
and which is not subject to redemption by such Person; provided,  however, that,
if at any time there shall be more than one such class or series,  the shares of
each such class and series  issuable  upon  exercise of the Warrants  then being
exercised shall be substantially in the proportion to the total number of shares
of each such class and series.

     "Trading  Day"  means a day on  which  the  principal  national  securities
exchange on which the Common  Stock is listed or admitted to trading is open for
the transaction of business or, if the Common Stock is not listed or admitted to
trading on any national securities exchange, a Business Day.


<PAGE>

     IN WITNESS WHEREOF,  the Corporation has caused this Warrant Certificate to
be duly executed, all as of the day and year first above written.


                                    DIANON SYSTEMS, INC.


                                    By:      /s/Richard A. Sandberg
                                       ------------------------------------
                                        Name: Richard A. Sandberg
                                        Title:President, Chairman and Chief
                                              Executive Officer


<PAGE>


                              DIANON SYSTEMS, INC.

                              ELECTION TO PURCHASE


DIANON SYSTEMS, INC.
200 Watson Boulevard
Stratford, Connecticut  06497


     The undersigned hereby irrevocably elects to exercise the right of purchase
represented by the Warrant surrendered herewith for, and to purchase thereunder,
- --------------------------------- shares of Common Stock (the "Shares") provided
for therein, and requests that certificates for the Shares be issued in the name
of:*

- -----------------------------------------------------------------------------

- -----------------------------------------------------------------------------
             (Please Print Name, Address and Social Security Number)

and,  if said  number of Shares  shall not be all of the shares of Common  Stock
purchasable under the Warrant, that a new Warrant certificate for the balance of
the shares of Common Stock purchasable under the Warrant surrendered herewith be
registered in the name of the undersigned Warrantholder or the Assignee* thereof
as indicated below and delivered to the address stated below:

            Dated: ------------------------------, 19---

            Name of Warrantholder or
               Assignee (Please Print):-------------------------------

            Address:--------------------------------------------------

            Signature:------------------------------------------------**

         Signature Guaranteed:----------------------------------------
                              Signature of Guarantor
                              [FORM OF ASSIGNMENT]

     (To be executed by the registered holder if such holder desires to transfer
the Warrant Certificate.)

     FOR VALUE RECEIVED  --------------------------------  hereby sells, assigns
and   transfers   unto   ---------------------------------------   the   Warrant
Certificate  surrendered  herewith,  together with all right, title and interest
therein,    and    does    hereby    irrevocably    constitute    and    appoint
- -----------------------------  Attorney,  to transfer the Warrant Certificate on
the books of the Corporation named therein, with full power of substitution.


- ----------
*     The  Warrant  and  the  Stock  and  Warrant  Purchase   Agreement  contain
      restrictions on sale, assignment or transfer of this Warrant.

**    Note: The above  signature must  correspond  with the name as written upon
      the  face  of  this  Warrant  certificate  in  every  particular,  without
      alteration or  enlargement or any change  whatsoever,  unless this Warrant
      has been assigned.


<PAGE>

Dated: ------------------------------     --------------------------------------
                                          (Signature   must   conform   in   all
                                          respects   to   name  of   holder   as
                                          specified  on the face of the  Warrant
                                          Certificate.)

     If said number of shares of Common  Stock is less than all of the shares of
Common Stock purchasable under the Warrant Certificate surrendered herewith, the
undersigned  requests that a new Warrant Certificate  representing the remaining
balance of the shares of Common Stock be registered in the name of whose address
is and that such Warrant Certificate be delivered to whose address is .


Signature Guaranteed:




- ------------------------------





                                                                   Exhibit 10.32


                                 PROMISSORY NOTE


$296,000                                                  Stratford, Connecticut
                                                                 October 4, 1995


     FOR VALUE RECEIVED, the undersigned, G.S. BECKWITH GILBERT ("Mr. Gilbert"),
hereby  promises  to pay to the  order  of  DIANON  SYSTEMS,  INC.,  a  Delaware
corporation or its successors (the  "Holder"),  the principal sum of Two Hundred
Ninety-Six  Thousand DOLLARS ($296,000) or such lesser amount as may then be the
unpaid principal balance hereof (the "Principal Amount"), together with interest
thereon,  payable on October 4, 1997 by certified or official bank check or wire
transfer of immediately available funds to an account designated by the Holder.

     Mr.  Gilbert  promises  to pay  interest  on the  Principal  Amount of this
promissory  note (this "Note") from the date hereof until such Principal  Amount
is paid in full at the fixed  rate of 7% per  annum,  such  interest  payable in
arrears on October 4, 1997; provided,  however, that any Principal Amount hereof
not paid when due and, to the fullest  extent  permitted by applicable  law, any
overdue interest shall bear interest at a rate per annum equal to 10% (after, as
well as before, any judgment),  payable on demand.  Interest shall be calculated
on the basis of a 360-day year for the actual number of days elapsed.

     This Note is issued in connection with the transactions contemplated by the
Stock  and  Warrant  Purchase  Agreement,  dated  as of  October  4,  1995  (the
"Agreement")  among the Gilbert  Family Trust (the "Trust"),  the G.S.  Beckwith
Gilbert I.R.A. Contributory Account (the "IRA"), Mr. Gilbert and the Holder, and
the Warrants  issued by the Holder in connection  therewith and  represented  by
Warrant Certificate No. W-1 (the "W-1 Warrants").  Except as otherwise indicated
herein capitalized terms used in this Note are defined in the Agreement.

     This  Principal  Amount due under this Note and the date on which  interest
payments are due are subject to adjustment  in accordance  with the terms of the
second paragraph of Section 1 of the W-1 Warrants.

     This Note shall be binding upon Mr.  Gilbert and his  successors  and shall
inure to the benefit of Mr. Gilbert and his successors.

     Mr.  Gilbert hereby waives  presentment,  demand,  notice,  protest and all
other  demands  and  notices  in  connection  with  the  delivery,   acceptance,
performance or enforcement of this Note.

     The provisions of this Note may be amended, modified, changed or terminated
only be an agreement in writing signed by Mr. Gilbert and the Holder.

     If at any time the indebtedness evidenced by this Note is collected through
legal  proceedings  or  this  Note is  placed  in the  hands  of  attorneys  for
collection,  Mr.  Gilbert  and each  endorser  of this Note  hereby  jointly and
severally  agree to pay all  costs  and  expenses  (including  attorneys'  fees)
incurred by the Holder in collecting or attempting to collect such indebtedness.

     If any  payment on this Note  becomes due and payable on a day other than a
Business Day (as hereinafter defined), the maturity thereof shall be extended to
the  immediately  following  Business Day and interest  shall continue to accrue
during  such  extension.  "Business  Day" means any day other than a Saturday or
Sunday  or any  other day on which  commercial  banks in New York,  New York are
authorized or obligated by law to close.

     This Note is non-transferrable.


