MERIDIAN DIAGNOSTICS INC
SC 13G/A, 1999-02-10
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                               (Amendment No. 12)*


                           MERIDIAN DIAGNOSTICS, INC.
- --------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   589602 10 1
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

[ ]      Rule 13d-1(b)

[X]      Rule 13d-1(c)

[ ]      Rule 13d-1(d)

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


                        (Continued on following page(s))

                                Page 1 of 4 Pages


<PAGE>


 CUSIP NO. 589602 10 1                 13G                   Page 2 of 4 Pages
- --------------------------------------------------------------------------------
 1      NAME OF REPORTING PERSONS
        S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           WILLIAM J. MOTTO
           ###-##-####
- --------------------------------------------------------------------------------
 2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                (a)
           See Item 4                                                    (b) [X]

- --------------------------------------------------------------------------------
 3      SEC USE ONLY


- --------------------------------------------------------------------------------
 4      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States of America
- --------------------------------------------------------------------------------
                        5      SOLE VOTING POWER

       NUMBER OF                 3,857,624
        SHARES          --------------------------------------------------------
     BENEFICIALLY       6      SHARED VOTING POWER
       OWNED BY
         EACH                    809,539
       REPORTING        --------------------------------------------------------
      PERSON WITH       7      SOLE DISPOSITIVE POWER

                                 3,857,624
                        --------------------------------------------------------
                        8      SHARED DISPOSITIVE POWER

                                 809,539
- --------------------------------------------------------------------------------
 9      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           4,667,163
- --------------------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*



- --------------------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

             32.3%
- --------------------------------------------------------------------------------
12      TYPE OF REPORTING PERSON*

             IN
- --------------------------------------------------------------------------------

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>



                                                               Page 3 of 4 Pages

ITEM 1(a)      Name of Issuer:  Meridian Diagnostics, Inc.

        1(b)   Address of Issuer's Principal Executive Office:

               3471 River Hills Drive
               Cincinnati, Ohio  45244

        2(a)   Name of Persons Filing:  William J. Motto

        2(b)   Address of Principal Business Office:

               3471 River Hills Drive
               Cincinnati, Ohio  45244

        2(c)   Citizenship:  U.S.A.

        2(d)   Title of Class of Securities:   Common Stock, No Par Value

        2(e)   CUSIP No.:    589602 10 1

        3.     If this Statement is Filed Pursuant to Rules 13d-1(b) or
               13d-2(b), check whether the Person Filing is a:   N/A

        4.     Ownership:

               (a)    See Item 9 of cover page.
               (b)    See Item 11 of cover page.
               (c)    See Items 5-8 of cover page.

               This  Amendment No. 12 to Schedule 13G is filed solely by William
          J.  Motto.  The  original  Schedule  13G and all  amendments  prior to
          Amendment  No. 6 to  Schedule  13G were  filed by William J. Motto and
          Jerry L. Ruyan on the same  Schedule 13G. The shares in Items 5, 7 and
          9 include  options  that are  exercisable  within 60 days into  75,452
          shares and 51,646  shares held by Mr.  Motto as trustee of the William
          J. Motto Family Charitable  Remainder  Unitrust.  The number of shares
          shown in Items 6, 8, and 9 for Mr. Motto includes  809,539 shares held
          by his children as trustees of certain irrevocable trusts.

               William J. Motto and Jerry L. Ruyan are  parties to an  agreement
          ("Agreement") with the Company pursuant to which they must offer their
          shares for sale to the Company, and if it declines to purchase, to the
          other at a price  based on current  market  prices,  if either of them
          desires to sell  shares in excess of 1% of the  Company's  outstanding
          Common Stock in any three-month period. Mr. Motto does not affirm that



<PAGE>


          the  Agreement  operates to make  Messrs.  Motto and Ruyan a group for
          purposes of Section  13(d)(3) of the Securities  Exchange Act of 1934.
          The  Agreement  previously  was filed as an  Exhibit  to  Registration
          Statement No.  33-6052.  The First  Amendment to the Agreement,  which
          removed Richard H. Walter as a party to the Agreement,  previously was
          filed as an Exhibit to the Form 10-K of Meridian Diagnostics, Inc. for
          the fiscal year ended September 30, 1992.

        5.     Ownership of 5% or less of class:  N/A

        6.     Ownership of more than 5% on behalf of another person:  N/A

        7.     Identification   and   classification  of  the  subsidiary  which
               acquired  the  security  being  reported  by the  parent  holding
               company:  N/A

        8.     Identification and classification of members of the group:  N/A

        9.     Notice of dissolution of group:  N/A


        10.    Certification:       N/A

     By signing  below,  I certify that, to the best of my knowledge and belief,
the  securities  referred  to above were not  acquired  and are not held for the
purpose of or with the effect of  changing  or  influencing  the  control of the
issuer of the  securities  and were not acquired and are not held in  connection
with or as a participant in any transaction having that purpose or effect.

                                    SIGNATURE

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.


                                                        January 31, 1999
                                                   ---------------------------
                                                               Date

                                                      /s/William J. Motto
                                                   ---------------------------
                                                            Signature


                                                          William J. Motto
                                                   ---------------------------
                                                             Name/Title



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