CRYOLIFE INC
DEF 14A, 1999-04-21
MISC HEALTH & ALLIED SERVICES, NEC
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                            SCHEDULE 14A INFORMATION
                  Proxy Statement Pursuant to Section 14(a) of
                       the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant [X]

Filed by a Party other than the Registrant [_]

Check the appropriate box:

[_]  Preliminary Proxy Statement            [ ] Confidential, for Use of the
[X]  Definitive Proxy Statement                 Commission Only (as permitted by
[_]  Definitive Additional Materials            Rule 14a-6(e)(2))
[_]  Soliciting Material Pursuant to
     (ss.)240.14a-11(c) or (ss.)240.14a-12

                                 CRYOLIFE, INC.
                (Name of Registrant as Specified In Its Charter)

                                       N/A
     (Name of Person(s) Filing Proxy Statement if other than the Registrant)


Payment of Filing Fee (Check the appropriate box):

[X]   No fee required.

[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

     1)   Title of each class of securities to which transaction applies:
     2)   Aggregate number of securities to which transaction applies:
     3)   Per unit  price  or other  underlying  value of  transaction  computed
          pursuant to Exchange  Act Rule 0-11 (Set forth the amount on which the
          filing fee is calculated and state how it was determined): 
     4)   Proposed maximum aggregate value of transaction: 
     5)   Total fee paid:

[_]   Fee paid previously with preliminary materials.

[_]   Check box if any part of the fee is offset as  provided  by  Exchange  Act
      Rule  0-11(a)(2)  and identify the filing for which the offsetting fee was
      paid  previously.  Identify the previous filing by registration  statement
      number, or the Form or Schedule and the date of its filing.

     1)   Amount Previously Paid:
     2)   Form, Schedule or Registration Statement No.:
     3)   Filing Party:
     4)   Date Filed:


<PAGE>



                      [Logo of CryoLife, Inc. Appears Here]
                          1655 ROBERTS BOULEVARD, N.W.
[LOGO]                      KENNESAW, GEORGIA 30144



                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

TO THE SHAREHOLDERS OF CRYOLIFE, INC.:

     NOTICE IS HEREBY GIVEN that the Annual Meeting of Shareholders of CRYOLIFE,
INC. will be held at the Marietta  Conference Center, 500 Powder Springs Street,
Marietta,  Georgia 30064,  on May 27, 1999 at 10:00 a.m.,  Atlanta time, for the
following purposes:

     1.   To elect five  directors  to serve  until the next  Annual  Meeting of
          Shareholders or until their successors are elected and have qualified.

     2.   To  transact  such other  business  as may  properly  come  before the
          meeting or any adjournments thereof.

      The proxy statement dated April 21, 1999 is attached.

     Only record holders of CryoLife's  $.01 par value common stock at the close
of business on April 9, 1999 will be eligible to vote at the meeting.

     Your  attendance at the annual  meeting is very much desired.  However,  if
there is any chance you may not be able to attend the meeting,  please  execute,
complete,  date and return the proxy in the enclosed envelope. If you attend the
meeting, you may revoke the proxy and vote in person.

                                    By Order of the Board of Directors:

                                    /s/ Steven G. Anderson


                                    STEVEN G. ANDERSON,
                                    Chairman of the Board and President

Date: April 21, 1999

     A copy of the Annual  Report of  CryoLife,  Inc.  for the fiscal year ended
December 31, 1998 containing financial statements is enclosed.


<PAGE>


                      [Logo of CryoLife, Inc. Appears Here]
                          1655 ROBERTS BOULEVARD, N.W.
[LOGO]                       KENNESAW, GEORGIA 30144

                                 PROXY STATEMENT
                       FOR ANNUAL MEETING OF SHAREHOLDERS

     This Proxy  Statement is  furnished  for the  solicitation  by the Board of
Directors of proxies for the Annual Meeting of Shareholders of CryoLife, Inc. to
be held on May 27, 1999, at 10:00 a.m., Atlanta time, at the Marietta Conference
Center, 500 Powder Springs Street, Marietta,  Georgia 30064. The sending in of a
signed  proxy will not affect a  shareholder's  right to attend the  meeting and
vote in person. A signed proxy may be revoked by the sending in of a timely, but
later dated,  signed proxy. Any shareholder giving a proxy may also revoke it at
any time before it is  exercised  by giving oral or written  notice to Ronald D.
McCall,  Secretary of CryoLife, or Ms. Suzanne Gabbert,  Assistant Secretary, at
the offices of CryoLife.  Oral notice may be delivered by telephone  call to Ms.
Gabbert, at the offices of CryoLife, at (770) 419-3355.

     Holders of record of CryoLife's $.01 par value common stock at the close of
business on April 9, 1999 will be eligible  to vote at the  meeting.  CryoLife's
stock  transfer  books will not be closed.  At the close of business on April 9,
1999,  CryoLife had  outstanding a total of 12,370,991  shares of $.01 par value
common  stock  (excluding  a total of 989,698  shares of treasury  stock held by
CryoLife,  which are not entitled to vote).  Each such share will be entitled to
one vote (non-cumulative) at the meeting.

     Other than the matters  set forth  herein,  management  is not aware of any
other  matters that may come before the meeting.  If any other  business  should
properly come before the meeting,  the persons named in the enclosed  proxy will
have  discretionary  authority to vote the shares  represented  by the effective
proxies and intend to vote them in accordance with their best judgment.

     This Proxy  Statement and the attached  proxy were first mailed to security
holders on behalf of  CryoLife  on or about April 21,  1999.  Properly  executed
proxies,  timely  returned,  will be  voted  and,  where  the  person  solicited
specifies  by means of a ballot a choice with  respect to any matter to be acted
upon at the meeting,  the shares will be voted as indicated by the  shareholder.
If the person  solicited  does not specify a choice with  respect to election of
directors,  the shares will be voted "FOR" management's nominees for election as
directors.  In addition to the  solicitation of proxies by the use of the mails,
directors  and officers of CryoLife may solicit  proxies on behalf of management
by  telephone,  telegram  and personal  interview.  Such persons will receive no
additional  compensation  for  their  solicitation   activities,   and  will  be
reimbursed only for their actual expenses in connection therewith.  The costs of
soliciting proxies will be borne by CryoLife.

VOTING PROCEDURES AND VOTE REQUIRED

     The Secretary of CryoLife, in consultation with the judges of election, who
will be employees of CryoLife's  transfer agent, shall determine the eligibility
of persons present at the Annual Meeting to vote and shall determine whether the
name  signed on each  proxy card  corresponds  to the name of a  shareholder  of
CryoLife.  The  Secretary,  based on such  consultation,  shall  also  determine
whether or not a quorum of the shares of CryoLife  (consisting  of a majority of
the votes  entitled  to be cast at the  Annual  Meeting)  exists  at the  Annual
Meeting.  Both  abstentions from voting and broker non-votes will be counted for
the  purpose  of  determining  the  presence  or  absence  of a  quorum  for the
transaction of business.