<PAGE>

     THE BORROWER HEREBY  KNOWINGLY,  VOLUNTARILY AND  INTENTIONALLY  WAIVES ANY
RIGHT HE MAY HAVE TO A TRIAL BY JURY OF ANY DISPUTE ARISING UNDER OR RELATING TO
THIS  NOTE  AND  AGREES  THAT ANY SUCH  DISPUTES  SHALL BE TRIED  BEFORE A JUDGE
SITTING WITHOUT A JURY.

     THIS NOTE IS GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH,
THE LAWS OF  CONNECTICUT  WITHOUT  REGARD  TO THE  CONFLICT  OF LAWS  PROVISIONS
THEREOF.


                                          /s/ G. S. Beckwith Gilbert
                                          --------------------------
                                          G. S. Beckwith Gilbert




                                                                   Exhibit 10.33
                              DIANON SYSTEMS, INC.

                                                            Grant No.

                               STOCK OPTION GRANT


Optionee:               Andre deBruin        Total No. of Shares          10,000

Date of Grant:              10/24/1996       Exercise Price Per Share     $7.125

Termination Date:           10/23/2006                                $71,250.00


     DIANON  SYSTEMS,  INC.  (the  "Company")  has this day granted to you,  the
optionee  named  above,  an option  to  purchase  shares of common  stock of the
Company  ("Common  Stock").  This option is granted in replacement of the option
which was previously granted to you on June 4, 1993.

     The details of your option are as follows:

     1. The total number of shares subject to this option is as set forth above.
Subject to the limitations contained herein, this option shall be exercisable on
or after the date of the vesting of such option as follows:

<TABLE>
<CAPTION>
     Percentage of Shares              Date of Earliest Exercise (Vesting)
     --------------------              -----------------------------------

            <S>                                    <C>
            100%                                   10/24/96
</TABLE>

     2. (a) The per share  exercise  price of this option is as set forth on the
face of this option grant,  and is the same as the exercise  price of the option
granted to you on June 4, 1993 which this option replaces.

        (b) Payment of the exercise price is due in  full in cash upon  exercise
when the  aggregate  option  exercise  price for the shares  being  purchased is
$2,500 or less;  but when the  aggregate  exercise  price for the  shares  being
purchased  exceeds  $2,500,  you may elect to make payment of the exercise price
under one of the following alternatives:

               (i)  Payment  of the  exercise  price  in cash at the time of the
          exercise;

               (ii) (a) Payment of not less than 10% of the  aggregate  exercise
          price due at the time of  exercise  in cash,  (b) not less than 10% of
          said exercise price, plus simple interest at the lowest rate which, at
          the time of exercise,  will prevent any imputation of higher  interest
          under  Section 483 of the Internal  Revenue  Code,  per year after the
          time of  exercise,  with (c) final  payment  of the  remainder  of the
          exercise  price,  plus  interest,  due five  (5)  years  from  date of
          exercise,  provided that as a part of your written  notice of exercise
          you give notice of the election of this deferred payment  arrangement,
          and to  secure  the  payment  of the  deferred  purchase  price to the
          Company  hereunder,  which such  election  you tender to the Company a
          security agreement  satisfactory to the Company covering the purchased
          shares;

               (iii) Provided that at the time of exercise the Company's  common
          stock is  publicly  traded and  quoted  regularly  in the Wall  Street
          Journal,  payment by delivery of shares of common stock of the Company
          which  you have  owned for at least six moths and which at the time of
          exercise  are  owned  by you  free and  clear  of any  liens,  claims,
          encumbrances or security interests, which common stock shall be valued
          (i) if listed on a national securities exchange or the Nasdaq national
          market,  at the average  closing  price for the ten (10)  trading days

<PAGE>

          immediately  preceding  the date of exercise or (ii)  otherwise at the
          average of the closing bid and ask  quotations  published  in the Wall
          Street Journal for the ten (10) trading days immediately preceding the
          date of exercise; or

               (iv)  Payment in the form of any other legal  consideration  that
          may be acceptable to the Board of Directors of the Company in its sole
          discretion at the time of exercise.

     3. The minimum  number of shares  with  respect to which this option may be
exercised at any one time is one hundred (100), however, if the number of shares
subject to exercise is less than one hundred, the option must be exercised as to
all of such shares.

     4.  Notwithstanding  anything to the contrary contained herein, this option
may not be exercised unless the shares issuable upon exercise of this option are
then registered under the Securities Act of 1933, as amended (the "Act"),  or if
such shares are not then  registered,  the Company  has  determined  in its sole
discretion  that such  exercise and issuance  would be exempt from  registration
under the Act.  Your right to exercise  this option is also  conditioned  on the
Company's  listing of the shares  subject to this option on the Nasdaq  national
market or any  securities  exchange on which the Common Stock is then traded and
compliance with any applicable  securities  registration or other securities law
requirements.

     5. The term of this option  commences on the date hereof and  terminates on
the date set forth on the face of this option grant.

     6.  This  option  may  be  exercised,  to the  extent  specified  above  by
delivering  a  notice  of  exercise  together  with  the  exercise  price to the
Secretary of the Company,  or to such other person as the Company may designate,
during regular  business hours,  together with such additional  documents as the
Company may then require.

     7.  This  option  is not  transferable,  except  by will or by the  laws of
descent and distribution, and is exercisable during your life only by you.

     8. Any notices  provided  for in this option  shall be given in writing and
shall be deemed  effectively  given  upon  receipt  or,  in the case of  notices
delivered  by the  Company  to you,  five (5) days  after  deposit in the United
States mail, postage prepaid, addressed to the optionee at the address specified
below or at such other address as the optionee  hereafter  designates by written
notice delivered to the Company.

     9.  Whenever  shares are to be issued in  satisfaction  of this  option you
shall remit to the Company an amount sufficient to satisfy federal, state, local
or other  withholding  tax  requirements  if and to the extent  required  by law
(whether  so  required  to secure for the  Company an  otherwise  available  tax
deduction  or  otherwise)   prior  to  the  delivery  of  any   certificate   or
certifi-cates for such shares.

     10.  In the event of any  merger,  reorganization,  consolidation,  sale of
substantially  all  assets,  recapitalization,   stock  dividend,  stock  split,
spin-off,  split-off,  distribution  of  assets  or other  change  in  corporate
structure  affecting the Common Stock, a substitution  of adjustment,  as may be
determined  to be  appropriate  by the Board of  Directors  or the  Compensation
Committee  of the  Board  ("the  Compensation  Committee")  shall be made in the
number, option price and kind of shares covered by this Option; provided however
that no such  adjustment  shall increase or decrease the aggregate  value of any
outstanding portion of this Option.

     11. The Board of Directors and the Compensation Committee reserve the right
to  interpret  the  provisions  of  this  Option,  make  any  necessary  factual
determinations,   and  adopt,  amend,  and  rescind   administrative  rules  and
procedures in connection with the exercise of this Option. Any interpretation or
determination  by the  Board or the  Compensation  Committee  shall be final and
binding.


