BIO REFERENCE LABORATORIES INC
10-K, 2000-01-31
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C.  20549


                                    FORM 10-K

  (Mark One)
    |X|ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
              SECURITIES EXCHANGE ACT OF 1934

            For the fiscal year ended  October 31, 1999
                                       ----------------

                                       OR

    |_|TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
               SECURITIES EXCHANGE ACT OF 1934

        For the Transition period from                 to
                                       ---------------

                         Commission file number 0-15266
                                                -------

                        BIO-REFERENCE LABORATORIES, INC.
                        --------------------------------
             (Exact name of registrant as specified in its charter)

      New Jersey                                             22-2405059
      ----------                                             ----------
(State or other jurisdiction of                            (I.R.S. Employer
incorporation or organization)                             Identification No.)

481 Edward H. Ross Drive, Elmwood Park, New Jersey              07407
- --------------------------------------------------              -----
(Address of principal executive offices)                     (Zip Code)

Issuer's telephone number, including area code  201-791-2600
                                                ------------

Securities registered pursuant to Section 12(b) of the Act:

                                                  Name of each exchange on which
      Title of Class                                             registered
      --------------                              -------------------------
         None                                                   None

Securities registered pursuant to Section 12(g) of the Act:

                          Common Stock, $.01 par value
                          ----------------------------
                                (Title of Class)

      Indicate by check mark  whether the  registrant  (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days. Yes X No .

      Indicate by check mark if disclosure of delinquent filers pursuant to Item
405 of Regulation S-K is not contained herein, and will not be contained, to the
best of the issuer's  knowledge,  in definitive proxy or information  statements
incorporated  by reference in Part III of this Form 10-K or in any  amendment to
this Form 10-K. [ ]

      On January 21,  2000,  the  aggregate  market value of the voting stock of
Bio-Reference  Laboratories,  Inc.  (consisting of Common Stock, $.01 par value)
held by  non-affiliates  of the Issuer was approximately $ 18,354,000 based upon
the last sales price for such Common Stock on said date in the  over-the-counter
market as reported  by the NASDAQ  Small Cap  System.  On such date,  there were
8,100,920 shares of Common Stock of the Issuer outstanding.


<PAGE>



                                     PART I

Item. 1 - Business
- ------------------

      Bio-Reference  Laboratories,   Inc.,  "Bio-Reference"  or  the  "Company,"
operates a clinical laboratory servicing the greater New York metropolitan area.
Bio-Reference offers a comprehensive list of chemical diagnostic tests including
blood  and urine  analysis,  blood  chemistry,  hematology  services,  serology,
radioimmuno analysis,  toxicology (including drug screening), pap smears, tissue
pathology (biopsies) and other tissue analyses. Bio-Reference holds the required
Federal and state  licenses  necessary to permit its operation of its processing
facilities  in New Jersey and New York State and to permit its  servicing of its
clients in Connecticut,  Florida,  Louisiana,  Maryland,  New Jersey,  New York,
Pennsylvania, Texas and Virginia. Bio-Reference markets its services directly to
physicians, hospitals, clinics, and other health facilities.

      Subsequent  to the  close  of  fiscal  1998,  the  Company  commenced  the
expansion  of its business  from an almost  exclusively  transaction  processing
operation  (i.e.  clinical  laboratory  testing)  into  health  information  and
connectivity areas by seeking to expand its business base through utilization of
its physician  network and  marketing  staff.  During  fiscal 1999,  the Company
entered into the e-health marketplace through the opening of its own drug screen
website,  "DRUGSCREENLAB.com"  and  subsequently  acquired an  Internet  website
"DoctorNY.com"  serving the New York  metropolitan  area and hosting a number of
existing physician  websites.  To date,  virtually all of the Company's revenues
have been derived from its clinical laboratory testing.

      The United States market for clinical  laboratory  testing is estimated to
generate approximately $30 billion in annual revenues.
      -  50% of these revenues are generated by hospital laboratories
      -  50% of these  revenues are generated by  independent  laboratories  and
         physician office laboratories.

      Bio-Reference  was incorporated  under the laws of the State of New Jersey
in December 1981 under the name "Med-Mobile,  Inc." Its initial primary business
was to provide mobile medical  examinations.  This business was  discontinued in
June 1989.  Since  February 1987,  the Company's  primary  business has been the
operation of a clinical  laboratory located in northern New Jersey servicing the
greater New York metropolitan area. The Company expanded its laboratory services
through the March 1988  acquisition of Cytology and Pathology  Associates,  Inc.
and relocated all of its laboratory  operations to its facility in Elmwood Park,
New Jersey. The Company changed its name to Bio-Reference Laboratories,  Inc. in
November 1989.  Bio-Reference has expanded its laboratory  testing  capabilities
and its customer base through  internal growth as well as through the completion
of a series of acquisitions of the businesses of other testing laboratories.

      The Company's  executive  offices are located at 481 Edward H. Ross Drive,
Elmwood Park, New Jersey 07407. Its telephone number is (201) 791-2600.

Developments Since the Beginning of Fiscal 1999

      On November 23, 1998,  the Company's  outstanding  publicly  owned Class A
Redeemable Warrants and Class B Redeemable Warrants expired by their terms.

      In June  1999,  the  Company  acquired  a software  license  enabling  the
grouping of medical  claims data  analysis and has  proceeded to develop its own
proprietary  algorithms  and  enhancements  to the  licensed  software  so as to
include laboratory and prescription  data. The Company is currently  negotiating
with two ERISA funds which cover more than 60,000 lives for access to certain of
their claims information in order to conduct beta site testing of its analytical
tools and  programs.  In the event  such beta site  testing is  successful,  the
Company anticipates offering such software tools and programs to customers.

      In June  1999,  in  connection  with the  release  of its  second  quarter
operating  results,  Bio-Reference  announced  the  write-off of an  approximate
$900,000  balance of unamortized  goodwill related to its 1997 purchase of Smith
Kline  Beecham's  end stage  renal  dialysis  business  and the  increase in the
allowance of approximately $2,000,000 for accounts receivable, all of which were
attributable to renal dialysis testing.

                                        2

<PAGE>



      In June 1999, the Company announced the signing of a letter of intent with
General Prescription Programs,  Inc., a prescription benefit manager ("GPP") and
others,  to form a new company called  PsiMedica,  to provide  population health
management  and medical  claims  processing  services to third-  party payors of
health related claims and benefits.  The new company,  which will be principally
funded by  Bio-Reference,  is  expected  to obtain a license  to market  medical
management  services to GPP  customers  representing  approximately  one million
lives. The license will also provide the new company with access to GPP's claims
information  and  analytical  software.  The Company  believes  that through the
analytical process of interrelating laboratory,  prescription and medical claims
data, it can provide  critical  strategies  and solutions to promote  population
health management primarily to ERISA funds and other payors.No assurances can be
given that the Company will be able to successfully  market these strategies and
solutions.

      In September  1999,  Bio-Reference  announced  the opening of its Internet
drug screen website,  "DRUGSCREENLAB.COM"  to provide  drug-related  medical and
technical information for both professionals and non-professionals. The site was
established to answer  questions or concerns  about drug testing  procedures and
services  rendered  by  Bio-Reference  as well as about  drug  testing  laws and
requirements.

      In November 1999, the New York State Department of Corrections renewed its
contract  with  Bio-Reference's   wholly-owned   Medilabs  subsidiary  retaining
Medilabs  to  perform  all  laboratory  testing  for  the  Department's  seventy
correctional  institutions in the state  encompassing over 70,000 prisoners from
maximum security prisons to rehabilitation centers. Bio-Reference estimates that
revenues from this contract will aggregate  approximately $6.3 million in fiscal
year 2000, an increase of more than 10% over fiscal year 1999.

      On December  2, 1999,  the Company  acquired  the WEB  Business of Medical
Marketing Group, Inc. ("MMGI") including its Internet website  "DoctorNY.com" as
well as certain website-based  agreements and arrangements with MMGI's physician
clients in the New York  metropolitan  area for an aggregate  140,000  shares of
Bio-Reference's  authorized but unissued  common stock.  MMGI also agreed during
the  period  that  its  Advertising   Consulting   Agreement  with  the  Company
(hereinafter  described) is in effect, to market Internet  -oriented services to
healthcare and healthcare related businesses for linking to and participation in
the WEB  Business  conducted  by the  Company.  The  Company has agreed to pay a
commission  to MMGI equal to 15% of the  recurring  Internet  access and website
fees received by the Company from additional  customers produced by MMGI through
its sales  efforts but solely with  respect to those  customers  produced  after
production of the 1,000th additional customer.

      The "DoctorNY.com"  website, with its associated domain sites and existing
physician websites,  includes website  development  capabilities for subscribing
physicians as well as a search engine allowing consumers to locate physicians by
region, credentials, specialty or other parameters. The Company plans to further
develop   the   physician   services   offered   by  the   system   to   enhance
physician-patient  and  physician-payor  electronic  communications  on a secure
basis (i.e., preserving  confidentiality),  including  communicating  laboratory
results, e-mail prescriptions, refills, payor verification and eligibility, etc.
The offering of physician CME credits  through the system is also  contemplated.
The Company intends to market these services to its existing  physician  network
as well as to other individual physicians and groups of physicians.

      Pursuant to  non-competition  agreements  executed in connection  with the
acquisition,  the Company issued an additional 20,000 shares of  Bio-Reference's
authorized  but unissued  common  stock to MMGI,  an  additional  40,000 of such
shares to MMGI's  principal  stockholder and chief executive  officer,  and paid
$10,000 to a former MMGI executive officer. The Company also executed a one-year
Advertising  Consulting  Agreement  (renewable  by the  Company for a maximum of
three  additional  one- year  terms),  pursuant  to which MMGI  agreed to render
advertising  consulting,  advisory  and public  relations  services  for the WEB
Business  operated by  Bio-Reference,  on a project by project  basis.  For such
services,  MMGI will be paid a minimum  consulting fee of $40,000 in the Initial
Year and of $50,000 in any  subsequent  year,  the minimum  consulting fee to be
credited  against a Consulting Fee calculated  based upon mutually  agreed rates
with  respect  to  each  project  performed  under  the  Advertising  Consulting
Agreement.  As an  additional  inducement  to MMGI to market  Internet  oriented
services to healthcare  and  healthcare  related  businesses  for linkage to and
participation in the WEB Business conducted by the Company,  the Company granted
an  option  to  MMGI  exercisable  to  purchase  a  maximum  100,000  shares  of
Bio-Reference's authorized but unissued common stock at an exercise price

                                        3

<PAGE>



of $3.00  per share  (equal  to the last  reported  per  share  sales  price for
Bio-Reference  common stock on The Nasdaq Stock Market on December 1, 1999,  the
day immediately preceding the acquisition).  The option is only exercisable with
respect  to  those  shares  as to which it  becomes  "vested,"  from the date of
vesting  until  one  year  after  completion  of the  term  of  the  Advertising
Consulting  Agreement.  The option  becomes vested as to each 25,000 shares upon
delivery by MMGI of 500 additional  customers for the WEB Business  conducted by
the Company.

      On December 14,  1999,  the Company  acquired the Health Food  Business of
Right Body Foods, inc. ("RBF"), a manufacturer of starch free, low carbohydrate,
low caloric food products  distributed in Long Island,  New York, through health
professionals,  dieticians,  nutritionists  and physicians.  The acquisition was
effected through a newly formed,  wholly-owned  Company  subsidiary.  The Health
Food Business was acquired for an aggregate  180,000  shares of  Bio-Reference's
authorized but unissued  common stock.  The Company intends to attempt to expand
the market for the Health Food Business  products through its current  physician
accounts utilizing its existing sales force and distribution network.

      The  Company  also  executed  an  employment  agreement  with RBF's  chief
executive  officer,  employing her through October 31, 2004 to perform executive
and  marketing  duties in  connection  with the  establishment,  supervision  of
manufacturing  and marketing of products for the Health Food Business.  Pursuant
to the employment agreement,  the executive will be paid a minimum annual salary
of $150,000 and commissions equal to varying  percentages (from 5% to 1%) of net
cash receipts of the Health Food Business in each fiscal year to the extent such
net cash receipts exceed $1,000,000 in such fiscal year. The commissions  earned
will be credited against a guaranteed  $50,000  commission bonus (effective only
for the first year).  The executive is also being paid a $100,000  signing bonus
in 24 monthly installments. The executive was issued an additional 20,000 shares
of Bio-Reference's  authorized but unissued common stock in consideration of her
executing a non-competition agreement.

      At November  1, 1998,  the  Company  was being  represented  by counsel in
connection  with  various  reviews  being  conducted by the  Company's  Medicare
carrier.  One review  involved  overpayments  that occur in the normal course of
business.   The  Company  believes  the  overpayments   will  be  determined  to
approximate  $150,000,  of which approximately $75,000 has already been remitted
by the  Company to  Medicare.  Counsel  representing  the Company in this matter
advised  at such time that he could not offer any  opinion or  projection  as to
whether  the  anticipated  liability  will be resolved at $150,000 or whether it
will be  increased.  Counsel  further  advised  that  based  upon his  review of
documents, many of the claims that Medicare thought were duplicate payments were
not in fact duplicates,  but rather were properly  billed.  Counsel also advised
that in view of the complexity of this issue, he believed the final  overpayment
would be an amount  negotiated  between the Company and Medicare.  During fiscal
1999, there was no change in the status of this matter. At October 31, 1999, the
Company had  reserved  the sum of  $150,000  on its  October 31, 1999  financial
statements as the estimated liability in connection therewith.

      In  January  2000,  the  Company  commenced  negotiations  with New Jersey
Medicaid regarding a claim (the "Claim") made by the State in December 1999 that
with respect to certain clinical laboratory tests for which  reimbursements were
made by the State to the Company,  although  such tests were  authorized  by the
physician,  the underlying  laboratory test requisitions did not bear the actual
signature of the physician  ordering the test. The Company  believes that it has
been in compliance with all  requirements  regarding bills submitted for payment
by New Jersey Medicaid and requires actual physician  signatures before it bills
New Jersey  Medicaid.  However,  in order to dispose of the issue,  the  Company
entered  into an oral  agreement  with New Jersey  Medicaid  in January  2000 to
settle  the Claim for  approximately  $227,000.  The  Company  has  accrued  the
estimated  settlement of $227,000 on its October 31, 1999 financial  statements.
The  settlement  is subject to the  parties'  execution  of a written  agreement
setting  forth its terms and to the  approval of the Director of the Division of
Medical  Assistance.  Approval of the  settlement  is being  recommended  to the
Director.

      New Jersey  Medicaid  is the only payor  with which the  Company  conducts
business that requires a physician signature on each laboratory requisition.  In
the fiscal year ended  October  31,  1999,  New Jersey  Medicaid  accounted  for
approximately 3% of the Company's total net revenues.






                                        4

<PAGE>



                         CLINICAL LABORATORY OPERATIONS
                         ------------------------------

The Clinical Laboratory Industry
- --------------------------------

      The United States market for clinical  laboratory  testing is estimated to
generate approximately $30 billion in annual revenues.
      -  50% of these revenues are generated by hospital laboratories
      -  50% of these  revenues are generated by  independent  laboratories  and
         physician office laboratories.

History
- -------

      Bio-Reference  was incorporated in December 1981 to provide mobile medical
examination services but discontinued that business in June 1989.  Bio-Reference
commenced clinical  laboratory  operations in 1987 with the belief that a strong
business  opportunity  existed  for  a  medium-sized  clinical  laboratory  that
produced high quality test results in a timely manner to practicing  physicians.
The current competition may be primarily categorized in two groups:
      -  businesses that are national in scope performing millions of tests
         per month but impersonal in nature
      -  smaller  laboratories  that  attempt to compete in terms of quality and
         service but are limited in resources and scope of capabilities.
Consequently,  management  believed  that there  existed a definite  place for a
medium-sized commercial laboratory in the greater New York metropolitan area.

      The  Company  did not  realize  income  from  operations  from the time it
commenced clinical laboratory  operations in 1987 until fiscal 1994. The Company
realized net income in each of the  succeeding  years until fiscal 1999.  During
fiscal 1999, the Company had a loss of approximately $4,900,000 which included a
write-down of  approximately  $2.9 million for an impaired asset of $900,000 and
its  associated   additional  reserve  of  $2,000,000  for  accounts  receivable
attributable  to the Company's end stage renal dialysis  business  acquired from
Smith Kline Beecham.

      In 1988,  the Company  consolidated  and relocated  all of its  laboratory
operations   into  a  35,000  sq.  ft.  space  in  Elmwood  Park,   New  Jersey,
approximately 10 miles from mid-town  Manhattan.  The new location was carefully
chosen to offer easy access to the greater New York metropolitan area. This move
afforded  the Company an  excellent  geographical  location to expand into newer
markets in southern New York State, including  Westchester,  Rockland and Nassau
Counties, southern and western New Jersey and southern Connecticut.

      Bio-Reference proceeded to develop esoteric testing, while maintaining its
routine  tests.  It was found that by emphasizing  the more  difficult  esoteric
tests,  routine tests also increased,  particularly profile testing in chemistry
and  hematology.  The  Company  hopes  to  continue  its  growth  by  aggressive
marketing,  entry into  additional  markets,  primarily  in the greater New York
metropolitan  area through  acquisitions  and the development of specialty niche
markets to  complement  its routine  business.  Over the years,  the Company has
expanded its specialty testing services to include:
      - anatomic pathology (biopsies and pap smears)
      - cellular  immunology  (principally  geared to the AIDS testing market)
      - male infertility
      - tumor markers

Operations
- ----------

      The efficiency of a medical laboratory depends on three items:

      - Quantity of tests
      - Selection of tests performed
      - Ability to automate the process





                                        5

<PAGE>



        It is axiomatic  that the initial  fixed costs of testing a small number
of patients are high. Such costs include:
      -  cost of maintaining highly sophisticated equipment
      -  cost of a full support facility
         -  marketing
         -  logistical
         -  billing
         -  other administrative costs
As the patient  volume  increases,  automated  tests become  progressively  less
expensive as the fixed costs are already in place,  making the  laboratory  more
cost efficient.

      Most  medical  laboratory  tests  can  be  divided  into  three  principal
      categories:
      - those that are highly automated and computer driven,
      - those that are semi-automated  requiring the use of sophisticated
        equipment,
      - those that are subjective and basically manually determined.
The Company considers itself a highly automated and computer driven laboratory.

      The Company's  couriers pick up patient specimens from physician  offices,
nursing homes and hospitals in the  metropolitan  New York area and test results
are generally  delivered  back to the physician  within 24 hours.  Larger volume
clients receive test results by way of printers placed in their offices, thereby
accelerating test reporting.  Bio-Reference furnishes its physician clients with
periodic newsletters detailing:
      - advances in laboratory  medicine
      - new tests
      - clinical  commentaries
      - aboratory interpretation of test results.

In addition,  the Company  provides an annual Test  Compendium  to all physician
clients listing:

      - all tests offered
      - normal ranges
      - correct collection of samples
      - patient preparation
      - up to date billing information

      The Company  utilizes the services of eighteen  full-time  Client  Service
Coordinators,   all  of  whom  are  fully  trained  in  medical  and  laboratory
terminology.  This staff is used as an interface with  physicians and nurses and
augments  the client  support  provided by the  Company's  sales  staff.  Highly
abnormal  and  life  threatening  results  are  immediately  telephoned  to  the
physician in order to provide speedy medical resolution of any patient problem.

Sales and Marketing
- -------------------

      The Company  presently  employs 47 full and part-time  sales and marketing
personnel.  The sales and marketing  department works closely with the Technical
Director to:
      -  plan new tests
      -  pricing
      -  general client support.
All sales and marketing  personnel  operate in a dual capacity;  both in selling
and as client support  representatives.  This ensures that all  salespersons are
intimately  involved with the client, not only in selling,  but in servicing the
account  that  they  sell.  Bio-Reference  believes  that  this is unique in the
industry and is extremely helpful in client  retention,  providing a strong link
between the physician and the Company's staff.

Quality Assurance
- -----------------

      Medical testing is essentially one of communication and data transfer.  In
order to provide  accurate  and  precise  information  to the  physician,  it is
essential to maintain a well structured and vigorous quality assurance  program.
Bio-Reference  holds the required Federal and state licenses necessary to permit
its  operation  of a  clinical  laboratory  at both its New  Jersey and New York
facilities and to permit the servicing of its clients in  Connecticut,  Florida,
Louisiana, Maryland, New Jersey, New York,

                                        6

<PAGE>



Pennsylvania and Virginia. To fully maintain these licenses, the laboratory must
submit to vigorous sets of proficiency tests, or surveys, in all test procedures
which are performed.  Such proficiency tests or surveys may be performed as many
as four to five  times a year,  depending  upon the  procedure,  and  results in
hundreds of  proficiency  tests  throughout  the year. In addition,  the Company
performs  thousands of quality control and quality assurance tests per year. The
Company is also subjected to unannounced  inspections by inspectors from some of
the  jurisdictions  noted  above who review  past  records,  operating  manuals,
quality assurance records and safety regulations.

      In October 1998,  the Company was notified that it had been  re-accredited
by the College of American  Pathologists  "CAP" in its Elmwood Park,  New Jersey
and Park  Avenue,  New York  facilities.  In  September  1998,  the  Company was
notified  that  it had  been  re-accredited  in its  Valley  Cottage,  New  York
facility.  This  accreditation by CAP, a peer review  organization,  involves an
intensive  review by  numerous  experts  in their  specific  fields,  who review
technical,  quality assurance,  health and safety and computer  documentation in
order to bestow  accreditation,  which is one of the most prestigious  approvals
available to clinical laboratories.

      The Company's Quality Assurance  Committee,  headed by a Quality Assurance
Coordinator  and composed of supervisors  from all  departments,  meets daily to
assess and evaluate the laboratory's quality.  Based on the information received
from the committee,  recommendations  are made to correct  conditions which have
led to errors.  Management,  department supervisors and members of the assurance
committee continually monitor the laboratory's  quality.  Depending on the test,
two or three sets of Quality Control  materials are run in each analytical assay
to assure precision and accuracy.  Patient  population  statistics are evaluated
each day. Highly abnormal samples are repeated to assure their accuracy.

      It is the Company's  position that all of these  procedures are necessary,
not only in  assuring a quality  product,  but also in  maintaining  Federal and
state  licensing.  The Company  believes  these high standards of quality are an
important  factor in what  management  regards  as an  excellent  rate of client
retention.

Revenue Recognition and Business Strategy
- -----------------------------------------

      Although the laboratory's clients are primarily physicians,  it is usually
the  individual  patient,   his  or  her  commercial  insurance  carrier,  or  a
governmental  agency  such as  Medicare  or  Medicaid  that pays the  laboratory
charges.  These third parties pay health care  providers  according to allowable
costs  or  a  predetermined  contractual  rate  rather  than  according  to  the
provider's  established  rates; the difference  between what is paid and what is
billed is the  contractual  allowance.  Therefore,  the  Company has adopted the
practice  of  reducing  its  revenues  by  these   allowances   or   contractual
adjustments.

      Over the past years  there has been an  increase in the number of patients
that are covered by managed care health plans.  These plans will often negotiate
with a limited  number of clinical  laboratories  at discounted  rates.  Some of
these managed care health plans will contract with only a single  laboratory and
pay for  services  on a  capitation  basis  (meaning  one  price  per  enrollee,
regardless of how much laboratory work is performed). The effect of managed care
health plans to the laboratory industry equates to lower reimbursement rates for
laboratory  services.  If the  laboratory  is not a provider  of services to the
managed care health plan,  it will not be  reimbursed  for providing the service
and overall  patient volume may be reduced.  Therefore,  this change has reduced
the  potential  market  for a  clinical  laboratory's  services  if it is  not a
provider to a particular managed care health plan.

      In  addition,  Medicare  as well as an  increasing  number  of  commercial
programs  are  requiring  physicians  to  document  the medical  necessity  when
ordering specific laboratory tests. Since the laboratory has a responsibility to
test a specimen when it first arrives in the  laboratory,  it may not be able to
wait until all  applicable  information  is provided and there is a  possibility
that a test can be performed and results  provided  before  appropriate  medical
necessity  is  documented.  In  these  cases,  the  laboratory  may not  receive
reimbursement  for the  tests.(See  "Developments  Since the Beginning of Fiscal
1999" as to the status of a review  concerning  overpayments  being conducted by
the Company's  Medicare  carrier) and a recent settlement of a claim against the
Company asserted by New Jersey Medicaid.





                                        7

<PAGE>



       The following table reflects the Company's  breakdown of revenue by payor
for the 12 months ended October 31, 1997, 1998 and 1999.

                                            Years Ended October 31,
                                              1997  1998  1999
                                              ----  ----  ----

            Direct Patient Billing...........   17%   16%  14%
            Commercial Insurance.............   31%   30%  27%
            Professional Billing.............   23%   28%  34%
            Medicare.........................   25%   22%  22%
            Medicaid.........................    4%    4%   3%
                                             ------   --- ----
                                               100%  100% 100%
Competition
- -----------

      Bio-Reference's  competition  derives  primarily  from other  laboratories
located in the New York  metropolitan  area. On a national basis,  approximately
30% of this market is made up of the two largest national laboratories:
      -  Quest Clinical Laboratory, formerly a Division of Corning, Inc.
      -  Laboratory Corporation of America, Inc.

      Although   the  Company  is   significantly   smaller  than  the  national
laboratories  and has modest  financial  resources,  management  believes it can
compete successfully because it has;
      -  fewer  layers  of  staff
      -  a more  responsive  business  atmosphere
      -  customized service.
The Company  believes  its response to medical  consultation  is faster and more
personalized than in the national  laboratories.  Client service staff only deal
with  basic  technical  questions  and those  that have  medical  or  scientific
significance are referred directly to other senior scientists and staff.

Government Regulation
- ---------------------

      Laboratory operations require licensure in each jurisdiction in which they
operate.  Bio-Reference  holds the required Federal and state licenses necessary
to permit its operation of a clinical  laboratory at both its New Jersey and New
York facilities and to permit its servicing of its clients in those states where
it  presently  operates.  Laboratory  technicians  and  technologists  must also
qualify under state  regulations in order to be employed by the laboratory.  All
of these  licensing  and  certification  programs set standards in areas such as
quality  control,  record keeping and personnel  qualifications,  including,  in
varying measures from state to state,  educational  experience and licensure for
various  levels of  personnel  responsible  for testing.  Compliance  with these
standards is by periodic inspections by the appropriate Federal,  state or local
agency. In addition,  licensing and  certification  entail  proficiency  testing
which involves actual testing of specimens that have been specifically  prepared
by  the  regulatory   authority  or  designated  agencies  for  testing  by  the
laboratory. There can be no assurance the laboratory will maintain all necessary
licenses  and in the event the  laboratory  loses its  license  in a  particular
jurisdiction,  it will be required to cease all activities in such jurisdiction.
There also cannot be any assurance the Company will obtain the licenses required
in a proposed jurisdiction of operation.

      The Company is also subject to Federal and state regulations governing the
transportation  and disposal of medical waste including  bodily fluids.  Federal
regulations  require  licensure of interstate  transporters of medical waste. In
New Jersey, the Company is subject to the Comprehensive Medical Waste Management
Act,  "CMWMA,"  which requires the Company to register as a generator of special
medical waste.  CMWMA mandates the  sterilization  of certain  medical waste and
provides a tracking  system to insure disposal in an approved  facility.  All of
the Company's medical waste is disposed of by a licensed  interstate hauler. The
hauler provides a manifest of the disposition of the waste products as well as a
certificate of incineration which is retained by the Company.  These records are
audited by the State of New Jersey on a yearly basis.

      Containment of health-care  costs,  including  reimbursement  for clinical
laboratory services, has been a focus of ongoing governmental activity.  Omnibus
budget  reconciliation  legislation,  designed to "reconcile" existing laws with
reductions and reimbursement required by enactment of a Congressional budget can
adversely affect clinical  laboratories by reducing  Medicare  reimbursement for
laboratory

                                        8

<PAGE>



services.  Although in the past,  legislation has been enacted which reduced the
permitted  Medicare   reimbursement  for  clinical   laboratory   services  from
previously  authorized levels,  none of the reductions enacted to date has had a
material  adverse  effect on the Company.  For many of the tests  performed  for
Medicare beneficiaries or Medicaid recipients, laboratories are required to bill
Medicare or Medicaid directly,  and to accept Medicare or Medicaid reimbursement
as payment in full.

      The Clinton  Administration,  Congress and various  Federal  agencies have
examined  the rapid  growth of  Federal  expenditures  for  clinical  laboratory
services, and the use by the major clinical laboratories (including the Company)
of  dual  fee  schedules  ("client"  fees  charged  to  physicians,   hospitals,
institutions  and  companies  with whom a  laboratory  deals on a bulk basis and
which involve relatively low administrative costs, and "patient" fees charged to
individual patients and third party payors,  including  Medicare,  who generally
require  separate  bills or claims for each patient  encounter and which involve
relatively high administrative costs). The permitted Medicare reimbursement rate
for clinical laboratory services has been reduced by the Federal government in a
number of instances  over the past several years to a present level equal to 74%
of the  national  median  of  laboratory  charges.  A number  of  proposals  for
legislation  or regulation are under  discussion  which could have the effect of
substantially reducing Medicare  reimbursements to clinical laboratories through
reduction  of the  present  allowable  percentage  or through  other  means.  In
addition,  the structure  and nature of Medicare  reimbursement  for  laboratory
services  is also under  discussion  and  management  is unable to  predict  the
outcome of these  discussions  or its effect on the Company.  Depending upon the
nature of congressional and/or regulatory action, if any, which is taken and the
content of legislation, if any, which is adopted, the Company could experience a
significant decrease in revenues from Medicare and Medicaid,  which could have a
material  adverse  effect on the  Company.  The  Company  is unable to  predict,
however, the extent to which any such actions will be taken.

      Federal  and state  health  care and  related  regulations  are subject to
constant  change.  The Company  cannot now predict  what  changes may be enacted
which may  affect its  business  or the  manner in which its  business  would be
affected by such changes.  Two  legislative  changes have occurred which portend
significant  changes in the  clinical  laboratory  market.  Two  Omnibus  Budget
Reconciliation  Acts have severely  restricted  physician  referrals of Medicare
covered  services to clinical  laboratories in which the referring  physician or
his  immediate  family has a financial  relationship.  The  Clinical  Laboratory
Improvement  Amendments of 1988,  "CLIA-88," acted to strengthen Federal control
of medical  laboratories by regulating  stricter  quality  assurance  practices,
licensing requirements and staff qualifications.

      CLIA-88   extended   Federal   licensing   requirements  to  all  clinical
laboratories (regardless of the location, size or type of laboratory), including
those  operated by physicians in their  offices,  based on the complexity of the
tests they perform.  The legislation also substantially  increased regulation of
cytology screening,  most notably by requiring the Secretary of Health and Human
Services,  ("HHS,") to  implement  regulations  placing a limit on the number of
slides that a cytotechnologist may review in a twenty-four hour period.  CLIA-88
also established a more stringent  proficiency  testing program for laboratories
and  increased  the  range and  severity  of  sanctions  for  violating  Federal
licensing  requirements.  A number of these  provisions,  including  those  that
imposed stricter cytology standards and increased proficiency testing, have been
implemented by regulations  applicable only to laboratories  subject to Medicare
certification  adopted under the Clinical  Laboratory  Improvement  Act of 1967,
"CLIA-67."  On  February  28,  1992,  HHS  published  three sets of  regulations
implementing  CLIA-88,   including  quality  standard  regulations  establishing
Federal quality standard for all clinical laboratories; application and user fee
regulations  applicable to most  laboratories  in the United States which became
effective on March 30 1993; and enforcement procedure regulations  applicable to
laboratories  that are  found not to meet  CLIA- 88  requirements.  The  quality
standard  regulations  establish varying levels of regulatory scrutiny depending
upon the complexity of testing performed.  Under these regulations, a laboratory
that performs only one or more of eight routine  "waived"  tests may apply for a
waiver from most  requirements of CLIA-88.  The Company believes that most tests
performed by physician office laboratories will fall into either the "waived" or
the "moderately  complex"  category.  The latter  category  applies to simple or
automated tests and generally permits existing personnel in physicians'  offices
to continue to perform testing under the  implementation  of systems that insure
the  integrity  and  accurate  reporting  of results,  establishment  of quality
control  systems,   proficiency  testing  by  approved  agencies,  and  biannual
inspection.  The quality standard and enforcement  procedure  regulations became
effective on September 1, 1992, although certain personnel,  quality control and
proficiency testing requirements will

                                        9

<PAGE>



be phased-in over a number of years. The laboratory has completed its first CLIA
inspection  under CLIA-88  guidelines and received its certificate of compliance
effective February 7, 1996.

      In October 1998,  the Company was notified that it had been  re-accredited
by the College of American  Pathologists  "CAP" in its Elmwood Park,  New Jersey
and Park  Avenue,  New York  facilities.  In  September  1998,  the  Company was
notified  that  it had  been  re-accredited  in its  Valley  Cottage,  New  York
facility.  This  accreditation by CAP, a peer review  organization,  involves an
intensive  review by  numerous  experts  in their  specific  field,  who  review
technical,  quality assurance,  health and safety and computer  documentation in
order to bestow  accreditation,  which is one of the most prestigious  approvals
available to clinical laboratories.

      The Office of Inspector  General has published a Model Compliance  Program
for  the  clinical  laboratory  industry.   This  is  a  voluntary  program  for
laboratories to demonstrate to the Federal  government that they are responsible
providers.  Bio-Reference  Laboratories has written and implemented a compliance
program adhering to the standards set forth in the Model Compliance Program.

Insurance
- ---------

      The Company maintains  professional  liability insurance of $1,000,000 per
occurrence,  $3,000,000 in the  aggregate.  In addition,  the Company  maintains
excess  commercial  insurance of $2,000,000 per occurrence.  A determination  of
Company  liability for uninsured or underinsured  acts or omissions would have a
material adverse effect on the Company's operations.

Employees
- ---------

      At December  31, 1999,  the Company had 378  full-time  employees  and 368
part-time employees. This includes:
      -  three executive officers
      -  Vice President of Technical Operations
      -  Marketing Vice-President,
      -  74 full-time and 41 part-time technicians, and/or technologists
         (including physicians, pathologists and Ph.D.'s)
      - 260 full and part-time  semi-technical employees
      - 46 full and part-time marketing  representatives
      - 194 full and part-time  clerical  employees
      - 107 full and part-time drivers.
None of the Company's  employees are  represented by a labor union.  The Company
regards relations with its employees as satisfactory.

Item 2 - Properties
- -------------------

      The Company's  executive offices and New Jersey processing facility occupy
approximately  56,000  square  feet  of  leased  space  in two  one-story  brick
facilities at 481-487 Edward H. Ross Drive,  Elmwood Park, New Jersey. The lease
for these  facilities,  which expires in February  2004,  provides for a monthly
rental  of  $31,391.  Bio-Reference's  New  York  processing  facility  occupies
approximately  11,000 square feet of leased space in a two-story  brick facility
at 140 Route 303, Valley Cottage,  New York. The lease for this facility,  which
expires in April 2002,  provides for a monthly rental of $12,177.  The Company's
testing  equipment  maintained at both of its processing  facilities are in good
condition and in working order.  Management  believes that these facilities,  as
presently   equipped,   have  the  capacity  to  generate  up  to  approximately
$75,000,000 in annual  revenues based on the type of testing now being performed
by the  Company.  The Company  maintains  fire,  theft and  liability  insurance
coverage for this facility in what it believes are adequate amounts. The Company
also leases 55 additional relatively small draw stations throughout the New York
metropolitan  area to collect  specimens  from  physician-referred  patients for
testing at both of its processing facilities.

Item 3 - Legal Proceedings
- --------------------------

      In July 1996, the Company  purchased  certain assets and rights  including
the Customer List related to the Renal Dialysis  Testing  Business  conducted by
SmithKline  Beecham  Clinical  Laboratories,   Inc.  ("SBCL"),  from  SBCL,  for
$1,800,000 including a $1,200,000 down payment pursuant to an Asset

                                       10

<PAGE>



Sale/Purchase  Agreement (the "Asset Agreement").  In the Asset Agreement,  SBCL
represented and warranted that its Renal Dialysis Testing Business was servicing
at least 60 active  accounts,  was  conducting  testing  for not less than 4,600
active  dialysis  patients and was generating at least $3,600,00 in net revenues
on an annual basis. The parties also executed a  Non-Competition  Agreement (the
"Non- Competition  Agreement") pursuant to which SBCL agreed to cease performing
all renal dialysis clinical  laboratory testing services for a three year period
(after conclusion of a limited Transition Period).

      After completion of the acquisition,  the Company's management  determined
that SBCL's representations and warranties concerning the Renal Dialysis Testing
Business  were  materially  false  and  that  the  Company  might  only  realize
approximately  $1,000,000  in annual net revenues  from the  acquired  business.
Management also determined that SBCL had  fraudulently  concealed that its Renal
Dialysis Testing Business had suffered certain material adverse changes and that
SBCL had breached the Non- Competition  Agreement by continuing to perform renal
dialysis testing on the transferred accounts after the Transition Period despite
its  assurances  that it had ceased all such testing.  Based upon SBCL's alleged
breaches of the Asset Agreement and the Non-Competition  Agreement,  the Company
did not pay any portion of the $600,000 balance of the purchase price (which was
due in 24 consecutive  monthly  installments  of $25,000  commencing  January 1,
1997).

      As a result of the foregoing,  the Company filed a lawsuit against SBCL in
December  1996. The lawsuit,  filed in the United States  District Court for the
District of New Jersey, alleged that SBCL materially and repeatedly breached its
obligations and its  representations  and warranties made in the Asset Agreement
and  the   Non-Competition   Agreement  and  claimed   unspecified   amounts  of
compensatory  and  punitive  damages  and  related  costs.  In  response  to the
Company's lawsuit,  SBCL asserted  counterclaims for the $600,000 unpaid portion
of the purchase price.

      During fiscal 1998,  agreement was reached between the Company and SBCL to
settle  and   compromise   all  aspects  of  the  lawsuit   including  the  SBCL
counterclaims.  Pursuant to the  agreement,  the Company  released SBCL from any
claims  pursuant to the Asset  Agreement and the  Non-Competition  Agreement and
SBCL released the Company from any claims pursuant to such agreements  including
the Company's  obligation to pay the $600,000 balance of the purchase price. The
settlement  was subject to the consent of the Company's  principal  lending bank
which consent was received in January 1999.

Item 4 - Submission of Matters to a Vote of Security Holders
- ------------------------------------------------------------

      The Company's Annual Meeting of Stockholders was held on October 21, 1999.
At the meeting, the following two individuals were elected by the following vote
to serve as Class II  directors,  each for a term of three  years  and until his
successor is duly elected and qualified.

                                               For     Withheld
                                               ---     --------

      Sam Singer                           6,362,497    152,972

      Frank DeVito                         6,362,497    152,972

The other directors of the Company whose term continued are as follows:

      Marc D. Grodman                            Class I director

      Howard Dubinett                            Class I director

      John Roglieri                              Class III director

      Gary Lederman                              Class III director



                                       11

<PAGE>




                                     PART II

                            PRICE RANGE OF SECURITIES
                            -------------------------

Item 5. -  Market for Common Stock and Related Shareholder Matters
- ---------  -------------------------------------------------------

      The  Company's  Common  Stock was traded on the  National  Association  of
Securities Dealers Automated Quotation  ("NASDAQ") Small Cap System through July
13, 1992 after which it was delisted from trading on NASDAQ due to the Company's
failure to maintain shareholders' equity of at least $1,000,000. Commencing July
14, 1992, the Common Stock was quoted in the over-the-counter market on the NASD
OTC Bulletin Board.  As a result of the  improvement in the Company's  financial
condition  based upon its November  1993 public  offering,  the Common Stock was
readmitted for trading on the NASDAQ Small Cap System under the symbol "BRLI" on
November 24, 1993.

      The  following  table  sets forth the range of high and low bid prices for
the Common Stock for the periods indicated, as derived from reports furnished by
NASDAQ.  Such  quotations  represent  prices  between  dealers,  do not  include
mark-ups,  mark-downs or commissions  and may not necessarily  represent  actual
transactions.

         Fiscal Year                                  Bid Prices
         -----------                                  ----------

                                                  High          Low
                                                  ----          ---

         1998
            First Quarter                        $1.65625    $1.25
            Second Quarter                        1.75        1.25
            Third Quarter                         2.00        1.15625
            Fourth Quarter                        1.25         .875
         1999
            First Quarter                        $1.875     $  .96875
            Second Quarter                       $1.5625       .75
            Third Quarter                        $1.03125      .4375
            Fourth Quarter                       $1.0625       .78125

      At  December  31, 1999 the  closing  sales  price for the Common  Stock on
NASDAQ was $3.75 per share.

      At December 31, 1999 the number of record  holders of the Common Stock was
630. Such number of record owners was determined from the Company's  shareholder
records and does not include  beneficial owners whose shares are held in nominee
accounts with brokers, dealers, banks and clearing agencies.

Dividends

      The Company  has not paid any  dividends  upon its Common  Stock since its
inception and, does not  contemplate  or anticipate  paying any dividends in the
foreseeable  future.  Furthermore,  the Company's  loan  agreement with PNC Bank
prohibits  the Company from paying  dividends or making any  distributions  with
respect  to any shares of its stock  without  the prior  written  consent of the
Bank.


                                       12

<PAGE>




Item 6.  Selected Financial Data
                                        [In thousands, except per share data]
                                               Y e a r s     e n d e d
                                    --------------------------------------------
                                                O c t o b e r   3 1,
                                    --------------------------------------------
                                     1 9 9 9  1 9 9 8  1 9 9 7  1 9 9 6  1 9 9 5
                                     -------  -------  -------  -------  -------
Operating Data:
  Net Revenues                       $ 53,856 $ 46,554 $38,660 $ 35,126 $ 31,521
  Cost of Services                   $ 30,850 $ 25,058 $19,339 $ 18,136 $ 15,036
  Gross Profit                       $ 23,006 $ 21,496 $19,321 $ 16,989 $ 16,485
  General and Administrative Expenses$ 26,432 $ 20,231 $17,436 $ 15,793 $ 14,702
  Income [Loss] from Operations      $ (3,426)$  1,065 $ 1,885 $  1,196 $  1,783
  Non-Recurring Gain on Sale of
    Intangible Assets                $     -- $    334 $ 2,026 $     -- $     --
  Other Expenses - Net               $  1,185 $    841 $   850 $    552 $    332
  Provision for Income Tax Expense
     [Benefit]                       $    367 $    (38)$  (139)$     52 $     49
  Net income [Loss]                  $ (4,978)$    597 $ 3,200 $    592 $  1,402
  Net [Loss] Income Per Common Share $   (.68)$    .08 $   .48 $    .10 $    .23
  Cash Dividends Per Common Share    $     -- $     -- $    -- $     -- $     --

Balance Sheet Data:
  Total Assets                       $ 32,318 $ 40,778 $29,095 $ 28,231 $ 24,201
  Total Long-Term Liabilities        $  2,681 $  3,708 $   921 $  1,533 $    843
  Total Liabilities                  $ 20,948 $ 24,555 $13,570 $ 16,128 $ 12,945
  Working Capital                    $  3,452 $  8,364 $ 9,415 $  4,072 $  4,552
  Stockholders' Equity [Deficit]     $ 11,369 $ 16,223 $15,525 $ 12,103 $ 11,256

      A number of  proposals  for  legislation  continue to be under  discussion
which  could  substantially  reduce  Medicare  and  Medicaid  reimbursements  to
clinical  laboratories.  Depending upon the nature of regulatory  action and the
content of legislation,  the Company could experience a significant  decrease in
revenues from Medicare and Medicaid, which could have material adverse effect on
the Company. The Company is unable to predict, however, the extent to which such
actions will be taken.

Item 7.  Management's Discussion and Analysis of Financial Condition
         and Results of Operations
         -----------------------------------------------------------------------

Note Regarding Forward-Looking Statements
- -----------------------------------------

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

OVERVIEW
- --------

Bio-Reference has expanded its laboratory testing  capabilities and its customer
base through  internal  growth as well as through the  completion of a series of
acquisitions of the businesses of other testing laboratories.

In April  1998,  the Company  acquired  the assets and  certain  liabilities  of
Medilabs, Inc. ("MLI") for a purchase price of $4,000,000 cash plus a promissory
note of $1,500,000,  payable without interest, in three semi-annual installments
commencing  April  of 1999.  Also in  April,  the  Company  entered  into a note
agreement  to borrow the  $4,000,000  to fund this  acquisition.  The note is in
accordance  with the Company's  revolving  loan  agreement with the same lending
bank. The operations of MLI are included in the Company's operations  commencing
April 9, 1998. MLI incurred a net loss of  approximately  $120,000 for the seven
month period ended October 31, 1998 and had net income of approximately $880,000
for the twelve month period ended October 31, 1999.


                                       13

<PAGE>



In  December  of 1999,  the  Company  entered  into  agreements  to acquire  the
businesses of two companies.  One company is involved in website designs and the
other company is involved in the manufacturing of health care foods.

Results of Operations

Net Income
- ----------

The  Company's  net income  (loss) for the years ended October 31, 1999 and 1998
was $(4,978,448) and $596,583, respectively. The main reasons for the $5,575,031
decrease  in net  income  is the  write-down  of  approximately  $2,900,000  for
impaired  assets  including the  additional  allowance  for accounts  receivable
relating  to the  Company's  end stage renal  dialysis  business  acquired  from
SmithKline  Beecham of  approximately  $2,000,000 and an increase in general and
administrative  expenses  of  approximately  $2,000,000  in  fiscal  1999.  . In
addition,  net revenue per patient  decreased 8% during the current twelve month
period  ended  October 31,  1999,  as compared to the twelve  month period ended
October 31, 1998.  Gross profit margins  decreased from 46% for the twelve month
period ended  October 31, 1998 to 43% for the twelve month period ended  October
31,  1999.  Based upon  anticipated  increases  in patient  volume,  anticipated
increased  testing  to  be  performed,   reimbursement  rate  improvements,  and
anticipated  decreases in operating  costs, the bulk of the effects of which are
expected to be realized in the second half of fiscal 2000, the Company  projects
net income for fiscal 2000.

Net Revenues
- ------------

Net revenues for the year ended October 31, 1999 were $53,856,414 as compared to
$46,553,730  for the year ended October 31, 1998; this represents a 16% increase
in net revenues. MLI had net revenues of $13,706,743 or 25% of the Company's net
revenues for the fiscal year. The Company acquired MLI in April of 1998, for the
seven month period ended October 31, 1998, MLI had net revenues of $7,773,570 or
17% of the  Company's  net revenue for the twelve month period ended October 31,
1998.

The number of patients  serviced  during the fiscal year ended  October 31, 1999
was 1,235,514  which was 25% greater when compared to the prior fiscal year. MLI
accounted for 35% of the patient count for the year ended October 31, 1999.  Net
revenue per patient for the year ended  October 31, 1998 was $47.29  compared to
net  revenue  per  patient  for the year ended  October  31,  1999 of $43.59;  a
reduction of $3.70 or 8%. This decrease is due to the inclusion of a full twelve
months of MLI's revenues with its associated lower revenue per patient in fiscal
year 1999.  MLI's net revenue per patient was $31.71 for the twelve month period
ended  October 31, 1999  compared to net revenue per patient of $33.04 in fiscal
year 1998.  The Company  expects an increase in net revenues in fiscal year 2000
due to a number of  factors:  internal  growth,  an  estimated  increase  in the
contract  with  the  New  York  State   Department  of   Corrections,   Medicare
reimbursement  for  tests  previously  not  covered,  an  increase  in  Medicare
reimbursement for other selected tests, as well as new marketing  initiatives in
newer testing  areas,  such as drugs of abuse  testing,  and  complimentary  and
alternative medicine. In addition, the Company has identified three new business
initiatives (See Below), all of which seek to leverage off existing capabilities
the Company possesses.

