<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
STATEMENT OF ASSETS AND LIABILITIES, STATEMENT OF OPERATIONS, AND STATE-
MENT OF CHANGES IN NET ASSETS FOUND ON PAGES 108 THROUGH 131 OF THE FORTIS
SERIES FUND, INC. SEMI-ANNUAL SHAREHOLDER REPORT.
</LEGEND>
<CIK> 0000790558
<NAME> FORTIS SERIES FUND, INC.
<SERIES>
<NUMBER> 19
<NAME> AMERICAN LEADERS SERIES
<MULTIPLIER> 1
<S> <C>
<PERIOD-TYPE> 2-MOS
<FISCAL-YEAR-END> DEC-31-2000
<PERIOD-START> MAY-01-2000
<PERIOD-END> JUN-30-2000
<INVESTMENTS-AT-COST> 5,416,346
<INVESTMENTS-AT-VALUE> 5,461,251
<RECEIVABLES> 12,918
<ASSETS-OTHER> 0
<OTHER-ITEMS-ASSETS> 3,636
<TOTAL-ASSETS> 5,477,805
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 5,435
<TOTAL-LIABILITIES> 5,435
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 5,404,788
<SHARES-COMMON-STOCK> 539,328
<SHARES-COMMON-PRIOR> 0
<ACCUMULATED-NII-CURRENT> 14,133
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 8,544
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 44,905
<NET-ASSETS> 5,472,370
<DIVIDEND-INCOME> 18,462
<INTEREST-INCOME> 9,484
<OTHER-INCOME> 0
<EXPENSES-NET> (13,813)
<NET-INVESTMENT-INCOME> 14,133
<REALIZED-GAINS-CURRENT> 8,544
<APPREC-INCREASE-CURRENT> 44,905
<NET-CHANGE-FROM-OPS> 67,582
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 0
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 539,496
<NUMBER-OF-SHARES-REDEEMED> (168)
<SHARES-REINVESTED> 0
<NET-CHANGE-IN-ASSETS> 5,472,370
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 9,529
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 16,220
<AVERAGE-NET-ASSETS> 5,292,795
<PER-SHARE-NAV-BEGIN> 10.35
<PER-SHARE-NII> 0.01
<PER-SHARE-GAIN-APPREC> (0.21)
<PER-SHARE-DIVIDEND> 0
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.15
<EXPENSE-RATIO> 1.25<F1><F2>
<FN>
<F1>ANNUALIZED.
<F2>FORTIS ADVISERS HAS VOLUNTARILY UNDERTAKEN TO LIMIT ANNUAL EXPENSES FOR
AMERICAN LEADERS SERIES (EXCLUSIVE OF INTEREST, TAXES, BROKERAGE COMMISSION
AND NON-RECURRING EXTRAORDINARY CHARGES AND EXPENSES) TO 1.25% OF THE
AVERAGE NET ASSETS. FOR THE PERIOD, HAD THE WAIVER AND REIMBURSMENT OF
EXPENSES NOT BEEN IN EFFECT, THE RATIO OF EXPENSES TO AVERAGE DAILY NET
ASSETS WOULD HAVE BEEN 1.54%.
</FN>
</TABLE>