     Nominees for  election as  directors  will be elected by a plurality of the
votes cast by the  holders of shares  entitled  to vote in the  election.  Since
there are five directorships to be filled,  this means that the five individuals
receiving the most votes will be elected.  Abstentions and broker non-votes will
therefore not be relevant to the outcome.

     There are no rights of appraisal or similar dissenters' rights with respect
to any matter to be acted upon pursuant to this Proxy Statement.

<PAGE>

RECOMMENDATION OF THE BOARD OF DIRECTORS

     The Board of Directors of CryoLife  recommends a vote "FOR" the election of
each of the nominees named below for election as director.

ELECTION OF DIRECTORS

     The proxy holders intend to vote "FOR" election of the nominees named below
(who are  currently  members  of the Board) as  directors  of  CryoLife,  unless
otherwise  specified in the proxy.  Directors of CryoLife  elected at the Annual
Meeting  to be held on May 27,  1999 will  hold  office  until  the next  Annual
Meeting or until their successors are elected and qualified.

     Each of the nominees has consented to serve on the Board of  Directors,  if
elected.  Should any nominee for the office of director  become unable to accept
nomination  or election,  which is not  anticipated,  it is the intention of the
persons  named in the proxy,  unless  otherwise  specifically  instructed in the
proxy, to vote for the election of such other person as the Board may recommend.

     The  individuals  listed below as nominees for the Board of Directors  were
directors of CryoLife  during 1998.  The name and age of each  nominee,  and the
period  during  which such  person has served as a director,  together  with the
number of shares of  CryoLife's  common stock  beneficially  owned,  directly or
indirectly,  by  such  person  and  the  percentage  of  outstanding  shares  of
CryoLife's  common stock such ownership  represented at the close of business on
April 9, 1999  (according  to  information  received by  CryoLife)  is set forth
below:
<TABLE>
<CAPTION>
                                                                       Shares of                                    
                                                                     CryoLife Stock                                 
                                                                      Beneficially                Percentage of
                                      Service as                        Owned at                Outstanding Shares
        Name of Nominee                Director        Age          April 9, 1999(1)            of CryoLife Stock
- ---------------------------------    --------------   -------   -------------------------      ---------------------
<S>                                   <C>               <C>          <C>                             <C>    
Steven G. Anderson                    Since 1984        60           1,156,533(2)                     9.35%
Ronald C. Elkins, M.D.(4)(6)          Since 1994        62             101,700(3)                       *
Benjamin H. Gray(4)(6)                Since 1991        48             109,812(5)                       *
Virginia C. Lacy(4)(6)                Since 1997        57             443,586(7)                     3.59%
Ronald D. McCall, Esq.(6)             Since 1984        62             148,292(8)                       *
- ---------------
</TABLE>
*    Ownership  represents less than 1% of outstanding shares of CryoLife common
     stock.

(1)  Except as otherwise noted,  the nature of the beneficial  ownership for all
     shares is sole voting and investment power.
(2)  Includes  105,333  shares  held  of  record  by Ms.  Ann B.  Anderson,  Mr.
     Anderson's spouse. Also includes options to acquire 31,112 shares of common
     stock which are presently  exercisable or will become exercisable within 60
     days after the date of this Proxy Statement.
(3)  Includes  options  to  acquire  82,670  shares  of common  stock  which are
     presently  exercisable or will become  exercisable within 60 days after the
     date of this Proxy Statement.
(4)  Member of the Audit Committee.
(5)  Includes  options  to  acquire  103,500  shares of common  stock  which are
     presently  exercisable or will become  exercisable within 60 days after the
     date of this Proxy Statement.
(6)  Member of the Compensation Advisory Committee.
(7)  Includes  215,500 shares held as beneficiary of a trust, and 110,586 shares
     held as  beneficiary  of an IRA, of Ms. Lacy's  deceased  spouse.  Includes
     30,000  shares held as  administrator  of a pension plan.  Includes  63,500
     shares  subject to options which are presently  exercisable  or will become
     exercisable  within 60 days  after  the date of this  Proxy  Statement.  
(8)  Includes  10,000  shares of common stock owned of record by Ms.  Marilyn B.
     McCall,  Mr. McCall's spouse.  Includes options to acquire 83,500 shares of
     common stock which are  presently  exercisable  or will become  exercisable
     within 60 days after the date of this Proxy Statement.


                                       -2-
 
<PAGE>

     Steven G.  Anderson,  a  founder  of  CryoLife,  has  served as  CryoLife's
President,  Chief Executive Officer and Chairman of the Board of Directors since
its  inception.  Mr.  Anderson  has  more  than 30 years  of  experience  in the
implantable  medical device industry.  Prior to founding CryoLife,  Mr. Anderson
was Senior  Executive Vice President and Vice  President,  Marketing,  from 1976
until  1983 of  Intermedics,  Inc.  (now  Guidant  Corp.),  a  manufacturer  and
distributor of pacemakers and other medical devices.  Mr. Anderson  received his
BA from the University of Minnesota.

     Ronald C. Elkins,  MD, has served as a Director of CryoLife  since  January
1994.  Dr.  Elkins is Professor  and Vice Head of the  Department of Surgery and
Chief of Thoracic and  Cardiovascular  Surgery,  University  of Oklahoma  Health
Science  Center.  Dr. Elkins has been a physician at the Health  Science  Center
since 1971, and has held his present position since 1975.

     Benjamin H. Gray has served as a Director of CryoLife  since  January 1991.
Mr.  Gray is Chief  Financial  Officer of Columbia  Corporation,  an operator of
long-term care facilities.  Prior to joining  Columbia  Corporation in 1997, Mr.
Gray was a principal of Massey Burch Capital Corp.  and Vice President of Massey
Burch  Investment   Group,   Inc.,  a   Nashville-based   venture  capital  firm
specializing  in the health care industry.  Mr. Gray joined Massey Burch in 1987
and was  responsible  for  evaluating  and managing  various  investments in the
portfolio.  Mr. Gray was previously  with Chemical Bank of New York from 1973 to
1987.

     Virginia C. Lacy has served as a Director of CryoLife  since  August  1997.
Ms.  Lacy  is the  Administrator  of The  Jeanette  & John  Cruikshank  Memorial
Foundation,  which provides  assistance to those in need  throughout the greater
Chicago  area.  Ms.  Lacy has served as Chairman  of the Board of  Directors  of
Precision Devices Corporation, a distributor of pacemakers and other implantable
medical  devices,  since its founding in 1974.  Mrs. Lacy received her BA degree
from Northwestern University in 1963.

     Ronald D.  McCall,  Esq.  has served as a Director of  CryoLife  and as the
Secretary  and  Treasurer  of  CryoLife  since  January  1984.  From 1985 to the
present,  Mr. McCall has been the  proprietor of the law firm of Ronald  McCall,
Attorney  at Law,  based in Tampa,  Florida.  Mr.  McCall  was  admitted  to the
practice of law in Florida in 1961.  Mr.  McCall  received his BA and JD degrees
from the University of Florida.