The Company anticipates  increasing its revenues in its next fiscal year through
internal  growth and  development  of new  marketing  initiatives  in laboratory
testing services outside the traditional physician market. In November 1999, the
contract  to provide  laboratory  testing by the New York  State  Department  of
Corrections  for inmates in its facilities was renewed.  This contract is valued
at  approximately  $6,300,000  for fiscal year 2000,  an  estimated  increase of
approximately  10% from fiscal  year 1999.  The Company is seeking to market its
services to other correctional institutions.

In June 1999,  the  Company  announced  the  signing of a letter of intent  with
General Prescription Programs,  Inc., a prescription benefit manager ("GPP") and
others, to form a new company,  called PSIMedica,  which will provide population
health management and medical claims processing  services to third-party  payors
of health related claims and benefits.  The new company,  principally  funded by
BRLI, is expected to obtain a license to market medical  management  services to
GPP customers  representing  approximately  one million lives.  The license will
also  provide  the new  company  with  access to GPP's  claims  information  and
analytical  software.  The Company believes,  through the analytical  process of
interrelating  laboratory,  prescription and medical claims data, it can provide
critical  strategies  and  solutions  to promote  population  health  management
primarily to ERISA funds and other payors. No

                                       14

<PAGE>



assurances  can be given that the Company  will be able to  successfully  market
these strategies and solutions.

In 1999, the Company licensed software to allow for the grouping of the analysis
of  medical  claims  data  and has  proceeded  to  develop  its own  proprietary
algorithms and enhancements to the licensed software so as to include laboratory
and prescription data. The Company is currently negotiating with two ERISA funds
which  total  over  60,000  lives as beta  sites  for its  analytical  tools and
programs.  The Company  expects to seek customers for its services by mid fiscal
year 2000.

In  December  1999,  the  Company  announced  the  acquisition  of  DoctorNY.com
(www.doctorny.com),  a health portal which, with its associated domain sites and
existing  physician  websites,  includes  website  development  capabilities for
health care providers,  together with a search engine which allows  consumers to
locate physicians by region,  credentials,  specialty or other  parameters.  The
Company  announced the consumer view represented by DoctorNY.com was part of its
entry into the e-health  marketplace.  The Company plans to further  develop the
physician  services  offered  by the system to enhance  physician-  patient  and
physician-payor  electronic  communications on a secure basis (i.e.,  preserving
confidentiality),    including   communicating    laboratory   results,   e-mail
prescriptions, refills, payor verification and eligibility, etc. The offering of
physician  CME  credits  through  the system is also  contemplated.  The Company
intends to market these services to its existing physician network as well as to
other individual physicians and groups of physicians.

In December  1999, the Company  acquired Right Body Foods,  Inc., a manufacturer
and distributor of freshly prepared, starch free, low-calorie, low carbohydrate,
food  products,  located in Syosset,  New York.  Its  products  are sold through
health  professionals,  dieticians,  nutritionists  and physicians.  The Company
expects  to use its  marketing  staff and  physician  network  to  increase  the
distribution of these products.

COST OF SERVICES:
- -----------------

Cost of sales increased from  $25,058,008 for the year ended October 31, 1998 to
$30,850,357  for the year ended  October 31, 1999,  an increase of $5,792,329 or
19%. This increase is primarily the result of the MLI acquisition.  MLI's direct
operating  costs were  $9,347,850  for the twelve month period ended October 31,
1999,  as compared to  $5,639,627  for the seven month period ended  October 31,
1998,  an  increase  of  $3,708,223.  The optimum  consolidation  of  laboratory
operations has not been completed and will marginally  impact the Company's cost
structure  until,  at least,  the second  quarter  of fiscal  year 2000 when the
automated  laboratory  upgrade and expansion is expected to be completed.  While
the automated  laboratory  will have a marginal  impact on cost  structure,  the
reduction of the Company's  dependence on reference  laboratories is expected to
have a more favorable impact during the second half of fiscal 2000.

GROSS PROFITS:
- -------------

Gross  profit on net  revenues  increased  from  $21,495,722  for the year ended
October 31, 1998 to $23,006,077 for the year ended October 31, 1999; an increase
of $1,510,355 primarily  attributable to the increase in revenues.  Gross profit
margins  decreased  from 46% for the year ended  October 31, 1998 to 43% for the
year ended October 31, 1999. Management believes that the Company's gross profit
margin will  increase in fiscal 2000,  due to increased  revenues  from internal
growth,  Medicare  reimbursement for tests not previously covered,  increases in
reimbursement  rates from  Medicare  on certain  tests,  the  completion  of the
automated chemistry  laboratory and decrease in direct operating  expenses.  The
decrease in gross profit margins in fiscal 1999 is primarily attributable to the
lower net revenues per patient, the increase in direct costs associated with MLI
and the  duplication of direct costs that had not been  eliminated as of October
31, 1999 by an optimum consolidation of laboratory  operations.  The Company has
invested a large  amount of time and money  during  fiscal 1999 to increase  its
processing capacity.  Management believes,  that its capacity once the automated
chemistry laboratory is completed, for approximately $250,000, will be more than
adequate to handle the projected increase in patient volume.

- ------------------------------------------------------------------------------

Note Regarding Forward-Looking Statements
- -----------------------------------------

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

                                       15

<PAGE>





GENERAL AND ADMINISTRATIVE EXPENSES:
- -----------------------------------

General and  administrative  expenses  for the year ended  October 31, 1999 were
$26,431,909 as compared to  $20,430,757  for the year ended October 31, 1998, an
increase of approximately  $6,000,000 or 29%. Approximately 48% of this increase
is the  impairment  charge  of  approximately  $2,900,000  associated  with  the
Company's end stage renal dialysis business acquired from SmithKline Beecham. In
addition, occupancy expenses,  telephone, data processing and marketing expenses
increased  approximately  $1,900,000  over the prior  twelve month  period.  The
Company  recorded  a $227,000  expense  associated  with a New  Jersey  Medicaid
overpayment claim.  Management believes that general and administrative expenses
in 2000 will increase but not at a higher percentage than the projected increase
in revenues.

INTEREST EXPENSE:
- ----------------

Interest  expense  increased from $1,280,737 for the year ended October 31, 1998
to $1,465,765 for the year ended October 31, 1999,  resulting from the Company's
continuing use of its revolving line of credit with PNC Bank.

Fiscal Year 1998 Compared to Fiscal Year 1997

Net Income
- ----------

The  Company's  net income for the years  ended  October  31,  1998 and 1997 was
$596,583  and  $3,199,915,  respectively.  The main  reasons for the  $2,600,000
decrease in net income is the reduction in  nonrecurring  gain of  approximately
$1,700,000.  The  nonrecurring  gain  represents the gain in the sale of certain
assets  of  the  Company's  GenCare  Division.  The  reduction  in  income  from
operations  resulted from a reduced gross profit  percentage of approximately 4%
and an increase in general and administrative expenses.

Net Revenues
- ------------

On September 30, 1997,  the Company  completed the sale of certain assets of its
GenCare  Division  ("GenCare")  to an unrelated  third party.  GenCare  provided
largely cancer  diagnostic  testing  services with  relatively high revenues per
patient.  The 1997  financial  statements  included  eleven  months of  revenues
attributable  to the  GenCare  division  or  $2,116,523.  There were no revenues
realized by the GenCare Division in 1998.

Net revenues for the year ended October 31, 1998 were $46,553,730 as compared to
$38,660,184  for the year ended October 31, 1997; this represents a 20% increase
in net  revenues.  The  Company  acquired  MLI in  April  of  1998.  Since  this
acquisition,  for the seven month  period ended  October 31,  1998,  MLI had net
revenues of $7,773,570 or 17% of the Company's net revenues for the year.  There
were no  revenues  from MLI in fiscal  1997.  MLI  provides  routine  laboratory
services  to  physician  offices,   clinics,   nursing  homes  and  correctional
institutions, associated with lower revenues per patient.

The number of  patients  serviced  during the year ended  October  31,  1998 was
984,432  which was 35% greater  when  compared  to the prior  fiscal  year.  MLI
accounted for 24% of the patient count for the year ended October 31, 1998.  Net
revenue per patient for the year ended  October 31, 1997 was $53.08  compared to
net  revenue  per  patient  for the year ended  October  31,  1998 of $47.29;  a
reduction  of $5.79 or 11%.  MLI's net  revenue  per  patient was $33.04 for the
seven month period ended October 31, 1998.

The Company anticipated  increasing its revenues in its next fiscal year through
internal  growth and  development  of new  marketing  initiatives  in laboratory
testing services outside the traditional  physician  market.  In April 1998, the
Company  acquired  MLI and was  awarded,  as of  November,  1998,  a contract to
provide  laboratory  testing by the New York State Department of Corrections for
inmates in its

- ------------------------------------------------------------------------------

Note Regarding Forward-Looking Statements

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

                                       16

<PAGE>



facilities.  The Company is seeking to market its services to other correctional
institutions.  In addition,  the Company is  attempting  to expand its marketing
efforts in the drug testing  market and has hired new marketing  representatives
to specialize in this initiative.

COST OF SERVICES:
- ----------------

Cost of sales increased from  $19,339,274 for the year ended October 31, 1997 to
$25,058,008  for the year ended  October 31, 1998,  an increase of $5,718,734 or
30%. This increase is the result of the MLI acquisition.  MLI's direct operating
costs were  $5,639,627  for the seven month period ended  October 31, 1998.  The
optimum  consolidation of laboratory  operations has not been completed and will
impact the Company's cost structure until completed.

GROSS PROFITS:
- -------------

Gross  profit on net  revenues  increased  from  $19,320,910  for the year ended
October 31, 1997 to $21,495,722 for the year ended October 31, 1998; an increase
of $2,174,812,  primarily attributable to the increase in revenues. Gross profit
margins  decreased  from 50% for the year ended  October 31, 1997 to 46% for the
year ended October 31, 1998.  This decrease in gross profit margins is primarily
attributable to the lower net revenues per patient, the increase in direct costs
associated  with  MLI and the  duplication  of  direct  costs  that had not been
eliminated  as of October 31,  1998 by an optimum  consolidation  of  laboratory
operations.

GENERAL AND ADMINISTRATIVE EXPENSES:
- -----------------------------------

General and  administrative  expenses  for the year ended  October 31, 1998 were
$20,430,757 as compared to  $17,435,879  for the year ended October 31, 1997, an
increase of  approximately  $3,000,000  or 16%. Most of this increase was due to
the incurring of additional costs related to the MLI acquisition  (approximately
$1,858,000).  In addition,  bad debt increased by 11%, or approximately $793,000
over the prior comparable  period and was caused primarily by an increase in the
self-pay  patients of Bio- Reference  Laboratories  resulting  from  legislation
passed  in  New  Jersey  which  prohibited   physician  billing  for  diagnostic
laboratory  services.  Self pay patients have an historical higher bad debt rate
than that of physician billing.

INTEREST EXPENSE:
- ----------------

Interest  expense  increased from $1,124,432 for the year ended October 31, 1997
to $1,280,737 for the year ended October 31, 1998,  resulting from the Company's
increase in asset based  borrowing of  approximately  $4,400,000 and acquisition
debt of $4,000,000 offset by payments on existing debt of $1,000,000.

Liquidity and Capital Resources
- -------------------------------

For the Fiscal Year Ended October 31, 1999
- ------------------------------------------

The Company's working capital at October 31, 1999 was  approximately  $3,700,000
as compared to  approximately  $8,400,000  at October  31,  1998,  a decrease of
$4,700,000.  This  change is  primarily  the  result of a decrease  in  accounts
receivable  of  approximately  $2,000,000,  an increase in accounts  payable and
accrued  expenses  of  approximately  $600,000  and the  utilization  of cash to
decrease long term debt of  approximately  $2,200,000.  The Company  reduced its
debt through the  utilization of its restricted  certificates  of deposit.  This
allowed the Company to realize a cost savings on the spread between the interest
earned on these  certificates of deposit and the interest  expense on the monies
borrowed.

During the year ended  October 31,  1999,  the Company  generated  approximately
$1,800,000 in cash from operations,  an increase of approximately  $5,000,000 as
compared  to the year ended  October 31 1998.  Each  operating  unit of clinical
laboratory testing services generated cash flow during the period ended

- ------------------------------------------------------------------------------

Note Regarding Forward-Looking Statements

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

                                       17

<PAGE>



October  31,  1999.  MLI,  the  Company's  most  recent  laboratory  acquisition
generated   approximately   $600,000  in  cash  from  operating  activities  and
Bio-Reference generated approximately $7,000,000.  Corporate activities (General
and Administrative  Expenses) utilized  approximately  $6,000,000 in cash during
the twelve month period ended  October 31, 1999.  The Company  expects cash flow
from operations to continue to improve during fiscal 2000.  Overall,  Management
anticipates  being able to  generate  cash from  operations  in fiscal 2000 as a
result of a projected  increased gross profit resulting from increased  revenues
and a projected decrease in operating costs. Management believes operating costs
will be lower due to cost savings generated by the automated laboratory and cost
reductions  generated by doing certain large volume  laboratory  tests  in-house
rather than referring them to another laboratory.

Credit risk with respect to accounts receivable is generally  diversified due to
the large number of patients  comprising  the client base. The Company does have
significant  receivable  balances with government  payors and various  insurance
carriers.  Generally,  the Company does not require collateral or other security
to support customer  receivables,  however, the Company continually monitors and
evaluates its client acceptance and collection  procedures to minimize potential
credit risks associated with its accounts  receivable.  The Company  establishes
and  maintains an allowance for  uncollectible  accounts  based upon  collection
history and  anticipated  collection,  and as a  consequence,  believes that its
accounts  receivable  credit risk exposure beyond such allowance is not material
to the financial statements.

A number of proposals  for  legislation  continue to be under  discussion  which
could  substantially  reduce  Medicare and Medicaid  reimbursements  to clinical
laboratories. Depending upon the nature of regulatory action, and the content of
legislation,  the Company could  experience a  significant  decrease in revenues
from Medicare and Medicaid,  which could have a material  adverse  effect on the
Company.  Medicare has announced that it will more than double the reimbursement
rate for Pap tests (from $7.15 to $14.60) and reimburse  for PSA tests  starting
January 1, 2000. The Company is unable to predict,  however, the extent to which
other such  actions will be taken.  (See  "Developments  Since the  Beginning of
Fiscal  1999"  as to  the  status  of a  review  concerning  overpayments  being
conducted by the Company's Medicare carrier and New Jersey Medicaid).

In January 2000, the Company  commenced  negotiations  with New Jersey  Medicaid
regarding a claim (the  "Claim")  made by the State in  December  1999 that with
respect to certain clinical laboratory tests for which  reimbursements were made
by the  State  to the  Company,  although  such  tests  were  authorized  by the
physician,  the underlying  laboratory test requisitions did not bear the actual
signature of the physician ordering the test.

The  Company  believes it has been  compliant  with all  requirements  regarding
claims  submitted for payment by New Jersey  Medicaid and in fact require actual
physician  signatures before it bills New Jersey Medicaid.  However, the Company
and New Jersey Medicaid have entered into an oral agreement in January 2000 to a
settlement  of  approximately  $227,000  to cover the claim and the  Company has
accrued this settlement amount in its October 31, 1999 financial statements. The
settlement is subject to the parties'  execution of a written  agreement setting
forth its terms and to the  approval of the  Director of the Division of Medical
Assistance. Approval of the settlement is being recommended to the Director.

New  Jersey  Medicaid  is the only payor the  Company  does  business  with that
requires an actual physician signature on every laboratory  requisition.  In the
fiscal  year  ending   October  31,  1999,  New  Jersey   Medicaid   represented
approximately 3% of the Company's total net revenues.

In April 1998,  the Company  amended its revolving loan agreement with PNC Bank.
The maximum  amount of the credit line available to the Company is the lesser of
(1) $14,000,000 or (ii) 50% of the Company's  qualified accounts  receivable [as
defined in the  agreement]  plus 1% of any face  amount of the  certificates  of
deposit,  if any,  pledged as  collateral  for this loan minus the amount of any
portion of the outstanding principal balance of the term loan which is deemed to
be collateralized by the certificates of deposit. Interest on advances which are
collateralized by certificates of deposit will be at 2% above the certificate of
deposit  interest rate.  Interest on other advances will be at prime plus 1.25%.
The credit line

- ------------------------------------------------------------------------------

Note Regarding Forward-Looking Statements

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

                                       18

<PAGE>



is  collateralized  by  substantially  all  of  the  Company's  assets  and  the
assignment of a $4,000,000  insurance policy on the life of the president of the
Company.  The line of credit is available through March 2001 and may be extended
for annual  periods by mutual  consent  thereafter.  The terms of this agreement
contain, among other provisions,  requirements for maintaining defined levels of
capital  expenditures  and net worth,  various  financial  ratios and  insurance
coverage.  As of October  31,  1998,  the  Company  was in  compliance  with the
covenant  provisions of this  agreement and was  utilizing  $12,000,000  of this
credit  facility.  As of October 31, 1999, the Company was in default of certain
covenants, however, the Company subsequently received waivers for these defaults
on  January  20,  2000.  As of October  31,  1999,  the  Company  was  utilizing
$8,700,905 of this credit facility.

The  Company  generated  approximately  $5,000,000  of  positive  cash flow from
operating and investing  activities  for the year ended October 31, 1999,  which
was applied toward payments  totaling  approximately  $5,800,000 to reduce short
and long term debt and capital lease obligations.

The Company intends to expand its laboratory operations through acquisitions and
aggressive marketing while also diversifying into related medical fields through
acquisitions.  These acquisitions may involve cash, notes,  common stock, and/or
combinations thereof

The Company has various  employment  and  consulting  agreements  of up to seven
years with commitments totaling  approximately  $5,700,000 [See Notes 10 and 12]
and operating  leases with  commitments  totaling  approximately  $4,500,000 (of
which approximately  $1,5600,000 and $1,600,000 are due during fiscal 2000) [See
Note 12].

The Company's cash balances at October 31, 1999 totaled approximately $2,100,000
as compared to  $2,800,000  at October 31, 1998.  The Company  believes that its
cash  position,  the  anticipated  cash generated  from future  operations,  the
availability  of its credit line with PNC Bank, the  utilization of certificates
of  deposits  maturing  during  the second  quarter of fiscal  year 2000 and the
interest due thereupon, will meet its future cash needs.

For the Fiscal Year Ended October 31, 1998

Working capital at October 31, 1998 was approximately  $8,400,000 as compared to
approximately  $9,400,000 at October 31, 1997, a decrease of  $1,100,000  during
the twelve month period.

In fiscal  year 1998,  the Company  utilized  $3,227,601  in cash for  operating
activities. This use of cash for operating activities resulted in an increase in
accounts  receivable  of  approximately  $7,200,000  offset by the  increase  in
accrued expenses and payables of approximately $2,600,000.

The Company utilized  $4,237,998 of cash for investing  activities during fiscal
year 1998. This consisted primarily of $4,000,000 of cash paid for Medilabs.

Impact of Inflation
- -------------------

To date, inflation has not had a material effect on the Company's operations.

New Authoritative Pronouncements
- --------------------------------

The Financial  Accounting Standards Board ("FASB") issued Statement of Financial
Accounting  Standards ("SFAS") No. 137,  "Accounting for Derivative  Instruments
and Hedging  Activities-Deferral  of Effective Date of FASB Statements No. 133."
The Statement  defers for one year the effective date of FASB Statement No. 133,
"Accounting  for Derivative  Instruments and Hedging  Activities."  The rule now
will apply to all fiscal  quarters of all fiscal years  beginning after June 15,
2000. The Statement will require the Company to recognize all derivatives on the
balance sheet at fair value. Derivatives that are not hedges must be adjusted to
fair value through income. If the derivative is a hedge,  depending on the value
of the hedged  assets,  liabilities,  or firm  commitments  through  earnings or
recognized in other

- ------------------------------------------------------------------------------

Note Regarding Forward-Looking Statements

This  Annual  Report on Form 10-K  contains  historical  information  as well as
forward-looking  statements.  Statements looking forward in time are included in
this Annual  Report  pursuant  to the "safe  harbor"  provisions  of the Private
Securities  Litigation  Reform Act of 1995.  Such  statements  involve known and
unknown risks and  uncertainties  that may cause the Company's actual results in
future periods to be materially different from any future performance  suggested
herein.

                                       19

<PAGE>



comprehensive  income  until the hedged  item is  recognized  in  earnings.  The
ineffective  portion of a derivative's  change in fair value will be immediately
recognized  in earnings.  The adoption of SFAS No. 137 is not expected to have a
material impact on the Company's  consolidated  results of operation,  financial
position or cash flows.

Item 7A. Quantitative and Qualitative Disclosure About Market Risk
         ---------------------------------------------------------

      Not applicable.

Item 8. -  Financial Statements and Supplementary Data
           -------------------------------------------

      Financial Statements are annexed hereto

Item 9. -  Changes in and Disagreements with Accountants on Accounting and
           Financial Disclosure
           ---------------------------------------------------------------------

      None



                                       20

<PAGE>



                                    PART III

Item 10.- Directors and Executive Officers of the Registrant
          --------------------------------------------------

      The following table sets forth certain information with respect to each of
the directors and executive officers of the Company.

      Name                       Age   Position

Marc D. Grodman, M.D.............48    Chairman of the Board, President, Chief
                                       Executive Officer and Director

Howard Dubinett..................48    Executive Vice President, Chief Operating
                                       Officer and Director

Sam Singer.......................57    Vice President, Chief Financial Officer,
                                       Chief Accounting Officer and Director

Frank DeVito.....................77    Director

John Roglieri, M.D...............60    Director

Gary Lederman, Esq...............65    Director

      Marc D.  Grodman,  M.D.  founded the Company in December 1981 and has been
its Chairman of the Board,  President,  Chief  Executive  Officer and a Director
since its formation.  Dr. Grodman is an Assistant Professor of Clinical Medicine
at  Columbia  University  College  of  Physicians  and  Surgeons  and  Assistant
Attending Physician at Presbyterian  Hospital, New York City. From 1980 to 1983,
Dr. Grodman attended the Kennedy School of Government at Harvard  University and
was a Primary Care Clinical Fellow at Massachusetts General Hospital.  From 1982
to 1984,  he was a medical  consultant  to the Metal  Trades  Department  of the
AFL-CIO.  Dr. Grodman received a B.A. degree from the University of Pennsylvania
in 1973 and an M.D.  degree from Columbia  University  College of Physicians and
Surgeons in 1977. Except for approximately 20 hours per month spent as Assistant
Professor of Clinical  Medicine and  Assistant  Attending  Physician at Columbia
University  and  Presbyterian  Hospital and  rendering  medical  services to the
Uniformed Firefighters  Association of New York City, Dr. Grodman devotes all of
his working time to the business of the Company.

      Howard Dubinett has been the Executive  Vice-President and Chief Operating
Officer of the Company since its formation.  He became a Director of the Company
in April 1986. Prior to joining the Company, Mr. Dubinett was general manager of
Union Prescription Service, Inc., a company which administered prescription drug
plans. Mr. Dubinett attended Rutgers University. Mr. Dubinett devotes all of his
working time to the business of the Company.

      Sam Singer  has been the  Company's  Vice  President  and Chief  Financial
Officer since October 1987 and a Director since November 1989. He is responsible
for all financial  activities of the Company.  Prior to joining the Company,  he
was Controller for Sycomm Systems Corporation,  a data processing and management
consulting  company,  from 1981 to 1987. He received a B.A.  degree from Strayer
College and an M.B.A.  from Rutgers  University.  Mr. Singer  devotes all of his
working time to the business of the Company.

      Frank DeVito  became a Director of the Company in April 1986.  Since 1970,
Mr. DeVito has been Vice President of the New Jersey State AFL-CIO and from 1960
until December 1985 was President of AFL-CIO United Food and Commercial Workers,
Local 1245.  From 1981 through  December 1985 Mr.  DeVito was also  President of
United Food and Commercial Workers District Council of Metropolitan New York and
Northern New Jersey,  which was comprised of 35 local unions with  approximately
150,000 members.

      John Roglieri, M.D. became a Director of the Company in September 1995. He
is an Assistant Professor of Clinical Medicine at Columbia  University's College
of Physicians and Surgeons and an Assistant  Attending Physician at Presbyterian
Hospital, New York City. Dr. Roglieri received a B.S.

                                       21

<PAGE>



degree in Chemical Engineering and a B.A. degree in Applied Sciences from Lehigh
University in 1960, an M.D.  degree from Harvard  Medical  School in 1966, and a
Master's degree from Columbia  University  School of Business in 1978. From 1969
until 1971, he was a Senior Assistant  Surgeon in the U.S. Public Health Service
in  Washington.  From 1971 until 1973 he was a Clinical and  Research  Fellow at
Massachusetts  General  Hospital.  From 1973 until 1975,  he was Director of the
Robert Wood Johnson Clinical Scholars program at Columbia University. In 1975 he
was appointed  Vice-President  Ambulatory Services at Presbyterian  Hospital,  a
position  which he held until 1980.  Since  1980,  he has  maintained  a private
practice of internal medicine at Columbia-Presbyterian Medical Center. From 1988
until 1992, he was also Director of the Employee  Health Service at Presbyterian
Hospital.  Since 1992,  he has been  Corporate  Medical  Director of NYLCare,  a
managed care  subsidiary of New York Life. He is a member of advisory  boards to
several  pharmaceutical  companies,  a member of the Editorial Advisory Board of
the journal Managed Care and a biographee of Who's Who in America.

      Gary  Lederman,  Esq.  became a director  of the  Company in May 1997.  He
received his B.A. from Brooklyn College in 1954 and his J.D. from NYU Law School
in 1957. He was manager of Locals 370, 491 and 662 of the U.F.C.W. International
Union from 1961 to 1985.  He is retired  from the unions and has been a lecturer
at Queensboro  Community College in the field of insurance.  He currently serves
on an  institutional  review  board  for  RTL,  a  pharmaceutical  drug  testing
laboratory.

      There are no  family  relationships  between  or among  any  directors  or
executive  officers of the Company.  The Company's  Certificate of Incorporation
provides for a staggered Board of Directors (the "Board")  pursuant to which the
Board is divided  into three  classes of  directors  and the members of only one
class or  one-third  of the Board) are elected  each year to serve a  three-year
term.  Officers are elected by and hold office at the discretion of the Board of
Directors.

Key Personnel and Consultants
- -----------------------------

      The following key personnel and consultants make significant contributions
to the Company's operations.

      Robert  Rush,  Ph.D (Age 59) has been  employed by the Company  since July
1993 as Vice President of Technical Operations.  From 1989 to 1993, Dr. Rush was
a Technical Director for National Health Laboratories, Inc., a national clinical
laboratory.  From 1988 to 1989 he was the Technical Director of Maryland Medical
Laboratory  and from 1975 to 1988 he was the Technical  Director of  Smith-Kline
Beecham Clinical Laboratories,  another national clinical testing laboratory, in
Atlanta,   Georgia.   Dr.  Rush  also  worked  for  the  Technicon   Instruments
Corporation,  a Tarrytown,  New York manufacturer of laboratory equipment,  from
1969 to 1972, as a Section Head in Clinical Chemistry.  Dr. Rush is a registered
Clinical  Laboratory  Director  in  the  states  of New  Jersey,  New  York  and
Connecticut.  He is board certified by the American Board of Clinical Chemistry.
Dr. Rush  received a B.A.  degree in Chemistry  from Hunter  College in 1962 and
M.S. and Ph.D.  degrees in Biochemistry in 1964 and 1966 from Pennsylvania State
University.

      Benita  Ponda,  M.D.  (Age  54) has been  employed  by the  Company  since
February,  1994 as Medical  Director.  She is certified by the American Board of
Pathology  in  Clinical  Pathology  and  Anatomical  Pathology  with  a  special
qualification in Cytopathology.  She holds a New York State Department of Health
Certificate of Qualification for Laboratory  Director.  Dr. Ponda's professional
appointments  include Chief of  Cytopathology  and Associate  Pathologist at New
York Methodist Hospital,  Brooklyn,  New York (January 1992 to February,  1994);
Associate  Pathologist at Flushing  Hospital and Medical Center,  Flushing,  New
York (1981 to 1991) and  Director  of  Laboratory  at St.  Mary's  Hospital  for
Children (1985 - to date). She received M.B.B.S.  degree  (equivalent to M.D. in
U.S.A.) from Bombay University, Bombay, India in 1970.

      Ayad  Mudarris,  Ph.D.  (Age 48) has been  employed by the  Company  since
February  1996 as an Assistant  Director of Technical  Operation and Director of
Toxicology.  Dr.  Mudarris has been a consultant  to the Company  since  October
1994.  From 1992 to 1994,  Dr.  Mudarris  was a Technical  Director for National
Health  Laboratories,  a national clinical  laboratory located in Cranford,  New
Jersey.  From  1988 to 1992 he was  Vice  President  and  Director  of  Columbia
Biomedical   Laboratory,   A  SAMHSA  (NIDA)  certified  forensic  drug  testing
laboratory in Columbia,  South Carolina, and from 1987 to 1988 as Scientific and
Managing Director of Keystone Laboratory,  a toxicology laboratory in Asheville,
North Carolina. Dr. Mudarris is a registered Clinical Laboratory Director in the
State of New

                                       22

<PAGE>



York.  He is  certified  by the  American  Board of  Bioanalysis  as a  Clinical
Laboratory  Director  and by the  National  Registry of Clinical  chemistry as a
Clinical  chemist.  He  received  his B.S.  degree  in  Pharmacy  from  Damascus
University  in 1975 and M.S.  degree in  Medical  Technology  from  Long  Island
University  in 1980 and Ph.D.  degree in  Biochemistry  from the  University  of
Arkansas for Medical Sciences in 1986.

Compliance with Section 16(a) of the Exchange Act
- -------------------------------------------------

      Based  solely  on a  review  of Forms 3 and 4 and any  amendments  thereto
furnished to the Company pursuant to Rule 16a-3(e) under the Securities Exchange
Act of 1934,  or  representations  that no Forms 5 were  required,  the  Company
believes  that  with  respect  to  fiscal  1999,  its  officers,  directors  and
beneficial  owners  of more  than 10% of its  equity  timely  complied  with all
applicable Section 16(a) filing requirements.

Item 11. - Executive Compensation
           ----------------------

      The following  table sets forth  information  concerning the  compensation
paid or accrued by the Company  during the year ended on October 31, 1999 to its
Chief  Executive  Officer and its other  executive  officers who were serving as
executive  officers  of the Company on October 31,  1999.  All of the  Company's
group life, health,  hospitalization or medical  reimbursement plans, if any, do
not  discriminate  in  scope,  terms or  operation,  in  favor of the  executive
officers or directors of the Company and are generally available to all salaried
employees.
<TABLE>

                           SUMMARY COMPENSATION TABLE
                                                                               Long-Term
                                                                               ---------
                                    Annual Compensation                     Compensation
                                    -------------------                     ------------

                                                            Other                               All
                                Year                        Annual  Restricted         LTIP    Other
                               Ended                        Compen-  Stock     Options Pay-   Compen-
Name and Principal Position October 31, Salary     Bonus    sation  Awards(1)  (SARs)  outs   sation
- ---------------------------------------------------------------------------------------------------

<S>                            <C>     <C>       <C>        <C>    <C>      <C>         <C>   <C>
Marc D. Grodman M.D.           1999    $306,557  $125,000   $-0-       -0-      -0-     $-0-  $-0-
   President and Chief         1998    $305,653  $125,000   $-0-       -0-      -0-     $-0-  $-0-
   Executive Officer           1997    $265,697   $90,000   $-0-   300,000  300,000(2)  $-0-  $-0-

  Howard Dubinett              1999    $160,004   $60,000   $-0-       -0-      -0-     $-0-  $-0-
   Executive Vice              1998    $157,622   $57,750   $-0-       -0-      -0-     $-0-  $-0-
   President and Chief         1997    $148,417   $43,000   $-0-   240,000  213,334     $-0-  $-0-
   Operating Officer

  Sam Singer                   1999    $158,002   $60,000   $-0-       -0-      -0-     $-0-  $-0-
   Vice President and          1998    $156,333   $57,750   $-0-       -0-      -0-     $-0-  $-0-
   Chief Financial and         1997    $147,455   $43,000   $-0-   200,000  116,667     $-0-  $-0-
   Accounting Officer
</TABLE>

(1) In  connection  with  their  acceptance  of  the  terms  of  new  employment
agreements,  the  Company's  board of directors on May 13, 1997  authorized  the
issuance to Dr.  Grodman,  Mr.  Dubinett and Mr. Singer of 300,000,  240,000 and
200,000 shares of Common Stock respectively.  The shares are forfeitable in part
in various amounts if the employee's  employment is terminated "for cause" or at
his  option  "without  good  reason"  prior  to May  1,  2000.  See  "Employment
Agreements with Executive Officers" herein.

(2) Does not include  604,078 shares of Common Stock issuable upon conversion of
604,078 shares of Senior  Preferred Stock owned by Dr.  Grodman,  his wife and a
corporation  controlled by her (collectively  the "Grodman  Group").  On May 13,
1997 pursuant to a recapitalization, the previously outstanding Senior Preferred
Stock owned by the Grodman Group convertible into an aggregate 604,078 shares of
Common  Stock on or before  April 20,  2003 at a  conversion  price of $1.50 per
share  was  retired  in  exchange  for a new  class of  Senior  Preferred  Stock
convertible into an aggregate 604,078 shares of Common Stock on or before May 1,
2007 at a conversion price of $.75 per share. See Item 13 herein.

Employment Agreements with Executive Officers
- ---------------------------------------------

      On May 13,  1997,  Dr.  Grodman  agreed to the  terms of a new  employment
agreement  pursuant  to which he will  serve as  president  and chief  executive
officer  devoting  at  least  90% of his  working  time to the  business  of the
Company. The agreement provides (I) for a seven-year term commencing November 1,
1997; (ii) a minimum annual Base Compensation  consisting of salary and bonus in
the aggregate  amount of $395,000 subject to increases based on increases in the
Consumer  Price Index as well as  increases  at the  discretion  of the board of
directors;  (iii) typical health  insurance  coverage and an initial  $2,000,000
face amount of "split  dollar" life  insurance  insuring Dr.  Grodman's life and
payable to his estate  (excluding  benefits  required  to be paid to the Company
pursuant to the split dollar plan) with $2,000,000 of additional  coverage to be
applied for, which was obtained during fiscal 1999; (iv) the

                                       23

<PAGE>



leasing of an  automobile  for his use;  (v)  participation  in fringe  benefit,
bonus,  pension,  profit sharing, and similar plans maintained for the Company's
employees;  (vi) disability benefits;  (vii) certain termination  benefits;  and
(viii) in the event of termination due to a change in control of the Company,  a
severance payment equal to 2.99 times Dr. Grodman's average annual  compensation
during the preceding five years.

      In  consideration  for  Dr.  Grodman's  acceptance  of  the  terms  of the
employment  agreement,  the board of  directors  authorized  the issuance to Dr.
Grodman of (a) 300,000 shares of the Company's Common Stock,  partially  subject
to forfeiture,  (b) five-year  incentive stock options  ("ISOs")  exercisable to
purchase  100,000 shares of Common Stock at $.790625 per share, and (C) ten-year
non-qualified  stock options ("NQOs")  exercisable to purchase 200,000 shares of
Common  Stock at $.71875  per  share.  The ISOs are only  exercisable  while Dr.
Grodman is employed by the Company.  The NQOs expire if Dr. Grodman's employment
agreement is  terminated  by the Company "For Cause" or at his option,  "Without
Good Reason." See "Employee Incentive Stock Option Plan."

      The 300,000 shares of Common Stock issued to Dr.  Grodman are  forfeitable
in part on the following basis if his employment  agreement is terminated by the
Company "For Cause" or at Dr.
Grodman's option "Without Good Reason."


     If Termination "For Cause"
      or "Without Good Reason"
    Occurs During the Following        Number of Shares
              Periods                     Forfeited
- ---------------------------------      -----------------

May 1, 1997 through April 30, 1998           225,000 shs.
May 1, 1998 through April 30, 1999           150,000 shs.
May 1, 1999 through April 30, 2000            75,000 shs.

      Also on May 13, 1997, Mr. Dubinett agreed to the terms of a new employment
agreement  pursuant to which he will serve as executive vice president and chief
operating  officer of the  Company.  The  agreement  provides (I) for a five and
one-half  year  term  commencing  May  1,  1997;  (ii)  a  minimum  annual  Base
Compensation  commencing  November 1, 1997 consisting of salary and bonus in the
aggregate  amount of $220,000  subject to  increases  based on  increases in the
Consumer  Price Index as well as  increases  at the  discretion  of the board of
directors;  (iii) typical health insurance  coverage and $500,000 face amount of
"split dollar" life insurance  insuring Mr.  Dubinett's  life and payable to his
estate  (excluding  benefits  required to be paid to the Company pursuant to the
split dollar  plan)which  amount was increased to $1,000,000 during fiscal 1999;
(iv) the  leasing of an  automobile  for his use;  (v)  participation  in fringe
benefit,  bonus,  pension,  profit sharing, and similar plans maintained for the
Company's  employees;   (vi)  disability  benefits;  (vii)  certain  termination
benefits;  and (viii) in the event of termination  due to a change in control of
the Company,  a severance  payment  equal to 2.99 times Mr.  Dubinett's  average
annual compensation during the preceding five years.

      In  consideration  for  Mr.  Dubinett's  acceptance  of the  terms  of the
employment  agreement,  the board of  directors  authorized  the issuance to Mr.
Dubinett of (a) 240,000 shares of the Company's Common Stock,  partially subject
to forfeiture  and (b) ten-year ISOs  exercisable  to purchase  60,000 shares of
Common  Stock at $.71875  per  share.  The ISOs are only  exercisable  while Mr.
Dubinett is employed by the Company.

      The 240,000 shares of Common Stock issued to Mr. Dubinett. are forfeitable
in part on the following basis if his employment  agreement is terminated by the
Company "For Cause" or at Mr. Dubinett's option "Without Good Reason."


                                       24

<PAGE>





     If Termination "For Cause"
      or "Without Good Reason"
    Occurs During the Following         Number of Shares
              Periods                      Forfeited
- ----------------------------------    ---------------------

May 1, 1997 through April 30, 1998           180,000 shs.
May 1, 1998 through April 30, 1999           120,000 shs.
May 1, 1999 through April 30, 2000            60,000 shs.

      Also on May 13, 1997,  Mr. Singer agreed to the terms of a new  employment
agreement  pursuant to which he will serve as vice president and chief financial
officer of the Company.  The agreement provides (I) for a five and one-half year
term commencing May 1, 1997; (ii) a minimum annual Base Compensation  commencing
November  1, 1997  consisting  of salary  and bonus in the  aggregate  amount of
$220,000  subject to increases based on increases in the Consumer Price Index as
well as increases at the  discretion  of the board of  directors;  (iii) typical
health  insurance  coverage  and  $400,000  face amount of "split  dollar"  life
insurance  insuring  Mr.  Singer's  life and  payable to his  estate  (excluding
benefits  required to be paid to the Company  pursuant to the split dollar plan)
which amount was increased to $800,000 in November 1999;  (iv) the leasing of an
automobile for his use; (v)  participation  in fringe benefit,  bonus,  pension,
profit sharing, and similar plans maintained for the Company's  employees;  (vi)
disability benefits; (vii) certain termination benefits; and (viii) in the event
of termination  due to a change in control of the Company,  a severance  payment
equal  to 2.99  times  Mr.  Singer's  average  annual  compensation  during  the
preceding five years.

      In  consideration  for  Mr.  Singer's  acceptance  of  the  terms  of  the
employment  agreement,  the board of  directors  authorized  the issuance to Mr.
Singer of (a) 200,000 shares of the Company's Common Stock, partially subject to
forfeiture and (b) ten-year ISOs exercisable to purchase 50,000 shares of Common
Stock at $.71875 per share.  The ISOs are only  exercisable  while Mr. Singer is
employed by the Company.

      The 200,000 shares of Common Stock issued to Mr. Singer are forfeitable in
part on the  following  basis if his  employment  agreement is terminated by the
Company "For Cause" or at Mr. Singer's option "Without Good Reason."


      If Termination "For Cause"
       or "Without Good Reason"
     Occurs During the Following        Number of Shares
               Periods                      Forfeited
- --------------------------------------  --------------------

May 1, 1997 through April 30, 1998        150,000 shs.
May 1, 1998 through April 30, 1999        100,000 shs.
May 1, 1999 through April 30, 2000         50,000 shs.

Employee Stock Option Plan
- --------------------------

      In July 1989, the Company's Board of Directors  adopted the 1989 Employees
Stock  Option  Plan (the "1989  Plan")  which was  approved by  shareholders  in
November 1989. The 1989 Plan provides for the grant of options to purchase up to
666,667  shares of Common  Stock.  Under  the  terms of the 1989  Plan,  options
granted  thereunder  may be  designated  as options  which qualify for incentive
stock option treatment  ("ISOs") under Section 422 of the Code, or options which
do not so qualify ("NQOs").

      The 1989 Plan also grants the Board or a Stock Option Committee designated
by the Board,  the  discretion to grant stock  appreciation  rights  ("SARs") in
connection  with, or  independent  of, any grant of options under the 1989 Plan.
SARs give the holder the right to receive  from the  Company  upon  exercise  an
amount  equal to the excess of the  aggregate  fair market  value on the date of
exercise  of the  number of shares  of Common  Stock as to which  SARs are being
exercised  over the aggregate  exercise price for those shares payable either in
cash or  Common  Stock  in the  discretion  of the  Board  or the  Stock  Option
Committee.

                                       25

<PAGE>



      The 1989 Plan is administered by the Board or by a Stock Option  Committee
designated by the Board of Directors.  The Board or the Stock Option  Committee,
as the case may be, has the  discretion to determine  the eligible  employees to
whom,  and the times and the price at which,  options  will be granted;  whether
such options  shall be ISOs or NQOs;  the periods  during which  options will be
exercisable;  and the  number of shares  subject  to each  option.  The Board or
Committee  shall have full authority to interpret the 1989 Plan and to establish
and amend rules and regulations relating thereto.

      Under the 1989 Plan, the exercise price of an option  designated as an ISO
shall not be less than the fair market value of the Common Stock on the date the
option is  granted.  However,  in the event an  option  designated  as an ISO is
granted to a 10%  shareholder  (as defined in the 1989 Plan) such exercise price
shall be at least  110% of such  fair  market  value.  Exercise  prices  of NQOs
options may be less than such fair market value. The aggregate fair market value
of shares  subject to options  granted to a participant  which are designated as
ISOs  which  first  become  exercisable  in any  calendar  year  may not  exceed
$100,000.

      As  described  above,  on May 13,  1997,  the Board of  Directors  granted
five-year ISOs under the Plan to Dr.  Grodman,  exercisable to purchase  100,000
shares of the Company's  Common Stock at an exercise price of $.790625 per share
(equal to 110% of the last sale price for the Common  Stock on NASDAQ on May 12,
1997).  The board also granted  ten-year ISOs under the Plan to Mr. Dubinett and
Mr.  Singer  exercisable  to purchase  60,000 shares and 50,000 shares of Common
Stock  respectively at an exercise price of $.71875 per share (equal to the last
sale price for the Common Stock on NASDAQ on May 12,  1997).  In  addition,  the
board granted  ten-year NQOs to Dr.  Grodman,  exercisable  to purchase  200,000
shares of Common Stock at an exercise price of $.71875 per share.

      At the same May 3, 1997 directors'  meeting,  in order to improve employee
morale, the board canceled all other outstanding ISOs exercisable to purchase an
aggregate 448,710 shares of Common Stock at exercise prices ranging from $1.3434
to $3.00 per share, and granted new ten-year ISOs under the Plan to 23 employees
exercisable  to  purchase  an  aggregate  448,710  shares of Common  Stock at an
exercise price of $.71875 per share.  Included in this grant were ISOs issued to
Mr. Dubinett and Mr. Singer  exercisable to purchase  153,334 shares and 116,667
shares  respectively.  (These ISOs replaced ISOs previously  granted to said two
individuals  to purchase  153,334  shares and  116,667  shares  respectively  at
exercise prices ranging from $1.3125 to $1.50 per share.)

      Also on May 13, 1997, the Board of Directors  granted five-year NQOs to 31
employees,  exercisable to purchase an aggregate  136,100 shares of Common Stock
at $.71875 per share but only while the optionee was employed by the Company.

      On May 13, 1997, the board also issued  five-year  warrants to each of its
three outside  directors,  exercisable to purchase  10,000 shares (30,000 in the
aggregate) of Common Stock at an exercise  price of $.71875 per share,  but only
while  serving as a director.  At the same time,  the board reduced the exercise
price on warrants held by one outside  director,  John Roglieri,  exercisable to
purchase  23,334  shares  ranging  from  $3.00  per  share to $3.75 per share to
$.71875 per share and issued  five-year  warrants to another  outside  director,
Gary Lederman, exercisable to purchase 5,200 shares at $.71875 per share.


      No stock options were granted during fiscal 1998. On January 19, 1999, the
Board  of  Directors  granted  five-year  NQOs to 15  employees  exercisable  to
purchase an aggregate  286,000  shares of Common  Stock at an exercise  price of
$1.00 per  share  (the last  sale  price for the  Common  Stock on NASDAQ on the
trading day  immediately  preceding the meeting) but only while the optionee was
employed by the  Company.  On June 30,  1999,  the Board  ratified  the grant of
five-year NQOs to three employees,  exercisable to purchase an aggregate 150,000
shares of Common Stock at prices  ranging from $.594 to $.719 per share but only
while the optionee was employed by the Company.  The option prices were based on
the market prices for the Common Stock on the respective  dates when  employment
commenced for each of the three employees.

      See Note 9 of Notes to the Consolidated Financial Statements.

      The following table sets forth certain information  concerning unexercised
options for each of the executive  officers  named in the "Summary  Compensation
Table." No options were exercised by any of such individuals in fiscal 1999.

                                       26

<PAGE>



                       1999 Fiscal Year-End Option Values
                       ----------------------------------


                      Number of Unexercised Options        Value of
                         At 1999 Fiscal Year-End         Unexercised
                                                         In-The-Money
Name               Exercisable                        Options at 10/31/99
- ----               -----------                        -------------------
                                        Unexercisable
                                        -------------
Marc D. Grodman    200,000                    -0-     $      50,000
                   100,000                    -0-     $      17,813

Howard Dubinett    213,334                    -0-     $      53,333
Sam Singer         166,667                    -0-     $      41,667

Directors' Compensation
- -----------------------

      Directors  who are not employees of the Company are also paid a $1,000 per
quarter director's fee.

Item 12. - Security Ownership of Certain Beneficial Owners and Management
           --------------------------------------------------------------

      The  following  table sets forth  information  as of January 21, 1999 with
respect to the ownership of Common Stock by (I) each person known by the Company
to be the beneficial owner of more than 5% of its outstanding Common Stock, (ii)
each director of the Company,  (iii) each executive officer of the Company,  and
(iv) all directors and executive  officers as a group. The percentages have been
calculated on the basis of treating as outstanding for a particular  holder, all
shares of Common  Stock  outstanding  on said date owned by such holders and all
shares of Common  Stock  issuable  to such  holder in the event of  exercise  or
conversion of outstanding options,  warrants and convertible securities owned by
such holder at said date which are exercisable or convertible  within 60 days of
such date.

                                                                      Shares of
         Name and Address of                      Common Stock       Percentage
         Beneficial Owner                    Beneficially Owned(1)    Ownership
         ----------------                    ---------------------    ---------

Directors and Executive Officers*
      Marc D. Grodman(2)...........................1,673,845             18.6%
      Howard Dubinett (3)............................477,001              5.7%
      Sam Singer(4)..................................377,667              4.6%
      Frank DeVito(5)................................ 10,202               -
      John Roglieri(6)............................... 31,667               -
      Gary Lederman (7).............................. 25,200               -

      Executive Officers and directors.............2,595,582             27.5%
        as a group (six persons)(2)(3)(4)(5)(6)(7)


*     The address of all of the Company's  directors and ex ecutive  officers is
      c/o the  Company,  481  Edward H. Ross  Drive,  Elmwood  Par k, New Jersey
      07407.

