THERMO INSTRUMENT SYSTEMS INC
10-K, 1999-03-23
MEASURING & CONTROLLING DEVICES, NEC
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                     SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, DC 20549
            ----------------------------------------------------

                                 FORM 10-K

(mark one)
[ X ] Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange
      Act of 1934 for the fiscal year ended January 2, 1999

[   ] Transition Report Pursuant to Section 13 or 15(d) of the
      Securities  Exchange Act of 1934

                       Commission file number 1-9786

                       THERMO INSTRUMENT SYSTEMS INC.
           (Exact name of Registrant as specified in its charter)

Delaware                                                         04-2925809
(State or other jurisdiction of         (I.R.S. Employer Identification No.)
incorporation or organization)

860 West Airport Freeway, Suite 301
Hurst, Texas                                                          76054
(Address of principal executive offices)                         (Zip Code)

     Registrant's telephone number, including area code: (781) 622-1000

        Securities registered pursuant to Section 12(b) of the Act:

      Title of each class             Name of each exchange on which registered
  ------------------------------      -----------------------------------------
   Common Stock, $.10 par value               American Stock Exchange
  4% Convertible Subordinated
    Debentures due 2005                       American StockExchange

        Securities registered pursuant to Section 12(g) of the Act:
                                    None

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months, and (2) has been subject to the filing requirements for
at least the past 90 days. Yes [ X ] No [ ]

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of the Registrant's knowledge, in definitive proxy or information
statements incorporated by reference into Part III of this Form 10-K or any
amendment to this Form 10-K. [ ]

The aggregate market value of the voting stock held by nonaffiliates of the
Registrant as of January 29, 1999, was approximately $273,411,000.

As of January 29, 1999, the Registrant had 119,276,531 shares of Common Stock
outstanding.

                    DOCUMENTS INCORPORATED BY REFERENCE

Portions of the Registrant's Annual Report to Shareholders for the year ended
January 2, 1999, are incorporated by reference into Parts I and II.

Portions of the Registrant's definitive Proxy Statement for the Annual Meeting
of Shareholders to be held on May 27, 1999, are incorporated by reference into
Part III.

<PAGE>


                                   PART I
Item 1.   Business

(a) General Development of Business

    Thermo Instrument Systems Inc. (the Company or the Registrant) is a
worldwide leader in the development, manufacture, and marketing of measurement
instruments used to monitor, collect, and analyze information. These systems are
used for multiple applications in a range of industries, including industrial
processing, food and beverage production, life sciences research, and medical
diagnostics.

    The businesses of Thermo Instrument operate in four instrumentation
segments: Analytical, which includes the Company's 89%-owned ThermoQuest
Corporation and 93%-owned Thermo Optek Corporation subsidiaries; Life Sciences,
which includes 62%-owned Thermo BioAnalysis Corporation; Process Control, which
includes the Company's 80%-owned ONIX Systems Inc. and 67%-owned Metrika Systems
Corporation subsidiaries; and Industrial, which primarily includes the Company's
82%-owned ThermoSpectra Corporation, 78%-owned Thermo Vision Corporation, and
wholly owned subsidiaries.

    The Company adopted a strategy of spinning out certain of its businesses
into separate subsidiaries and having these subsidiaries sell a minority
interest to outside investors. The Company believes that this strategy provides
additional motivation and incentives for the management of the subsidiaries
through the establishment of subsidiary-level stock option incentive programs,
as well as capital to support the subsidiaries' growth. During 1998*, ONIX
Systems sold shares of its common stock in an initial public offering and Thermo
BioAnalysis sold shares of its common stock in a public offering for aggregate
net proceeds of $102.7 million. See Note 10 to Consolidated Financial Statements
in the Registrant's 1998 Annual Report to Shareholders for a description of the
issuance of stock by the Company's subsidiaries.

      The Company historically has expanded both through the acquisition of
companies and product lines and through internal development of new products and
technologies. During the past several years, the Company has completed a number
of complementary acquisitions that have provided additional technologies,
specialized manufacturing or product development expertise, and broader
capabilities in marketing and distribution. On February 22, 1999, the Company
declared unconditional in all respects its cash tender offer for all outstanding
shares of Spectra-Physics AB, a Stockholm Stock Exchange-listed company, for 160
Swedish krona per share (approximately $20 per share). As of that date, the
Company had acquired or received acceptances representing approximately 98% of
the Spectra-Physics shares outstanding. There are approximately 17.6 million
Spectra-Physics shares outstanding. The aggregate cost for Spectra-Physics will
total approximately $355 million. Payment was made for all shares as to which
acceptances had been received by March 1, 1999. Spectra-Physics manufactures a
wide range of laser-based instrumentation systems, primarily for the
process-control, industrial measurement, construction, research, commercial, and
government markets.

    The Company was incorporated in Delaware in May 1986 as a wholly owned
subsidiary of Thermo Electron Corporation to operate the instruments businesses
that were previously conducted by several Thermo Electron subsidiaries. As of
January 2, 1999, Thermo Electron owned 101,865,192 shares, or 85%, of the
Company's outstanding common stock. Thermo Electron is a world leader in
monitoring, analytical, and biomedical instrumentation; biomedical products
including heart-assist devices, respiratory-care equipment, and mammography
systems; and paper recycling and papermaking equipment. Thermo Electron also
develops alternative-energy systems and clean fuels, provides a range of
services including industrial outsourcing and environmental-liability
management, and conducts research and development in advanced imaging, laser,
and electronic information-management technologies.

- --------------------
* References to 1998, 1997, and 1996 herein are for the fiscal years ended
  January 2, 1999, January 3, 1998, and December 28, 1996, respectively.

                                       2
<PAGE>

    Thermo Electron intends for the foreseeable future to maintain at least 80%
ownership of the Company, so that it may continue to file consolidated U.S.
federal and certain state income tax returns with the Company. This may require
the purchase by Thermo Electron of additional shares of common stock and/or
convertible debentures of the Company from time to time as the number of
outstanding shares of the Company increases. These and any other purchases may
be made either in the open market or directly from the Company or pursuant to
conversions of the Company's 3 3/4% senior convertible note due 2000 held by
Thermo Electron. See Notes 4 and 6 to Consolidated Financial Statements in the
Registrant's 1998 Annual Report to Shareholders for a description of the
Company's outstanding stock options and convertible obligations. During 1998,
Thermo Electron purchased 2,046,300 shares of the Company's common stock in the
open market at a total cost of $53.2 million.

    During 1998, Thermo Electron announced a proposed reorganization involving
certain of Thermo Electron's subsidiaries, including the Company. As part of
this reorganization, ThermoSpectra may be taken private. The public shareholders
of ThermoSpectra would receive cash in exchange for their shares of common stock
of ThermoSpectra. The completion of these transactions is subject to numerous
conditions, as outlined in Note 17 to Consolidated Financial Statements in the
Registrant's 1998 Annual Report to Shareholders, which information is
incorporated herein by reference.

Forward-looking Statements

    Forward-looking statements, within the meaning of Section 21E of the
Securities Exchange Act of 1934, are made throughout this Annual Report on Form
10-K. For this purpose, any statements contained herein that are not statements
of historical fact may be deemed to be forward-looking statements. Without
limiting the foregoing, the words "believes," "anticipates," "plans," "expects,"
"seeks," "estimates," and similar expressions are intended to identify
forward-looking statements. There are a number of important factors that could
cause the results of the Company to differ materially from those indicated by
such forward-looking statements, including those detailed under the heading
"Forward-looking Statements" in the Registrant's 1998 Annual Report to
Shareholders, which statements are incorporated herein by reference.

(b) Financial Information About Segments

    Financial information concerning the Company's segments is summarized in
Note 13 to Consolidated Financial Statements in the Registrant's 1998 Annual
Report to Shareholders, which information is incorporated herein by reference.

(c) Description of Business

    (i) Principal Products and Services

Analytical

    ThermoQuest is a leading manufacturer of mass spectrometers, liquid
chromatographs, and gas chromatographs for the pharmaceutical, environmental,
and industrial marketplaces. These analytical instruments are used in the
quantitative and qualitative chemical analysis of organic and inorganic
compounds at ultratrace levels of detection. ThermoQuest also supplies
scientific equipment for the preparation and preservation of chemical samples,
and consumables for the chromatography industry.

    Thermo Optek is a worldwide leader in spectroscopy instrumentation for
molecular and elemental analysis based upon energy and light measurements, as
well as systems for materials sciences including surface analysis,
characterization, preparation, and physical-properties analysis.

                                       3
<PAGE>

Life Sciences

    Thermo BioAnalysis develops, manufactures, and markets instruments,
consumables, and information-management systems used in pharmaceutical research
and production, and in clinical diagnostics, including point-of-care test kits
for rapid diagnosis of certain illnesses.

Process Control

    ONIX Systems, which became a public subsidiary of the Company in March 1998,
designs, develops, markets, and services sophisticated field-measurement
instruments and on-line sensors for process-control industries, particularly the
oil and gas industry. These systems provide real-time data collection, analysis,
and local functions to enhance production efficiency, improve process and
quality control, ensure regulatory compliance, and increase employee safety.

    Metrika Systems manufactures on-line process optimization systems that
provide real-time, nondestructive analysis of the composition of raw materials
in basic-materials production processes, including coal, cement, and minerals.
In addition, Metrika Systems manufactures advanced systems used principally by
producers of finished flat metals, such as sheet metal, and web materials, such
as rubber, plastic foils, and glass, to measure and control parameters such as
thickness and coating weight of these materials.

Industrial

    ThermoSpectra develops, manufactures, and markets precision imaging and
inspection, temperature-control, and test and measurement instruments. These
instruments are generally combined with proprietary operations and analysis
software to provide industrial and research customers with integrated systems
that address their specific needs.

    Thermo Vision designs, manufactures, and markets a diverse array of
photonics products (light-based technologies) including optical components,
imaging sensors and systems, lasers, optically based instruments,
opto-electronics, and fiber optics, that are used in a wide range of
applications, including medical diagnostics and analytical instrumentation;
semiconductor manufacturing; X-ray imaging; physics, chemistry, and biology
research; and telecommunications.

    Thermo Instrument has wholly owned businesses, which produce instruments and
complete systems for detecting and monitoring environmental pollutants generated
from industrial and mobile sources and provides clinical laboratory equipment
and consumables that assist in the diagnosis of various diseases. In addition, a
wholly owned business of the Company has a joint venture with Thermo
BioAnalysis. This company, Thermo Nucleonics LLC, was established to address the
nuclear instrumentation market.

    (ii) and (xi) New Products; Research and Development

    The Company maintains active programs for the development of new
technologies and the enhancement of existing products. Research and development
expenses for the Company were $113.9 million, $107.6 million, and $84.1 million
in 1998, 1997, and 1996, respectively

    (iii)  Raw Materials

    Raw materials, components, and supplies purchased by the Company are
generally either available from a number of different suppliers or from
alternative sources that could be developed without a material adverse effect on
the Company. To date, the Company has experienced no difficulties in obtaining
these materials.

                                       4
<PAGE>

    (iv)   Patents, Licenses, and Trademarks

    The Company's policy is to protect its intellectual property rights,
including applying for and obtaining patents when appropriate. The Company holds
numerous patents related to its technologies, with additional patents pending.
The Company also enters into licensing agreements with other companies in which
it grants or receives rights to specific patents and technical know-how. The
Company also considers technical know-how, trade secrets, and trademarks to be
important to its business.

    (v)    Seasonal Influences

    There are no significant seasonal influences on the Company's sales of its
products.

    (vi)   Working Capital Requirements

    There are no special inventory requirements or credit terms extended to
customers that would have a material adverse effect on the Company's working
capital.

    (vii)  Dependency on a Single Customer

     No single customer accounted for more than 10% of the Company's total
revenues in any of the past three years.

    (viii) Backlog
<TABLE>
<CAPTION>
<S>                                                                                   <C>        <C>

      The Company's backlog of firm orders at year-end 1998 and 1997 was:

(In thousands)                                                                             1998       1997
- ------------------------------------------------------------------------------------- ---------- ----------

Analytical                                                                             $142,607   $151,532
Life Sciences                                                                            32,183     24,973
Process Control                                                                          55,345     53,435
Industrial                                                                               53,366     68,948
                                                                                      ---------   --------
                                                                                       $283,501   $298,888
                                                                                      =========   ========
</TABLE>
    Certain of these orders are cancelable by the customer upon payment of a
cancellation charge. The Company anticipates that substantially all of the
backlog as of January 2, 1999, will be shipped or completed during 1999. The
Company does not believe that the level of, or changes in the level of, its
backlog is necessarily indicative of intermediate or long-term trends in its
business. The decreases in backlog in the Analytical and Industrial segments
were principally due to a slowdown in the semiconductor and related industries
and a decrease in demand in Asia.

    (ix)   Government Contracts

    Not applicable.

    (x)    Competition

    The Company generally competes on the basis of technical advances that
result in new products and improved price/performance ratios, reputation among
customers as a quality leader for products and services, and active research and
application-development programs. To a lesser extent, the Company competes on
the basis of price.

                                       5
<PAGE>


    In many markets, the Company competes with large analytical instrument
companies such as Hewlett-Packard Co.; Perkin-Elmer Corporation; Varian
Associates, Inc.; and Hitachi, Ltd. Certain products manufactured by the Company
also compete with products sold by numerous smaller, specialized firms.

Analytical

    ThermoQuest competes in each of its markets primarily on technical
performance, customer service and support, and price. ThermoQuest's principal
competitors include the Chemical Analysis Group of Hewlett-Packard; the
MicroMass Group of Waters Corporation; Shimadzu Corporation; Perkin-Elmer;
Varian; Merck Corporation; Phenomenex Inc.; and
numerous regional suppliers.

    Thermo Optek competes in each of its markets primarily on performance,
reliability, customer service, and price. Thermo Optek competes primarily with
the Analytical Instruments division of Perkin-Elmer; Varian; Hewlett-Packard;
SpectroAnalytical Instruments, Inc.; Shimadzu; and Physical Electronics, Inc.

Life Sciences

    Thermo BioAnalysis competes primarily on the basis of technological
innovation, performance, flexibility, function, customization, and price. Major
competitors include Perkin-Elmer, Hewlett-Packard, and Waters.

Process Control

    The Company competes in the field measurement instruments and sensors market
primarily on quality and reliability, technical features, accuracy, ease of use,
price, and reputation for after-market service. ONIX Systems competes with a few
large competitors, including Fisher-Rosemount, a division of Emerson Electric
Co., Inc.; Asea Brown Boveri (Holding) Ltd. (ABB); Elsag-Bailey Process
Automation N.V., a division of ABB; and Yokogawa Electric Corporation, in each
of its product areas and with many companies within specific industries.

    Metrika Systems competes primarily on the basis of performance and, to a
lesser extent, price in the on-line coal, cement, and mineral analysis markets.
Scantech Limited is the Company's primary competitor in the on-line coal and
cement analysis market. Amdel of Australia is the Company's principal competitor
in the on-line minerals analysis market. The market for solids and multiphase
analyzers for process control is generally fragmented. Competition in the
thickness-gauging business is highly fragmented with numerous competitors
competing in various end-use market segments. As a result, competition varies
according to the end-use segment. Metrika Systems competes primarily on the
basis of quality, performance, and price.

    The Company has a relatively small presence within the large and varied
process-control marketplace, which is extremely fragmented and is comprised of
several large companies, including Fisher-Rosemount, Elsag Bailey, and Honeywell
Process Control, as well as numerous smaller companies. The Company competes in
this market primarily on the basis of technical performance, customer service,
price, and reliability.

Industrial

    Thermo Vision competes primarily on the basis of technical
suitability, product performance, reliability, and price.  Its principal
competitors include Optical Coating Laboratory, Inc. and Newport
Corporation.

    ThermoSpectra competes in each of its markets primarily on the basis of
technical advances that result in new products and improved price/performance
ratios and reputation among customers as a quality leader for products and
services. To a lesser extent, ThermoSpectra competes on the basis of price.
ThermoSpectra's principal competitors include Tektronix, Inc.; Brinkmann
Instruments Inc.; Julabo USA Inc.; Hamamatsu Photonics KK; and Oxford
Instruments plc.



                                       6
<PAGE>

    The Company is a leading manufacturer of ambient air-monitoring instruments
and a major manufacturer of source monitoring and worker-safety monitoring
instruments. The Company competes in these markets on the basis of technical
performance and reliability, as well as customer service. The Company's
principal competitors include Monitor Labs Incorporated, Advanced Pollution
Instruments, and Mine Safety Appliances Co.

    (xii)  Environmental Protection Regulations

    The Company believes that compliance by the Company with federal, state, and
local environmental protection regulations will not have a material adverse
effect on its capital expenditures, earnings, or competitive position.

    (xiii) Number of Employees

    As of January 2, 1999, the Company employed approximately 9,700 people.

(d) Financial Information About Geographic Areas

    Financial information about geographic areas is summarized in Note 13 to
Consolidated Financial Statements in the Registrant's 1998 Annual Report to
Shareholders and is incorporated herein by reference.

(e) Executive Officers of the Registrant

     Name                         Age  Present Title (Fiscal Year First
                                       Became Executive Officer)
     -----------------------------------------------------------------

     Earl R. Lewis                55  President and Chief Executive Officer
                                       (1990)
     Denis A. Helm                60  Executive Vice President (1986)
     Dr. Richard W. K. Chapman    54  Vice President (1994)
     Barry S. Howe                43  Vice President (1994)
     Theo Melas-Kyriazi           39  Chief Financial Officer (1998)
     Paul F. Kelleher             56  Chief Accounting Officer (1986)

    Each executive officer serves until his successor is chosen or appointed by
the Board of Directors and qualified or until earlier resignation, death, or
removal. All executive officers, except Mr. Lewis, Dr. Chapman, and Mr.
Melas-Kyriazi, have held comparable positions for at least five years, either
with the Company or with its parent company, Thermo Electron. Mr. Lewis was
named President of the Company in March 1997 and Chief Executive Officer in
January 1998. Mr. Lewis served as Chief Operating Officer of the Company from
January 1996 through January 1998, as Executive Vice President from January 1996
through March 1997, as a Senior Vice President from January 1994 through January
1996, and as a Vice President from March 1992 through January 1994. Dr. Chapman
has been President and Chief Executive Officer of ThermoQuest since its
inception in June 1995, and served as President of Finnigan Corporation, a
subsidiary of ThermoQuest, from 1992 to 1995. Mr. Melas-Kyriazi was appointed
Chief Financial Officer of the Company and Thermo Electron on January 1, 1999.
He joined Thermo Electron in 1986 as Assistant Treasurer, and became Treasurer
in 1988. He was named President and Chief Executive Officer of ThermoSpectra in
1994, a position he held until becoming Vice President of Corporate Strategy for
Thermo Electron in 1998. Mr. Melas-Kyriazi remains a Vice President of Thermo
Electron. Messrs. Lewis, Helm, Chapman, and Howe are full-time employees of the
Company. Messrs. Melas-Kyriazi and Kelleher are full-time employees of Thermo
Electron and certain of its subsidiaries, but devote such time to the affairs of
the Company as the Company's needs reasonably require.


                                       7
<PAGE>

Item 2. Properties

    The Company believes that its facilities are in good condition and are
suitable and adequate for its present operations and that suitable space is
readily available in the event any lease is not extended. With respect to leases
expiring in the near future, in the event the Company does not renew such
leases, the Company believes suitable alternate space is available for lease on
acceptable terms. The location of the Company's principal properties by segment
as of January 2, 1999, are:

Analytical

    The Company owns approximately 1,553,000 square feet of office, engineering,
laboratory, and production space, principally in Ohio, Wisconsin, Germany,
Massachusetts, Italy, England, and California, and leases approximately 997,000
square feet of office, engineering, laboratory, and production space under
leases expiring from 1999 through 2017, principally in the United Kingdom,
Massachusetts, New York, and California. As of January 2, 1999, the Company had
a $7.3 million mortgage loan that is secured by 200,000 square feet of property
in California with a net book value of $14.9 million.

Life Sciences

    The Company owns approximately 95,000 square feet of office, engineering,
laboratory, and production space in Pennsylvania and leases approximately
748,000 square feet of office, engineering, laboratory, and production space
under leases expiring from 1999 through 2016, principally in Finland, the United
Kingdom, and Texas.

Process Control

    The Company owns approximately 165,000 square feet of office, engineering,
laboratory, and production space in Texas, France, and England, and leases
approximately 638,000 square feet of office, engineering, laboratory, and
production space under leases expiring from 1999 through 2007, principally in
Texas, Maryland, and the United Kingdom.

Industrial

    The Company owns approximately 282,000 square feet of office, engineering,
laboratory, and production space, principally in Wisconsin, and leases
approximately 783,000 square feet of office, engineering, laboratory, and
production space under leases expiring from 1999 through 2008, principally in
California, New Hampshire, Massachusetts, Germany, and the Netherlands.

Item 3. Legal Proceedings

    Not applicable.

Item 4. Submission of Matters to a Vote of Security Holders

    Not applicable.

                                       8
<PAGE>


                                  PART II

Item 5.  Market for Registrant's Common Equity and Related Stockholder Matters

    Information concerning the market and market price for the Registrant's
common stock, $.10 par value, and dividend policy is included under the sections
labeled "Common Stock Market Information" and "Dividend Policy" in the
Registrant's 1998 Annual Report to Shareholders and is incorporated herein by
reference.

Item 6.  Selected Financial Data

    The information required under this item is included under the sections
labeled "Selected Financial Information" and "Dividend Policy" in the
Registrant's 1998 Annual Report to Shareholders and is incorporated herein by
reference.

Item 7. Management's Discussion and Analysis of Financial Condition and Results
         of Operations

    The information required under this item is included under the heading
"Management's Discussion and Analysis of Financial Condition and Results of
Operations" in the Registrant's 1998 Annual Report to Shareholders and
is incorporated herein by reference.

Item 7A. Quantitative and Qualitative Disclosures About Market Risk

    The information required under this item is included under the heading
"Management's Discussion and Analysis of Financial Condition and Results of
Operations" in the Registrant's 1998 Annual Report to Shareholders and
is incorporated herein by reference.

Item 8. Financial Statements and Supplementary Data

    The Registrant's Consolidated Financial Statements as of January 2, 1999,
and Supplementary Data are included in the Registrant's 1998 Annual Report to
Shareholders and are incorporated herein by reference.

Item 9. Changes in and Disagreements with Accountants on Accounting and
         Financial Disclosure

    Not applicable.

                                       9
<PAGE>

                                  PART III

Item 10. Directors and Executive Officers of the Registrant

    The information concerning directors required under this item is
incorporated herein by reference from the material contained under the caption
"Election of Directors" in the Registrant's definitive proxy statement to be
filed with the Securities and Exchange Commission pursuant to Regulation 14A,
not later than 120 days after the close of the fiscal year. The information
concerning delinquent filers pursuant to Item 405 of Regulation S-K is
incorporated herein by reference from the material contained under the heading
"Section 16(a) Beneficial Ownership Reporting Compliance" under the caption
"Stock Ownership" in the Registrant's definitive proxy statement to be filed
with the Securities and Exchange Commission pursuant to Regulation 14A, not
later than 120 days after the close of the fiscal year.

Item 11. Executive Compensation

    The information required under this item is incorporated herein by reference
from the material contained under the caption "Executive Compensation" in the
Registrant's definitive proxy statement to be filed with the Securities and
Exchange Commission pursuant to Regulation 14A, not later than 120 days after
the close of the fiscal year.

Item 12. Security Ownership of Certain Beneficial Owners and Management

    The information required under this item is incorporated herein by reference
from the material contained under the caption "Stock Ownership" in the
Registrant's definitive proxy statement to be filed with the Securities and
Exchange Commission pursuant to Regulation 14A, not later than 120 days after
the close of the fiscal year.

Item 13. Certain Relationships and Related Transactions

    The information required under this item is incorporated herein by reference
from the material contained under the caption "Relationship with Affiliates" in
the Registrant's definitive proxy statement to be filed with the Securities and
Exchange Commission pursuant to Regulation 14A, not later than 120 days after
the close of the fiscal year.


