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<TABLE> <S> <C>
<ARTICLE> 5
<CIK> 0000779282
<NAME> DIANON SYSTEMS, INC.
<MULTIPLIER> 1,000
<CURRENCY> U.S. Dollars
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> DEC-31-2000
<PERIOD-START> JAN-01-2000
<PERIOD-END> JUN-30-2000
<EXCHANGE-RATE> 1
<CASH> 11,102
<SECURITIES> 0
<RECEIVABLES> 22,006
<ALLOWANCES> 1,107
<INVENTORY> 1,454
<CURRENT-ASSETS> 35,050
<PP&E> 18,526
<DEPRECIATION> 12,975
<TOTAL-ASSETS> 54,863
<CURRENT-LIABILITIES> 7,565
<BONDS> 0
0
0
<COMMON> 72
<OTHER-SE> 42,454
<TOTAL-LIABILITY-AND-EQUITY> 54,863
<SALES> 46,505
<TOTAL-REVENUES> 46,505
<CGS> 26,580
<TOTAL-COSTS> 26,580
<OTHER-EXPENSES> 15,274
<LOSS-PROVISION> 0
<INTEREST-EXPENSE> 208
<INCOME-PRETAX> 4,766
<INCOME-TAX> 1,930
<INCOME-CONTINUING> 2,836
<DISCONTINUED> 0
<EXTRAORDINARY> 0
<CHANGES> 0
<NET-INCOME> 2,836
<EPS-BASIC> 0.40
<EPS-DILUTED> 0.37
</TABLE>
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