                    INFORMATION ABOUT THE BOARD OF DIRECTORS
                           AND COMMITTEES OF THE BOARD

     Meetings of the Board of Directors--During  1998, there were seven meetings
of the Board of Directors.

     Director  Compensation--All  non-employee members of the Board of Directors
of  CryoLife  are paid  $1,500 for each Board  meeting  attended.  In  addition,
directors are reimbursed for expenses incurred in connection with their services
as a director. In December 1997, CryoLife adopted the CryoLife, Inc. Amended and
Restated Non-Employee Directors Stock Option Plan which plan replaced CryoLife's
1995 Non-Employee Directors Plan. Pursuant to this new plan, options to purchase
5,000 shares of common stock were  granted to each of Messrs.  Elkins,  Gray and
McCall  and  Ms.  Lacy   immediately   following  the  1998  Annual  Meeting  of
Shareholders.  In addition,  in May and December 1998,  each of these  directors
received options to purchase 10,000 shares pursuant to CryoLife's 1998 Long-Term
Incentive  Plan and a  special  grant  of  options  to  purchase  8,500  shares,
respectively, and agreed in May 1998 to have 28,000 options that were granted in
May 1996 canceled and replaced (which replacement  changed the exercise price of
such options from $16.75 to $17.125, the then current market price, and extended
the  exercisability  of such options by an additional 2 years).  The Amended and
Restated Non-Employee  Directors Stock Option Plan provides that an annual grant
will be made  each year  immediately  following  CryoLife's  Annual  Meeting  of
Shareholders  of an  option to  purchase  5,000  shares of common  stock to each
individual  elected,  reelected  or  continuing  as a  non-employee  director of
CryoLife.  All  options  granted  pursuant  to this new plan  are  granted  at a
purchase price equal to the last closing price of CryoLife's common stock on the
New York Stock  Exchange  immediately  prior to the grant of the option and vest
and become exercisable on the option's grant date. No option granted pursuant to
this new plan may be  exercised  later  than five  years  following  the date of
grant. In addition to the foregoing,  Dr. Elkins received  approximately $77,000
in consulting fees from CryoLife in 1998.

     Audit  Committee--CryoLife's Audit Committee consists of three non-employee
directors:  Dr. Elkins, Mr. Gray and Ms. Lacy. The Audit Committee met two times
in 1998.  The Audit  Committee  reviews the general scope of  CryoLife's  annual
audit and the nature of  services to be  performed  for  CryoLife in  connection
therewith,  acting as liaison between the Board of Directors and the independent

                                       -3-

<PAGE>

auditors.  The Audit  Committee  also  formulates  and reviews  various  company
policies,  including those relating to accounting practices and internal control
systems of  CryoLife.  In  addition,  the Audit  Committee  is  responsible  for
reviewing and monitoring the performance by CryoLife's  independent auditors and
for recommending the engagement or discharge of CryoLife's independent auditors.

     Compensation  Advisory  Committee--CryoLife  has  a  Compensation  Advisory
Committee currently consisting of four non-employee  directors:  Mr. McCall, Ms.
Lacy, Dr. Elkins and Mr. Gray.  The  Compensation  Advisory  Committee met three
times in 1998. The Compensation Advisory Committee is responsible for evaluating
the  performance  of  officers  and  setting  the  annual  compensation  for all
officers,  including  the  salary  and the  compensation  package  of  executive
officers.  A portion of the  compensation  package  includes a bonus award.  The
Compensation  Advisory  Committee  also  administers  CryoLife's  benefit plans,
except that the  Compensation  Advisory  Sub-Committee  approves grants of stock
options to executive  officers under CryoLife's  benefit plans.  Currently,  the
Compensation Advisory Sub-Committee consists of two non-employee directors:  Ms.
Lacy and Mr. Gray. The Compensation  Advisory  Sub-Committee  met three times in
1998.

     Nominating   Committee--CryoLife   does  not  have  a  standing  nominating
committee of the Board of Directors.

     During 1998,  no director  attended  fewer than 75% of the aggregate of the
total  number of  meetings  of the Board of  Directors  and the total  number of
meetings held by all committees of the Board on which he or she served.

     Notwithstanding  anything to the  contrary  set forth in any of  CryoLife's
filings under the Securities Act of 1933, as amended, or the Securities Exchange
Act of  1934,  as  amended,  that  might  incorporate  other  CryoLife  filings,
including this Proxy  Statement,  in whole or in part, the following  Report and
Performance Graph shall not be incorporated by reference into any such filings.

                REPORT OF THE COMPENSATION ADVISORY COMMITTEE ON
                             EXECUTIVE COMPENSATION

OVERVIEW

     The Compensation  Advisory Committee of the Board of Directors of CryoLife,
Inc. is composed of  non-employee  directors  and approves the  compensation  of
CryoLife's  executive  officers at least  annually.  The Committee  believes the
actions  of  executive  officers  of  CryoLife  have a  profound  impact  on the
short-term and long-term  profitability  of CryoLife.  Therefore,  the Committee
gives significant attention to the design of CryoLife's compensation package.

     CryoLife's  compensation  package consists of three parts and is relatively
simple in design.  The three primary parts are a base salary,  a cash bonus, and
stock-based incentive  compensation.  No significant perquisites are provided to
executive officers.

BASE SALARY

     The Committee  believes it is important  for  executive  officers and other
employees  of  CryoLife to receive  acceptable  salaries  so that  CryoLife  can
recruit and retain the talent it needs.  For several  years,  the  Committee has
obtained a salary  survey  report.  This survey,  which is entitled the "Radford
Salary  Survey  for U.S.  Biotech  Companies,"  contains  information  regarding
salaries paid to various biotech  executives in the United States. The Committee
reviews this salary survey  primarily for  information  regarding  salaries,  as
opposed  to bonus and stock  incentive  information.  In setting  salaries,  the
Committee takes into consideration the individual employee's performance, length
of service to CryoLife,  and the information provided by the Radford Survey. The
Committee  seeks to set  compensation  at levels which are reasonable  under the
circumstances  and near the  midrange  for U.S.  biotech  companies.  For  1998,
salaries for executive officers were raised by 7.3%, on the average, as compared
to 1997.  The range of  increases  was from 5% to 12%.  The base salary for each
executive  officer  is set on a  subjective  basis,  bearing  in mind an overall
impression of that executive's  relative skills,  experience and contribution to
CryoLife. The Committee does not attempt to address the relative weight assigned


                                       -4-

<PAGE>

to the various  factors,  which are  evaluated on a subjective  overall basis by
each individual member of the Committee.  Salaries of all executive officers are
reviewed  annually by the  Committee.  In accordance  with this  procedure,  the
Committee consults with Mr. Anderson,  the President and Chief Executive Officer
of CryoLife,  and an appropriate range of base salary,  bonus, and stock options
is subjectively considered, based upon the range of compensation received by the
other executive officers and the requirements of the particular  positions to be
filled.  The Chief Executive Officer  negotiates with candidates for employment,
subject to acceptance and  ratification  by the Committee,  and this  negotiated
base salary is reflected in each candidate's employment agreement.