<PAGE>


The undersigned:

Dated This  24th    day of         (a) Acknowledges receipt of the fore-

 October           , 1996   .      going option and understands that all
- -------------------      ---
                                   rights and liabilities connected with

                                   this option are set forth in the Option,

                                   (b) Acknowledges that as of the date

Very truly yours,                  of grant of this option, it sets
DIANON SYSTEMS, INC.
                                   forth the entire understanding
Duly authorized on
behalf of the                      between the undersigned optionee and
Board of Directors
                                   the Company regarding the acquisition of

                                       stock from the
Company and supersedes all         prior oral and written agreements on that

                                   subject with the

exception of the following         agreements only: (if none, so state)



                                    /s/ Andre deBruin
                                 ----------------------------------------

                      Address:      2545 Central Ave.
                                 ----------------------------------------

                                    Boulder, CO  80301
                                 ----------------------------------------




                                                                   Exhibit 10.34
                              DIANON SYSTEMS, INC.

                                                            Grant No.

                               STOCK OPTION GRANT


Optionee:            Jeffrey L. Sklar        Total No. of Shares          10,000

Date of Grant:              11/04/1996       Exercise Price Per Share     $6.375

Termination Date:           08/04/1999                                $63,750.00


     DIANON  SYSTEMS,  INC.  (the  "Company")  has this day granted to you,  the
optionee  named  above,  an option  to  purchase  shares of common  stock of the
Company  ("Common  Stock") This option is granted in  replacement  of the option
which was previously  granted to you on August 3, 1994 and is issued pursuant to
the 1996 Stock Incentive Plan ("the Plan").

     The details of your option are as follows:

     1. The total number of shares subject to this option is as set forth above.
Subject to the limitations contained herein, this option shall be exercisable on
or after the date of the vesting of such option as follows:

<TABLE>
<CAPTION>
     Percentage of Shares              Date of Earliest Exercise (Vesting)
     --------------------              -----------------------------------
            <S>                                    <C>
            40%                                    11/04/96
            20%                                    08/04/97
            20%                                    08/04/98
            20%                                    08/04/99
</TABLE>

     2. (a) The per share  exercise  price of this option is as set forth on the
face of this option grant.

     (b) Payment of the exercise price is due in full in cash upon exercise when
the aggregate  option exercise price for the shares being purchased is $2,500 or
less;  but when the  aggregate  exercise  price for the shares  being  purchased
exceeds $2,500, you may elect to make payment of the exercise price under one of
the following alternatives:

               (i)  Payment  of the  exercise  price  in cash at the time of the
          exercise;

               (ii) (a) Payment of not less than 10% of the  aggregate  exercise
          price due at the time of  exercise  in cash,  (b) not less than 10% of
          said exercise price, plus simple interest at the lowest rate which, at
          the time of exercise,  will prevent any imputation of higher  interest
          under  Section 483 of the Internal  Revenue  Code,  per year after the
          time of  exercise,  with (c) final  payment  of the  remainder  of the
          exercise  price,  plus  interest,  due five  (5)  years  from  date of
          exercise,  provided that as a part of your written  notice of exercise
          you give notice of the election of this deferred payment  arrangement,
          and to  secure  the  payment  of the  deferred  purchase  price to the
          Company  hereunder,  which such  election  you tender to the Company a
          security agreement  satisfactory to the Company covering the purchased
          shares;

               (iii) Provided that at the time of exercise the Company's  common
          stock is  publicly  traded and  quoted  regularly  in the Wall  Street
          Journal,  payment by delivery of shares of common stock of the Company
          which  you have  owned for at least six moths and which at the time of

<PAGE>

          exercise  are  owned  by you  free and  clear  of any  liens,  claims,
          encumbrances or security interests, which common stock shall be valued
          (i) if listed on a national securities exchange or the Nasdaq national
          market,  at the average  closing  price for the ten (10)  trading days
          immediately  preceding  the date of exercise or (ii)  otherwise at the
          average of the closing bid and ask  quotations  published  in the Wall
          Street Journal for the ten (10) trading days immediately preceding the
          date of exercise; or

               (iv)  Payment in the form of any other legal  consideration  that
          may be acceptable to the Board of Directors of the Company in its sole
          discretion at the time of exercise.

     3. The minimum  number of shares  with  respect to which this option may be
exercised at any one time is one hundred (100), however, if the number of shares
subject to exercise is less than one hundred, the option must be exercised as to
all of such shares.

     4.  Notwithstanding  anything to the contrary contained herein, this option
may not be exercised unless the shares issuable upon exercise of this option are
then registered under the Securities Act of 1933, as amended (the "Act"),  or if
such shares are not then  registered,  the Company  has  determined  in its sole
discretion  that such  exercise and issuance  would be exempt from  registration
under the Act.  Your right to exercise  this option is also  conditioned  on the
Company's  listing of the shares  subject to this option on the Nasdaq  national
market or any  securities  exchange on which the Common Stock is then traded and
compliance with any applicable  securities  registration or other securities law
requirements.

     5. The term of this option  commences on the date hereof and  terminates on
the date set forth on the face of this option grant.

     6.  This  option  may  be  exercised,  to the  extent  specified  above  by
delivering  a  notice  of  exercise  together  with  the  exercise  price to the
Secretary of the Company,  or to such other person as the Company may designate,
during regular  business hours,  together with such additional  documents as the
Company may then require.

     7.  This  option  is not  transferable,  except  by will or by the  laws of
descent and distribution, and is exercisable during your life only by you.

     8. Any notices  provided  for in this option  shall be given in writing and
shall be deemed  effectively  given  upon  receipt  or,  in the case of  notices
delivered  by the  Company  to you,  five (5) days  after  deposit in the United
States mail, postage prepaid, addressed to the optionee at the address specified
below or at such other address as the optionee  hereafter  designates by written
notice delivered to the Company.

     9.  Whenever  shares are to be issued in  satisfaction  of this  option you
shall remit to the Company an amount sufficient to satisfy federal, state, local
or other  withholding  tax  requirements  if and to the extent  required  by law
(whether  so  required  to secure for the  Company an  otherwise  available  tax
deduction  or  otherwise)   prior  to  the  delivery  of  any   certificate   or
certifi-cates for such shares.

     10.  In the event of any  merger,  reorganization,  consolidation,  sale of
substantially  all  assets,  recapitalization,   stock  dividend,  stock  split,
spin-off,  split-off,  distribution  of  assets  or other  change  in  corporate
structure  affecting the Common Stock, a substitution  of adjustment,  as may be
determined  to be  appropriate  by the Board of  Directors  or the  Compensation
Committee  of the  Board  ("the  Compensation  Committee")  shall be made in the
number, option price and kind of shares covered by this Option; provided however
that no such  adjustment  shall increase or decrease the aggregate  value of any
outstanding portion of this Option.