                                       27

<PAGE>



(1)   Except otherwise noted, each holder named in the table has sole voting and
      investment  power  with  respect to all  shares of Common  Stock  shown as
      beneficially owned.

(2)   Includes  608,100  shares owned  directly by Dr.  Grodman,  549,678 shares
      issuable upon  conversion  of Senior  Preferred  Stock and 300,000  shares
      issuable upon  exercise of options.  Also  includes  121,667  shares owned
      directly and 54,400 shares  issuable upon  conversion of Senior  Preferred
      Stock held by Dr. Grodman's wife, Pam Grodman, and a Company controlled by
      her and 40,000 shares owned by their minor children. Dr. Grodman disclaims
      beneficial ownership of these 236,067 shares.

(3)   Includes  263,667shares  owned directly,  and 213,334 shares issuable upon
      exercise of options.

(4)   Includes  211,000 shares owned directly,  and 166,667 shares issuable upon
      exercise of options.

(5)   Includes  202 shares  owned  directly  and  10,000  shares  issuable  upon
      exercise of warrants.

(6)   Includes  1,667 shares  owned  directly and 30,000  shares  issuable  upon
      exercise of warrants.

(7)   Includes 25,200 shares owned directly.

Item 13. - Certain Relationships and Related Transactions
           -----------------------------------------------

      In July 1989,  the Company  discontinued  the operation of its  Med-Mobile
Division. At such time, Dr. Grodman, as the Associated  Physician,  was indebted
to the Company in the amount of $235,354 in  connection  with the  operation  of
this division.  Pursuant to an October 1, 1989 Settlement Agreement, Dr. Grodman
issued a $235,354  promissory  note to the Company  bearing  interest at 10% per
annum  and  payable  at the  rate  of  $50,000  per  annum  in  payment  of this
indebtedness.  On April 30, 1992, the Board of Directors amended this agreement,
in  consideration  for  Dr.  Grodman's   personal  guarantee  of  the  Company's
$2,500,000 financing arrangement with Towers Financial  Corporation,  suspending
all rental and interest  charges for periods  subsequent to November 1, 1991. As
of October 31, 1999, $138,518 in outstanding principal, interest and van rentals
was due from Dr. Grodman.

      On April 20, 1993,  in order to  facilitate  the  Company's  1993 proposed
public  offering,  Dr.  Grodman  canceled his pro-rata  option  contained in his
employment  contract and all other outstanding  options and warrants to purchase
shares of Common Stock held by Dr.  Grodman,  his wife and an affiliated  entity
(the "Grodman  Group")  exercisable  to purchase an aggregate  604,078 shares of
Common  Stock at prices  ranging  from  $1.4438 to $1.50 or an average  price of
$1.47 per share,  in  consideration  for the  issuance to the  Grodman  Group of
604,078  shares  of a new class of senior  preferred  stock,  $.10 par value per
share ("Senior Preferred  Stock").  Each share of Senior Preferred Stock had the
same voting rights (one vote per share),  dividend rights and liquidation rights
as each share of Common Stock and for a period of 10 years after  issuance,  was
convertible into one share of Common Stock upon payment of a conversion price of
$1.50 per share. The 604,078 shares of Senior Preferred Stock were issued to the
Grodman Group on August 23, 1993.

      On May 13, 1997 pursuant to a  recapitalization,  the Senior Preferred was
retired in  exchange  for a new class of Senior  Preferred  Stock  issued to the
Grodman Group.  The new Senior  Preferred Stock is convertible into an aggregate
604,078 shares of Common Stock on or before May 1, 2007 at a conversion price of
$.75 per share and has the same voting  rights  (one vote per  share),  dividend
rights and liquidation rights as each share of Common Stock.


                                       28

<PAGE>




Item 14. Exhibits, Financial Statement Schedules and Reports on Form 10-KSB
         ------------------------------------------------------------------

1.    Financial Statements

      The following financial statements of the Company are included in
      Part II, Item 7

                                                                  Page to Page
                                                                  ------------

      Report of Independent Certified Public Accountants          F-1

      Balance Sheet - October 31, 1999 and 1998                   F-2..F-3

      Statement of Operations-
        Years ended October 31, 1999, 1998 and 1997               F-4

      Statement of Shareholders' Equity
        Years ended October 31, 1999, 1998 and 1997               F-5

      Statement of Cash Flows -
        Years ended October 31, 1999, 1998 and 1997               F-6..F-7

      Notes to Financial Statements-                              F-8..F-23

      Schedule II -
        Years ended October 31, 1999, 1998 and 1997               F-24.F-25

2.    Reports on Form 8-K

      No reports on Form 8-K have been filed  during the Quarter  ended  October
31, 1999.

3.    Exhibits
Exhibit                                                          Incorporated by
  No.                 Item                                          Reference to

3.1*     Amended and Restated Certificate of Incorporation dated         (A)
         November 15, 1989

3.1.1*   Amendment to Certificate of Incorporation dated                 (B)
         October 4, 1991 (authorizing one-for-10 reverse stock split)

3.1.2*   Amendment to Certificate of Incorporation dated                 (C)
         August 23, 1993 (authorizing one-for-three reverse stock split)

3.1.3    Amendment to Certificate of Incorporation dated March 23, 1998
         (creating Series A Senior Preferred Stock)

3.1.4    Amendment to Certificate of Incorporation dated March 31, 1998
         (creating Series A Junior Participating Preferred Stock)

3.2*     By-laws                                                         (D)

4.1*     Form of Common Stock Certificate, $.01 par value                (C)

10.1     Lease Agreement for Elmwood Park, New Jersey Premises,
         as in effect at October 31, 1999

10.2     Employment Agreement between the Company and
         Marc Grodman as in effect at December 31, 1999


                                    29

<PAGE>



10.3     Employment Agreement between the Company and
         Howard Dubinett as in effect at December 31, 1999

10.4     Employment Agreement between the Company and
         Sam Singer as in effect at December 31, 1999

10.5*    The Company's 1989 Stock Option Plan                            (B)

10.6*    Acquisition Agreement made as of April 9, 1998 for the          (E)
         acquisition by the Company of all of the outstanding capital
         stock of Medilabs, Inc.

10.7*    Rights  Agreement  dated as of March 31, 1998 including         (F)
         Exhibits thereto  between  the Company and  American  Stock
         Transfer & Trust Company as Rights Agent

10.8     Asset  Sale/Purchase  Agreement  made as of December 2, 1999
         for the acquisition  by the  Company  of the  WEB  Business
         of the  Medical Marketing Group, Inc.

10.9     Asset/Sale Purchase Agreement made as of December 14, 1999
         for the acquisition by the Company's wholly-owned BRLI No. 1
         Acquisition Corp. subsidiary of the Health Ford Business of
         Right Body Foods, Inc.

10.10    Employment Agreement between the Company and Rebecca
         Klafter, chief executive officer of Right Body Foods, Inc.,
         dated December 14, 1999

21       Subsidiaries of the Company

The following are the Company's two wholly-owned subsidiaries:

                                                            Name under which it
Name                      State of Incorporation             Conducts Business
- ----                      ----------------------             -----------------

Medilabs, Inc.                   New York                        Medilabs
BRLI No. 1 Acquisition Corp.    New Jersey                   Right Body Foods

      The exhibits  designated  above with an asterisk (*) have  previously been
filed  with  the  Commission  and,  pursuant  to  17  C.F.R.  Secs.  201.24  and
240.12b-32, are incorporated by reference to the documents as indicated below.

(A)   Incorporated by reference to exhibit filed with the Company's Registration
      Statement on Form S-1 (File No. 33-31360).

(B)   Incorporated  by  reference  to exhibit  filed with the  Company's  annual
      report on Form 10KSB for the year ended October 31, 1992.

(C)   Incorporated by reference to exhibit filed with the Company's Registration
      Statement on Form SB-2 (File No. 33-68678).

(D)   Incorporated by reference to exhibit filed with the Company's Registration
      Statement on Form S-18 (File No. 33-5048-NY).

(E)   Incorporated  by reference to exhibit filed with the  Company's  report on
      Form 8-K for April 22, 1998.

(F)   Incorporated  by reference to exhibit filed with the  Company's  report on
      Form 8-A dated March 31, 1998.

                                       30

<PAGE>



                                   SIGNATURES

      In accordance with Section 13 or 15(d) of the Exchange Act, the registrant
caused this report to be signed on its behalf by the undersigned, thereunto duly
authorized.

BIO-REFERENCE LABORATORIES, INC.


By:  /S/ Marc D. Grodman
- ------------------------
Marc D. Grodman
Chairman of the Board, President,
Chief Executive Officer and Director

Dated:January 31, 2000

In  accordance  with the Exchange  Act, this report has been signed below by the
following  persons on behalf of the  registrant and in the capacities and on the
dates indicated.

/S/ Marc D. Grodman
- ------------------------
Marc D. Grodman
Chairman of the Board, President,
Chief Executive Officer and Director
January 31, 2000

/S/ Howard Dubinett
- ------------------------
Howard Dubinett
Executive Vice President,
Chief Operating Officer and Director
January 31, 2000

/S/ Sam Singer
- ------------------------
Sam Singer
Vice President, Chief Financial Officer,
Chief Accounting Officer and Director
January 31, 2000

/S/ Frank DeVito
- ------------------------
Frank DeVito
Director
January 31, 2000

/S/ John Roglieri
- ------------------------
John Roglieri
Director
January 31, 2000

/S/ Gary Lederman
- ------------------------
Gary Lederman
Director
January 31, 2000






                                       31

<PAGE>



                          INDEPENDENT AUDITOR'S REPORT

To the Board of Directors and Stockholders of
  Bio-Reference Laboratories, Inc.
  Elmwood Park, New Jersey



            We have  audited the  accompanying  consolidated  balance  sheets of
Bio-Reference  Laboratories,  Inc. and its subsidiary as of October 31, 1999 and
1998,  and the related  consolidated  statements  of  operations,  shareholders'
equity,  and cash flows for each of the three  fiscal  years in the period ended
October 31, 1999. These consolidated financial statements are the responsibility
of the  Company's  management.  Our  responsibility  is to express an opinion on
these consolidated financial statements based on our audits.

            We  conducted  our  audits in  accordance  with  generally  accepted
auditing  standards.  Those standards require that we plan and perform the audit
to  obtain  reasonable  assurance  about  whether  the  consolidated   financial
statements are free of material misstatement.  An audit includes examining, on a
test basis,  evidence supporting the amounts and disclosures in the consolidated
financial statements. An audit also includes assessing the accounting principles
used and  significant  estimates made by  management,  as well as evaluating the
overall  consolidated  financial  statement  presentation.  We believe  that our
audits provide a reasonable basis for our opinion.

            In our opinion,  the consolidated  financial  statements referred to
above present  fairly,  in all material  respects,  the  consolidated  financial
position of  Bio-Reference  Laboratories,  Inc. and its subsidiary as of October
31, 1999 and 1998, and the  consolidated  results of their  operations and their
cash flows for each of the three fiscal  years in the period  ended  October 31,
1999, in conformity with generally accepted accounting principles.








                                          MOORE STEPHENS, P. C.
                                          Certified Public Accountants.

Cranford, New Jersey
January 7, 2000
[Except for Note 22B as to
which the date is January 26, 2000
and Note 22C as to which the date
is January 19, 2000]

                                       F-1

<PAGE>





BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED BALANCE SHEETS
- ------------------------------------------------------------------------------


                                                               October 31,
                                                               -----------
                                                          1 9 9 9       1 9 9 8
                                                          -------       -------
Assets:
Current Assets:
  Cash and Cash Equivalents                           $  2,128,474   $ 2,784,147
  Accounts Receivable - Net                             18,615,496    20,749,696
  Inventory                                                572,279       587,101
  Certificates of Deposit - Restricted                          --     3,646,250
  Other Current Assets                                     404,124     1,100,867
  Deferred Tax Asset                                            --       344,000
                                                      ------------   -----------

  Total Current Assets                                  21,720,373    29,212,061
                                                      ------------   -----------

Property and Equipment:
  Automobiles                                               41,740        41,740
  Medical Equipment                                      3,466,574     3,263,101
  Leasehold Improvements                                 1,152,599       429,993
  Furniture and Fixtures                                   550,554       508,630
                                                      ------------   -----------

  Totals - At Cost                                       5,211,467     4,243,464
  Less:  Accumulated Depreciation                        3,039,128     2,022,928
                                                      ------------   -----------

  Property and Equipment - Net                           2,172,339     2,220,536
                                                      ------------   -----------

Other:
  Certificate of Deposit - Restricted                           --        33,750
  Due from Related Party                                   138,518       187,118
  Deposits                                                 278,619       303,354
  Goodwill                                               5,396,863     5,746,601
  Intangible Assets                                      1,764,740     2,507,149
  Other Assets                                             846,546       567,769
                                                      ------------   -----------

  Total Other                                            8,425,286     9,345,741
                                                      ------------   -----------

  Total Assets                                        $ 32,317,998   $40,778,338
                                                      ============   ===========




The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                        F-2

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED BALANCE SHEETS
- ------------------------------------------------------------------------------

<TABLE>

                                                                      October 31,
                                                                      -----------
                                                                 1 9 9 9       1 9 9 8
                                                                 -------       -------

Liabilities and Shareholders' Equity:
Current Liabilities:
<S>                                                         <C>            <C>
  Accounts Payable                                          $  5,540,787   $ 4,379,961
  Accrued Salaries and Commissions                             1,349,175     1,367,785
  Accrued Expenses                                               849,463       625,814
  Current Maturities of Long-Term Debt [Net of Discount]       1,215,671     2,071,058
  Notes Payable - Banks                                        8,700,905    12,000,000
  Capitalized Lease Obligation - Short-Term Portion              308,251       229,232
  Taxes Payable                                                  304,098       173,962
                                                            ------------   -----------

  Total Current Liabilities                                   18,268,350    20,847,812
                                                            ------------   -----------

Long-Term Liabilities:
  Long-Term Debt Less Current Maturities                       2,000,000     3,306,617
  Capitalized Lease Obligations - Long-Term Portion              680,538       400,975
                                                            ------------   -----------

  Total Long-Term Liabilities                                  2,680,538     3,707,592
                                                            ------------   -----------

Commitments and Contingencies                                         --            --
                                                            ------------   -----------

Shareholders' Equity:
  Preferred Stock, Par Value $.10  Per Share,
   Authorized 1,062,589 Shares; None Issued                           --            --

  Series A - Senior Preferred Stock, Par Value $.10 Per
   Share, Authorized, Issued and Outstanding 604,078 Shares        60,408        60,408

  Series A - Junior Participating Preferred Stock, Par Value
   $.10 Per Share, Authorized 3,000 Shares; None Issued               --            --

  Common Stock, Par Value $.01 Per Share, Authorized
   18,333,333 Shares; Issued and Outstanding 7,700,777 and
   7,212,910 Shares at October 31, 1999 and 1998,
   Respectively                                                   77,008        72,129

  Additional Paid-in Capital                                  23,294,673    22,998,015

  Accumulated [Deficit]                                      (11,613,433)   (6,634,985)
                                                            ------------   -----------

  Totals                                                      11,818,656    16,495,567
  Deferred Compensation                                         (449,546)     (272,633)
                                                            ------------   -----------

  Total Shareholders' Equity                                  11,369,110    16,222,934
                                                            ------------   -----------

  Total Liabilities and Shareholders' Equity                $ 32,317,998   $40,778,338
                                                            ============   ===========
</TABLE>


The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                          F-3

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED STATEMENTS OF OPERATIONS
- ------------------------------------------------------------------------------

<TABLE>

                                                        Y e a r s   e n d e d
                                             -----------------------------------------
                                                         O c t o b e r   3 1,
                                             -----------------------------------------
                                                 1 9 9 9       1 9 9 8       1 9 9 7
                                                 -------       -------       -------


<S>                                          <C>            <C>            <C>
Net Revenues                                 $ 53,856,414   $ 46,553,730   $38,660,184
                                             ------------   ------------   -----------

Cost of Services:
  Depreciation and Amortization                   856,668        704,293      390,953
  Employee Related Expenses                    14,096,914     11,675,839    8,595,078
  Reagents and Laboratory Supplies              6,974,857      5,567,394    4,777,325
  Other Cost of Services                        8,921,898      7,110,482    5,575,918
                                             ------------   ------------   ----------

  Total Cost of Services                       30,850,337     25,058,008   19,339,274
                                             ------------   ------------   ----------

  Gross Profit                                 23,006,077     21,495,722   19,320,910
                                             ------------   ------------   ----------

General and Administrative Expenses:
  Depreciation and Amortization                   974,529        935,370      798,365
  Other General and Administrative Expenses    15,677,788     13,410,446   11,346,007
  Provision for Doubtful Accounts               6,855,221      6,084,941    5,291,507
  Expenses of Impaired Assets                   2,924,371             --           --
                                             ------------   ------------   ----------

  Total General and Administrative Expenses    26,431,909     20,430,757   17,435,879
                                             ------------   ------------   ----------

  [Loss] Income from Operations                (3,425,832)     1,064,965    1,885,031
                                             ------------   ------------   ----------

Non-Recurring Gain on Sale of Intangible
  Assets                                               --        333,900    2,025,689
                                             ------------   ------------   ----------

Other [Income] Expense:
  Interest Expense                              1,465,765      1,280,737    1,124,432
  Interest Income                                (265,069)      (440,155)    (274,887)
  Other Income                                    (15,380)            --           --
                                             ------------   ------------   ----------

  Total Other Expense - Net                     1,185,316        840,582      849,545
                                             ------------   ------------   ----------

  [Loss] Income Before Income Taxes            (4,611,148)       558,283    3,061,175

Provision for Income Tax Expense [Benefit]        367,300        (38,300)    (138,740)
                                             ------------   ------------   ----------

  Net [Loss] Income                          $ (4,978,448)  $    596,583   $3,199,915
                                             ============   ============   ==========

  Net [Loss] Income Per Share                $       (.68)  $        .08   $      .48
                                             ============   ============   ==========

  Net [Loss] Income Per Share - Assuming
   Dilution                                  $       (.68)  $        .07   $      .43
                                             ============   ============   ==========

</TABLE>




The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                          F-4

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY
- ------------------------------------------------------------------------------
<TABLE>


                                            Series A                            Additional                            Total
                                    Senior Preferred Stock  Common Stock         Paid-in  Accumulated   Deferred  Shareholders'
                                       Shares   Amount    Shares    Amount       Capital    [Deficit]Compensation    Equity

<S>                                   <C>      <C>       <C>        <C>       <C>         <C>           <C>        <C>
  Balance - October 31, 1996          604,078  $60,408   6,300,280  $63,003   $22,433,297 $(10,431,483) $ (22,217) $12,103,008

Shares Issued for Deferred Compensation    --       --     815,000    8,150      337,919            --   (346,069)          --

Warrants Issued for Deferred Compensation  --       --          --       --       13,423            --    (13,423)          --

Shares Issued in Connection with an
  Acquisition Agreement                    --       --      54,096      541      127,320            --         --      127,861

Shares Released from Escrow                --       --          --       --       55,201            --         --       55,201

Amortization of Deferred Compensation      --       --          --       --           --            --     38,658       38,658

Net Income for the Year                    --       --          --       --           --     3,199,915         --    3,199,915
                                     --------  -------   ---------  -------   ----------  ------------  ---------  -----------

  Balance - October 31, 1997          604,078   60,408   7,169,376   71,694   22,967,160    (7,231,568)  (343,051)  15,524,643

Amortization of Deferred Compensation      --       --          --       --           --            --     70,418       70,418

Shares Issued on Exercise of Warrants      --       --      43,534      435       30,855            --         --       31,290

Net Income for the Year                    --       --          --       --           --       596,583         --      596,583
                                     --------  -------   ---------  -------   ----------  ------------  ---------  -----------

  Balance - October 31, 1998          604,078   60,408   7,212,910   72,129   22,998,015    (6,634,985)  (272,633)  16,222,934

Shares Issued in Lieu of Compensation      --       --      25,000      250       25,688            --         --       25,938

Shares Issued for Deferred Compensation    --       --     490,000    4,900      270,970            --   (275,870)          --

Escrow Shares Cancelled                    --       --     (27,133)    (271)          --            --         --         (271)

Amortization of Deferred Compensation      --       --          --       --           --            --     98,957       98,957

Net [Loss] for the Year                    --       --          --       --           --    (4,978,448)        --   (4,978,448)
                                     --------  -------   ---------  -------   ----------  ------------  ---------  -----------

  Balance - October 31, 1999          604,078  $60,408   7,700,777  $77,008   $23,294,673 $(11,613,433) $(449,546) $11,369,110
                                     ========  =======   =========  =======   =========== ============  =========  ===========
</TABLE>


The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                              F-5

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED STATEMENTS OF CASH FLOWS
- ------------------------------------------------------------------------------


<TABLE>

                                                              Y e a r s   e n d e d
                                                               O c t o b e r   3 1,
                                                       1 9 9 9       1 9 9 8       1 9 9 7
                                                       -------       -------       -------

Operating Activities:
<S>                                                <C>            <C>            <C>
  Net [Loss] Income                                $ (4,978,448)  $    596,583   $3,199,915
                                                   ------------   ------------   ----------
  Adjustments  to Reconcile Net [Loss] Income to
   Net Cash Provided by [Used for]
   Operating Activities:
   Depreciation and Amortization                      1,831,197      1,639,663    1,189,318
   Amortization of Deferred Compensation                 98,957         70,418       38,658
   Amortization of Deferred Interest                     92,000         53,667           --
   Amortization Reversal Due to Legal Settlement             --        (56,859)          --
   Expenses of Impaired Assets                        2,924,371             --           --
   Provision for Doubtful Accounts                    6,855,221      6,084,941    5,291,507
   Other                                                 25,667             --           --
   Nonrecurring Gain on Sale of Intangible Assets            --       (333,900)  (2,025,689)
   Deferred Income Taxes                                344,000        (86,000)    (258,000)

  Changes in Assets and Liabilities
   [Net of Effects from Acquisitions]:
   [Increase] Decrease in:
     Accounts Receivable                             (6,721,021)   (10,990,642)  (7,509,627)
     Other Assets                                      (278,777)      (120,866)    (105,866)
     Inventory                                           14,822        117,625      (59,493)
     Other Current Assets                               696,743        636,478      142,504

   Increase [Decrease] in:
     Accounts Payable and Accrued Expenses              740,865       (642,123)    (210,861)
     Taxes Payable                                      130,136       (196,586)     136,030
                                                   ------------   ------------   ----------

   Total Adjustments                                  6,754,181     (3,824,184)  (3,371,519)
                                                   ------------   ------------   ----------

  Net Cash - Operating Activities - Forward           1,775,733     (3,227,601)    (171,604)
                                                   ------------   ------------   ----------

Investing Activities:
  Acquisition of Property and Equipment                (392,102)      (194,558)    (143,613)
  Purchase of Certificate of Deposit - Restricted            --     (3,680,000)  (3,680,000)
  Maturities of Certificate of Deposit - Restricted   3,680,000      3,680,000    3,680,000
  Cash Paid for Medilabs, Inc. Acquisition                   --     (4,000,000)          --
  Cash Acquired During Acquisition                           --         86,412           --
  Reduction [Additions] of Deposits                      24,735         (3,985)       6,907
  Repayment of Related Party Receivable                  48,600         27,000       20,800
  Payment for Acquisition of Intangible Assets               --       (152,867)     (44,375)
  Proceeds from Sale of Intangible Assets                    --             --    4,600,000
                                                   ------------   ------------   ----------

  Net Cash - Investing Activities - Forward        $  3,361,233   $ (4,237,998)  $4,439,719

</TABLE>

The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                             F-6

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


CONSOLIDATED STATEMENTS OF CASH FLOWS
- ------------------------------------------------------------------------------

<TABLE>
                                                              Y e a r s   e n d e d
                                                               O c t o b e r   3 1,
                                                       1 9 9 9       1 9 9 8       1 9 9 7
                                                       -------       -------       -------

<S>                                                <C>            <C>            <C>
  Net Cash - Operating Activities - Forwarded      $  1,775,733   $ (3,227,601)  $ (171,604)
                                                   ------------   ------------   ----------

  Net Cash - Investing Activities - Forwarded         3,361,233     (4,237,998)  $4,439,719
                                                   ------------   ------------   ----------

Financing Activities:
  Proceeds from Long-Term Debt                               --      4,000,000           --
  Payments of Long-Term Debt                         (2,254,004)    (1,001,368)    (739,895)
  Payments of Capital Lease Obligations                (239,540)      (178,954)    (216,448)
  Payments of Subordinated Notes Payable                     --         (1,339)    (234,390)
  [Decrease] Increase in Revolving Line of Credit    (3,299,095)     4,386,292   (2,317,031)
  Decrease in Restricted Cash                                --        852,000           --
  Proceeds from Exercise of Warrants                         --         31,290           --
                                                   ------------   ------------   ----------

  Net Cash - Financing Activities                    (5,792,639)     8,087,921   (3,507,764)
                                                   ------------   ------------   ----------

  Net [Decrease] Increase in Cash and Cash
   Equivalents                                         (655,673)       622,322      760,351

Cash and Cash Equivalents - Beginning of Years        2,784,147      2,161,825    1,401,474
                                                   ------------   ------------   ----------

   Cash and Cash Equivalents - End of Years        $  2,128,474   $  2,784,147   $2,161,825
                                                   ============   ============   ==========

  Supplemental Disclosures of Cash Flow Information:
   Cash paid during the years for:
     Interest                                      $  1,437,602   $  1,179,533   $1,118,540
     Income Taxes                                  $     33,736   $    120,407   $   44,136
</TABLE>

Supplemental Schedule of Non-Cash Investing and Financing Activities:
  During 1997,  the Company  incurred  four capital lease  obligations  totaling
$252,279 in connection with the acquisition of medical equipment.

  In  fiscal  1997,  the  Company  issued  debt in the  amount  of  $108,000  in
connection with the acquisition of a customer list related to a 1994 agreement.

  During 1998,  the Company  incurred  two capital  lease  obligations  totaling
$93,143 in connection with the acquisition of medical equipment.

  During 1999,  the Company  incurred seven capital lease  obligations  totaling
$598,122 in connection with the  acquisition of medical  equipment and leasehold
improvements.

  In May 1999, the Company  recorded  $625,000 in intangible  assets and accrued
expenses related to an employment agreement.

[See Notes 7, 13, 16 and 22] for additional non-cash transactions]


The  Accompanying  Notes are an Integral  Part of These  Consolidated  Financial
Statements.

                                             F-7

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
- ------------------------------------------------------------------------------



[1] Organization and Business

Bio-Reference  Laboratories,  Inc.  was  incorporated  on  December  21, 1981 to
initially  engage in the business of developing  and marketing  on-site  medical
screening  examinations.  Since February 1987, its emphasis has been in clinical
laboratory  operations,  principally servicing the greater New York metropolitan
area  and  providing   specialty   services   throughout   the  United   States.
Bio-Reference Laboratories, Inc. and its wholly-owned subsidiary [the "Company"]
markets  its  clinical  laboratory  testing  services  directly  to  physicians,
hospitals, clinics, and other health facilities.

[2] Summary of Significant Accounting Policies

Principles of Consolidation - The consolidated  financial statements include the
accounts  of the  Company  and  its  wholly-owned  subsidiary.  All  significant
intercompany  accounts and transactions have been eliminated.  The operations of
GenCare Biomedical Research  Corporation are included in operations from January
1, 1995 through  September  30, 1997 [See Note 20]. The  operations of Medilabs,
Inc. are included in operations commencing April 9, 1998 [See Note 16].

Revenue  Recognition  - Revenues  are  recognized  at the time the  services are
performed. Revenues on the statements of operations are as follows:
                                                    Y e a r s  e n d e d
                                           ----------------------------------
                                                     O c t o b e r  3 1,
                                           ----------------------------------
                                             1 9 9 9     1 9 9 8     1 9 9 7
                                             -------     -------     -------

Gross Revenues                            $125,958,897 $102,351,588 $80,462,096
                                          ------------ ------------ -----------
Contractual Adjustments and Discounts:
  Medicare/Medicaid Portion                 38,779,145   33,064,535  23,090,659
  Other                                     33,323,338   22,733,323  18,711,253
                                          ------------ ------------  ----------

  Total Contractual Adjustments and
   Discounts                                72,102,483   55,797,858  41,801,912
                                          ------------ ------------  ----------

  Net Revenues                            $ 53,856,414 $ 46,553,730 $38,660,184
  ------------                            ============ ============ ===========

Contractual  Credits and  Provision  for Doubtful  Accounts - An  allowance  for
contractual  credits  is  determined  based  upon a review of the  reimbursement
policies and subsequent  collections for the different types of receivables.  An
allowance for doubtful  accounts is determined  based upon a percentage of total
receivables.  The  aggregate  allowance,  which is shown  net  against  accounts
receivable, was $15,312,935,  $13,494,475 and $8,564,436 as of October 31, 1999,
1998 and 1997, respectively.

Inventory - Inventory  is stated at the lower of cost [on a first-in,  first-out
basis] or market. Inventory consists primarily of clinical supplies.

Stock Options Issued to Employees - The Company  adopted  Statement of Financial
Accounting  Standards No. 123,  "Accounting for Stock-Based  Compensation,"  for
financial note  disclosure  purposes and continues to apply the intrinsic  value
method of Accounting  Principles  Board ["APB"] Opinion No. 25,  "Accounting for
Stock Issued to Employees," for financial reporting purposes.

Deferred  Income Taxes - Deferred income tax assets and liabilities are computed
annually for differences between the financial statement and tax bases of assets
and liabilities that will result in taxable or deductible  amounts in the future
based on  enacted  tax laws and rates  applicable  to the  periods  in which the
differences are expected to affect taxable income.

                                       F-8

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #2
- ------------------------------------------------------------------------------



[2] Summary of Significant Accounting Policies [Continued]

Deferred Income Taxes  [Continued] - Valuation  allowances are established  when
necessary to reduce  deferred tax assets to the amount  expected to be realized.
Income tax expense is the tax payable or refundable for the period plus or minus
the change during the period in deferred tax assets and liabilities.

Net Income Per Share - Basic EPS is based on average  common shares  outstanding
and diluted EPS includes the effects of potential common stock, such as, options
and warrants, if dilutive.  Securities that could potentially dilute earnings in
the future are listed in Notes 9 and 22.

Impairment  - Certain  long-term  assets of the Company  including  goodwill are
reviewed  at least  annually  as to  whether  their  carrying  value has  become
impaired,  pursuant to guidance established in Statement of Financial Accounting
Standards ["SFAS"] No. 121,  "Accounting for the Impairment of Long-Lived Assets
and for Long-Lived Assets to be Disposed Of." Management  considers assets to be
impaired if the  carrying  value  exceeds the future  projected  cash flows from
related operations [undiscounted and without interest charges]. If impairment is
deemed to exist, the assets will be written down to fair value.  Management also
re-evaluates the periods of amortization to determine whether  subsequent events
and  circumstances  warrant revised  estimates of useful lives.  During the year
ended October 31, 1999,  an impairment of $2,924,371  was recorded in connection
with assets  acquired  for the  hemo-dialysis  business.  The  breakdown of this
expense was an increase in the  allowance  for related  accounts  receivable  of
approximately  $2,000,000  and the  write  down  of  goodwill  of  approximately
$900,000  as  a  result  of   management's   intent  to  no  longer  pursue  the
hemo-dialysis  business.  Accordingly,  the Company has made revisions to future
endeavors in this area.

Property  and   Equipment  -  Property  and   equipment  are  carried  at  cost.
Depreciation is computed by the  straight-line  method over the estimated useful
lives  of the  respective  assets  which  range  from 2 to 15  years.  Leasehold
improvements  are amortized over the life of the lease,  which is  approximately
five years.

The statements of operations  reflect  depreciation  expense related to property
and equipment of  $1,038,421,  $820,226 and $419,462 for the years ended October
31, 1999, 1998 and 1997, respectively.

On sale or retirement,  the asset cost and related  accumulated  depreciation or
amortization  are removed  from the  accounts,  and any related  gain or loss is
reflected  in income.  Repairs  and  maintenance  are  charged  to expense  when
incurred.

Use of Estimates - The  preparation of financial  statements in conformity  with
generally accepted  accounting  principles requires management to make estimates
and assumptions  that affect the reported  amounts of assets and liabilities and
disclosure of  contingent  assets and  liabilities  at the date of the financial
statements  and the  reported  amounts  of  revenues  and  expenses  during  the
reporting period. Actual results could differ from those estimates.

Goodwill - Goodwill represents the excess of the cost of companies acquired over
the fair  value of  their  net  assets  at  dates  of  acquisition  and is being
amortized  on  the  straight-line  method  over  20  years.  The  statements  of
operations reflect  amortization expense related to goodwill for the years ended
October  31,  1999,   1998  and  1997  of  $349,738,   $254,022  and   $203,490,
respectively.  The balance sheet reflects accumulated amortization of $1,597,767
and $1,248,029 as of October 31, 1999 and 1998, respectively.

Intangible  Assets - Intangible  assets are  amortized  using the  straight-line
method.  The statements of operations  reflect  amortization  expense related to
intangible assets of $443,038, $565,415 and $566,366 for the years ended October
31, 1999, 1998 and 1997,  respectively.  The balance sheet reflects  accumulated
amortization  of  $2,271,436  and  $2,173,034  as of October  31, 1999 and 1998,
respectively.


                                       F-9

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #3
- ------------------------------------------------------------------------------


[2] Summary of Significant Accounting Policies [Continued]

Intangible Assets [Continued] - A summary is as follows:
                                                 Accumulated Net of Accumulated
                                                 Amortization  Amortization
                                                  October 31,   October 31,
   Intangible Asset     Life in Years   Cost       1 9 9 9       1 9 9 9
   ----------------     -------------   ----       -------       -------

Customer Lists                 20   $ 1,449,202  $   578,736  $   870,466
Covenants Not-to-Compete  3 - 7.5     1,020,000      977,574       42,426
Employment Agreement        5 - 7     1,025,000      444,643      580,357
Costs Related to
 Acquisitions              1 - 20       385,969      245,426      140,543
Patent                         17       156,005       25,057      130,948
                                    -----------  -----------  -----------

  Totals                            $ 4,036,176  $ 2,271,436  $ 1,764,740
  ------                            ===========  ===========  ===========

                                                 Accumulated Net of Accumulated
                                                 Amortization  Amortization
                                                  October 31,   October 31,
   Intangible Asset     Life in Years   Cost       1 9 9 8       1 9 9 8
   ----------------     -------------   ----       -------       -------

Customer Lists                 20   $ 2,469,202 $   620,143    $ 1,849,059
Covenants Not-to-Compete  3 - 7.5     1,200,000     965,279        234,721
Employment Agreement            5       400,000     366,669         33,331
Costs Related to
 Acquisitions              1 - 20       454,976     205,260        249,716
Patent                         17       156,005      15,683        140,322
                                    ----------- -----------    -----------

  Totals                            $ 4,680,183 $ 2,173,034    $ 2,507,149
  ------                            =========== ===========    ===========

Advertising  Costs  -Advertising  costs are expensed when incurred.  Advertising
costs amounted to  approximately  $548,000,  $819,000 and,  $467,000 and for the
years ended October 31, 1999, 1998 and 1997, respectively.

Cash and Cash  Equivalents - Cash  equivalents  are comprised of certain  highly
liquid  investments with a maturity of three months or less when purchased.  The
Company had $1,113,418  and  $1,843,186 in cash  equivalents at October 31, 1999
and 1998, respectively.

[3] Note Payables - Banks

In April 1998,  the Company  amended its revolving loan agreement with PNC Bank.
The maximum  amount of the credit line available to the Company is the lesser of
(i) $14,000,000 or (ii) 50% of the Company's  qualified accounts  receivable [as
defined in the agreement]  plus the face amount of any  certificates  of deposit
pledged  as  collateral  for this  loan  minus  the  amount  of the  outstanding
principal  balance of any term loans with the same bank.  Interest  on  advances
which are  collateralized  by  certificates  of deposit  will be at 2% above the
certificate  of deposit  interest  rate.  Interest on other  advances will be at
prime plus 1.25%.  The certificate of deposit interest rate was 5% through March
25,  1999.  The  credit  line  is  collateralized  by  substantially  all of the
Company's assets and the assignment of a $4,000,000 life insurance policy on the
president of the Company. The line of credit is available through March 2001 and
may be extended for annual periods by mutual consent,  thereafter.  The terms of
this agreement  contain,  among other  provisions,  requirements for maintaining
defined levels of capital  expenditures and net worth,  various financial ratios
and  insurance  coverage.  As of October 31,  1999 and 1998,  the Company was in
default of certain covenants,  however, the Company  subsequently  received bank
waivers for these  defaults [See Note 22B]. As of October 31, 1998,  the Company
utilized  $12,000,000  of this  credit  facility.  As of October 31,  1999,  the
Company utilized $8,700,905 of this credit facility.

Prime rate at October 31, 1999 and 1998 was 8.25% and 8.0%, respectively.

The weighted  average interest rate on short-term  borrowings  outstanding as of
October 31, 1999 and 1998 was 9.22% and 8.75%, respectively.

                                      F-10

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #4
- ------------------------------------------------------------------------------




[4] Long-Term Debt
                                                               October 31,
                                                               -----------
                                                           1 9 9 9    1 9 9 8
                                                           -------    -------

[A]  Note Payable to LTC Service and Holdings, Inc.
     Due April 2000. Interest imputed at 11.6%,
     unsecured.                                          $  415,671 $ 1,323,667

[B]  Notes Payable to PNC Bank.  Due April 2002.
     Interest at prime plus 2% for the unsecured portion
     and prime plus 1.6% for the secured portion.         2,800,000   3,600,000

     Note Payable to PNC Bank.  Due October 1999.
     Interest at prime plus 1.00%.                               --      86,424

     Notes Payable to PNC Bank.  Due July 2000.
     Interest at prime plus 1.00% and certificate of
     deposit rate plus 2%.                                       --     315,259

     Other                                                       --      52,325
                                                         ---------- -----------

Totals                                                    3,215,671   5,377,675
Less:  Current Maturities                                 1,215,671   2,071,058
                                                         ---------- -----------

  Long-Term Debt                                         $2,000,000 $ 3,306,617
  --------------                                         ========== ===========

[A] On April 9, 1998, the Company acquired the assets and certain liabilities of
Medilabs,  Inc. from LTC Service and Holdings, Inc. The purchase price consisted
of $4,000,000 cash plus a $1,500,000 promissory note payable without interest in
three semi-annual  installments commencing April 1999. Interest was imputed at a
rate of 11.6% on this note.

[B] In April 1998,  the Company  entered into an agreement to borrow  $4,000,000
from PNC Bank.  The note is payable in  forty-seven  principal  installments  of
$66,667  commencing  May 1, 1998 and one final  balloon  payment.  The unsecured
portion of $2,000,000  bears interest at an annual rate of 10.25% to 10.5%.  The
secured  portion of  $2,000,000  bears  interest  at an annual  rate of 9.85% to
10.10%.  This  note  is in  accordance  with  the  provisions  of the  Company's
revolving loan agreement [See Note 3] with the same lender.

Maturities  of debt at  October  31,  1999 in each of the next five years are as
follows:

2000                                $ 1,215,671
2001                                    800,000
2002                                  1,200,000
2003                                         --
2004                                         --
                                    -----------

  Total                             $ 3,215,671
  -----                             ===========

[5] Related Party Transactions

On October 1, 1989,  an unsecured  promissory  note was  received  from Dr. Marc
Grodman ["Dr. Grodman"],  president of the Company, in exchange for a receivable
in the  amount of  $235,354.  As of  October  31,  1999 and 1998,  $138,518  and
$187,118 was remaining on the note. This note is non-interest bearing and has no
fixed terms.



                                      F-11

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #5
- ------------------------------------------------------------------------------


[6] Income Taxes

The reconciliation of income tax from continuing operations computed at the U.S.
federal  statutory  tax rate to the  Company's  effective  income tax rate is as
follows:

                                                           October 31,
                                                  -----------------------------
                                                  1 9 9 9   1 9 9 8   1 9 9 7
                                                  -------   -------   -------

U.S. Federal Statutory Rate                        (34.0)%    34.0 %     34.0%
State and Local Income Taxes, Net of U.S.
  Federal Income Tax Benefit                          -- %     9.0 %     10.0%
Other                                                 -- %   (11.1)%     (7.5)%
Utilization of Net Operating Loss Carryforwards       -- %   (38.8)%    (41.0)%
Change in Valuation Allowance                       42.0 %      --%        -- %
                                                  ------    ------    -------

  Actual Rate                                        8.0 %    (6.9)%     (4.5)%
  -----------                                     ======    ======    =======

The  provision  for  income  taxes  shown  in  the  consolidated  statements  of
operations consist of the following:
                                                      October 31,
                                          -------------------------------------
                                              1 9 9 9     1 9 9 8     1 9 9 7
                                              -------     -------     -------
Current:
  Federal                                $       --    $   16,200  $   79,947
  State and Local                            23,300        31,500      39,313

Deferred:
  Federal                                   272,000[1]    (68,000)   (204,000)
  State and Local                            72,000[1]    (18,000)    (54,000)
                                         ----------    ----------  ----------

  Total Provision for Income Taxes       $  367,300    $  (38,300) $ (138,740)
  --------------------------------       ==========    ==========  ==========

[1] Increase in deferred tax valuation allowance.

For the year ended October 31, 1998, the Company utilized approximately $500,000
of net operating loss carryforwards  which resulted in a tax benefit for federal
and state  purposes of  approximately  $200,000.  For the year ended October 31,
1997,  the Company  utilized  approximately  $3,600,000  of net  operating  loss
carryforwards  which resulted in a tax benefit for federal and state purposes of
approximately $1,450,000.

At October 31,  1999,  the  Company  had net  operating  loss  carryforwards  of
approximately  $9,345,000 for federal income tax purposes, which expire in years
2006 through 2014. In addition,  the Company had net operating  losses for state
purposes. The Company operates in several states,  however, most of its business
is conducted in the New Jersey and New York area.  The following  summarizes the
operating loss carryforwards by year of expiration:

                                  Federal     New Jersey     New York
Expiration Date                   Amount        Amount        Amount

   2000                         $       --   $ 2,375,000   $       --
   2006                            825,000            --      383,000
   2007                          1,255,000            --    1,253,000
   2008                          2,375,000            --    2,373,000
   2009                            390,000            --           --
   2014                          4,500,000     4,500,000    4,500,000
                                ----------   -----------   ----------

   Total                        $9,345,000   $ 6,875,000   $8,509,000
   -----                        ==========   ===========   ==========

                                      F-12

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #6
- ------------------------------------------------------------------------------


[6] Income Taxes [Continued]

At October  31,  1998,  the Company  had a deferred  tax asset of  approximately
$2,000,000 and a valuation allowance of approximately  $1,656,000 related to the
asset,  a decrease of $286,000  since  October 31, 1997.  The deferred tax asset
primarily relates to net operating loss carryforwards.

At October  31,  1999,  the Company  had a deferred  tax asset of  approximately
$4,000,000 and a valuation allowance of approximately  $4,000,000 related to the
asset, an increase of $2,344,000  since October 31, 1998. The deferred tax asset
primarily relates to net operating loss carryforwards.

[7] Capital Transactions

[A]  Preferred  Stock and Common Stock - The Company is  authorized  to issue an
aggregate of 1,669,667 shares of preferred  stock,  $.10 par value. On April 20,
1993, in order to facilitate the Company's 1993 proposed  public  offering,  Dr.
Grodman  canceled his pro-rata option  contained in his employment  contract and
all other  outstanding  options and warrants to purchase  shares of Common Stock
held by Dr.  Grodman,  his wife and an affiliated  entity (the "Grodman  Group")
exercisable  to purchase an aggregate  604,078  shares of Common Stock at prices
ranging  from  $1.4438  to $1.50 or an  average  price of $1.47  per  share,  in
consideration  for the issuance to the Grodman Group of 604,078  shares of a new
class of senior  preferred  stock,  $.10 par value per share ("Senior  Preferred
Stock").  Each share of Senior  Preferred  Stock had the same voting rights (one
vote per share),  dividend rights and liquidation rights as each share of Common
Stock and for a period of 10 years  after  issuance,  was  convertible  into one
share of Common Stock upon payment of a conversion price of $1.50 per share. The
604,078  shares of Senior  Preferred  Stock were issued to the Grodman  Group on
August 23, 1993.  On May 13, 1997,  pursuant to a  recapitalization,  the Senior
Preferred  Stock  was  retired  in  exchange  for a new class of Series A Senior
Preferred Stock issued to the Grodman Group.  The new Series A Senior  Preferred
Stock is  convertible  into an  aggregate  604,078  shares of Common Stock on or
before  May 1,  2007 at a  conversion  price of $.75 per  share and has the same
voting rights [one vote per share],  dividend rights and  liquidation  rights as
each share of Common Stock.

Holders of the  Company's  Common  Stock are  entitled  to one vote per share on
matters  submitted for  shareholder  vote.  Holders are also entitled to receive
dividends  ratably,  if declared.  In the event of dissolution  or  liquidation,
holders are entitled to share ratably in all assets  remaining  after payment of
liabilities.

On March 31, 1998, the Company's Board of Directors adopted a Shareholder Rights
Plan and  declared a  dividend  distribution  of one Right for each  outstanding
share of Common Stock and each  outstanding  share of Series A Senior  Preferred
Stock.   Each  Right  entitles  the  registered  holder  to  purchase  one  one-
ten-thousandth of a share of Series A Junior Participating  Preferred Stock [the
"Junior Preferred  Stock"] from the Company at a price of $4.00.  Because of the
nature of the dividend,  liquidation  and voting rights of the Junior  Preferred
Stock, the value of each one-ten-thousandth of a share of Junior Preferred Stock
is  intended  to  approximate  the value of one share of  Common  Stock.  Junior
Preferred Stock  purchasable upon exercise of the Rights will not be redeemable.
Each  outstanding  share of Junior Preferred Stock will be entitled to a minimum
preferential  quarterly  dividend  of $.05 per share and will be  entitled to an
aggregate  dividend of 10,000  times the  dividend  declared per share of Common
Stock.  In the event of liquidation,  the holders of the Junior  Preferred Stock
will be entitled to a minimum  preferential  liquidation  payment of $10,000 per
share and will be entitled to an  aggregate  payment of 10,000 times the payment
made per share of Common Stock.  Each share of Junior  Preferred Stock will have
10,000  votes,  voting  together  with the Common  Stock and the Series A Senior
Preferred Stock. In the event of any merger,  consolidation or other transaction
in which the Common Stock is  exchanged,  each share of Junior  Preferred  Stock
will be entitled to receive 10,000 times the amount received per share of Common
Stock.  The Rights are  protected by  customary  anti-dilution  provisions.  The
Rights are not  exercisable  unless any one of certain  triggering  events occur
including the acquisition by an individual or entity and their associates of 25%
or more of the outstanding  shares of Common Stock. The Shareholder  Rights Plan
is designed to protect the Company and its  shareholders  from coercive,  unfair
and inadequate  takeover bids and practices.  The Plan is designed to strengthen
the Board of  Directors'  ability to deter a person or group from  attempting to
gain control of the Company without offering a fair price and equal treatment to
all shareholders.

                                      F-13

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #7
- ------------------------------------------------------------------------------



[7] Capital Transactions [Continued]

[B] Equity  Transactions  for Services - In May 1997, the Company issued 815,000
shares of common stock and warrants to purchase  58,534  shares of the Company's
common stock at a price of $.71875 in connection  with employment and consulting
agreements and a two year extension on a loan agreement. Included in the 815,000
shares issued were 740,000 shares to three  officers of the Company.  The shares
are  forfeitable  in part in various  amounts if the  employee's  employment  is
terminated  "for cause" or at his option  "without  good reason" prior to May 1,
2000.