                                       10
<PAGE>

                                  PART IV

Item 14. Exhibits, Financial Statement Schedules, and Reports on Form 8-K

(a, d) Financial Statements and Schedules

    (1)The consolidated financial statements set forth in the list below are
       filed as part of this Report.

    (2)The consolidated financial statement schedule set forth in the list below
       is filed as part of this Report.

    (3)Exhibits filed herewith or incorporated herein by reference are set forth
       in Item 14(c) below.

    List of Financial Statements and Schedules Referenced in this Item 14

    Information incorporated by reference from Exhibit 13 filed herewith:

Consolidated Statement of Income
       Consolidated Statement of Income
       Consolidated Balance Sheet
       Consolidated Statement of Cash Flows
       Consolidated Statement of Comprehensive Income and Shareholders'
        Investment
       Notes to Consolidated Financial Statements
       Report of Independent Public Accountants

    Financial Statement Schedules filed herewith:

       Schedule II:  Valuation and Qualifying Accounts

    All other schedules are omitted because they are not applicable or not
    required, or because the required information is shown either in the
    financial statements or in the notes thereto.

(b) Reports on Form 8-K

    On December 10, 1998, the Company filed a Current Report on Form 8-K, with
    respect to a proposed reorganization by the Company's ultimate parent
    corporation, Thermo Electron Corporation, involving certain of Thermo
    Electron's subsidiaries, including the Company.

(c) Exhibits

    See Exhibit Index on the page immediately preceding exhibits.

                                       11
<PAGE>

                                 SIGNATURES
    Pursuant to the requirements of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized.

Date:  March 22, 1999               THERMO INSTRUMENT SYSTEMS INC.


                                    By: /s/ Earl R. Lewis
                                        Earl R. Lewis
                                        President and Chief Executive
Officer

    Pursuant to the requirements of the Securities Exchange Act of 1934, this
report has been signed below by the following persons on behalf of the
Registrant and in the capacities indicated, as of March 22, 1999.

Signature                           Title


By: /s/ Earl R. Lewis               President, Chief Executive Officer,
    Earl R. Lewis                     and Director


By: /s/ Theo Melas-Kyriazi          Chief Financial Officer
    Theo Melas-Kyriazi


By: /s/ Paul F. Kelleher            Chief Accounting Officer
    Paul F. Kelleher


By: /s/ Frank Borman                Director
    Frank Borman


By: /s/ George N. Hatsopoulos       Director
    George N. Hatsopoulos


By: /s/ John N. Hatsopoulos         Director
    John N. Hatsopoulos


By: /s/ Arvin H. Smith              Chairman of the Board and Director
        Arvin H. Smith


By: /s/ Polyvios C. Vintiadis       Director
    Polyvios C. Vintiadis

                                       12
<PAGE>

                  Report of Independent Public Accountants
To the Shareholders and Board of Directors of Thermo Instrument Systems
Inc.:

    We have audited, in accordance with generally accepted auditing standards,
the consolidated financial statements included in Thermo Instrument Systems
Inc.'s Annual Report to Shareholders incorporated by reference in this Form
10-K, and have issued our report thereon dated February 16, 1999 (except with
respect to the matter discussed in Note 18, as to which the date is March 1,
1999). Our audits were made for the purpose of forming an opinion on those
statements taken as a whole. The schedule listed in Item 14 on page 11 is the
responsibility of the Company's management and is presented for purposes of
complying with the Securities and Exchange Commission's rules and is not part of
the basic consolidated financial statements. This schedule has been subjected to
the auditing procedures applied in the audits of the basic consolidated
financial statements and, in our opinion, fairly states, in all material
respects, the financial data required to be set forth therein in relation to the
basic consolidated financial statements taken as a whole.



                                               Arthur Andersen LLP



Boston, Massachusetts
February 16, 1999

                                       13
<PAGE>
<TABLE>
<CAPTION>


SCHEDULE II

                                      THERMO INSTRUMENT SYSTEMS INC.
                                    Valuation and Qualifying Accounts
                                              (In thousands)

<S>                                 <C>         <C>         <C>         <C>         <C>         <C>

Description                                      Provision    Accounts    Accounts   Other (a)     Balance
                                    Balance at  Charged to   Recovered     Written        Off       at End
                                     Beginning     Expense                                         of Year
                                            of
                                          Year
- ----------------------------------- ----------- ----------- ----------- ----------- ----------- -----------

Allowance for Doubtful Accounts

Year Ended January 2, 1999             $22,786     $ 4,169    $    502     $(7,221)    $ 3,490    $ 23,726

Year Ended January 3, 1998             $16,981     $ 4,366    $    304     $(4,375)    $ 5,510    $ 22,786

Year Ended December 28, 1996           $12,569     $ 2,274    $     69     $(5,015)    $ 7,084    $ 16,981
</TABLE>
<TABLE>
<CAPTION>
<S>                                          <C>         <C>            <C>         <C>         <C>


 Description                                 Balance at    Established    Activity   Other (c)     Balance
                                              Beginning     as Cost of  Charged to                  at End
                                                  of      Acquisitions     Reserve                 of Year
                                                   Year
 ------------------------------------------- ----------- -------------- ----------- ----------- -----------

 Accrued Acquisition Expenses (b)

 Year Ended January 2, 1999                    $ 21,966      $   7,218    $ (9,517)  $  (3,164)   $ 16,503

 Year Ended January 3, 1998                    $ 20,563      $  24,752    $(18,665)  $  (4,684)   $ 21,966

 Year Ended December 28, 1996                  $ 14,838      $  38,782    $(26,571)  $  (6,486)   $ 20,563


   Description                                Balance at     Provision    Activity   Other (f)     Balance
                                               Beginning    Charged to  Charged to                  at End
                                                   of      Expense (e)     Reserve                 of Year
                                                    Year
 -------------------------------------------- ----------- ------------- ----------- ----------- -----------

 Accrued Restructuring Costs (d)

 Year Ended January 2, 1999                     $    244      $ 18,401     $(7,682)  $    263     $ 11,226

 Year Ended January 3, 1998                     $  1,024      $    953     $(1,733)  $      -     $    244

 Year Ended December 28, 1996                   $    308      $  1,038     $  (322)  $      -     $  1,024

(a) Includes allowance of businesses acquired during the year as described in
    Note 3 to Consolidated Financial Statements in the Company's 1998 Annual
    Report to Shareholders and the effect of foreign currency translation.
(b) The nature of activity in this account is described in Note 3 to
    Consolidated Financial Statements in the Registrant's 1998 Annual Report to
    Shareholders.
(c) Represents reversal of accrued acquisition expenses and corresponding
    reduction of cost in excess of net assets of acquired companies resulting
    from finalization of restructuring plans and the effect of foreign currency
    translation.
(d) The nature of activity in this account is described in Note 11 to
    Consolidated Financial Statements in the Registrant's 1998 Annual Report to
    Shareholders.
(e) Excludes provision of $2.8 million for asset write-downs and $0.4 million
    for loss on division sold in 1998.
(f) Represents the effect of foreign currency translation.

</TABLE>


                                       14
<PAGE>
<TABLE>
<CAPTION>
<S>        <C>

                               EXHIBIT INDEX
Exhibit
Number     Description of Exhibit

  2.1      Reserved.

  2.2      Agreement and Release dated as of December 15, 1997, among Fisons
           plc, the Registrant, and Thermo Electron (filed as Exhibit 2.2 to the
           Registrant's Annual Report on Form 10-K for the fiscal year ended
           January 3, 1998 [File No. 1-9876] and incorporated herein by
           reference).

  3.1      Amendment to Restated Certificate of Incorporation of the Registrant
           (filed as Exhibit 3.1 to the Registrant's Quarterly Report on Form
           10-Q for the quarter ended June 29, 1996 [File No. 1-9786] and
           incorporated herein by reference).

  3.2      By-Laws of the Registrant (filed as Exhibit 3(b) to the Registrant's
           Annual Report on Form 10-K for the fiscal year ended January 2, 1993
           [File No. 1-9786] and incorporated herein by reference).

  4.1      Subordinated Indenture, dated January 15, 1998, among the
           Registrant, Thermo Electron, and Bankers Trust Company as
           trustee, relating to $250,000,000 principal amount of 4%
           Convertible Subordinated Debentures due 2005 (filed as Exhibit
           4.1 to the Registrant's Current Report on Form 8-K filed with
           the Commission on January 16, 1998, and incorporated herein by
           reference).

  4.2      Senior convertible note purchase agreement by and between the
           Registrant and Thermo Electron as of September 15, 1993 (filed as
           Exhibit 10(a) to the Registrant's Quarterly Report on Form 10-Q for
           the quarter ended October 2, 1993 [File No. 1-9786] and incorporated
           by reference).

           The Registrant hereby agrees, pursuant to Item 601(b) (4) (iii) (A)
           of Regulation S-K, to furnish to the Commission upon request, a copy
           of each instrument with respect to other long-term debt of the
           Registrant or its subsidiaries.

 10.1      Amended and Restated Corporate Services Agreement, dated as of
           January 3, 1993, between Thermo Electron and the Registrant (filed as
           Exhibit 10(a) to the Registrant's Annual Report on Form 10-K for the
           fiscal year ended January 2, 1993 [File No. 1-9786] and incorporated
           herein by reference).

 10.2      Tax Allocation Agreement dated as of May 29, 1986, between Thermo
           Electron and the Registrant (filed as Exhibit 10(b) to the
           Registrant's Registration Statement on Form S-1 [Reg. No. 33-6762]
           and incorporated herein by reference).

 10.3      Thermo Electron Corporate Charter, as amended and restated effective
           January 3, 1993 (filed as Exhibit 10(f) to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 2, 1993 [File
           No. 1-9786] and incorporated herein by reference).

 10.4      Form of Indemnification Agreement with Directors and Officers (filed as
           Exhibit 10(g) to the Registrant's Annual Report on Form 10-K for the
           fiscal year ended December 29, 1990 [File No. 1-9786] and
           incorporated herein by reference).

 10.5      Plan for sale of shares by the Registrant to Thermo Electron (filed
           as Exhibit 10(dd) to the Registrant's Quarterly Report on Form 10-Q
           for the quarter ended July 3, 1993 [File No. 1-9786] and incorporated
           herein by reference).

 10.6      Master Repurchase Agreement dated December 28, 1996, between the
           Registrant and Thermo Electron (filed as Exhibit 10.6 to the
           Registrant's Annual Report on Form 10-K for the fiscal year ended
           December 28, 1996 [File No. 1-9786] and incorporated
           herein by reference).

                                       15
<PAGE>

Exhibit
Number     Description of Exhibit

 10.7      Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated December 2, 1997, by and among the Registrant and
           Thermo Electron (filed as Exhibit 10.7 to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 3, 1998 [File
           No. 1-9786] and incorporated herein by reference).

 10.8      Restated Stock Holdings Assistance Plan and Form of Promissory Note
           (filed as Exhibit 10.10 to the Registrant's Annual Report on Form
           10-K for the fiscal year ended January 3, 1998 [File No. 1-9786] and
           incorporated herein by reference).

 10.9-10.15     Reserved.

 10.16     Deferred Compensation Plan for Directors of the Registrant
           (filed as Exhibit 10(f) to the Registrant's Registration
           Statement on Form S-1 [Reg. No. 33-6762] and incorporated
           herein by reference).

 10.17     Directors' Stock Option Plan of the Registrant (filed as Exhibit
           10.17 to the Registrant's Annual Report on Form 10-K for the fiscal
           year ended December 31, 1994 [File No. 1-9786] and incorporated
           herein by reference).

 10.18     Incentive Stock Option Plan of the Registrant (filed as Exhibit
           10(c) to the Registrant's Registration Statement on Form S-1
           [Reg. No. 33-6762] and incorporated herein by reference).
           (Maximum number of shares issuable in the aggregate under this
           plan and the Registrant's Nonqualified Stock Option Plan is
           3,515,625 shares, after adjustment to reflect share increase
           approved in 1990; 3-for-2 stock splits effected in January
           1988, July 1993, and April 1995; and 5-for-4 stock splits
           effected in December 1995 and October 1997).

 10.19     Nonqualified Stock Option Plan of the Registrant (filed as
           Exhibit 10(d) to the Registrant's Registration Statement on
           Form S-1 [Reg. No. 33-6762] and incorporated herein by
           reference).  (Maximum number of shares issuable in the
           aggregate under this plan and the Registrant's Incentive Stock
           Option Plan is 3,515,625 shares, after adjustment to reflect
           share increase approved in 1990; 3-for-2 stock splits effected
           in January 1988, July 1993, and April 1995; and 5-for-4 stock
           splits effected in December 1995 and October 1997).

 10.20     Equity Incentive Plan of the Registrant (filed as Appendix A to
           the Proxy Statement dated April 27, 1993, of the Registrant
           [File No. 1-9786] and incorporated herein by reference).
           (Maximum number of shares issuable is 5,039,062 shares, after
           adjustment to reflect share increase approved in December 1993;
           3-for-2 stock splits effected in July 1993 and April 1995; and
           5-for-4 stock splits effected in December 1995 and October
           1997).

 10.21     Finnigan Corporation 1979 Long-term Incentive Stock Option Plan
           (filed as Exhibit 10.21 to the Registrant's Annual Report on Form
           10-K for the fiscal year ended December 31, 1994 [File No. 1-9786]
           and incorporated herein by reference).

 10.22     Former Thermo Environmental Corporation Incentive Stock Option
           Plan (filed as Exhibit 10(d) to Thermo Environmental's
           Registration Statement on Form S-1 [Reg. No. 33-329] and
           incorporated herein by reference).  (Maximum number of shares
           issuable in the aggregate under this plan and the Former Thermo
           Environmental Corporation Nonqualified Stock Option Plan is
           1,450,195 shares, after adjustment to reflect share increase
           approved in 1987; 3-for-2 stock splits effected in July 1993
           and April 1995; and 5-for-4 stock splits effected in December
           1995 and October 1997).

                                       16
<PAGE>

Exhibit
Number     Description of Exhibit

 10.23     Former Thermo Environmental Corporation Nonqualified Stock
           Option Plan (filed as Exhibit 10(e) to Thermo Environmental's
           Registration Statement on Form S-1 [Reg. No. 33-329] and
           incorporated herein by reference).  (Maximum number of shares
           issuable in the aggregate under this plan and the Former Thermo
           Environmental Corporation Incentive Stock Option Plan is
           1,450,195 shares, after adjustment to reflect share increase
           approved in 1987; 3-for-2 stock splits effected in July 1993
           and April 1995; and 5-for-4 stock splits effected in December
           1995 and October 1997).

 10.24     Thermo Instrument Systems Inc. - ThermoSpectra Corporation
           Nonqualified Stock Option Plan (filed as Exhibit 10.51 to the
           Registrant's Annual Report on Form 10-K for the fiscal year
           ended December 31, 1994 [File No. 1-9786] and incorporated
           herein by reference).

 10.25     Thermo Instrument Systems Inc. - ThermoQuest Corporation Nonqualified
           Stock Option Plan (filed as Exhibit 10.65 to Thermo Cardiosystems'
           Annual Report on Form 10-K for the fiscal year ended December 30,
           1995 [File No. 1-10114] and incorporated herein by reference).

 10.26     Thermo Instrument Systems Inc. - Thermo BioAnalysis Corporation
           Nonqualified Stock Option Plan (filed as Exhibit 10.64 to Thermo
           Cardiosystems' Annual Report on Form 10-K for the fiscal year ended
           December 30, 1995 [File No. 1-10114] and incorporated herein by
           reference).

 10.27     Thermo Instrument Systems Inc. - Thermo Optek Corporation
           Nonqualified Stock Option Plan (filed as Exhibit 10.27 to the
           Registrant's Annual Report on Form 10-K for the fiscal year
           ended December 28, 1996 [File No. 1-9786] and incorporated
           herein by reference).

 10.28     Thermo Instrument Systems Inc. - Metrika Systems Corporation
           Nonqualified Stock Option Plan (filed as Exhibit 10.28 to the
           Registrant's Annual Report on Form 10-K for the fiscal year ended
           January 3, 1998 [File No. 1-9786] and incorporated herein by
           reference).

 10.29     Thermo Instrument Systems Inc. - Thermo Vision Corporation
           Nonqualified Stock Option Plan (filed as Exhibit 10.29 to the
           Registrant's Annual Report on Form 10-K for the fiscal year ended
           January 3, 1998 [File No. 1-9786] and incorporated herein by
           reference).

 10.30     Thermo Instrument Systems Inc. - ONIX Systems Inc. Nonqualified Stock
           Option Plan (filed as Exhibit 10.30 to the Registrant's Annual Report
           on Form 10-K for the fiscal year ended January 3, 1998 [File No.
           1-9786] and incorporated herein by reference).

           In addition to the stock-based compensation plans of the Registrant,
           the executive officers of the Registrant may be granted awards under
           stock-based compensation plans of Thermo Electron for services
           rendered to the Registrant. The terms of such plans are substantially
           the same as those of the Registrant's Equity Incentive Plan.

 10.31 - 10.32  Reserved.

 10.33     3 3/4% Senior Convertible Note in the principal amount of
           $140,000,000 dated September 15, 1993, issued to Thermo Electron
           (filed as Exhibit 10(b) to the Registrant's Quarterly Report on Form
           10-Q for the quarter ended October 2, 1993 [File No. 1-9786] and
           incorporated herein by reference).

                                       17
<PAGE>

Exhibit
Number     Description of Exhibit

 10.34     $45,000,000 Promissory Note dated as of September 12, 1997,
           issued by ThermoSpectra to Thermo Electron (filed as Exhibit 10
           to ThermoSpectra's Quarterly Report on Form 10-Q for the
           quarter ended September 27, 1997 [File No. 1-13876] and
           incorporated herein by reference).

 10.35     Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated as of December 5, 1997, between Thermo Optek and
           Thermo Electron (filed as Exhibit 10.35 to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 3, 1998 [File
           No. 1-9786] and incorporated herein by reference).

 10.36     Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated as of December 3, 1997, between ThermoQuest and
           Thermo Electron (filed as Exhibit 10.36 to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 3, 1998 [File
           No. 1-9786] and incorporated herein by reference).

 10.37     Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated as of December 3, 1997, between Metrika Systems and
           Thermo Electron (filed as Exhibit 10.37 to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 3, 1998 [File
           No. 1-9786] and incorporated herein by reference).

 10.38     Master Guarantee Reimbursement and Loan Agreement dated as of
           November 14, 1997, between Thermo Vision and Thermo Electron (filed
           as Exhibit 10.38 to the Registrant's Annual Report on Form 10-K for
           the fiscal year ended January 3, 1998 [File No. 1-9786] and
           incorporated herein by reference).

 10.39     Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated as of December 2, 1997, between Thermo BioAnalysis
           and Thermo Electron (filed as Exhibit 10.39 to the Registrant's
           Annual Report on Form 10-K for the fiscal year ended January 3, 1998
           [File No. 1-9786] and incorporated herein by reference).

 10.40     Amended and Restated Master Guarantee Reimbursement and Loan
           Agreement dated as of December 4, 1997, between ThermoSpectra and
           Thermo Electron (filed as Exhibit 10.40 to the Registrant's Annual
           Report on Form 10-K for the fiscal year ended January 3, 1998 [File
           No. 1-9786] and incorporated herein by reference).

 10.41     Amended and Restated Master Guarantee Reimbursement and Loan Agreement dated
           as of January 5, 1998, between ONIX Systems and Thermo Electron
           (filed as Exhibit 10.5 to the Registration Statement of ONIX Systems
           on Form S-1 [Reg. No. 333-45333] and incorporated herein by
           reference).

 10.42     Fiscal Agency Agreement dated as of August 3, 1995, among ThermoQuest,
           Thermo Electron, and The Chase Manhattan Bank (formerly Chemical
           Bank) (filed as Exhibit 10.12 to ThermoQuest's Registration Statement
           on Form S-1 [Reg. No. 333-00276] and incorporated herein by
           reference).

 10.43     Fiscal Agency Agreement dated as of October 12, 1995, between Thermo Optek,
           Thermo Electron, and The Chase Manhattan Bank (formerly Chemical
           Bank) (filed as Exhibit 10.10 to Thermo Optek's Registration
           Statement on Form S-1 [Reg. No. 333-03630] and incorporated herein by
           reference).

 10.44     $200,000,000 Promissory Note dated as of March 3, 1999, issued by the
           Registrant to Thermo Electron.

                                       18
<PAGE>

Exhibit
Number     Description of Exhibit

 13        Annual Report to Shareholders for the year ended January 2, 1999
           (only those portions incorporated herein by reference).

 21        Subsidiaries of the Registrant.

 23        Consent of Arthur Andersen LLP.

 27        Financial Data Schedule.

</TABLE>


     THE  SECURITIES  REPRESENTED  HEREBY  HAVE NOT BEEN  REGISTERED  UNDER  THE
SECURITIES  ACT OF 1933,  AS AMENDED (THE  "ACT").  THESE  SECURITIES  HAVE BEEN
ACQUIRED FOR INVESTMENT,  AND NOT WITH A VIEW TO DISTRIBUTION OR RESALE, AND MAY
NOT BE SOLD,  PLEDGED,  MORTGAGED,  HYPOTHECATED  OR OTHERWISE  TRANSFERRED  (1)
WITHOUT  AN  EFFECTIVE  REGISTRATION  STATEMENT  UNDER  THE ACT  COVERING  THESE
SECURITIES OR (2) UNLESS AN EXEMPTION FROM REGISTRATION IS AVAILABLE.


                         THERMO INSTRUMENT SYSTEMS INC.
                       Promissory Note Due August 27, 1999
                                  Hurst, Texas


                                                                   March 3, 1999

     For value received,  Thermo Instrument Systems Inc., a Delaware corporation
(the  "Company"),   hereby  promises  to  pay  to  Thermo  Electron  Corporation
(hereinafter  referred to as the "Payee"),  or its assigns,  on or before August
27, 1999, the principal sum of two hundred  million  dollars  ($200,000,000)  or
such part thereof as then remains  unpaid.  The Company  shall pay interest from
the date hereof  through April 3, 1999 on the principal  amount  remaining  from
time to time  unpaid at a rate per  annum  equal to  5.03%.  Thereafter,  if the
Company's total U.S. consolidated cash invested with the Payee equals or exceeds
the aggregate  outstanding  principal amount of this Note, the Company shall pay
interest on the principal  amount  remaining  from time to time unpaid at a rate
per annum equal to the Dealer  Commercial  Paper Rate for 30-day  maturities  as
reported in the Wall  Street  Journal on the first  business  day of each fiscal
month of the Company (the "DCP Rate"), plus twenty-five (25) basis points, which
rate shall be adjusted on the second  business  day of each fiscal  month of the
Company  and shall be in effect  for the  entirety  of such  fiscal  month.  If,
however,  the Company's total U.S.  consolidated cash invested with the Payee is
less than the  aggregate  outstanding  principal  amount of this  Note,  (A) the
Company  shall pay  interest  at a rate per annum equal to the DCP Rate plus one
hundred twenty-five (125) basis points on that portion (the "Excess Portion") of
the unpaid  principal  amount equal to (i) the aggregate  outstanding  principal
amount, minus (ii) the Company's total U.S.  consolidated cash invested with the
Payee,  and (B) the Company  shall pay interest at a rate per annum equal to the
DCP Rate plus  twenty-five  (25)  basis  points on that  portion  of the  unpaid
principal amount equal to (i) the aggregate  outstanding principal amount, minus
(ii) the  Excess  Portion.  Each of the  interest  rates  set forth in the prior
sentence  shall be adjusted on the second  business  day of each fiscal month of
the  Company  and shall be in effect  for the  entirety  of such  fiscal  month.
Interest  is payable in  arrears  on the third day of each  fiscal  month of the
Company,  until all amounts  outstanding are paid in full. Overdue principal and
interest  shall bear  interest at a rate per annum equal to the rate of interest
announced  from time to time by  BankBoston  Corporation  at its head  office in
Boston,  Massachusetts  as its "base rate" plus one percent (1%).  Principal and
all accrued  but unpaid  interest  shall be due and payable on August 27,  1999.
Principal and interest  shall be payable in lawful money of the United States of
America, in immediately available funds, at the principal office of the Payee or
at such  other  place as the legal  holder  may  designate  from time to time in
writing to the Company. Interest shall be computed on an actual 360-day basis.