     11. The Board of Directors and the Compensation Committee reserve the right
to  interpret  the  provisions  of  this  Option,  make  any  necessary  factual
determinations,   and  adopt,  amend,  and  rescind   administrative  rules  and
procedures in connection with the exercise of this Option. Any interpretation or
determination  by the  Board or the  Compensation  Committee  shall be final and
binding.


<PAGE>


The undersigned:

Dated This  4th    day of          (a) Acknowledges receipt of the fore-

  November            , 19 96  .   going option and understands that all
- ----------------------    -----
                                   rights and liabilities connected with

                                   this option are set forth in the Option

                                   and the Plan, (b) Acknowledges that as

Very truly yours,                  of the date of grant of this option, it
DIANON SYSTEMS, INC.
                                   sets forth the entire understanding
Duly authorized on
behalf of the                      between the undersigned optionee and
Board of Directors
                                   the Company regarding the acquisition of

                                   stock from the

Company and supersedes all         prior oral and written agreements on that

                                   subject with the

exception of the following         agreements only: (if none, so state)


                                                  /s/ Jeffrey L. Sklar
                                           ------------------------------------

                                   Address:        75 Francis St
                                           ------------------------------------
                                                    Boston, MA  02115
                                           ------------------------------------





                                                                   Exhibit 10.35


         THIS  AGREEMENT,  effective  this  3rd day of  December,  1996,  by and
between   DIANON   SYSTEMS,   INC.  (the   "COMPANY")  and  KEVIN  JOHNSON  (the
"EXECUTIVE").

                                WITNESSETH THAT:


         WHEREAS,  the  EXECUTIVE is employed by the COMPANY as President and is
an integral part of its  management  team and a key  participant in the decision
making process relative to short-term and long-term  planning and policy for the
COMPANY.


         WHEREAS,  as an inducement to commence his employment with the COMPANY,
the EXECUTIVE requested the COMPANY to make a personal loan to him;


         WHEREAS,  the COMPANY  wishes to encourage  the  EXECUTIVE to begin and
continue in his employment  with the COMPANY and the EXECUTIVE  wishes to remain
an employee of the COMPANY; and


         NOW,  THEREFORE,  it is hereby agreed by and between the parties hereto
as follows:

         1. Term of Loan Agreement

         This  Agreement  shall be  effective  as of the date above  written and
shall  continue  thereafter  until  the  first to  occur of (i) the  EXECUTIVE's
termination of employment with the COMPANY, or (ii) December 31, 2002.

         2. Loan Agreement

         (a) The COMPANY will advance to EXECUTIVE  one hundred  fifty  thousand
dollars ($150,000) on December 3, 1996

         (b)  EXECUTIVE  will pay  interest on the loan  annually at the rate of
6.6% per annum or the Internal Revenue Service standard,  whichever is less, and
the COMPANY  will pay  EXECUTIVE,  in addition to salary,  amounts  equal to the
interest paid by EXECUTIVE during his employment with the COMPANY.

         (c)  EXECUTIVE may repay all or any portion of the advance at any time.
If at any time during this Agreement the EXECUTIVE's employment with the COMPANY
is  terminated,  any unrepaid  portions of the advance  will become  immediately
repayable  on  the  date  the  EXECUTIVE's  employment  is  terminated,   unless
termination is by the COMPANY  without stated cause as described in Paragraph 10
of the  Employment  Agreement  entered by the  parties on May 3, 1996,  in which
case,  unrepaid  portions of the advance will become  payable one year after the
termination  date.  At the end of each full  month in the period  commencing  in
January, 1996 and ending December, 2002 in which EXECUTIVE's employment with the
COMPANY  continues  without  notice of intent to terminate  having been given by
EXECUTIVE or the COMPANY, the COMPANY shall forgive $2,500 of the advance.

         3. Income Tax Withholding and Reporting

         The COMPANY shall withhold all Federal,  State or other taxes as may be
required pursuant to any law or governmental  regulation or ruling.  The COMPANY
shall  report  as income to  EXECUTIVE  all  imputed  income  amounts  as may be
required pursuant to any Federal, State or other law or governmental  regulation
or ruling.

<PAGE>

         4. Wage Deduction Authorization

         EXECUTIVE agrees to execute any authorization necessary for the COMPANY
to achieve repayment through payroll deduction.

         5. No Right to Continue Employment; Employment at Will

         Nothing  contained in the Agreement  will confer upon the EXECUTIVE any
right to continued  employment  with the COMPANY,  nor shall limit the COMPANY's
right to terminate the EXECUTIVE's employment at will.

         6. Entire Understanding

         This Agreement  contains the entire  understanding  between the COMPANY
and the EXECUTIVE with respect to the loan  described  herein and supersedes any
prior agreement between the COMPANY and the EXECUTIVE.

         7. Severability

         If for any  reason,  any one or  more  of the  provisions  or part of a
provision  contained in this Agreement  shall be held to be invalid,  illegal or
unenforceable  in any respect,  such  invalidity,  illegality or  enforceability
shall not affect any other  provision or part of a provision  of this  Agreement
not held so invalid, illegal or unenforceable,  and each other provision or part
of a provision  shall to the full extent  consistent  with law  continue in full
force and effect.

         8. Binding Agreement

         This  Agreement  shall be binding upon,  and shall inure to the benefit
of, the EXECUTIVE and the COMPANY and their respective  permitted successors and
assigns.

         9. Modification

         This  Agreement may not be modified or amended  except by an instrument
in writing signed by the parties hereto.

         10. Headings of No Effect

         The paragraph  headings contained in this Agreement are included solely
for  convenience  of  reference  and shall not in any way affect the  meaning or
interpolation of any provisions of this Agreement.

         11. Governing Law

         This  Agreement  and its  validity,  interpretation,  performance,  and
enforcement  shall be governed by the laws of the State of  Connecticut  without
giving effect to the choice of law provisions in effect in such State.


<PAGE>

         IN WITNESS  WHEREOF,  the  COMPANY  has  caused  this  Agreement  to be
executed by its officer thereunto duly authorized,  and the EXECUTIVE has signed
this  Agreement,  all  effective  as of the date  first  above  written.


                                          DIANON SYSTEMS, INC.


                                          By:  /s/Richard A. Sandberg
                                               ----------------------------
                                                   Chairman


                                          KEVIN JOHNSON


                                          /s/Kevin Johnson
                                          ---------------------------------



                                                                   Exhibit 10.36
                              DIANON SYSTEMS, INC.

                                                            Grant No.

                           DIRECTOR STOCK OPTION GRANT


Optionee:               _____________      Total No. of Shares

Date of Grant:                             Exercise Price Per Share

Termination Date:


     DIANON  SYSTEMS,  INC.  (the  "Company")  has this day granted to you,  the
optionee  named  above,  an option  to  purchase  shares of common  stock of the
Company ("Common Stock")pursuant to the 1996 Stock Incentive Plan ("the Plan").