In fiscal 1999, the Company issued 515,000 shares of common stock and options to
purchase  436,000 shares of the Company's common stock at prices ranging between
$.594 and $.719 in connection with employment and consulting agreements.

[8] Income Per Share

                                             For the Year Ended October 31, 1999
                                           -------------------------------------
                                                                       Per Share
                                              Income      Shares        Amount
Basic EPS:
  [Loss] Income Available to Common
   Stockholders                            $(4,978,448)  7,357,235   $    (.68)

Effect of Dilutive Securities:
  Convertible Preferred Stock                       --          --
  Warrants/Options                                  --          --
                                           -----------  ----------

Diluted EPS:
  [Loss] Income Available to Common
   Stockholders Plus Assumed Conversions   $(4,978,448)  7,357,235   $    (.68)
                                           -----------  ----------   ---------

Incentive  stock  options  to  purchase  612,041  shares  of  common  stock  and
non-incentive  stock options and warrants to purchase  954,100  shares of common
stock  were  outstanding  at  October  31,  1999 but were  not  included  in the
computation  of diluted EPS because  they were  antidilutive.  These  securities
could potentially dilute earnings per share in the future.

                                             For the Year Ended October 31, 1998
                                          --------------------------------------
                                                                       Per Share
                                             Income       Shares        Amount
Basic EPS:
  Income Available to Common Stockholders $   596,583    7,196,299   $      .08

Effect of Dilutive Securities:
  Convertible Preferred Stock                      --      278,137
  Warrants/Options                                 --      492,568
                                          -----------   ----------

Diluted EPS:
  Income Available to Common Stockholders
   Plus Assumed Conversions               $   596,583    7,967,004   $      .07
                                          -----------   ----------   ----------

Warrants  and options to purchase  5,448,339  shares of common stock at $3.00 to
$6.75 per share were  outstanding  at October 31, 1998 but were not  included in
the  computation  of diluted EPS because the  exercise  price of these items was
greater than the average  market price of the common  shares.  These  securities
could potentially dilute earnings per share in the future.  Warrants to purchase
5,253,339 shares of common stock expired in November 1998.


                                      F-14

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #8
- ------------------------------------------------------------------------------


[8] Income Per Share [Continued]

                                           For the Year Ended October 31, 1997
                                          ------------------------------------
                                                                       Per Share
                                              Income       Shares       Amount
Basic EPS:
  Income Available to Common Stockholders   $3,199,915    6,685,155  $       .48

Effect of Dilutive Securities:
  Convertible Preferred Stock                       --      244,108
  Warrants/Options                                  --      450,650
                                            ----------   ----------

Diluted EPS:
  Income Available to Common Stockholders
   Plus Assumed Conversions                 $3,199,915    7,379,913  $       .43
                                            ----------   ----------  -----------

Warrants  and options to purchase  5,651,673  shares of common stock at $1.50 to
$6.75 per share were  outstanding  at October 31, 1997 but were not  included in
the  computation  of diluted EPS because the  exercise  price of these items was
greater than the average  market price of the common  shares.  These  securities
could potentially dilute earnings per share in the future.

[9] Stock Options and Warrants

[A] Employment  Incentive  Stock Options - In November  1989,  the  shareholders
approved  and the Company  adopted the 1989  Employee  Stock  Option Plan ["1989
Plan"] which provides for the granting of 666,667 shares of common stock.  Under
the terms of its stock option plans,  incentive stock options to purchase shares
of the  Company's  common  stock are  granted  at a price not less than the fair
market value of the common stock at the date of grant.  These stock  options are
exercisable  up to ten years  from the date of grant.  At October  31,  1999 and
1998,  there were 12,291  shares  reserved for future  grants under the plan. No
stock appreciation rights have been granted. In May 1997, the Company's board of
directors approved the cancellation of all of the outstanding employee incentive
stock options for new options at an exercise  price of $.71875  which  reflected
fair market value. Following is a summary of transactions:
                                                               Weighted Average
                                                   Shares Under Exercise Price
                                                       Options    Per Share

Outstanding at October 31, 1996                       482,044      $  .72
Granted During the Year                               210,000         .76
Expired During the Year                               (34,334)        .72
Exercised During the Year                                  --          --
                                                    ---------      ------

  Outstanding and Eligible for Exercise at
   October 31, 1997                                   657,710         .73
  ------------------

Granted During the Year                                    --          --
Expired During the Year                                (3,334)        .72
Exercised During the Year                              (8,334)        .72
                                                    ---------      ------

  Outstanding and Eligible for Exercise at
   October 31, 1998                                   646,042         .73
  -----------------

Granted During the Year                                    --          --
Expired During the Year                               (34,001)        .72
Exercised During the Year                                  --          --
                                                    ---------      ------

  Outstanding and Eligible for Exercise at
    October 31, 1999                                  612,041      $  .73
  ------------------                                  =======      ======


                                      F-15

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #9
- ------------------------------------------------------------------------------




[9] Stock Options and Warrants [Continued]

                                        Outstanding and Exercisable Options
                                        -----------------------------------
                                                     Weighted
                                                      Average
                                        Number of   Remaining  Weighted Average
                                      Shares Under  Contractual  Exercise Price
Exercise Price Range                     Option        Life         Per Share
- --------------------                     ------        ----         ---------

$.71875 to $.790625 Per Share            612,041      8 Years       $     .73

The weighted  average grant date fair value of options  granted  during the year
ended October 31, 1997 was $.2486 per share.

The Company  accounts  for these  stock-based  compensation  awards to employees
under the intrinsic value method in accordance with Accounting  Principles Board
Opinion No. 25 "Accounting  for Stock Issued to Employees."  Total  compensation
cost recognized against income for stock-based employee  compensation awards was
$-0- for the years ended October 31, 1999, 1998 and 1997.

[B] Non Incentive Stock Options and Warrants -  Non-incentive  stock options and
warrants may be granted to employees or non-employees at fair market value or at
a price less than fair  market  value of the common  stock at the date of grant.
The following is a summary of transactions:

                                                                     Weighted
                                                     Shares Under     Average
                                                       Options    Exercise Price
                                                    and Warrants     Per Share
                                                    ------------     ---------

  Outstanding and Eligible for Exercise at
   October 31, 1996                                    6,022,380      $ 4.63
  -----------------

Granted During the Year                                  381,300         .72
Expired During the Year                                 (584,871)       1.45
Exercised During the Year                                     --          --
                                                      ----------      ------

  Outstanding and Eligible for Exercise at
    October 31, 1997                                   5,818,809        4.71
  ------------------

Granted During the Year                                       --          --
Expired During the Year                                 (206,668)       5.00
Exercised During the Year                                (35,200)        .72
                                                      ----------      ------

  Outstanding and Eligible for Exercise at
     October 31, 1998                                  5,576,941        4.73
  -------------------

Granted During the Year                                  436,000         .87
Expired During the Year                               (5,058,841)       5.03
Exercised During the Year                                     --          --
                                                      ----------      ------

  Outstanding and Eligible for Exercise at
     October 31, 1999                                    954,100      $ 1.37
  -------------------                                 ==========      ======




                                      F-16

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #10
- ------------------------------------------------------------------------------


[9] Stock Options and Warrants [Continued]

During the year ended  October 31,  1997,  35,200  shares  under  warrants  were
granted to three non-  employees and 23,334 shares under  warrants were canceled
for new warrants at a price of $.71875 which represents fair market value at the
time of grant.  The fair value of each warrant granted was estimated on the date
of grant  using  the  Black-Scholes  option-pricing  model  with  the  following
assumptions:  a  weighted  average  risk-free  interest  rate of 6%, a  weighted
average  expected life of 1 year based on Company  expectations and the required
minimum two year holding period,  and a weighted average expected  volatility of
84.09%.  Dividends are not expected to be available to  shareholders  during the
expected life of the warrants.  The fair value of these options issued in May of
1997  of  $13,423  [$.2486  per  share]  has  been  accounted  for  as  deferred
compensation  for the year ended October 31, 1997 and is being expensed over the
term of the agreements. Total compensation expense recognized against income for
this deferred compensation was $2,848, $2,848 and $2,254, respectively,  for the
years ended October 31, 1999, 1998 and 1997.

During the years ended  October 31, 1999 and 1997,  436,000 and 346,100  shares,
respectively,  under options were granted to employees. The Company accounts for
these  options under the intrinsic  value method in accordance  with  Accounting
Principles  Board  Opinion No. 25  "Accounting  for Stock Issued to  Employees."
Total  compensation  cost  recognized  against income for employee  nonincentive
stock option and warrants  was $-0- for the years ended  October 31, 1999,  1998
and 1997.

                                Outstanding and Exercisable Options and Warrants
                                ------------------------------------------------
                                                    Weighted
                                       Number of    Average
                                     Shares Under  Remaining Weighted Average
                                      Options and Contractual Exercise Price
Exercise Price Range                    Warrants     Life        Per Share
- --------------------                    --------     ----        ---------

Options - $.594 to $.719 Per Share       498,100    5 Years       $   .69
Options - $1.00 Per Share                286,000    4 Years       $  1.00
Options - $3.00 Per Share                 20,000    1 Year        $  3.00
Options - $4.125 Per Share               150,000 Expires 4/00     $ 4.125
                                      ----------

                                         954,100

These options have weighted average remaining  contractual lives of three years.
The weighted  average grant date fair value of options  granted  during the year
ended  October 31, 1997 was $.2486 per share.  The weighted  average  grant date
fair value of options  granted during the year ended October 31, 1999 was $.3485
per share.

[A] and [B] Pro Forma - Had  compensation  cost been  determined on the basis of
fair value  pursuant to SFAS No.  123,  for the 612,041  shares  under  employee
incentive  stock  options  and the 436,000 and  346,100  shares  under  employee
nonincentive  stock  options and warrants for the years ended  October 31, 1999,
1998 and 1997, net income and earnings per share would have been as follows:

                                        1 9 9 9       1 9 9 8     1 9 9 7
                                        -------       -------     -------
Net [Loss] Income:
  As Reported                         $(4,978,448) $   596,583   $3,199,915
                                      ===========  ===========   ==========
  Pro Forma                           $(5,130,411) $   596,583   $2,950,000
                                      ===========  ===========   ==========

Basic [Loss] Earnings Per Share:
  As Reported                         $     (.68)  $       .08   $      .48
                                      ==========   ===========   ==========
  Pro Forma                           $     (.70)  $       .08   $      .44
                                      ==========   ===========   ==========

Diluted [Loss] Earnings Per Share:
  As Reported                         $     (.68)  $       .07   $      .43
                                      ==========   ===========   ==========
  Pro Forma                           $     (.70)  $       .07   $      .40
                                      ==========   ===========   ==========

                                      F-17

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #11
- ------------------------------------------------------------------------------




[9] Stock Options and Warrants [Continued]

[B] Non Incentive Stock Options and Warrants [Continued]

The fair  value  used in the pro  forma  data was  estimated  by using an option
pricing model which took into account as of the grant date,  the exercise  price
and the expected life of the option,  the current price of the underlying  stock
and its expected  volatility,  expected dividends on the stock and the risk-free
interest rate for the expected term of the option.  The following is the average
of the data used for the following items.

                   Risk-Free                        Expected        Expected
Year Ended       Interest Rate    Expected Life    Volatility       Dividends

October 31, 1997      6%             1 Year         84.09%            None
October 31, 1999      6%             1 Year     97.89% -104.28%       None

[10] Employment Contracts and Consulting Agreements

The  Company  has entered  into  various  employment  contracts  and  consulting
agreements for periods ranging from one to seven years. At October 31, 1999, the
aggregate  minimum  commitment  under these contracts and agreements,  excluding
commissions or consumer price index increases, was approximately as follows:

October 31,
  2000                  $ 1,526,000
  2001                    1,345,000
  2002                    1,174,000
  2003                      710,000
  2004                      683,000
  Thereafter                277,000
                        -----------

  Total                 $ 5,715,000
  -----                 ===========

Some of these agreements  provide bonuses and commissions  based on a percentage
of collected revenues ranging from 1% to 10% on accounts referred by or serviced
by the employee or consultant.

In addition to the above,  eight employment  agreements which provide for annual
aggregate  minimum  commitments  of  approximately  $630,000 have no termination
dates.

The Company pays premiums on life insurance policies for three key officers.  In
the event that any of these officers leave the Company, they are required to pay
the Company back for premiums paid on their policies. In the event of death, the
benefit  paid to the  beneficiary  is reduced by the amount of premiums  paid on
behalf of the individual by the Company.  At October 31, 1999 and 1998, $695,726
and $567,769 is included in other assets which represents the amount of premiums
paid to date.  At October  31,  1999 and 1998,  cash  surrender  values on these
policies were in excess of amounts receivable.


                                      F-18

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #12
- ------------------------------------------------------------------------------


[11] Capitalized Lease Obligations

The Company  leases  various  assets under  capital  leases  expiring in 2004 as
follows:

                                               October 31,
                                               -----------
                                           1 9 9 9    1 9 9 8
                                           -------    -------

Medical Equipment                         $1,325,238 $1,168,027
Furniture and Fixtures                           --      11,565
                                          ---------   ---------

Totals                                    1,325,238   1,179,592
Less: Accumulated Depreciation              385,032     461,259
                                          ---------   ---------

  Net                                     $ 940,206  $  718,333
  ---                                     =========  ==========

Depreciation  expense on assets under capital leases was $202,589,  $198,280 and
$83,853 for the years ended October 31, 1999, 1998 and 1997, respectively.

Aggregate future minimum rentals under capital leases are:

Years ended
October 31,
  2000                                         $  430,580
  2001                                            331,333
  2002                                            232,001
  2003                                            185,164
  2004                                             87,771
  Thereafter                                           --
                                               ----------

  Total                                         1,266,849
  Less:  Interest                                 278,060
                                               ----------

  Present Value of Minimum Lease Payments      $  988,789
  ---------------------------------------      ==========

[12] Commitments and Contingencies

The Company leases various office and laboratory  facilities and equipment under
operating  leases  expiring from 1999 to 2006.  Several of these leases  contain
renewal options for three to five year periods.

Total expense for property and equipment  rental for the years ended October 31,
1999,  1998 and 1997 was $2,848,225,  $2,180,112 and  $1,796,839,  respectively.
There were no contingent rental amounts due through October 31, 1999.

Aggregate  future  minimum rental  payments on  noncancelable  operating  leases
(exclusive of several month to month leases aggregating approximately $1,000,000
annually) are as follows:

                                                 Property      Equipment
October 31,
  2000                                         $  789,619   $   770,065
  2001                                            613,292       556,647
  2002                                            470,400       325,690
  2003                                            442,789       230,479
  2004                                            166,463       121,171
  Thereafter                                        8,017            --
                                               ----------   -----------

   Totals                                      $2,490,580   $ 2,004,052
   ------                                      ==========   ===========

                                      F-19

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #13
- ------------------------------------------------------------------------------



[13] Litigation

In the normal course of business, the Company is exposed to a number of asserted
and unasserted potential claims. In the opinion of management, the resolution of
these matters will not have a material adverse effect on the Company's financial
position or results of operations [See Note 22C].

The Company is being  represented by counsel in connection  with various reviews
being  conducted  by  the  Company's  Medicare  carrier.   One  review  involved
overpayments  that occur in the normal course of business.  The Company believes
the overpayment will be approximately  $150,000,  of which approximately $75,000
has been remitted to Medicare.  Counsel  representing the Company in this matter
has advised  that he cannot offer any opinion or  projection  at this time as to
whether  the  anticipated  liability  will be resolved at $150,000 or whether it
will be increased.  Counsel has advised that based upon his review of documents,
many of the claims that  Medicare  thought were  duplicate  payments were not in
fact duplicates,  but rather were properly billed.  Counsel also advised that in
view of the complexity of the issue, he believes the final  overpayment  will be
an amount negotiated between the Company and Medicare.

On December 30, 1996, the Company commenced a lawsuit against SmithKline Beecham
Clinical  Laboratories  ["SBCL"]  alleging that SBCL  materially  and repeatedly
breached its  obligations  and its  representations  and warranties  made in the
Asset Agreement and the Non-Competition  Agreement pursuant to which the Company
purchased   certain  assets  from  SBCL  and  claims   unspecified   amounts  of
compensatory  and  punitive  damages  and  related  costs.  As a  result  of its
allegations  against SBCL, the Company did not make any payments with respect to
the $600,000  note  payable.  In October  1998,  the Company and SBCL  exchanged
general releases for this lawsuit and no executory obligations were imposed upon
the Company by the settlement  agreement.  Therefore,  the Company cancelled the
$600,000 note payable as well as the related goodwill of approximately $550,000.
The  settlement  was subject to the consent of the Company's  principal  lending
bank which consent was received in January 1999. In addition, management decided
to no longer pursue the hemo-dialysis business and accordingly made revisions to
its future business endeavors.  Accordingly,  the Company recorded an impairment
of approximately  $2,900,000 on related  hemo-dialysis  assets in fiscal 1999 of
which  $2,000,000  was for related  accounts  receivable  and  $900,000  was for
goodwill [See Note 2].

[14] Insurance

The Company  maintains  professional  liability  insurance of  $3,000,000 in the
aggregate,  with a per occurrence limit of $1,000,000 . In addition, the Company
maintains excess commercial insurance of $2,000,000 per occurrence.  The Company
believes,  but cannot  assure,  that its insurance  coverage is adequate for its
current  business needs. A determination  of Company  liability for uninsured or
underinsured  acts or  omissions  could  have a material  adverse  affect on the
Company's operations.

[15] Significant Risks and Uncertainties

[A]  Concentrations of Credit Risk - Cash - At October 31, 1999, the Company had
approximately  $1,846,000  in  cash  and  certificate  of  deposit  balances  at
financial institutions which were in excess of the federally insured limits.

At October  31,  1998,  the  Company had  approximately  $6,545,000  in cash and
certificate of deposit balances at financial  institutions  which were in excess
of the  federally  insured  limits.  Approximately  $3,680,000  of  this  amount
represented  collateral  for demand loans with the same  financial  institution.
[See restricted certificates of deposit on consolidated balance sheet].


                                      F-20

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #14
- ------------------------------------------------------------------------------




[15] Significant Risks and Uncertainties [Continued]

[B]  Concentration  of Credit  Risk -  Accounts  Receivable  - Credit  risk with
respect to accounts receivable is generally  diversified due to the large number
of  patients  comprising  the client  base.  The Company  does have  significant
receivable  balances  with  government  payors and various  insurance  carriers.
Generally,  the Company does not require collateral or other security to support
customer  receivables,  however,  the Company continually monitors and evaluates
its client  acceptance and collection  procedures to minimize  potential  credit
risks  associated with its accounts  receivable and establishes an allowance for
uncollectible  accounts  and  as  a  consequence,  believes  that  its  accounts
receivable  credit risk  exposure  beyond such  allowance is not material to the
financial statements.

A number of proposals  for  legislation  continue to be under  discussion  which
could  substantially  reduce  Medicare and Medicaid  reimbursements  to clinical
laboratories. Depending upon the nature of regulatory action, and the content of
legislation,  the Company could  experience a  significant  decrease in revenues
from Medicare and Medicaid,  which could have a material  adverse  effect on the
Company.  The  Company is unable to predict,  however,  the extent to which such
actions will be taken.

[16] Acquisitions

On April 9, 1998,  the Company  acquired the assets and certain  liabilities  of
Medilabs,  Inc.  ["MLI"] from LTC Service and  Holdings,  Inc.  ["Holdings"],  a
wholly-owned   subsidiary  of  Long-Term  Care  Services,   Inc.  ["LTC"].   The
acquisition  was effective  April 9, 1998 for  accounting  purposes and is being
accounted for under the purchase  method.  The operations of Medilabs,  Inc. are
included in the  Company's  results of operations  commencing  April 9, 1998. In
connection with the acquisition of MLI, certain key employees signed  employment
agreements with the Company for an unspecified period which included a six month
non-competition  clause. In addition, LTC, Holdings, two affiliated corporations
and an employee of LTC signed non-competition agreements.

[17] Fair Value of Financial Instruments

For certain financial  instruments,  including cash and cash equivalents,  trade
receivables,  trade  payables,  and  short-term  debt, it was estimated that the
carrying amount  approximated fair value for the majority of these items because
of their short  maturities.  The fair value of the Company's  long-term  debt is
estimated based on the quoted market prices for similar issues or by discounting
expected  cash flows at the rates  currently  offered to the Company for debt of
the same remaining maturities.

                                               O c t o b e r  3 1,
                                    -----------------------------------------
                                           1 9 9 9               1 9 9 8
                                    --------------------  -------------------
                                     Carrying    Fair      Carrying      Fair
                                      Amount     Value      Amount       Value

Long-Term Debt                     $2,000,000 $2,000,000  $3,306,617  $3,306,617
Capitalized Lease Obligations      $  680,538 $  654,764  $  400,975  $  381,637

Due to the non-interest bearing nature and unspecified payment terms, it was not
practicable to estimate the fair value of amounts due from related  parties [See
also Note 5].

[18] Health Insurance Plan

The Company has a limited  self-funded  health  insurance plan for its employees
under which the Company pays the initial $50,000 of covered medical expenses per
person per year.  The Company has a contract  with an insurance  carrier for any
excess.  Health insurance expense for the years ended October 31, 1999, 1998 and
1997, totaled approximately $287,000, $279,000 and $232,000, respectively.

                                      F-21

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #15
- ------------------------------------------------------------------------------


[19] Employee Benefit Plan

The Company sponsors the Bio-Reference Laboratories,  Inc. 401(k) Profit-Sharing
Plan.  Employees  become eligible for  participation  after attaining the age of
eighteen  and  completing  one  year  of  service.  Participants  may  elect  to
contribute  up to ten  percent  of their  compensation,  as  defined in the Plan
Adoption  Agreement,  to a maximum allowed by the Internal Revenue Service.  The
Company  may  choose  to make a  matching  contribution  to the  plan  for  each
participant  who has elected to make tax-  deferred  contributions  for the plan
year, at a percentage  determined  each year by the Company.  For the year ended
October  31,  1999,  1998 and 1997,  the Company  elected  not to make  matching
contributions  to  the  plan.  If  the  Company  elects  to  match   participant
contributions  in the future,  the  employer  contribution  will be fully vested
after the fifth year of service.

[20] Non-recurring Gain on Sale of Intangible Assets

On  September  30, 1997,  the Company  entered into an agreement to sell certain
customer lists, its "GenCare"  tradename and rights under two GenCare  contracts
to another  laboratory  for  $4,600,000 in cash and  $1,400,000  payable in four
equal  installments  every six months beginning April 1, 1998,  provided however
that certain  target  revenues are reached.  If target  revenues are not reached
amounts  payable  under  the  contract  will be  decreased  up to a  maximum  of
$700,000.  The Company and certain of its officers  entered into a  noncompetion
agreement with the purchaser as part of this agreement.  The Company  recorded a
non-recurring  gain of $2,025,689 and $333,900 during October 31, 1997 and 1998,
respectively,  related to this sale. The $700,000 in contingent receivables were
included in the  calculation of gain on this sale for the year ended October 31,
1998 when target revenues were reached.  This receivable was collected in fiscal
1999.

[21] New Authoritative Accounting Pronouncements

The Financial  Accounting Standards Board ["FASB"] issued Statement of Financial
Accounting  Standards ["SFAS"] No. 137,  "Accounting for Derivative  Instruments
and Hedging  Activities-Deferral  of Effective Date of FASB Statements No. 133."
The Statement  defers for one year the effective date of FASB Statement No. 133,
"Accounting  for Derivative  Instruments and Hedging  Activities."  The rule now
will apply to all fiscal  quarters of all fiscal years  beginning after June 15,
2000. The Statement will require the Company to recognize all derivatives on the
balance sheet at fair value. Derivatives that are not hedges must be adjusted to
fair value through income. If the derivative is a hedge, depending on the nature
of the hedge,  changes in the fair value of  derivatives  will  either be offset
against  the  change in fair value of the hedged  assets,  liabilities,  or firm
commitments through earnings or recognized in other  comprehensive  income until
the  hedged  item is  recognized  in  earnings.  The  ineffective  portion  of a
derivative's  change in fair value will be  immediately  recognized in earnings.
The  adoption of SFAS No. 137 is not  expected to have a material  impact on the
Company's consolidated results of operation, financial position or cash flows.

[22] Subsequent Events

[A] Asset Purchase Agreements - On December 2, 1999, the Company entered into an
agreement to purchase  certain  assets  utilized by a company that is engaged in
selling Internet website design and other Internet-oriented  services to medical
professionals and other healthcare  professionals.  Bio-Reference  Laboratories,
Inc.  delivered  140,000  shares  of its  common  stock in  payment  for the web
business  along with  60,000  shares of its common  stock in  consideration  for
related  non-competition  agreements.  The fair value of the  200,000  shares of
common stock is approximately  $200,000.  The Company has also paid $10,000 to a
former  executive  officer  of the  website  company  and  executed  a one  year
consulting  agreement  with the website  company for $40,000 in the initial year
and $50,000 in any subsequent  year. The Company granted the website business an
option to purchase a maximum of 100,000  shares of the  Company's  common  stock
exercisable at $3.00 per share with certain vesting restrictions.



                                      F-22

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS, Sheet #16
- ------------------------------------------------------------------------------



[22] Subsequent Events [Continued]

[A] Asset  Purchase  Agreements  [Continued] - On December 14, 1999, the Company
entered into an agreement to purchase  certain assets utilized by a company that
is engaged in the  manufacture  of certain  health  food  products.  The Company
delivered  180,000  shares of its common  stock in payment  for the health  food
business  along with 20,000  shares of its common stock in  consideration  for a
related non-  competition  agreement.  The Company  entered  into an  employment
agreement in connection with this purchase. The fair value of the 200,000 shares
of common  stock is  approximately  $200,000.  The  Company  also  entered in an
employment  agreement for an annual salary of $150,000  plus  commissions  and a
signing bonus of $100,000 in 24 monthly installments.

[B] Bank Waivers - On January 26,  2000,  the Company  obtained  from PNC Bank a
waiver for the Company's October 31, 1999 default on its tangible net worth, net
worth and capital expenditure covenants.

[C] NJ Medicaid  Pending  Settlement - In January  2000,  the Company  commenced
negotiations with New Jersey Medicaid regarding a claim made against the Company
by the State of New  Jersey.  The alleged  claim was  received by the Company on
December 28, 1999.  The claim  alleged  that the Company was  reimbursed  by the
State for claims submitted which, although authorized by the physician,  did not
bear the physician's  actual  signature.  The Company  immediately  disputed the
claim.

The  Company  believes it has been  compliant  with all  requirements  regarding
claims  submitted for payment by New Jersey Medicaid and in fact requires actual
physician  signatures before it bills New Jersey Medicaid.  However, the Company
and New Jersey Medicaid entered into a compromise  agreement on January 19, 2000
to a full  settlement for this claim in the amount of $227,000.  The Company has
accrued  this  settlement  amount  in  its  October  31,  1999  financials.  The
settlement is subject to the parties'  execution of a written  agreement setting
forth its terms and to the  approval of the  Director of the Division of Medical
Assistance. Approval of the settlement is being recommended to the Director.





                      .   .   .   .   .   .   .   .   .   .

                                      F-23

<PAGE>



                          INDEPENDENT AUDITOR'S REPORT

To the Board of Directors and Stockholders of
  Bio-Reference Laboratories, Inc.
  Elmwood Park, New Jersey



            Our  report  on our  audit  of the  basic  financial  statements  of
Bio-Reference  Laboratories,  Inc. and its subsidiary  appears on page F-1. That
audit was conducted for the purpose of forming an opinion on the basic financial
statements  taken as a whole.  The  supplemental  schedule II is  presented  for
purposes of complying  with the Securities  and Exchange  Commissions  Rules and
Regulations  under the  Securities  Exchange Act of 1934 and is not  otherwise a
required  part of the basic  financial  statements.  Such  information  has been
subjected to the auditing procedures applied in the audit of the basic financial
statements,  and in our opinion,  is fairly  stated in all material  respects in
relation to the basic financial statements taken as a whole.






                                          MOORE STEPHENS, P. C.
                                          Certified Public Accountants.
Cranford, New Jersey
January 7, 2000

                                      F-24

<PAGE>



BIO-REFERENCE LABORATORIES, INC. AND SUBSIDIARY
- ------------------------------------------------------------------------------


SCHEDULE II - VALUATION AND QUALIFYING  ACCOUNTS FOR THE YEARS ENDED OCTOBER 31,
1999, 1998 AND 1997.
- ------------------------------------------------------------------------------




         (a)                        (b)        (c)         (d)          (e)

                                Balance at Charged to  Deductions     Balance
                                 Beginning  Cost and  To Valuation    at End
     Description                 of Period  Expenses    Accounts     of Period
     -----------                 ---------  --------    --------     ---------


Year Ended October 31, 1999
  Allowance for Doubtful
  Accounts and Contractual
  Credits                      $13,494,475 $85,674,430 $(83,855,970) $15,312,935
                               =========== =========== ============  ===========

Year Ended October 31, 1998
  Allowance for Doubtful
  Accounts and Contractual
  Credits                      $ 8,564,436 $72,137,649 $(67,207,610) $13,494,475
                               =========== =========== ============  ===========

Year Ended October 31, 1997
  Allowance for Doubtful
  Accounts and Contractual
  Credits                      $ 5,357,096 $47,593,419 $(44,386,079) $8,564,436
                               =========== =========== ============  ==========



                                        F-25






                                 Exhibit 3.1.3

                        CERTIFICATE OF AMENDMENT TO THE

                        CERTIFICATE OF INCORPORATION OF

                       BIO-REFERENCE LABORATORIES, INC.


To:   The Secretary of State
      State of New Jersey


      Pursuant to the provisions of Section 14A:7-2(2),  Corporations,  General,
of  the  New  Jersey  Statutes,   the  undersigned   corporation  executes  this
certificate of amendment to its certificate of incorporation:
      1.    The name of the corporation (hereinafter called the
"Corporation") is Bio-Reference Laboratories, Inc.
      2.  The  following  resolution  has  been  duly  adopted  by the  Board of
Directors of the  Corporation  as required by  Subsection  14A:7-2(3) of the New
Jersey Business Corporation Act.
      RESOLVED,  that pursuant to the authority vested in the Board of Directors
      of this  Corporation in accordance  with the provisions of its Certificate
      of Incorporation, the Board of Directors hereby creates a series of Series
      A Preferred Stock,  $.10 par value, of the Corporation,  and hereby states
      the  designation  and  amount  thereof  and  fixes  the  relative  rights,
      preferences  and  limitations  thereof (in addition to the  provisions set
      forth in the Certificate of Incorporation  of the  Corporation,  which are
      applicable to the  preferred  stock of all classes and series) as follows,
      so that ARTICLE (3) of the Corporation's  Certificate of Incorporation be,
      and it hereby is, amended by deleting the present  Article  (3)B(1) and by
      inserting  therein the following new paragraph B(1) immediately  following
      ARTICLE (3)(B), paragraph 7:

            "B(1).      Series A Senior Preferred Stock.
                        -------------------------------

            (a)   Designation and Amount.  An aggregate of
                  ----------------------
      604,078 shares of Series A Preferred Stock, $.10 par
      value, of the Corporation are hereby constituted as a

                                      1

<PAGE>



      series  designated  as "Series A Senior  Preferred  Stock" (the  "Series A
      Senior  Preferred  Stock").  Such  number of shares  may be  increased  or
      decreased by resolution of the Board of Directors.


            (b)  Vote.  Except  as  may  otherwise  be  required  by  law,  this
      Certificate  of  Incorporation  or the  provisions  of the  resolution  or
      resolutions  as may be  adopted  by the  Board of  Directors  pursuant  to
      paragraph  (B) of this  Article  THIRD,  each  holder  of  Series A Senior
      Preferred  Stock  shall have one vote in respect of each share of Series A
      Senior  Preferred  Stock held by such holder on each matter  voted upon by
      the stockholders. The holders of shares of Series A Senior Preferred Stock
      and the holders of shares of Common Stock and any other  capital  stock of
      the  Corporation  having  general voting rights shall vote together as one
      class  on  all  matters  submitted  to  a  vote  of  stockholders  of  the
      Corporation.

            (c) Dividends.  Holders of Series A Senior  Preferred Stock shall be
      entitled to be paid dividends on a per share basis equal to dividends,  if
      any paid on a per share basis to holders of Common Stock, at the time such
      dividends are paid with respect to the Common Stock.

            (d)  Liquidation   Rights.   After   distribution  in  full  of  any
      preferential  amount (fixed in accordance with the provisions of paragraph
      (B) of this Article  THIRD),  if any, to be  distributed to the holders of
      Preferred  Stock in the event of  voluntary  or  involuntary  liquidation,
      distribution  or  sale  or  assets,  dissolution  or  winding-up  of  this
      Corporation,  the holders of the Series A Senior  Preferred Stock together
      with the holders of the Common  Stock shall be entitled to receive all the
      remaining assets of this Corporation, tangible and intangible, of whatever
      kind available for  distribution to  stockholders,  ratably on a per share
      basis  in  proportion  to the  number  of  shares  of the  Series A Senior
      Preferred Stock and the Common Stock held by each.

            (e) Conversion Rights. From and after the Date of Issuance and prior
      to the close of  business  on May 1,  2007,  each share of Series A Senior
      Preferred  Stock shall be convertible,  at the option of the holder,  upon
      payment  of the  Conversion  Price,  into one share of Common  Stock.  The
      initial  Conversion Price shall be $.75 per share. In the event of a stock
      dividend,  combination, stock split or reverse stock split, the Conversion
      Price and the number of shares of Common Stock into which the Series A

                                      2

<PAGE>



      Senior Preferred Stock may be converted shall be appropriately adjusted."

      3. The foregoing  resolution was duly adopted by the Board of Directors of
the  Corporation  on May 17, 1997,  pursuant to authority  granted under Section
14A:7-2(2) of the New Jersey Business Corporation Act.
      4. The Certificate of  Incorporation of the Corporation is amended so that
the designation and number of shares of the series of Preferred Stock acted upon
in  the  foregoing  resolution,   and  the  relative  rights,   preferences  and
limitations of such series, are as stated in the resolution.
      IN WITNESS  WHEREOF,  Bio-Reference  Laboratories,  Inc.  has caused  this
Certificate of Amendment to the Certificate of Incorporation to be duly executed
this 25th day of March, 1998.

                                    BIO-REFERENCE LABORATORIES, INC.



                                 By /s/Marc D. Grodman
                                   -------------------
                                    Marc D. Grodman, President

ATTEST:



/s/Sam Singer
Sam Singer, Secretary

                                      3





                                 Exhibit 3.1.4
                           CERTIFICATE OF AMENDMENT
                                    TO THE
                         CERTIFICATE OF INCORPORATION

                                      of

                       BIO-REFERENCE LABORATORIES, INC.


To:   The Secretary of State
      State of New Jersey

      Pursuant to the provisions of Section 14A:7-2(2),  Corporations,  General,
of  the  New  Jersey  statutes,   the  undersigned   corporation  executes  this
certificate of amendment to its certificate of incorporation:

      1.    The name of the corporation (hereinafter called the
"Corporation") is Bio-Reference Laboratories, Inc.

      2.  The  following  resolution  has  been  duly  adopted  by the  Board of
Directors of the  Corporation  as required by  Subsection  14A:7-2(3) of the New
Jersey Business Corporation Act.

      RESOLVED,  that pursuant to the authority vested in the Board of Directors
      of the Corporation in accordance with the provisions of its Certificate of
      Incorporation, the Board of Directors hereby creates a series of Preferred
      Stock,  $.10  par  value,  of  the  Corporation,  and  hereby  states  the
      designation and amount thereof and fixes the relative rights,  preferences
      and  limitations  thereof (in addition to the  provisions set forth in the
      Certificate of Incorporation  of the Corporation,  which are applicable to
      the preferred stock of all classes and series) as follows, so that ARTICLE
      (3) of the  Corporation's  Certificate of Incorporation  be, and it hereby
      is, amended by inserting therein the following  paragraph B(2) immediately
      following ARTICLE (3)(B), paragraph 7, paragraph B(1):

            B(2). Series A Junior Participating Preferred Stock.
                  ----------------------------------------------

      Section 1.  Designation  and Amount.  The shares of such  series  shall be
designated as "Series A Junior Participating  Preferred Stock" and the number of
shares constituting such series shall be 3,000.

      Section 2.        Dividends and Distributions.  (A) Subject to
the prior and superior rights of the holders of any shares of any
series of Preferred Stock ranking prior and superior to the shares

                                      1

<PAGE>



of Series A Junior Participating Preferred Stock with respect to dividends,  the
holders  of shares of Series A Junior  Participating  Preferred  Stock  shall be
entitled to receive,  when,  as and if declared by the Board of Directors out of
funds legally available for the purpose,  quarterly dividends payable in cash on
the 15th day of March, June, September and December in each year (each such date
being referred to herein as a "Quarterly Dividend Payment Date"),  commencing on
the first Quarterly Dividend Payment Date after the first issuance of a share or
fraction  of a share of Series A Junior  Participating  Preferred  Stock,  in an
amount per share  (rounded to the nearest cent) equal to the greater of (a) $500
or (b) subject to the provision for  adjustment  hereinafter  set forth,  10,000
times the aggregate per share amount of all cash dividends, and 10,000 times the
aggregate per share amount (payable in kind) of all non-cash  dividends or other
distributions  other  than a  dividend  payable  in shares of Common  Stock or a
subdivision of the outstanding  shares of Common Stock (by  reclassification  or
otherwise),  declared  on the Common  Stock,  par value  $.01 per share,  of the
Corporation  (the "Common  Stock")  since the  immediately  preceding  Quarterly
Dividend Payment Date, or, with respect to the first Quarterly  Dividend Payment
Date,  since the first  issuance of any share or fraction of a share of Series A
Junior Participating  Preferred Stock. In the event the Corporation shall at any
time after  March 31,  1998 (the  "Rights  Declaration  Date") (i)  declare  any
dividend on Common Stock payable in shares of Common Stock,  (ii)  subdivide the
outstanding  Common Stock, or (iii) combine the outstanding  Common Stock into a
smaller number of shares,  then in each such case the amount to which holders of
shares  of  Series  A  Junior   Participating   Preferred  Stock  were  entitled
immediately prior to such event under clause (b) of the preceding sentence shall
be adjusted by  multiplying  such amount by a fraction the numerator of which is
the number of shares of Common Stock  outstanding  immediately  after such event
and the  denominator  of which is the number of shares of Common Stock that were
outstanding immediately prior to such event.

            (B) The Corporation  shall declare a dividend or distribution on the
Series A Junior Participating Preferred Stock as provided in paragraph (A) above
immediately  after it declares a dividend or  distribution  on the Common  Stock
(other than a dividend payable in shares of Common Stock); provided that, in the
event no dividend or  distribution  shall have been declared on the Common Stock
during the period  between  any  Quarterly  Dividend  Payment  Date and the next
subsequent  Quarterly Dividend Payment Date, a dividend of $500 per share on the
Series A Junior  Participating  Preferred Stock shall nevertheless be payable on
such subsequent Quarterly Dividend Payment Date.

            (C) Dividends shall begin to accrue and be cumulative on outstanding
shares of  Series A Junior  Participating  Preferred  Stock  from the  Quarterly
Dividend Payment Date next preceding the date of

                                      2

<PAGE>



issue of such shares of Series A Junior  Participating  Preferred Stock,  unless
the date of issue of such  shares  is  prior to the  record  date for the  first
Quarterly  Dividend  Payment  Date in which case  dividends on such shares shall
begin to accrue  from the date of issue of such  shares,  or unless  the date of
issue is a Quarterly  Dividend  Payment  Date or is a date after the record date
for the  determination  of  holders  of shares of Series A Junior  Participating
Preferred  Stock  entitled  to receive a  quarterly  dividend  and  before  such
Quarterly  Dividend Payment Date, in either of which events such dividends shall
begin to accrue and be cumulative  from such  Quarterly  Dividend  Payment Date.
Accrued but unpaid  dividends  shall not bear  interest.  Dividends  paid on the
shares of Series A Junior  Participating  Preferred Stock in an amount less than
the total  amount of such  dividends  at the time  accrued  and  payable on such
shares  shall be  allocated  pro rata on a  share-by-share  basis among all such
shares at the time outstanding. The Board of Directors may fix a record date for
the  determination  of  holders  of  shares  of  Series A  Junior  Participating
Preferred  Stock  entitled  to receive  payment of a  dividend  or  distribution
declared  thereon,  which record date shall be no more than 30 days prior to the
date fixed for the payment thereof.

      Section 3.        Voting Rights.  The holders of shares of Series
A Junior Participating Preferred Stock shall have the following
voting rights:

            (A) Subject to the provision for adjustment  hereinafter  set forth,
each share of Series A Junior  Participating  Preferred  Stock shall entitle the
holder  thereof  to  10,000  votes  on all  matters  submitted  to a vote of the
stockholders of the Corporation.  In the event the Corporation shall at any time
after the Rights  Declaration  Date (i)  declare any  dividend  on Common  Stock
payable in shares of Common Stock, (ii) subdivide the outstanding  Common Stock,
or (iii) combine the  outstanding  Common Stock into a smaller number of shares,
then in each such case the number of votes per share to which  holders of shares
of Series A Junior Participating Preferred Stock were entitled immediately prior
to such event  shall be adjusted by  multiplying  such number by a fraction  the
numerator  of  which  is the  number  of  shares  of  Common  Stock  outstanding
immediately  after  such  event and the  denominator  of which is the  number of
shares of Common Stock that were outstanding immediately prior to such event.

            (B) Except as  otherwise  provided  herein or by law, the holders of
shares of Series A Junior  Participating  Preferred Stock, the holders of shares
of Common  Stock and the holders of Series A Senior  Preferred  Stock shall vote
together as one class on all matters  submitted to a vote of stockholders of the
Corporation.

            (C)  (i)  If  at  any  time   dividends   on  any  Series  A  Junior
Participating Preferred Stock shall be in arrears in an amount

                                      3

<PAGE>



equal to six (6) quarterly dividends thereon, the occurrence of such contingency
shall mark the beginning of a period  (herein  called a "default  period") which
shall  extend  until such time when all  accrued  and unpaid  dividends  for all
previous  quarterly  dividend  periods  and for the current  quarterly  dividend
period on all  shares  of Series A Junior  Participating  Preferred  Stock  then
outstanding  shall have been declared and paid or set apart for payment.  During
each default period,  all holders of Preferred Stock  (including  holders of the
Series A Junior Participating Preferred Stock) with dividends thereon, voting as
a  class,  irrespective  of  series,  shall  have the  right  to  elect  two (2)
Directors.

                  (ii)  During any  default  period,  such  voting  right of the
holders  of  Series A Junior  Participating  Preferred  Stock  may be  exercised
initially at a special  meeting called  pursuant to  subparagraph  (iii) of this
Section 3(C) or at any annual meeting of stockholders,  and thereafter at annual
meetings of stockholders,  provided that neither such voting right nor the right
of the holders of any other series of Preferred  Stock, if any, to increase,  in
certain cases, the authorized  number of Directors shall be exercised unless the
holders of ten percent (10%) in number of shares of Preferred Stock  outstanding
shall be present in person or by proxy.  The  absence of a quorum of the holders
of Common Stock shall not affect the exercise by the holders of Preferred  Stock
of such voting  right.  At any meeting at which the holders of  Preferred  Stock
shall exercise such voting right  initially  during an existing  default period,
they shall have the right,  voting as a class,  to elect  Directors to fill such
vacancies,  if any,  in the Board of  Directors  as may then exist up to two (2)
Directors. If the number which may be so elected at any special meeting does not
amount to the required number, the holders of the Preferred Stock shall have the
right to make such  increase in the number of Directors as shall be necessary to
permit the  election by them of the  required  number.  After the holders of the
Preferred  Stock  shall have  exercised  their right to elect  Directors  in any
default  period  and  during  the  continuance  of such  period,  the  number of
Directors  shall not be increased or decreased  except by vote of the holders of
Preferred  Stock as herein  provided  or  pursuant  to the  rights of any equity
securities   ranking   senior  to  or  pari  passu  with  the  Series  A  Junior
Participating Preferred Stock.

                  (iii) Unless the holders of Preferred  Stock shall,  during an
existing  default  period,  have  previously  exercised  their  right  to  elect
Directors,  the Board of Directors may order, or any stockholder or stockholders
owning in the  aggregate  not less than ten percent (10%) of the total number of
shares of Preferred Stock outstanding,  irrespective of series, may request, the
calling of special  meeting of the holders of  Preferred  Stock,  which  meeting
shall thereupon be called by the President, a Vice-President or the

                                      4

<PAGE>



Secretary of the  Corporation.  Notice of such meeting and of any annual meeting
at which  holders of  Preferred  Stock are  entitled  to vote  pursuant  to this
paragraph  (C) (iii) shall be given to each holder of record of Preferred  Stock
by mailing a copy of such notice to him at his last  address as the same appears
on the books of the  Corporation.  Such  meeting  shall be called for a time not
earlier  than 10 days and not later  than 60 days after such order or request or
in default of the calling of such meeting may be called on similar notice by any
stockholder  or  stockholders  owning in the aggregate not less than ten percent
(10%)  of  the  total   number  of  shares  of  Preferred   Stock   outstanding.
Notwithstanding  the  provisions  of this  paragraph  (C)(iii),  no such special
meeting shall be called during the period within 60 days  immediately  preceding
the date fixed for the next annual meeting of the stockholders.

                  (iv) In any default period,  the holders of Common Stock,  and
other classes of stock of the  Corporation if  applicable,  shall continue to be
entitled to elect the whole number of  Directors  until the holders of Preferred
Stock shall have  exercised  their right to elect two (2) Directors  voting as a
class,  after the  exercise of which right (x) the  Directors  so elected by the
holders of Preferred Stock shall continue in office until their successors shall
have been elected by such holders or until the expiration of the default period,
and (y) any  vacancy  in the Board of  Directors  may  (except  as  provided  in
paragraph  (C)(ii) of this  Section  3) be filled by vote of a  majority  of the
remaining  Directors  theretofore elected by holders of the class of stock which
elected the Director whose office shall have become  vacant.  References in this
paragraph (C) to Directors elected by the holders of a particular class of stock
shall include  Directors elected by such Directors to fill vacancies as provided
in clause (y) of the foregoing sentence.

                  (v) Immediately  upon the expiration of a default period,  (x)
the right of the holders of Preferred  Stock as a class to elect Directors shall
cease,  (y) the term of any Directors  elected by the holders of Preferred Stock
as a class shall terminate, and (z) the number of Directors shall be such number
as  may  be  provided  for  in  the  certificate  of  incorporation  or  by-laws
irrespective  of any  increase  made  pursuant to the  provisions  of  paragraph
(C)(ii)  of this  Section  3 (such  number  being  subject,  however,  to change
thereafter in any manner provided by law or in the certificate of  incorporation
or by-laws).  Any vacancies in the Board of Directors effected by the provisions
of clauses (y) and (z) in the preceding  sentence may be filled by a majority of
the remaining Directors.

            (D)  Except  as  set  forth  herein,  holders  of  Series  A  Junior
Participating  Preferred  Stock  shall have no special  voting  rights and their
consent shall not be required (except to the

                                      5

<PAGE>



extent  they are  entitled  to vote with  holders  of Common  Stock as set forth
herein) for taking any corporate action.