CASH BONUSES

     Cash bonuses are the next component of executive officer  compensation.  In
determining  the  amount  to be paid  as  bonuses  to  executive  officers,  the
Compensation  Advisory  Committee  considers  the  performance  of  CryoLife  in
reaching  goals  for  increased  revenues  and  pre-tax  profit  as  well as the
performance  of each executive  officer.  For 1998,  the  Compensation  Advisory
Committee  based its  decision  that  bonuses  should be awarded  to  CryoLife's
executive  officers  upon its  subjective  determination  that  CryoLife's  1998
increases in total revenues and pre-tax profits  justified the granting thereof.
The amount of the bonus paid to  individual  executive  officers was  determined
based upon the Committee's  subjective  analysis of the performance of each such
officer.  Excluding  the cash bonus paid to the Chief  Executive  Officer,  1998
executive officer bonuses ranged from $30,000 to $42,000 and were paid in 1999.

STOCK-BASED INCENTIVES

     Stock-based  incentives have been a supplemental  component of compensation
for  CryoLife's  executive  officers,  and certain  other  employees,  since the
formation of CryoLife.  CryoLife  adopted formal incentive stock option plans in
1984,  1989,  1993 and  1998.  CryoLife  has also made  grants of  non-qualified
options  under an informal  stock option  program.  The  Sub-Committee  approves
grants of stock options to executive officers under CryoLife's option plans.

     Historically,  grants made by CryoLife have  generally  vested at a rate of
20% per year and have had a term of five and one-half years.  These options also
usually expire upon termination of employment, except in the event of disability
or  death,  in which  case the term of the  option  may  continue  for some time
thereafter.

     The  Sub-Committee  believes that CryoLife's  stock option program has been
effective  in  focusing  attention  on  shareholder  value  since the gain to be
realized by executive officers upon exercise of options will change as the stock
price changes.  The Sub-Committee also believes that the long-term nature of the
options  encourages  CryoLife's  executive  officers  to remain  with  CryoLife.
Finally,  the  Sub-Committee  has found it appropriate to grant options to newly
employed  executive  officers in order to  encourage  such  officers to identify
promptly with  CryoLife's  goal of increased  shareholder  value.  The number of
shares to be granted is established  utilizing the procedure  described above at
"--Base Salary." The Sub-Committee  subjectively determines the number of shares
to be  granted  based on its  analysis  of the  number  which  would  provide an
adequate  incentive  to the new  executive  officer  to accept a  position  with
CryoLife.

     In general,  following  initial  employment,  the  granting of  stock-based
incentives  to  executive  officers is  considered  by the  Sub-Committee  to be
justified  when  CryoLife's  revenues and earnings,  coupled with the individual
executive's  performance,  warrant supplemental  compensation in addition to the
salary and bonus paid with  respect to a given  year.  Each of these  factors is
weighed  subjectively by Sub-Committee  members in determining  whether or not a
stock-based  incentive  should be granted,  and such  incentives are not granted
routinely.  Except for  stock-based  incentives  granted to the Chief  Executive
Officer,  no other executive officer was granted a stock-based  incentive during
fiscal  1998.  The  Committee  thinks  it  unlikely  that  any  participants  in
CryoLife's stock plans will, in the foreseeable future,  receive in excess of $1
million in aggregate  compensation (the maximum amount for which an employer may
claim a  compensation  deduction  pursuant  to  Section  162(m) of the  Internal
Revenue Code of 1986 unless certain performance-related  compensation exemptions
are met) during any fiscal year, and has therefore determined that CryoLife will
not take any  affirmative  action at this time to meet the  requirements of such
exemptions.

COMPENSATION OF THE CHIEF EXECUTIVE OFFICER

     The  Committee  fixed the 1998  salary of Mr.  Steven  G.  Anderson,  Chief
Executive  Officer of  CryoLife,  at $385,000.  Mr.  Anderson was awarded a cash
bonus of $175,000 for his  performance in 1998. This bonus reflected an increase

                                       -5-

<PAGE>


of $40,000 over the 1997 bonus. This exhibits the philosophy of the Committee as
set forth at "--Base  Salary" and "--Cash  Bonuses" above. In 1998, Mr. Anderson
was granted  stock options to purchase  18,500  shares of common stock,  thereby
providing  him with the same option  shares  granted to the other  directors  of
CryoLife.  The  Committee  and  Sub-Committee  believe the  compensation  of Mr.
Anderson,  a founder of CryoLife,  reflects their  subjective  opinions that Mr.
Anderson has provided  superlative  leadership and fulfilled the functions of an
executive officer of CryoLife at the highest level.

     In  addition,  on May 21, 1998,  the  Compensation  Advisory  Sub-Committee
analyzed the difference  between the exercise prices of the 40,000 stock options
granted to Mr. Anderson on May 16, 1996 versus the then-current  market price of
CryoLife's  common  stock  and  determined  that,  because  of the  $1.30  price
differential,  the options  were not  providing  the desired  incentive  for the
performance   for  CryoLife's   Chief  Executive   Officer.   Pursuant  to  this
determination,  the  Compensation  Advisory  Sub-Committee  canceled  all of the
options granted to Mr. Anderson in May 1996 and exchanged them for an equivalent
number of options  with an exercise  price equal to the closing  market price of
CryoLife's common stock as of May 21, 1998. See "Ten-Year Option/Sar Repricings"
table below.

CONCLUSION

     The Committee and  Sub-Committee  believe that the mix of a cash salary and
bonuses  and a long-term  stock  incentive  compensation  program  represents  a
balance that has motivated and will continue to motivate  CryoLife's  management
team to produce the best results possible given overall economic  conditions and
the difficulty of predicting CryoLife's performance in the short term.

                                  COMPENSATION ADVISORY
                                        COMMITTEE:

                                        RONALD D. McCALL, CHAIRMAN
                                        VIRGINIA C. LACY
                                        RONALD C. ELKINS, M.D.
                                        BENJAMIN H. GRAY

                                  COMPENSATION ADVISORY
                                        SUB-COMMITTEE:

                                        VIRGINIA C. LACY
                                        BENJAMIN H. GRAY

                                       -6-

<PAGE>


                                PERFORMANCE GRAPH

     Set forth  below is a  line-graph  presentation  comparing  the  cumulative
shareholder  return on CryoLife's  common stock,  on an indexed  basis,  against
cumulative total returns of the Nasdaq Stock Market (U.S. Companies) and a "peer
group" selected by management of CryoLife. The peer group selected for inclusion
in this Proxy Statement includes Advanced Tissue Sciences, Inc., Osteotech, Inc.
and LifeCell  Corporation.  Each of these companies has securities traded on the
Nasdaq Stock Market.  Advanced  Tissue and Osteotech were selected  because they
had been utilized as a basis for comparison with CryoLife in reports by analysts
for  each  of  the  two  co-managers  of  CryoLife's  initial  public  offering.
Management  selected LifeCell to be included in the peer group based on the fact
that LifeCell, a developer of tissue engineered  products,  is also a biomedical
company. The returns for the peer group were weighted according to each issuer's
market  capitalization.  The Performance  Graph shows total return on investment
for the period beginning January 1, 1994 and ending December 31, 1998.