     The details of your option are as follows:

     1. The total number of shares subject to this option is as set forth above.
Subject to the limitations contained herein, this option shall be exercisable on
or after the date of the vesting of such option as follows:

<TABLE>
<CAPTION>
     Percentage of Shares              Date of Earliest Exercise (Vesting)
     --------------------              -----------------------------------
            <S>                              <C>
            10%                               91 days after Date of Grant
            10%                              182 days after Date of Grant
            10%                              273 days after Date of Grant
            10%                              364 days after Date of Grant
            10%                              455 days after Date of Grant
            10%                              546 days after Date of Grant
            10%                              637 days after Date of Grant
            10%                              728 days after Date of Grant
            10%                              819 days after Date of Grant
            10%                              910 days after Date of Grant
</TABLE>


     2. (a) The per share  exercise  price of this option is as set forth on the
face of this option grant

        (b) Payment of the exercise price is due in  full in cash upon  exercise
when the  aggregate  option  exercise  price for the shares  being  purchased is
$2,500 or less;  but when the  aggregate  exercise  price for the  shares  being
purchased  exceeds  $2,500,  you may elect to make payment of the exercise price
under one of the following alternatives:

               (i)  Payment  of the  exercise  price  in cash at the time of the
          exercise;

               (ii) (a) Payment of not less than 10% of the  aggregate  exercise
          price due at the time of  exercise  in cash,  (b) not less than 10% of
          said exercise price, plus simple interest at the lowest rate which, at
          the time of exercise,  will prevent any imputation of higher  interest
          under  Section 483 of the Internal  Revenue  Code,  per year after the
          time of  exercise,  with (c) final  payment  of the  remainder  of the
          exercise  price,  plus  interest,  due five  (5)  years  from  date of
          exercise,  provided that as a part of your written  notice of exercise
          you give notice of the election of this deferred payment  arrangement,
          and to  secure  the  payment  of the  deferred  purchase  price to the
          Company  hereunder,  which such  election  you tender to the Company a
          security agreement  satisfactory to the Company covering the purchased
          shares;


<PAGE>

               (iii) Provided that at the time of exercise the Company's  common
          stock is  publicly  traded and  quoted  regularly  in the Wall  Street
          Journal,  payment by delivery of shares of common stock of the Company
          which  you have  owned for at least six moths and which at the time of
          exercise  are  owned  by you  free and  clear  of any  liens,  claims,
          encumbrances or security interests, which common stock shall be valued
          (i) if listed on a national securities exchange or the Nasdaq national
          market,  at the average  closing  price for the ten (10)  trading days
          immediately  preceding  the date of exercise or (ii)  otherwise at the
          average of the closing bid and ask  quotations  published  in the Wall
          Street Journal for the ten (10) trading days immediately preceding the
          date of exercise; or

               (iv)  Payment in the form of any other legal  consideration  that
          may be acceptable to the Board of Directors of the Company in its sole
          discretion at the time of exercise.

     3. The minimum  number of shares  with  respect to which this option may be
exercised at any one time is one hundred (100), however, if the number of shares
subject to exercise is less than one hundred, the option must be exercised as to
all of such shares.

     4. The term of this option  commences on the date hereof and  terminates on
the date set forth on the face of this  option  grant.  Unless  you  resign as a
director  in which case the option will expire on the earlier of five years from
the date of your resignation or the Termination Date on page 1 hereto.

     5.  This  option  may  be  exercised,  to the  extent  specified  above  by
delivering  a  notice  of  exercise  together  with  the  exercise  price to the
Secretary of the Company,  or to such other person as the Company may designate,
during regular  business hours,  together with such additional  documents as the
Company may then require.

     6.  This  option  is not  transferable,  except  by will or by the  laws of
descent and distribution, and is exercisable during your life only by you.

     7. Any notices  provided  for in this option  shall be given in writing and
shall be deemed  effectively  given  upon  receipt  or,  in the case of  notices
delivered  by the  Company  to you,  five (5) days  after  deposit in the United
States mail, postage prepaid, addressed to you at the address specified below or
at such other address as you hereafter designates by written notice delivered to
the Company.

     8.  Whenever  shares are to be issued in  satisfaction  of this  option you
shall remit to the Company an amount sufficient to satisfy federal, state, local
or other  withholding  tax  requirements  if and to the extent  required  by law
(whether  so  required  to secure for the  Company an  otherwise  available  tax
deduction  or  otherwise)   prior  to  the  delivery  of  any   certificate   or
certifi-cates for such shares.

     9. In the  event  of any  merger,  reorganization,  consolidation,  sale of
substantially  all  assets,  recapitalization,   stock  dividend,  stock  split,
spin-off,  split-off,  distribution  of  assets  or other  change  in  corporate
structure  affecting the Common Stock, a substitution  of adjustment,  as may be
determined  to be  appropriate  by the Board of  Directors  or the  Compensation
Committee  of the  Board  ("the  Compensation  Committee")  shall be made in the
number, option price and kind of shares covered by this Option; provided however
that no such  adjustment  shall increase or decrease the aggregate  value of any
outstanding portion of this Option.

     10. This option is governed by the terms and  conditions  of the  Company's
1996 Stock  Incentive  Plan,  a copy of which is attached  hereto.  The Board of
Directors  and the  Compensation  Committee  reserve the right to interpret  the
provisions of this Option, make any necessary factual determinations, and adopt,
amend,  and rescind  administrative  rules and procedures in connection with the
exercise of this Option. Any interpretation or determination by the Board or the
Compensation Committee shall be final and binding.


<PAGE>


The undersigned:

Dated This      day of             (a) Acknowledges receipt of the fore-

              , 19   .             going option and understands that all
- --------------    ---
                                   rights and liabilities connected with

                                   this option are set forth in the Option

                                   and the Plan, (b) Acknowledges that as

Very truly yours,                  of the date of grant of this option, it
DIANON SYSTEMS, INC.
                                   sets forth the entire understanding
Duly authorized on
behalf of the                      between the undersigned optionee and
Board of Directors
                                   the Company regarding the acquisition of

                                   stock from the

Company and supersedes all         prior oral and written agreements on that

                                   subject with the

exception of the following
                                   agreements only: (if none, so state)



Attachment:                                  ---------------------------------
1996 Stock Incentive Plan
                                   Address:  ---------------------------------

                                             ---------------------------------






                                                                   Exhibit 10.37
                    AMENDMENT TO WARRANT CERTIFICATE NO. W-1

         AMENDMENT,  dated as of October 2, 1996 (the  "Amendment"),  to Warrant
Certificate  No. W-1 dated as of October  5, 1995 (the  "Warrant  Certificate"),
between DIANON Systems,  Inc., a Delaware corporation (the "Company"),  and G.S.
Beckwith Gilbert, or registered assigns ("Mr. Gilbert").

         WHEREAS, pursuant to a Stock and Warrant Purchase Agreement dated as of
October 4, 1995 among the Gilbert Family Trust, the G.S. Beckwith Gilbert I.R.A.
Contributory  Account,  G.S.  Beckwith  Gilbert and the Company  (the  "Purchase
Agreement"), the Company issued to the Purchasers (as defined therein) 1,000,000
shares of the  Company's  Common  Stock and the  Warrants  (as defined  therein)
evidenced by the Warrant Certificate.