      Section 4. Certain Restrictions. (A) Whenever quarterly dividends or other
dividends  or  distributions  payable  on  the  Series  A  Junior  Participating
Preferred  Stock as provided in Section 2 are in arrears,  thereafter  and until
all accrued and unpaid dividends and distributions,  whether or not declared, on
shares of Series A Junior  Participating  Preferred Stock outstanding shall have
been paid in full, the Corporation shall not

                  (i) declare or pay dividends on, make any other  distributions
            on, or redeem or purchase or otherwise acquire for consideration any
            shares of stock  ranking  junior  (either  as to  dividends  or upon
            liquidation,  dissolution  or  winding  up) to the  Series  A Junior
            Participating Preferred Stock;

                  (ii)   declare  or  pay   dividends   on  or  make  any  other
            distributions  on any shares of stock ranking on a parity (either as
            to dividends or upon  liquidation,  dissolution  or winding up) with
            the Series A Junior Participating  Preferred Stock, except dividends
            paid ratably on the Series A Junior  Participating  Preferred  Stock
            and all such  parity  stock on which  dividends  are  payable  or in
            arrears in  proportion  to the total amounts to which the holders of
            all such shares are then entitled;

                  (iii)   redeem  or   purchase   or   otherwise   acquire   for
            consideration  shares of any stock ranking on a parity (either as to
            dividends or upon  liquidation,  dissolution or winding up) with the
            Series A Junior  Participating  Preferred  Stock,  provided that the
            Corporation  may at any time redeem,  purchase or otherwise  acquire
            shares of any such parity  stock in exchange for shares of any stock
            of the  Corporation  ranking  junior (either as to dividends or upon
            dissolution,  liquidation  or  winding  up) to the  Series  A Junior
            Participating Preferred Stock;

                  (iv) redeem or purchase or otherwise acquire for consideration
            any shares of Series A Junior Participating  Preferred Stock, or any
            shares  of  stock  ranking  on a  parity  with  the  Series A Junior
            Participating  Preferred Stock, except in accordance with a purchase
            offer made in writing or by publication  (as determined by the Board
            of  Directors)  to all holders of such shares upon such terms as the
            Board of Directors,  after  consideration  of the respective  annual
            dividend

                                      6

<PAGE>



            rates and other  relative  rights and  preferences of the respective
            series and  classes,  shall  determine  in good faith will result in
            fair and equitable treatment among the respective series or classes.

            (B)  The  Corporation   shall  not  permit  any  subsidiary  of  the
Corporation  to purchase or otherwise  acquire for  consideration  any shares of
stock of the Corporation  unless the Corporation  could,  under paragraph (A) of
this Section 4,  purchase or  otherwise  acquire such shares at such time and in
such manner.

      Section 5. Reacquired Shares. Any shares of Series A Junior  Participating
Preferred Stock purchased or otherwise acquired by the Corporation in any manner
whatsoever  shall be  retired  and  cancelled  promptly  after  the  acquisition
thereof.  All such shares shall upon their  cancellation  become  authorized but
unissued  shares of Preferred  Stock and may be reissued as part of a new series
of Preferred  Stock to be created by resolution or  resolutions  of the Board of
Directors,  subject to the  conditions  and  restrictions  on issuance set forth
herein.

      Section 6.        Liquidation, Dissolution or Winding Up.

            (A) Upon any  liquidation  (voluntary or otherwise),  dissolution or
winding up of the Corporation,  no distribution  shall be made to the holders of
shares of stock  ranking  junior  (either as to dividends  or upon  liquidation,
dissolution or winding up) to the Series A Junior Participating  Preferred Stock
unless,  prior thereto,  the holders of shares of Series A Junior  Participating
Preferred Stock shall have received  $10,000 per share,  plus an amount equal to
accrued and unpaid dividends and distributions thereon, whether or not declared,
to the date of such payment (the "Series A Liquidation  Preference").  Following
the  payment  of the full  amount of the  Series A  Liquidation  Preference,  no
additional  distributions  shall be made to the  holders  of  shares of Series A
Junior  Participating  Preferred  Stock unless,  prior  thereto,  the holders of
shares of Common  Stock  shall have  received  an amount per share (the  "Common
Adjustment")  equal  to the  quotient  obtained  by  dividing  (i) the  Series A
Liquidation Preference by (ii) 10,000 (as appropriately adjusted as set forth in
subparagraph C below to reflect such events as stock splits, stock dividends and
recapitalizations with respect to the Common Stock) (such number in clause (ii),
the "Adjustment Number"). Following the payment of the full amount of the Series
A Liquidation Preference and the Common Adjustment in respect of all outstanding
shares of  Series A Junior  Participating  Preferred  Stock  and  Common  Stock,
respectively,  holders  of  Series A Junior  Participating  Preferred  Stock and
holders of shares of Common Stock shall receive their ratable and  proportionate
share of the remaining  assets to be  distributed in the ratio of the Adjustment
Number to 1 with respect

                                      7

<PAGE>



to such Preferred Stock and Common Stock, on a per share basis,
respectively.

            (B) In the  event,  however,  that there are not  sufficient  assets
available to permit  payment in full of the Series A Liquidation  Preference and
the  liquidation  preferences  of all other series of preferred  stock,  if any,
which rank on a parity with the Series A Junior  Participating  Preferred Stock,
then such remaining  assets shall be distributed  ratably to the holders of such
parity shares in proportion to their respective liquidation preferences.  In the
event, however, that there are not sufficient assets available to permit payment
in  full  of  the  Common  Adjustment,  then  such  remaining  assets  shall  be
distributed ratably to the holders of Common Stock.

            (C) In the event the Corporation  shall at any time after the Rights
Declaration  Date (i) declare any dividend on Common Stock  payable in shares of
Common Stock, (ii) subdivide the outstanding  Common Stock, or (iii) combine the
outstanding Common Stock into a smaller number of shares, then in each such case
the  Adjustment  Number  in  effect  immediately  prior to such  event  shall be
adjusted by multiplying  such  Adjustment  Number by a fraction the numerator of
which is the number of shares of Common Stock outstanding immediately after such
event and the  denominator of which is the number of shares of Common Stock that
were outstanding immediately prior to such event.

      Section 7. Consolidation, Merger, etc. In case the Corporation shall enter
into any  consolidation,  merger,  combination or other transaction in which the
shares  of  Common  Stock are  exchanged  for or  changed  into  other  stock or
securities,  cash and/or any other property, then in any such case the shares of
Series  A  Junior  Participating  Preferred  Stock  shall  at the  same  time be
similarly  exchanged or changed in an amount per share (subject to the provision
for adjustment hereinafter set forth) equal to 10,000 times the aggregate amount
of stock,  securities,  cash and/or any other property (payable in kind), as the
case may be,  into which or for which  each share of Common  Stock is changed or
exchanged.  In the  event the  Corporation  shall at any time  after the  Rights
Declaration  Date (i) declare any dividend on Common Stock  payable in shares of
Common Stock, (ii) subdivide the outstanding  Common Stock, or (iii) combine the
outstanding Common Stock into a smaller number of shares, then in each such case
the amount set forth in the  preceding  sentence with respect to the exchange or
change  of  shares of Series A Junior  Participating  Preferred  Stock  shall be
adjusted by multiplying  such amount by a fraction the numerator of which is the
number of shares of Common Stock  outstanding  immediately  after such event and
the  denominator  of which is the  number of shares  of Common  Stock  that were
outstanding immediately prior to such event.


                                      8

<PAGE>



      Section 8.        No Redemption.  The shares of Series A Junior
Participating Preferred Stock shall not be redeemable.

      Section 9.  Ranking.  The Series A Junior  Participating  Preferred  Stock
shall rank junior to all other series of the Corporation's Preferred Stock as to
the payment of dividends and the distribution of assets, unless the terms of any
such series shall provide otherwise.

      Section 10. Amendment. The Certificate of Incorporation of the Corporation
shall not be further  amended  in any manner  which  would  materially  alter or
change  the  powers,  preferences  or  special  rights  of the  Series  A Junior
Participating  Preferred  Stock  so as to  affect  them  adversely  without  the
affirmative  vote of the  holders of  two-thirds  of the  outstanding  shares of
Series A Junior Participating  Preferred Stock, voting separately as a class; it
being understood that nothing in this Section 10 shall be deemed to restrict the
Corporation from designating  additional shares of Series A Junior Participating
Preferred Stock if the Board of Directors  determines that it is necessary to do
so in order to achieve the purposes of the Rights  Agreement,  dated as of March
31, 1998 between the Corporation and American Stock Transfer & Trust Company.

      Section 11. Fractional  Shares.  Series A Junior  Participating  Preferred
Stock may be issued in fractions of a share which shall entitled the holder,  in
proportion to such holders fractional shares, to exercise voting rights, receive
dividends,  participate  in  distributions  and to have the benefit of all other
rights of holders of Series A Junior Participating Preferred Stock.

      IN WITNESS  WHEREOF,  Bio-Reference  Laboratories,  Inc.  has caused  this
Certificate of Amendment to the Certificate of Incorporation to be duly executed
this day of March 31, 1998.

                                    BIO-REFERENCE LABORATORIES, INC.



                                 By /s/Marc D. Grodman
                                   -------------------
                                    Marc D. Grodman, President



Attest:



/s/Sam Singer
Sam Singer, Secretary

                                      9





                                 Exhibit 10.1

                           FOURTH AMENDMENT TO LEASE

      THIS FOURTH  AMENDMENT  TO LEASE made as of this 9th day of October  1998,
(hereinafter   referred  to  as  this   "Amendment"),   between  ALFRED  SANZARI
ENTERPRISES,  L.P., having an office c/o Alfred Sanzari Enterprises, Court Plaza
North,  25 Main Street,  6th Floor,  Hackensack,  new Jersey 07601  (hereinafter
referred to as "Landlord"),  and BIO-REFERENCE LABORATORIES,  INC., a New Jersey
corporation,  having an office at 481 Edward H. Ross Drive,  Elmwood  Park,  New
Jersey 07407 (hereinafter referred to as "Tenant").
                             W I T N E S S E T H:
      WHEREAS, Alfred Sanzari (Landlord's predecessor-in-interest),  as landlord
(hereinafter  referred  to as  "Sanzari"),  and  Pharmadyne  Laboratories,  Inc.
(Tenant's  predecessor-in-interest),  as  tenant  (hereinafter  referred  to  as
"Pharmadyne"),  heretofore  entered  into a certain  written  Lease  dated as of
November  7, 1978,  wherein and whereby  Landlord  leased to Tenant,  and Tenant
hired from Landlord,  certain premises  consisting of  approximately  thirty-one
thousand five hundred twenty-seven  (31,527) square feet (hereinafter  sometimes
referred  to as the  "Original  Premises"  or the  "Premises"),in  the  building
located at 481 Edward H. Ross Drive,  in the Borough of Elmwood Park,  county of
Bergen and State of New Jersey (hereinafter  referred to as the "Building"),  as
more  particularly  described  therein,  for a term which  commenced on March 1,
1979,  and was  scheduled to expire on February 28, 1989,  at the Basic Rent and
additional  rent,  and upon the terms,  covenants,  conditions,  provisions  and
agreements contained in said Lease; and
      WHEREAS,  said Lease was modified by that certain First Amendment to Lease
dated  November 1, 1979,  wherein and whereby,  inter alia,  Landlord and Tenant
settled certain disputes; and


<PAGE>



      WHEREAS,  said Lease and the interest of Pharmadyne as tenant  thereunder,
was assigned to CL Laboratories of New Jersey, Inc.  (hereinafter referred to as
"CL"),  pursuant to that certain  Assignment and  Assumption of Lease  Agreement
dated December 10, 1981; and
      WHEREAS,  said Lease was further modified by that certain  Agreement dated
as of March  23,  1988,  wherein  and  whereby,  inter  alia,  the Lease and the
interest  of  CL  as  tenant  thereunder,  was  assigned  to  Med-Mobile,   Inc.
(hereinafter  referred  to as  "Med-  Mobile"),  and the term of the  Lease  was
extended for a further period of five (5) years, commencing on March 1 1989, and
expiring on February 28, 1984; and
      WHEREAS,  said Lease was further modified by that Certain Second Amendment
to Lease dated as of March 23, 1988; and
      WHEREAS,  said Lease was  modified by that Third  Amendment to lease dated
January 31, 1992, wherein and whereby,  inter alia,  Landlord and Tenant settled
certain  defaults  by  Tenant  under  the  Lease  and  discontinued   litigation
instituted by Landlord against Tenant in connection therewith; and
      WHEREAS, on or about November 15, 1989, Med-Mobile changed its
name to Tenant; and
      WHEREAS,  said Lease was further  modified by that certain Third Amendment
to Lease dated as of February 28, 1994,  wherein and  whereby,  inter alia,  the
term  of the  Lease  was  extended  for a  further  period  of five  (5)  years,
commencing on March 1, 1994, and expiring on February 28, 1999; and
      WHEREAS,  said  Lease,  as so  modified,  and as the same  may  have  been
otherwise amended and/or modified,  is hereinafter  collectively  referred to as
the "Lease"; and

                                      2

<PAGE>



      WHEREAS,  Landlord and Tenant  desire to further  modify the Lease only in
the respects hereinafter stated.
      NOW THEREFORE,  in  consideration of the premises demised by the Lease and
the mutual  covenants  hereinafter  contained  and for other  good and  valuable
consideration,  the receipt and  adequacy of which is hereby  acknowledged,  the
parties hereto by these presents do covenant and agree as follows:
      1. The  recital  clauses  set forth  above  shall be deemed a part of this
Amendment as though set forth verbatim and at length herein.
      2. Except as otherwise  expressly set forth herein,  all capitalized terms
in this Amendment shall have the meanings set forth for such terms in the Lease.
      3. A. The "Term" of the Lease (as defined in  Paragraph B of Schedule  "C"
attached to the Lease)  shall be deemed to be further  extended  for a period of
vive (5) years,  commencing  March 1, 1999, to and including  February 28, 2004,
inclusive,  upon the terms,  covenants,  conditions,  provisions  and agreements
contained in the Lease, as modified by this Amendment.
            B.  Effective  as of March 1,  1999,  "Basic  Rent" (as  defined  in
Paragraph A of Schedule "C" attached to the Lease) shall be deemed to be the sum
of Two Hundred Twenty Thousand Six Hundred Eighty-Nine and 00/100  ($220,689.00)
Dollars per annum,  payable in equal monthly  installments of Eighteen  Thousand
Three Hundred Ninety and 75/100 ($18,390.75) Dollars each.
      4.    A.    (1)   Effective as of the date Landlord delivers
possession of the "Additional Space" (as hereinafter defined)
(hereinafter referred to as the "Additional Space Commencement
Date"), Landlord hereby leases to Tenant, and Tenant hereby hires
from Landlord, a portion of the building located at 487 Edward H.

                                      3

<PAGE>



Ross Drive,  Borough of Elmwood  Park,  County of Bergen and State of New Jersey
(hereinafter   referred  to  as  the   "Adjacent   Building"),   consisting   of
approximately  twenty-four  thousand  (24,000) square feet, as shown on the plan
attached hereto and made a part hereof as Schedule "A-1"  (hereinafter  referred
to as the "Additional Space").
                  (2) The  "Demised  Premises"  (as  defined in Article 1 of the
Lease) shall be and be deemed to be: "(I) a portion of the Building,  consisting
of approximately  thirty-one thousand five hundred twenty-seven (31, 527) square
feet, as shown on Schedule "A" attached to the Lease;  and (ii) a portion of the
Adjacent  Building,  consisting of approximately  twenty-four  thousand (24,000)
square feet, as shown on Schedule "A-1" attached hereto."
            B.    Effective as of the Additional Space Commencement
Date, the following shall be applicable solely with respect to the
Additional space:
                  (1) "Basic  Rent" (as defined in  Paragraph A of Schedule  "C"
attached to the Lease)  shall be deemed to be the sum of One  Hundred  Fifty-Six
Thousand and 00/100  ($156,000.00)  Dollars per annum,  payable in equal monthly
installments of Thirteen Thousand and 00/100 ($13,000.00) Dollars each.
                  (2)  "Proportionate  Share'  (as  defined  in  Paragraph  E of
Schedule "C" attached to the Lease)  shall be deemed to be  "twenty-five  (25%)(
percent/"
                  (3) The number of parking  spaces  provided in  Paragraph 4 of
the Third  Amendment to Lease dated as of February 28, 1994,  shall be deemed to
be "twenty (20)", a shown on the plan attached  hereto and made a part hereof as
Schedule "A-2."

                                      4

<PAGE>



                  (4) Wherever in the Lease  reference is made to the "Building"
or the "building," same shall be deemed to be the Adjacent Building.
            (C) (1) Tenant has examined and inspected the  Additional  Space and
agrees to accept the same in the condition in which it exists on the  Additional
Space Commencement Date. Tenant hereby acknowledges and agrees that no materials
whatsoever  are to be  furnished  by  Landlord  and no  work  whatever  is to be
performed  by  Landlord in  connection  with said  Additional  Space or any part
thereof.
            (2) (I) Tenant agrees, at Tenant's sole cost and expense, to perform
all work in accordance with plans and  specifications  to be prepared by Tenant,
at Tenant's  sole cost and expense,  and  thereafter,  delivered to Landlord for
Landlord's  approval,   which  approval  shall  not  be  unreasonably   withheld
(hereinafter referred to as "Tenant's Additional Space Work").
                  (ii)  Tenant's  Additional  Space Work shall be  performed  in
accordance  with  all  applicable  laws  and in  good  and  workmanlike  manner,
utilizing  new and  first-class  materials.  Tenant  shall obtain and deliver to
Landlord all  "sign-offs"  and  approvals in  connection  therewith,  including,
without limitation, a certificate of occupance.
                  (iii) (a) Tenant  acknowledges  and agrees that Landlord shall
have the right to submit a bid for the performance of Tenant's  Additional Space
Work.
                              (b)   In the event Tenant selects Landlord
to perform Tenant's  Additional Space Work,  Tenant agrees to pay Landlord,  the
total cost of Tenant's Additional Space work, as follows:  (x) twenty-five (25%)
percent  shall be paid by Tenant  to  Landlord  upon  commencement  of  Tenant's
Additional Space Work, as

                                      5

<PAGE>



additional  rent, upon demand therefor;  (y) twenty-five  (25%) percent shall be
paid by Tenant to Landlord upon completion of Tenant's Additional Space Work, as
additional rent, upon demand therefor; and (z) fifty (50%) percent shall be paid
by Tenant to Landlord,  by increasing  the Basic Rent reserved and covenanted to
be paid by Tenant to Landlord under the Leae, as modified by this Amendment,  by
the annual amount required to fully amortize such amount over sixty (60) months,
plus  interest,  at the rate of ten (10%)  percent  per annum,  in which  event,
Landlord  and Tenant  shall  execute  and  deliver  to each  other an  agreement
modifying  the Lease  (including  this  Amendment),  setting forth the increased
Basic Rent,  but such  increase  shall  nevertheless  be effective  even if such
agreement is not executed and delivered.
                        (iv)  Tenant shall be required to utilize
Landlord or the  contractors  designated  by Landlord  with  respect to any work
which involves penetrating or altering the exterior, facade, floor slab, roof or
structure of the Building  which Tenant  desires to perform in  connection  with
Tenant's  Additional  Space  Work  (or  any  other  work  in and to the  Demised
Premises),  provided  that  the  cost  charged  by  Landlord  or the  contractor
designated  by Landlord is not greater than ten 910%)  percent of the lowest bid
received by Tenant in a competitive bid for the same scope of work. In the event
the cost charged by Landlord or the contractor designated by Landlord is greater
than ten (10%) percent of the lowest bid received by Tenant as  aforesaid,  then
Tenant shall be entitled to retain its own  contractors  to perform  which work,
subject to the prior written  approval of Landlord,  which approval shall not be
unreasonably withheld or delayed.
                  (3)   (I)   Landlord shall be liable and responsible
for the costs of compliance with any environmental laws [including,

                                      6

<PAGE>



without limitation,  the Industrial Site Recovery Act, N.J.S.A. 13:1k-6 ET SEQ.,
and the regulations promulgated thereunder (hereinafter collectively referred to
as "ISRA")] for spills or  discharges of  "hazardous  substances"  or "hazardous
wastes" (as such terms are defined under such environmental laws) which occurred
in or to the Additional  Space prior to the Additional  Space Term  Commencement
Date and which  were not  caused in whole or in part,  by Tenant or its  agents,
servants, employees, contractors or representatives.
                        (ii)  Landlord shall indemnify and hold Tenant
harmless from and against any and all claims and liabilities (including, but not
limited  to,  reasonable  attorneys'  fees)  which may be  incurred by Tenant in
connection  with,  or arising out of  Landlord's  obligations  contained  in (I)
hereof.
      5.    Effective as of the date hereof:
            A.    Article 40 of the Lease shall be deemed to be
deleted, and the following inserted in its place:
      "40.  RENEWAL OPTION:
            ---------------
            A. Subject to the provisions set forth below,  Tenant shall have the
            option to renew this Lease for an additional  term of five (5) years
            (hereinafter  referred to as the "Renewal Term"), which Renewal Term
            shall  commence  upon  the  expiration  of the  term of  this  Lease
            (hereinafter  referred to as the "Initial Term").  All of the terms,
            covenants  and  conditions  of this Lease  shall  govern the Renewal
            Term,  except as otherwise  specifically set forth hereinafter or if
            APPLICABLE thereto:

                        (1) The Annual  Basic Rent shall be the  greater of: (I)
            the "Market Rent" (as defined in subsection (2) hereof); or (ii) the
            Basic Rent and  additional  rent which was in effect during the last
            year of the Initial Term.

                        (2) "Market Rent" shall mean the
            fair market rent for the Premises for the
            Renewal Term, determined as of the date one

                                      7

<PAGE>



            hundred  eighty  (180) days prior to the  expiration  of the Initial
            Term (hereinafter  referred to as the "Determination  Date"),  based
            upon the rents  generally  in effect  for  comparable  condition  in
            Bergen  County,  New  Jersey.  Market  Rent  (for  the  purposes  of
            determining the Basic Rent only during the commonly known as a "net"
            basis;  that is, in  computing  Market Rent it shall be assumed that
            all real estate taxes and customary  services are excluded from such
            Basic Rent.

                        (3) Landlord shall notify Tenant  (hereinafter  referred
            to as "Landlord's Determination Notice") of Landlord's Determination
            Notice") of Landlord's determination of the Market Rent within sixty
            (60)  days of the  Determination  Date.  If  Tenant  disagrees  with
            Landlord's determination,  Tenant shall notify Landlord (hereinafter
            referred to as "Tenant's Notice of Disagreement") within thirty (30)
            days of receipt of Landlord's Determination Notice. Time shall be of
            the essence with respect to Tenant's Notice of Disagreement, and the
            failure of Tenant to give such  notice  within  the time  period set
            forth above shall  conclusively be deemed an acceptance by Tenant of
            the Market Rent as  determined by Landlord and a waiver by Tenant of
            any right to dispute  such Market Rent.  If Tenant  timely gives its
            Tenant's  Notice of  disagreement,  then the  Market  Rent  shall be
            determined as follows:  Landlord and Tenant shall, within thirty (30
            days of the date on which Tenant's Notice of Disagreement was given,
            each appoint "Appraiser" (as hereinafter defined) for the purpose of
            determining the Market Rent. An "Appraiser" shall mean either: (1) a
            duly qualified  impartial  real estate  appraiser who is a member of
            the  American  Institute  of Real Estate  Appraisers  and who has at
            least ten (1) years  experience  in  appraising  the rental value of
            industrial/warehouse  properties  comparable  to  the  Building  and
            located in Northern New Jersey;  or (ii) a New Jersey  licensed real
            estate broker for a period in excess of ten (1) years and who has at
            least ten 91) years experience in leasing industrial/warehouse space
            in  buildings  comparable  to the  Building  located in Northern New
            Jersey.  In the event that the two 92)  Appraisers so appointed fail
            to agree ass to the Market  Rent  within a period of thirty (3) days
            after  the  appointment  of  the  second  Appraiser,  such  two  92)
            Appraisers shall forthwith  appoint a third Appraiser who shall make
            a determination  in the manner  hereinafter  described within thirty
            93) days thereafter.

                                      8

<PAGE>



            If such two (2) Appraisers  fail to agree upon such third  Appraiser
            within ten (1) days  following the last thirty 93) day period,  such
            third Appraiser  shall be appointed by the Bergen County  Assignment
            Judge of the New Jersey Superior  Court.  Such two (2) Appraisers or
            the third  Appraiser,  as the case may be,  shall  proceed  with all
            reasonable  dispatch to determine  the Market Rent.  Within  fifteen
            915) days  following the  appointment of the third  Appraiser,  each
            party shall submit to the third  Appraiser a written  report setting
            forth its  determination  of the  market  Rent,  together  with such
            information  on comparable  rentals,  or such other evidence as such
            party shall deem relevant.  The third Appraiser shall, within thirty
            (30) days  following the  submission of such written  reports render
            its decision by selecting the determination of Market Rent submitted
            by  either  the  Appraiser  selected  by  Landlord  or the  Appraise
            selected by Tenant which,  in the judgement of the third  Appraiser,
            most nearly  reflects  the Market Rent.  It is expressly  understood
            that such third Appraiser shall have no power or authority to select
            any Market Rent other than a Market Rent  submitted by the Appraiser
            selected by Landlord or the  Appraiser  selected by Tenant,  and the
            decision of such third Appraiser shall be final and binding upon the
            parties hereto.  The decision of such Appraisers shall be final, and
            such  decision  shall be in writing  and a copy  shall be  delivered
            simultaneously to Landlord and to Tenant. If such Appraisers fail to
            deliver their decision as set forth above prior to the  commencement
            of the Renewal Term,  Tenant shall pay Landlord the Basic Rent which
            was in effect as of the last day of the  Initial  Term,  until  such
            decision is so delivered.  If the Market Rent as determined above is
            in excess of the actual rent paid, then Tenant,  upon demand,  shall
            pay to Landlord the difference  between the actual rent paid and the
            Market Rent from the commencement of the Renewal Term.  Landlord and
            Tenant  shall each be  responsible  for and shall pay the fee of the
            Appraiser  appointed by them  respectively,  and Landlord and Tenant
            shall share equally the fee of the third Appraiser.

                  B.    Tenant's option to renew, as
            provided in subparagraph A hereof, shall be
            conditioned upon and subject to each of the
            following:

                        (1)  Tenant  shall  notify  Landlord  in  writing of its
            exercise of its option to renew at least  twelve (12) months but not
            more than

                                      9

<PAGE>



            fifteen (15) months prior to the expiration of
            the Initial Term;

                        (2) At the time  Landlord  receives  Tenant's  notice as
            provided in  subsection  91) hereof and at the  commencement  of the
            Renewal Term:  (I) Tenant shall not be in default under the terms of
            provisions of this Lease;  and (ii) Tenant shall not have  subleased
            fifty (50%) percent or more of the Premises,  exclusive of subleases
            to any parent, subsidiary or affiliate of Tenant;

                        (3) Tenant  shall have no further  renewal  option other
            than the option to renew this Lease for the one (1) Renewal  Term as
            set forth in subparagraph A hereof;

                        (4) This  option to renew  shall be deemed  personal  to
            Tenant and may not be assigned or transferred,  except in connection
            with an assignment  effectuated in accordance with the provisions of
            Article 12 hereof; and

                        (5) Landlord  shall have no obligation to do any work or
            perform  any  services  for the  Renewal  Term with  respect  to the
            premises,  which  Tenant  agrees  to  accept  in its  then  "as  is"
            condition)"

            B.    The following paragraphs shall be deemed to be

added to the Lease as Articles 41 through 44 thereof:

            "41.  NO  MONEY  DAMAGES:  If in  this  Lease  it is  provided  that
            Landlord's  consent  or  approval  as to  any  matter  will  not  be
            unreasonably  withheld,  and it is  established  by a court  or body
            having  final   jurisdiction  there  over  that  Landlord  has  been
            unreasonable,  then  Landlord  shall be  deemed  to have  given  its
            consent or approval  and, in  addition  thereto,  shall be liable to
            Tenant for money damages [excluding,  however, consequential damages
            (e.g.,  lost profits or loss of business)] by reason of  withholding
            its  consent,  if such court or body  specifically  determined  that
            landlord has acted in bad faith or maliciously  (the burden of which
            shall be  Landlord's  responsibility  to prove that landlord has not
            acted  in bad  fair or  maliciously),  subject  nevertheless  to the
            provisions of Article 36 hereof."

            "42.  HOLDING OVER:     If Tenant retains
                  ------------
            possession of the Premises or any part
            thereof, after the termination of the term by
            lapse of time or otherwise, without prior
            written approval of Landlord, Tenant shall pay

                                      10

<PAGE>



            Landlord,  two 92) times the  monthly  Basic Rent  payable by Tenant
            during the last full  month of the term,  together  with  additional
            rent and other charges as provided herein,  for the time Tenant thus
            remains in possession,  and, in addition thereto, shall pay Landlord
            all damages, consequential as well as direct, sustained by reason of
            Tenant's retention of possession. If Tenant remains in possession of
            the Premises or any part thereof,  after the termination of the term
            by lapse of time or  otherwise,  such  holding  over  shall,  at the
            election of Landlord expressed in a written notice to Tenant and not
            otherwise, constitute an extension of this lease on a month-to-month
            basis,  at two (2) times the  monthly  Basic Rent  payable by Tenant
            during the lat full month of the term, together with additional rent
            and other charges as provided herein.  The provision of this Article
            do not  exclude  Landlord  rights of  re-entry  or any  other  right
            hereunder."

            "43.  RIGHT OF FIRST OFFER:
                  --------------------

                  A. So long as: (I) Tenant is not in default  under this Lease;
            (ii) this Lease is in full force and  effect;  and (iii)  Tenant and
            any parent,  subsidiary  or  affiliate  of Tenant is  occupying  the
            entire  Premises for the purpose of conducting  its  business,  then
            Landlord  agrees that,  in the event any space in Elmwood  Corporate
            Park which is then owned by Landlord  (hereinafter called the "Offer
            Space"),  shall  become  "available  for  leasing"  (as  hereinafter
            define),  at any time and from time to time  after the  commencement
            date of this Lease, before offering to lease such Offer Space to any
            third party,  Landlord  will first offer to Tenant in writing  (such
            offer by Landlord to Tenant  being  hereinafter  called  "Landlord's
            Offer") the right to include such Offer Space within the Premises as
            of the date specified by Landlord in Landlord's  Offer  (hereinafter
            called the "Availability  Date"). The Availability Date shall be the
            date that the Offer Space which is the subject of  Landlord's  offer
            is reasonably  expected to become  available  for leasing.  Landlord
            shall specify in Landlord's  Offer,  the terms and  conditions  upon
            which  Landlord  is  willing  to lease  such  Offer  Space to Tenant
            (hereinafter  collectively  called "Landlord's  Terms"),  including,
            without limitation:

                        (1)   the Availability Date of such
            Offer Space;


                                      11

<PAGE>



                        (2)   the amount of square footage
            contained in such Offer Space;

                        (3)   Tenant's Proportionate Share;

                        (4)   the amount of Basic Rent and
            additional rent;

                        (5)   the term of the leasing of such
            Offer Space which may be for period longer
            than the Term);

                        (6)   the location and configuration
            of such Offer Space; and

                        (7) such other terms and conditions  upon which Landlord
            is willing to lease the Offer Space to Tenant.

                  B. Tenant shall have the right to accept Landlord's Offer with
            respect  to  such  Offer  Space  within   fifteen  (15)  days  after
            Landlord's  Offer.  Time  shall be of the  essence  with  respect to
            Tenant's acceptance of Landlord's Offer. If Tenant does not duly and
            timely accept  Landlord's Offer with respect to the Offer Space: (I)
            landlord shall be under no further obligation to Tenant with respect
            thereto,  and Landlord  may then lease the Offer Space  contained in
            Landlord's  Offer (or any part or parts thereof) to others,  on such
            terms  and  conditions  (including  rent  and  additional  rent)  as
            Landlord then elects in its sole discretion.

                  C.    if Tenant duly and timely accepts
            Landlord's Offer, such Offer Space shall be
            added to the Premises on Landlord's Terms, and
            upon the following further terms and
            conditions, effective as of the Availability
            Date:

                        (1) Landlord  shall have no obligation to do any work or
            perform any services  with respect to the Offer Space,  which Tenant
            agrees to accept in its then "as is" condition;

                        (2)   the Premises shall be the space
            originally demised by this Lease, plus the
            Offer Space; and

                        (3) any other  changes which are required to reflect the
            addition  of such Offer Space  shall be  appropriately  made to this
            Lease.

                  D.    Except as expressly set forth
            hereinabove, the leasing of such Offer Space

                                      12

<PAGE>



            shall be subject to and in  accordance  with all of the other terms,
            covenants and provisions of this Lease.

                  E. Notwithstanding the foregoing, the Offer Space shall not be
            "available  for  leasing,"  if: (I) the Offer  Space is subject to a
            right or option or a renewal right or option  contained in any other
            lease  entered into by Landlord  prior to the date hereof;  or (ii))
            the Offers  Space  remains  occupied by the tenant to whom the Offer
            Space is  presently  leased  (whether  by  renewal or  extension  or
            otherwise), or is offered for re-letting to a subtenant or assignees
            of such present  tenant;  or (iii) if another party desires to lease
            more  space in  Elmwood  Corporate  Park than  Tenant,  which  space
            includes the Offer space.

                  F.    The right of first offer set forth
            in this Article, is personal to Tenant named
            herein and may not be assigned or transferred.

                  G. Upon request of Landlord,  Tenant shall execute and deliver
            an agreement  setting forth the terms and condition sunder which any
            such Offer Space is added to the premises;  it being  understood and
            agreed  that  such  terms  and  conditions  shall   nevertheless  be
            effective   regardless  if  such   agreement  is  not  executed  and
            delivered.

                  H.  Tenant  acknowledges  and agrees  that  landlord  shall be
            obligated  to make  Landlord's  Offer to Tenant only at such time as
            each Offer Space initially becomes "available for leasing;" it being
            understood and agreed by Tenant,  the right of first offer contained
            herein is a one 91) time  right  only  with  respect  to each  Offer
            Space."

            "44.  TENANT'S RIGHT OF SELF-HELP:
                  ---------------------------

                  A. If  Landlord  fails  to make  any  repairs  or do any  work
            required  of  Landlord  solely  with  respect  to  the  roof  of the
            Building,  in accordance  with the  provisions of this Leae, and any
            such  failure  continues  for period of five 95) days  after  notice
            thereof is given by Tenant to Landlord,  or, if such failure require
            more than ten (10) days to cure in the  exercise  of due  diligence,
            unless  Landlord  commences  to cure same  within  said ten (10) day
            period an d thereafter  diligently prosecute the same to completion,
            then Tenant, in addition to such other rights and remedies as may be
            available to Tenant  hereunder,  may, but shall not be obligated to,
            make such repairs or perform such work in accordance

                                      13

<PAGE>



            with the provision of this Lease, at Tenants
            sole cost and expense.

                  B. In the event  Tenant  makes such  repairs or performs  such
            work, Tenant shall use only those  contractors  utilized by Landlord
            in the Building for such work unless such  contractors are unwilling
            or unable to perform  such work,  in which event  Tenant may utilize
            the services of any other  qualified  contractor  which normally and
            regularly  performs  similar  work  in  comparable  building  in the
            vicinity of the Building, and provided that: (I) any such contractor
            does not void or limit any warranty or guaranty procured by Landlord
            regarding  the  roof;  (ii)  such  work is  performed  by  Tenant in
            accordance  with the  provision  of this  Leae;  and  (iii))  Tenant
            indemnifies and holds Landlord harmless from and against any and all
            claims,  damages and losses  incurred  by  Landlord  an/or any other
            tenant or occupant in the Building as a result of the making of such
            repairs or the performance of such work."

            C.    The address "90 West Franklin Street, Hackensack,
new Jersey, 07601" contained in Article 28 of the lease, shall be
deemed to be deleted, and the address "c/o Alfred Sanzari
Enterprises, P.O. Box 2187, South Hackensack, New Jersey 07606-
2187, with a copy to Cole, Schotz, Meisel, Forman and Leonard,
P.A., Court Plaza North, 25 Main Street, P.O. Box 800, Hackensack,
New Jersey 07602-0800, Attention: Edward M. Schotz, Esq." inserted
in its place.
            D. The  following  shall be  deemed to be  inserted  after the third
sentence  in Article  12 of the  Lease;  "In the event  Landlord  withholds  its
consent to the subletting or assignment as provided herein, Landlord agrees that
it will so notify  Tenant in writing  within the  aforesaid ten (10) day period,
specifying  therein,  in reasonable detail, the reason(s) for the withholding of
such consent."
      6.    A.    Tenant understands and agrees that: (I) the remises
contiguous to the Original Premises, consisting of approximately

                                      14

<PAGE>



thirty-one  thousand seven hundred  forty-four  (31,74) square feet (hereinafter
referred to as the "Contiguous  Space"), is currently leased to, and occupied by
CTX Termination, inc. (hereinafter referred to as "CTX"); and (ii) CTX exercised
its  option to renew the term of its lease  which  now  expires  March 21,  2004
(hereinafter referred to as the "CTX Lease").
            B. So long as (I)  Tenant  is not in  default  under the  Lease,  as
modified by this Amendment; (ii) the Lease, as modified by this Amendment, is in
full force and effect; and (iii) Tenant is occupying the entire Premises for the
purpose of conducing its business,  then,  provided Tenant, at its sole cost and
expense,  secures  the early  termination  of the CTX Lease,  or CTX vacates the
Contiguous  Space or the CTX Lease is terminated  prior to the expiration of the
term  thereof,  landlord  shall  give  Tenant  the  right to  relocate  from the
Additional  Space to the  Contiguous  Space,  upon not less than six (6) months'
prior written  notice given at any time prior to February 29, 2000  (hereinafter
referred to as the "Relocation Notice").

            C. In the  event  Tenant  duly  and  timely  exercise  the  right to
relocate as provided  herein,  the Contiguous Space shall be substituted for the
Additional  Space as of the effective date of such  relocation,  upon all of the
terms, covenants, conditions,  provisions and agreements contained in the Lease,
as modified by this Amendment, except that:

                  (1) "Basic  Rent" (on a per square  foot per annum  basis) and
additional  rent  shall be deemed to be the  amounts  then  payable to Tenant to
Landlord with respect to the Original Premises;

                                      15

<PAGE>



                  (2)   "Proportionate Share" shall be deemed to be
"one hundred (100%) percent";
                  (3) The number of parking  spaces  provided in  Paragraph 4 of
the Third  Amendment to Lease dated as of February 28, 1994,  shall be deemed to
be "thirty-six (36)";
                  (4)   The reference to "Adjacent Building" shall be
deemed to be deleted;
                  (5) At the time Landlord  receives the  Relocation  Notice and
upon the effective date of such relocation, Tenant shall not be in default under
this Lease;
                  (6)  Tenant  pays  to   Landlord,   simultaneously   with  the
Relocation  Notice,  a sum equal to four (4) months'  Basic Rent and  additional
rent then  payable by Tenant to  landlord  under the Lease,  as modified by this
Amendment,  as consideration  fro Tenant's  exercise of its right to relocate to
the Contiguous Space;
                  (7)  Tenant  provides   Landlord,   simultaneously   with  the
Relocation Notice, any documents which evidence the early termination of the CTX
Lease, if applicable; and
                  (8) Tenant shall be liable and  responsible  for restoring the
Contiguous Space to the condition which existed as of the effective date of such
relocation.
            D. In the event  Tenant does not duly and timely  exercise the right
to relocate as provided  herein,  the provisions of this Paragraph shall be null
and void and of no  further  force or effect  and  Tenant  shall have no further
right to relocate to the Contiguous Space.

            E. The right to relocate as provided  herein,  is personal to Tenant
named herein and may not be assigned or transferred.


                                      16

<PAGE>



            F. Upon  request of Landlord,  Tenant  shall  execute and deliver an
agreement  setting  forth the terms and  conditions  under which the  Contiguous
Space is substituted for the Additional  Space;  it being  understood and agreed
that such terms and conditions  shall  nevertheless  be effective  regardless if
such agreement is not executed and delivered.

      7.  Notwithstanding  anything to the contrary  contained herein,  Landlord
hereby approves the following work which may be performed by Tenant, at its sole
cost and expense,  subject  nevertheless  to all of the other terms,  covenants,
conditions,  provisions  and  agreements  of the  Lease,  as  modified  by  this
Amendment (including, without limitation, article 22 thereof):

            A. the conversion of approximately five thousand (5,000) square feet
of warehouse  space currently  existing in the Original  Premises as of the date
hereof, to space to be utilized for production; and

            B. the conversion of approximately  eleven thousand  (11,000) square
feet of warehouse  space currently  existing gin the Additional  Space as of the
dat hereof, to office space.

      8. Tenant  hereby  affirms that  security in the amount of One Hundred Two
thousand four Hundred Sixty-Two and 72/100 ($102,462.72)  Dollars has heretofore
been deposited by Tenant to Landlord under the lease.
      9. Tenant hereby represents and warrants to Landlord,  that Tenant has not
dealt with any real estate  agent or broker in  connection  with this  Amendment
and/or the  Additional  Space,  that this  Amendment  was not  brought  about or
procured through the use or instrumentality of any agent or broker, and that all
negotiations with respect to the term of this Amendment were conducted between

                                      17

<PAGE>



landlord,  and Tenant.  Tenant hereby covenants and agrees to indemnify and hold
Landlord  harmless from and against any and all claims for commissions and other
compensation  made by any agent or agents  and/or any broker or brokers based on
any dealings  between  Tenant and any agent or agents  and/or broker or brokers,
together  with all costs and  expenses  incurred by Landlord in  resisting  such
claim s(including, without limitation, attorney's fees and disbursements).

      10. A. Except as expressly  modified by this Amendment,  the Lease and all
the terms, covenants, conditions,  provisions and agreements thereof, are hereby
in all respects, ratified, confirmed and approved.

            B. Tenant hereby  affirms that, as of the date hereof,  no breach or
default  by  Landlord  has  occurred,  and that the Lease and all of its  terms,
covenants,  conditions,  provisions and  agreements,  except as modified by this
Amendment, are in full force and effect, with no defenses or offsets thereto.

            C. Tenant  hereby  releases  Landlord  of and from all  liabilities,
claims  controversies,  causes of action an other matters of every nature which,
through  the date  hereof,  have or might  have  arisen  out of or in any way in
connection with the Lease and/or the Demised Premises.
      11. This Amendment and the Lease contain the entire understanding  between
the parties with respect to the matters contained  herein.  No  representations,
warranties,  covenants or agreements  have been made concerning or affecting the
subject matter of this amendment, except as are expressly contained herein.
      12. This Amendment may not be changed orally,  but only by an agreement in
writing  by  the  party  against  whom   enforcement  of  any  waiver,   change,
modification or discharge is sought.

                                      18

<PAGE>



      13. This  Amendment  shall be binding upon, an enure to the benefit of the
parties hereto, their respective legal representatives,  successors, and, except
as  otherwise  provided  I the  Lease,  as  modified  by  his  amendment,  their
respective assigns.
      14. The  submission of this  Amendment to Tenant shall not be construed as
an offer, nor shall Tenant have any rights with respect hereto, unless and until
Landlord shall execute a copy of this Amendment an  unconditionally  deliver the
same to Tenant.
      15.  Tenant  hereby  represents  and  warrants to landlord  that:  (I) the
execution, performance and delivery by Tenant of this Amendment does not violate
any  provisions  of its  Charter  or By- Laws,  and has been  fully and  validly
authorized  and approved by any required  corporate  action of Tenant;  (ii) the
obligations  of Tenant  under this  Amendment  are  legal,  valid,  binding  and
enforceable  against Tenant in accordance with its terms;  and (iii)) the person
executing  this  Amendment has the authority to so execute,  perform and deliver
this Amendment on behalf of Tenant.
      16.  Tenant  hereby  acknowledges  and agrees that this  Amendment  is the
result of extensive  negotiations  between the parties.  This Amendment shall be
construed without regard to any presumption or other rule requiring construction
against the party causing this Amendment to be drafted or prepared.
      17.  A  determination  that  any  provision  of  this  Amendment  is  void
unenforceable or invalid shall not affect the  enforceability of validity of any
other provision,  and any determination that the application of any provision of
this  Amendment  to any  person or to  particular  circumstance  sis  illegal or
unenforceable  shall not affect the enforceability or validity of such provision
as it may apply to other person or circumstances.

                                      19

<PAGE>



      18. This  Amendment may be executed in one or more  counterparts,  each of
which,  when so executed and  delivered,  shall be deemed  original,  but all of
which taken together shall constitute but one and the same instrument.
      19. The validity,  performance  and enforcement of this Amendment shall be
governed  by and  construed  in  accordance  with the  laws of the  State of new
Jersey.
      IN WITNESS  WHEREOF,  the parties hereto have  respectively  executed this
Fourth Amendment to Lease as of the day and year first written above.

Witness for Landlord:                     ALFRED SANZARI ENTERPRISES,
                                          L.P.

                                          By:   Alfred Sanzari
                                                Enterprises, Inc., its
                                                General Partner


                                          By:
- -------------------------------
                                          Name: David Sanzari
                                          Title: President

Attest for Tenant:                        BIO-REFERENCE LABORATORIES,
                                          INC.

By:                                       By:
   ----------------------------
Name:                                     Name:
      ------------------------
Title:              Secretary             Title:              President
       -------------                             -------------

                                      20






                                 Exhibit 10.2
                             EMPLOYMENT AGREEMENT


      This  Employment  Agreement  dated  as of the  1st day of  November,  1997
between  Bio-Reference  Laboratories,  Inc., a New Jersey  corporation  with its
principal  place of  business  at 481 Edward H. Ross Drive,  Elmwood  Park,  New
Jersey 07407 (the  "Company") and Marc Grodman,  residing at RD 1, P.O. Box 309,
Califon, New Jersey 07830 (the "Employee").
                             W I T N E S S E T H :

      WHEREAS,  the Company is primarily  engaged in the operation of a clinical
laboratory in northern New Jersey, and

      WHEREAS,  the Company desires to avail itself of the Employee's  knowledge
and experience  and to employ the Employee as its President and Chief  Executive
Officer on the terms and conditions hereinafter set forth, and
      WHEREAS,  the  Employee  desires to be so  employed  by the Company on the
terms and conditions hereinafter set forth.
      NOW, THEREFORE, in consideration of the mutual covenants herein contained,
the parties agree as follows:
      1. Terms of  Employment.  The Company agrees to employ the Employee as its
President and Chief Executive  Officer,  or in such other position of comparable
status and  responsibility  as the Company  may from time to time direct  and/or
desire, and the Employee agrees to accept such employment with the Company,  for
a  term  commencing  as of  November  1,  1997  (the  "Commencement  Date")  and
continuing  until  October  31,  2004 (the  "Expiration  Date"),  unless  sooner
terminated as provided in this Agreement (the "Employment  Period").  As used in
this Agreement,  the term "Employment Period" shall also include any periods for
which this Agreement is renewed pursuant to Section 2 hereof.


<PAGE>



      2. Renewal. This Agreement shall be automatically renewable for additional
three year periods;  provided, that either the Company or the Employee may elect
not to renew this  Agreement upon written notice to the other party no less than
three (3) months before the Expiration Date or any subsequent  extension thereof
pursuant to this Section 2.
      3.    Duties.
            ------
            (a) During the  Employment  Period,  the Employee shall perform such
duties and exercise such powers relating to the Company as are commensurate with
the office of President  and Chief  Executive  Officer and shall have such other
duties and powers as the Board of  Directors  shall from time to time  assign to
him, including by way of example but not limitation,  duties with respect to any
of the  Company's  associated  companies.  As used in this  Agreement,  the term
"Associated  Companies"  shall mean any company (i) of which not less than fifty
(50%)  percent of the equity is  beneficially  owned by the  Company or (ii) any
subsidiary of such company, if any.
            (b) During the Employment Period, the Employee shall devote at least
90% of his working time during  normal  business  hours and his best efforts and
ability to the business of the Company,  shall faithfully and diligently perform
the duties of his employment with the Company and shall do all reasonably in his
power to promote, develop and extend the business of the Company.
            (c) During the Employment  period, the Employee shall not, except as
a representative  of the Company or with the written consent of the Company,  be
directly or  indirectly  engaged,  concerned or interested in the conduct of any
other business competing or likely to compete with the Company;  provided,  that
notwithstanding anything contained in this Agreement to the

                                      2

<PAGE>



contrary,  the Employee shall not be precluded from devoting a reasonable amount
of his time to:

            (i)  serving  with the prior  written  approval  of the Company as a
            director or member of a committee of any  organization  involving no
            conflict of interest with the business of the Company; and

            (ii)  managing  his  personal  investments;   provided,   that  such
            activities  shall  not  materially  interfere  with  the  Employee's
            performance of his duties hereunder; and

            (iii)  participating  in such courses of  instruction  and rendering
            such services as shall be  consistent  with the  maintenance  of his
            skills as a medical doctor; and

            (iv) performance as an Assistant  Professor of Clinical Medicine and
            assistant   attending   physician  at  Columbia  University  and  at
            Presbyterian Hospital,  respectively,  or the performance of similar
            services at any similar institutions; and

            (v) rendering  medical  services to the Uniform  Firefighters of New
            York City similar to the services presently rendered by the Employee
            pursuant to a contract presently in force.