      This Note may be prepaid at any time or from time to time,  in whole or in
part, without any premium or penalty.  All prepayments shall be applied first to
accrued interest and then to principal. The then unpaid principal amount of, and
interest outstanding on, this Note shall be

<PAGE>


                                      2
and become  immediately due and payable without notice or demand,  at the option
of the holder hereof, upon the occurrence of any of the following events:

            (a) the  failure of the  Company  to pay any  amount  due  hereunder
      within ten (10) days of the date when due;

            (b) any  representation,  warranty or statement made or furnished to
      the Payee by the Company in connection  with this Note or the  transaction
      from which it arises shall prove to have been false or  misleading  in any
      material respect as of the date when made or furnished;

            (c) the  failure of the Company to pay its debts as they become due,
      the insolvency of the Company, the filing by or against the Company of any
      petition  under the U.S.  Bankruptcy  Code (or the  filing of any  similar
      petition under the insolvency law of any  jurisdiction),  or the making by
      the  Company  of an  assignment  or  trust  mortgage  for the  benefit  of
      creditors or the  appointment  of a receiver,  custodian or similar  agent
      with  respect to, or the taking by any such person of  possession  of, any
      property of the Company;

            (d)   the sale by the Company of all or substantially all of its
     assets;

            (e) the  merger or  consolidation  of the  Company  with or into any
      other  corporation  in a  transaction  in  which  the  Company  is not the
      surviving entity;

            (f) the issuance of any writ of  attachment,  by trustee  process or
      otherwise, or any restraining order or injunction not removed, repealed or
      dismissed  within  thirty (30) days of issuance,  against or affecting the
      person or property of the Company or any  liability or  obligation  of the
      Company to the holder hereof; and

            (g) the  suspension of the  transaction of the usual business of the
     Company.

      Upon  surrender of this Note for  transfer or exchange,  a new Note or new
Notes of the same tenor  dated the date to which  interest  has been paid on the
surrendered  Note and in an  aggregate  principal  amount  equal  to the  unpaid
principal amount of the Note so surrendered will be issued to, and registered in
the name of, the transferee or transferees.  The Company may treat the person in
whose  name this Note is  registered  as the owner  hereof  for the  purpose  of
receiving payment and for all other purposes.

      In case any payment  herein  provided  for shall not be paid when due, the
Company further promises to pay all cost of collection, including all reasonable
attorneys' fees.

      No delay or  omission  on the part of the  Payee in  exercising  any right
hereunder  shall  operate as a waiver of such right or of any other right of the
Payee,  nor shall any delay,  omission or waiver on any one occasion be deemed a
bar to or waiver  of the same or any other  right on any  future  occasion.  The
Company hereby waives presentment, demand, notice of prepayment, protest and all
other  demands  and  notices  in  connection  with  the  delivery,   acceptance,
performance, default or enforcement of this Note. The undersigned hereby assents
to any  indulgence  and any  extension  of time for payment of any  indebtedness
evidenced hereby granted or permitted by the Payee.

      This Note shall be governed by and construed in accordance  with, the laws
of the  Commonwealth  of  Massachusetts  and shall  have the  effect of a sealed
instrument.

<PAGE>

                                    THERMO INSTRUMENT SYSTEMS INC.


                                    By: /s/Earl R. Lewis
                                        -----------------------------------
                                        Earl R. Lewis
                                        President and CEO

[Corporate Seal]

Attest:


/s/Sandra Lambert
- ------------------------------
Sandra L. Lambert
Secretary



                                                                     Exhibit 13
















                         Thermo Instrument Systems Inc.

                        Consolidated Financial Statements

                                      1998


<PAGE>
<TABLE>
<CAPTION>


Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                        Consolidated Statement of Income
<S>                                                                     <C>         <C>         <C>       
                                       
(In thousands except per share amounts)                                       1998        1997        1996
- ----------------------------------------------------------------------- ----------- ----------- -----------

Revenues                                                                $1,659,981  $1,592,314  $1,209,362
                                                                        ----------  ----------  ----------

Costs and Operating Expenses:
  Cost of revenues (Note 11)                                               889,575     842,009     654,165
  Selling, general, and administrative expenses (Note 8)                   447,860     424,695     340,963
  Research and development expenses                                        113,917     107,613      84,091
  Restructuring and nonrecurring (income) expense, net (Notes 3 and 11)     23,209      (1,257)      3,500
                                                                        ----------  ----------  ----------

                                                                         1,474,561   1,373,060   1,082,719
                                                                        ----------  ----------  ----------

Operating Income                                                           185,420     219,254     126,643

Interest Income                                                             33,509      28,253      20,490
Interest Expense (includes $11,136, $18,014, and $8,145 to                 (45,458)    (45,894)    (28,923)
  parent company)
Gain on Issuance of Stock by Subsidiaries (Note 10)                         18,582      46,404      71,713
Other Income                                                                 1,863           -           -
                                                                        ----------  ----------  ----------

Income Before Provision for Income Taxes, Minority Interest, and           193,916     248,017     189,923
  Extraordinary Item
Provision for Income Taxes (Note 5)                                         74,674      88,113      51,727
Minority Interest Expense                                                   15,677      12,646       5,445
                                                                        ----------  ----------  ----------

Income Before Extraordinary Item                                           103,565     147,258     132,751
Extraordinary Item, Net of Provision for Income Taxes and                      519           -           -
  Minority Interest of $391 (Note 6)
                                                                        ----------  ----------  ----------

Net Income                                                              $  104,084  $  147,258  $  132,751
                                                                        ==========  ==========  ==========

Earnings per Share (Note 15)
  Basic                                                                 $      .86  $     1.21  $     1.12
                                                                        ==========  ==========  ==========

  Diluted                                                               $      .79  $     1.09  $     1.01
                                                                        ==========  ==========  ==========

Weighted Average Shares (Note 15)
  Basic                                                                    120,975     121,548     118,857
                                                                        ==========  ==========  ==========

  Diluted                                                                  133,103     139,415     135,351
                                                                        ==========  ==========  ==========







The accompanying notes are an integral part of these consolidated financial
statements.


                                       2
<PAGE>

Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                           Consolidated Balance Sheet
(In thousands)                                                                            1998        1997
- ----------------------------------------------------------------------------------- ----------- ------------

Assets
Current Assets:
  Cash and cash equivalents (includes $408,490 and $283,995 under                   $  553,825  $  468,848
    repurchase agreements with parent company)
  Available-for-sale investments, at quoted market value (amortized cost of                  -       8,328
    $8,287 in 1997; Note 2)
  Accounts receivable, less allowances of $23,726 and $22,786                          407,430     364,075
  Unbilled contract costs and fees                                                      13,114       9,191
  Inventories                                                                          276,589     264,719
  Prepaid expenses                                                                      19,705      19,292
  Prepaid and refundable income taxes (Note 5)                                          62,921      54,915
                                                                                    ----------  ----------

                                                                                     1,333,584   1,189,368
                                                                                    ----------  ----------

Property, Plant, and Equipment, at Cost, Net                                           220,231     219,939
                                                                                    ----------  ----------

Other Assets (Notes 2 and 4)                                                            73,705      45,477
                                                                                    ----------  ----------

Cost in Excess of Net Assets of Acquired Companies (Notes 3 and 5)                     938,254     896,369
                                                                                    ----------  ----------

                                                                                    $2,565,774  $2,351,153
                                                                                    ==========  ==========


                                       3
<PAGE>

Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                     Consolidated Balance Sheet (continued)
(In thousands except share amounts)                                                       1998        1997
- ----------------------------------------------------------------------------------- ----------- -----------

Liabilities and Shareholders' Investment
Current Liabilities:
  Notes payable and current maturities of long-term obligations (includes           $  130,772  $  116,226
    $60,000 and $55,000 due to parent company; Notes 3 and 6)
  Accounts payable                                                                     101,009      97,516
  Accrued payroll and employee benefits                                                 59,649      59,745
  Accrued income taxes (includes $12,500 and $20,000 due to parent company)             59,984      61,409
  Accrued installation and warranty expenses                                            39,958      42,404
  Deferred revenue                                                                      46,354      41,759
  Other accrued expenses                                                               135,708     135,616
  Due to parent company and affiliated companies (Note 3)                               14,195      22,027
                                                                                    ----------  ----------

                                                                                       587,629     576,702
                                                                                    ----------  ----------

Deferred Income Taxes (Note 5)                                                          29,278      30,430
                                                                                    ----------  ----------

Other Deferred Items                                                                    31,056      27,273
                                                                                    ----------  ----------

Long-term Obligations (Note 6):
  Senior convertible obligations (includes $140,000 due to parent company)             327,042     327,824
  Subordinated convertible obligations                                                 389,436     160,547
  Other (includes $3,800 and $168,800 due to parent company; Note 3)                    26,965     184,823
                                                                                    ----------  ----------

                                                                                       743,443     673,194
                                                                                    ----------  ----------

Minority Interest                                                                      229,361     165,996
                                                                                    ----------  ----------

Commitments and Contingencies (Note 7)

Shareholders' Investment (Notes 4 and 9):
  Common stock, $.10 par value, 250,000,000 shares authorized; 122,879,889              12,288      12,265
    and 122,645,040 shares issued
  Capital in excess of par value                                                       331,621     333,580
  Retained earnings                                                                    675,983     571,899
  Treasury stock at cost, 3,603,358 and 670,827 shares                                 (63,671)     (6,965)
  Accumulated other comprehensive items (Note 14)                                      (11,214)    (33,221)
                                                                                    ----------  ----------

                                                                                       945,007     877,558
                                                                                    ----------  ----------
                                                                                    $2,565,774  $2,351,153
                                                                                    ==========  ==========




The accompanying notes are an integral part of these consolidated financial
statements.


                                       4
<PAGE>

Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                      Consolidated Statement of Cash Flows
(In thousands)                                                                 1998        1997        1996
- ------------------------------------------------------------------------- ---------- ----------- ----------

Operating Activities
  Net income                                                              $ 104,084  $  147,258  $ 132,751
  Adjustments to reconcile net income to net cash provided by
    operating activities:
      Depreciation and amortization                                          61,429      54,993     44,233
      Provision for losses on accounts receivable                             4,169       4,366      2,274
      Noncash restructuring and nonrecurring (income) expense,                3,226      (1,257)     3,500
        net (Notes 3 and 11)
      Gain on issuance of stock by subsidiaries (Note 10)                   (18,582)    (46,404)   (71,713)
      Gain on sale of investments (Note 2)                                     (713)          -          -
      Minority interest expense                                              15,677      12,646      5,445
      Increase (decrease) in deferred income taxes                              (53)      2,742       (757)
      Extraordinary item, net of income taxes and minority interest            (519)          -          -
        (Note 6)
      Other noncash expenses                                                 14,730       6,158      4,889
      Change in current accounts, excluding the effects of
       acquisitions:
        Accounts receivable                                                  (1,404)    (19,157)     1,394
        Inventories                                                          10,110      13,768     14,184
        Other current assets                                                    963       3,547      3,978
        Accounts payable                                                     (5,310)     14,317     (9,903)
        Other current liabilities                                           (14,763)    (23,868)   (24,686)
      Other                                                                  (1,638)        205        290
                                                                          ---------  ----------  ---------

         Net cash provided by operating activities                          171,406     169,314    105,879
                                                                          ---------  ----------  ---------

Investing Activities
  Acquisitions, net of cash acquired (Note 3)                              (129,598)   (508,059)  (248,150)
  Payment to affiliated company for acquired business (Note 3)              (19,117)          -          -
  Refund of acquisition purchase price (Note 3)                                   -      36,132          -
  Proceeds from sale of businesses (Note 11)                                      -       4,980          -
  Purchase of available-for-sale investments                                 (6,919)     (9,000)   (10,250)
  Proceeds from sale and maturities of available-for-sale                     9,005      10,250      3,000
     investments
  Purchases of property, plant, and equipment                               (30,902)    (29,198)   (19,134)
  Proceeds from sale of property, plant, and equipment                        9,510       7,877      4,597
  Other, net                                                                    730       2,030        530
                                                                          ---------  ----------  ---------

         Net cash used in investing activities                            $(167,291) $ (484,988) $(269,407)
                                                                          ---------  ----------  ---------


                                       5
<PAGE>

Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                Consolidated Statement of Cash Flows (continued)
(In thousands)                                                                 1998        1997        1996
- ------------------------------------------------------------------------- ---------- ----------- -----------

Financing Activities
  Net proceeds from issuance of Company and subsidiary common             $ 103,327  $   91,375  $  127,024
    stock (Note 10)
  Net proceeds from issuance of subordinated convertible                    244,111           -           -
    debentures (Note 6)
  Net proceeds from issuance of long-term obligations                        11,502           -     168,850
  Proceeds from issuance of short- and long-term obligations to                   -     428,800     110,000
    parent company (Notes 3 and 6)
  Repurchase of Company and subsidiary common stock, and                   (119,792)          -           -
    subordinated convertible debentures (Note 6)
  Repayment of short- and long-term obligations to parent company          (160,000)   (220,000)    (95,000)
    (Note 6)
  Increase (decrease) in short-term obligations, net                            500     (21,528)    (12,770)
  Repayment of long-term obligations                                         (2,780)     (7,817)     (5,133)
                                                                          ---------  ----------  ----------

         Net cash provided by financing activities                           76,868     270,830     292,971
                                                                          ---------  ----------  ----------

Exchange Rate Effect on Cash                                                  3,994      (8,996)     (1,988)
                                                                          ---------  ----------  ----------

Increase (Decrease) in Cash and Cash Equivalents                             84,977     (53,840)    127,455
Cash and Cash Equivalents at Beginning of Year                              468,848     522,688     395,233
                                                                          ---------  ----------  ----------

Cash and Cash Equivalents at End of Year                                  $ 553,825  $  468,848  $  522,688
                                                                          =========  ==========  ==========

Cash Paid For
  Interest                                                                $  44,899  $   43,755  $   25,837
  Income taxes                                                            $  66,423  $   62,895  $   42,636

Noncash Activities
  Fair value of assets of acquired companies                              $ 165,220  $  673,382  $  487,218
  Cash paid for acquired companies                                         (132,933)   (545,303)   (258,785)
  Due to affiliated company for acquired company                                  -     (19,117)          -
  Issuance of subsidiary stock options for acquired company                       -      (1,693)          -
                                                                          ---------  ----------  ----------

    Liabilities assumed of acquired companies                             $  32,287  $  107,269  $  228,433
                                                                          =========  ==========  ==========

  Conversions of Company and subsidiary convertible obligations           $   7,562  $   38,910  $   67,594
                                                                          =========  ==========  ==========








The accompanying notes are an integral part of these consolidated financial
statements.
</TABLE>

                                       6
<PAGE>
<TABLE>
<CAPTION>
<S>                                                                         <C>        <C>        <C>      


Thermo Instrument Systems Inc.                                                  1998 Financial Statements

               Consolidated Statement of Comprehensive Income and Shareholders' Investment
(In thousands)                                                                   1998      1997        1996
- --------------------------------------------------------------------------- ---------- ---------- ---------

Comprehensive Income
Net Income                                                                  $ 104,084  $147,258   $ 132,751
                                                                            ---------  --------   ---------

Other Comprehensive Items (Note 14):
  Foreign currency translation adjustment                                      22,917   (34,317)     (1,754)
  Unrealized gains (losses) on available-for-sale investments, net               (910)       22          14
                                                                            ---------  --------   ---------
    of reclassification adjustment

                                                                               22,007   (34,295)     (1,740)
                                                                            ---------  --------   ---------

  Minority Interest                                                            (4,248)    4,162        (339)
                                                                            ---------  --------   ---------

                                                                            $ 121,843  $117,125   $ 130,672
                                                                            =========  ========   =========

Shareholders' Investment
Common Stock, $.10 Par Value:
  Balance at beginning of year                                              $  12,265  $  9,767   $   9,257
  Issuance of stock under employees' and directors' stock plans                    17         4           5
  Conversions of convertible obligations                                            6        45         505
  Effect of stock split                                                             -     2,449           -
                                                                            ---------  --------   ---------

  Balance at end of year                                                       12,288    12,265       9,767
                                                                            ---------  --------   ---------

Capital in Excess of Par Value:
  Balance at beginning of year                                                333,580   319,464     248,468
  Issuance of stock under employees' and directors' stock plans                   590     1,270         950
  Tax benefit related to employees' and directors' stock plans                    158       514         199
  Conversions of convertible obligations                                          765     6,817      65,924
  Effect of stock split                                                             -    (2,449)          -
  Effect of majority-owned subsidiaries' equity transactions                   (3,472)    7,964       3,923
                                                                            ---------  --------   ---------

  Balance at end of year                                                      331,621   333,580     319,464
                                                                            ---------  --------   ---------

Retained Earnings:
  Balance at beginning of year                                                571,899   424,641     291,890
  Net income                                                                  104,084   147,258     132,751
                                                                            ---------  --------   ---------

  Balance at end of year                                                    $ 675,983  $571,899   $ 424,641
                                                                            ---------  --------   ---------


                                       7
<PAGE>

Thermo Instrument Systems Inc.                                                  1998 Financial Statements

         Consolidated Statement of Comprehensive Income and Shareholders' Investment (continued)
(In thousands)                                                                   1998      1997        1996
- --------------------------------------------------------------------------- ---------- ---------- ---------

Treasury Stock:
  Balance at beginning of year                                              $  (6,965) $ (8,679)  $  (9,724)
  Activity under employees' and directors' stock plans                            102     1,714       1,045
  Purchases of Company common stock                                           (56,808)        -           -
                                                                            ---------  --------   ---------

  Balance at end of year                                                      (63,671)   (6,965)     (8,679)
                                                                            ---------  --------   ---------

Accumulated Other Comprehensive Items (Note 14):
  Balance at beginning of year                                                (33,221)    1,074       2,814
  Other comprehensive (income) expense                                         22,007   (34,295)     (1,740)
                                                                            ---------  --------   ---------

  Balance at end of year                                                      (11,214)  (33,221)      1,074
                                                                            ---------  --------   ---------

                                                                            $ 945,007  $877,558   $ 746,267
                                                                            =========  ========   =========


















The accompanying notes are an integral part of these consolidated financial
statements.


                                       8
<PAGE>


Thermo Instrument Systems Inc.                                                  1998 Financial Statements

                   Notes to Consolidated Financial Statements
1.    Nature of Operations and Summary of Significant Accounting Policies

Nature of Operations
      Thermo Instrument Systems Inc. (the Company) is a worldwide leader in the
development, manufacture, and marketing of measurement instruments used to
monitor, collect, and analyze information. These systems are used for multiple
applications in a range of industries, including industrial processing, food and
beverage production, life sciences research, and medical diagnostics.

Relationship With Thermo Electron Corporation
      The Company was incorporated on May 28, 1986, as a wholly owned subsidiary
of Thermo Electron Corporation. As of January 2, 1999, Thermo Electron owned
101,865,192 shares of the Company's common stock, representing 85% of such stock
outstanding.
      During 1998, Thermo Electron announced a proposed reorganization involving
certain of Thermo Electron's subsidiaries, including the Company and
ThermoSpectra Corporation, a publicly traded subsidiary of the Company. As part
of this reorganization, Thermo Electron announced that ThermoSpectra may be
taken private (Note 17).

Principles of Consolidation
      The accompanying financial statements include the accounts of the Company;
its wholly owned subsidiaries; and its majority-owned public subsidiaries,
ThermoSpectra, ThermoQuest Corporation, Thermo Optek Corporation, Thermo
BioAnalysis Corporation, Metrika Systems Corporation, Thermo Vision Corporation,
and ONIX Systems Inc. All material intercompany accounts and transactions have
been eliminated. The Company accounts for investments in businesses in which it
owns between 20% and 50% using the equity method.

Fiscal Year
      The Company has adopted a fiscal year ending the Saturday nearest December
31. References to 1998, 1997, and 1996 are for the fiscal years ended January 2,
1999, January 3, 1998, and December 28, 1996, respectively. Fiscal years 1998
and 1996 each included 52 weeks; fiscal 1997 included 53 weeks.

Revenue Recognition
      The Company generally recognizes product revenues upon shipment of its
products and recognizes service contract revenues ratably over the term of the
contract. The Company provides a reserve for its estimate of warranty and
installation costs at the time of shipment. Deferred revenue in the accompanying
balance sheet consists primarily of unearned revenue on service contracts.
Substantially all of the deferred revenue in the accompanying 1998 balance sheet
will be recognized within one year.

Gain on Issuance of Stock by Subsidiaries
      At the time a subsidiary sells its stock to unrelated parties at a price
in excess of its book value, the Company's net investment in that subsidiary
increases. If at that time the subsidiary is an operating entity, and not
engaged principally in research and development, the Company records the
increase as a gain.
      If gains have been recognized on issuances of a subsidiary's stock and
shares of the subsidiary are subsequently repurchased by the subsidiary, the
Company, or Thermo Electron, gain recognition does not occur on issuances
subsequent to the date of a repurchase until such time as shares have been
issued in an amount equivalent to the number of repurchased shares. Such
transactions are reflected as equity transactions, and the net effect of these
transactions is reflected in the accompanying statement of comprehensive income
and shareholders' investment as "Effect of majority-owned subsidiaries' equity
transactions."

                                       9
<PAGE>

1.    Nature of Operations and Summary of Significant Accounting Policies (continued)

Stock-based Compensation Plans
      The Company applies Accounting Principles Board Opinion (APB) No. 25,
"Accounting for Stock Issued to Employees" and related interpretations in
accounting for its stock-based compensation plans (Note 4). Accordingly, no
accounting recognition is given to stock options granted at fair market value
until they are exercised. Upon exercise, net proceeds, including tax benefits
realized, are credited to shareholders' investment.

Income Taxes
      The Company and Thermo Electron have a tax allocation agreement under
which the Company and its greater than 80%-owned subsidiaries, exclusive of
foreign operations, are included in Thermo Electron's consolidated federal and
certain state income tax returns. The agreement provides that in years in which
the Company has taxable income, it will pay to Thermo Electron amounts
comparable to the taxes the Company would have paid if it had filed separate tax
returns. If Thermo Electron's equity ownership of the Company were to drop below
80%, the Company would be required to file its own federal income tax return.
      In accordance with Statement of Financial Accounting Standards (SFAS) No.
109, "Accounting for Income Taxes," the Company recognizes deferred income taxes
based on the expected future tax consequences of differences between the
financial statement basis and the tax basis of assets and liabilities,
calculated using enacted tax rates in effect for the year in which the
differences are expected to be reflected in the tax return.

Earnings per Share
      Basic earnings per share have been computed by dividing net income by the
weighted average number of shares outstanding during the year. Diluted earnings
per share have been computed assuming the conversion of convertible obligations
and the elimination of the related interest expense, and the exercise of stock
options, as well as their related income tax effects.

Stock Split
      All share and per share information has been restated to reflect a
five-for-four stock split, effected in the form of a 25% stock dividend, which
was distributed in October 1997.