                                 [GRAPH OMITTED]
<TABLE>
<CAPTION>

                  VALUE OF $100 INVESTED ON JANUARY 1, 1994 AT:

                         1/1/94        12/31/94      12/31/95       12/31/96      12/31/97      12/31/98
                       -----------    -----------   ------------   -----------   -----------    --------
<S>                    <C>            <C>           <C>            <C>           <C>            <C>
CRYOLIFE               $ 100.00       $  104.00     $  248.00      $  400.00     $  436.00      $  380.00
PEER GROUP             $ 100.00       $   88.55     $  112.55      $  108.31     $  183.54      $  138.76
NASDAQ MARKET          $ 100.00       $  104.99     $  136.18      $  169.23     $  207.00      $  291.96
</TABLE>


                 Total return assumes reinvestment of dividends.


                                      -7-

<PAGE>

                             EXECUTIVE COMPENSATION

     The following table sets forth the compensation paid or accrued by CryoLife
to  CryoLife's  Chief  Executive  Officer  and the four other most  highly  paid
executive officers of CryoLife in 1998 (the "Named Executives"). The information
presented is for the years ended December 31, 1998, 1997 and 1996.

                           SUMMARY COMPENSATION TABLE

<TABLE>
<CAPTION>
                                                                                    Long-Term
                                                        Annual Compensation        Compensation
                                                      -------------------------    --------------
                                                                                    Securities                      
                                                                                    Underlying         All Other
              Name and                                  Salary       Bonus         Options/SARs       Compensation
         Principal Position               Year         ($) (1)      ($)(2)            (#) (3)           ($) (5)
- --------------------------------------    --------    -------------------------    --------------    ---------------
<S>                                       <C>       <C>             <C>                  <C>         <C>    
Steven G. Anderson                        1998      $    385,000    $  175,000            58,500     $  27,361
    Chairman of the Board of              1997           345,000       135,000             8,000        34,750
    Directors, President and Chief        1996           300,000       100,000            40,000        28,125
    Executive Officer

Kirby S. Black, PhD                       1998           122,850        40,000                 0         9,011
    Vice President, Research and          1997           117,000        30,000                 0         7,896
    Development                           1996           106,000        20,000                 0             0

Albert E. Heacox, PhD                     1998           152,250        42,000                 0         7,894
    Vice President, Laboratory            1997           145,000        40,000                 0         8,625
    Operations                            1996           132,000        40,000                 0         7,190

Edwin B. Cordell, Jr.                     1998           131,250        42,000                 0         3,268
    Vice President and Chief              1997           125,000        30,000            10,000         3,098
    Financial Officer                     1996           112,000        30,000                 0         4,668

James C. Vander Wyk, PhD. (4)             1998           131,250        40,000                 0         2,503
    Vice President, Regulatory            1997           125,000        30,000                 0         1,871
    Affairs and Quality Assurance         1996            97,856        10,000            30,000             0
</TABLE>
- -----------------  

(1)  Includes  base  salary  earned  by the  Named  Executives  for the  periods
     presented or, for executives hired during the periods  presented,  from the
     date  of  hire  to  the  end  of  the  applicable  period.   Also  includes
     compensation  deferred  under  CryoLife's  401(k)  plan,  and amounts  such
     officers  elected  to  apply  to  CryoLife's  supplemental  life  insurance
     program.  Amounts for perquisites and other personal  benefits  extended to
     the Named  Executives  are less than the  lesser of  $50,000  or 10% of the
     total of annual salary and bonus of such Named Executive.
(2)  Includes bonuses earned by the Named  Executives for the periods  presented
     or, for executives  hired during the periods,  for the period from the date
     of hire to the end of the applicable year.
(3)  During  the  periods  presented,  the only form of  long-term  compensation
     utilized by CryoLife has been the grant of stock options.  CryoLife has not
     awarded  restricted  stock  or  stock  appreciation  rights,  or  made  any
     long-term incentive payouts. Accordingly, the columns for "Restricted Stock
     Award(s)" and "Long Term Incentive Payouts" have been omitted.
(4)  Dr. Vander Wyk was first employed by CryoLife in February 1996.
(5)  Since the inception of CryoLife's  401(k) plan,  CryoLife has been matching
     contributions  to the plan  subject  to  certain  limitations  and  vesting
     requirements.  In 1992,  CryoLife adopted its  supplemental  life insurance
     program for certain executive officers. The following table sets forth, for
     each of the Named Executives, the amount of CryoLife's contributions to the
     401(k) plan and the supplemental life insurance program:

                                      -8-

<PAGE>
<TABLE>
<CAPTION>

                                    1998                                   1997                                     1996
                     -----------------------------------   -----------------------------------    ----------------------------------
                                          SUPPLEMENTAL                          SUPPLEMENTAL                            SUPPLEMENTAL
                                              LIFE                                  LIFE                                    LIFE
                              401(K)        INSURANCE                401(K)       INSURANCE                   401(K)      INSURANCE
                     TOTAL  CONTRIBUTION     PROGRAM       TOTAL  CONTRIBUTION     PROGRAM        TOTAL    CONTRIBUTION    PROGRAM
                     ------ ------------  --------------   ------ ------------- -----------       -----    ------------- -----------
<S>                 <C>        <C>        <C>             <C>       <C>          <C>               <C>        <C>          <C>      
Steven G. Anderson  $27,361   $4,973      $22,388         $34,759   $4,750       $30,000           $28,125     $4,750      $23,375
Kirby S. Black,       9,011    2,547        6,464           7,896    2,421         5,475               ---        ---          ---
Ph.D.                                                     
Albert E. Heacox,     7,894    3,743        4,151           8,625    3,625         5,000             7,190      3,300        3,890
PhD
Edwin B.              3,268    3,268            0           3,098    3,098             0             4,668      4,668          ---
Cordell, Jr. 
James C. Vander       2,503    2,503            0           1,871    1,871             0               ---        ---          ---
Wyk, PhD
</TABLE>

     Grant of Options.  During 1998,  options were granted to Steven G. Anderson
in recognition of his  performance.  No options were granted to any of the other
Named  Executives  during 1998.  No stock  appreciation  rights (SARs) have been
granted by CryoLife.  The following table sets forth  information  regarding the
grant of options in 1998:

                  OPTION/SAR GRANTS IN LAST FISCAL YEAR (1998)
<TABLE>
<CAPTION>
                                                                                                                  
                                                                                                                    
                                                                                                                    