            (d) The  Employee  shall be  employed  at the offices of the Company
located in Elmwood Park, New Jersey; provided that the Employee acknowledges and
agrees that the proper  performance  of these  duties may make it  necessary  to
spend reasonable periods of time in other parts of the country.
      4.    Compensation.
            (a) During the Employment Period, the Company shall pay the Employee
as  compensation  for his services under this  Agreement,  a minimum annual Base
Compensation  consisting  of salary and bonus in the  aggregate  amount of Three
Hundred Ninety Five Thousand ($395,000) Dollars (the "Base  Compensation").  The
Base Compensation  shall be payable in equal installments in accordance with the
regular payroll procedures established by the Company. In October of each fiscal
year  during the  Employment  Period,  the  Company's  Board of  Directors  will
consider increasing the Employee's Compensation under this Agreement, based upon
the performance of

                                      3

<PAGE>



the  Company  and of the  Employee  during the fiscal year then ending with such
increase, if granted, taking effect as of the immediately following November 1.
            (b) The  Company  shall pay for  (excluding  the P.S.  58 costs) and
maintain  "Split  Dollar"  Life  Insurance  in the face  amount of Four  Million
($4,000,000)  Dollars  (including  Two  Million  ($2,000,000)  Dollars  of  such
insurance which it presently maintains),  insuring the life of the Employee. The
proceeds  of such  insurance  shall be  payable  to the  estate of the  Employee
(excluding  benefits  required to be paid to the  Company  pursuant to the split
dollar plan for the premiums paid).
            (c) The Company shall lease and insure,  under the Company's policy,
an automobile for the benefit of the Employee.  The Company shall be responsible
for  maintenance,  gasoline,  repair  and all other  such  costs but only to the
extent such expenses relate to business use of the automobile. At the end of the
lease term, or in the event of the termination of this Agreement for any reason,
including non-renewal, the Employee shall have the following options:
            (i) surrender the automobile to the Company,
            (ii) assume the Company's lease payment obligation; or
            (iii) exercise the purchase option of the lease, if any.

           (d) The Company  shall  promptly  pay or  reimburse  the  Employee
for all expenses  incurred by the Employee in the  performance  of his duties
under this Agreement.  Such  expenses  shall be  limited  to the  reasonable
out-of-pocket  expenses necessarily and actually incurred by the Employee in the
performance of his duties;  provided that (i) the expenses have been detailed on
a form acceptable to the Company and submitted to the Company for review

                                      4

<PAGE>



and approval and (ii) appropriate supporting documentation is submitted together
with the approved expense form.
            (e) The  Employee  shall be  entitled to  participate  in any fringe
benefit and bonus plans  available to the Company's  employees as in effect from
time to time, to the extent that the Employee may be eligible to do so under the
applicable provisions of the plans including but not limited to pension,  profit
sharing,  stock option and similar plans and life and medical insurance plans or
coverage maintained by the Company for senior personnel and/or all personnel.
            (f) The Employee shall be entitled to such  vacation,  personal time
and holidays as he is eligible for under the Company's  Employment and Personnel
Policy as the same presently exists or may hereinafter be amended.
            (g)  Notwithstanding  the  provisions  of  subparagraph  (a) of this
Section 4, the Employee  shall also be entitled to a percentage  increase in his
Base Compensation as in effect on June 30 of each year that this Agreement is in
effect, equal to the percentage increase in the Consumer Price Index - All Items
for the New York  metropolitan  area (or any successor  index) for such month of
June as  compared  to such  Consumer  Price  Index  for the month of June in the
immediately  preceding  year.  Any  such  increase  shall  be  effective  on the
immediately  following November 1. No adjustments shall be made for decreases in
such Index.
      5.    Issuances of Stock and Options. In further consideration
            ------------------------------
for his employment, the Company agreed on May 13, 1997 to the
following issuances of its Common Stock and options to the
Employee.
            (a)  Forfeitable  Stock -- The Company has issued  300,000 shares of
its Common Stock to the Employee subject to forefiture.

                                      5

<PAGE>



If the Employee's  employment agreement is terminated by the Company "For Cause"
or at the Employee's option,  without "Good Reason" (but not due to a "Change in
Control"),  all as herein defined,  the Employee will forfeit such shares on the
following basis.

If Termination "For
Cause" or "Without Good
Reason" Occurs during the                            Number of Shares
   Following Periods                                      Forfeited
- --------------------                                 --------------
May 1, 1997 through April 30, 1998                    225,000 shs.
May 1, 1998 through April 30, 1999                    150,000 shs.
May 1, 1999 through April 30, 2000                     75,000 shs.
            (b) Stock  Options -- The  Company  has issued  five-year  incentive
stock options ("ISOs) to the Employee  exercisable to purchase 100,000 shares of
the Common Stock at $.790625 per share.  These ISOs are subject to the terms and
conditions of the Company's 1989 Employees' Stock Option Plan. In addition,  the
Company has issued  ten-year  non-qualified  options  ("NQOs")  to the  Employee
exercisable to purchase 200,000 shares of its Common Stock at $.71875 per share.
The  NQOs to the  extent  not  exercised  shall  terminate  if  this  employment
agreement is terminated by the Company "For Cause" or at the  Employee's  option
without "Good Reason" (but not due to a "Change in Control").
      6. Disability. If during the Employment Period, the Employee shall incur a
Total Disability then,  subject to the earlier  termination of this Agreement or
the earlier  termination  of the  disability,  the Company shall  compensate the
Employee as provided in subparagraphs (a), (b), (c) and (d) of this Section 6.
            (a) For the month in which the Employee incurs the total disability,
and for the following  twelve (12) months of the  disability,  the Company shall
compensate the Employee at a rate equal to his then current Base Compensation.

                                      6

<PAGE>



            (b) For a period of three (3) months commencing upon the termination
of the period described in subparagraph  (a), the Company shall not pay Employee
any portion of his Base Compensation and Employee shall be on an unpaid leave of
absence.
            (c) If the Employee's  disability  shall terminate at any time prior
to the expiration of the period described in subparagraph (b) of this Section 6,
then the Employee  shall return to full and active  employment  with the Company
under  the  terms of this  Agreement;  provided  that if he shall  again  become
disabled  within a period  of three  (3)  months  after  such  return,  and such
disability  is related to his original  disability,  then the Employee  shall be
deemed to have been continuously disabled from the date he incurred his original
disability.
            (d) Upon  expiration  of the  three (3) month  period  described  in
subparagraph  (b) of this  Section  6,  the  employment  of the  Employee  shall
terminate,  unless an additional leave of absence is granted by the Company,  in
which event the employment of the Employee  shall  terminate upon the expiration
of the additional leave of absence.
            (e) In the event the Employee shall incur a Partial  Disability then
during the period of the Partial  Disability,  the Employee's Base  Compensation
shall be equitably  adjusted  according to the time that he is able to devote to
the affairs of the Company.
            (f) In addition to the foregoing,  the Employee shall be entitled to
receive  the  amounts,  if  any,  as may be  payable  to  him by  reason  of his
disability under policies of insurance maintained by the Company.

            (g) As used in this Agreement,  the term "Total Disability" shall
mean a disability such that, for physical or

                                      7

<PAGE>



mental reasons, the Employee is unable to perform any of his usual duties to the
Company on a  full-time  basis.  As used in this  Agreement,  the term  "Partial
Disability" shall mean a disability,  other than a total  disability,  such that
for  physical or mental  reasons,  the  Employee is unable to perform all of his
usual duties to the Company on a full-time basis.
      7.    Termination.
            (a) Termination by Death. If the Employee dies during the Employment
Period,  the Company's  obligations under this Agreement shall terminate six (6)
months  after the date of death and the  Employee's  estate shall be entitled to
all arrearages of Base  Compensation and expenses.  In addition,  the Employee's
estate (or such other named  beneficiary)  shall be entitled to the amounts,  if
any,  as may be  payable  to his  estate  or  beneficiaries  under  policies  of
insurance maintained by the Company.
            (b)  Termination  for  Cause.  This  Agreement  and  the  Employee's
employment  with  the  Company  may be  terminated  for  Cause  at any  time  in
accordance with  subparagraph (d) of this Section 7. In the event this Agreement
is terminated  for Cause,  the Employee  shall be entitled to all  arrearages of
Base  Compensation and expenses through the Date of Termination but shall not be
entitled  to  further  compensation.  As  used in this  Agreement,  and  without
limitation, the term "Cause" shall mean:
            (i) an act or acts of dishonesty  constituting  criminal acts by the
Employee  resulting or intended to result  directly or  indirectly in gain to or
personal enrichment of the Employee at the Company's expense;

            (ii) the  commission of any crime  involving  fraud,  embezzlement
 or theft by the Employee against the Company;

                                      8

<PAGE>



            (iii) engaging in competition  with the Company,  including taking a
management  position with, or control of, a business engaged in the manufacture,
sale or distribution of a class of products or service which  constituted 15% or
more of the sales or gross  income of the Company and its  associated  companies
during the fiscal year of the Company  immediately  preceding the termination of
the Employee's employment.
            (c)  Termination  at the Option of the Employee.  This Agreement and
the Employee's employment with the Company may be terminated at any time, at the
election of the Employee, for Good Reason in accordance with subparagraph (d) of
this Section 7. In the event this Agreement is terminated  for Good Reason,  the
Employee shall be paid during the remainder of the Employment  Period  (computed
without  giving  effect  to  the  earlier  termination   hereunder),   his  Base
Compensation  (other than due to Partial Disability) at the rate in effect as of
the Date of Termination,  and shall continue to be entitled to employee benefits
as if he were still employed by the Company, until completion of such Employment
Period (computed without giving effect to the earlier termination hereunder). As
used in this  Agreement,  and without  limitation,  the term "Good Reason" shall
mean:
            (i) the assignment to the Employee of duties  inconsistent  with the
office of  President  and Chief  Executive  Officer  of the  Company or his then
current  office,  the removal of the  Employee  from such office or  substantial
reduction   in  the   nature   or  status  of  the   Employee's   then   current
responsibilities;

            (ii) the reduction of the Employee's then current Base  Compensation
(other than due to Partial Disability) ;

            (iii) the relocation of the Company's principal executive offices to
a location more than fifty (50) miles from the Company's

                                      9

<PAGE>



current  principal  executive offices or the transfer of the Employee to a place
other than the Company's  principal executive offices (excepting required travel
on the Company's  business in a manner  substantially  similar to the Employee's
then current business travel obligations); and
            (iv) the failure by the Company to continue to provide the  Employee
with  benefits at least as  favorable  as those in which the  Employee  was then
participating.
            (d)  Notice  of  Termination.   Any  purported  termination  of  the
Employee's  employment  shall be communicated by a written notice of termination
to the other party  hereto and specify the Date of  Termination  (the "Notice of
Termination").  Such notice shall  indicate a specific  terminated  provision in
this Agreement which is relied upon, recite the facts and circumstances  claimed
to provide the basis for such  termination  and specify the Date of Termination.
As used in this Agreement,  the term "Date of  Termination"  shall mean the date
specified in the Notice of Termination, which date shall not be less than thirty
(30) nor more than sixty (60) days from the date the  Notice of  Termination  is
given.  If within  thirty (30) days from the date the Notice of  Termination  is
given,  the party  receiving such notice notifies the other party that a dispute
exists concerning such termination, the Date of Termination shall be the date on
which the dispute is finally resolved. The Date of Termination shall be extended
by a notice of dispute  only if such notice is given in good faith and the party
giving such notice  pursues  the  resolution  of such  dispute  with  reasonable
diligence.  Notwithstanding  the pendency of any such dispute,  the Company will
continue to pay the Employee his full Base Compensation in effect as of the date
of the Notice of  Termination  and continue the Employee as a participant in all
compensation, benefit and

                                      10

<PAGE>



insurance plans in which he was participating at such date, until the dispute is
finally  resolved.  Amounts paid under this  subparagraph (d) are in addition to
all other amounts due under this  Agreement  and shall not be offset  against or
reduce any other amounts due under this Agreement.
      8. Change in Control. In the event of a Change in Control and, as a result
of such  Change in Control,  the  Employee is  terminated  without  Cause or the
Employee  elects to terminate his employment for any reason as a result thereof,
then the Employee shall receive the following benefits:
            (a) The Company shall pay to the Employee his full Base Compensation
at the rate in effect at the time of the Notice of Termination  through the Date
of Termination.
            (b) In lieu of any further  Base  Compensation  payments for periods
subsequent to the Date of Termination,  the Company shall pay to the Employee as
severance pay not later than the fifth day following the Date of Termination,  a
lump sum payment (the  "Severance  Payment")  equal to 2.99 times the average of
the annual  Compensation  which was  payable to the  Employee by the Company and
includible in the  Employee's  gross income for federal  income tax purposes for
the five (5) calendar  years, or for the portion of such period during which the
Employee was actually  employed by the Company if the Employee has been employed
by the Company for less than five (5) calendar  years  preceding  the earlier of
the calendar year in which a Change in Control  occurred or the calendar year of
the Date of Termination (the "Base Period"). Such average shall be determined in
accordance with the provisions of Section  280G(d) of the Internal  Revenue Code
of  1986  as  amended  (the  "Code").  As  used  in  this  Agreement,  the  term
"Compensation"  shall  mean and  include  every  type  and form of  compensation
includible in the Employee's

                                      11

<PAGE>



gross income in respect of his employment by the Company including  compensation
income  recognized  as a result of the exercise of stock  options or sale of the
stock so acquired,  except to the extent otherwise  provided in Congressional or
Joint Committee Reports or temporary or final regulations  interpreting  Section
280G(d) of the Code.
            (c) The  Severance  Payment  shall be  reduced  by the amount of any
other  payment or the value of any  benefit  received  or to be  received by the
Employee in connection with the termination of his employment or contingent upon
a Change in Control  (whether  payable  pursuant to the terms of this Agreement,
any other  plan,  agreement  or  arrangement  with the  Company)  unless (i) the
Employee shall have effectively  waived his receipt or enjoyment of such payment
or benefit  prior to the date of payment of the Severance  Payment,  (ii) in the
opinion of tax counsel  selected by the  Company  such other  payment or benefit
does not  constitute  a  "parachute  payment"  within  the  meaning  of  Section
280G(b)(2)  of the  Code,  or (iii) in the  opinion  of such  tax  counsel,  the
Severance Payment (in its full amount or as partially  reduced,  as the case may
be) plus all other payments or benefits which  constitute  "parachute  payments"
within the meaning of Section 280G(b)(2) of the Code are reasonable compensation
file services actually rendered, within the meaning of Section 280G(b)(4) of the
Code, and such payments are deductible by the Company. The value of any non-cash
benefit or any  deferred  cash  payment  shall be  determined  by the Company in
accordance with the principles of Section 280G(d)(3) and (4) of the Code.
            (d)  Except to the  extent  that  Congressional  or Joint  Committee
Reports or temporary or final regulations  interpreting Section 280G of the Code
specify that such payments would result,

                                      12

<PAGE>



under subsection (c) above, in a reduction in the Severance Payment:

            (i) The Company shall pay to the Employee,  not later than the fifth
day following the Date of Termination, a lump sum amount equal to the sum of (x)
any bonus  compensation  which has been  allocated  or awarded for a fiscal year
preceding the Date of Termination  but has not yet been paid, and (y) a pro rata
portion of any bonus  compensation  which the Employee has earned for the fiscal
year in which the Date of  Termination  occurs  determined  by  multiplying  the
Employee's prior years' bonus  compensation by a fraction equal to the number of
full calendar  months in the fiscal year prior to the Date of  Termination  over
twelve.
            (ii) The Company shall also pay all legal fees and expenses incurred
by the  Employee as a result of such  termination  (including  all such fees and
expenses, if any, incurred in contesting or disputing any such termination or in
seeking to obtain or enforce any right or benefit provided by this Agreement).
            (e) If it is  established  pursuant  to a final  determination  of a
court or an Internal Revenue Service proceeding that,  notwithstanding  the good
faith of the  Employee  and the Company in applying the terms of this Section 8,
the aggregate  "parachute  payments"  paid are in an amount that would result in
any portion of such "parachute  payments" not being deductible by the Company by
reason of Section 280G of the Code,  then the Employee  shall have an obligation
to pay the Company  upon demand an amount equal to the sum of (i) the portion of
the aggregate  "parachute  payments" paid that would not be deductible by reason
of Section 280G of the Code and (ii)  interest on the amount set forth in clause
(i) of this sentence at the applicable Federal rate (as

                                      13

<PAGE>



defined in Section  1274(d) of the Code) from the date of receipt of such excess
until the date of such payment.
            (f) As used in the  Agreement,  the term  "Change in Control"  shall
mean a change in control of a nature  that would be  required  to be reported in
response  to Item  6(e) of  Schedule  14A of  Regulation  14A  issued  under the
Securities Exchange Act of 1934, as amended (the "Exchange Act") as in effect as
of the date  hereof  (regardless  of whether or not a Proxy  Statement  is being
filed pursuant to such Regulation at such time), or if Item 6(e) is no longer in
effect,  any subsequent  regulation  issued under the Exchange Act for a similar
purpose,  whether or not the Company is subject to such reporting  requirements;
provided,  that without limitation,  such a change in control shall be deemed to
have occurred if:
            (i)  any  "person"  other  than  the  Employee  is  or  becomes  the
"beneficial  owner" (as defined in Rule 13d-3 under the Exchange Act),  directly
or  indirectly,  of  securities of the Company  representing  25% or more of the
combined voting power of the Company's then outstanding securities;
            (ii) during any period of two  consecutive  years (not including any
period prior to the date of the Agreement),  individuals who at the beginning of
such period  constitute  the Board of  Directors,  and any new  director,  whose
election by the Board or nomination  for election by the Company's  stockholders
was approved by a vote of at least  two-thirds  of the  directors  then still in
office  who  either  were  directors  at the  beginning  of the  period or whose
election or  nomination  for elections was  previously  approved,  cease for any
reason to constitute a majority of the Board; or

                                      14

<PAGE>



            (iii) the  business  of the  Company is  disposed  of by the Company
pursuant to a liquidation, sale of assets of the Company, or otherwise.
      9. Confidential  Information.  The Employee  acknowledges an obligation of
confidentiality  to the Company and shall not divulge,  disclose or  communicate
any trade  secret,  private or  confidential  information  or other  proprietary
knowledge of the Company or its associated companies obtained or acquired by him
while so employed.  This  restriction  shall apply after the  termination of the
Employee's employment without limit in point of time but shall cease to apply to
information  or  knowledge  which  may come  into  the  public  domain  or whose
disclosure  may be  required  by law or court  order or  pursuant to the written
consent of the Corporation.
      10. Return of Information.  Upon  termination of employment,  the Employee
agrees to not take with him and to deliver to the  Company all  records,  notes,
data, memoranda,  models,  equipment,  blueprints,  drawings,  manuals, letters,
reports and all other materials of a secret or  confidential  nature relating to
the business of the Company which are in possession or control of the Employee.
      11.   General Provisions.
            (a) This  Agreement  contains  the entire  transaction  between  the
parties,  and  there are no other  representations,  warranties,  conditions  or
agreements relating to the subject matter of this Agreement.
            (b)  The  waiver  by any  party  of any  breach  or  default  of any
provision of this Agreement shall not operate or be construed as a waiver of any
subsequent breach.
            (c)  This  Agreement  may  not be  changed  orally  but  only  by an
Agreement in writing duly executed on behalf of the party

                                      15

<PAGE>



against  which  enforcement  of any  waiver,  change,  modification,  consent or
discharge is sought.
            (d) This Agreement shall be binding upon and be enforceable  against
the  Company  and  its  successors  and  assigns.  Insofar  as the  Employee  is
concerned, this Agreement is personal and cannot be assigned.
            (e) This Agreement may be executed in one or more counterparts, each
of which shall be deemed an original, but all of which together shall constitute
one and the same instrument.
            (f) This Agreement shall be construed  pursuant to and in accordance
with the laws of the State of New Jersey.
            (g) If any term or provision of this  Agreement is held or deemed to
be  invalid  or  unenforceable,  in whole or in  part,  by a court of  competent
jurisdiction,  this  Agreement  shall  be  ineffective  to the  extent  of  such
invalidity or  unenforceability  without  rendering invalid or unenforceable the
remaining terms and provisions of this Agreement.
            (h) Any  dispute,  grievance  or  controversy  arising  under  or in
connection  with this  Agreement  shall be referred to the Board of Directors of
the  Company  and  shall  be  dealt  with  by  personal  discussion,  and if not
satisfactorily  resolved,  shall be submitted to arbitration  under the Rules of
the American Arbitration Association in New York City.
            (i) Any consent of the Company  required under this Agreement  shall
not be unreasonably withheld or delayed.



                                      16

<PAGE>



      IN WITNESS  WHEREOF,  the parties have executed this Agreement on the date
first above written.
                                    COMPANY:

                                    Bio-Reference Laboratories, Inc.



                                    By /s/Howard Dubinett
                                      Its Executive Vice President
                                      Duly Authorized


                                    EMPLOYEE:



                                    /s/Marc Grodman
                                    Marc Grodman





                                      17





                                 Exhibit 10.3
                             EMPLOYMENT AGREEMENT


      This  Employment  Agreement  dated as of the 1st day of May,  1997 between
Bio-Reference  Laboratories,  Inc., a New Jersey  corporation with its principal
place of business at 481 Edward H. Ross Drive,  Elmwood  Park,  New Jersey 07407
(the "Company") and Howard  Dubinett,  residing at 195 Little Falls Road,  Cedar
Grove, New Jersey 07009 (the "Employee").
                             W I T N E S S E T H :
      WHEREAS, the Company is primarily engaged in the operation of
a clinical laboratory in northern New Jersey, and
      WHEREAS,  the Company desires to avail itself of the Employee's  knowledge
and  experience  and to employ the Employee as its Executive  Vice President and
Chief Operating Officer on the terms and conditions hereinafter set forth, and
      WHEREAS,  the  Employee  desires to be so  employed  by the Company on the
terms and conditions hereinafter set forth.
      NOW, THEREFORE, in consideration of the mutual covenants herein contained,
the parties agree as follows:
      1. Terms of  Employment.  The Company agrees to employ the Employee as its
Executive Vice President and Chief Operating Officer,  or in such other position
of  comparable  status and  responsibility  as the Company may from time to time
direct and/or desire, and the Employee agrees to accept such employment with the
Company,  for a term commencing as of May 1, 1997 (the "Commencement  Date") and
continuing  until  October  31,  2002 (the  "Expiration  Date"),  unless  sooner
terminated as provided in this Agreement (the


<PAGE>



"Employment  Period").  As used in this Agreement,  the term "Employment Period"
shall also include any periods for which this  Agreement is renewed  pursuant to
Section 2 hereof.
      2. Renewal. This Agreement shall be automatically renewable for additional
one year  periods;  provided,  that either the Company or the Employee may elect
not to renew this  Agreement upon written notice to the other party no less than
one (1) month before the  Expiration  Date or any subsequent  extension  thereof
pursuant to this Section 2.
      3.    Duties.
            ------
            (a) During the  Employment  Period,  the Employee shall perform such
duties and exercise such powers relating to the Company as are commensurate with
the office of Executive  Vice  President and Chief  Operating  Officer and shall
have such other duties and powers as the Board of  Directors  shall from time to
time assign to him, including by way of example but not limitation,  duties with
respect to any of the Company's associated companies. As used in this Agreement,
the term  "Associated  Companies"  shall mean any  company (i) of which not less
than fifty (50%) percent of the equity is  beneficially  owned by the Company or
(ii) any subsidiary of such company, if any.
            (b) During the Employment  Period,  the Employee shall devote all of
his working time during normal  business  hours and his best efforts and ability
to the business of the Company,  shall  faithfully  and  diligently  perform the
duties of his employment with

                                      2

<PAGE>



the Company and shall do all reasonably in his power to promote,
develop and extend the business of the Company.
            (c) During the Employment  period, the Employee shall not, except as
a representative  of the Company or with the written consent of the Company,  be
directly or  indirectly  engaged,  concerned or interested in the conduct of any
other business competing or likely to compete with the Company;  provided,  that
notwithstanding  anything  contained  in this  Agreement  to the  contrary,  the
Employee  shall not be precluded  from devoting a reasonable  amount of his time
to:
            (i)  serving  with the prior  written  approval  of the Company as a
            director or member of a committee of any  organization  involving no
            conflict of interest with the business of the Company; and

            (ii)  managing  his  personal  investments;   provided,   that  such
            activities  shall  not  materially  interfere  with  the  Employee's
            performance of his duties hereunder.

            (d) The  Employee  shall be  employed  at the offices of the Company
located in Elmwood Park, New Jersey; provided that the Employee acknowledges and
agrees that the proper  performance  of these  duties may make it  necessary  to
spend reasonable periods of time in other parts of the country.
      4.    Compensation.
            (a) During the Employment Period, the Company shall pay the Employee
as  compensation  for  his  services  under  this  Agreement,   a  minimum  Base
Compensation  at an annual rate of One Hundred  Ninety One Thousand Four Hundred
($191,400)  Dollars  through  October 31, 1997,  and thereafter a minimum annual
Base Compensation consisting

                                      3

<PAGE>



of salary  and bonus in the  aggregate  amount of Two  Hundred  Twenty  Thousand
($220,000)  Dollars (the "Base  Compensation").  The Base Compensation  shall be
payable in equal  installments in accordance with the regular payroll procedures
established by the Company. In October of each fiscal year during the Employment
Period, the Company's Board of Directors will consider increasing the Employee's
Compensation under this Agreement, based upon the performance of the Company and
of the  Employee  during the fiscal  year then  ending  with such  increase,  if
granted, taking effect as of the immediately following November 1.
            (b) The  Company  shall pay for  (excluding  the P.S.  58 costs) and
maintain  "Split Dollar" Life Insurance in the face amount of Five Hundred Fifty
Thousand ($550,000) Dollars,  insuring the life of the Employee. The proceeds of
such  insurance  shall be  payable  to the  estate  of the  Employee  (excluding
benefits  required to be paid to the Company  pursuant to the split  dollar plan
for the premiums  paid).  Once such  insurance  is fully paid,  the Company will
apply for an additional aggregate Five Hundred Fifty Thousand ($550,000) Dollars
of similar "Split Dollar" Life Insurance  insuring the Employee's  life and will
maintain such additional insurance during his employment by the Company.
            (c) The Company shall lease and insure,  under the Company's policy,
an automobile for the benefit of the Employee.  The Company shall be responsible
for  maintenance,  gasoline,  repair  and all other  such  costs but only to the
extent such expenses relate to business use of the automobile. At the end of the
lease

                                      4

<PAGE>



term,  or in the event of the  termination  of this  Agreement  for any  reason,
including non-renewal, the Employee shall have the following options:
            (i) surrender the automobile to the Company,
            (ii) assume the Company's lease payment obligation; or
            (iii) exercise the purchase option of the lease, if any.
            (d)   The Company shall promptly pay or reimburse the
Employee for all expenses  incurred by the  Employee in the  performance  of his
duties under this  Agreement.  Such expenses  shall be limited to the reasonable
out-of-pocket  expenses necessarily and actually incurred by the Employee in the
performance of his duties;  provided that (i) the expenses have been detailed on
a form  acceptable  to the Company and  submitted  to the Company for review and
approval and (ii) appropriate  supporting  documentation  is submitted  together
with the approved expense form.
            (e) The  Employee  shall be  entitled to  participate  in any fringe
benefit and bonus plans  available to the Company's  employees as in effect from
time to time, to the extent that the Employee may be eligible to do so under the
applicable provisions of the plans including but not limited to pension,  profit
sharing,  stock option and similar plans and life and medical insurance plans or
coverage maintained by the Company for senior personnel and/or all personnel.
            (f)   The Employee shall be entitled to such vacation,
personal time and holidays as he is eligible for under the

                                      5

<PAGE>



Company's  Employment and Personnel  Policy as the same presently  exists or may
hereinafter be amended.
            (g)  Notwithstanding  the  provisions  of  subparagraph  (a) of this
Section 4, the Employee  shall also be entitled to a percentage  increase in his
Base Compensation as in effect on June 30 of each year that this Agreement is in
effect, equal to the percentage increase in the Consumer Price Index - All Items
for the New York  metropolitan  area (or any successor  index) for such month of
June as  compared  to such  Consumer  Price  Index  for the month of June in the
immediately  preceding  year.  Any  such  increase  shall  be  effective  on the
immediately  following November 1. No adjustments shall be made for decreases in
such Index.
      5.    Issuances of Stock and Options. In further consideration
            ------------------------------
for his employment, the Company agreed on May 13, 1997 to the
following issuances of its Common Stock and options to the
Employee.
            (a)  Forfeitable  Stock -- The Company has issued  240,000 shares of
its Common  Stock to the  Employee  subject  to  forfeiture.  If the  Employee's
employment  agreement  is  terminated  by  the  Company  "For  Cause"  or at the
Employee's option, without "Good Reason" (but not due to a "Change in Control"),
all as herein  defined,  the Employee  will forfeit such shares on the following
basis.  If  Termination  "For Cause" or "Without Good Reason"  Occurs during the
Number of Shares Following  Periods Forfeited May 1, 1997 through April 30, 1998
180,000 shs. May 1, 1998 through April 30, 1999 120,000 shs. May 1, 1999 through
April 30, 2000 60,000 shs.

                                      6

<PAGE>



            (b) Stock Options -- The Company has issued ten-year incentive stock
options  ("ISOs") to the Employee  exercisable to purchase  60,000 shares of its
Common  Stock at  $.71875  per share.  These  ISOs are  subject to the terms and
conditions of the Company's 1989 Employees' Stock Option Plan.
      6. Disability. If during the Employment Period, the Employee shall incur a
Total Disability then,  subject to the earlier  termination of this Agreement or
the earlier  termination  of the  disability,  the Company shall  compensate the
Employee as provided in subparagraphs (a), (b), (c) and (d) of this Section 6.
            (a) For the month in which the Employee incurs the total disability,
and for the following  twelve (12) months of the  disability,  the Company shall
compensate the Employee at a rate equal to his then current Base Compensation.
            (b) For a period of three (3) months commencing upon the termination
of the period described in subparagraph  (a), the Company shall not pay Employee
any portion of his Base Compensation and Employee shall be on an unpaid leave of
absence.
            (c) If the Employee's  disability  shall terminate at any time prior
to the expiration of the period described in subparagraph (b) of this Section 6,
then the Employee  shall return to full and active  employment  with the Company
under  the  terms of this  Agreement;  provided  that if he shall  again  become
disabled  within a period  of three  (3)  months  after  such  return,  and such
disability is related to his original disability, then the Employee

                                      7

<PAGE>



shall be deemed to have been continuously disabled from the date he incurred his
original disability.
            (d) Upon  expiration  of the  three (3) month  period  described  in
subparagraph  (b) of this  Section  6,  the  employment  of the  Employee  shall
terminate,  unless an additional leave of absence is granted by the Company,  in
which event the employment of the Employee  shall  terminate upon the expiration
of the additional leave of absence.
            (e) In the event the Employee shall incur a Partial  Disability then
during the period of the Partial  Disability,  the Employee's Base  Compensation
shall be equitably  adjusted  according to the time that he is able to devote to
the affairs of the Company.
            (f) In addition to the foregoing,  the Employee shall be entitled to
receive  the  amounts,  if  any,  as may be  payable  to  him by  reason  of his
disability under policies of insurance maintained by the Company.
            (g) As used in this  Agreement,  the term "Total  Disability"  shall
mean a disability  such that,  for physical or mental  reasons,  the Employee is
unable to perform any of his usual  duties to the Company on a full-time  basis.
As  used  in  this  Agreement,  the  term  "Partial  Disability"  shall  mean  a
disability,  other than a total  disability,  such that for  physical  or mental
reasons,  the  Employee  is unable  to  perform  all of his usual  duties to the
Company on a full-time basis.
      7.    Termination.

                                      8

<PAGE>



            (a) Termination by Death. If the Employee dies during the Employment
Period,  the Company's  obligations under this Agreement shall terminate six (6)
months  after the date of death and the  Employee's  estate shall be entitled to
all arrearages of Base  Compensation and expenses.  In addition,  the Employee's
estate (or such other named  beneficiary)  shall be entitled to the amounts,  if
any,  as may be  payable  to his  estate  or  beneficiaries  under  policies  of
insurance maintained by the Company.
            (b)  Termination  for  Cause.  This  Agreement  and  the  Employee's
employment  with  the  Company  may be  terminated  for  Cause  at any  time  in
accordance with  subparagraph (d) of this Section 7. In the event this Agreement
is terminated  for Cause,  the Employee  shall be entitled to all  arrearages of
Base  Compensation and expenses through the Date of Termination but shall not be
entitled  to  further  compensation.  As  used in this  Agreement,  and  without
limitation, the term "Cause" shall mean:
            (i) an act or acts of dishonesty  constituting  criminal acts by the
Employee  resulting or intended to result  directly or  indirectly in gain to or
personal enrichment of the Employee at the Company's expense;
            (ii)  the commission of any crime involving fraud,
embezzlement or theft by the Employee against the Company;
            (iii) engaging in competition  with the Company,  including taking a
management  position with, or control of, a business engaged in the manufacture,
sale or distribution of a class of products or service which  constituted 15% or
more of the sales or

                                      9

<PAGE>



gross income of the Company and its associated  companies during the fiscal year
of  the  Company  immediately   preceding  the  termination  of  the  Employee's
employment.
            (c)  Termination  at the Option of the Employee.  This Agreement and
the Employee's employment with the Company may be terminated at any time, at the
election of the Employee, for Good Reason in accordance with subparagraph (d) of
this Section 7. In the event this Agreement is terminated  for Good Reason,  the
Employee shall be paid during the remainder of the Employment  Period  (computed
without  giving  effect  to  the  earlier  termination   hereunder),   his  Base
Compensation  (other than due to Partial Disability) at the rate in effect as of
the Date of Termination,  and shall continue to be entitled to employee benefits
as if he were still employed by the Company, until completion of such Employment
Period (computed without giving effect to the earlier termination hereunder). As
used in this  Agreement,  and without  limitation,  the term "Good Reason" shall
mean:
            (i) the assignment to the Employee of duties  inconsistent  with the
office of Executive Vice President and Chief Operating Officer of the Company or
his then  current  office,  the  removal  of the  Employee  from such  office or
substantial  reduction  in the nature or status of the  Employee's  then current
responsibilities;
            (ii) the reduction of the Employee's then current Base
Compensation (other than due to Partial Disability) ;
            (iii) the relocation of the Company's principal executive offices to
a location more than fifty (50) miles from the Company's

                                      10

<PAGE>



current  principal  executive offices or the transfer of the Employee to a place
other than the Company's  principal executive offices (excepting required travel
on the Company's  business in a manner  substantially  similar to the Employee's
then current business travel obligations); and
            (iv) the failure by the Company to continue to provide the  Employee
with  benefits at least as  favorable  as those in which the  Employee  was then
participating.
            (d)  Notice  of  Termination.   Any  purported  termination  of  the
Employee's  employment  shall be communicated by a written notice of termination
to the other party  hereto and specify the Date of  Termination  (the "Notice of
Termination").  Such notice shall  indicate a specific  terminated  provision in
this Agreement which is relied upon, recite the facts and circumstances  claimed
to provide the basis for such  termination  and specify the Date of Termination.
As used in this Agreement,  the term "Date of  Termination"  shall mean the date
specified in the Notice of Termination, which date shall not be less than thirty
(30) nor more than sixty (60) days from the date the  Notice of  Termination  is
given.  If within  thirty (30) days from the date the Notice of  Termination  is
given,  the party  receiving such notice notifies the other party that a dispute
exists concerning such termination, the Date of Termination shall be the date on
which the dispute is finally resolved. The Date of Termination shall be extended
by a notice of dispute  only if such notice is given in good faith and the party
giving such notice  pursues  the  resolution  of such  dispute  with  reasonable
diligence.

                                      11

<PAGE>



Notwithstanding  the pendency of any such dispute,  the Company will continue to
pay the  Employee  his full  Base  Compensation  in effect as of the date of the
Notice  of  Termination  and  continue  the  Employee  as a  participant  in all
compensation,  benefit and insurance plans in which he was participating at such
date,  until  the  dispute  is  finally   resolved.   Amounts  paid  under  this
subparagraph  (d) are in addition to all other amounts due under this  Agreement
and shall not be offset  against  or reduce  any other  amounts  due under  this
Agreement.
      8. Change in Control. In the event of a Change in Control and, as a result
of such  Change in Control,  the  Employee is  terminated  without  Cause or the
Employee  elects to terminate his employment for any reason as a result thereof,
then the Employee shall receive the following benefits:
            (a) The Company shall pay to the Employee his full Base Compensation
at the rate in effect at the time of the Notice of Termination  through the Date
of Termination.
            (b) In lieu of any further  Base  Compensation  payments for periods
subsequent to the Date of Termination,  the Company shall pay to the Employee as
severance pay not later than the fifth day following the Date of Termination,  a
lump sum payment (the  "Severance  Payment")  equal to 2.99 times the average of
the annual  Compensation  which was  payable to the  Employee by the Company and
includible in the  Employee's  gross income for federal  income tax purposes for
the five (5) calendar  years, or for the portion of such period during which the
Employee was actually employed by the

                                      12

<PAGE>



Company if the Employee has been  employed by the Company for less than five (5)
calendar  years  preceding the earlier of the calendar year in which a Change in
Control  occurred or the  calendar  year of the Date of  Termination  (the "Base
Period").  Such average shall be determined in accordance with the provisions of
Section 280G(d) of the Internal Revenue Code of 1986 as amended (the "Code"). As
used in this  Agreement,  the term  "Compensation"  shall mean and include every
type and form of  compensation  includible  in the  Employee's  gross  income in
respect  of  his  employment  by  the  Company  including   compensation  income
recognized  as a result of the exercise of stock options or sale of the stock so
acquired,  except to the extent  otherwise  provided in  Congressional  or Joint
Committee Reports or temporary or final regulations interpreting Section 280G(d)
of the Code.
            (c) The  Severance  Payment  shall be  reduced  by the amount of any
other  payment or the value of any  benefit  received  or to be  received by the
Employee in connection with the termination of his employment or contingent upon
a Change in Control  (whether  payable  pursuant to the terms of this Agreement,
any other  plan,  agreement  or  arrangement  with the  Company)  unless (i) the
Employee shall have effectively  waived his receipt or enjoyment of such payment
or benefit  prior to the date of payment of the Severance  Payment,  (ii) in the
opinion of tax counsel  selected by the  Company  such other  payment or benefit
does not  constitute  a  "parachute  payment"  within  the  meaning  of  Section
280G(b)(2)  of the  Code,  or (iii) in the  opinion  of such  tax  counsel,  the
Severance Payment (in its full

                                      13

<PAGE>



amount or as partially  reduced,  as the case may be) plus all other payments or
benefits which  constitute  "parachute  payments"  within the meaning of Section
280G(b)(2)  of the Code  are  reasonable  compensation  file  services  actually
rendered,  within  the  meaning  of  Section  280G(b)(4)  of the Code,  and such
payments are deductible by the Company. The value of any non-cash benefit or any
deferred cash payment shall be determined by the Company in accordance  with the
principles of Section 280G(d)(3) and (4) of the Code.
            (d)  Except to the  extent  that  Congressional  or Joint  Committee
Reports or temporary or final regulations  interpreting Section 280G of the Code
specify that such  payments  would  result,  under  subsection  (c) above,  in a
reduction in the Severance Payment:
            (i) The Company shall pay to the Employee,  not later than the fifth
day following the Date of Termination, a lump sum amount equal to the sum of (x)
any bonus  compensation  which has been  allocated  or awarded for a fiscal year
preceding the Date of Termination  but has not yet been paid, and (y) a pro rata
portion of any bonus  compensation  which the Employee has earned for the fiscal
year in which the Date of  Termination  occurs  determined  by  multiplying  the
Employee's prior years' bonus  compensation by a fraction equal to the number of
full calendar  months in the fiscal year prior to the Date of  Termination  over
twelve.
            (ii) The Company shall also pay all legal fees and expenses incurred
by the  Employee as a result of such  termination  (including  all such fees and
expenses, if any, incurred in

                                      14

<PAGE>



contesting or disputing any such  termination or in seeking to obtain or enforce
any right or benefit provided by this Agreement).
            (e) If it is  established  pursuant  to a final  determination  of a
court or an Internal Revenue Service proceeding that,  notwithstanding  the good
faith of the  Employee  and the Company in applying the terms of this Section 8,
the aggregate  "parachute  payments"  paid are in an amount that would result in
any portion of such "parachute  payments" not being deductible by the Company by
reason of Section 280G of the Code,  then the Employee  shall have an obligation
to pay the Company  upon demand an amount equal to the sum of (i) the portion of
the aggregate  "parachute  payments" paid that would not be deductible by reason
of Section 280G of the Code and (ii)  interest on the amount set forth in clause
(i) of this  sentence  at the  applicable  Federal  rate (as  defined in Section
1274(d) of the Code) from the date of receipt of such  excess  until the date of
such payment.
            (f) As used in the  Agreement,  the term  "Change in Control"  shall
mean a change in control of a nature  that would be  required  to be reported in
response  to Item  6(e) of  Schedule  14A of  Regulation  14A  issued  under the
Securities Exchange Act of 1934, as amended (the "Exchange Act") as in effect as
of the date  hereof  (regardless  of whether or not a Proxy  Statement  is being
filed pursuant to such Regulation at such time), or if Item 6(e) is no longer in
effect,  any subsequent  regulation  issued under the Exchange Act for a similar
purpose,  whether or not the Company is subject to such reporting  requirements;
provided, that without

                                      15

<PAGE>



limitation, such a change in control shall be deemed to have
occurred if:
            (i)  any  "person"  other  than  the  Employee  is  or  becomes  the
"beneficial  owner" (as defined in Rule 13d-3 under the Exchange Act),  directly
or  indirectly,  of  securities of the Company  representing  25% or more of the
combined voting power of the Company's then outstanding securities;
            (ii) during any period of two  consecutive  years (not including any
period prior to the date of the Agreement),  individuals who at the beginning of
such period  constitute  the Board of  Directors,  and any new  director,  whose
election by the Board or nomination  for election by the Company's  stockholders
was approved by a vote of at least  two-thirds  of the  directors  then still in
office  who  either  were  directors  at the  beginning  of the  period or whose
election or  nomination  for elections was  previously  approved,  cease for any
reason to constitute a majority of the Board; or
            (iii) the  business  of the  Company is  disposed  of by the Company
pursuant to a liquidation, sale of assets of the Company, or otherwise.
      9.    Confidential Information. The Employee acknowledges an
            ------------------------
obligation of confidentiality to the Company and shall not divulge,
disclose or communicate any trade secret, private or confidential
information or other proprietary knowledge of the Company or its
associated companies obtained or acquired by him while so employed.
This restriction shall apply after the termination of the

                                      16

<PAGE>



Employee's employment without limit in point of time but shall cease to apply to
information  or  knowledge  which  may come  into  the  public  domain  or whose
disclosure  may be  required  by law or court  order or  pursuant to the written
consent of the Corporation.
      10. Return of Information.  Upon  termination of employment,  the Employee
agrees to not take with him and to deliver to the  Company all  records,  notes,
data, memoranda,  models,  equipment,  blueprints,  drawings,  manuals, letters,
reports and all other materials of a secret or  confidential  nature relating to
the business of the Company which are in possession or control of the Employee.
      11.   General Provisions.
            (a) This  Agreement  contains  the entire  transaction  between  the
parties,  and  there are no other  representations,  warranties,  conditions  or
agreements relating to the subject matter of this Agreement.
            (b)  The  waiver  by any  party  of any  breach  or  default  of any
provision of this Agreement shall not operate or be construed as a waiver of any
subsequent breach.
            (c)  This  Agreement  may  not be  changed  orally  but  only  by an
Agreement  in  writing  duly  executed  on  behalf of the  party  against  which
enforcement of any waiver, change, modification, consent or discharge is sought.
            (d) This Agreement shall be binding upon and be enforceable  against
the Company and its successors and assigns.

                                      17

<PAGE>



Insofar as the Employee is concerned,  this  Agreement is personal and cannot be
assigned.
            (e) This Agreement may be executed in one or more counterparts, each
of which shall be deemed an original, but all of which together shall constitute
one and the same instrument.
            (f) This Agreement shall be construed  pursuant to and in accordance
with the laws of the State of New Jersey.
            (g) If any term or provision of this  Agreement is held or deemed to
be  invalid  or  unenforceable,  in whole or in  part,  by a court of  competent
jurisdiction,  this  Agreement  shall  be  ineffective  to the  extent  of  such
invalidity or  unenforceability  without  rendering invalid or unenforceable the
remaining terms and provisions of this Agreement.
            (h) Any  dispute,  grievance  or  controversy  arising  under  or in
connection  with this  Agreement  shall be referred to the Board of Directors of
the  Company  and  shall  be  dealt  with  by  personal  discussion,  and if not
satisfactorily  resolved,  shall be submitted to arbitration  under the Rules of
the American Arbitration Association in New York City.
            (i) Any consent of the Company  required under this Agreement  shall
not be unreasonably withheld or delayed.





                                      18

<PAGE>



      IN WITNESS  WHEREOF,  the parties have executed this Agreement on the date
first above written.
                                    COMPANY:

                                    Bio-Reference Laboratories, Inc.



                                    By /s/Marc D. Grodman
                                      President
                                      Duly Authorized


                                    EMPLOYEE:



                                    /s/Howard Dubinett
                                    Howard Dubinett





                                      19





                                 Exhibit 10.4
                             EMPLOYMENT AGREEMENT


      This  Employment  Agreement  dated as of the 1st day of May,  1997 between
Bio-Reference  Laboratories,  Inc., a New Jersey  corporation with its principal
place of business at 481 Edward H. Ross Drive,  Elmwood  Park,  New Jersey 07407
(the  "Company")  and Sam Singer,  residing at 10 Heritage  Drive,  Edison,  New
Jersey 08820 (the "Employee").
                             W I T N E S S E T H :
      WHEREAS, the Company is primarily engaged in the operation of
a clinical laboratory in northern New Jersey, and
      WHEREAS,  the Company desires to avail itself of the Employee's  knowledge
and  experience  and to employ  the  Employee  as its Vice  President  and Chief
Financial Officer on the terms and conditions hereinafter set forth, and
      WHEREAS,  the  Employee  desires to be so  employed  by the Company on the
terms and conditions hereinafter set forth.
      NOW, THEREFORE, in consideration of the mutual covenants herein contained,
the parties agree as follows:
      1. Terms of  Employment.  The Company agrees to employ the Employee as its
Vice  President  and Chief  Financial  Officer,  or in such  other  position  of
comparable status and responsibility as the Company may from time to time direct
and/or  desire,  and the  Employee  agrees to accept  such  employment  with the
Company,  for a term commencing as of May 1, 1997 (the "Commencement  Date") and
continuing  until  October  31,  2002 (the  "Expiration  Date"),  unless  sooner
terminated as provided in this Agreement (the "Employment


<PAGE>



Period").  As used in this Agreement,  the term  "Employment  Period" shall also
include any periods for which this  Agreement  is renewed  pursuant to Section 2
hereof.
      2. Renewal. This Agreement shall be automatically renewable for additional
one year  periods;  provided,  that either the Company or the Employee may elect
not to renew this  Agreement upon written notice to the other party no less than
one (1) month before the  Expiration  Date or any subsequent  extension  thereof
pursuant to this Section 2.
      3.    Duties.
            ------
            (a) During the  Employment  Period,  the Employee shall perform such
duties and exercise such powers relating to the Company as are commensurate with
the office of Vice  President  and Chief  Financial  Officer and shall have such
other duties and powers as the Board of Directors shall from time to time assign
to him,  including by way of example but not limitation,  duties with respect to
any of the Company's associated companies.  As used in this Agreement,  the term
"Associated  Companies"  shall mean any company (i) of which not less than fifty
(50%)  percent of the equity is  beneficially  owned by the  Company or (ii) any
subsidiary of such company, if any.
            (b) During the Employment  Period,  the Employee shall devote all of
his working time during normal  business  hours and his best efforts and ability
to the business of the Company,  shall  faithfully  and  diligently  perform the
duties of his employment with

                                      2

<PAGE>



the Company and shall do all reasonably in his power to promote,
develop and extend the business of the Company.
            (c) During the Employment  period, the Employee shall not, except as
a representative  of the Company or with the written consent of the Company,  be
directly or  indirectly  engaged,  concerned or interested in the conduct of any
other business competing or likely to compete with the Company;  provided,  that
notwithstanding  anything  contained  in this  Agreement  to the  contrary,  the
Employee  shall not be precluded  from devoting a reasonable  amount of his time
to:
            (i)  serving  with the prior  written  approval  of the Company as a
            director or member of a committee of any  organization  involving no
            conflict of interest with the business of the Company; and

            (ii)  managing  his  personal  investments;   provided,   that  such
            activities  shall  not  materially  interfere  with  the  Employee's
            performance of his duties hereunder.

