SENETEK PLC /ENG/
NT 10-K/A, 1998-04-07
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                          COMMISSION FILE NUMBER
                                                                         0-14691
                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                 AMENDMENT NO. 1
                                  FORM 12B-25/A

                           NOTIFICATION OF LATE FILING

(Check  One):  X__Form 10-K and Form 10-KSB  ___Form 20-F  ___Form 11-K 
               ___Form 10-Q ___Form N-SAR

For Period Ended: December 31, 1997

[   ] Transition Report on Form 10-K

[   ] Transition Report on Form 20-F

[   ] Transition Report on Form 11-K

[   ] Transition Report on Form 10-Q

[   ] Transition Report on Form N-SAR

For the Transition Period Ended: _______________________

                   NOTHING IN THIS FORM SHALL BE CONSTRUED TO IMPLY
                   THAT THE COMMISSION HAS VERIFIED ANY
                   INFORMATION CONTAINED HEREIN.

If the notification relates to a portion of the filing checked above, identify
the items(s) to which the notification relates:
- --------------------------------------------------------------------------------

PART I - REGISTRANT INFORMATION

SENETEK PLC 
- -------------------------
Full Name of Registrant:


- -------------------------
Former Name if Applicable


23 PALACE STREET
- -------------------------
Address of Principal Executive Office (Street and Number)


LONDON, UNITED KINGDOM SWIE SHW
- -------------------------------
City, Country and Zip Code




<PAGE>



PART II - RULES 12b-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

     (a)  The reasons described in reasonable detail in Part III of this form
- ----      could not be eliminated without unreasonable effort or expense;

 X   (b)  The subject annual report, semi-annual report, transition report on
- ----      Form 10-K, Form 20-F, 11-K, Form N-SAR, or portion thereof, will be
          filed on or before the fifteenth calendar day following the prescribed
          due date; or the subject quarterly report of transition report on Form
          10-Q, or portion thereof will be filed on or before the fifth calendar
          day following the prescribed due date; and

 X   (c)  The accountant's statement or other exhibit required by Rule 12b-25(c)
- ----      has been attached if applicable.

PART III - NARRATIVE

State below in reasonable detail the reasons why the Form 10-K, 11-K, 10-Q,
N-SAR, or the transition report or portion thereof, could not be filed within
the prescribed time period.

     The Registrant amends the report filed on March 30, 1998 as follows:

     The Registrant is a UK plc based in London, England with a small corporate
     staff. During 1997, the company suffered disruption in its corporate
     accounting function responsible for the production of US SEC reporting and
     US GAAP matters. The company's chief accountant died, and the Finance
     Director and Company Secretary suffered a stroke and has not been able to
     resume full time work. Accordingly, the company has suffered from a lack of
     critical resource, particularly on US GAAP and reporting issues, and has
     been unable to complete its 10-K and financial statements, and consequently
     the company's auditors have been unable to complete their audit.

PART IV - OTHER INFORMATION

(1)  Name and telephone number of person to contact in regard to this
     notification

         PAUL LOGAN                011-44-171               828-4800 
         ----------                ----------               -------- 
           (Name)             (Country and City Code)    (Telephone Number)

(2)  Have all other periodic reports required under Section 13 or 15(d) of the
     Securities Exchange Act of 1934 or Section 30 of the Investment Company Act
     of 1940 during the preceding 12 months or for such shorter period that the
     registrant was required to file such report(s) been filed? If answer is no,
     identify report(s). : Yes X  No
                              ---   ----
(3)  Is it anticipated that any significant change in results of operations from
     the corresponding period for the last fiscal year will be reflected by the
     earnings statements to be included in the subject report or portion
     thereof? : Yes X    No
                   ---     ---


If so, attach an explanation of the anticipated change, both narratively and
quantitatively, and, if appropriate, state the reasons why a reasonable estimate
of the results cannot be made.

Management believes that the anticipated change in the results of operations
(losses) are primarily the result of (i) research and development costs which
have more than doubled, (ii) increased general and administration spending to 
expand the corporate infrastructure, particularly in enhancing manufacturing
capacity in order to support future product demand; (iii) the recognition of
compensation expense for employee stock option plans, in accordance with APB25.




<PAGE>





                                  SENETEK PLC.
                                  ------------
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.

Date     APRIL 3, 1998                By: /S/ ANTHONY J. CATALDO
         -------------                   ------------------------
                                         Anthony J. Cataldo, President

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly authorized representative. The name and title of the person
signing the form shall be typed or printed beneath the signature. If the
statement is signed on behalf of the registrant by an authorized representative
(other than an executive officer), evidence of the representatives authority to
sign on behalf of the registrant shall be filed with the form.

INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL CRIMINAL
VIOLATIONS (SEE 18 U.S.C. 1001).











PRICE WATERHOUSE              NO. 1 LONDON BRIDGE      TELEPHONE: 0171-939-3000
                              LONDON SE1 9QL           TELEX: 884657 PRIWAT G
                                                       FACSIMILE:  0171-403-5265




April 3, 1998


Private And Confidential

PA Logan, Esq.
Senetek PLC
23 Palace Street
London
SW1E 5HW

Dear Paul:

You have furnished us with a copy of your "Notification Of Late Filing" on Form
12B-25 dated 3 April 1998.

We are in agreement with the comments under Part III of the Form with respect to
the reasons why we are unable to furnish our report on the financial statements
of Senetek PLC on or before the date the Form 10-K of Senetek PLC for the year
ended 31 December 1997 is required to be filed.

Yours sincerely,

/S/ Price Waterhouse

PRICE WATERHOUSE







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