Cash and Cash Equivalents
      At year-end 1998 and 1997, $392.0 million and $284.0 million,
respectively, of the Company's cash equivalents were invested in a repurchase
agreement with Thermo Electron. Under this agreement, the Company in effect
lends excess cash to Thermo Electron, which Thermo Electron collateralizes with
investments principally consisting of corporate notes, U.S. government-agency
securities, commercial paper, money market funds, and other marketable
securities, in the amount of at least 103% of such obligation. The Company's
funds subject to the repurchase agreement are readily convertible into cash by
the Company. The repurchase agreement earns a rate based on the 90-day
Commercial Paper Composite Rate plus 25 basis points, set at the beginning of
each quarter.
      At year-end 1998, $16.5 million of the Company's cash equivalents,
denominated in Dutch guilders, were invested in a repurchase agreement with a
wholly owned subsidiary of Thermo Electron. Under this agreement, the Company in
effect lends excess cash to the subsidiary, which Thermo Electron collateralizes
with investments principally consisting of corporate notes, U.S.
government-agency securities, commercial paper, money market funds, and other
marketable securities, in the amount of at least 103% of such obligation. The
Company's funds subject to the repurchase agreement are readily convertible into
cash by the Company. The repurchase agreement earns a rate based on Netherlands
market rates, set at the beginning of each month.
      The Company, along with other subsidiaries of Thermo Electron,
participates in a notional pool arrangement with Barclays Bank, which includes a
$71 million credit facility. The Company has access to $45 million under this
credit facility. Only U.K.-based subsidiaries of Thermo Electron participate in
this arrangement. Under this

                                       10
<PAGE>

1.    Nature of Operations and Summary of Significant Accounting Policies (continued)

arrangement, Barclays notionally combines the positive and negative cash
balances held by the participants to calculate the net interest yield/expense
for the group. The benefit derived from this arrangement is then allocated based
on balances attributable to the respective participants. Thermo Electron
guarantees all of the obligations of each participant in this arrangement. At
year-end 1998 and 1997, the Company had a positive cash balance under this
arrangement of $26.7 million and a negative cash balance of $1.5 million,
respectively.
      At year-end 1998 and 1997, the Company's cash equivalents also include
investments in short-term certificates of deposit of the Company's foreign
subsidiaries, which have an original maturity of three months or less. Cash
equivalents are carried at cost, which approximates market value.

Inventories
      Inventories are stated at the lower of cost (on a first-in, first-out or
weighted average basis) or market value and include materials, labor, and
manufacturing overhead. The components of inventories are:

(In thousands)                                                                              1998       1997
- -------------------------------------------------------------------------------------- ---------- ----------

Raw Materials and Supplies                                                             $ 118,286  $ 118,611
Work in Progress                                                                          55,086     52,870
Finished Goods                                                                           103,217     93,238
                                                                                       ---------  ---------

                                                                                       $ 276,589  $ 264,719
                                                                                       =========  =========

Property, Plant, and Equipment
      The costs of additions and improvements are capitalized, while maintenance
and repairs are charged to expense as incurred. The Company provides for
depreciation and amortization using the straight-line method over the estimated
useful lives of the property as follows: buildings and improvements, 5 to 40
years; machinery and equipment, 1 to 12 years; and leasehold improvements, the
shorter of the term of the lease or the life of the asset. Property, plant, and
equipment consists of:

(In thousands)                                                                              1998       1997
- -------------------------------------------------------------------------------------- ---------- ----------

Land                                                                                   $  33,335  $  33,539
Buildings                                                                                124,875    123,533
Machinery and Equipment                                                                  171,307    148,930
Leasehold Improvements                                                                    14,851     11,603
                                                                                       ---------  ---------

                                                                                         344,368    317,605
Less:  Accumulated Depreciation and Amortization                                         124,137     97,666
                                                                                       ---------  ---------

                                                                                       $ 220,231  $ 219,939
                                                                                       =========  =========

Other Assets
      Other assets in the accompanying balance sheet includes the costs of
acquired trademarks, patents, and other specifically identifiable intangible
assets. These assets are amortized using the straight-line method over their
estimated useful lives, which range from 3 to 20 years. These assets were $32.3
million and $16.2 million, net of accumulated amortization of $22.9 million and
$19.3 million, at year-end 1998 and 1997, respectively. Other assets in the
accompanying balance sheet also includes prepaid pension costs (Note 4),
deferred debt expense, and, in 1998, long-term available-for-sale investments
(Note 2).


                                       11
<PAGE>

1.    Nature of Operations and Summary of Significant Accounting Policies (continued)

Cost in Excess of Net Assets of Acquired Companies
      The excess of cost over the fair value of net assets of acquired companies
is amortized using the straight-line method over periods not exceeding 40 years.
Accumulated amortization was $104.5 million and $78.0 million at year-end 1998
and 1997, respectively. The Company assesses the future useful life of this
asset whenever events or changes in circumstances indicate that the current
useful life has diminished. The Company considers the future undiscounted cash
flows of the acquired companies in assessing the recoverability of this asset.
If impairment has occurred, any excess of carrying value over fair value is
recorded as a loss.

Environmental Liabilities
      The Company accrues for costs associated with the remediation of
environmental pollution when it is probable that a liability has been incurred
and the Company's proportionate share of the amount can be reasonably estimated.
Any recorded liabilities have not been discounted.

Foreign Currency
      All assets and liabilities of the Company's foreign subsidiaries are
translated at year-end exchange rates, and revenues and expenses are translated
at average exchange rates for the year in accordance with SFAS No. 52, "Foreign
Currency Translation." Resulting translation adjustments, net of minority
interest, are reflected in the "Accumulated other comprehensive items" component
of shareholders' investment (Note 14). In 1998, the Company recorded a foreign
currency transaction gain of $1.2 million, arising from the repayment of a
foreign subsidiary's intercompany borrowings denominated in U.S. dollars, which
is included in other income in the accompanying statement of income. Foreign
currency transaction gains and losses are included in the accompanying statement
of income and are not material for 1997 and 1996.

Forward Contracts
      The Company uses short-term forward foreign exchange contracts to manage
certain exposures to foreign currencies. The Company enters into forward foreign
exchange contracts to hedge certain firm purchase and sale commitments
denominated in currencies other than its subsidiaries' local currencies. These
contracts principally hedge transactions denominated in U.S. dollars, British
pounds sterling, Japanese yen, French francs, and German marks. The purpose of
the Company's foreign currency hedging activities is to protect the Company's
local currency cash flows related to these commitments from fluctuations in
foreign exchange rates. Gains and losses arising from forward foreign exchange
contracts are recognized as offsets to gains and losses resulting from the
transactions being hedged. The Company does not enter into speculative foreign
currency agreements.

Use of Estimates
      The preparation of financial statements in conformity with generally
accepted accounting principles requires management to make estimates and
assumptions that affect the reported amounts of assets and liabilities,
disclosure of contingent assets and liabilities at the date of the financial
statements, and the reported amounts of revenues and expenses during the
reporting period. Actual results could differ from those estimates.

Presentation
      Certain amounts in 1997 and 1996 have been reclassified to conform to the
presentation in the 1998 financial statements.
</TABLE>


                                       12
<PAGE>

2.    Available-for-sale Investments

      The Company's debt and marketable equity securities are considered
available-for-sale investments in the accompanying balance sheet and are carried
at market value, with the difference between cost and market value, net of
related tax effects and minority interest, recorded in the "Accumulated other
comprehensive items" component of shareholders' investment. The aggregate market
value, cost basis, and gross unrealized gains of short- and long-term
available-for-sale investments by major security type are:
<TABLE>
<CAPTION>
<S>                                                                      <C>         <C>         <C>     

(In thousands)                                                                                        Gross
                                                                             Market        Cost  Unrealized
                                                                              Value       Basis       Gains
                                                                                                   (Losses)
- ------------------------------------------------------------------------ ----------- ----------- -----------

1998
Equity Securities                                                           $ 5,574     $ 6,919     $(1,345)
                                                                            =======     =======     =======

1997
Corporate Bonds                                                             $ 6,105     $ 6,091     $    14
Equity Securities                                                             2,083       2,056          27
Other                                                                           140         140           -
                                                                            -------     -------     -------

                                                                            $ 8,328     $ 8,287     $    41
                                                                            =======     =======     =======

      Long-term available-for-sale investments are included in other assets in
the accompanying 1998 balance sheet. The cost of available-for-sale investments
that were sold was based on specific identification in determining realized
gains recorded in the accompanying statement of income. Other income in the
accompanying 1998 statement of income includes a gain of $0.7 million from the
sale of an available-for-sale investment.

3.    Acquisitions

      During 1998, the Company acquired several businesses for $129.6 million in
cash, net of cash acquired.
      In March 1997, the Company acquired 95% of Life Sciences International
PLC, a London Stock Exchange-listed company. Subsequently, the Company acquired
the remaining shares of Life Sciences' capital stock. The aggregate purchase
price for Life Sciences was approximately $442.8 million, net of $55.8 million
of cash acquired. The purchase price includes the repayment of $105.0 million of
Life Sciences' bank debt. Life Sciences manufactures laboratory science
equipment, appliances, instruments, consumables, and reagents for the research,
clinical, and industrial markets. In March 1997, to partially finance the
acquisition of Life Sciences, the Company borrowed $210.0 million from Thermo
Electron pursuant to a promissory note due March 1999 (Note 6). The Company
repaid $105.0 million of this promissory note in September 1997 and the
remaining $105.0 million in January 1998 (Note 6).
      On November 6, 1997, Thermo Power Corporation, a majority-owned subsidiary
of Thermo Electron, acquired Peek plc. Thereafter, ONIX Systems acquired from
Thermo Power the stock of three businesses comprising the Peek Measurement
Business for $19.1 million. The purchase price was determined based on the net
book value of the Peek Measurement Business at November 6, 1997, a pro rata
allocation of Thermo Power's total cost in excess of net assets of acquired
companies recorded in connection with its acquisition of Peek plc based on the
1997 revenues of the Peek Measurement Business relative to Peek plc's total
revenues, plus an estimate of Thermo Power's tax liability that arose from the
sale of the business to ONIX Systems. The Peek Measurement Business manufactures
flow and density measurement systems for use in the water/wastewater and oil and
gas industries. The purchase price is included in due to parent company and
affiliated companies in the accompanying 1997 balance sheet and was paid in
1998.

                                       13
<PAGE>


3.    Acquisitions (continued)

      During 1997, the Company made several other acquisitions for approximately
$46.2 million, net of cash acquired and including the repayment of $1.3 million
of bank debt, and the issuance of subsidiary stock options valued at an
aggregate $1.7 million. To partially finance 1997 acquisitions, ThermoSpectra
borrowed an aggregate of $60.0 million from Thermo Electron pursuant to
promissory notes due 1999 and Thermo Vision borrowed $3.8 million from Thermo
Electron pursuant to a promissory note due 2000 (Note 6).
      In March 1996, the Company completed the acquisition of a substantial
portion of the businesses constituting the Scientific Instruments Division of
Fisons plc (the Fisons businesses), a wholly owned subsidiary of Rhone-Poulenc
Rorer Inc. (RPR), for approximately $181.2 million, net of $7.7 million of cash
acquired, and the assumption of approximately $47.2 million of indebtedness. In
December 1997, the Company and RPR negotiated a post-closing adjustment under
the terms of the purchase agreement for the acquisition of the Fisons businesses
pertaining to determination of the net assets of the Fisons businesses at the
date of acquisition. This negotiation resulted in a refund to the Company of
$36.1 million, plus $3.8 million of interest from the date of acquisition. The
Company recorded $33.1 million of the refund as a reduction of cost in excess of
net assets of acquired companies. The remaining $3.0 million represented payment
for uncollected accounts receivable acquired by the Company that was guaranteed
by RPR. In 1996, the Company wrote off $3.5 million of acquired technology
relating to this acquisition, which represents the portion of the purchase price
allocated to technology in development based on estimated replacement cost. The
Fisons businesses are involved in the research, development, manufacture, and
sale of analytical instruments to industrial and research laboratories
worldwide.
      To finance the acquisition of the Fisons businesses, the Company used
available cash in addition to borrowings from Thermo Electron (Note 6). During
1996, the Company made several other acquisitions for an aggregate $67.0 million
in cash, net of cash acquired.
      These acquisitions have been accounted for using the purchase method of
accounting, and their results have been included in the accompanying financial
statements from their respective dates of acquisition. The aggregate cost of
these acquisitions exceeded the estimated fair value of the acquired net assets
by $609.4 million, which is being amortized over periods not exceeding 40 years.
Allocation of the purchase price for these acquisitions was based on estimates
of the fair value of the net assets acquired and, for acquisitions completed in
fiscal 1998, is subject to adjustment upon finalization of the purchase price
allocation. The Company has gathered no information that indicates the final
purchase price allocations will differ materially from the preliminary
estimates.
      Based on unaudited data, the following table presents selected financial
information for the Company, Life Sciences, and the Fisons businesses, on a pro
forma basis, assuming the Company, Life Sciences, and the Fisons businesses had
been combined since the beginning of 1996. The effect of the acquisitions not
included in the pro forma data was not material to the Company's results of
operations.

(In thousands except per share amounts)                                                    1997        1996
- -----------------------------------------------------------------------  ----------- ----------- -----------

Revenues                                                                             $1,645,086  $1,637,582
Net Income                                                                              126,528     119,842
Earnings per Share: 
  Basic                                                                                    1.04        1.01
  Diluted                                                                                   .95         .92

      The pro forma results are not necessarily indicative of future operations
or the actual results that would have occurred had the acquisition of Life
Sciences or the Fisons businesses been made at the beginning of 1996.
</TABLE>

                                       14
<PAGE>


3.    Acquisitions (continued)

      In connection with these acquisitions, the Company has undertaken
restructuring activities at the acquired businesses. The Company's restructuring
activities, which were accounted for in accordance with Emerging Issues Task
Force Pronouncement (EITF) 95-3, primarily have included reductions in staffing
levels and the abandonment of excess facilities. In connection with these
restructuring activities, as part of the cost of the acquisitions, the Company
established reserves as detailed below, primarily for severance and excess
facilities. In accordance with EITF 95-3, the Company finalizes its
restructuring plans no later than one year from the respective dates of the
acquisitions. A summary of the changes in accrued acquisition expenses, which
are included in other accrued expenses in the accompanying balance sheet, is:
<TABLE>
<CAPTION>
<S>                                             <C>            <C>            <C>            <C>     

                                                                 Abandonment
                                                                   of Excess
(In thousands)                                      Severance     Facilities          Other          Total
- ----------------------------------------------- -------------- -------------- -------------- --------------

Balance at December 30, 1995                         $  5,974       $  8,416       $    448       $ 14,838
  Reserves established                                 25,256          9,730          3,796         38,782
   Usage                                              (18,121)        (6,985)        (1,465)       (26,571)
  Decrease due to finalization of                      (1,872)        (3,560)        (1,243)        (6,675)
    restructuring plan, recorded as a
    decrease to cost in excess of net
    assets of acquired companies
  Currency translation adjustment                           -              -            189            189
                                                     --------       --------       --------       --------

Balance at December 28, 1996                           11,237          7,601          1,725         20,563
  Reserves established                                  9,493         11,804          3,455         24,752
   Usage                                              (12,137)        (5,153)        (1,375)       (18,665)
  Decrease due to finalization of                      (3,260)        (1,160)           (21)        (4,441)
    restructuring plan, recorded as a
    decrease to cost in excess of net
    assets of acquired companies
  Currency translation adjustment                           -              -           (243)          (243)
                                                     --------       --------       --------       --------

Balance at January 3, 1998                              5,333         13,092          3,541         21,966
  Reserves established                                  4,164          2,140            914          7,218
   Usage                                               (4,862)        (3,297)        (1,358)        (9,517)
  Decrease due to finalization of                        (829)          (253)        (2,389)        (3,471)
    restructuring plan, recorded as a
    decrease to cost in excess of net
    assets of acquired companies
  Currency translation adjustment                           -              -            307            307
                                                     --------       --------       --------       --------

Balance at January 2, 1999                           $  3,806       $ 11,682       $  1,015       $ 16,503
                                                     ========       ========       ========       ========

      Unresolved matters at January 2, 1999, primarily included completion of
planned severances and consolidation of excess facilities for certain
acquisitions completed during 1998.
</TABLE>

                                       15
<PAGE>

4.    Employee Benefit Plans

Stock-based Compensation Plans

Stock Option Plans
      The Company has stock-based compensation plans for its key employees,
directors, and others. These plans permit the grant of a variety of stock and
stock-based awards as determined by the human resources committee of the
Company's Board of Directors (the Board Committee), including restricted stock,
stock options, stock bonus shares, or performance-based shares. The option
recipients and the terms of options granted under these plans are determined by
the Board Committee. As of year-end 1998, only nonqualified stock options have
been awarded under these plans. Generally, options granted to date are
exercisable immediately, but are subject to certain transfer restrictions and
the right of the Company to repurchase shares issued upon exercise of the
options at the exercise price, upon certain events. The restrictions and
repurchase rights generally lapse ratably over a one- to ten-year period,
depending on the term of the option, which may range from five to twelve years.
Nonqualified stock options may be granted at any price determined by the Board
Committee, although incentive stock options must be granted at not less than the
fair market value of the Company's stock on the date of grant. Generally, all
options have been granted at fair market value. The Company also has a
directors' stock option plan that provides for the grant of stock options in the
Company and its majority-owned subsidiaries to outside directors pursuant to a
formula approved by the Company's shareholders. Options in the Company awarded
under this plan are exercisable six months after the date of grant and expire
three or seven years after the date of grant. In addition to the Company's
stock-based compensation plans, certain officers and key employees may also
participate in the stock-based compensation plans of Thermo Electron.
      In November 1998, the Company's employees, excluding its officers and
directors, were offered the opportunity to exchange previously granted options
to purchase shares of Company common stock for an amount of options equal to
half of the number of options previously held, exercisable at a price equal to
the fair market value at the time of the exchange offer. Holders of options to
acquire 669,000 shares at a weighted average exercise price of $29.69 per share
elected to participate in this exchange and, as a result, received options to
purchase 334,000 shares of Company common stock at $13.11 per share, which are
included in the 1998 grants in the table below. The other terms of the new
options are the same as the exchanged options except that the holders may not
sell shares purchased pursuant to such new options for six months from the
exchange date. The options exchanged were canceled by the Company.
      A summary of the Company's stock option activity is:
<TABLE>
<CAPTION>
<S>                                            <C>       <C>        <C>      <C>        <C>       <C>   

                                                       1998                1997                 1996
                                               -------------------  ------------------  ------------
                                                          Weighted            Weighted            Weighted
                                                           Average             Average             Average
                                                          Exercise            Exercise            Exercise
                                                             Price               Price               Price
                                                 Number              Number               Number
                                                     of                  of                   of
(Shares in thousands)                            Shares              Shares               Shares
- ---------------------------------------------- --------- ---------- -------- ---------- --------- ---------

Options Outstanding, Beginning of Year            4,365     $16.83    4,066     $13.98     4,026     $11.88
  Granted                                           698      13.30      727      30.24       472      27.59
  Exercised                                        (325)      9.23     (263)      9.50      (255)      7.31
  Forfeited                                        (181)     17.88     (165)     17.56      (177)     12.00
  Canceled due to exchange                         (669)     29.69        -          -         -         -
                                                  -----                ----                -----

Options Outstanding, End of Year                  3,888     $14.57    4,365     $16.83     4,066     $13.98
                                                  =====     ======    =====     ======     =====     ======

Options Exercisable                               3,886     $14.56    4,365     $16.83     4,066     $13.98
                                                  =====     ======    =====     ======     =====     ======

Options Available for Grant                       2,498               2,346                1,908
                                                  =====               =====                =====

</TABLE>


                                       16
<PAGE>

4.    Employee Benefit Plans (continued)
<TABLE>
<CAPTION>

      A summary of the status of the Company's stock options at January 2, 1999,
is:
<S>                                            <C>                  <C>                 <C>   

                                                                       Options Outstanding
                                                      ------------------------------------------------------
Range of Exercise Prices                                   Number             Weighted             Weighted
                                                               of              Average              Average
                                                           Shares            Remaining             Exercise
                                                   (In thousands)     Contractual Life                Price
- ---------------------------------------------- -------------------- ------------------- --------------------
$  6.51 - $ 12.72                                             844            4.3 years              $11.53
  12.73 -   18.93                                           2,631            6.8 years               13.34
  25.15 -   31.35                                             413            7.3 years               28.63
                                                           ------

$  6.51 - $ 31.35                                           3,888            6.3 years              $14.57
                                                            =====

      The information disclosed above for options outstanding at January 2,
1999, does not differ materially for options exercisable.

Employee Stock Purchase Program
      Substantially all of the Company's full-time U.S. employees are eligible
to participate in an employee stock purchase program sponsored by the Company
and Thermo Electron. Prior to the 1998 program year, shares of the Company's and
Thermo Electron's common stock could be purchased at the end of a 12-month
period at 95% of the fair market value at the beginning of the period and the
shares purchased were subject to a six-month resale restriction. Effective
November 1, 1998, the applicable shares of common stock may be purchased at 85%
of the lower of the fair market value at the beginning or end of the plan year,
and shares purchased are subject to a one-year resale restriction. Shares are
purchased through payroll deductions of up to 10% of each participating
employee's gross wages. No shares were issued under this program during 1998.
During 1997 and 1996, the Company issued 52,000 shares and 62,000 shares,
respectively, of its common stock under this program.

Pro Forma Stock-based Compensation Expense
     In October 1995, the Financial  Accounting  Standards Board issued SFAS No.
123,  "Accounting for Stock-based  Compensation,"  which sets forth a fair-value
based method of recognizing  stock-based  compensation  expense. As permitted by
SFAS No. 123, the Company has elected to continue to apply APB No. 25 to account
for its stock-based compensation plans. Had compensation cost for awards granted
after 1994 under the Company's stock-based
</TABLE>


                                       17
<PAGE>

4.    Employee Benefit Plans (continued)
<TABLE>
<CAPTION>

compensation plans been determined based on the fair value at the grant dates
consistent with the method set forth under SFAS No. 123, the effect on the
Company's net income and earnings per share would have been:
<S>                                                                        <C>        <C>        <C>      

(In thousands except per share amounts)                                         1998       1997       1996
- -------------------------------------------------------------------------- ---------- ---------- ----------

Net Income:
  As reported                                                              $ 104,084  $ 147,258  $ 132,751
  Pro forma                                                                   96,922    143,083    129,591

Basic Earnings per Share:
  As reported                                                                    .86       1.21       1.12
  Pro forma                                                                      .80       1.18       1.09

Diluted Earnings per Share:
  As reported                                                                    .79       1.09       1.01
  Pro forma                                                                      .74       1.06        .99

      Because the method prescribed by SFAS No. 123 has not been applied to
options granted prior to January 1, 1995, the resulting pro forma compensation
expense may not be representative of the amount to be expected in future years.
Pro forma compensation expense for options granted is reflected over the vesting
period; therefore, future pro forma compensation expense may be greater as
additional options are granted.
      The weighted average fair value per share of options granted was $3.93,
$11.09, and $10.90 in 1998, 1997, and 1996, respectively. The fair value of each
option grant was estimated on the grant date using the Black-Scholes
option-pricing model with the following weighted-average assumptions:

                                                                                1998       1997       1996
- -------------------------------------------------------------------------- ---------- ---------- ----------

Volatility                                                                       29%        28%        26%
Risk-free Interest Rate                                                         4.5%       5.9%       6.2%
Expected Life of Options                                                   3.8 years  5.2 years  6.2 years

      The Black-Scholes option-pricing model was developed for use in estimating
the fair value of traded options, which have no vesting restrictions and are
fully transferable. In addition, option-pricing models require the input of
highly subjective assumptions, including expected stock price volatility.
Because the company's employee stock options have characteristics significantly
different from those of traded options, and because changes in the subjective
input assumptions can materially affect the fair value estimate, in management's
opinion, the existing models do not necessarily provide a reliable single
measure of the fair value of its employee stock options.

401(k) Savings Plans
      The majority of the Company's full-time U.S. employees are eligible to
participate in Thermo Electron's 401(k) savings plan. Contributions to the
Thermo Electron 401(k) savings plan are made by both the employee and the
Company. Company contributions are based upon the level of employee
contributions. For this plan, the Company contributed and charged to expense
$4.2 million, $6.0 million, and $3.7 million in 1998, 1997, and 1996,
respectively.

                                       18
<PAGE>

4.    Employee Benefit Plans (continued)

Other Retirement Plans
      Certain of the Company's subsidiaries offer other retirement plans in lieu
of participation in the Thermo Electron 401(k) savings plan. Company
contributions to these plans are based on formulas determined by the Company.
For these plans, the Company contributed and charged to expense $7.5 million,
$6.5 million, and $4.2 million in 1998, 1997, and 1996, respectively.