         WHEREAS,  the Warrant  Certificate  specifies  the terms upon which the
Warrants may be exercised.

         WHEREAS,  the  Company  and Mr.  Gilbert  desire to amend  the  Warrant
Certificate  to change the last date on which  Warrants  can be  exercised at an
exercise  price  of  $5.00 to a date  subsequent  to the  vote of the  Company's
shareholders  on  approval  of a proposed  increase  in the voting  power of the
Purchasers  (as defined in the  Purchase  Agreement)  to 20% of the total voting
power of the Company's voting securities.

         WHEREAS, such amendment reflects the parties' intentions at the time of
issuance of the Warrant  Certificate  that Mr. Gilbert would have the benefit of
the knowledge of the outcome of such vote prior to the aforesaid exercise date.

         NOW, THEREFORE,  in consideration of the premises and mutual agreements
set  forth  in the  Purchase  Agreement  and this  Amendment,  the  receipt  and
sufficiency  of  which is  hereby  acknowledged,  the  parties  hereby  agree as
follows:

         1. The second  paragraph  of Section 1 of the  Warrant  Certificate  is
amended to read in its entirety as follows:


<PAGE>

                  "The registered  holder hereof shall have (a) the right at any
         time prior to  November  1, 1996 to elect that the  Expiration  Date of
         some or all of the Warrants  evidenced hereby shall be November 1, 1996
         rather  than  October  4,  1997 and (b) upon such  election,  the right
         thereafter  until 5:00 p.m., New York City time, on October 31, 1996 to
         exercise  such  Warrants at an exercise  price of $5.00  (increased  or
         decreased, as the case may be, to reflect the effect of each adjustment
         made,  at any  time  prior  to such  exchange,  to the  Exercise  Price
         pursuant to Section 2 as if the Exercise Price of this Warrant had been
         $5.00 since the date  hereof).  Upon such  election,  the Company shall
         extinguish,  as an  adjustment  to the  purchase  price  paid  for such
         Warrants,  for each such Warrant for which such election has been made,
         $0.37 of the  Principal  Amount (as  defined in the Note) due under the
         Note upon payment of the interest due on such  extinguished  amount for
         the  period  from  the date of this  Warrant  Certificate  through  and
         including  the  earlier  of the date of such  election  and  October 4,
         1996."

         2. This Amendment may be executed in  counterparts,  each ofwhich shall
be an original,  but all of which  together  shall  constitute  one and the same
instrument.

         IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be
duly executed as of the day and year first above written.


                                DIANON SYSTEMS, INC.


                                By:   /s/Richard A. Sandberg
                                   ----------------------------------
                                Name:  Richard A. Sandberg
                                Title: President, Chairman and Chief
                                       Executive Officer



                                G.S. Beckwith Gilbert


                                /s/ G. S. Beckwith Gilbert
                                --------------------------





                                                                   Exhibit 10.38
                                    AGREEMENT

         This Agreement made effective February 27, 1997 between DIANON SYSTEMS,
INC., a Connecticut corporation; and any successor thereto, hereinafter referred
to as the "Company," and RICHARD A. SANDBERG,  residing at 233 Brushy Ridge, New
Canaan, Connecticut 06840.

                                   WITNESSETH

         WHEREAS,  Richard A. Sandberg wishes to resign his position as Chairman
of the Board of Directors of the Company; and

         WHEREAS,  the Company  wishes to continue to employ Richard A. Sandberg
and Richard A. Sandberg wishes to accept such continued employment, in each case
for the purposes, on the terms, for the period and subject to the conditions set
forth below; and

         WHEREAS, the services that Richard A. Sandberg should render under this
Agreement to the Company are unique and valuable; and

         WHEREAS,  the  parties  desire to reduce  the terms and  conditions  of
Richard A. Sandberg's employment to writing; and

         WHEREAS,  the Compensation  Committee has approved and recommended that
the Company enter into this Agreement; and

         WHEREAS, based on the recommendation of the Compensation Committee, the
Board of Directors has ratified and approved this  Agreement and, in particular,
(i) has  ratified,  approved  and  confirmed  the  original  grant to Richard A.
Sandberg  of all options to  purchase  Company  stock held by him as of the date
hereof,  (ii) has approved the vesting in full of all options held by Richard A.
Sandberg as of the date hereof to the extent not previously  vested as set forth
in Section 2 hereof,  and (iii) has approved the purchase of all options held by
Richard A. Sandberg on terms set forth in Section 2 hereof.

         NOW,  THEREFORE,  in  consideration of the terms and conditions and the
mutual  covenants  contained  in this  Agreement,  the  Company  and  Richard A.
Sandberg hereby agree as follows:

         1. Resignation As Chairman

         Richard A. Sandberg  resigns as Chairman of the Board and as an officer
of the Company effective as of February 27, 1997.

         2. Stock Options

         All  options to buy  Company  stock held by Richard A.  Sandberg  as of
February 27, 1997,  (Options") to the extent not previously  vested will vest in
full  effective  February 27, 1997,  provided  that Richard A. Sandberg does not
revoke this Agreement pursuant to Section 24 of this Agreement.  A revocation by
Mr.  Sandberg of this Agreement  pursuant to Section 24 of This Agreement  shall
not affect (i) any Option (or portion  thereof) that was not vested  pursuant to
this  Section 2 and (ii) any  Option  that was  exercised  or sold by Richard A.
Sandberg prior to the date of such revocation.  Richard A. Sandberg may sell any
or all of the  options to the  Company  on or before May 28,  1997 for cash at a
price equal to (i) the number of shares of Company  stock covered by such Option
times (ii) the amount by which 10 7/8 exceeds the exercise price of such Option.
The  options  will  otherwise  be  exercisable  according  to the terms of their
initial grant(s).

         3. Employment As Consultant To The President

         The Company  hereby  employs  Richard A.  Sandberg as Consultant to the
President as of February 28, 1997 and Richard A.  Sandberg  hereby  accepts such
employment  upon the  terms and  conditions  set  forth in this  Agreement.  The
position  of  Consultant  to the  President  is not an officer  position  in the
Company.


<PAGE>

         4. Duties and Responsibilities

         Richard A.  Sandberg  will  perform  with  continuous  diligence  those
activities  assigned  to Richard  A.  Sandberg  by the  Company's  President  in
connection  with  special  projects  as the  President  may  from  time  to time
identify.  The parties  acknowledge  that the President  has full  discretion to
determine  the nature of all such  projects  and  location or locations at which
Richard A. Sandberg  shall perform  assigned  activities  under this  Agreement,
provided  that Richard A.  Sandberg  shall not be required to relocate  from his
residence in New Canaan, Connecticut.