                                                                                              Potential Realizable
                                                       % of Total                               Value at Assumed
                                        Number of      Options/SARs                             Annual Rates of
                                        Securities     Granted to                              Appreciation for
                                        Underlying     Employees     Exercise                     Option Term
                                        Options/SARs   in Fiscal      Price     Expiration   -----------------------
                Name                    Granted (#)       Year       ($/Sh)(4)   Date(5)      5%($)         10%($)
 ------------------------------------   -----------    -----------   --------   ----------   -----------------------
<S>                                     <C>              <C>      <C>           <C>          <C>          <C>
 Steven G. Anderson..............       40,000(1)        22.66%   $   17.13     05-21-08     430,919      1,092,032

                                        10,000(2)        5.66%        17.13     05-21-08     107,730        273,008

                                         8,500(3)        4.82%        12.00     12-18-08      64,147        162,562
- -------------
</TABLE>
(1)  The  options  vest and become  exercisable  on a  cumulative  basis on each
     anniversary  following  the grant date as follows:  50 shares on the second
     anniversary,  4,100  shares on the third  anniversary,  5,800 shares on the
     fourth  through  ninth   anniversaries   and  1,000  shares  on  the  tenth
     anniversary,  with 50 shares  immediately  vesting on the grant  date.  The
     options were originally  granted in May 1996 and were exchanged for options
     with an  exercise  price equal to the closing  market  price of  CryoLife's
     common stock on May 21, 1998. See "Ten-Year  Option/SAR  Repricings"  table
     below.
(2)  The options vest and become  exercisable  on January 1, 2007 and January 1,
     2008 in the amount of 4,800 shares and 5,200 shares, respectively.
(3)  The option vests on January 1, 2008.
(4)  The  exercise  price was fixed as the closing  market  price on the date of
     grant.
(5)  Options  are  subject  to  earlier  termination  in  the  event  of  death,
     disability, retirement, or termination of employment.

     Options Exercised. The following table sets forth information regarding the
exercise  of  options  in 1998  and the  number  of  options  held by the  Named
Executives as listed in the Summary  Compensation Table,  including the value of
unexercised  in-the-money options, as of December 31, 1998. The closing price of
CryoLife's  common stock on December 31, 1998 used to calculate  such values was
$11.875 per share.

           AGGREGATED OPTION/SAR EXERCISES IN LAST FISCAL YEAR (1998)
         AND FISCAL YEAR-END OPTION/SAR VALUES (AS OF DECEMBER 31, 1998)
                                                        
<TABLE>
<CAPTION>
                                                       
                                                           
                                                           
                                                             NUMBER OF SECURITIES            VALUE OF UNEXERCISED             
                                                            UNDERLYING UNEXERCISED               IN-THE-MONEY                       
                                SHARES                           OPTIONS/SARs                    OPTIONS/SARs                       
                              ACQUIRED ON      VALUE            AT YEAR END (#)                 AT YEAR END ($)                     
                               EXERCISE       REALIZED      ------------------------     ------------------------------        
           NAME                   (#)           ($)         EXERCISABLE  UNEXERCISABLE   EXERCISABLE      UNEXERCISABLE
- ---------------------------   -----------     --------      ----------   -------------   -----------      -------------
<S>                                <C>     <C>                 <C>           <C>       <C>              <C>
Steven G. Anderson........         32,988  $    264,728        23,062        94,450    $   124,226      $      286,840
Kirby S. Black, PhD.......              0             0        18,000        12,000        112,500              75,000
Albert E. Heacox, PhD.....              0             0        18,000        12,000         78,840              52,560
Edwin B. Cordell, Jr......          6,000        50,280         8,000        14,000         50,280              50,280
James C. Vander Wyk, PhD..              0             0        12,000        18,000         40,560              60,840
</TABLE>
                                      -9-

<PAGE>


     Option  Repricing.  CryoLife repriced stock options held by Mr. Anderson in
1998.  The  following  table sets forth the  number of stock  options  that were
repriced in 1998.


                         TEN-YEAR OPTION/SAR REPRICINGS
<TABLE>
<CAPTION>
                                                                                                         Length of
                                          Number of                                                      Original
                                          Securities        Market Price    Exercise                     Option Term
                                          Underlying        of Stock at     Price at         New         Remaining at
                                          Options/SARs      Time of         Time of          Exercise    Date of
                                          Repriced or       Repricing or    Repricing or     Price       Repricing or
Name                          Date        Amended (#)       Amendment ($)   Amendment ($)    ($)         Amendment
- --------------------------    --------    -------------     ------------    ------------     -------     -------------
<S>                           <C>         <C>               <C>             <C>              <C>         <C>
Steven G. Anderson...         5-21-98     40,000            $17.13          $18.43           $17.13      3 years
</TABLE>


     Long-Term  Incentive  Plans.  On December 19, 1997,  the Board of Directors
adopted,  subject to approval  of  shareholders,  the  CryoLife  1998  Long-Term
Incentive  Plan.  The 1998  Long-Term  Incentive  Plan provides for the grant of
options,  stock appreciation  rights and other awards to acquire up to a maximum
of 300,000 shares of common stock, subject to certain  adjustments.  As of April
9, 1999, options for 210,500 shares were outstanding and options for zero shares
had been  exercised.  Options may be granted under the 1998 Long-Term  Incentive
Plan to  employees,  officers or  directors of and  consultants  and advisors to
CryoLife and its  subsidiaries.  CryoLife  estimates  that, as of April 9, 1999,
approximately 403 employees (including officers) and three non-officer directors
of CryoLife were eligible to participate  in the Long-Term 1998 Incentive  Plan.
Unless  sooner  terminated  by the  Board,  the 1998  Long-Term  Incentive  Plan
terminates in May 2008. These stock options also usually expire upon termination
of  employment  or  shortly  thereafter.  In the event of a "change  of  control
transaction"  as defined in the 1998 Long-Term  Incentive  Plan,  limitations on
exercisability of stock options owned by executive officers shall be waived, and
the limitations on exercisability of stock options owned by others may be waived
in the discretion of the Compensation Advisory Committee.

     CryoLife Amended and Restated Non-Employee Directors Stock Option Plan. The
CryoLife Amended and Restated Non-Employee  Directors Stock Option Plan provides
for the grant of  options  to  non-employee  directors  of  CryoLife.  This plan
provides  for the grant of options to acquire up to a maximum of 175,000  shares
of common  stock.  At each Annual  Meeting of  Shareholders,  each  non-employee
director  elected,  re-elected  or  continuing  as a  non-employee  director  of
CryoLife  receives an annual  grant of options to purchase  5,000  shares on the
first  business  day after such Annual  Meeting,  which  options  shall vest and
become  exercisable  on the date of grant.  Except as set forth  below,  options
granted under this plan are not  transferable  other than by will or the laws of
descent and  distribution.  Notwithstanding  the  foregoing,  the  optionee  may
transfer  the option for no  consideration  to or for the benefit of a member of
the optionee's  immediate family (including,  without limitation,  to a trust or
IRA) subject to such limits as the Board may establish, and the transferee shall
remain  subject to all the terms and  conditions  that were  applicable  to such
option prior to the transfer. Upon the death of a non-employee director, options
which were  exercisable on the date of death are exercisable by his or her legal
representatives  or heirs, but in no event may the option be exercised after the
last day on which it could have been exercised by the non-employee  director. As
of December 31,  1998,  options for 20,000  shares had been  granted  under this
plan.