            (d) The  Employee  shall be  employed  at the offices of the Company
located in Elmwood Park, New Jersey; provided that the Employee acknowledges and
agrees that the proper  performance  of these  duties may make it  necessary  to
spend reasonable periods of time in other parts of the country.


                                      3

<PAGE>



      4.    Compensation.
            (a) During the Employment Period, the Company shall pay the Employee
as  compensation  for  his  services  under  this  Agreement,   a  minimum  Base
Compensation  at an annual  rate of One Hundred  Ninety  Thousand  Five  Hundred
($190,500)  Dollars  through  October 31, 1997,  and thereafter a minimum annual
Base Compensation  consisting of salary and bonus in the aggregate amount of Two
Hundred Twenty Thousand ($220,000) Dollars (the "Base  Compensation").  The Base
Compensation  shall be  payable in equal  installments  in  accordance  with the
regular payroll procedures established by the Company. In October of each fiscal
year  during the  Employment  Period,  the  Company's  Board of  Directors  will
consider increasing the Employee's Compensation under this Agreement, based upon
the  performance of the Company and of the Employee  during the fiscal year then
ending with such  increase,  if  granted,  taking  effect as of the  immediately
following November 1.
            (b) The  Company  shall pay for  (excluding  the P.S.  58 costs) and
maintain  "Split  Dollar"  Life  Insurance  in the face  amount of Four  Hundred
Thousand ($400,000) Dollars,  insuring the life of the Employee. The proceeds of
such  insurance  shall be  payable  to the  estate  of the  Employee  (excluding
benefits  required to be paid to the Company  pursuant to the split  dollar plan
for the premiums  paid).  Once such  insurance  is fully paid,  the Company will
apply for an additional  aggregate Four Hundred Thousand  ($400,000)  Dollars of
similar "Split Dollar" Life Insurance

                                      4

<PAGE>



insuring the Employee's life and will maintain such additional  insurance during
his employment by the Company.
            (c) The Company shall lease and insure,  under the Company's policy,
an automobile for the benefit of the Employee.  The Company shall be responsible
for  maintenance,  gasoline,  repair  and all other  such  costs but only to the
extent such expenses relate to business use of the automobile. At the end of the
lease term, or in the event of the termination of this Agreement for any reason,
including non-renewal, the Employee shall have the following options:
            (i) surrender the automobile to the Company,
            (ii) assume the Company's lease payment obligation; or
            (iii) exercise the purchase option of the lease, if any.
            (d)   The Company shall promptly pay or reimburse the
Employee for all expenses  incurred by the  Employee in the  performance  of his
duties under this  Agreement.  Such expenses  shall be limited to the reasonable
out-of-pocket  expenses necessarily and actually incurred by the Employee in the
performance of his duties;  provided that (i) the expenses have been detailed on
a form  acceptable  to the Company and  submitted  to the Company for review and
approval and (ii) appropriate  supporting  documentation  is submitted  together
with the approved expense form.
            (e) The  Employee  shall be  entitled to  participate  in any fringe
benefit and bonus plans  available to the Company's  employees as in effect from
time to time, to the extent that the Employee may be eligible to do so under the
applicable provisions of the plans

                                      5

<PAGE>



including but not limited to pension,  profit sharing,  stock option and similar
plans and life and medical insurance plans or coverage maintained by the Company
for senior personnel and/or all personnel.
            (f) The Employee shall be entitled to such  vacation,  personal time
and holidays as he is eligible for under the Company's  Employment and Personnel
Policy as the same presently exists or may hereinafter be amended.
            (g)  Notwithstanding  the  provisions  of  subparagraph  (a) of this
Section 4, the Employee  shall also be entitled to a percentage  increase in his
Base Compensation as in effect on June 30 of each year that this Agreement is in
effect, equal to the percentage increase in the Consumer Price Index - All Items
for the New York  metropolitan  area (or any successor  index) for such month of
June as  compared  to such  Consumer  Price  Index  for the month of June in the
immediately  preceding  year.  Any  such  increase  shall  be  effective  on the
immediately  following November 1. No adjustments shall be made for decreases in
such Index.
      5.    Issuances of Stock and Options. In further consideration
            ------------------------------
for his employment, the Company agreed on May 13, 1997 to the
following issuances of its Common Stock and options to the
Employee.
            (a)  Forfeitable  Stock -- The Company has issued  200,000 shares of
its Common  Stock to the  Employee  subject  to  forefiture.  If the  Employee's
employment  agreement  is  terminated  by  the  Company  "For  Cause"  or at the
Employee's option, without "Good Reason" (but

                                      6

<PAGE>



not due to a "Change in Control"), all as herein defined, the
Employee will forfeit such shares on the following basis.
If Termination "For
Cause" or "Without Good
Reason" Occurs during the                            Number of Shares
   Following Periods                                     Forfeited
- -------------------------                             ------------

May 1, 1997 through April 30, 1998                    150,000 shs.
May 1, 1998 through April 30, 1999                    100,000 shs.
May 1, 1999 through April 30, 2000                     50,000 shs.
            (b) Stock Options -- The Company has issued ten-year incentive stock
options  ("ISOs")to the Employee  exercisable  to purchase  50,000 shares of its
Common  Stock at  $.71875  per share.  These  ISOs are  subject to the terms and
conditions of the Company's 1989 Employees' Stock Option Plan.
      6. Disability. If during the Employment Period, the Employee shall incur a
Total Disability then,  subject to the earlier  termination of this Agreement or
the earlier  termination  of the  disability,  the Company shall  compensate the
Employee as provided in subparagraphs (a), (b), (c) and (d) of this Section 6.
            (a) For the month in which the Employee incurs the total disability,
and for the following  twelve (12) months of the  disability,  the Company shall
compensate the Employee at a rate equal to his then current Base Compensation.
            (b) For a period of three (3) months commencing upon the termination
of the period described in subparagraph  (a), the Company shall not pay Employee
any portion of his Base Compensation and Employee shall be on an unpaid leave of
absence.

                                      7

<PAGE>



            (c) If the Employee's  disability  shall terminate at any time prior
to the expiration of the period described in subparagraph (b) of this Section 6,
then the Employee  shall return to full and active  employment  with the Company
under  the  terms of this  Agreement;  provided  that if he shall  again  become
disabled  within a period  of three  (3)  months  after  such  return,  and such
disability  is related to his original  disability,  then the Employee  shall be
deemed to have been continuously disabled from the date he incurred his original
disability.
            (d) Upon  expiration  of the  three (3) month  period  described  in
subparagraph  (b) of this  Section  6,  the  employment  of the  Employee  shall
terminate,  unless an additional leave of absence is granted by the Company,  in
which event the employment of the Employee  shall  terminate upon the expiration
of the additional leave of absence.
            (e) In the event the Employee shall incur a Partial  Disability then
during the period of the Partial  Disability,  the Employee's Base  Compensation
shall be equitably  adjusted  according to the time that he is able to devote to
the affairs of the Company.
            (f) In addition to the foregoing,  the Employee shall be entitled to
receive  the  amounts,  if  any,  as may be  payable  to  him by  reason  of his
disability under policies of insurance maintained by the Company.
            (g)   As used in this Agreement, the term "Total
Disability" shall mean a disability such that, for physical or

                                      8

<PAGE>



mental reasons, the Employee is unable to perform any of his usual duties to the
Company on a  full-time  basis.  As used in this  Agreement,  the term  "Partial
Disability" shall mean a disability,  other than a total  disability,  such that
for  physical or mental  reasons,  the  Employee is unable to perform all of his
usual duties to the Company on a full-time basis.
      7.    Termination.
            (a) Termination by Death. If the Employee dies during the Employment
Period,  the Company's  obligations under this Agreement shall terminate six (6)
months  after the date of death and the  Employee's  estate shall be entitled to
all arrearages of Base  Compensation and expenses.  In addition,  the Employee's
estate (or such other named  beneficiary)  shall be entitled to the amounts,  if
any,  as may be  payable  to his  estate  or  beneficiaries  under  policies  of
insurance maintained by the Company.
            (b)  Termination  for  Cause.  This  Agreement  and  the  Employee's
employment  with  the  Company  may be  terminated  for  Cause  at any  time  in
accordance with  subparagraph (d) of this Section 7. In the event this Agreement
is terminated  for Cause,  the Employee  shall be entitled to all  arrearages of
Base  Compensation and expenses through the Date of Termination but shall not be
entitled  to  further  compensation.  As  used in this  Agreement,  and  without
limitation, the term "Cause" shall mean:
            (i) an act or acts of dishonesty constituting criminal
acts by the Employee resulting or intended to result directly or

                                      9

<PAGE>



indirectly in gain to or personal enrichment of the Employee at the
Company's expense;
            (ii)  the commission of any crime involving fraud,
embezzlement or theft by the Employee against the Company;
            (iii) engaging in competition  with the Company,  including taking a
management  position with, or control of, a business engaged in the manufacture,
sale or distribution of a class of products or service which  constituted 15% or
more of the sales or gross  income of the Company and its  associated  companies
during the fiscal year of the Company  immediately  preceding the termination of
the Employee's employment.
            (c)  Termination  at the Option of the Employee.  This Agreement and
the Employee's employment with the Company may be terminated at any time, at the
election of the Employee, for Good Reason in accordance with subparagraph (d) of
this Section 7. In the event this Agreement is terminated  for Good Reason,  the
Employee shall be paid during the remainder of the Employment  Period  (computed
without  giving  effect  to  the  earlier  termination   hereunder),   his  Base
Compensation  (other than due to Partial Disability) at the rate in effect as of
the Date of Termination,  and shall continue to be entitled to employee benefits
as if he were still employed by the Company, until completion of such Employment
Period (computed without giving effect to the earlier termination hereunder). As
used in this  Agreement,  and without  limitation,  the term "Good Reason" shall
mean:

                                      10

<PAGE>



            (i) the assignment to the Employee of duties  inconsistent  with the
office of Vice President and Chief Financial  Officer of the Company or his then
current  office,  the removal of the  Employee  from such office or  substantial
reduction   in  the   nature   or  status  of  the   Employee's   then   current
responsibilities;
            (ii) the reduction of the Employee's then current Base
Compensation (other than due to Partial Disability) ;
            (iii) the relocation of the Company's principal executive offices to
a location  more than fifty (50)  miles  from the  Company's  current  principal
executive  offices or the  transfer  of the  Employee  to a place other than the
Company's   principal  executive  offices  (excepting  required  travel  on  the
Company's  business in a manner  substantially  similar to the  Employee's  then
current business travel obligations); and
            (iv) the failure by the Company to continue to provide the  Employee
with  benefits at least as  favorable  as those in which the  Employee  was then
participating.
            (d)  Notice  of  Termination.   Any  purported  termination  of  the
Employee's  employment  shall be communicated by a written notice of termination
to the other party  hereto and specify the Date of  Termination  (the "Notice of
Termination").  Such notice shall  indicate a specific  terminated  provision in
this Agreement which is relied upon, recite the facts and circumstances  claimed
to provide the basis for such  termination  and specify the Date of Termination.
As used in this Agreement,  the term "Date of  Termination"  shall mean the date
specified in the Notice of Termination, which date

                                      11

<PAGE>



shall not be less than  thirty  (30) nor more than sixty (60) days from the date
the Notice of Termination is given. If within thirty (30) days from the date the
Notice of Termination  is given,  the party  receiving such notice  notifies the
other  party that a dispute  exists  concerning  such  termination,  the Date of
Termination shall be the date on which the dispute is finally resolved. The Date
of  Termination  shall be extended by a notice of dispute only if such notice is
given in good faith and the party giving such notice  pursues the  resolution of
such dispute with reasonable diligence. Notwithstanding the pendency of any such
dispute,   the  Company  will  continue  to  pay  the  Employee  his  full  Base
Compensation  in effect as of the date of the Notice of Termination and continue
the Employee as a participant in all  compensation,  benefit and insurance plans
in which he was  participating  at such  date,  until  the  dispute  is  finally
resolved.  Amounts paid under this subparagraph (d) are in addition to all other
amounts due under this  Agreement and shall not be offset  against or reduce any
other amounts due under this Agreement.
      8. Change in Control. In the event of a Change in Control and, as a result
of such  Change in Control,  the  Employee is  terminated  without  Cause or the
Employee  elects to terminate his employment for any reason as a result thereof,
then the Employee shall receive the following benefits:
            (a) The Company shall pay to the Employee his full Base Compensation
at the rate in effect at the time of the Notice of Termination  through the Date
of Termination.

                                      12

<PAGE>



            (b) In lieu of any further  Base  Compensation  payments for periods
subsequent to the Date of Termination,  the Company shall pay to the Employee as
severance pay not later than the fifth day following the Date of Termination,  a
lump sum payment (the  "Severance  Payment")  equal to 2.99 times the average of
the annual  Compensation  which was  payable to the  Employee by the Company and
includible in the  Employee's  gross income for federal  income tax purposes for
the five (5) calendar  years, or for the portion of such period during which the
Employee was actually  employed by the Company if the Employee has been employed
by the Company for less than five (5) calendar  years  preceding  the earlier of
the calendar year in which a Change in Control  occurred or the calendar year of
the Date of Termination (the "Base Period"). Such average shall be determined in
accordance with the provisions of Section  280G(d) of the Internal  Revenue Code
of  1986  as  amended  (the  "Code").  As  used  in  this  Agreement,  the  term
"Compensation"  shall  mean and  include  every  type  and form of  compensation
includible in the  Employee's  gross income in respect of his  employment by the
Company including  compensation income recognized as a result of the exercise of
stock options or sale of the stock so acquired,  except to the extent  otherwise
provided in  Congressional  or Joint  Committee  Reports or  temporary  or final
regulations interpreting Section 280G(d) of the Code.
            (c) The  Severance  Payment  shall be  reduced  by the amount of any
other  payment or the value of any  benefit  received  or to be  received by the
Employee in connection with the termination of his

                                      13

<PAGE>



employment or contingent upon a Change in Control  (whether  payable pursuant to
the terms of this Agreement,  any other plan,  agreement or arrangement with the
Company)  unless (i) the Employee shall have  effectively  waived his receipt or
enjoyment  of such  payment  or  benefit  prior  to the date of  payment  of the
Severance  Payment,  (ii) in the opinion of tax counsel  selected by the Company
such other payment or benefit does not constitute a "parachute  payment"  within
the meaning of Section  280G(b)(2)  of the Code, or (iii) in the opinion of such
tax counsel,  the Severance Payment (in its full amount or as partially reduced,
as the case may be)  plus  all  other  payments  or  benefits  which  constitute
"parachute  payments"  within the meaning of Section  280G(b)(2) of the Code are
reasonable  compensation file services actually rendered,  within the meaning of
Section 280G(b)(4) of the Code, and such payments are deductible by the Company.
The  value  of any  non-cash  benefit  or any  deferred  cash  payment  shall be
determined  by  the  Company  in  accordance  with  the  principles  of  Section
280G(d)(3) and (4) of the Code.
            (d)  Except to the  extent  that  Congressional  or Joint  Committee
Reports or temporary or final regulations  interpreting Section 280G of the Code
specify that such  payments  would  result,  under  subsection  (c) above,  in a
reduction in the Severance Payment:
            (i) The Company shall pay to the Employee,  not later than the fifth
day following the Date of Termination, a lump sum amount equal to the sum of (x)
any bonus  compensation  which has been  allocated  or awarded for a fiscal year
preceding the Date of

                                      14

<PAGE>



Termination  but has not yet been paid,  and (y) a pro rata portion of any bonus
compensation which the Employee has earned for the fiscal year in which the Date
of  Termination  occurs  determined by multiplying  the Employee's  prior years'
bonus  compensation by a fraction equal to the number of full calendar months in
the fiscal year prior to the Date of Termination over twelve.
            (ii) The Company shall also pay all legal fees and expenses incurred
by the  Employee as a result of such  termination  (including  all such fees and
expenses, if any, incurred in contesting or disputing any such termination or in
seeking to obtain or enforce any right or benefit provided by this Agreement).
            (e) If it is  established  pursuant  to a final  determination  of a
court or an Internal Revenue Service proceeding that,  notwithstanding  the good
faith of the  Employee  and the Company in applying the terms of this Section 8,
the aggregate  "parachute  payments"  paid are in an amount that would result in
any portion of such "parachute  payments" not being deductible by the Company by
reason of Section 280G of the Code,  then the Employee  shall have an obligation
to pay the Company  upon demand an amount equal to the sum of (i) the portion of
the aggregate  "parachute  payments" paid that would not be deductible by reason
of Section 280G of the Code and (ii)  interest on the amount set forth in clause
(i) of this  sentence  at the  applicable  Federal  rate (as  defined in Section
1274(d) of the Code) from the date of receipt of such  excess  until the date of
such payment.

                                      15

<PAGE>



            (f) As used in the  Agreement,  the term  "Change in Control"  shall
mean a change in control of a nature  that would be  required  to be reported in
response  to Item  6(e) of  Schedule  14A of  Regulation  14A  issued  under the
Securities Exchange Act of 1934, as amended (the "Exchange Act") as in effect as
of the date  hereof  (regardless  of whether or not a Proxy  Statement  is being
filed pursuant to such Regulation at such time), or if Item 6(e) is no longer in
effect,  any subsequent  regulation  issued under the Exchange Act for a similar
purpose,  whether or not the Company is subject to such reporting  requirements;
provided,  that without limitation,  such a change in control shall be deemed to
have occurred if:
            (i)  any  "person"  other  than  the  Employee  is  or  becomes  the
"beneficial  owner" (as defined in Rule 13d-3 under the Exchange Act),  directly
or  indirectly,  of  securities of the Company  representing  25% or more of the
combined voting power of the Company's then outstanding securities;
            (ii) during any period of two  consecutive  years (not including any
period prior to the date of the Agreement),  individuals who at the beginning of
such period  constitute  the Board of  Directors,  and any new  director,  whose
election by the Board or nomination  for election by the Company's  stockholders
was approved by a vote of at least  two-thirds  of the  directors  then still in
office  who  either  were  directors  at the  beginning  of the  period or whose
election or nomination for elections was previously

                                      16

<PAGE>



approved, cease for any reason to constitute a majority of the
Board; or
            (iii) the  business  of the  Company is  disposed  of by the Company
pursuant to a liquidation, sale of assets of the Company, or otherwise.
      9. Confidential  Information.  The Employee  acknowledges an obligation of
confidentiality  to the Company and shall not divulge,  disclose or  communicate
any trade  secret,  private or  confidential  information  or other  proprietary
knowledge of the Company or its associated companies obtained or acquired by him
while so employed.  This  restriction  shall apply after the  termination of the
Employee's employment without limit in point of time but shall cease to apply to
information  or  knowledge  which  may come  into  the  public  domain  or whose
disclosure  may be  required  by law or court  order or  pursuant to the written
consent of the Corporation.
      10. Return of Information.  Upon  termination of employment,  the Employee
agrees to not take with him and to deliver to the  Company all  records,  notes,
data, memoranda,  models,  equipment,  blueprints,  drawings,  manuals, letters,
reports and all other materials of a secret or  confidential  nature relating to
the business of the Company which are in possession or control of the Employee.
      11.   General Provisions.
            (a)   This Agreement contains the entire transaction
between the parties, and there are no other representations,

                                      17

<PAGE>



warranties, conditions or agreements relating to the subject matter
of this Agreement.
            (b)  The  waiver  by any  party  of any  breach  or  default  of any
provision of this Agreement shall not operate or be construed as a waiver of any
subsequent breach.
            (c)  This  Agreement  may  not be  changed  orally  but  only  by an
Agreement  in  writing  duly  executed  on  behalf of the  party  against  which
enforcement of any waiver, change, modification, consent or discharge is sought.
            (d) This Agreement shall be binding upon and be enforceable  against
the  Company  and  its  successors  and  assigns.  Insofar  as the  Employee  is
concerned, this Agreement is personal and cannot be assigned.
            (e) This Agreement may be executed in one or more counterparts, each
of which shall be deemed an original, but all of which together shall constitute
one and the same instrument.
            (f) This Agreement shall be construed  pursuant to and in accordance
with the laws of the State of New Jersey.
            (g) If any term or provision of this  Agreement is held or deemed to
be  invalid  or  unenforceable,  in whole or in  part,  by a court of  competent
jurisdiction,  this  Agreement  shall  be  ineffective  to the  extent  of  such
invalidity or  unenforceability  without  rendering invalid or unenforceable the
remaining terms and provisions of this Agreement.
            (h)   Any dispute, grievance or controversy arising under
or in connection with this Agreement shall be referred to the Board

                                      18

<PAGE>



of Directors of the Company and shall be dealt with by personal discussion,  and
if not  satisfactorily  resolved,  shall be submitted to  arbitration  under the
Rules of the American Arbitration Association in New York City.
            (i) Any consent of the Company  required under this Agreement  shall
not be unreasonably withheld or delayed.
      IN WITNESS  WHEREOF,  the parties have executed this Agreement on the date
first above written.
                                    COMPANY:

                                    Bio-Reference Laboratories, Inc.



                                    By /s/Marc D. Grodman
                                      President
                                      Duly Authorized


                                    EMPLOYEE:



                                    /s/Sam Singer
                                    Sam Singer





                                      19





                                 Exhibit 10.8

                         ASSET SALE/PURCHASE AGREEMENT


      AGREEMENT made as of the 2nd day of December 1999 by and among The Medical
Marketing Group, Inc., a New York corporation with a principal place of business
at 401 Columbus  Avenue,  Valhalla,  New York 10595  ("MMGI") and Craig  Allison
residing at 1 Newton Court, Croton-on-Hudson,  New York 10520 ("Allison") on the
one hand and Bio-Reference Laboratories, Inc., a New Jersey corporation with its
principal  place of  business  at 481 Edward H. Ross Drive,  Elmwood  Park,  New
Jersey 07407 ("BRLI") on the other hand.

                             W I T N E S S E T H :
                             -------------------


      WHEREAS,  Allison is the  president,  chief  executive  officer and having
acquired Dean Steinman's ("Steinman")  approximately 48% capital stock interest,
is now the owner of approximately 93% of the outstanding  capital stock of MMGI,
and


      WHEREAS,  MMGI,  among other  activities,  is engaged in selling  Internet
website design and other Internet-oriented services to medical professionals and
other  healthcare   professionals   including  individual  and  group  physician
practices,  hospitals,  medical groups,  medical  societies,  health centers and
healthcare  facilities  (referred  to at  times as the  "WEB  Business")  and in
connection  therewith,  is the owner of the  domain  names  listed in  Exhibit A
hereto (the "Domain Names"), and


      WHEREAS,  MMGI has created certain  algorithms for placement on commercial
search engines associated with the Domain Names, and


      WHEREAS,  MMGI has entered  into formal and informal  agreements  with the
healthcare  clients set forth on Exhibit B attached hereto to provide website as
well as non-website services, and


      WHEREAS,  MMGI and  Allison  desire  that  MMGI sell and BRLI  desires  to
purchase certain assets utilized by MMGI in the operation of the WEB Business as
well as MMGI's rights under its agreements and arrangements  with the healthcare
clients set forth in Exhibit B to the extent they relate to website services, on
the terms and conditions herein set forth.


      NOW,  THEREFORE,  in  consideration of the mutual covenants and agreements
herein contained and other good and valuable consideration,  the receipt whereof
and  sufficiency  of which  are  hereby  acknowledged,  it is  hereby  agreed as
follows:


<PAGE>





1.    Sale and Transfer of the WEB Business

      Based upon the representations and warranties herein contained
and subject to the terms and conditions hereinafter set forth;

      (A) MMGI  shall  sell,  transfer,  assign  and  deliver to BRLI all of its
right,  title and interest in the WEB Business including all of its right, title
and interest to any and all assets utilized or capable of being utilized by MMGI
in the WEB  Business  including  but not limited to the Domain  Names,  software
applications,  search engines, database engines, data, HTML pages, search engine
designs and algorithms  for inclusion in other  Internet-based  search  engines,
software and database  licenses,  custom software and custom  applications  with
associated source and data, licenses, lists, links and authorizations for links,
banners  and  agreements  for  banners  and  associated   advertising  revenues,
advertising,  advertising  contracts and agreements,  and listing contracts with
associated  revenues  as well as any and all custom  programs,  applications  or
solutions  that MMGI has  developed  itself or hired others to produce for it if
any of those programs,  applications or solutions are useful and/or  appropriate
to the operation of the WEB Business (such assets being collectively referred to
as the "WEB  Assets")  and all of its right,  title and interest to all website-
based agreements, partial agreements or arrangements with the healthcare clients
set  forth on  Exhibit B hereto as well as its  rights  to all  future  revenues
therefrom (collectively the "WEB Business Agreements").

      (B) BRLI shall  issue and deliver  140,000  shares of its  authorized  but
unissued  common stock in payment for the WEB Business  including the WEB Assets
and the WEB Business  Agreements,  as hereinafter  described (with an additional
60,000 of such  shares to be  issued  and  delivered  in  consideration  for the
Non-Competition Agreements hereinafter described).

2.    Closing

      (A) The closing of such sale and purchase (the "Closing") shall take place
at the offices of BRLI at 481 Edward H. Ross  Drive,  Elmwood  Park,  New Jersey
07407 at 9:00 o'clock A.M. (EST) on Thursday, December 2, 1999 or at such place,
date and time  thereafter  as the parties  hereto  shall  mutually  agree,  in a
writing  executed by BRLI on the one hand and by MMGI on the other.  The date of
the closing is hereinafter referred to as the "Closing Date."

      (B) At the Closing, MMGI shall execute and deliver a bill of sale to BRLI,
in the form of  Exhibit C hereto  (the  "Bill of Sale")  and such other good and
sufficient duly executed  instruments of transfer and conveyance,  including any
and all required

                                      2

<PAGE>



authorizations,  assignments  and consents,  satisfactory in form and content to
BRLI, as shall vest in BRLI,  all of MMGI's right,  title and interest in and to
the WEB Assets and the WEB Business Agreements,  free and clear of all liens and
encumbrances,  and as shall enable BRLI to operate the WEB Business as currently
operated by MMGI, without impediment.

      (C) At the Closing, BRLI on the one hand and MMGI, Allison and Steinman on
the  other  will  each  execute  and  deliver  to  each  other,  Non-Competition
Agreements  substantially  in the form of  Exhibits  D-1,  D-2 and D-3  attached
hereto.

      (D) At the Closing, BRLI on the one hand and MMGI and Allison on the other
will  execute  and  deliver to each other an  Advertising  Consulting  Agreement
substantially in the form of Exhibit E attached hereto.

      (E) (1) At the Closing,  BRLI shall issue and deliver an aggregate 140,000
shares of its authorized  but unissued  common stock in full payment for the WEB
Business (including the WEB Assets and the WEB Business Agreements),  registered
in the names of the  persons  and  entities  designated  by MMGI as set forth in
Exhibit F hereto,  in the amounts set forth  opposite  their  respective  names,
against  receipt of  appropriate  investment  letters  prepared by BRLI and duly
executed by each such proposed stockholder.

            (2) At the  Closing,  BRLI shall  execute and  deliver an  aggregate
60,000 shares of its  authorized  but unissued  common stock to MMGI and Allison
and a cash  payment  of  $10,000  to  Steinman  in  consideration  for the three
Non-Competition Agreements, in the amounts therein set forth.

            (3) All of the said  200,000  shares  of  common  stock  will not be
registered under the Securities Act of 1933; each of the stock certificates will
contain a  restrictive  legend and  transfer  stops will be placed  against  the
shares of stock.

      (F) At the  Closing,  BRLI shall  deliver  its check in the sum of $15,000
payable  to MMGI,  to  MMGI,  in  accordance  with  the  Advertising  Consulting
Agreement, representing the initial retainer thereunder.

      (G) At the Closing,  BRLI shall execute and deliver an Option Agreement to
MMGI,   substantially  in  the  form  of  Exhibit  G  hereto,  granting  options
exercisable to purchase a maximum  100,000 shares of BRLI  authorized but issued
common stock on the terms and conditions therein set forth.


3.    Representations and Warranties Concerning MMGI and the WEB
      ----------------------------------------------------------
      Business

                                      3

<PAGE>




      (A) As an  inducement  to BRLI to  enter  into  this  Asset  Sale/Purchase
Agreement  (the  "Agreement")  and the  MMGI  Non-  Competition  Agreement,  the
Advertising  Consulting  Agreement and the Option  Agreement  (collectively  the
"Subsidiary  Agreements") as well as the Non-Competition  Agreement with Allison
and to effectuate the transactions  contemplated hereby and thereby,  MMGI on an
absolute basis and Allison to his actual knowledge and belief,  hereby severally
represent and warrant to BRLI that:

            (1) MMGI is a corporation  duly organized,  validly  existing and in
good  standing  under  the laws of the  State of New York and has all  requisite
corporate  power and authority to enter into this  Agreement and the  Subsidiary
Agreements,  to consummate the transactions herein and therein contemplated,  to
own, lease and operate its properties and to carry on its business including the
WEB Business as it is now being conducted.

            (2) The execution and delivery of this  Agreement and the Subsidiary
Agreements, the consummation of the transactions herein and therein contemplated
and the performance,  observance and fulfillment by MMGI of all of the terms and
conditions  hereof  and  thereof  on its  part to be  performed,  observed,  and
fulfilled, (a) have all been approved and effectively authorized by MMGI's board
of directors and by the vote of its stockholders and no other proceedings on the
part of MMGI or its  stockholders  are necessary to authorize this Agreement and
the Subsidiary Agreements,  or the consummation of the transactions contemplated
hereby and  thereby,  (b) do not and will not  (either  immediately  or with the
lapse of time, or with notice,  or both) (i) conflict with any of the provisions
of the  Certificate  of  Incorporation  or by-laws  of MMGI,  (ii)  violate  any
provisions of any judicial or administrative  order,  award,  judgment,  decree,
statute, rule or regulation  applicable to MMGI or any of its properties,  (iii)
conflict with or result in a breach of, constitute a default under,  contravene,
result in a  forfeiture  of a right  under,  or result  in the  acceleration  of
payment or performance under, any note, bond, mortgage,  indenture, deed, trust,
license,  lease, agreement, or other instrument or obligation to which MMGI is a
party  or by  which  MMGI or any of the WEB  Assets  or any of the WEB  Business
Agreements  may be  bound  or  affected,  or  (iv)  result  in the  creation  or
imposition of any lien,  security interest,  charge or other encumbrance against
any of the WEB Assets or any of the WEB Business Agreements.

            (3) This Agreement and each of the Subsidiary  Agreements,  has been
duly and validly  executed and delivered by MMGI and constitute  valid,  binding
and  enforceable   obligations  of  MMGI.  Although  an  involuntary  bankruptcy
proceeding  was  initiated  by  creditors  against  MMGI on July 22, 1999 in the
United States Bankruptcy Court for the Southern District of New York (Docket No.

                                      4

<PAGE>



99B-21772),  such  proceeding  was dismissed with prejudice on or about November
19,  1999.  With the  exception  of such  dismissed  proceeding,  no petition in
bankruptcy  has been filed by or  against  MMGI.  Furthermore,  no  petition  in
bankruptcy  has been filed by or  against  Allison.  MMGI has the right,  power,
legal  capacity and  authority to enter into and perform its  obligations  under
this Agreement and each of the Subsidiary Agreements and no consent of any third
party is necessary with respect thereto which has not been obtained.

            (4) Except as  described  in Exhibit H hereto,  there is no material
action,  dispute,  claim,  litigation,  arbitration,   investigation,  or  other
proceeding,  at law or in equity or by or before  any court or  governmental  or
administrative  body (U.S. or foreign),  pending or threatened against MMGI, its
business or properties, or with respect to the transactions contemplated by this
Agreement and each of the Subsidiary Agreements,  and MMGI is not subject to any
adverse  judicial,  governmental or agency  judgment,  decree or order, nor does
MMGI or  Allison  know  of any  basis  for  any  such  action,  dispute,  claim,
litigation, arbitration, investigation or other proceeding.

            (5) MMGI has made adequate  provision  for, and is not in default of
any current or long-term liabilities (including contingent  liabilities),  debts
or obligations, contractual or otherwise.

            (6) MMGI has paid,  or made  adequate  provision for the payment of,
any  and  all  outstanding  tax  (income,   employment,  sales  and  all  other)
liabilities  and MMGI has  properly  prepared  and duly  filed  all tax  returns
required to be filed by it through the date hereof.

            (7) MMGI has no  subsidiary  nor does it own or control any stock of
or have any proprietary interest in any other entity.

            (8)  The  assets  being  sold to BRLI  hereunder  do not  constitute
substantially all of MMGI's assets.

            (9) Upon completion of the Closing as described in Section 2 herein,
BRLI will be vested in and will own all of MMGI's  right,  title and interest in
and to the WEB  Assets  and the WEB  Business  Agreements  free of all liens and
encumbrances and there shall be no impediment to BRLI operating the WEB Business
as currently operated by MMGI.

      (B) The  foregoing  representations  and  warranties  are  made  with  the
knowledge and expectation that BRLI is placing complete reliance thereon.



                                      5

<PAGE>



4.    Representations and Warranties of BRLI

      (A) As an  inducement  to  MMGI  to  enter  into  this  Agreement  and the
Subsidiary  Agreements and consummate the transactions  contemplated  hereby and
thereby, BRLI represents and warrants:

            (1) BRLI is a corporation  duly organized,  validly  existing and in
good  standing  under the laws of the State of New Jersey and has all  requisite
corporate  power and authority to enter into this  Agreement and the  Subsidiary
Agreements,  to consummate the transactions herein and therein contemplated,  to
own,  lease and operate its properties and to carry on its business as it is now
being conducted,  and is duly licensed,  authorized and qualified to do business
and is in good  standing  in all  jurisdictions  in  which  the  conduct  of its
business  or the  ownership  or leasing of its  properties  requires it to be so
qualified, authorized or licensed.

            (2) The execution and delivery of this  Agreement and the Subsidiary
Agreements, the consummation of the transactions herein and therein contemplated
and the performance,  observance and fulfillment by BRLI of all of the terms and
conditions  hereof  and  thereof,  on its part to be  performed,  observed,  and
fulfilled, (a) have all been approved and effectively authorized by BRLI's board
of  directors  and no other  proceedings  on the part of BRLI are  necessary  to
authorize execution and delivery of this Agreement and the Subsidiary Agreements
or the consummation of the transactions  contemplated hereby and thereby, (b) do
not and will not (either  immediately or with the lapse of time, or with notice,
or  both)  (i)  conflict  with  any  of  the   provisions  of  the  Articles  of
Incorporation  or by-laws of BRLI,  violate any  provisions  of any  judicial or
administrative  order,  award,  judgment,  decree,  statute,  rule or regulation
applicable to BRLI or any of its properties,  (iii) conflict with or result in a
breach of, constitute a default under,  contravene,  result in a forfeiture of a
right under, or result in the acceleration of payment or performance  under, any
note, bond, mortgage,  indenture,  deed, trust, license,  lease,  agreement,  or
other  instrument or obligation to which BRLI is a party or by which BRLI or any
of its  properties  may be bound or affected,  or (iv) result in the creation or
imposition of any lien,  security interest,  charge or other encumbrance against
any properties of BRLI.

            (3) This Agreement and the Subsidiary  Agreements have been duly and
validly  executed  and  delivered  by BRLI and  constitute  valid,  binding  and
enforceable  obligations of BRLI. BRLI has the right,  power, legal capacity and
authority to enter into and perform its obligations under this Agreement and the
Subsidiary  Agreements  and no  consent  of any third  party is  necessary  with
respect thereto.


                                      6

<PAGE>



            (4)  There  is  no  material  action,  dispute,  claim,  litigation,
arbitration,  investigation,  or other proceeding,  at law or in equity or by or
before any court or  governmental  or  administrative  body (U.S.  or  foreign),
pending or threatened against BRLI, its business or properties,  or with respect
to the  transactions  contemplated  by  this  Agreement  and/or  the  Subsidiary
Agreements,  and BRLI is not subject to any adverse  judicial,  governmental  or
agency  judgment,  decree or order, nor does BRLI know of any basis for any such
action,  dispute,  claim,  litigation,   arbitration,   investigation  or  other
proceeding.

            (5) All of the shares of BRLI common stock issuable pursuant to this
Agreement and the  Subsidiary  Agreements  are duly  authorized  and will,  when
issued, be validly issued, fully paid (assuming delivery of the Bill of Sale and
MMGI and Allison's Non- Competition Agreements and payment in full of the Option
Exercise  Price)  and  non-assessable,  and none of such  shares  will have been
issued in violation of the pre-emptive rights of any BRLI shareholder.

      (B) The  foregoing  representations  and  warranties  are  made  with  the
knowledge and expectation  that MMGI and Allison are placing  complete  reliance
thereon.


5.    Indemnification

      (A) Provided that the  representations  made by BRLI in this Agreement and
the  Subsidiary  Agreements  are  accurate  and BRLI is in  compliance  with its
obligations under this Agreement,  MMGI and Allison and each of them,  severally
hereby agree to indemnify and hold harmless BRLI against and in respect of:

            (1) all liabilities and obligations of, or claims against BRLI based
on liabilities and obligations of MMGI unless same shall result from the acts or
omissions of BRLI;

            (2) any damage  resulting  from any material  misrepresentation,  or
nonfulfillment of any agreement on the part of MMGI or Allison or either of them
under  this  Agreement  and/or  any of the  Subsidiary  Agreements  or from  any
material  misrepresentation  in  or  omission  from  any  certificate  or  other
instrument  furnished or to be furnished  to BRLI under this  Agreement  and the
Subsidiary  Agreements;  (provided that with respect to indemnification based on
material   misrepresentations,   Allison's   indemnification   is   limited   to
indemnification for damages resulting from a violation of those  representations
and warranties which are deemed made upon his actual knowledge and belief); and


                                      7

<PAGE>



            (3)  all  actions,   suits,   proceedings,   demands,   assessments,
judgments, costs and expenses incident to any of the foregoing.

      (B)  Provided  that the  representations  made by MMGI and Allison in this
Agreement and the Subsidiary Agreements are accurate and MMGI and Allison are in
compliance with its and his obligations  under this Agreement and the Subsidiary
Agreements,  BRLI hereby  agrees to indemnify and hold harmless MMGI and Allison
and each of them against and in respect of:

            (1) all  liabilities  and obligations of, or claims against MMGI and
Allison or any of them with respect to the  operation of the WEB  Business,  for
periods  after the Closing as a result of BRLI's  purchase  of the WEB  Business
hereunder or BRLI's operation of the WEB Business  thereafter  unless same shall
result from the  intentional or grossly  negligent acts or omissions of MMGI and
Allison or either of them;

            (2)  any  damage  or   deficiency   resulting   from  any   material
misrepresentation, breach of warranty, or nonfulfillment of any agreement on the
part of BRLI under this  Agreement  and the  Subsidiary  Agreements  or from any
material  misrepresentation  in  or  omission  from  any  certificate  or  other
instrument  furnished or to be furnished  by BRLI under this  Agreement  and the
Subsidiary Agreements; and

            (3)  all  actions,   suits,   proceedings,   demands,   assessments,
judgments, costs and expenses incident to any of the foregoing.


6.    Conditions to BRLI's Obligation to Close

      The obligation of BRLI to consummate  this  Agreement  shall be subject to
each of the following conditions:

      (A) Each of the  representations  and warranties  made by MMGI and Allison
and each of them herein shall be true and accurate as of the date hereof  except
as affected by the transactions expressly contemplated by this Agreement.

      (B) Each and every  covenant,  agreement  and  condition  required by this
Agreement to be performed or complied with by MMGI or its  affiliates  and/or by
Allison at or prior to the Closing shall have been performed or complied with at
or prior to the Closing hereunder.

      (C) MMGI and Allison and each of them shall have  delivered to BRLI all of
the executed agreements, instruments,  certificates and other documents referred
to hereinabove required to be delivered by

                                      8

<PAGE>



it  and/or  him  at or  prior  to  the  Closing  including  the  Bill  of  Sale,
Non-Competition Agreements and Advertising Consulting Agreement.

      (D) Each of the  individuals  and  entities  set forth in Exhibit F hereto
shall have delivered to BRLI executed investment letters satisfactory in form to
BRLI's securities counsel.

      (E) MMGI shall have delivered its written  agreement to BRLI that it will,
within five (5) business  days after the Closing,  in a letter  approved by BRLI
(which   approval  shall  not  be   unreasonably   withheld),   provide  written
notification to each of the healthcare clients listed in Exhibit B hereto of its
transfer to BRLI of the WEB  Business  and that it will use its best  efforts to
obtain each such client's  consent to the transfer and  continuation as a client
of BRLI. In addition,  MMGI shall promptly deliver to BRLI all executed consents
which it is able to obtain using its best efforts,  to the assignment to BRLI of
each of the WEB Business Agreements as well as executed  authorizations which it
has been  able to  obtain  using  its best  efforts,  from  each of the  service
providers to the WEB Business  permitting  BRLI to utilize the same services and
service  providers  in BRLI's  operation  of the WEB  Business as are  currently
utilized by MMGI, and at the same rates.

      (F) No suit or action,  no investigation or inquiry by any  administrative
agency or governmental  body, and no legal or  administrative  proceeding  shall
have been  instituted or  threatened  which in any way questions the validity or
legality of this Agreement or the transactions contemplated thereby, at or prior
to the Closing.

      (G) Each and every one of the transactions required herein to occur at the
Closing shall have been completed.


7.    Conditions to MMGI's Obligation to Close

      The obligation of MMGI to consummate  this  Agreement  shall be subject to
each of the following conditions:

      (A) Each of the  representations  and warranties made by BRLI herein shall
be  true  and  accurate  as of  the  date  hereof  except  as  affected  by  the
transactions expressly contemplated by this Agreement.

      (B) Each and every  covenant,  agreement  and  condition  required by this
Agreement to be  performed  or complied  with by BRLI at or prior to the Closing
shall have been performed or complied with at or prior to the Closing hereunder.


                                      9

<PAGE>



      (C) BRLI shall have delivered to MMGI and Allison and each of them, all of
the executed agreements, instruments,  certificates and other documents referred
to  hereinabove  required  to be  delivered  by it at or  prior  to the  Closing
including the Non-Competition  Agreements,  the Advertising Consulting Agreement
and the Option Agreement.

      (D) Each of the  individuals  and  entities  set forth in Exhibit F hereto
shall have received that number of shares of BRLI common stock registered in his
or its name as are set  forth  opposite  their  respective  names in  Exhibit  F
(aggregating 140,000 shares).

      (E) MMGI and Allison  shall have  received an aggregate  60,000  shares of
BRLI  common  stock  registered  in  their  respective  names  pursuant  to  the
Non-Competition Agreements.

      (F) No suit or action,  no investigation or inquiry by any  administrative
agency or governmental  body, and no legal or  administrative  proceeding  shall
have been  instituted or  threatened  which in any way questions the validity or
legality of this Agreement or the transactions contemplated thereby, at or prior
to the Closing.

      (G) Each and every one of the transactions required herein to occur at the
Closing shall have been completed.


8.    Further Covenants and Agreements of MMGI and BRLI
      -------------------------------------------------

      (A) Within  seven (7) business  days after the Closing,  MMGI will provide
BRLI with all written information  necessary to enable BRLI to acquire,  license
or  take  over  MMGI's  interest  in all  custom  software  utilized  by MMGI in
operating the WEB Business.  MMGI  represents  and warrants to BRLI that it will
use its best efforts to obtain  transfers by consent or through licenses to BRLI
of all of such software products which are not standard, commercially available,
over-the-counter  software products. MMGI agrees to fully cooperate with BRLI on
a timely basis in order to enable BRLI to acquire such software products.

      (B) BRLI  agrees  that after the  Closing,  MMGI may  continue  to provide
website-design  services and other Internet services for non-healthcare clients,
as well as  non-Internet  website  services for  healthcare  and  non-healthcare
clients, free and clear of any right, title or interest therein by BRLI.

      (C) MMGI covenants and agrees that immediately  after the Closing,  except
as provided in paragraph  (D) of this Section 8, MMGI shall  terminate and cease
the conduct of any and all Internet website business of any kind for any and all
healthcare or healthcare-related Internet website design, development,

                                      10

<PAGE>



implementation,  programming  maintenance,  linking,  search engine development,
revenue or non-revenue  producing  activities for individual or group  physician
practices, hospitals, clinics, laboratories,  medical groups, medical societies,
health centers and healthcare  facilities of any kind  whatsoever  (collectively
"Healthcare and Healthcare-Related Businesses"), during the one (1) year term of
the  Advertising  Consulting  Agreement plus any renewals (up to three (3) years
thereof),  and for an additional  one (1) year period after  termination  of the
Advertising Consulting Agreement (i.e., a maximum five (5) year period).

      (D)   Anything to the contrary herein contained
notwithstanding, MMGI shall have the right;

            (1) to submit  sites hosted by BRLI to Internet  Search  Engines for
purposes of increasing traffic to the site or sites hosted by BRLI. In the event
that BRLI shall wish to utilize the website design services of MMGI at any time,
MMGI agrees to provide such services to BRLI upon BRLI's written  request at the
rates as set forth in Exhibit "I," attached hereto and made a part hereof.  This
provision is a  substantial  part of the  consideration  for this  Agreement and
shall  remain in effect  for five (5) years from the  Closing.  BRLI shall pay a
commission  to MMGI  for  web-design  services  sold on  behalf  of BRLI by MMGI
pursuant to BRLI's  written  request during such five (5) year period in the sum
of 40% of net revenues received by BRLI from the customer for such services when
received by BRLI;

            (2) to provide  Internet  website design  services to Healthcare and
Healthcare-Related  Businesses  whose  facilities are located in Westchester and
New  York  counties  in the  State of New York  during  the one (1) year  period
commencing at the Closing, provided that such services are limited solely to the
actual design, content,  programming and off-net site development of the website
and not to the  hosting  and  worldwide  hosting  aspects of the site;  that the
healthcare or healthcare-related site excepted is hosted on a BRLI website; that
regardless of any fee arrangements  that may otherwise be entered into, the said
healthcare  or  healthcare-related  client must be charged a website  design fee
payable to BRLI  pursuant to the fee  schedule  attached  hereto and made a part
hereof  as  Exhibit  "J";  and that  the fee to BRLI  must be paid to BRLI as an
initial fee before any other  Internet  website-  related fees are paid to MMGI.
The said  healthcare  client  shall be required to pay monthly or annual fees to
BRLI for website  hosting on standard terms and conditions for all BRLI Internet
Websites.  All website  maintenance fees shall be paid by the client to BRLI for
maintenance  to the  on-line  website  in  accordance  with  standard  terms and
conditions of all BRLI Internet Websites.