         5. Term

         Richard A. Sandberg's  employment as Consultant to the President of the
Company will commence on February 28, 1997 and terminate  according to the terms
of Section 8 of this Agreement.

         6. Compensation

         The Company will compensate Richard A. Sandberg for his services during
the term of his  employment as Consultant to the President  under this Agreement
on a salaried  basis paid in  installments  at an  annualized  rate of $232,000.
Richard  A.  Sandberg  will  not   participate  in  any   management   incentive
compensation program maintained by the Company during the term of his employment
as Consultant to the President under this Agreement.

         7. Fringe Benefits

         During the term of his employment as Consultant to the President  under
this  Agreement,  the Company  will  provide  Richard A.  Sandberg  benefits and
emoluments as authorized for all other salaried Grade 19 management employees of
the Company as they may be modified from time to time by the Company,  including
at the time of the execution of this  Agreement,  health and medical  insurance,
life insurance, sick leave, vacation,  holidays, car allowance,  retirement plan
participation and stock purchase plan participation.

         8. Termination

         Richard A. Sandberg's employment as Special Consultant to the President
under  this  Agreement  will  terminate  on the  first  of any of the  following
occurrences:

         (a)      Richard A. Sandberg's death;

         (b)      Richard A,  Sandberg's  disability  for a period of 90 days or
                  more unless waived by the Board of Directors;

         (c)      mutual  agreement of the parties  reduced to writing signed by
                  both parties;

         (d)      voluntary resignation by Richard A. Sandberg;

         (e)      February 27, 1998,  absent renewal of this Agreement by mutual
                  agree-ment of the parties  memorialized in a writing signed by
                  both parties;

         (f)      termination by the Company for Cause,  i.e., gross negligence,
                  insub-ordination, or willful misconduct.

         9. Compensation After Termination

         (a) Richard A. Sandberg will not receive  compensation from the Company
after the  termination  of his  employment as Consultant to the President  under
this Agree-ment, other than unused vacation, except as described under paragraph
(b) of this Section of this Agreement, if applicable. Nothing in this Agreement,
however,  is intended to impair any rights  vested  under the law in any benefit
plan of the Company.

         (b) If Richard A. Sandberg's  employment as Consultant to the President
of the Company  terminates  because of the occurrence of the event  described in
paragraph (e) of Section 8 of this Agreement:
<PAGE>

         (i)      For a period of six months  beginning  with February 28, 1998,
                  the Company will pay Richard A. Sandberg  severance pay at his
                  rate of base pay on that date;

         (ii)     During said six month  period,  the Company  will pay the full
                  premium cost of medical  continuation  coverage for Richard A.
                  Sandberg  and/or his  dependents for any months in said period
                  during which Richard A.  Sandberg  and/or his  dependents  are
                  eligible and elect to continue such coverage;

         (iii)    During said six month period, the Company will provide Richard
                  A. Sandberg any Company car allowance  Richard A. Sandberg was
                  receiving on February 28, 1998; and

         (iv)     For  purposes  of stock  option  exercise,  a  termination  of
                  Richard A. Sandberg's  employment pursuant to paragraph (e) of
                  Section  8 of this  Agreement  shall be a  termination  by the
                  Company.

         10. Return of Property

         On the date  Richard A.  Sandberg's  employment  as  Consultant  to the
President terminates pursuant to Section 8 of this Agreement,  or at any earlier
point in time  when a  request  is made by the  Company  for  same,  Richard  A.
Sandberg  will turn over to the Company all notes,  reports,  memoranda,  books,
records,  chemicals,  devices and  documents,  whether in written,  typewritten,
computerized or any other form, which are in Richard A. Sandberg's possession or
under his control,  whether  prepared by him or others related to the Company or
relating to the business of the Company. Richard A. Sandberg will also return to
the  Company at the time his  employment  terminates,  or on an earlier  Company
request,  any Company keys,  parking card, credit card,  business cards or other
materials  related to this  employment  with the Company or the operation of the
Company.  Richard A. Sandberg will return to the Company any car this  Agreement
permits him to use for six months after the  termination of his employment  with
the Company at the conclusion of said six month period.

         11. Confidential Information

         Richard  A.  Sandberg  acknowledges  his  pre-existing  and  continuing
obligation not to use or disclose,  other than as authorized by the Company, any
trade  secrets or other  confidential  information  he has acquired  through his
association with the Company.

         12. Activity Against Company's Interest

         For the period of the  employment  of Richard A. Sandberg as Consultant
to the  President  of the  Company  and for a  period  of two  years  after  the
termination of that employment, Richard A. Sandberg will not engage or otherwise
be involved,  either directly or indirectly, in the recruitment of the Company's
employees or take any other action  ad-verse to the  management  of the Company.
Notwithstanding  the foregoing,  the parties agree that Richard A. Sandberg will
not violate his  obligations  under this  paragraph  by voting his shares in the
Company,  by voting on matters  before the Board of  Directors of the Company so
long as he  continues  to be a Director  of the  Company;  or by engaging in any
non-Company  business  activity  other  than  those he  commits to avoid in this
Agreement.

         13. Non Competition

         Richard A. Sandberg will not compete with any business  activity of the
Company  during his  employment  with the  Company and for a period of two years
after  the  termination  of that  employment.  Competition  includes  ownership,
management  (including serving as an officer or director),  operation,  control,
employment  or  consultation  of, by or to any business  organization  or entity
which  directly  or  indirectly  offers  the same or similar  services  as those
offered or  actively  being  developed  by the  Company  on the date  Richard A.
Sandberg's  employment  with the  Company  terminates.  The  obligation  in this
paragraph shall not be violated by Richard A. Sandberg's  ownership of shares of
stock in a  corporation  involved in such  activities  provided  such shares are
publicly  traded,  Richard A.  Sandberg  owns less than two percent of the total
number of issued and outstanding shares and Richard A. Sandberg is not otherwise
connected  with or active in, the  business  of such  corporation.  The  parties
recognize  that the Company's  business is carried on by telephone and from time
to time in person in each of the 50 States of the United  States of America  and
therefore that Richard A. Sandberg's  Agreement not to compete must apply in all
such 50 States.


<PAGE>

         14. Remedies For Breach Of Certain Covenants

         The parties  acknowledge  that because  Richard A. Sandberg has been an
officer and director of the Company and as such was and remains  conversant with
and had access to, the business,  affairs, records, trade secrets, customers and
customer  lists,  suppliers,   supplier  lists,  patents,   technical  know-how,
chemicals,  devices, sales or distribution agents and representatives,  sales or
distribution  agents and  representatives  lists,  and other  con-fidential  and
proprietary  information of the Company, his compliance with Sections 10, 11, 12
and 13 of this  Agreement  is  necessary  to  protect  the  goodwill  and  other
proprietary  interests  of the  Company  and a  breach  of  said  covenants  and
agreements in this Agreement will result in continuing and irreparable damage to
the Company for which there will be no adequate  remedy at law.  Therefore,  the
parties  acknowledge  that in the event of a breach  of  Richard  A.  Sandberg's
commitments in Sections 10, 11, 12 or 13 of this Agreement, the Company shall be
entitled,  if it so elects, to institute and prosecute  proceedings in any court
of competent  jurisdiction  either in law or in equity to obtain damages for any
breach of this Agreement and/or to enforce the specific  performance  thereof by
Richard A. Sandberg and/or to enjoin Richard A. Sandberg from retaining  Company
property, using confidential Company information,  competing with the Company or
soliciting or recruiting its employees or otherwise acting against the Company's
interests.

