VITRO DIAGNOSTICS INC
8-K/A, EX-16, 2000-11-02
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                           Larry O'Donnell, CPA, P.C.
Telephone (303) 745-4545                                    2280 So. Xanadu Way
                                                                      Suite 370
                                                          Aurora, Colorado 80014


October 27, 2000



Office of the Chief Accountant
SECPS Letter File
Securities and Exchange Commission
Mail Stop 9-5
450 Fifth Street, N.W.
Washington, D.C. 20549



Vitro Diagnostics, Inc.



I would like to inform you that I have read the revised disclosures  provided by
Vitro Diagnostics, Inc. (Comm. File # 0-17378) in its filing of Form 8-K/A dated
October 9, 2000 and that there are no  disagreements  regarding  the  statements
made under Item 4 - Changes in Registrant's Certifying Accountant.

Sincerely,

/s/ Larry O'Donnell, CPA, P.C.
------------------------------
Larry O'Donnell, CPA, P.C.




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