Defined Benefit Pension Plan
      Life Sciences International PLC has a defined benefit pension plan covering substantially all of
its full-time U.K. employees.
      Net periodic benefit income included the following components:

(In thousands)                                                                            1998      1997
- -------------------------------------------------------------------------------------- -------- ---------

Service Cost                                                                           $ 2,523  $  2,749
Interest Cost on Benefit Obligation                                                      3,182     3,031
Expected Return on Plan Assets                                                          (6,337)   (6,239)
                                                                                       -------  --------

                                                                                       $  (632) $   (459)
                                                                                       =======  ========
</TABLE>
<TABLE>
<CAPTION>
<S>                                                                                <C>         <C>     

      The Company's defined benefit plan activity is:

(In thousands)                                                                           1998        1997
- ---------------------------------------------------------------------------------- ----------- -----------

Change in Benefit Obligation:
  Benefit obligation, beginning of year                                              $ 45,890    $ 38,086
  Service cost                                                                          2,523       2,749
  Interest cost                                                                         3,182       3,031
  Benefits paid                                                                        (1,271)     (1,343)
  Actuarial loss                                                                        6,909       3,777
  Currency translation adjustment                                                         673        (410)
                                                                                     --------    --------

  Benefit obligation, end of year                                                      57,906      45,890
                                                                                     --------    --------

Change in Plan Assets:
  Fair value of plan assets, beginning of year                                         63,707      56,273
  Actual return on plan assets                                                         10,857       9,408
  Benefits paid                                                                        (1,271)     (1,343)
  Currency translation adjustment                                                         886        (631)
                                                                                      -------    --------

  Fair value of plan assets, end of year                                               74,179      63,707
                                                                                      -------    --------

Funded Status                                                                          16,273      17,817
Unrecognized Net Actuarial (Gain) Loss                                                  2,233        (172)
                                                                                     --------    --------

Prepaid Pension Costs                                                                $ 18,506    $ 17,645
                                                                                     ========    ========

                                       19
<PAGE>


4.    Employee Benefit Plans (continued)

      Significant actuarial assumptions used to determine the net periodic
pension cost were:

                                                                                          1998       1997
- -------------------------------------------------------------------------- ---------- --------- ----------

Discount Rate                                                                               7%      8.25%
Rate of Increase in Salary Levels                                                         6.5%         8%
Expected Long-term Rate of Return on Assets                                                10%        10%
</TABLE>

5.    Income Taxes
<TABLE>
<CAPTION>
<S>                                                                        <C>        <C>        <C>      

      The components of income before provision for income taxes, minority
interest, and extraordinary item are:

(In thousands)                                                                   1998      1997       1996
- --------------------------------------------------------------------------- ---------- --------- ----------

Domestic                                                                    $ 119,584  $186,133  $ 143,377
Foreign                                                                        74,332    61,884     46,546
                                                                            ---------  --------  ---------

                                                                            $ 193,916  $248,017  $ 189,923
                                                                            =========  ========  =========

      The components of the provision for income taxes are:

(In thousands)                                                                   1998      1997       1996
- --------------------------------------------------------------------------- ---------- --------- ----------

Currently Payable:
  Federal                                                                   $  35,085  $ 47,121  $  29,593
  State                                                                         6,263     8,154      6,978
  Foreign                                                                      30,775    26,242     27,100
                                                                            ---------  --------  ---------

                                                                               72,123    81,517     63,671
                                                                            ---------  --------  ---------

Net Deferred (Prepaid):
  Federal                                                                       2,721     3,860     (5,553)
  State                                                                           304       819     (1,178)
  Foreign                                                                        (474)    1,917     (5,213)
                                                                            ---------  --------  ---------

                                                                                2,551     6,596    (11,944)
                                                                            ---------  --------  ---------

                                                                            $  74,674  $ 88,113  $  51,727
                                                                            =========  ========  =========

      The Company and its majority-owned subsidiaries receive a tax deduction
upon exercise of nonqualified stock options by employees for the difference
between the exercise price and the market price of the underlying common stock
on the date of exercise. The provision for income taxes that is currently
payable does not reflect $1.5 million, $1.6 million, and $2.0 million of such
benefits of the Company and its majority-owned subsidiaries that have been
allocated to capital in excess of par value, directly or through the effect of
majority-owned subsidiaries' equity

                                       20
<PAGE>

5.    Income Taxes (continued)

transactions, in 1998, 1997, and 1996, respectively. The provision for income
taxes that is currently payable does not reflect $4.4 million, $2.4 million, and
$4.7 million of tax benefits used to reduce cost in excess of net assets of
acquired companies in 1998, 1997, and 1996, respectively.
      The provision for income taxes in the accompanying statement of income
differs from the provision calculated by applying the statutory federal income
tax rate of 35% to income before provision for income taxes, minority interest,
and extraordinary item due to:

(In thousands)                                                                  1998       1997       1996
- -------------------------------------------------------------------------- ---------- ---------- ----------

Provision for Income Taxes at Statutory Rate                               $  67,871  $  86,806  $  66,473
Increases (Decreases) Resulting from:
  Gain on issuance of stock by subsidiaries                                   (6,504)   (16,241)   (25,100)
  Foreign tax rate and tax loss differential                                   4,285      6,500      5,596
  State income taxes, net of federal tax                                       4,269      5,832      3,770
  Amortization of cost in excess of net assets of acquired                     5,344      4,492      2,445
   companies
  Tax benefit of foreign sales corporation                                    (2,606)    (2,517)    (2,102)
  Other, net                                                                   2,015      3,241        645
                                                                           ---------  ---------  ---------

                                                                           $  74,674  $  88,113  $  51,727
                                                                           =========  =========  =========

      Prepaid income taxes and deferred income taxes in the accompanying balance
sheet consist of:

(In thousands)                                                                             1998       1997
- ------------------------------------------------------------------------------------- ---------- ----------

Prepaid Income Taxes:
  Tax loss carryforwards                                                              $  51,563  $  43,559
  Inventory basis difference                                                             22,557     13,109
  Reserves and accruals                                                                  27,192     33,717
  Accrued compensation                                                                    7,733      5,306
  Allowance for doubtful accounts                                                         4,358      2,459
                                                                                      ---------  ---------

                                                                                        113,403     98,150
  Less:  Valuation Allowance                                                             51,563     43,235
                                                                                      ---------  ---------

                                                                                      $  61,840  $  54,915
                                                                                      =========  =========

Deferred Income Taxes:
  Depreciation                                                                        $  17,631  $  24,928
  Intangible assets                                                                       7,840      5,502
  Other, net                                                                              3,807          -
                                                                                      ---------  ---------

                                                                                      $  29,278  $  30,430
                                                                                      =========  =========


                                       21
<PAGE>

5.    Income Taxes (continued)

      The valuation allowance relates to uncertainty surrounding the realization
of certain tax assets, including $129.1 million of foreign tax loss
carryforwards and $6.8 million of certain federal tax loss carryforwards in
1998, the realization of which is limited to the future income of certain
subsidiaries. Of the $129.1 million of foreign tax loss carryforwards,
approximately $68 million expire from 1999 through 2006 and the remainder do not
expire. The federal tax loss carryforwards expire from 1999 through 2012. Any
tax benefit resulting from the use of acquired loss carryforwards will be used
to reduce cost in excess of net assets of acquired companies. The increase in
the valuation allowance results primarily from the increase in foreign net
operating loss carryforwards.
      The Company has not recognized a deferred tax liability for the difference
between the book basis and tax basis of its investment in the common stock of
its domestic subsidiaries (such difference relates primarily to unremitted
earnings and gains on issuance of stock by subsidiaries) because the Company
does not expect this basis difference to become subject to tax at the parent
level. The Company believes it can implement certain tax strategies to recover
its investment in its domestic subsidiaries tax-free.
      A provision has not been made for U.S. or additional foreign taxes on
approximately $192 million of undistributed earnings of foreign subsidiaries
that could be subject to taxation if remitted to the U.S. because the Company
plans to keep these amounts permanently reinvested overseas.

6.    Short- and Long-term Obligations

Short-term Obligations
      Notes payable and current maturities of long-term obligations in the
accompanying balance sheet includes $59.4 million and $58.8 million of bank
borrowings at several of the Company's foreign subsidiaries at year-end 1998 and
1997, respectively. Unused lines of credit were $168.9 million at year-end 1998.
Borrowings under lines of credit are generally guaranteed by Thermo Electron.
      In addition, the Company's Netherlands-based subsidiaries have an
agreement with a wholly owned subsidiary of Thermo Electron under which the
subsidiaries can borrow funds that bear interest at a rate based on Netherlands
market rates, set at the beginning of each month. At year-end 1998, the Company
had borrowings under this agreement of $6.1 million, which are included in notes
payable and current maturities of long-term obligations in the accompanying
balance sheet.
      The weighted average interest rate for these borrowings was 3.48% and
4.80% at year-end 1998 and 1997, respectively.
      In June 1997, to finance the repayment of Life Sciences' debt, the Company
borrowed $115.0 million from Thermo Electron, which was repaid in September
1997.

                                       22
<PAGE>

6.    Short- and Long-term Obligations (continued)

Long-term Obligations

(In thousands except per share amounts)                                                     1998      1997
- -------------------------------------------------------------------------------------- ---------- ---------

3 3/4% Senior Convertible Note to Parent Company, Due 2000, Convertible                $ 140,000  $140,000
  at $13.55 Per Share
3 3/4% Senior Convertible Debentures, Due 2000, Convertible at $13.55 Per                 14,542    15,324
  Share
4 1/2% Senior Convertible Debentures, Due 2003, Convertible at $34.46 Per                172,500   172,500
  Share
4% Subordinated Convertible Debentures, Due 2005, Convertible at $35.65 Per              250,000         -
  Share (b)
5% Subordinated Convertible Debentures, Due 2000, Convertible Into Shares of              67,931    80,591
  ThermoQuest at $16.50 Per Share
5% Subordinated Convertible Debentures, Due 2000, Convertible Into Shares of              71,505    79,956
  Thermo Optek at $13.94 Per Share
10.23% Mortgage Loan Secured by Property With a Net Book Value of $14,863,                 7,319     8,343
  Payable in Monthly Installments With Final Payments in 2004
Promissory Note to Parent Company (a) (b)                                                      -   105,000
Promissory Notes to Parent Company From ThermoSpectra, Due 1999 (a)                       60,000    60,000
Promissory Note to Parent Company From Thermo Vision, Due 2000 (a)                         3,800     3,800
Promissory Notes to Parent Company From Thermo Optek and ThermoSpectra,                        -    55,000
  Due August 1998 (a)
Other                                                                                     21,179    10,101
                                                                                       ---------  --------

                                                                                         808,776   730,615
Less:  Current Maturities of Long-term Obligations                                        65,333    57,421
                                                                                       ---------  --------

                                                                                       $ 743,443  $673,194
                                                                                       =========  ========

(a) Bears interest at the 90-day Commercial Paper Composite Rate plus 25 basis
    points, set at the beginning of each quarter. The interest rate for the
    notes outstanding at year-end 1998 and 1997 was 5.36% and 5.76%,
    respectively.
(b) The Company used a portion of the proceeds from the 4% subordinated
    convertible debentures to repay the $105.0 million promissory note to Thermo
    Electron. The $105.0 million promissory note was classified as long-term in
    the accompanying 1997 balance sheet, as its repayment was made using the
    proceeds of debt with a maturity beyond one year.

      The senior convertible debentures are guaranteed on a senior basis by
Thermo Electron. The 4% subordinated convertible debentures of the Company and
the 5% subordinated convertible debentures of ThermoQuest and Thermo Optek are
guaranteed on a subordinated basis by Thermo Electron. The Company has agreed to
reimburse Thermo Electron in the event Thermo Electron is required to make a
payment under the guarantee.
      In lieu of issuing all or a portion of the Company's common stock upon
conversion of the 3 3/4% senior convertible debentures due 2000, the Company has
the option to pay holders of the debentures cash equal to the weighted average
market price of the Company's common stock on the last trading date prior to
conversion.
      The annual requirements for long-term obligations as of January 2, 1999,
are $65.3 million in 1999; $302.6 million in 2000; $4.7 million in 2001; $4.7
million in 2002; $177.2 million 2003; and $254.3 million in 2004 and thereafter.
Total future requirements of long-term obligations are $808.8 million.

                                       23
<PAGE>

6.    Short- and Long-term Obligations (continued)

      During 1998, 1997, and 1996, convertible obligations of $7.6 million,
$38.9 million, and $67.6 million, respectively, were converted into common stock
of the Company or its subsidiaries.
      During 1998, Thermo Optek and ThermoQuest repurchased a total of $14.3
million principal amount of their subordinated convertible debentures for $13.3
million in cash, resulting in an extraordinary gain of $0.5 million, net of
taxes and minority interest of $0.4 million. The extraordinary gain recorded by
the Company did not affect the reported amounts of 1998 basic and diluted
earnings per share.
      See Note 12 for the fair value information pertaining to the Company's
long-term obligations.

7.    Commitments and Contingencies

Operating Leases
      The Company leases portions of its office and operating facilities under
various operating lease arrangements. The accompanying statement of income
includes expenses from operating leases of $32.4 million, $28.2 million, and
$21.1 million in 1998, 1997, and 1996, respectively. Future minimum payments due
under noncancelable operating leases at January 2, 1999, are $25.0 million in
1999; $21.0 million in 2000; $16.6 million in 2001; $13.5 million in 2002; $11.9
million in 2003; and $31.5 million in 2004 and thereafter. Total future minimum
lease payments are $119.5 million.

Contingencies
      ThermoQuest's Finnigan subsidiary has filed complaints against
Bruker-Franzen Analytik GmbH and its U.S. affiliate, and Hewlett-Packard
Company, for alleged violation of two U.S. patents owned by Finnigan pertaining
to methods used in ion-trap mass spectrometers. One of Finnigan's complaints was
filed in United States District Court and the other was filed with the United
States International Trade Commission (ITC). In April 1998, the ITC determined
that the defendants did not engage in unfair practices in U.S. import trade with
respect to the Finnigan patents, and that the Finnigan patents are invalid
and/or not infringed. Finnigan has appealed the ITC's determination with respect
to one of its patents to the United States Court of Appeals for the Federal
Circuit (CAFC). The CAFC heard arguments in the appeal on March 4, 1999. Bruker
has presented counterclaims alleging that the Finnigan patents are invalid and
unenforceable and are not infringed by the mass spectrometers co-marketed by
Bruker. They also allege that Finnigan has violated antitrust laws by attempting
to maintain a monopoly position and restrain trade through enforcement of
allegedly fraudulently obtained patents. Bruker has asked for judgment
consistent with its counterclaims, and for three times the antitrust damages
(including attorney's fees) it has sustained.
      Although the Company intends to vigorously defend this matter, there can
be no assurance as to its outcome. In the opinion of management, while an
unfavorable resolution of this matter could materially affect the Company's
results of operations and cash flows in a particular quarter or year, any such
resolution would not have a material adverse effect on the Company's financial
position.
      The Company is also contingently liable with respect to certain other
lawsuits and matters which, in the opinion of management, will not have a
material effect upon the financial position of the Company or its results of
operations.

Letters of Credit
      Outstanding letters of credit, principally related to performance bond
obligations, totaled $36.5 million at January 2, 1999.

                                       24
<PAGE>

8.    Related-party Transactions

Corporate Services Agreement
      The Company and Thermo Electron have a corporate services agreement under
which Thermo Electron's corporate staff provides certain administrative
services, including certain legal advice and services, risk management, certain
employee benefit administration, tax advice and preparation of tax returns,
centralized cash management, and certain financial and other services, for which
the Company currently pays Thermo Electron annually an amount equal to 0.8% of
the Company's revenues. In 1997 and 1996, the Company paid an amount equal to
1.0% of the Company's revenues. For these services, the Company was charged
$13.3 million, $15.9 million, and $12.1 million in 1998, 1997, and 1996,
respectively. The fee is reviewed and adjusted annually by mutual agreement of
the parties. Management believes that the service fee charged by Thermo Electron
is reasonable and that such fees are representative of the expenses the Company
would have incurred on a stand-alone basis. The corporate service agreement is
renewed annually but can be terminated upon 30 days' prior notice by the Company
or upon the Company's withdrawal from the Thermo Electron Corporate Charter (the
Thermo Electron Corporate Charter defines the relationship among Thermo Electron
and its majority-owned subsidiaries). For additional items such as employee
benefit plans, insurance coverage, and other identifiable costs, Thermo Electron
charges the Company based upon costs attributable to the Company.

Repurchase Agreements
      The Company invests excess cash in repurchase agreements and a notional
pool arrangement with Thermo Electron as discussed in Note 1.

Short- and Long-term Obligations
      See Note 6 for short- and long-term obligations of the Company held by
Thermo Electron.

9.    Common Stock

      At January 2, 1999, the Company had reserved 30,254,000 unissued shares of
its common stock for possible issuance under stock-based compensation plans and
for issuance upon possible conversion of the Company's convertible obligations.

10.   Issuance of Stock by Subsidiaries

      Gain on issuance of stock by subsidiaries in the accompanying statement of
income results from the following transactions:

1998
      Sale of 2,450,000 shares of Thermo BioAnalysis common stock in a public
offering at $18.125 per share for net proceeds of $41.5 million resulted in a
gain of $5.9 million. In addition, in the same offering, Thermo BioAnalysis sold
1,000,000 shares of its common stock to Thermo Electron for proceeds, net of
commissions, of $17.5 million, for which no gain was recognized.
      Sale of 3,300,000 shares of ONIX Systems common stock in an initial public
offering at $14.50 per share for net proceeds of $43.7 million resulted in a
gain of $10.0 million.
      Conversion of $1.8 million of Thermo Optek 5% subordinated convertible
debentures, convertible at $13.94 per share, into 127,646 shares of Thermo Optek
common stock resulted in a gain of $0.9 million.
      Conversion of $4.0 million of ThermoQuest 5% subordinated convertible
debentures, convertible at $16.50 per share, into 239,393 shares of ThermoQuest
common stock resulted in a gain of $1.8 million.

                                       25
<PAGE>

10.   Issuance of Stock by Subsidiaries (continued)

1997
      Sale of 1,768,500 shares of ThermoQuest common stock at $15.00 per share
for net proceeds of $24.8 million and conversion of $15.7 million of ThermoQuest
5% subordinated convertible debentures, convertible at $16.50 per share, into
949,027 shares of ThermoQuest common stock resulted in gains of $12.0 million
and $7.8 million, respectively.
      Initial public offering of 2,300,000 shares of Metrika Systems common
stock at $15.50 per share for net proceeds of $32.5 million resulted in a gain
of $13.2 million.
      Private placements of 1,639,640 shares of ONIX Systems common stock at
$14.25 per share for net proceeds of $22.0 million resulted in a gain of $7.9
million.
      Conversion of $13.1 million and $3.2 million of Thermo Optek 5%
subordinated convertible debentures, convertible at $14.85 per share and $13.94
per share, respectively, into 1,111,316 shares of Thermo Optek common stock
resulted in a gain of $3.2 million.
      Initial public offering of 1,139,491 shares of Thermo Vision common stock
at $7.50 per share for net proceeds of $7.0 million resulted in a gain of $2.3
million.

1996
      Initial public offering of 3,450,000 shares of ThermoQuest common stock at
$15.00 per share for net proceeds of $47.8 million resulted in a gain of $27.2
million.
      Initial public offering of 3,450,000 shares of Thermo Optek common stock
at $13.50 per share for net proceeds of $42.9 million resulted in a gain of
$25.1 million.
      Initial public offering of 1,670,000 shares of Thermo BioAnalysis common
stock at $14.00 per share for net proceeds of $20.8 million resulted in a gain
of $9.8 million.
      Private placement of 967,828 shares of Metrika Systems common stock at
$15.00 per share for net proceeds of $13.5 million resulted in a gain of $9.6
million.
      The Company's ownership percentages of its majority-owned subsidiaries at
year end were:

                                                                                1998       1997       1996
- -------------------------------------------------------------------------- ---------- ---------- ----------

ThermoSpectra                                                                    82%        77%        72%
ThermoQuest                                                                      89%        88%        93%
Thermo Optek                                                                     93%        91%        93%
Thermo BioAnalysis                                                               62%        70%        67%
Metrika Systems                                                                  67%        60%        84%
Thermo Vision (a)                                                                78%        78%        93%
ONIX Systems                                                                     80%        87%       100%

(a) Thermo Vision was a wholly owned subsidiary of Thermo Optek until December
    1997, when Thermo Optek distributed to its shareholders 100% of the common
    stock of Thermo Vision in the form of a dividend.

                                       26
<PAGE>

11.   Restructuring and Nonrecurring (Income) Expense, Net

      During 1998, the Company and its subsidiaries recorded restructuring and
related costs and other nonrecurring costs of $31.8 million, including
restructuring costs of $21.6 million, an inventory write-down of $8.6 million,
and other nonrecurring costs of $1.6 million.
      Restructuring costs of $21.6 million, which were accounted for in
accordance with EITF 94-3, consist of $16.2 million related to severance costs
for approximately 780 employees across all functions, $4.2 million related
primarily to facility-closing costs, $0.8 million for the write-off of cost in
excess of net assets of acquired companies for a business that was closed, and
$0.4 million related to the loss on the sale of a division. The charge for
facility-closing costs includes $2.0 million for write-downs of related fixed
assets. In addition, the Company recorded $8.6 million of inventory write-downs,
included in cost of revenues in the accompanying statement of income, related to
discontinuing certain product lines and increased excess and obsolescence
reserves associated with lower product demand.
      In connection with these actions, the Company expects to incur additional
costs in early 1999 totaling $2.4 million, for costs not permitted as charges in
1998, pursuant to EITF No. 94-3. These costs primarily include costs for certain
employee relocation, moving, and related costs.
      The Company expects to complete the implementation of its restructuring
plan in 1999. As of year-end 1998, the Company had terminated approximately 500
employees and had expended $7.4 million of the established reserves. The
remaining liability for severance and facility-closing costs of $11.2 million,
as adjusted for the impact of currency translation, is included in other accrued
expenses in the accompanying 1998 balance sheet.
      In December 1996, five former employees of the Company's Epsilon
Industrial, Inc. subsidiary sought damages in an arbitration proceeding for
alleged breaches of agreements entered into with such employees prior to
Epsilon's acquisition by the Company. The arbitrators rendered a decision with
respect to such claims during 1998 and the Company recorded $1.6 million of
nonrecurring costs related to the resolution of this matter.
      Nonrecurring income, net in 1997 reflects a gain of $2.2 million
recognized by ThermoSpectra on the sale of its Linac business for $5.0 million
in cash and $2.1 million in equity securities, offset in part by a $0.9 million
charge incurred by ThermoSpectra, primarily related to severance expense for 40
employees terminated during the year.
      Nonrecurring expense in 1996 reflects the write-off of in-process
technology relating to the acquisition of the Fisons businesses (Note 3).

12.   Fair Value of Financial Instruments

      The Company's financial instruments consist primarily of cash and cash
equivalents, available-for-sale investments, accounts receivable, notes payable
and current maturities of long-term obligations, accounts payable, due to parent
company and affiliated companies, long-term obligations, and forward exchange
contracts. The carrying amounts of these financial instruments, with the
exception of available-for-sale investments, long-term obligations, and forward
foreign exchange contracts, approximate fair value due to their short-term
nature.
      Available-for-sale investments are carried at fair value in the
accompanying balance sheet. The fair values were determined based on quoted
market prices (Note 2).
</TABLE>

                                       27
<PAGE>

12.   Fair Value of Financial Instruments (continued)
<TABLE>
<CAPTION>
<S>                                                            <C>       <C>         <C>        <C>      

      The carrying amounts and fair value of the Company's long-term obligations
and off-balance-sheet financial instruments are:

                                                                        1998                  1997
                                                               --------------------  ----------------------
                                                                Carrying       Fair   Carrying        Fair
(In thousands)                                                    Amount      Value     Amount       Value
- -------------------------------------------------------------- ---------- ---------- ---------- -----------

Long-term Obligations:
  Convertible obligations                                       $716,478   $668,978   $488,371   $ 767,769
  Other                                                           26,965     29,440    184,823     186,653
                                                                --------   --------   --------   ---------

                                                                $743,443   $698,418   $673,194   $ 954,422
                                                                ========   ========   ========   =========

Off-balance-sheet Financial Instruments:
  Forward exchange contracts receivable (payable)                         $    (828)             $     923

      The fair value of long-term obligations was determined based on quoted
market prices and on borrowing rates available to the Company at the respective
year-ends.
      The notional amounts of forward foreign exchange contracts outstanding
totaled $28.4 million and $33.1 million at year-end 1998 and 1997, respectively.
The fair value of such contracts is the estimated amount that the Company would
receive or pay if it were to terminate the contracts, taking into account the
change in foreign exchange rates.