     Employment Agreements. CryoLife has entered into employment agreements with
each of the Named  Executives.  Except for Mr. Anderson's  agreement,  and other
than with respect to position  specific terms,  such as duties of employment and
compensation,  these  employment  agreements  are  substantially  identical  and
provide that  employment may be terminated by either party with or without cause
upon  30  days'  written  notice  to the  other.  The  agreements  automatically
terminate upon death. Each employee is required to devote his full and exclusive
time and attention to his employment  duties, and CryoLife reserves the right to
change the nature and scope of those duties. The agreement conditions employment
and continued employment upon the employee's signing CryoLife's standard Secrecy
and Noncompete Agreement.

                                      -10-

<PAGE>

     A new employment  agreement with Mr.  Anderson was negotiated in 1999 for a
term of five years,  which replaces a similar  contract  negotiated in 1995. The
Compensation  Advisory  Committee  approved the  inclusion of a provision in the
agreement  pursuant to which Ms. Ann B.  Anderson,  the spouse of Mr.  Anderson,
would be provided with health care coverage  throughout  her life. The agreement
provides that either party may terminate Mr. Anderson's employment by giving 180
days' written notice to the other. The termination may be with or without cause.
In the event CryoLife terminates  employment without cause, Mr. Anderson will be
entitled to be paid for the remainder of his term or for two years, whichever is
greater.  If the termination is with cause, after the 180 days' notice period no
additional compensation is due.

     Compensation Advisory Committee Interlocks and Insider  Participation.  The
following  four  directors  serve  on the  Compensation  Advisory  Committee  of
CryoLife's  Board of Directors:  Mr. McCall,  Ms. Lacy, Dr. Elkins and Mr. Gray.
Mr. McCall has been Secretary and Treasurer of CryoLife since 1984. CryoLife has
engaged  Ronald  McCall,  P.A.,  a law  firm of  which  Mr.  McCall  is the sole
shareholder,  to perform legal services on an ongoing basis.  For the year ended
December 31, 1998, CryoLife paid Ronald McCall, P.A.  approximately  $68,000 for
such legal services (including expense reimbursements). Management believes that
these  services were provided on terms no less  favorable to CryoLife than terms
available from unrelated parties for comparable services. See "Information about
the Board of  Directors  and  Committees  of the Board - Director  Compensation"
regarding consulting fees paid by CryoLife to Dr. Elkins during fiscal 1998.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

     Section 16(a) of the  Securities  Exchange Act of 1934 requires  CryoLife's
executive  officers and directors and persons who beneficially own more than 10%
of CryoLife's  stock to file initial reports of ownership and reports of changes
in ownership with the Securities and Exchange  Commission.  Executive  officers,
directors and greater than 10% beneficial owners are required by SEC regulations
to furnish CryoLife with copies of all Section 16(a) forms they file.

     Based  solely on its review of copies of forms  received  by it pursuant to
Section 16(a) of the Securities Exchange Act of 1934 or written  representations
from reporting persons, CryoLife believes that with respect to 1998, all Section
16(a) filing requirements  applicable to its executive  officers,  directors and
greater than 10% beneficial  owners were complied with,  except that David Fronk
filed one late report on Form 3.


                                      -11-

<PAGE>



<PAGE>


             OWNERSHIP OF PRINCIPAL SHAREHOLDERS, NAMED EXECUTIVES,
                 AND EXECUTIVE OFFICERS AND DIRECTORS AS A GROUP


     The name and address of each person or entity who owned  beneficially 5% or
more of the  outstanding  shares of common  stock of  CryoLife on April 9, 1999,
together  with the  number of shares  owned and the  percentage  of  outstanding
shares that ownership  represents is set forth in the following table. The table
also shows  information  concerning  beneficial  ownership  by each of the Named
Executives  (See  "Executive  Compensation")  and by all directors and executive
officers as a group. The number of shares beneficially owned is determined under
the rules of the SEC,  and the  information  is not  necessarily  indicative  of
beneficial  ownership  for any  other  purpose.  Under  such  rules,  beneficial
ownership  includes  any  shares as to which the  individual  has sole or shared
voting power or investment  power and also any shares which the  individual  has
the right to acquire  within 60 days after the date hereof  through the exercise
of any stock option or other right. Unless otherwise indicated,  each person has
sole investment and voting powers (or shares such powers with his or her spouse)
with respect to the shares set forth in the following table:
<TABLE>
<CAPTION>
                                                                                Percentage of
                                                      Number of Shares of        Outstanding
                                                        Cryolife Stock            Shares of
                         Beneficial Owner             Beneficially Owned        Cryolife Stock
- ---------------------------------------------------  ----------------------    -----------------
<S>                                                        <C>                       <C>
Steven G. Anderson.................................         1,156,533 (1)            9.35%
FMR Corp...........................................           657,100 (2)            5.31%
Kirby S. Black, PhD................................            18,758 (3)             *
Albert E. Heacox, PhD..............................            79,000 (4)             *
Edwin B. Cordell, Jr...............................            23,300 (5)             *
James C. Vander Wyk, PhD ..........................            18,000 (6)             *
All current Directors and Executive Officers
     as a group (11 persons).......................         2,124,364 (7)           17.17%
- ------------------
</TABLE>
*    Ownership represents less than 1% of outstanding CryoLife common stock.

(1)  Includes  105,333  shares  held  of  record  by Ms.  Ann B.  Anderson,  Mr.
     Anderson's spouse. Also includes 31,112 shares subject to options which are
     presently  exercisable or will become  exercisable within 60 days after the
     date of this Proxy Statement. The business address for Mr. Anderson is: c/o
     CryoLife, Inc., 1655 Roberts Blvd., N.W., Kennesaw, Georgia 30144.
(2)  The  business  address  of FMR Corp.  is:  82  Devonshire  Street,  Boston,
     Massachusetts 02109.
(3)  Includes  18,000  shares  subject  to options  which are  either  presently
     exercisable  or will  become  exercisable  within 60 days after the date of
     this  Proxy  Statement.  Also  includes  270  shares  held  by Dr.  Black's
     children.
(4)  Includes  18,000  shares  subject  to options  which are  either  presently
     exercisable  or will  become  exercisable  within 60 days after the date of
     this Proxy Statement.
(5)  Includes  2,300  shares in a trading  account as to which Mr.  Cordell  has
     signature  authority  and 8,000 shares  subject to options which are either
     presently  exercisable or will become  exercisable within 60 days after the
     date of this Proxy Statement.
(6)  Includes  18,000  shares  subject  to options  which are  either  presently
     exercisable  or will  become  exercisable  within 60 days after the date of
     this Proxy Statement.
(7)  See "Election of Directors" for information as to the beneficial  ownership
     of shares  attributed  to directors.  Includes  449,282  shares  subject to
     options which are presently  exercisable or will become  exercisable within
     60 days after the date of this Proxy Statement.  Includes 2,300 shares held
     in a trading  account  as to which Mr.  Cordell  has  signature  authority.
     Includes  270  shares  held as trustee by an  executive  officer.  Includes
     215,500 shares held as  beneficiary of a trust,  and 110,586 shares held as
     beneficiary  of an IRA, of Ms.  Lacy's  deceased  spouse.  Includes  30,000
     shares held as  administrator  of a pension plan.  Includes  115,333 shares
     held of record by the spouses of executive officers and Directors.

