February 26, 1998
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549-1004
Attn: Filing Desk - Stop 1-4
RE: Insured Municipals Income Trust and Investors' Quality
Tax-Exempt Trust, Multi-Series 16
File No. 33-02238 CIK #785799
Ladies/Gentlemen:
In accordance with the provisions of Rule 497(j) of
Regulation C under the Securities Act of 1933 (the
"Securities Act") this letter serves to certify that the most
recent amendment to the Post-Effective of the subject
Registration Statement on Form S-6 for the above captioned
Trust does not differ from that which would have been filed
pursuant to Rule 497(b) of the Securities Act. Amendment No.
11 to the Post-Effective, which was the most recent amendment
to the Post-Effective of the Registration Statement, was
filed electronically with the Commission on February 23,
1998.
Very truly yours,
VAN KAMPEN AMERICAN CAPITAL DISTRIBUTORS, INC.