13.   Business Segment and Geographical Data

      The Company's businesses operate in four instrumentation segments:
Analytical, Life Sciences, Process Control, and Industrial. The Analytical
segment, which includes Thermo Optek (excluding Thermo Vision for the periods
prior to its December 1997 spinout) and ThermoQuest, develops and manufactures
analytical instruments that are used in the quantitative and qualitative
analysis of elements and molecular compounds in gases, liquids, and solids. The
Life Sciences segment includes Thermo BioAnalysis (excluding its Eberline Heath
Physics business for periods prior to July 1998, when Thermo BioAnalysis
contributed this business to a joint venture in the Industrial segment). This
segment develops, manufactures, and markets a broad range of products, including
biomolecular instruments and consumables, clinical laboratory equipment and
supplies, rapid point-of-care diagnostic test kits, and laboratory
information-management systems used in biochemical research, clinical diagnosis,
and pharmaceutical production. The Process Control segment, consisting of
Metrika Systems and ONIX Systems, specializes in on-line instruments that
measure and control products such as oil, gas, chemicals, raw materials, and
finished goods throughout a variety of industrial processes. The Industrial
segment, which generally includes Thermo Vision, ThermoSpectra, and the
Company's wholly owned subsidiaries, provides components and systems for
applications such as test and measurement, environmental and nuclear monitoring,
and imaging and inspection.

                                       28
<PAGE>

13.   Business Segment and Geographical Data (continued)

(In thousands)                                                                 1998        1997        1996
- ------------------------------------------------------------------------ ----------- ----------- -----------

Business Segment Information
Revenues:
  Analytical                                                             $  874,704  $  906,863  $  724,276
  Life Sciences                                                             219,949     185,415      56,840
  Process Control                                                           223,682     178,239     147,363
  Industrial                                                                359,076     344,963     283,503
  Intersegment sales eliminations (a)                                       (17,430)    (23,166)     (2,620)
                                                                         ----------  ----------  ----------

                                                                         $1,659,981  $1,592,314  $1,209,362
                                                                         ==========  ==========  ==========

Income Before Provision for Income Taxes, Minority Interest,
and   Extraordinary Item:
  Analytical                                                             $  127,883  $  147,469  $   93,764
  Life Sciences                                                              19,677      20,654        (774)
  Process Control                                                            20,409      23,092      15,199
  Industrial                                                                 18,625      29,158      21,484
  Corporate (b)                                                              (1,174)     (1,119)     (3,030)
                                                                         ----------  ----------  ----------

  Total operating income                                                    185,420     219,254     126,643
  Interest and other income, net                                              8,496      28,763      63,280
                                                                         ----------  ----------  ----------

                                                                         $  193,916  $  248,017  $  189,923
                                                                         ==========  ==========  ==========

Total Assets:
  Analytical                                                             $1,200,259  $1,170,893  $1,122,600
  Life Sciences                                                             395,394     314,236     112,747
  Process Control                                                           286,021     262,661     170,831
  Industrial                                                                490,554     456,930     320,464
  Corporate (c)                                                             193,546     146,433     197,758
                                                                         ----------  ----------  ----------

                                                                         $2,565,774  $2,351,153  $1,924,400
                                                                         ==========  ==========  ==========

Depreciation and Amortization:
  Analytical                                                             $  30,289  $   29,970  $   23,514
  Life Sciences                                                             10,707       8,758       2,379
  Process Control                                                            6,147       4,588       4,198
  Industrial                                                                14,218      11,586       9,784
  Corporate                                                                     68          91       4,358
                                                                         ---------  ----------  ----------

                                                                         $  61,429  $   54,993  $   44,233
                                                                         =========  ==========  ==========

                                       29
<PAGE>

13.   Business Segment and Geographical Data (continued)

(In thousands)                                                                1998        1997        1996
- ------------------------------------------------------------------------ ---------- ----------- -----------

Capital Expenditures:
  Analytical                                                             $  15,301  $   11,979  $    9,143
  Life Sciences                                                              7,607       4,317       1,287
  Process Control                                                            2,201       2,610       2,148
  Industrial                                                                 5,773      10,259       6,386
  Corporate                                                                     20          33         170
                                                                         ---------  ----------  ----------

                                                                         $  30,902  $   29,198  $   19,134
                                                                         =========  ==========  ==========

Geographical Information
Revenues (d):
  United States                                                          $1,067,995 $1,010,964  $  688,865
  England                                                                  281,431     296,570     227,375
  Germany                                                                  176,584     172,696     182,958
  Other                                                                    400,035     380,179     326,600
  Transfers among geographical areas (a)                                  (266,064)   (268,095)   (216,436)
                                                                         ---------  ----------  ----------

                                                                         $1,659,981 $1,592,314  $1,209,362
                                                                         ==========  ==========  ==========

Long-lived Assets (e):
  United States                                                          $ 145,981  $  146,978  $  107,220
  England                                                                   19,814      23,444      23,861
  Germany                                                                   24,197      23,264      29,701
  Other                                                                     34,942      30,142      25,508
                                                                         ---------  ----------  ----------

                                                                         $ 224,934  $  223,828  $  186,290
                                                                         =========  ==========  ==========

Export Revenues Included in United States Revenues Above (f)             $ 342,796  $  334,853  $  253,705
                                                                         =========  ==========  ==========

(a) Intersegment sales and transfers among geographical areas are accounted for
    at prices that are representative of transactions with unaffiliated parties.
(b) Primarily corporate general and administrative expenses. 
(c) Primarily cash, cash equivalents, and available-for-sale investments. 
(d) Revenues are attributed to countries based on selling location. 
(e) Includes property, plant, and equipment, net and other long-term tangible assets. 
(f) In general, export revenues are denominated in U.S. dollars.

                                       30
<PAGE>

14.   Comprehensive Income

      During the first quarter of 1998, the Company adopted SFAS No. 130,
"Reporting Comprehensive Income." This pronouncement sets forth requirements for
disclosure of the Company's comprehensive income and accumulated other
comprehensive items. In general, comprehensive income combines net income and
"other comprehensive items," which represents certain amounts that are reported
as components of shareholders' investment in the accompanying balance sheet,
including foreign currency translation adjustments and unrealized net of tax
gains and losses on available-for-sale investments.
      Accumulated other comprehensive items in the accompanying balance sheet
consists of:

(In thousands)                                                                             1998       1997
- ------------------------------------------------------------------------------------- ---------- ----------

Cumulative Translation Adjustment                                                     $ (10,340) $ (33,257)
Net Unrealized Gains (Losses) on Available-for-sale Investments                            (874)        36
                                                                                      ---------  ---------

                                                                                      $ (11,214) $ (33,221)
                                                                                      =========  =========

      Unrealized gains (losses) on available-for-sale investments, which is also
a component of other comprehensive items in the accompanying statement of
comprehensive income and shareholders' investment, includes:

(In thousands)                                                                  1998       1997       1996
- -------------------------------------------------------------------------- ---------- ---------- ----------

Unrealized Holding Gains (Losses) Arising During the Year (net             $    (454) $      22  $      14
  of income tax (provision) benefit of $219, $3, and $(8))
Reclassification Adjustment for Gains Included in Net Income                    (456)         -          -
  (net of income tax provision of $257 in 1998)
                                                                           ---------  ---------  ---------

Net Unrealized Gains (Losses) (net of income tax (provision)               $    (910) $      22  $      14
  benefit of $476, $3, and $(8))
                                                                           =========  =========  =========



                                       31
<PAGE>

15.   Earnings per Share

      Basic and diluted earnings per share were calculated as follows:

(In thousands except per share amounts)                                          1998      1997       1996
- --------------------------------------------------------------------------- ---------- --------- ----------

Basic
Net Income                                                                  $ 104,084  $147,258  $ 132,751
                                                                            ---------  --------  ---------

Weighted Average Shares                                                       120,975   121,548    118,857
                                                                            ---------  --------  ---------

Basic Earnings per Share                                                    $     .86  $   1.21  $    1.12
                                                                            =========  ========  =========

Diluted
Net Income                                                                  $ 104,084  $147,258  $ 132,751
Effect of:
  Convertible obligations                                                       3,423     8,089      5,288
  Majority-owned subsidiaries' dilutive securities                             (2,343)   (2,839)      (922)
                                                                            ---------  --------  ---------

Income Available to Common Shareholders, as Adjusted                        $ 105,164  $152,508  $ 137,117
                                                                            ---------  --------  ---------

Weighted Average Shares                                                       120,975   121,548    118,857
Effect of:
  Convertible obligations                                                      11,422    16,713     15,292
  Stock options                                                                   706     1,154      1,202
                                                                            ---------  --------  ---------

Weighted Average Shares, as Adjusted                                          133,103   139,415    135,351
                                                                            ---------  --------  ---------

Diluted Earnings per Share                                                  $     .79  $   1.09  $    1.01
                                                                            =========  ========  =========

      The computation of diluted earnings per share for 1998 excludes the effect
of assuming the conversion of the Company's $172.5 million principal amount 4
1/2% senior convertible debentures, convertible at $34.46 per share, and $250.0
million principal amount 4% subordinated convertible debentures, convertible at
$35.65 per share, because the effect would be antidilutive.
      In addition, the computation of diluted earnings per share for 1998
excludes the effect of assuming the exercise of certain outstanding stock
options because the effect would be antidilutive. As of January 2, 1999, there
were 3,044,000 of such options outstanding, with exercise prices ranging from
$12.91 to $31.35 per share.
      The extraordinary gain recorded by the Company in 1998 (Note 6) did not
affect the reported amounts of 1998 basic and diluted earnings per share.

                                       32
<PAGE>

16.   Unaudited Quarterly Information

(In thousands except per share amounts)

1998                                                                First     Second      Third     Fourth
- ---------------------------------------------------------------- --------- ---------- ---------- ----------

Revenues                                                         $407,943   $395,392   $407,010   $449,636
Gross Profit                                                      193,734    190,717    176,776    209,179
Income Before Extraordinary Item                                   37,855     37,596      2,882     25,232
Net Income (a)                                                     37,855     37,596      3,077     25,556
Earnings per Share (a):
  Basic                                                               .31        .31        .03        .21
  Diluted                                                             .28        .28        .03        .20

1997                                                                First     Second      Third     Fourth
- ---------------------------------------------------------------- --------- ---------- ---------- ----------

Revenues                                                         $329,120   $405,235   $403,900   $454,059
Gross Profit                                                      155,672    194,741    188,901    210,991
Net Income                                                         33,587     37,219     37,273     39,179
Earnings per Share:
  Basic                                                               .28        .31        .31        .32
  Diluted                                                             .25        .28        .28        .29

(a) Reflects an extraordinary item of $0.2 million and $0.3 million in the third
    quarter and fourth quarter, respectively, net of taxes and minority
    interest. The extraordinary item increased diluted earnings per share by
    $.01 in the fourth quarter.

17.   Proposed Reorganization

      During 1998, Thermo Electron announced a proposed reorganization involving
certain of Thermo Electron's subsidiaries, including the Company. As part of
this reorganization, ThermoSpectra may be taken private. The public shareholders
of ThermoSpectra would receive cash in exchange for their shares of common stock
of ThermoSpectra. The completion of this transaction is subject to numerous
conditions, including the establishment of prices; confirmation of anticipated
tax consequences; the approval of the boards of directors (including the
independent directors) of ThermoSpectra and the Company; the negotiation and
execution of a definitive agreement; the receipt of a fairness opinion from an
investment banking firm on certain financial aspects of the transaction; and
clearance by the Securities and Exchange Commission of any necessary documents
regarding the proposed transaction. This transaction may not occur if the
applicable conditions described above are not satisfied.

                                       33
<PAGE>


18.   Subsequent Event

      On February 22, 1999, the Company declared unconditional in all respects
its cash tender offer for all outstanding shares of Spectra-Physics AB, a
Stockholm Stock Exchange-listed company, for 160 Swedish krona per share
(approximately $20 per share). As of that date, the Company had acquired or
received acceptances representing approximately 98% of the Spectra-Physics
shares outstanding. There are approximately 17.6 million Spectra-Physics shares
outstanding. The aggregate cost for Spectra-Physics will total approximately
$355 million. Payment was made for all shares as to which acceptances had been
received by March 1, 1999. To finance this acquisition, the Company used a
combination of available cash and $200.0 million of borrowings from Thermo
Electron, pursuant to a promissory note due August 1999. The promissory note
bears interest at a variable commercial paper-based rate, which is initially
5.03%. The acquisition will be accounted for using the purchase method of
accounting and its results will be included in the Company's results from the
date of acquisition. Spectra-Physics manufactures a wide range of laser-based
instrumentation systems, primarily for the process-control, industrial
measurement, construction, research, commercial, and government markets.
Spectra-Physics had revenues of approximately $442 million in 1998, with
operations throughout North America and Europe, and a presence in the Pacific
Rim.


                                       34
<PAGE>

                    Report of Independent Public Accountants
To the Shareholders and Board of Directors of Thermo Instrument Systems Inc.:

      We have audited the accompanying consolidated balance sheet of Thermo
Instrument Systems Inc. (a Delaware corporation and 85%-owned subsidiary of
Thermo Electron Corporation) and subsidiaries as of January 2, 1999, and January
3, 1998, and the related consolidated statements of income, cash flows, and
comprehensive income and shareholders' investment for each of the three years in
the period ended January 2, 1999. These consolidated financial statements are
the responsibility of the Company's management. Our responsibility is to express
an opinion on these consolidated financial statements based on our audits.
      We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the consolidated financial statements are
free of material misstatement. An audit includes examining, on a test basis,
evidence supporting the amounts and disclosures in the financial statements. An
audit also includes assessing the accounting principles used and significant
estimates made by management, as well as evaluating the overall financial
statement presentation. We believe that our audits provide a reasonable basis
for our opinion.
      In our opinion, the consolidated financial statements referred to above
present fairly, in all material respects, the financial position of Thermo
Instrument Systems Inc. and subsidiaries as of January 2, 1999, and January 3,
1998, and the results of their operations and their cash flows for each of the
three years in the period ended January 2, 1999, in conformity with generally
accepted accounting principles.



                                                            Arthur Andersen LLP



Boston, Massachusetts 
February 16, 1999 (except with respect to the matter
discussed in Note 18, as to which the date is March 1, 1999)


                                       35
<PAGE>

                     Management's Discussion and Analysis of
                  Financial Condition and Results of Operations

      Forward-looking statements, within the meaning of Section 21E of the
Securities Exchange Act of 1934, are made throughout this Management's
Discussion and Analysis of Financial Condition and Results of Operations. For
this purpose, any statements contained herein that are not statements of
historical fact may be deemed to be forward-looking statements. Without limiting
the foregoing, the words "believes," "anticipates," "plans," "expects," "seeks,"
"estimates," and similar expressions are intended to identify forward-looking
statements. There are a number of important factors that could cause the results
of the Company to differ materially from those indicated by such forward-looking
statements, including those detailed immediately after this Management's
Discussion and Analysis of Financial Condition and Results of Operations under
the heading "Forward-looking Statements."

Overview

      Thermo Instrument Systems Inc. (the Company) is a worldwide leader in the
development, manufacture, and marketing of measurement instruments used to
monitor, collect, and analyze information. These systems are used for multiple
applications in a range of industries, including industrial processing, food and
beverage production, life sciences research, and medical diagnostics.
      The Company's businesses operate in four instrumentation segments:
Analytical, Life Sciences, Process Control, and Industrial. The Analytical
segment, which includes the Company's Thermo Optek Corporation (excluding Thermo
Vision Corporation for the periods prior to its December 1997 spinout) and
ThermoQuest Corporation subsidiaries, develops and manufactures analytical
instruments that are used in the quantitative and qualitative analysis of
elements and molecular compounds in gases, liquids, and solids. The Life
Sciences segment includes Thermo BioAnalysis Corporation (excluding its Eberline
Health Physics business for periods prior to July 1998, when it contributed this
business to a joint venture in the Industrial segment). This segment develops,
manufactures, and markets a broad range of products, including biomolecular
instruments and consumables, clinical laboratory equipment and supplies, rapid
point-of-care diagnostic test kits, and laboratory information-management
systems used in biochemical research, clinical diagnosis, and pharmaceutical
production. The Process Control segment, consisting of the Company's Metrika
Systems Corporation and ONIX Systems Inc. subsidiaries, specializes in on-line
instruments that measure and control products such as oil, gas, chemicals, raw
materials, and finished goods throughout a variety of industrial processes. The
Industrial segment, which generally includes the Company's Thermo Vision,
ThermoSpectra Corporation, and wholly owned subsidiaries, provides components
and systems for applications such as test and measurement, environmental and
nuclear monitoring, and imaging and inspection.
      International sales account for a significant portion of the Company's
total revenues. Although the Company seeks to charge its customers in the same
currency as its operating costs, the Company's financial performance and
competitive position can be affected by currency exchange rate fluctuations.
Where appropriate, the Company uses short-term forward foreign exchange
contracts to reduce its exposure to currency fluctuations (Note 12).

Results of Operations

1998 Compared With 1997
      Revenues increased $67.7 million to $1,660.0 million in 1998 from $1,592.3
million in 1997, primarily due to acquisitions. Revenues increased $156.6
million due to 1998 acquisitions and the inclusion of revenues from 1997
acquisitions for the full year. The increase in revenues was offset in part by a
decrease of $12.7 million due to the unfavorable effects of currency translation
as a result of the strengthening of the U.S. dollar relative to foreign
currencies in countries in which the Company operates. Excluding the impact of
acquisitions and currency translation, revenues decreased $76.2 million.
      Analytical segment revenues decreased to $874.7 million in 1998 from
$906.9 million in 1997. Revenues decreased $6.7 million due to the unfavorable
effects of currency translation. Revenues from existing operations

                                       36
<PAGE>

1998 Compared With 1997 (continued)
decreased primarily as a result of lower sales to customers in Asia due to
unstable economic conditions in that region and, to a lesser extent, due to
lower sales to customers in the semiconductor industry. These decreases were
offset in part by the inclusion of $36.2 million of revenues from acquisitions.
      Life Sciences segment revenues increased to $219.9 million in 1998 from
$185.4 million in 1997, primarily due to the inclusion of $34.8 million from
acquisitions.
      Process Control segment revenues increased to $223.7 million in 1998 from
$178.2 million in 1997, primarily due to the inclusion of $47.8 million from
acquisitions.
      Industrial segment revenues increased to $359.1 million in 1998 from
$345.0 million in 1997. An increase in revenues of $37.8 million from
acquisitions was offset in part by lower revenues at existing businesses and a
decrease of $5.4 million due to the unfavorable effects of currency translation.
Revenues from existing operations decreased primarily at ThermoSpectra, due to a
downturn in the semiconductor industry and lower sales to customers overseas.
      The Company's backlog decreased $15.4 million during 1998 to $283.5
million. Backlog decreased primarily in the Industrial and Analytical segments,
principally as a result of the slowdown in the semiconductor and related
industries and a decrease in demand in Asia. In addition, Process Control
segment revenues in the first half of 1999 are expected to be adversely impacted
by a decrease in capital spending in the oil and gas and cement industries and
increased competition resulting from the entry of new competitors into the
raw-material marketplace.
      The gross profit margin decreased to 46% in 1998 from 47% in 1997,
primarily due to inventory write-downs of $8.6 million recorded in 1998 for
discontinued product lines and excess inventories caused by lower product demand
(Note 11). The 1997 period included an adjustment to expense of $3.6 million
relating to the sale of inventories revalued at the time of the acquisition of
Life Sciences International PLC and an inventory write-down in the Industrial
segment.
      Selling, general, and administrative expenses as a percentage of revenues
was unchanged at 27% in 1998 and 1997. Research and development expenses
increased to $113.9 million in 1998 from $107.6 million in 1997, primarily due
to the inclusion of expenses at acquired businesses.
      In addition to the inventory write-downs discussed above, the Company
recorded restructuring and nonrecurring costs of $23.2 million in 1998 (Note
11). The Company recorded $21.6 million of restructuring costs, including $16.2
million of severance costs for approximately 780 employees across all functions,
$4.2 million for facility-closing costs, $0.8 million for the write-off of cost
in excess of net assets of acquired companies for a business that was closed,
and $0.4 million for the loss on the sale of a division. The Company expects to
complete the implementation of its restructuring plan in 1999. In connection
with these actions, the Company expects to incur an additional $2.4 million of
costs in early 1999, primarily for employee relocation, moving, and related
costs. The Company also recorded $1.6 million of nonrecurring costs relating to
the resolution of an arbitration proceeding. In 1997, the Industrial segment
recognized a gain of $2.2 million on the sale of ThermoSpectra's Linac business,
which was offset in part by a charge by ThermoSpectra of $0.9 million for
severance costs for employees terminated during 1997 (Note 11).
      Interest income increased to $33.5 million in 1998 from $28.3 million in
1997. This increase was primarily due to interest income earned on invested
proceeds from the Company's January 1998 issuance of $250.0 million principal
amount of 4% subordinated convertible debentures, offset in part by the use of a
portion of the proceeds to repay a $105.0 million promissory note to Thermo
Electron Corporation (Note 6). To a lesser extent, interest income increased due
to higher average invested balances as a result of the sale of common stock by
the Company's subsidiaries in 1998 and 1997.
      Interest expense was relatively unchanged at $45.5 million in 1998 and
$45.9 million in 1997. Increased interest expense due to the issuance of an
aggregate $428.8 million of promissory notes to Thermo Electron in 1997 in
connection with acquisitions and the Company's January 1998 issuance of 4%
subordinated convertible debentures

                                       37
<PAGE>

1998 Compared With 1997 (continued)
(Note 6) was offset in part by the repayment of certain promissory notes to
Thermo Electron issued in connection with acquisitions, and, to a lesser extent,
the conversion of a portion of the Company's and subsidiaries' convertible
obligations into common stock of the Company and its subsidiaries.
      The Company adopted a strategy of spinning out certain of its businesses
into separate subsidiaries and having these subsidiaries sell a minority
interest to outside investors. The Company believes that this strategy provides
additional motivation and incentives for the management of the subsidiaries
through the establishment of subsidiary-level stock option programs, as well as
capital to support the subsidiaries' growth. As a result of the sale of stock by
subsidiaries and issuance of stock by subsidiaries upon conversion of
convertible debentures, the Company recorded gains of $18.6 million in 1998 and
$46.4 million in 1997 (Note 10). These gains represent an increase in the
Company's net investment in the subsidiaries and are classified as "Gain on
issuance of stock by subsidiaries" in the accompanying statement of income. The
size and timing of these transactions are dependent on market and other
conditions that are beyond the Company's control. Accordingly, there can be no
assurance that the Company will be able to generate gains from such transactions
in the future.
      Further, in October 1995, the Financial Accounting Standards Board (FASB)
issued an exposure draft of a Proposed Statement of Financial Accounting
Standards, "Consolidated Financial Statements: Policy and Procedures." In
February 1999, the FASB issued a revision of the earlier document entitled
"Consolidated Financial Statements: Purpose and Policy." The October 1995
exposure draft had proposed new rules for how consolidated financial statements
should be prepared. Under that proposed statement, there would be significant
changes in the way the Company records certain transactions of its controlled
subsidiaries. Among those changes, any sale of the stock of a subsidiary that
does not result in a loss of control would be accounted for in equity of the
consolidated entity with no gain or loss being recorded. The 1995 exposure draft
addressed rule changes concerning consolidation procedures which would affect
the Company's ability to record gains on issuance of subsidiary stock and
consolidation policy, which does not affect the accounting for such gains. The
February 1999 revised exposure draft addresses only consolidation policy. The
FASB has indicated that it will consider resuming discussion on consolidation
procedures after completion of the efforts on consolidation policy. The timing
and content of any final statement on consolidation procedures are uncertain.
      Other income of $1.9 million in 1998 includes a $1.2 million foreign
currency transaction gain at Thermo BioAnalysis, arising from the repayment of a
foreign subsidiary's intercompany borrowings denominated in U.S. dollars. In
addition, other income includes a $0.7 million gain in the Industrial segment
resulting from the 1998 sale by ThermoSpectra of its shares of common stock of
SteriGenics International, which were received in connection with the 1997 sale
of one of its product lines.
      The effective tax rate was 39% in 1998, compared with 36% in 1997.
Excluding the impact of the nontaxable gains on issuance of stock by
subsidiaries in 1998 and 1997, the effective tax rates in both periods exceeded
the statutory federal income tax rate due to nondeductible amortization of cost
in excess of net assets of acquired companies, foreign tax rate and tax law
differences, and the impact of state income taxes. Excluding the impact of the
nontaxable gains, the effective tax rate decreased in 1998, primarily due to
certain foreign tax losses not benefited in the first half of 1997, offset in
part by higher nondeductible amortization.
      Minority interest expense increased to $15.7 million in 1998 from $12.6
million in 1997, primarily due to minority interest associated with the
Company's newly public ONIX Systems and Metrika Systems subsidiaries, the
earnings of certain of the Life Sciences International PLC businesses sold to
ThermoQuest and Thermo Optek in 1997, and the increase in minority ownership as
a result of the 1998 sale of common stock by Thermo BioAnalysis. This increase
was offset in part by lower profits at the Company's majority-owned subsidiaries
as a result of restructuring and related costs recorded in 1998.
      During 1998, two majority-owned subsidiaries repurchased a portion of
their subordinated convertible debentures resulting in an extraordinary gain,
net of taxes and minority interest, of $0.5 million (Note 6).
      See Note 7 for a description of certain legal proceedings involving the
Company.