      (E) MMGI agrees and  covenants  with BRLI to provide a maximum 50 hours of
technical training related to the WEB Business during

                                      11

<PAGE>



the 90-day period commencing at the Closing,  and to provide a maximum 100 hours
of sales training  and/or support related to the WEB Business during the 180-day
period commencing at the Closing.  Such training shall be without charge to BRLI
and shall be provided to BRLI's designated  employees and agents. Any additional
training shall be at such additional  times and on such terms as the parties may
mutually agree upon as necessary and reasonable.

      (F)  MMGI  agrees  during  the  period  that  the  Advertising  Consulting
Agreement  is in full  force  and  effect  (the  "Measuring  Period")  to market
Internet-oriented  services to Healthcare and Healthcare-Related  Businesses for
linkage to and participation in the WEB Business conducted by BRLI. Any customer
unaffiliated  with the  healthcare  clients  set forth in  Exhibit B hereto  who
executes a contract  for such  services  during  the  Measuring  Period on terms
acceptable  to BRLI in its sole and  absolute  discretion  shall  be  deemed  an
"Additional  Customer."  Upon  delivery by MMGI through its sales efforts of the
1,000th  Additional  Customer  during  the  Measuring  Period,  BRLI  agrees and
covenants  to pay a  commission  to MMGI equal to fifteen  percent  (15%) of the
recurring  Internet access and website fees paid to BRLI pursuant to the initial
contract with such  Additional  Customer  (provided that said contract shall not
exceed three (3) years in duration  and is on terms  acceptable  to BRLI).  Such
commission  shall be  payable to MMGI  solely  with  respect  to any  Additional
Customers  after  the  1,000th  Additional  Customer,  solely  with  respect  to
contracts  executed  during the  Measuring  Period and only with respect to each
payment after it has actually been received by BRLI.


9.    Expenses

      Each  of the  parties  shall  pay  its  own  expenses  (including  without
limitation,  the fees and expenses of the agents,  representatives,  counsel and
accountants)  incidental to the preparation  and  consummation of this Agreement
and the Subsidiary Agreements.


10.   Brokerage

      Each party shall  indemnify  and hold the other free and harmless from all
losses,  damages,  costs, and expenses  (including  attorney's fees) that may be
suffered  as a  result  of  claims  brought  by any  broker  or  finder  seeking
compensation on account of this  transaction  arising out of the actions of such
party.


11.   Survival of Representations, Warranties, Agreements and
Covenants


                                      12

<PAGE>



      The parties agree that the representations,  warranties,  agreements,  and
covenants contained in this Agreement, the Subsidiary Agreements or in any other
documents  delivered in accordance  with or by virtue of this  Agreement and the
Subsidiary Agreements shall survive the execution and delivery of this Agreement
and the Subsidiary  Agreements and all other instruments in connection  herewith
or therewith.


12.   Notices

      All notices and other documents required or permitted to be given pursuant
to this Agreement  shall be in writing and shall be deemed to have been given if
delivered  by hand with an  acknowledgement  of  receipt  therefor  or mailed or
forwarded by registered or certified  mail or by Federal  Express to the parties
at the addresses  provided  above (or such other address for a party as shall be
specified by notice given pursuant to this paragraph).


13.   Binding Effect and Assignability

      This  Agreement and the  Subsidiary  Agreements  shall be binding upon and
shall  inure  to the  benefit  of the  parties  hereto  and  thereto  and  their
respective  successors and assigns. BRLI shall be permitted to assign its rights
(but not its obligations) hereunder to a wholly-owned subsidiary.


14.   Governing Law and Jurisdiction

      This  Agreement  and the  Subsidiary  Agreements  shall be  construed  and
enforced in accordance  with the laws of the State of New Jersey  without regard
to the principle of the conflict of laws.  The parties  hereto consent to the in
personam jurisdiction of the courts of the State of New Jersey and further agree
that any action with respect to this  Agreement  and the  Subsidiary  Agreements
shall be commenced and prosecuted only in such courts.  The parties hereby waive
trial by jury in any action or proceeding  arising under this  Agreement and the
Subsidiary Agreements.


15.   Remedies

      No remedy herein  conferred  upon or reserved to a party is intended to be
exclusive of any other available remedy, but each and every such remedy shall be
cumulative  and in addition to every other remedy given under this Agreement and
the  Subsidiary  Agreements  or  in  connection  with  this  Agreement  and  the
Subsidiary Agreements and now or hereafter existing at law or in equity.


                                      13

<PAGE>



16.   Entire Agreement

      This Agreement and the Subsidiary Agreements referred to herein constitute
the entire  agreement  among the  parties  with  respect to the  subject  matter
contained   herein  and  therein  and   supersede  all  prior   agreements   and
understandings,  oral or written.  This Agreement and the Subsidiary  Agreements
may not be amended or modified except in writing executed by each of the parties
hereto.


      IN WITNESS  WHEREOF,  the parties have executed this  Agreement on the day
and year first above written.

                              THE MEDICAL MARKETING GROUP, INC.



                              By /s/Craig Allison

                              Title Craig Allison, President



                              /s/Craig Allison
                              ----------------
                              Craig Allison (Individually)


                              BIO-REFERENCE LABORATORIES, INC.



                              By /s/Marc D. Grodman


                              Title Marc D. Grodman, President


                                      14




                                 Exhibit 10.9

                         ASSET SALE/PURCHASE AGREEMENT


      AGREEMENT  made as of the 14th day of December  1999 by and between  Right
Body Foods Inc., a New York  corporation with its principal place of business at
118 Jackson  Avenue,  Syosset,  Long Island,  New York 11791 ("RBF") and Rebecca
Klafter residing at 102 Bristol Drive, Woodbury, New York 11797 ("Klafter"), the
chief  executive  officer and sole  stockholder of RBF (Klafter and RBF being at
times  collectively  referred  to  as  the  "Sellers")  on  the  one  hand,  and
Bio-Reference  Laboratories,  Inc.,  a New Jersey  corporation  ("BRLI") and its
wholly-owned subsidiary,  BRLI No. 1 Acquisition Corp., a New Jersey corporation
(the  "Purchaser"),  each with its principal  place of business at 481 Edward H.
Ross Drive, Elmwood Park, New Jersey 07407.

                             W I T N E S S E T H :

      WHEREAS RBF is engaged in the  manufacture of certain health food products
at its leased facility at 118 Jackson  Avenue,  Syosset,  Long Island,  New York
11791 and in the distribution of such products under the name "Right Body Foods"
in the greater New York metropolitan area (the "Health Food Business"); and

      WHEREAS  the  Sellers  desire to sell and  Purchaser  desires to  purchase
certain assets used by RBF in its operation of the Health Food Business so as to
enable Purchaser to operate the Health Food Business; and

      WHEREAS  Purchaser is unwilling to effect such purchase  unless it is able
to employ  Klafter to serve as Director of the Health Food  Business  operations
and to obtain  Klafter's  agreement not to compete with Purchaser and/or BRLI in
its operation of the Health Food Business.

      NOW,  THEREFORE,  in  consideration of the mutual covenants and agreements
hereinafter  contained  and other good and valuable  consideration,  the receipt
whereof and sufficiency of which are hereby acknowledged, it is hereby agreed as
follows:

1.    Purchase and Sale

      (a) At the Closing  (hereinafter  defined)  Sellers  will sell,  transfer,
convey,  grant,  relinquish,  release,  assign,  and deliver to  Purchaser,  and
Purchaser  will purchase and acquire from  Sellers,  on the terms and subject to
the conditions set forth in this Agreement, certain assets and rights of Sellers
related to the Health Food  Business  as they exist as of the Closing  including
Sellers'  rights  to the  tradename  "Right  Body  Foods  Inc." and to all other
registered or unregistered  patents,  trademarks  and/or  tradenames,  licenses,
recipes,  labels,  artwork,  food  ingredients,   supplies,  certain  equipment,
leaseholds, customer lists and


<PAGE>



associated  goodwill  used in the  operation  of the Health  Food  Business  and
certain other  assets,  all of which are  specifically  enumerated on Schedule A
hereto and are hereafter referred to as the "Assets."

      (b) At the Closing,  BRLI shall issue an aggregate  180,000  shares of its
authorized but unissued  common stock and deliver same to Purchaser,  registered
in the name of RBF, or if RBF so designates,  in the name of Klafter, which upon
delivery  to the  registered  owner  together  with  BRLI  and  the  Purchaser's
assumption of the liabilities  enumerated in Schedule B hereto, shall constitute
full payment for the Assets.

      (c)  Excluded  from this  sale and  purchase  are any and all  liabilities
(including but not limited to tax  liabilities of the Sellers)  except for those
liabilities  specifically enumerated on Schedule B hereto which shall be assumed
by the Purchaser.

      (d) At the Closing, BRLI shall issue an aggregate 20,000 additional shares
of its  authorized  but unissued  common  stock and deliver  same to  Purchaser,
registered  in Klafter's  name,  for delivery to Klafter in full payment for her
non-competition agreement.

2.    The Closing

      (a) The closing of the sale and purchase (the "Closing")  shall take place
at the principal  offices of the  Purchaser on Tuesday,  December 14, 1999 or at
such date and time  thereafter  as the parties  hereto shall  mutually  agree in
writing (the "Closing Date").

      (b) At the Closing, Sellers shall deliver or cause to be
delivered to the Purchaser;

            (i) a duly  executed  bill  of  sale  substantially  in the  form of
Schedule C hereto ("Bill of Sale") and other good and sufficient  instruments of
transfer and conveyance,  including assignments if appropriate, as shall vest in
Purchaser all of Sellers' rights,  title and interest in and to the Assets, free
from all encumbrances;

            (ii) a duly executed  assignment to Purchaser of the exclusive right
to use of all of Sellers'  registered and unregistered  patents,  trademarks and
tradenames including the right to the name "Right Body Foods";

            (iii) an employment agreement (the "Employment
Agreement") in the form of Schedule D hereto, duly executed by
Klafter;


                                      2

<PAGE>



            (iv) a non-competition agreement (the "Non-Competition
Agreement") in the form of Schedule E hereto, duly executed by
Klafter;

            (v) a duly  executed  assignment  of the  lease of the  Premises  in
Syosset,  Long Island,  New York  utilized by RBF in the operation of the Health
Food Business to Purchaser  and a duly  executed  consent from the Landlord with
respect to such assignment;

            (vi) an investment  representation  letter substantially in the form
of  Schedule F hereto,  with  respect to the shares of BRLI  common  stock to be
issued at the Closing, duly executed by the recipient(s) of such shares; and

            (vii)  all  such  other  duly  executed  assignments  and  consents,
satisfactory  in  form  and  content  to the  Purchaser,  as the  Purchaser  may
reasonably  require  in  order  to  effectuate  transfer  of the  Assets  to the
Purchaser.

      (c) At the Closing, the Purchaser shall deliver or cause to be
delivered to RBF and/or Klafter, as the case may be;

            (i) a duly  executed  assumption  of certain  liabilities  agreement
substantially  in  the  form  of  Schedule  G  hereto  ("Assumption  of  Certain
Liabilities  Agreement")  as shall be binding  upon both BRLI and the  Purchaser
with respect to those liabilities of RBF specifically enumerated on Schedule B;

            (ii) an aggregate  180,000 shares of BRLI's  authorized but unissued
common stock to RBF, or if RBF so designates in writing, to Klafter,  registered
in the  recipient's  name,  in full payment  (together  with the  Assumption  of
Certain Liabilities Agreement) for the Assets;

            (iii) the Employment Agreement, duly executed by BRLI;

            (iv) the Non-Competition Agreement, duly executed by BRLI
and the Purchaser;

            (v) an aggregate  20,000  shares of BRLI's  authorized  but unissued
common stock to Klafter,  registered in Klafter's  name, in full payment for her
execution and delivery of the Non-Competition Agreement;

            (vi) an  assumption  by  Purchaser  of the lease for the Premises in
Syosset,  Long Island,  New York and a guarantee of the Purchaser's  obligations
thereunder executed by BRLI; and

            (vii) all such other duly executed consents and
assumptions satisfactory in form and content to the Sellers, as the

                                      3

<PAGE>



Sellers may reasonably require in order to consummate the transactions described
herein.

3.    Representations and Warranties of Sellers

      (a) As an  inducement  to  Purchaser  to enter  into  this  Agreement  and
consummate the transactions  contemplated hereby, the Sellers, and each of them,
jointly and severally, represent and warrant to BRLI and the Purchaser that:

            (i) RBF is a corporation  duly  organized,  validly  existing and in
good  standing  under  the laws of the  State of New York and has all  requisite
power and authority to enter into this Agreement, to consummate the transactions
herein contemplated,  and to own, lease and operate its properties. They have no
actual  knowledge of any impairment of RBF's power and authority to carry on the
Health Food business as it is now being conducted.

            (ii) The execution and delivery of this Agreement,  the consummation
of the transactions  herein  contemplated  and the  performance,  observance and
fulfillment by RBF of all of the terms and  conditions  hereof on its part to be
performed,  observed, and fulfilled, (a) have been duly approved and effectively
authorized by the Board of Directors and by the sole  stockholder  of RBF and no
other  proceedings are necessary to authorize this Agreement or the consummation
of the  transactions  contemplated  hereby,  (b) do not  and  will  not  (either
immediately or with the lapse of time, or with notice,  or both) (1) violate any
provisions of any judicial or administrative  order,  award,  judgment,  decree,
statute,  rule or  regulation  applicable to RBF or any of its  properties,  (2)
conflict with or result in a breach of, constitute a default under,  contravene,
result in a  forfeiture  of a right  under,  or result  in the  acceleration  of
payment or performance under, any note, bond, mortgage,  indenture, deed, trust,
license,  lease,  agreement, or other instrument or obligation to which RBF is a
party or by which  RBF or any of the  Assets  may be bound or  affected,  or (3)
result in the creation or imposition of any lien,  security interest,  charge or
other encumbrance against any of the Assets.

            (iii)  This  Agreement  has  been  duly  and  validly  executed  and
delivered by the Sellers and upon execution and delivery, will constitute valid,
binding  and  enforceable  obligations  of the  Sellers  subject to  bankruptcy,
insolvency and similar laws affecting  creditors rights generally and subject to
general  principles of equity.  No petition in  bankruptcy  has been filed by or
against either of the Sellers. The Sellers have the right, power, legal capacity
and authority to enter into and perform their  obligations  under this Agreement
(and with respect to Klafter, her obligations under the Employment Agreement and
the  Non-Competition  Agreement)  and no consent of any third party is necessary
with respect thereto which has not been obtained.

                                      4

<PAGE>



            (iv)  There  is no  material  action,  dispute,  claim,  litigation,
arbitration,  investigation,  or other proceeding,  at law or in equity or by or
before any court or  governmental  or  administrative  body (U.S.  or  foreign),
pending or threatened  against RBF, its business or properties,  or with respect
to the  transactions  contemplated by this Agreement,  and RBF is not subject to
any adverse judicial,  governmental or agency judgment,  decree or order, nor do
the Sellers know of any basis for any such action, dispute,  claim,  litigation,
arbitration, investigation or other proceeding.

            (v) RBF has made, and will continue to make,  adequate provision for
payment of its  obligations,  and RBF is not in default of and will not with the
passage of time or  otherwise  become in default  of, any  current or  long-term
liabilities   (including   contingent   liabilities),   debts  or   obligations,
contractual or otherwise.

            (vi)  Immediately  after the Closing,  RBF will cease all operations
relating to the Health Food Business and will engage  solely in  collecting  any
receivables  outstanding  on the Closing  Date and paying all payables and other
obligations which are not expressly assumed hereunder by BRLI and the Purchaser.
RBF  shall  be  permitted  to  maintain  a  bank  account  for  such   purposes.
Furthermore,  RBF will not  engage  in any  facet of the  Health  Food  Business
anywhere in the continental  United States east of the  Mississippi  River for a
period of five (5) years after the Closing.

            (vii)  Annexed   hereto  as  Schedule  H  is  a  copy  of  the  sole
governmental  license which RBF has obtained in connection with its operation of
the Health Food Business.  Sellers have no actual knowledge that said license is
not in full force and effect.

            (viii) Annexed  hereto as Schedule I is a schedule  listing each and
every inspection or other visit to RBF's premises by any federal, state or local
governmental  organization  or  authority  which is or was related to the Health
Food Business  including (a) the date of such inspection or visit;  (b) the name
of the organization or authority;  (c) the substance of the  communication  from
the  organization or authority after such visit;  and (d) the responsive  action
(if any) taken by RBF.

            (ix) Since its inception,  the food products sold and/or distributed
by RBF in its operation of the Health Food Business have been tested for quality
by independent  testing  entities and RBF has not received any negative  reports
concerning such tests.

            (x) From August 31, 1999 through the date hereof,  there has been no
material  adverse  change in RBF's  financial  condition,  operating  results or
business, and no sale or distribution of

                                      5

<PAGE>



assets and no incurrence of liabilities or indebtedness, except in each case, in
the ordinary course of its business.

            (xi) As soon as possible after the Closing but no later than two (2)
weeks  after  the  Closing,  RBF  will  file a duly  executed  amendment  to its
certificate of incorporation with the New York Department of State, changing its
name from "Right Body Foods, Inc."

      (b) The  foregoing  representations  and  warranties  are  made  with  the
knowledge  and  expectation  that the  Purchaser  is placing  complete  reliance
thereon.

4.    Representations and Warranties of BRLI and Purchaser
      ----------------------------------------------------

      (a) As an  inducement  to the  Sellers  to enter into this  Agreement  and
consummate the transactions contemplated hereby, BRLI and Purchaser, and each of
them, represent and warrant:

            (i) BRLI and Purchaser are each corporations duly organized, validly
existing and in good standing under the laws of the State of New Jersey and each
has all requisite corporate power and authority to enter into this Agreement, to
consummate the transactions herein  contemplated,  to own, lease and operate its
properties and to carry on its business as it is now being  conducted,  and each
is  duly  licensed,  authorized  and  qualified  to do  business  and is in good
standing  in all  jurisdictions  in which the  conduct  of its  business  or the
ownership  or  leasing  of  its  properties  requires  it to  be  so  qualified,
authorized or licensed.

            (ii) The execution and delivery of this Agreement,  the consummation
of the  transactions  herein  and  therein  contemplated  and  the  performance,
observance  and  fulfillment  by BRLI and by  Purchaser  of all of the terms and
conditions hereof and thereof, on each of their parts to be performed, observed,
and fulfilled, (A) have all been approved and effectively authorized by BRLI and
by Purchaser's  boards of directors and no other proceedings on the part of BRLI
or of Purchaser are necessary to authorize this Agreement or the consummation of
the  transactions  contemplated  hereby  and  thereby,  (B) do not and  will not
(either  immediately  or with the lapse of time,  or with  notice,  or both) (1)
conflict with any of the provisions of the Articles of  Incorporation or by-laws
of  BRLI  or  of   Purchaser,   violate  any   provisions  of  any  judicial  or
administrative  order,  award,  judgment,  decree,  statute,  rule or regulation
applicable to BRLI or Purchaser or any of their properties, (2) conflict with or
result in a breach  of,  constitute  a default  under,  contravene,  result in a
forfeiture  of a right  under,  or  result in the  acceleration  of  payment  or
performance under, any note, bond, mortgage,  indenture,  deed, trust,  license,
lease,  agreement,  or other instrument or obligation to which BRLI or Purchaser
is a party or by which BRLI or Purchaser or any of

                                      6

<PAGE>



their  properties  may be bound or  affected,  or (3) result in the  creation or
imposition of any lien,  security interest,  charge or other encumbrance against
any properties of BRLI or Purchaser.

            (iii)  This  Agreement  has  been  duly  and  validly  executed  and
delivered  by BRLI  and by  Purchaser  and upon  execution  and  delivery,  will
constitute  valid,  binding and  enforceable  obligations of BRLI and Purchaser.
BRLI and the Purchaser each has the right,  power,  legal capacity and authority
to enter into and perform its obligations under this Agreement and no consent of
any third party is necessary with respect thereto,  which has not been obtained.
No petition in bankruptcy has been filed by or against or is  contemplated to be
filed by BRLI or the Purchaser.

            (iv)  There  is no  material  action,  dispute,  claim,  litigation,
arbitration,  investigation,  or other proceeding,  at law or in equity or by or
before any court or  governmental  or  administrative  body (U.S.  or  foreign),
pending or threatened against BRLI or the Purchaser, or against their businesses
or  properties,  or  with  respect  to the  transactions  contemplated  by  this
Agreement,  and  neither  BRLI  nor the  Purchaser  is  subject  to any  adverse
judicial, governmental or agency judgment, decree or order, nor does BRLI or the
Purchaser  know of any basis for any such action,  dispute,  claim,  litigation,
arbitration, investigation or other proceeding.

            (v) At the  Closing  Date,  BRLI will  have not more than  8,000,000
shares of its common stock, $.01 par value,  issued and outstanding,  each share
of which  is  entitled  to one vote on all  matters  on which  stockholders  are
entitled to vote. In addition, at such date, the only other outstanding class of
BRLI  capital  stock  will be Series A Senior  Preferred  Stock,  $.10 par value
("Senior  Preferred Stock") of which 604,078 shares were issued and outstanding.
Each share of Senior  Preferred  Stock is entitled to one vote on all matters on
which  stockholders  are  entitled  to vote.  Furthermore,  each share of Senior
Preferred  Stock is  convertible  into one share of common stock at a conversion
price of $.75.

      (b) The  foregoing  representations  and  warranties  are  made  with  the
knowledge  and  expectation  that the  Sellers  are  placing  complete  reliance
thereon.

5.    Indemnification

      (a)  Provided  that the  representations  made by BRLI and by Purchaser in
this Agreement are accurate and BRLI and Purchaser are in compliance  with their
obligations  under this  Agreement,  the Sellers  and each of them,  jointly and
severally  hereby agree to indemnify and hold harmless BRLI and  Purchaser,  and
each of them, against and in respect of:


                                      7

<PAGE>



            (i) all  liabilities  and  obligations  of, or claims  against  BRLI
and/or  the  Purchaser  based  on  liabilities  and  obligations  of  RBF or the
individual Seller in connection with the operation up to the Closing Date of the
Health Food Business, including but not limited to liabilities (if any) based on
alleged violations of food processing, licensing and/or labeling laws as well as
liabilities  for  income,  employment,  sales  and all  other  taxes  as well as
penalties and interest thereon (if any);  unless same shall result from the acts
or omissions of BRLI and/or the  Purchaser or are  liabilities  of RBF expressly
assumed hereunder by BRLI and/or the Purchaser;

            (ii)  any  damage  or   deficiency   resulting   from  any  material
misrepresentation,  breach of warranty or nonfulfillment of any agreement on the
part  of  any  of  the  Sellers  under  this  Agreement  or  from  any  material
misrepresentation  in or  omission  from any  certificate  or  other  instrument
furnished or to be furnished to Purchaser under this Agreement; and

            (iii)  all  actions,  suits,  proceedings,   demands,   assessments,
judgments, costs and expenses incident to any of the foregoing.

      (b)  Provided  that  the  representations  made  by the  Sellers  in  this
Agreement  are  accurate  and  each  Seller  is in  compliance  with its and her
obligations  under  this  Agreement,  BRLI and the  Purchaser,  and each of them
hereby  agrees to  indemnify  and hold  harmless  the  Sellers and each of them,
against and in respect of:

            (i) all  liabilities  and  obligations  of,  or claims  against  the
Sellers or any of them with respect to the Assets, for periods after the Closing
as a result of Purchaser's  purchase of the Assets  hereunder  unless same shall
result from the acts or omissions of Sellers;

            (ii)  any  damage  or   deficiency   resulting   from  any  material
misrepresentation, breach of warranty, or nonfulfillment of any agreement on the
part of Purchaser under this Agreement or from any material misrepresentation in
or  omission  from  any  certificate  or  other  instrument  furnished  or to be
furnished to Sellers under this Agreement; and

            (iii)  all  actions,  suits,  proceedings,   demands,   assessments,
judgments, costs and expenses incident to any of the foregoing.

      (c) In the event that any parties hereunder (the  "Indemnitees")  elect to
assert their rights  pursuant to this Section 5 to  indemnification  against the
other parties hereto (the "Indemnitors"), prior to settling or defending against
any claim as to which they may seek indemnification hereunder, the Indemnitees

                                      8

<PAGE>



shall give notice to the Indemnitors of such election and the claim with respect
to which  indemnification is sought. The Indemnitors shall have the right within
seven (7) days after such notice,  time being of the essence,  to give notice to
the  Indemnitees  that they elect to  contest  such  claim and  thereupon,  upon
posting reasonably  adequate security with the Indemnitees,  will be entitled at
their own expense,  to contest  same.  In the event they so elect to contest the
claim,  the  Indemnitors  will also  have the right to settle  same at their own
expense with the  Indemnitees'  consent,  which consent will not be unreasonably
withheld.

6.    Expenses

      Each of the parties shall pay its or her own expenses  (including  without
limitation,  the fees and expenses of the agents,  representatives,  counsel and
accountants) incidental to the preparation and consummation of this Agreement.

7.    Brokerage

      Each party shall  indemnify  and hold the other  parties free and harmless
from all losses,  damages,  costs, and expenses (including attorney's fees) that
may be  suffered as a result of claims  brought by any broker or finder  seeking
compensation on account of this  transaction  arising out of the actions of such
party.

8.    Survival of Representations and Warranties

      The parties agree that the representations,  warranties,  agreements,  and
covenants  contained in this  Agreement or in any other  documents  delivered in
accordance  with or by virtue of this Agreement  shall survive the execution and
delivery of this Agreement and all other  instruments in connection  herewith or
therewith.

9.    Notices

      All notices and other documents required or permitted to be given pursuant
to this Agreement  shall be in writing and shall be deemed to have been given if
delivered  by hand with an  acknowledgement  of  receipt  therefor  or mailed by
registered or certified mail,  return receipt  requested,  to the parties at the
addresses  provided  above  (or  such  other  address  for a party  as  shall be
specified by notice given pursuant to this  paragraph)  with a copy by certified
mail, return receipt  requested,  to the attorneys for the respective parties at
the following  addresses:  for Sellers - Vitale & Levitt,  445 Broadhollow Road,
Suite 124,  Melville,  New York 11747 and for BRLI and the  Purchaser - Tolins &
Lowenfels, A Professional  Corporation,  12 East 49th Street, New York, New York
10017.


                                      9

<PAGE>



10.   Binding Effect and Assignability

      This Agreement shall be binding upon and shall inure to the benefit of the
parties hereto and their respective successors, heirs and assigns.

11.   Governing Law and Jurisdiction

      This Agreement shall be construed and enforced in accordance with the laws
of the State of New Jersey  without  regard to the  principle of the conflict of
laws. The parties hereto consent to the in personam  jurisdiction  of the courts
of the State of New Jersey and  further  agree that any action  with  respect to
this  Agreement  shall be commenced  and  prosecuted  only in such  courts.  The
parties  hereby waive trial by jury in any action or  proceeding  arising  under
this Agreement.

12.   Remedies

      No remedy herein  conferred  upon or reserved to a party is intended to be
exclusive of any other available remedy, but each and every such remedy shall be
cumulative  and in addition to every other remedy given under this  Agreement or
in connection  with this  Agreement  and now or hereafter  existing at law or in
equity.

13.   Entire Agreement

      This  Agreement,   the  Employment  Agreement  and  the  Non-  Competition
Agreement  constitute the entire agreement among the parties with respect to the
subject matter  contained herein and therein and supersedes all prior agreements
and  understandings,  oral or written.  This Agreement and such other Agreements
may not be amended or modified except in writing executed by each of the parties
hereto and thereto.

14.   Confidentiality of Agreement and Disclosure

      The parties agree that the terms of this  Agreement  and the  transactions
contemplated  hereby will be kept confidential and not publicly  disclosed until
such time and in such manner as shall be determined by the  Purchaser,  although
Klafter shall be permitted to disclose the terms of the  transaction  to members
of her immediate family and her professional advisors.



                                      10

<PAGE>



     IN WITNESS WHEREOF, the parties have executed this Agreement on the day and
year first above written.



                              /s/Rebecca Klafter
                              ------------------
                              Rebecca Klafter (individually)

                              Right Body Foods Inc.


                                    By /s/Rebecca Klafter
                                  Rebecca Klafter, President

                        Bio-Reference Laboratories, Inc.


                              By /s/Howard Dubinett
                            Howard Dubinett, Executive Vice President


                        BRLI No. 1 Acquisition Corp.



                              By /s/Howard Dubinett
                            Howard Dubinett, Executive Vice President



                                      11





                                 Exhibit 10.10

                             EMPLOYMENT AGREEMENT


      AGREEMENT  made this 14th day of December  1999,  by and  between  Rebecca
Klafter  having an  address  at 102  Bristol  Drive,  Woodbury,  New York  11797
(hereinafter  referred to as the  "Employee")  and Bio- Reference  Laboratories,
Inc., a New Jersey  corporation with principal  offices located at 481 Edward H.
Ross Drive,  Elmwood  Park,  New Jersey  07407  (hereinafter  referred to as the
"Company").
                                  WITNESSETH:

      WHEREAS,  the Company is a New Jersey Corporation  engaged in the clinical
laboratory business; and

      WHEREAS,  the Employee is the chief executive officer and sole stockholder
of Right Body Foods Inc., a New York  corporation  engaged in the manufacture of
certain  health food  products at its facility at 118 Jackson  Avenue,  Syosset,
Long Island, New York 11791 ("RBF") and the distribution of such products in the
greater New York metropolitan area (the "Health Food Business"); and

      WHEREAS, the Company has agreed through its wholly-owned subsidiary,  BRLI
No. 1 Acquisition  Corp.  ("BRLI Acq. Corp.") to purchase certain assets used by
RBF in its operation of the Health Food Business so as to enable BRLI Acq. Corp.
to operate the Health Food Business; and



<PAGE>



      WHEREAS,  the Company is  unwilling to effect such  purchase  unless it is
able to employ the  Employee to serve as  Director  of the Health Food  Business
operations  of BRLI Acq.  Corp.  and to obtain the  Employee's  agreement not to
compete with the Company  and/or BRLI Acq.  Corp. in the operation of the Health
Food Business; and

      WHEREAS,  the Employee  desires to commence  employment  with the Company,
pursuant to the terms and conditions  herein set forth,  superseding any and all
prior  agreements,  express or implied,  between the Company,  its  subsidiaries
and/or predecessors and the Employee;

      NOW THEREFORE,  it is mutually agreed by and between the parties hereto as
follows:



                                   ARTICLE I
                                  EMPLOYMENT
      Subject  to and upon the  terms  and  conditions  of this  Agreement,  the
Company  hereby  employs the  Employee,  and the  Employee  hereby  accepts such
employment in her capacity as Director of the Health Food Business operations of
BRLI Acq.  Corp.  The  Company  agrees  that  during the term of her  employment
hereunder, the Employee will be consulted with by the president and/or the

                                      2

<PAGE>



executive vice president of the Company with regard to and will be provided with
the  opportunity to review each recipe as well as each proposed change in recipe
with respect to each food product  manufactured  and  distributed  by the Health
Food Business.
      Employee   represents  and  warrants  that  there  is  no  restriction  or
impediment,  contractual  or  otherwise  to her  accepting  such  employment  as
provided for herein,  and that she is not in breach or violation of any covenant
or agreement with any party relating to her employment.  Employee represents and
warrants,  and covenants and agrees that in entering  into  employment  with the
Company  and in the  performance  of her duties  that she is not  utilizing  any
secret or confidential information of any other person.

                                  ARTICLE II
                                    DUTIES
      (A) The Employee shall, during the continuation of her employment with the
Company,  and  subject  to the  direction  and  control of the  Company's  Chief
Executive  Officer and Chief  Operating  Officer,  perform  such  executive  and
marketing  duties  and  functions  as she may be called  upon to perform by such
executive officers during the terms of this Agreement principally on Long Island
in the State of New York but also in the State of New Jersey.
      (B) During the  continuation  of her  employment,  the Employee  agrees to
devote her full time to the  performance  of her duties for the  Company  and to
render such services for any subsidiary or

                                      3

<PAGE>



affiliate  corporation of the Company  including  BRLI Acq. Corp.  provided that
from the date hereof through  December 31, 1999, the Employee shall be permitted
to render her services  hereunder on a part-time basis provided that she devotes
a minimum of 25 hours per five-day  week  (pro-rated  for partial  weeks) to the
performance of her duties hereunder.
      (C) The Employee  shall  perform to the best of her ability the  following
services  and  duties  for  the  Company  and  its   subsidiary   and  affiliate
corporations (by way of example, and not by way of limitation):

      (i) Those duties  attendant to the position with the Company and BRLI Acq.
Corp. for which she is being hired, including the establishment,  supervision of
manufacturing and marketing of products for the Health Food Business;

      (ii)  Assisting  the  Company  and BRLI Acq.  Corp.  in the  planning  and
implementation of all sales promotion,  advertising, public relations, personnel
and product development programs for the Health Food Business;

      (iii) Promotion of the relationships of the Company and its subsidiary and
affiliate   corporations   including  BRLI  Acq.  Corp.  with  their  respective
employees, customers, suppliers and others in the business community.

      (iv) Working with the Company's and BRLI Acq. Corp.'s  professional  staff
toward the  development  of  special  programs  to offer  Health  Food  Business
products and services to physicians and healthcare facilities.

                                      4

<PAGE>




                                  ARTICLE III
                                 COMPENSATION
      Solely during the time that this Employment Agreement is in full force and
effect,  the Company shall make the following payments to the Employee and shall
provide her with the following  benefits as compensation for all of her services
rendered hereunder.
      (A) Salary - initially at the rate of $150,000 per annum (the "Annual Base
Salary"),  payable in weekly  installments or pursuant to the Company's  regular
pay periods.  For each successive twelve- month period that this Agreement is in
effect beginning with the twelve-month  period commencing  November 1, 2000, the
Annual Base Salary in effect  immediately prior to such November 1 date shall be
increased (but never  decreased) by the same percentage  increase as that of the
percentage  increase in the  Consumer  Price Index -- All Items for the New York
metropolitan  area for the month of November in the  successive  period over the
first month of the twelve-month or shorter fiscal period then ended.
      (B)  Signing  Bonus  - in the  aggregate  amount  of  $100,000  paid in 24
consecutive   equal  monthly   installments  of  $4,166.67,   without  interest,
commencing February 1, 2000.
      (C)  Commission  Bonus and Bonus  Guarantee - The Employee  will be paid a
"Commission  Bonus" in an amount equal to the following  percentages  of the net
cash receipts (net of required credits and refunds) during the period commencing
on the date hereof and ending

                                      5

<PAGE>



on October 31, 2000 and during each  successive  twelve-month  period,  actually
collected by the division or subsidiary of the Company  organized to operate the
Health Food Business, which receipts are attributable to such business:

      Collected Cash Receipts                         Bonus-Percentage of the
      In excess of               Not more than       Collected Net Cash Receipts
      ------------               -------------       -------------------------

           --                      $ 1,000,000                   None
        $ 1,000,000                $ 5,000,000                    5%
        $ 5,000,000                $10,000,000                    2%
        $10,000,000                $20,000,000                    1%

      By way of example,  if the net cash receipts (net of required  credits and
refunds) of the Health Food  Business  actually  collected  during an applicable
period  totalled  $7,500,000,  the Commission  Bonus with respect to such period
would be  $250,000  ($0 +  $200,000  +  $50,000)  subject to offset by the Bonus
Guarantee  hereinafter  described.  No net cash  receipts  collected  during one
period  shall be carried  back or forward  to a prior or  subsequent  period for
purposes  of  computing  the  Commission  Bonus  with  respect  to such prior or
subsequent period.  Each Commission Bonus shall be paid within 60 days after the
close of each such period. The Company agrees that the Health Food Business will
be operated  through BRLI Acq.  Corp. The Company agrees to provide the Employee
and her agents with access to the books and records of the Health Food  Business
on a  quarterly  basis  during  normal  business  hours in order to  verify  the
"Collected Cash Receipts" of the Health Food Business.

                                      6

<PAGE>



      With respect to the initial period only  commencing on the date hereof and
ending on October 31, 2000 (the "First Bonus  Period"),  the Employee shall also
be paid a $50,000 non-refundable "Bonus Guarantee" against her Commission Bonus.
Such  Bonus  Guarantee  shall  be  paid  in  twelve  consecutive  equal  monthly
installments of $4,166.66,  without  interest,  commencing  February 1, 2000 but
shall be credited  solely  against the Employee's  Commission  Bonus earned with
respect to the First Bonus Period.  By way of example,  if the net cash receipts
of the Health Food  Business  actually  collected  during the First Bonus Period
totalled  $1,800,000,  the Employee  will be entitled to retain her entire Bonus
Guarantee  of  $50,000  as it is  non-refundable  but  would  not  be  paid  any
Commission  Bonus with  respect to such  period as the $50,000  Bonus  Guarantee
exceeds the $40,000  Commission  Bonus to which she would otherwise be entitled.
If such net cash receipts during the First Bonus Period totalled $5,500,000, the
Employee would be paid a $160,000  Commission  Bonus ($210,000  Commission Bonus
less $50,000  Bonus  Guarantee)  but would also be entitled to retain her entire
Bonus Guarantee of $50,000 as it is non-refundable.
      (D) Other  Benefits - The Company  will  provide the  Employee  with three
weeks of paid vacation for each  approximately 12 month period ending October 31
commencing  with the period  ending  October 31, 2000,  on such dates as she may
elect, as well as  participation  on an equitable  basis in any medical,  health
benefit or other employee benefit plan established for senior  management of the
Company. The Company will provide the Employee with a $500 per

                                      7

<PAGE>



month  automobile  allowance  towards lease or purchase and  insurance  coverage
costs and will  reimburse  the Employee  upon  presentation  of the  appropriate
vouchers for business and travel expenses  incurred by the Employee on behalf of
the Company as well as for reasonable  maintenance and repairs of the automobile
used by the Employee in connection with the Health Food Business.
      (E) Key-Man  Life  Insurance  - In the event the Company  wishes to obtain
"Key-Man"  Life  Insurance  on the  life of the  Employee,  Employee  agrees  to
cooperate  with the Company in completing any  applications  necessary to obtain
such insurance and to promptly submit to such physical  examinations and furnish
such  information  as any  proposed  insurance  carrier may  request,  providing
Employee is insurable.

                                  ARTICLE IV
                             TERM AND TERMINATION
      The term of this Agreement shall be for a period of approximately five (5)
years commencing on the date hereof and terminating on October 31, 2004.
      The  Company,  at its option,  exercised  in writing not less than 30 days
prior to the end of such term (the "Initial Term"), may elect to extend the term
of this Agreement for an additional  twelve-month  period terminating on October
31, 2005 (the "First Extension Year"). In the event of such election, all of the
terms and  conditions  of this  Agreement  shall remain in full force and effect
except that (a) the Employee's Annual Salary in effect at

                                      8

<PAGE>



the end of the Initial  Term shall be increased by 10% but shall not be modified
by changes in the Consumer  Price Index;  (b) the Employee shall not be entitled
to an additional  Signing Bonus or a Bonus  Guarantee;  but (c) the terms of the
Commission Bonus shall remain in full force and effect.
      If the Company so extends the Initial Term for a First  Extension Year, it
may at its option, exercised not less than 30 days prior to the end of the First
Extension  Year,  extend  the term of this  Agreement  for a  second  additional
twelve-month  period  terminating  on October  31, 2006 (the  "Second  Extension
Year").  In the event of such election,  all of the terms and conditions of this
Agreement  shall remain in full force and effect except that (a) the  Employee's
Annual  Salary  during the Second  Extension  Year shall  remain the same as her
Annual  Salary  in  effect  during  the  First  Extension  Year and shall not be
modified by changes in the Consumer  Price Index;  (b) the Employee shall not be
entitled to an additional Signing Bonus or a Bonus Guarantee;  but (c) the terms
of the Commission Bonus shall remain in full force and effect.
      The Company shall have the right to terminate  this  Agreement upon twenty
(20) days prior  written  notice to the Employee  for "cause,"  defined as gross
dereliction  of  duty,  gross  negligence  affecting   Employee's   performance,
conviction of a "crime," or substantial violation of the terms of this Agreement
provided  that prior to the  expiration  of such twenty (20) day period,  if the
Employee  is able to and  cures  such  "cause,"  such  termination  will  not be
effective. For purposes of this Agreement, "crime" is

                                      9

<PAGE>



defined as a felony or a crime of high moral turpitude,  but in no event shall a
traffic  offense or an offense  which is  considered  to be a disorderly  person
offense or a  misdemeanor  be deemed a "crime"  permitting  termination.  In the
event of termination of this Agreement "for cause," no unpaid or future payments
required  hereunder  including payments of Annual Salary, the Signing Bonus, the
Commission  Bonus and/or the Bonus Guarantee shall be required to be paid to the
Employee after such termination date.

                                   ARTICLE V
                NON-DISCLOSURE OF INFORMATION AND TRADE SECRETS

      Employee  acknowledges  that BRLI Acq. Corp. has purchased  certain secret
information  relating to the Health Food Business  including  business plans and
programs,  marketing plans, contractual arrangements with others,  formulations,
recipes and customer lists and that in the course of her duties  hereunder,  the
Company  and/or  BRLI Acq.  Corp.  will make  available  to her and she may also
develop additional secret information of like nature relating to the Health Food
Business. All of such secret information whether purchased by BRLI Acq. Corp. or
developed  during  the  course of her  employment  is  hereinafter  collectively
referred to as the "Proprietary Information." Employee waives any and all rights
to the  Proprietary  Information and agrees that all such rights shall be vested
solely  in the  Company  and BRLI  Acq.  Corp.  even  after  termination  of her
employment. Upon the termination of employment,  Employee shall promptly deliver
all correspondence, notes, reports, programs,

                                      10

<PAGE>



proposals,  formulations,  recipes, customer lists and books and records, or any
other documents,  and all copies thereof,  relating to the Health Food Business,
to BRLI Acq. Corp. (The Company and BRLI Acq. Corp. have entered into a separate
Non-Competition Agreement with the Employee as of the date hereof.)

                                  ARTICLE VI
                                 SEVERABILITY
      If any provision of the Agreement shall be held invalid and unenforceable,
the remainder of this  Agreement  shall remain in full force and effect.  If any
provision  is  held  invalid  or   unenforceable   with  respect  to  particular
circumstances,   it  shall  remain  in  full  force  and  effect  in  all  other
circumstances.

                                  ARTICLE VII
                                    NOTICES

      All notices  required to be given under the terms of this Agreement  shall
be in writing and shall be deemed to have been duly given only if  delivered  to
the addressee in person or mailed by certified mail,  return receipt  requested,
as follows:

IF TO COMPANY:           Bio-Reference Laboratories, Inc. (or BRLI Acq.
Corp.)
 AND/OR TO              481 Edward H. Ross Drive
BRLI ACQ. CORP.         Elmwood Park, New Jersey 07407
                        Attn: Howard Dubinett, Executive Vice President


WITH COPY TO:           Roger Tolins, Esq.
                        Tolins and Lowenfels
                        12 East 49th St - 21st Floor
                        New York, New York 10017

                                      11

<PAGE>



IF TO EMPLOYEE:          Rebecca Klafter
                         102 Bristol Drive
                         Woodbury, New York 11797

WITH COPY TO:            Paul Levitt, Esq.
                         Vitale & Levitt
                         445 Broadhollow Road, Suite 124
                         Melville, New York 11747

or such other additional address as the party to receive the notice shall advise
by due notice in accordance with this paragraph.

                                 ARTICLE VIII
                                    BENEFIT
      This agreement  shall inure to, and be binding upon,  the parties  hereto,
the  successors  and  assigns  of  the  Company,  and  the  heirs  and  personal
representatives of the Employee.

                                  ARTICLE IX
                                    WAIVER
      The waiver by either party of any breach or violation of any  provision of
this  Agreement  shall not operate or be construed as a waiver of any subsequent
breach of construction and validity.

                                   ARTICLE X
                                 GOVERNING LAW
      This Agreement shall be construed and enforced in accordance with the laws
of the State of New Jersey  without  regard to the  principle of the conflict of
laws. The parties hereto consent to the in personam  jurisdiction  of the courts
of the State of New

                                      12

<PAGE>



Jersey and further agree that any action with respect to this Agreement shall be
commenced and prosecuted only in such courts.  The parties hereby waive trial by
jury in any action or proceeding arising under this Agreement.

                                  ARTICLE XI
                                 JURISDICTION
      In case any provision of this Agreement shall be invalid under the laws of
any county,  state or  jurisdiction,  such invalidity shall not affect any other
provisions of this Agreement.

                                  ARTICLE XII
                                   REMEDIES
      No remedy herein  conferred  upon or reserved to a party is intended to be
exclusive of any other available remedy, but each and every such remedy shall be
cumulative  and in addition to every other remedy given under this  Agreement or
in connection  with this  Agreement  and now or hereafter  existing at law or in
equity.

                                 ARTICLE XIII
                               ENTIRE AGREEMENT
      This Agreement, the Non-Competition  Agreement and the Asset/Sale Purchase
Agreement  constitute the entire agreement among the parties with respect to the
subject matter  contained herein and therein and supersedes all prior agreements
and  understandings,  oral or written.  This Agreement and such other Agreements
may not

                                      13

<PAGE>


be amended or modified except in writing  executed by each of the parties hereto
and thereto.

      IN WITNESS WHEREOF,  the parties have hereto set their hands and seals the
day and year written below their names.

      Signed, sealed and delivered in the presence of:
WITNESS:                            Bio-Reference Laboratories, Inc.


/s/Roger Tolins                           By /s/Howard Dubinett
- --------------------------                  -------------------
                                        Howard Dubinett, Executive
                                          Vice President
                                        Date: December 14, 1999

WITNESS:


/s/Paul Levitt                            /s/Rebecca Klafter
- --------------                            ------------------
                                          Rebecca Klafter
                                          Date: December 14, 1999

                                      14


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
This Schedule contains summary financial information extracted from (a) the
Balance Sheet and Statement of Operations filed as part of the Quarterly Report
on Form 10-Q and is qualified in its entirety by reference to such (b) Report on
Form 10-Q.
</LEGEND>

<S>                            <C>
<PERIOD-TYPE>                              Year
<FISCAL-YEAR-END>                    OCT-31-1999
<PERIOD-END>                         OCT-31-1999
<CASH>                                 2,128,274
<SECURITIES>                                   0
<RECEIVABLES>                         18,615,496
<ALLOWANCES>                          15,312,935
<INVENTORY>                              572,279
<CURRENT-ASSETS>                      21,720,373
<PP&E>                                 5,211,467
<DEPRECIATION>                         3,039,128
<TOTAL-ASSETS>                        32,317,998
<CURRENT-LIABILITIES>                 18,268,350
<BONDS>                               12,905,365
                          0
                               60,408
<COMMON>                                  77,008
<OTHER-SE>                            23,294,673
<TOTAL-LIABILITY-AND-EQUITY>          32,317,998
<SALES>                               53,856,414
<TOTAL-REVENUES>                      53,856,414
<CGS>                                 30,850,337
<TOTAL-COSTS>                         57,282,246
<OTHER-EXPENSES>                       1,185,316
<LOSS-PROVISION>                       6,855,221
<INTEREST-EXPENSE>                     1,465,765
<INCOME-PRETAX>                      (4,611,148)
<INCOME-TAX>                             367,300
<INCOME-CONTINUING>                  (4,978,448)
<DISCONTINUED>                                 0
<EXTRAORDINARY>                                0
<CHANGES>                                      0
<NET-INCOME>                         (4,978,448)
<EPS-BASIC>                              (.68)
<EPS-DILUTED>                              (.68)


</TABLE>


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