         15. Release And Waiver

         Richard   A.   Sandberg,   on  behalf  of   himself,   his   executors,
administrators  and assigns,  hereby releases the Company,  its affiliates,  and
their  respective  directors,   officers,  agents,  employees,   benefit  plans,
fiduciaries and  administrators  of such benefit plans and their  successors and
assigns  (hereinafter  "Released  Parties") from any and all claims or causes of
action of any kind,  other than vested  rights under  benefit plans or claims to
enforce  this  Agreement,  arising  on or  before  the  effective  date  of this
Agreement,  which  Richard A. Sandberg has, had or may have against any of them,
whether or not now known,  including but not limited to, any claims arising from
Richard  A.  Sandberg's  employment  or  officership  with the  Company,  or the
termination  thereof,  including  without  limitation  any claims  under the Age
Discrimination In Employment Act.

         16. Covenant Not To Sue

         Richard  A.  Sandberg  on  behalf of  himself,  his  heirs,  executors,
administrators  and assigns,  further  agrees never  directly or  indirectly  to
commence or prosecute, or to permit or advise to be commenced or prosecuted, any
action,  proceeding,  or charge  against  any  Released  Party,  in any state or
federal  court,  administrative  agency or  arbitral  forum with  respect to any
matter other than to enforce this Agreement,  whether or not now known,  for any
claim  whatsoever  (including but not limited to, any claim arising from Richard
A.  Sandberg's  employment or officership  with the Company,  or the termination
thereof) based upon any act,  transaction,  practice,  conduct, or omission that
occurred  prior to the effective  date of this  Agreement,  which he now has, or
claims  to  have,  or which at any  time  heretofore  had,  or which at any time
hereafter may have.  This covenant  includes but is not limited to, rights under
the Age  Discrimination in Employment Act or any other federal,  state, or local
laws prohibiting age, race, sex,  national origin,  religion,  or other forms of
discrimination,  claims for breach of contract or  promissory  estoppel or tort,
and claims  growing  out of any legal  restrictions  on the  Company's  right to
terminate its employees or officers.

         17. Non Admission

         The parties  recognize and agree that this Agreement does not and shall
not constitute an admission of liability or wrongdoing by Richard A. Sandberg or
the Company or its present or former affiliates,  directors,  officers,  agents,
employees.


         18. No Abridgment of Indemnification

         Nothing  in  this  Agreement  is  intended  to  limit  or  abridge  any
indemnification  the Company would otherwise  provide Richard A. Sandberg of and
from any claims based on his actions as an officer or director of the Company.



<PAGE>

         19. Intent To Be Enforced As Fully As Possible

         In the event  that any of the  terms or  provisions  of this  Agreement
shall  violate  any  statutory   provision  or  may  be  otherwise  unlawful  or
inoperative,  it is the intent of the parties that this Agreement operate and be
of  full  force  and  effect  insofar  as it does  not  violate  said  statutory
provisions or is otherwise  lawful and that this Agreement be carried out as far
as possible in a manner consistent with its intent.

         20. Litigation Costs

         In the event Richard A. Sandberg does not exercise his rights to revoke
this  Agreement  in  accordance  with  Section 24 and files a claim,  lawsuit or
complaint  against the Company in any court or governmental  agency with respect
to the claims released under this Agreement, Richard A. Sandberg shall be liable
for all costs and expenses including legal fees,  incurred by any Released Party
in defense of that action.

         21. Voluntariness

         Richard  A.  Sandberg   represents  that  he  has  carefully  read  and
completely  understands  this  Agreement  and  that  he has  entered  into  this
Agreement  voluntarily after having had an opportunity to consult with his legal
advisors,  which  he has  been  encouraged  to do in  writing  by  the  Company.
(Attachment A)

         22. Time To Review

         Richard A.  Sandberg  acknowledges  that he has been  advised he has 21
days to review the waivers and  releases  contained  in this  Agreement if he so
chooses.

         23. Adequacy Of Consideration

            Richard A. Sandberg  acknowledges that the commitments,  waivers and
releases he gives in this  Agreement are in exchange for valuable  consideration
to which he is not otherwise entitled.

         24. Revocation Option

         Richard A.  Sandberg  shall have seven (7) days after the  execution of
this  Agreement  to revoke the waivers and  releases in this  Agreement  and the
Agreement  shall not be  effective  unless and until  those  seven (7) days have
lapsed without Richard A. Sandberg so revoking.

         25. Entire Agreement

         This Agreement  constitutes the entire  Agreement of the parties on the
subject   matter   hereof  and   supersedes   any  and  all  prior   agreements,
understandings or commit-ments,  oral or written,  including without limitation,
the Executive  Severance  Agreement  between the Company and Richard A. Sandberg
dated March 9, 1989.


<PAGE>

         26. Governing Law

         This  Agreement  shall  be  governed  by  the  laws  of  the  State  of
Connecticut.

                                          RICHARD A. SANDBERG




      2/27/97                                  /s/Richard A. Sandberg
- --------------------------                -------------------------------------
Dated                                     Signature



                                          DIANON SYSTEMS, INC.




     2/27/97                                     /s/Kevin C. Johnson
- --------------------------                -------------------------------------
Dated                                     Signature




/29203

<PAGE>



                                                                    Attachment A




Mr. Richard A. Sandberg


Dear Richard:

The law  requires us to inform you in writing  that you should  consult a lawyer
before executing the Agreement we have proposed to become effective  between you
and the Company on February 27, 1997,  because it includes  releases and waivers
of potential rights.

Sincerely,

/s/Kevin C. Johnson

Kevin Johnson






                                                                    Exhibit 23.2



                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS



As independent  public  accountants,  we hereby consent to the  incorporation by
reference of (i) our report dated February 27, 1997,  incorporated  by reference
in DIANON  Systems,  Inc.'s Form 10-K for the year ended December 31, 1996, into
the previously filed Registration Statements Nos. 33-41226,  33-94176, 33-94178,
33-43673 and 333-18817 and (ii) our report dated March 15, 1996, incorporated by
reference  in DIANON  Systems,  Inc.  Form 10-K for the year ended  December 31,
1995, into the previously filed Registration Statements Nos. 33-41226, 33-94176,
33-94178 and 33-43673.





                               ARTHUR ANDERSEN LLP



Stamford, Connecticut
February 27, 1997



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<PERIOD-START>                  JAN-01-1996
<PERIOD-END>                    DEC-31-1996
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