                                       38
<PAGE>

1997 Compared With 1996
      Revenues increased $382.9 million to $1,592.3 million in 1997 from
$1,209.4 million in 1996. Revenues increased $407 million due to 1997
acquisitions and the inclusion of revenues from 1996 acquisitions for the full
year. This increase in revenues was offset in part by a decrease of $46.8
million due to the unfavorable effects of currency translation as a result of
the strengthening of the U.S. dollar relative to foreign currencies in countries
in which the Company operates. Excluding the impact of acquisitions and currency
translation, revenues increased $22.7 million.
      Analytical segment revenues increased to $906.9 million in 1997 from
$724.3 million in 1996, primarily due to the inclusion of $219.2 million of
revenues from acquisitions, offset in part by a decrease of $37.3 million due to
the unfavorable effects of currency translation. Revenues increased due to
higher sales at ThermoQuest's existing mass spectrometry business, due in part
to the continued success of a new product introduced in the first quarter of
1996. Revenues from Thermo Optek's existing businesses decreased slightly due to
the inclusion in 1996 of several large nonrecurring sales to the Chinese and
Japanese governments, a decrease in demand for elemental products in Japan, and
the elimination of certain unprofitable acquired product lines, offset
substantially by greater demand at one of its business units.
      Life Sciences segment revenues increased to $185.4 million in 1997 from
$56.8 million in 1996, primarily due to the inclusion of $125.8 million from
acquisitions.
      Process Control segment revenues increased to $178.2 million in 1997 from
$147.4 million in 1996. Revenues increased $21.3 million due to acquisitions.
Revenues from existing operations increased at ONIX Systems, primarily due to
increased sales of industry-specific instruments to the production segment of
the oil and gas industry, and at Metrika Systems, primarily as a result of
increased sales in international markets from its on-line raw materials analyzer
business.
      Industrial segment revenues increased to $345.0 million in 1997 from
$283.5 million in 1996. An increase in revenues of $40.4 million from
acquisitions was offset in part by a decrease of $8.5 million due to the
unfavorable effects of currency translation.
      The gross profit margin was 47% in 1997 and 46% in 1996. The increase was
primarily due to margin improvements at certain of the businesses acquired from
Fisons plc in 1996, increased sales of the Analytical segment's higher-margin
mass spectrometry products, and the inclusion in 1996 of an adjustment to
expense of $2.0 million relating to the sale of inventories revalued at the time
of the acquisition of Fisons plc. These increases were offset in part by the
inclusion of lower-margin revenues from acquired businesses, including Life
Sciences International PLC, which recorded an adjustment to expense of $3.6
million in 1997 relating to the sale of inventories revalued at the time of
acquisition and, to a lesser extent, a decrease in the gross profit margin at
ThermoSpectra, primarily as a result of a one-time inventory write-off and a
change in sales mix at one of its business units.
      Selling, general, and administrative expenses as a percentage of revenues
was 27% in 1997 and 28% in 1996. The decrease was primarily due to efforts to
reduce selling and administrative expenses at acquired businesses and, to a
lesser extent, lower selling costs associated with certain of the Life Sciences
International PLC businesses. Research and development expenses increased to
$107.6 million in 1997 from $84.1 million in 1996, primarily due to
acquisitions.
      Restructuring and nonrecurring income, net, in 1997 represents a gain of
$2.2 million recognized by the Industrial segment on the sale of ThermoSpectra's
Linac business, offset in part by a charge by ThermoSpectra of $0.9 million for
severance costs for employees terminated during 1997 (Note 11). In 1996, the
Company wrote off $3.5 million of in-process technology relating to the
acquisition of the Fisons businesses (Note 3).
      Interest income increased to $28.3 million in 1997 from $20.5 million in
1996. The increase was due to interest income earned on invested proceeds from
the Company's October 1996 issuance of $172.5 million principal amount of

                                       39
<PAGE>

1997 Compared With 1996 (continued)
4 1/2% senior convertible debentures and, to a lesser extent, on the invested
proceeds from the sale of common stock by the Company's subsidiaries in 1997 and
1996 (Note 10). The increase in interest income was offset in part by a
reduction in cash as a result of acquisitions.
      Interest expense increased to $45.9 million in 1997 from $28.9 million in
1996. The increase was primarily due to the issuance in 1997 of an aggregate
$428.8 million of promissory notes to Thermo Electron in connection with
acquisitions (Note 6), the Company's October 1996 issuance of 4 1/2% senior
convertible debentures and, to a lesser extent, the inclusion of interest
expense on debt assumed in connection with the acquisitions of the Fisons
businesses and Life Sciences International PLC, which has been subsequently
repaid. In September 1997, the Company repaid $220.0 million of its outstanding
promissory notes to Thermo Electron (Notes 3 and 6). The increase in interest
expense was offset in part by the conversion of a portion of the Company's and
subsidiaries' convertible obligations into common stock of the Company and its
subsidiaries.
      The Company recorded gains from the issuance of subsidiary common stock of
$46.4 million in 1997 and $71.7 million in 1996 (Note 10).
      The effective tax rate was 36% in 1997 and 27% in 1996. The effective tax
rate increased primarily due to a lower nontaxable gain on issuance of stock by
subsidiaries in 1997. Excluding the impact of the gains on issuance of stock by
subsidiaries, the effective tax rates exceeded the statutory federal income tax
rate due to the inability to provide a tax benefit on losses incurred at certain
foreign subsidiaries, the impact of foreign and state income taxes, the
nondeductible amortization of cost in excess of net assets of acquired companies
and, in 1996, the write-off of acquired technology relating to the acquisition
of the Fisons businesses.
      Minority interest expense increased to $12.6 million in 1997 from $5.4
million in 1996, primarily due to higher earnings at Thermo BioAnalysis,
ThermoQuest, and Thermo Optek and, to a lesser extent, minority interest
associated with the Company's Metrika Systems subsidiary. These increases were
offset in part by lower earnings at ThermoSpectra.

Liquidity and Capital Resources

      Consolidated working capital was $746.0 million at January 2, 1999,
compared with $612.7 million at January 3, 1998. Included in working capital are
cash, cash equivalents, and available-for-sale investments of $553.8 million at
January 2, 1999, compared with $477.2 million at January 3, 1998. Of the $553.8
million balance at January 2, 1999, $333.5 million was held by the Company's
majority-owned subsidiaries and the balance was held by the Company and its
wholly owned subsidiaries. Cash provided by operating activities in 1998 was
$171.4 million. The Company generated $10.1 million of cash from a decrease in
inventories, primarily in the Analytical segment, resulting from management
programs to decrease inventories as a result of lower revenues. The Company used
$20.1 million of cash to reduce accounts payable and other current liabilities,
primarily in the Process Control and Analytical segments. The decrease was
primarily due to a decline in customer deposits and commissions, as a result of
lower bookings and revenues, and lower amounts accrued in 1998 for income taxes
and certain employee benefits.
      At January 2, 1999, $150.4 million of the Company's cash and cash
equivalents was held by its foreign subsidiaries. While this cash can be used
outside of the United States, for activities including acquisitions,
repatriation of this cash into the United States would be subject to foreign
withholding taxes and could also be subject to a United States tax.
      The Company's investing activities used $167.3 million of cash in 1998.
The Company expended $148.7 million, net of cash acquired, for acquisitions,
including $19.1 million paid by ONIX Systems to Thermo Power Corporation for the
Peek Measurement Business, acquired effective November 1997 (Note 3). In
addition, the Company expended $30.9 million for purchases of property, plant,
and equipment and received proceeds of $9.5 million from the sale of property,
plant, and equipment in 1998.

                                       40
<PAGE>

Liquidity and Capital Resources (continued)

      The Company's financing activities provided $76.9 million of cash in 1998.
Net proceeds from the issuance of Company and subsidiary common stock totaled
$103.3 million (Note 10). In January 1998, the Company sold at par value $250.0
million principal amount of 4% subordinated convertible debentures due 2005 for
net proceeds of $244.1 million. The Company used a portion of the proceeds to
repay a $105.0 million promissory note to Thermo Electron. In addition, Thermo
Optek and ThermoSpectra repaid $55.0 million of obligations to Thermo Electron.
Thermo Electron has indicated that it will seek repayment of $60.0 million of
notes due to it in 1999 by ThermoSpectra only to the extent ThermoSpectra's cash
flow permits such repayment.
      During 1998, an aggregate principal amount of $7.6 million of the
Company's and subsidiaries' convertible obligations were converted into shares
of Company and subsidiary common stock.
      During 1998, the Company and its majority-owned subsidiaries expended
$119.8 million to purchase common stock of the Company and common stock and
debentures of certain of the Company's majority-owned subsidiaries. These
purchases were made pursuant to authorizations by the Company's and certain
majority-owned subsidiaries' Boards of Directors. As of January 2, 1999, $22.4
million remained under the Company's majority-owned subsidiaries' authorizations
to purchase their securities.
      In 1999, the Company plans to make expenditures of approximately $40
million for property, plant, and equipment.
      Since January 2, 1999, the Company and its majority-owned subsidiaries
have expended approximately $377 million on acquisitions of businesses,
including Spectra-Physics AB, discussed below, and as of March 18, 1999, the
Company and its majority-owned subsidiaries had agreements or nonbinding letters
of intent to acquire new businesses totaling approximately $11 million. Proposed
acquisitions of new businesses are subject to various conditions to closing, and
there can be no assurance that all proposed transactions will be consummated.
The Company believes that its existing resources are sufficient to meet the
capital requirements of its existing operations for the foreseeable future. The
Company has historically complemented internal development with acquisitions of
businesses or technologies that extend the Company's presence in current markets
or provide opportunities to enter and compete effectively in new markets. The
Company will consider making acquisitions of such businesses or technologies
that are consistent with its plans for strategic growth. The Company expects
that it will finance these acquisitions through a combination of internal funds,
and/or short-term borrowings from Thermo Electron although there is no agreement
with Thermo Electron to ensure that funds will be available on acceptable terms
or at all.
      On February 22, 1999, the Company declared unconditional in all respects
its cash tender offer for all outstanding shares of Spectra-Physics AB for 160
Swedish krona per share (approximately $20 per share) (Note 18). As of that
date, the Company had acquired or received acceptances representing
approximately 98% of the Spectra-Physics shares outstanding. There are
approximately 17.6 million Spectra-Physics shares outstanding. The aggregate
cost for Spectra-Physics will total approximately $355 million. Payment was made
for all shares as to which acceptances had been received by March 1, 1999. To
finance this acquisition, the Company used a combination of available cash and
$200.0 million of borrowings from Thermo Electron, pursuant to a promissory note
due August 1999. The Company intends to refinance this obligation through
borrowings from external sources, however, there can be no assurance that the
Company can obtain debt financing on acceptable terms or at all. Thermo Electron
has indicated that it will seek repayment of this note due to it in 1999 only to
the extent the Company's cash flow permits such repayment.

                                       41
<PAGE>

Market Risk

      The Company is exposed to market risk from changes in foreign currency
exchange rates, interest rates, and equity prices, which could affect its future
results of operations and financial condition. The Company manages its exposure
to these risks through its regular operating and financing activities.
Additionally, the Company uses short-term forward contracts to manage certain
exposures to foreign currencies. The Company enters into forward foreign
exchange contracts to hedge firm purchase and sale commitments denominated in
currencies other than its subsidiaries' local currencies. The Company does not
engage in extensive foreign currency hedging activities; however, the purpose of
the Company's foreign currency hedging activities is to protect the Company's
local currency cash flows related to these commitments from fluctuations in
foreign exchange rates. The Company's forward foreign exchange contracts
principally hedge transactions denominated in U.S. dollars, British pounds
sterling, Japanese yen, French francs, and German marks. Gains and losses
arising from forward contracts are recognized as offsets to gains and losses
resulting from the transactions being hedged. The Company does not enter into
speculative foreign currency agreements.

Foreign Currency Exchange Rates
      The Company generally views its investment in foreign subsidiaries with a
functional currency other than the Company's reporting currency as long-term.
The Company's investment in foreign subsidiaries is sensitive to fluctuations in
foreign currency exchange rates. The functional currencies of the Company's
foreign subsidiaries are principally denominated in British pounds sterling,
German marks, Dutch guilders, and French francs. The effect of a change in
foreign currency exchange rates on the Company's net investment in foreign
subsidiaries is reflected in the "Accumulated other comprehensive items"
component of shareholders' investment. A 10% depreciation in year-end 1998
functional currencies, relative to the U.S. dollar, would result in a $58
million reduction of shareholders' investment.
      Forward foreign exchange contracts are sensitive to changes in foreign
currency exchange rates. The fair value of forward foreign exchange contracts is
the estimated amount that the Company would pay or receive upon termination of
the contract, taking into account the change in foreign currency exchange rates.
A 10% depreciation in year-end 1998 foreign currency exchange rates related to
the Company's contracts would result in an increase in the unrealized loss on
forward foreign exchange contracts of $1.5 million. Since the Company uses
forward foreign exchange contracts as hedges of firm purchase and sale
commitments, the unrealized gain or loss on forward foreign currency exchange
contracts resulting from changes in foreign currency exchange rates would be
offset by a corresponding change in the fair value of the hedged item.
      Certain of the Company's cash and cash equivalents are denominated in
currencies other than the functional currency of the depositor and are sensitive
to changes in foreign currency exchange rates. A 10% depreciation in the related
foreign currency exchange rates would result in a negative impact of $1.4
million on the Company's net income.

Interest Rates
      Certain of the Company's available-for-sale investments and long-term
obligations are sensitive to changes in interest rates. Interest rate changes
would result in a change in the fair value of these financial instruments due to
the difference between the market interest rate and the rate at the date of
purchase or issuance of the financial instrument. A 10% decrease in year-end
1998 market interest rates would result in a negative impact to the Company of
$45 million on the net fair value of its interest-sensitive financial
instruments.
      The Company's cash, cash equivalents, and variable-rate short- and
long-term obligations are sensitive to changes in interest rates. Interest rate
changes would result in a change in interest income and expense due to the
difference between the current interest rates on cash, cash equivalents, and the
variable-rate short- and long-term obligations and the rate that these financial
instruments may adjust to in the future. A 10% decrease in year-end 1998
interest rates would result in a negative impact of $1.3 million on the
Company's net income.

                                       42
<PAGE>

Market Risk (continued)

Equity Prices
      The Company's available-for-sale investment portfolio includes equity
securities that are sensitive to fluctuations in price. In addition, the
Company's and its subsidiaries' subordinated convertible debentures are
sensitive to fluctuations in the price of Company or subsidiary common stock
into which the obligations are convertible. Changes in equity prices would
result in changes in the fair value of the Company's available-for-sale
investments and subordinated convertible debentures due to the difference
between the current market price and the market price at the date of purchase or
issuance of the debentures. A 10% increase in the year-end 1998 market equity
prices would result in a negative impact to the Company of $23.9 million on the
net fair value of its price-sensitive equity financial instruments.

Year 2000

      The following information constitutes a "Year 2000 Readiness Disclosure"
under the Year 2000 Information and Readiness Disclosure Act.
      The Company continues to assess the potential impact of the year 2000 on
the Company's internal business systems, products, and operations. The Company's
year 2000 initiatives include (i) testing and upgrading significant information
technology systems and facilities; (ii) testing and developing upgrades, if
necessary, for the Company's current products and certain discontinued products;
(iii) contacting key suppliers and vendors to determine their year 2000
compliance status; and (iv) developing a contingency plan.

The Company's State of Readiness
      The Company has implemented a compliance program to ensure that its
critical information technology systems and facilities will be ready for the
year 2000. The first phase of the program, testing and evaluating the Company's
critical information technology systems and facilities for year 2000 compliance,
has largely been completed. During phase one, the Company tested and evaluated
its significant computer systems, software applications, and related equipment
for year 2000 compliance. The Company also evaluated the potential year 2000
impact on its critical facilities. The Company is currently in phase two of its
program, during which any noncompliant systems or facilities that were
identified during phase one are prioritized and remediated. The Company is
currently upgrading or replacing such noncompliant information technology
systems, and this process was approximately 60% complete as of January 2, 1999.
In many cases, such upgrades or replacements are being made in the ordinary
course of business, without accelerating previously scheduled upgrades or
replacements. The Company expects that all of its material information
technology systems and critical facilities will be year 2000 compliant by
October 1999.
      The Company has also implemented a compliance program to test and evaluate
the year 2000 readiness of the material products that it currently manufactures
and sells. The Company believes that all of such material products are year 2000
compliant. However, as many of the Company's products are complex, interact with
or incorporate third-party products, and operate on computer systems that are
not under the Company's control, there can be no assurance that the Company has
identified all of the year 2000 problems with its current products. The Company
believes that certain of its older products, which it no longer manufactures or
sells, may not be year 2000 compliant. The Company is continuing to test and
evaluate certain of such products. The Company is focusing its efforts on
products that are still under warranty, early in their expected life, and/or
subject to U.S. Food and Drug Administration considerations related to the year
2000. The Company is offering upgrades and/or identifying potential solutions
where reasonably practicable.


                                       43
<PAGE>

Year 2000 (continued)

      The Company is in the process of identifying and contacting suppliers and
vendors that are believed to be significant to the Company's business operations
in order to assess their year 2000 readiness. As part of this effort, the
Company has developed and is distributing questionnaires relating to year 2000
compliance to its significant suppliers and vendors. The Company has started to
follow-up and monitor the year 2000 compliance progress of significant suppliers
and vendors that indicate that they are not year 2000 compliant, or that do not
respond to the Company's questionnaires. The Company has not completed the
majority of its assessment of third-party risk, and expects to be substantially
completed by September 1999.

Contingency Plan
      The Company is developing a contingency plan that will allow its primary
business operations to continue despite disruptions due to year 2000 problems.
This plan may include identifying and securing other suppliers, increasing
inventories, and modifying production facilities and schedules. As the Company
continues to evaluate the year 2000 readiness of its business systems and
facilities, products, and significant suppliers and vendors, it will modify and
adjust its contingency plan as may be required.

Estimated Costs to Address the Company's Year 2000 Issues
      The Company had incurred expenses to third parties (External Costs)
related to year 2000 issues of approximately $2.6 million as of January 2, 1999,
and the total External Costs of year 2000 remediation are expected to be
approximately $5 million. Year 2000 costs were funded from working capital. All
internal costs and related External Costs other than capital additions related
to year 2000 remediation have been and will continue to be expensed as incurred.
      The Company does not track the internal costs incurred for its year 2000
compliance project. Such costs are principally the related payroll costs for its
information systems group.

Risks of the Company's Year 2000 Issues
      While the Company is attempting to minimize any negative consequences
arising from the year 2000 issue, there can be no assurance that year 2000
problems will not have a material adverse impact on the Company's business,
operations, or financial condition. While the Company expects that upgrades to
its internal business systems will be completed in a timely fashion, there can
be no assurance that the Company will not encounter unexpected costs or delays.
Despite its efforts to ensure that its material current products are year 2000
compliant, the Company may see an increase in warranty and other claims,
especially those related to Company products that incorporate, or operate using,
third-party software or hardware. In addition, certain of the Company's older
products, which it no longer manufactures or sells, may not be year 2000
compliant, which may expose the Company to claims. If any of the Company's
material suppliers or vendors experience business disruptions due to year 2000
issues, the Company might also be materially adversely affected. There is
expected to be a significant amount of litigation relating to the year 2000
issue and there can be no assurance that the Company will not incur material
costs in defending or bringing lawsuits. In addition, if any year 2000 issues
are identified, there can be no assurance that the Company will be able to
retain qualified personnel to remedy such issues. Any unexpected costs or delays
arising from the year 2000 issue could have a significant adverse impact on the
Company's business, operations, and financial condition in amounts that cannot
be reasonably estimated at this time.

                                       44
<PAGE>

                           Forward-looking Statements
                                        
      In connection with the "safe harbor" provisions of the Private Securities
Litigation Reform Act of 1995, the Company wishes to caution readers that the
following important factors, among others, in some cases have affected, and in
the future could affect, the Company's actual results and could cause its actual
results in 1999 and beyond to differ materially from those expressed in any
forward-looking statements made by, or on behalf of, the Company.

      Risks Associated With Spinout of Subsidiaries. The Company adopted a
strategy of spinning out certain of its businesses into separate subsidiaries
and having these subsidiaries sell a minority interest to outside investors. As
a result of the sale of stock by subsidiaries, the issuance of stock by
subsidiaries upon conversion of convertible debentures, and similar
transactions, the Company records gains that represent the increase in the
Company's net investment in the subsidiaries. These gains have represented a
substantial portion of the net income reported by the Company in certain
periods. The size and timing of these transactions are dependent on market and
other conditions that are beyond the Company's control. Accordingly, there can
be no assurance that the Company will be able to generate gains from such
transactions in the future.
      Further, in October 1995, the Financial Accounting Standards Board (FASB)
issued an exposure draft of a Proposed Statement of Financial Accounting
Standards, "Consolidated Financial Statements: Policy and Procedures." The
October 1995 exposure draft had proposed new rules for how consolidated
financial statements should be prepared. In February 1999, the FASB issued a
revision of the earlier document entitled "Consolidated Financial Statements:
Purpose and Policy." Under that proposed statement, there would be significant
changes in the way the Company records certain transactions of its controlled
subsidiaries. Among those changes, any sale of the stock of a subsidiary that
does not result in a loss of control would be accounted for in equity of the
consolidated entity with no gain or loss being recorded. The 1995 exposure draft
addressed rule changes concerning consolidation procedures which would affect
the Company's ability to record gains on issuance of subsidiary stock and
consolidation policy, which does not affect the accounting for such gains. The
February 1999 revised exposure draft addresses only consolidation policy. The
FASB has indicated that it will consider resuming discussion on consolidation
procedures after completion of the efforts on consolidation policy. The timing
and content of any final statement on consolidation procedures are uncertain.

      Uncertainty of Growth. Certain of the markets in which the Company
competes have been flat or declining over the past several years. The Company
has pursued a number of potential growth strategies, including acquiring
complementary businesses; developing new applications for its technologies; and
strengthening its presence in selected geographic markets. No assurance can be
given that the Company will be able to successfully implement these strategies,
or that these strategies will result in growth of the Company's business.