                                      -12-
<PAGE>


                         INDEPENDENT PUBLIC ACCOUNTANTS

     The  accounting  firm of  Ernst &  Young  LLP  have  been  the  independent
certified  public  accountants of CryoLife since 1996.  Approval or selection of
the independent certified public accountants of CryoLife is not submitted to the
Annual  Meeting  of  Shareholders.  The  Board  of  Directors  of  CryoLife  has
historically  selected the independent  certified public accountants of CryoLife
with the advice of the Audit Committee,  and the Board believes that it would be
to the detriment of CryoLife and its shareholders for there to be any impediment
(such as selection or  ratification by the  shareholders)  to its exercising its
judgment to select  CryoLife's  independent  certified public  accountants or to
remove them if, in its opinion, such removal is in the best interest of CryoLife
and its shareholders.

     It is anticipated that a representative from the accounting firm of Ernst &
Young LLP will be  present  at the  annual  meeting  of  shareholders  to answer
questions and make a statement if the representative desires to do so.

                              SHAREHOLDER PROPOSALS

     Appropriate   proposals  of  shareholders   intended  to  be  presented  at
CryoLife's  2000  Annual  Meeting  of   Shareholders   pursuant  to  Rule  14a-8
promulgated  under  the  Securities  Exchange  Act of 1934 must be  received  by
CryoLife by December 19, 1999 for  inclusion in its proxy  statement and form of
proxy relating to that meeting. In addition, all shareholder proposals submitted
outside of the  shareholder  proposal rules  promulgated  pursuant to Rule 14a-8
under the Exchange  Act must be received by CryoLife by March 4, 2000,  in order
to be considered timely. If such shareholder  proposals are not timely received,
proxy holders will have  discretionary  voting authority with regard to any such
shareholder proposals which may come before the 2000 Annual Meeting. If the date
of the next annual  meeting is advanced or delayed by more than 30 calendar days
from the date of the  annual  meeting to which  this  Proxy  Statement  relates,
CryoLife shall, in a timely manner,  inform its shareholders of the change,  and
the date by which proposals of shareholders must be received.


     UPON THE WRITTEN REQUEST OF ANY RECORD OR BENEFICIAL  OWNER OF COMMON STOCK
OF CRYOLIFE WHOSE PROXY WAS SOLICITED IN CONNECTION WITH THE 1999 ANNUAL MEETING
OF SHAREHOLDERS, CRYOLIFE WILL FURNISH SUCH OWNER, WITHOUT CHARGE, A COPY OF ITS
ANNUAL REPORT ON FORM 10-K WITHOUT  EXHIBITS FOR ITS FISCAL YEAR ENDED  DECEMBER
31,  1998.  REQUEST  FOR A COPY OF SUCH  ANNUAL  REPORT ON FORM  10-K  SHOULD BE
ADDRESSED TO SUZANNE GABBERT, ASSISTANT SECRETARY,  CRYOLIFE, INC., 1655 ROBERTS
BOULEVARD, N.W., KENNESAW, GEORGIA 30144.

     IT IS IMPORTANT THAT PROXIES BE RETURNED PROMPTLY.  SHAREHOLDERS WHO DO NOT
EXPECT TO ATTEND THE  MEETING IN PERSON  ARE URGED TO SIGN,  COMPLETE,  DATE AND
RETURN  THE PROXY CARD IN THE  ENCLOSED  ENVELOPE,  TO WHICH NO POSTAGE  NEED BE
AFFIXED.

                               By Order of the Board of Directors

                               /s/ Steven G. Anderson

                                   STEVEN G. ANDERSON, Chairman
                                   of the Board, President and Chief
Dated: April 21, 1999              Executive Officer

                                      




<PAGE>
                                    Annex 1

                                 CRYOLIFE, INC.
               PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
                  FOR USE AT THE ANNUAL MEETING ON MAY 27, 1999

         The  undersigned  shareholder  hereby  appoints  STEVEN G. ANDERSON and
RONALD D. McCALL,  or any of them,  with full power of  substitution,  to act as
proxy for, and to vote the stock of, the  undersigned  at the Annual  Meeting of
Shareholders of CRYOLIFE, INC.
to be held on May 27, 1999, and any adjournments thereof.

         The  undersigned  acknowledges  receipt of Notice of the Annual Meeting
and Proxy  Statement,  each dated April 21, 1999,  and grants  authority to said
proxies,  or their substitutes,  and ratifies and confirms all that said proxies
may lawfully do in the  undersigned's  name,  place and stead.  The  undersigned
instructs said proxies to vote as indicated below and on the reverse hereof.

                         (continued on the reverse side)

<PAGE>
                              

                        Please date, sign and mail your
                      proxy card back as soon as possible!

                        Annual Meeting of Shareholders of
                                 CRYOLIFE, INC.
                                  May 27, 1999
                                       at
                           Marietta Conference Center
                            500 Powder Springs Street
                                Marietta, Georgia
                                   10:00 A.M.

                              FOLD AND DETACH HERE
<TABLE>
<CAPTION>
<S>                <C>                           <C>                       <C>   
                   FOR election of the           REFRAIN FROM             Nominees:   Steven G. Anderson
                   individuals set forth at      VOTING FOR election                  Ronald C. Elkins, M.D.
                   right (except as marked       of the nominees set                  Benjamin H. Gray
                   to the contrary)              forth at right                       Virginia C. Lacy
                                                                                      Ronald D. McCall, Esq.
1. ELECTION OF
   DIRECTORS:             |_|                         |_|

</TABLE>

     (INSTRUCTIONS: To withhold authority to vote for any individual nominee(s),
write that person's name on the space provided below.)

               __________________________________________________


2. Upon such other matters as may properly come before the meeting.

THE PROXIES  SHALL VOTE AS SPECIFIED  ABOVE,  OR IF NO  DIRECTION IS MADE,  THIS
PROXY WILL BE VOTED FOR EACH OF THE LISTED NOMINEES.

PLEASE VOTE,  SIGN,  DATE AND RETURN THIS PROXY CARD PROMPTLY USING THE ENCLOSED
ENVELOPE.

Please  enter your Social  Security  Number or Federal  Employer  Identification
Number here:___________________________________


                                            
Signature________________  Date________  Signature________________  Date________
                                         
NOTE:(Shareholders  should sign exactly as name appears on stock. Where there is
     more than one owner each should sign. Executors,  Administrators,  Trustees
     and others signing in a representative capacity should so indicate.)



                                      



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