      Risks Associated With Acquisition Strategy. One of the Company's growth
strategies is to supplement its internal growth with the acquisition of
businesses and technologies that complement or augment the Company's existing
product lines. Certain businesses acquired by the Company have had low levels of
profitability. In addition, businesses that the Company may seek to acquire in
the future may also be marginally profitable or unprofitable. In order for any
acquired businesses to achieve the level of profitability desired by the
Company, the Company must successfully change operations and improve market
penetration. No assurance can be given that the Company will be successful in
this regard. In addition, promising acquisitions are difficult to identify and
complete for a number of reasons, including competition among prospective
buyers, the need for regulatory approvals, including antitrust approvals, and
the high valuations of businesses resulting from historically high stock prices
in many countries. Acquisitions made by the Company may be made at substantial
premiums over the fair value of the net assets of the acquired companies. There
can be no assurance that the Company will be able to complete pending or future
acquisitions or that the Company will be able to successfully integrate any
acquired business into its existing business or make such businesses profitable.
In order to finance any such acquisitions, it may be necessary for the Company
to raise additional funds either through public or private financing. Any equity
or debt financing, if available at all, may be on terms which are not favorable
to the Company and may result in dilution to the Company's shareholders.

                                       45
<PAGE>

      Risks Associated With Technological Change, Obsolescence, and the
Development and Acceptance of New Products. The market for the Company's
products and services is characterized by rapid and significant technological
change and evolving industry standards. New product introductions responsive to
these factors require significant planning, design, development, and testing at
the technological, product, and manufacturing process levels, and may render
existing products and technologies uncompetitive or obsolete. There can be no
assurance that the Company's products will not become uncompetitive or obsolete.
In addition, industry acceptance of new technologies developed by the Company
may be slow to develop due to, among other things, existing regulations written
specifically for older technologies and general unfamiliarity of users with new
technologies.

      Risks Associated With Dependence on Capital Spending Policies and
Government Funding. The Company's customers include manufacturers of
semiconductors and products incorporating semiconductors, pharmaceutical and
chemical companies, laboratories, government agencies, and public and private
research institutions. The capital spending of these entities can have a
significant effect on the demand for the Company's products. Such spending
levels are based on a wide variety of factors, including the resources available
to make such purchases, the spending priorities among various types of research
equipment, public policy, and the effects of different economic cycles,
including fluctuating demand in the semiconductor industry. Any decrease in
capital spending by any of the customer groups that account for a significant
portion of the Company's sales could have a material adverse effect on the
Company's business and results of operations.

      Possible Adverse Effect From Consolidation in the Environmental Market and
Changes in Environmental Regulations. One of the important markets for the
Company's products is environmental analysis. During the past several years,
there has been a contraction in the market for analytical instruments used for
environmental analysis. This contraction has caused consolidation in the
businesses serving this market. Such consolidation may have an adverse impact on
certain of the Company's businesses. In addition, most air, water, and soil
analysis is conducted to comply with federal, state, local, and foreign
environmental regulations. These regulations are frequently specific as to the
type of technology required for a particular analysis and the level of detection
required for that analysis. The Company develops, configures, and markets its
products to meet customer needs created by existing and anticipated
environmental regulations. These regulations may be amended or eliminated in
response to new scientific evidence or political or economic considerations. Any
significant change in environmental regulations or enforcement efforts could
result in a reduction in demand for the Company's products.

      Risks Associated With the Sale of Products to the Pharmaceutical Industry.
The pharmaceutical industry is one of the important markets for the Company's
products. Although the Company's existing general purpose analytical equipment
and services are not subject to regulation by the U.S. Food and Drug
Administration (the FDA), FDA regulations apply to the processes and production
facilities used to manufacture pharmaceutical products. Any material change by a
pharmaceutical company in its manufacturing process or equipment could
necessitate additional FDA review and approval. Such requirements may make it
more difficult for the Company to sell its products and services to
pharmaceutical customers that have already applied for or obtained approval for
production processes using different equipment and supplies. Any changes in the
regulations that apply to the processes and production facilities used to
manufacture pharmaceutical products may adversely affect the market for the
Company's products. In addition, from time to time as a result of industry
consolidation and other factors, the pharmaceutical industry has reduced its
capital expenditures for equipment such as that manufactured by the Company, and
there can be no assurance that further changes in the pharmaceutical industry
will not adversely affect demand for the Company's products.

                                       46
<PAGE>

      Possible Adverse Impact of Significant International Operations.
International revenues accounted for a significant portion of the Company's
total revenues in 1998, and the Company expects that international revenues will
continue to account for a significant portion of the Company's revenues in the
future. Sales to customers in foreign countries are subject to a number of
risks, including the following: fluctuations in exchange rates may affect
product demand and adversely affect the profitability in U.S. dollars of
products and services provided by the Company in foreign markets where payment
for the Company's products and services is made in the local currency;
agreements may be difficult to enforce and receivables difficult to collect
through a foreign country's legal system; foreign customers may have longer
payment cycles; foreign countries could impose withholding taxes or otherwise
tax the Company's foreign income, impose tariffs, or adopt other restrictions on
foreign trade; export licenses, if required, may be difficult to obtain and the
protection of intellectual property in foreign countries may be more difficult
to enforce. There can be no assurance that any of these factors will not have a
material adverse effect on the Company's business and results of operations. A
portion of the Company's revenues is derived from exports to Asia. Certain
countries in Asia are experiencing a severe economic crisis, which has been
characterized by sharply reduced economic activity and liquidity, highly
volatile foreign-currency-exchange and interest rates, and unstable stock
markets. The Company's export sales to Asia may continue to be adversely
affected by the unstable economic conditions there, which may continue to
adversely affect the Company's results of operations, financial condition, or
business.

      Competition. The Company encounters and expects to continue to encounter
intense competition in the sale of its products. The Company believes that the
principal competitive factors affecting the market for its products include
product performance, price, reliability, and customer service. The Company's
competitors include large multinational corporations and their operating units.
Some of the Company's competitors have substantially greater financial,
marketing, and other resources than those of the Company. As a result, they may
be able to adapt more quickly to new or emerging technologies and changes in
customer requirements, or to devote greater resources to the promotion and sale
of their products, than the Company. In addition, competition could increase if
new companies enter the market or if existing competitors expand their product
lines or intensify efforts within existing product lines. There can be no
assurance that the Company's current products, products under development, or
ability to discover new technologies will be sufficient to enable it to compete
effectively with its competitors.

      Risks Associated With Protection, Defense, and Use of Intellectual
Property. The Company holds many patents relating to various aspects of its
products, and believes that proprietary technical know-how is critical to many
of its products. Proprietary rights relating to the Company's products are
protected from unauthorized use by third parties only to the extent that they
are covered by valid and enforceable patents or are maintained in confidence as
trade secrets. There can be no assurance that patents will issue from any
pending or future patent applications owned by or licensed to the Company or
that the claims allowed under any issued patents will be sufficiently broad to
protect the Company's technology. In the absence of patent protection, the
Company may be vulnerable to competitors who attempt to copy the Company's
products or gain access to its trade secrets and know-how. Proceedings initiated
by the Company to protect its proprietary rights could result in substantial
costs to the Company. There can be no assurance that competitors of the Company
will not initiate litigation to challenge the validity of the Company's patents,
or that they will not use their resources to design comparable products that do
not infringe the Company's patents. There may also be pending or issued patents
held by parties not affiliated with the Company that relate to the Company's
products or technologies. The Company may need to acquire licenses to, or
contest the validity of, any such patents. There can be no assurance that any
license required under any such patent would be made available on acceptable
terms or that the Company would prevail in any such contest. The Company could
incur substantial costs in defending itself in suits brought against it or in
suits in which the Company may assert its patent rights against others. If the
outcome of any such litigation is unfavorable to the Company, the Company's
business and results of operations could be materially adversely affected.
Further, the laws of some jurisdictions do not protect the Company's proprietary
rights to the same

                                       47
<PAGE>

extent as the laws of the U.S. and there can be no assurance that available
protections will be adequate. In addition, the Company relies on trade secrets
and proprietary know-how which it seeks to protect, in part, by confidentiality
agreements with its collaborators, employees, and consultants. There can be no
assurance that these agreements will not be breached, that the Company would
have adequate remedies for any breach, or that the Company's trade secrets will
not otherwise become known or be independently developed by competitors.

      Potential Impact of Year 2000 on Processing of Date-sensitive Information.
While the Company is attempting to minimize any negative consequences arising
from the year 2000 issue, there can be no assurance that year 2000 problems will
not have a material adverse impact on the Company's business, operations, or
financial condition. While the Company expects that upgrades to its internal
business systems will be completed in a timely fashion, there can be no
assurance that the Company will not encounter unexpected costs or delays.
Despite its efforts to ensure that its material current products are year 2000
compliant, the Company may see an increase in warranty and other claims,
especially those related to Company products that incorporate, or operate using,
third-party software or hardware. In addition, certain of the Company's older
products, which it no longer manufactures or sells, may not be year 2000
compliant, which may expose the Company to claims. If any of the Company's
material suppliers or vendors experience business disruptions due to year 2000
issues, the Company might also be materially adversely affected. There is
expected to be a significant amount of litigation relating to the year 2000
issue and there can be no assurance that the Company will not incur material
costs in defending or bringing lawsuits. In addition, if any year 2000 issues
are identified, there can be no assurance that the Company will be able to
retain qualified personnel to remedy such issues. Any unexpected costs or delays
arising from the year 2000 issue could have a significant adverse impact on the
Company's business, operations, and financial condition in amounts that cannot
be reasonably estimated at this time.
</TABLE>


                                       48
<PAGE>
<TABLE>
<CAPTION>
<S>                                             <C>         <C>         <C>          <C>         <C>      

                         Selected Financial Information
                                        
(In thousands except per share amounts)          1998 (a)    1997 (b)     1996 (c)    1995 (d)        1994
- ---------------------------------------------- ----------- ----------- ------------ ----------- -----------

Statement of Income Data
Revenues                                       $1,659,981  $1,592,314   $1,209,362   $ 782,662   $ 649,992
Income From Continuing Operations                 104,084     147,258      132,751      79,306      58,261
Operations
Net Income                                        104,084     147,258      132,751      79,306      60,220
Earnings per Share From Continuing
  Operations:
    Basic                                             .86        1.21         1.12         .70         .53
    Diluted                                           .79        1.09         1.01         .64         .49
Earnings per Share:
    Basic                                             .86        1.21         1.12         .70         .55
    Diluted                                           .79        1.09         1.01         .64         .50

Balance Sheet Data
Working Capital                                 $ 745,955   $ 612,666   $  636,703   $ 489,895   $ 230,306
Total Assets                                    2,565,774   2,351,153    1,924,400   1,372,813   1,011,917
Long-term Obligations                             743,443     673,194      554,214     441,034     263,559
Shareholders' Investment                          945,007     877,558      746,267     542,705     440,763

(a) Reflects a $31.8 million pretax charge, primarily for restructuring costs
    and inventory write-downs, nontaxable gains of $18.6 million from the
    issuance of stock by subsidiaries, and the January 1998 issuance of $250.0
    million principal amount of 4% subordinated convertible debentures due 2005.
(b) Reflects the March 1997 acquisition of Life Sciences International PLC and
    nontaxable gains of $46.4 million from the issuance of stock by
    subsidiaries.
(c) Reflects the March 1996 acquisition of the Fisons businesses, the October
    1996 issuance of $172.5 million principal amount of 4 1/2% senior
    convertible debentures due 2003, and nontaxable gains of $71.7 million from
    the issuance of stock by subsidiaries.
(d) Reflects the August and October 1995 issuance of $96.3 million principal
    amount of 5% subordinated convertible debentures due 2000 by each of
    ThermoQuest and Thermo Optek, respectively, and nontaxable gains of $20.1
    million from the issuance of stock by subsidiaries.






                                       49
<PAGE>
Common Stock Market Information
      The Company's common stock is traded on the American Stock Exchange under
the symbol THI. The following table sets forth the high and low sale prices of
the Company's common stock for 1998 and 1997, as reported in the consolidated
transaction reporting system.

                                                                       1998                    1997
                                                              --------------------   ---------------------
Quarter                                                           High        Low       High         Low
- ------------------------------------------------------------ ---------- ----------  ---------- -----------

First                                                         $35 7/16   $27 13/16    $29 1/5    $23 1/10
Second                                                         34 5/8     25 7/8       28 1/2     22 1/2
Third                                                          26 3/4     11           34 1/5     24 3/5
Fourth                                                         15 1/8     7 7/8        34 1/2     23

      As of January 29, 1999, the Company had 2,653 holders of record of its
common stock. This does not include holdings in street or nominee names. The
closing market price on the American Stock Exchange for the Company's common
stock on January 29, 1999, was $16 5/8 per share.
      Common stock of the Company's majority-owned public subsidiaries is traded
on the American Stock Exchange: ThermoSpectra Corporation (symbol THS),
ThermoQuest Corporation (symbol TMQ), Thermo Optek Corporation (symbol TOC),
Thermo BioAnalysis Corporation (symbol TBA), Metrika Systems Corporation (symbol
MKA), Thermo Vision Corporation (symbol VIZ), and ONIX Systems Inc. (symbol
ONX).

Shareholder Services
      Shareholders of Thermo Instrument Systems Inc. who desire information
about the Company are invited to contact the Investor Relations Department,
Thermo Instrument Systems Inc., 81 Wyman Street, P.O. Box 9046, Waltham,
Massachusetts 02454-9046, (781) 622-1111. A mailing list is maintained to enable
shareholders whose stock is held in street name, and other interested
individuals, to receive quarterly reports, annual reports, and press releases as
quickly as possible. Distribution of printed quarterly reports is limited to the
second quarter only. All material is available from Thermo Electron's Internet
site (http://www.thermo.com/subsid/thi1.html).

Stock Transfer Agent
      American Stock Transfer & Trust Company is the stock transfer agent and
maintains shareholder activity records. The agent will respond to questions on
issuance of stock certificates, change of ownership, lost stock certificates,
and change of address. For these and similar matters, please direct inquiries
to:

      American Stock Transfer & Trust Company
      Shareholder Services Department
      40 Wall Street, 46th Floor
      New York, New York 10005
      (718) 921-8200

Dividend Policy
      The Company has never paid cash dividends and does not expect to pay cash
dividends in the foreseeable future because its policy has been to use earnings
to finance expansion and growth. Payment of dividends will rest within the
discretion of the Board of Directors and will depend upon, among other factors,
the Company's earnings, capital requirements, and financial condition.

                                       50
<PAGE>

Form 10-K Report
      A copy of the Annual Report on Form 10-K for the fiscal year ended January
2, 1999, as filed with the Securities and Exchange Commission, may be obtained
at no charge by writing to the Investor Relations Department, Thermo Instrument
Systems Inc., 81 Wyman Street, P.O. Box 9046, Waltham, Massachusetts 02454-9046.

Annual Meeting
      The annual meeting of shareholders will be held on Thursday, May 27, 1999,
at 11 a.m., at The Westin Hotel, 70 Third Avenue, Waltham, Massachusetts.
</TABLE>

                                       51
<PAGE>

<TABLE>
<CAPTION>
                                                                                              Exhibit 21
                         THERMO INSTRUMENT SYSTEMS INC.

                         Subsidiaries of the Registrant

<S>                                                                  <C>                  <C>

      At February 28, 1999, the Registrant owned the following companies:

                                                                          STATE OR         REGISTRANT'S
                                                                      JURISDICTION OF       PERCENT OF
                               NAME                                    INCORPORATION         OWNERSHIP
- ----------------------------------------------------------------------------------------------------------

    Thermo Instrument Systems Inc.                                        Delaware            85.40**
        Analytical Instrument Development, Inc.                         Pennsylvania            100
        Eberline Instrument Company Limited                            United Kingdom           100
        Eberline Instrument Corporation                                  New Mexico             100
        Epsilon Industrial Inc.                                            Texas                100
        ESM Eberline Instruments Strahlen - und Umweltmesstechnik         Germany               100
        GmbH
        Fisons Instruments Vertriebs GmbH                                 Germany               100
        Gas Tech Inc.                                                    California             100
           Gas Tech Australia, Pty. Ltd.                                 Australia              50*
           Gas Tech Partnership                                          California             50*
           Gastech Instruments Canada Ltd.                                 Canada               100
        Life Sciences International Limited                            United Kingdom           100
           Comdata Services Limited                                       England               100
               Lipshaw Limited                                            England               100
               Luckham Limited                                            England               100
               Phicom Limited                                             England               100
               Shandon Scientific Limited                                 England               100
               Southions Investments Limited                              England               100
               Sungei Puntar Rubber Estate Limited                        England               100
               Westions Limited                                           England               100
               Whale Scientific Limited                                   England               100
           Helmet Securities Limited                                      England               100
               Life Sciences International GmbH                           Germany               100
               Life Sciences International Kft                            Hungary               100
               Life Sciences International, Inc.                        Pennsylvania            100
                  LSI (US) Inc.                                           Delaware              100
               LSI North America Service Inc.                             Delaware              100
               Life Sciences International Holdings BV                  Netherlands             100
                  Life Sciences International (Poland) SP z O.O            Poland               100
           Angila Scientific Instruments Limited                          England               100
           Britlowes Limited                                              England               100
           Commendstar Limited                                            England               100
           Consumer & Video Holdings Limited                              England               100
               Video Communications Limited                               England               100
           Greensecure Projects Limited                                   England               100
           Labsystems Europe GA                                            Spain                100
           Labsystems Ges mbH                                             Austria               100
           Omnigene Limited                                               England              58.50
           Shandon Southern Instruments Limited                           England               100
           Shenbridge Limited                                             England               100
           Southern Instruments Holdings Limited                          England               100



<PAGE>

        Metrika Systems Corporation                                        Delaware            67.49**
        (additionally, 8.11%** of the shares are owned
        directly by The Thermo Electron Companies Inc.)
           Radiometrie RM GmbH                                             Germany               100
           Eberline Radiometrie S.A.                                        France               100
           Gamma-Metrics                                                  California             100
           MF Physics Corporation                                          Delaware              100
           Radiometrie Corporation                                         Delaware              100
               DMC Mess & Regeltechnik GmbH                                Germany               100
           Radiometrie U.S.A., Inc.                                       California             100
           Radiometrie Limited                                          United Kingdom               100
        National Nuclear Corporation                                      California             100
           Thermo Nucleonics LLC                                           Delaware              51
           (additionally, 49% of the shares are owned
           directly by TBA Nucleonics Holding Corporation)
        ONIX Systems Inc.                                                  Delaware            80.31**
        (additionally, 0.73% of the shares are owned
        directly by The Thermo Electron Companies Inc.)
           Brandt Instruments, Inc.                                        Delaware              100
           CAC Inc.                                                        Delaware              100
               Flow Automation Inc.                                         Texas                100
               Lots 82 and 83, Inc.                                       Louisiana              100
               Mid-South Power Systems, Inc.                              Louisiana              100
               Mid-South Controls & Services, Inc.                        Louisiana              100
               Thermo Instrument Controls de Mexico, S.A. de C.V.           Mexico               100
               (1% of which shares are owned directly
               by ONIX Systems Inc.)
           ONIX Process Analysis Inc.                                       Texas                100
           OnIX Holdings Limited                                           England               100
               CAC UK Limited                                         England and Wales          100
               ONIX Measurement Limited                               England and Wales          100
                  Peek Environmental Limited                          England and Wales          100
                  Sarasota Data Products Limited                      England and Wales          100
                  Sarasota Instrumentation Limited                    England and Wales          100
               VG Gas Analysis Limited                                England and Wales          100
           Polysonics, Inc.                                                 Texas                100
           TN Spectrace Europe B.V.                                      Netherlands             100
           TN Technologies Inc.                                             Texas                100
               Kay-Ray/Sensall, Inc.                                       Delaware              100
               TN Technologies Canada Inc.                                  Canada               100
           Westronics Inc.                                                  Texas                100
        Optek-Nicolet Holdings Inc.                                       Wisconsin              100
           Thermo Optek Corporation                                        Delaware            92.70**
           (additionally, 2.01%** of the shares are owned
           directly by The Thermo Electron Companies Inc.)
               Diametrix Detectors, Inc.                                   Delaware              100
               FI Instruments Inc.                                         Delaware              100
               Gebrueder Haake GmbH                                        Germany               100

                                                2
<PAGE>


                  RHEO S.A.                                                 France               100
                  SWO Polymertechnik GmbH                                  Germany               100
               HB Instruments Inc.                                         Delaware              100
               Scintag, Inc.                                              California             100
               Spectronic Instruments, Inc.                                Delaware              100
                  SLM International Inc.                                   Illinois              100
               Thermo Jarrell Ash Corporation                           Massachusetts            100
                  A.R.L. Applied Research Laboratories S.A.              Switzerland             100
                      Fisons Instruments (Proprietary) Limited           South Africa            100
                      Thermo Optek Wissenschaftliche Gerate GesmbH         Austria               100
                  Baird De Brazil Representacoes Ltda.                      Brazil               100
                  Beijing Baird Analytical Instrument Technology            China                100
                  Co. Limited
               Cahn Instrument Corporation                                Wisconsin              100
                  Mattson Instruments Limited                           United Kingdom           100
                  Thermo Optek Limited                                  United Kingdom           100
                      Norlab Instrument of Aberdeen (UK)                United Kingdom           100
                      Thermo Elemental Limited                          United Kingdom           100
                      Unicam Limited                                    United Kingdom           100
                          Unicam Export Limited                         United Kingdom           100
                  Unicam Analytical Technology Netherlands B.V.          Netherlands             100
                  Unicam Italia SpA                                         Italy                100
                  Unicam S.A.                                              Belgium               100
               Thermo Optek Nordic AB                                       Sweden               100
               Nicolet Instrument Corporation                             Wisconsin              100
                  Nicolet Japan K.K.                                        Japan                100
                  Spectra-Tech, Inc.                                      Wisconsin              100
                  Spectra-Tech, Europe Limited                          United Kingdom           100
               Nicolet Instrument GmbH                                     Germany               100
               Optek Securities Corporation                             Massachusetts            100
               Planweld Holding Limited                                 United Kingdom           100
                  Nicolet Instrument Limited                            United Kingdom           100
                      Hilger Analytical Limited                         United Kingdom           100
                  Thermo Electron Limited                               United Kingdom           100
               Thermo Instrument Systems Japan Holdings, Inc.              Delaware              100
                  Nippon Jarrell-Ash Company, Ltd.                          Japan                100
               Thermo Instruments (Canada) Inc.                             Canada               100
                  Fisons Instruments Inc.                                   Canada               100
                  Unicam Analytical Inc.                                    Canada               100
               Thermo Optek France S.A.                                     France               100
               Thermo Optek Holding B.V.                                 Netherlands             100
                  Baird Europe B.V.                                      Netherlands             100
                      Baird France S.A.R.L.                                 France               100
               VG Systems Limited                                       United Kingdom           100
               VG Elemental Limited                                     United Kingdom           100
               Thermo Group B.V.                                         Netherlands             100
               Thermo Optek Materials Analysis (S.E.A.) Pte Limited       Singapore              100

                                       3
<PAGE>


           ThermoSpectra Corporation                                       Delaware            82.45**
           (additionally, 9.73%** of the shares are owned
           directly by The Thermo Electron Companies Inc.)
               Gould Instrument Systems, Inc.                                Ohio                100
               Kevex Instruments Inc.                                      Delaware              100
               Kevex X-Ray Inc.                                            Delaware              100
               Neslab Instruments Europa BV                              Netherlands             100
               Neslab Instruments, Inc.                                 New Hampshire            100
               Neslab Instruments Limited                                  England               100
               Nicolet Instrument Technologies Inc.                       Wisconsin              100
               NORAN Instruments Inc.                                     Wisconsin              100
               ThermoMicroscopes Corp.                                    California             100
                  ThermoMicroscopes S.A.                                 Switzerland             100
                  PSI Virgin Islands Incorporated                    U.S. Virgin Islands         100
               Sierra Research and Technology, Inc.                        Delaware              100
               ThermoSpectra  B.V.                                       Netherlands             100
                  Nicolet Technologies B.V.                              Netherlands             100
                      Bakker Electronics Limited                        United Kingdom           100
                  NORAN Instruments B.V.                                 Netherlands             100
               ThermoSpectra GmbH                                          Germany               100
                  Gould Nicolet Messtechnik GmbH                           Germany               100
                      NORAN Instruments GmbH                               Germany               100
                  ThermoMicroscopes GmbH                                   Germany               100
               ThermoSpectra Limited                                    United Kingdom           100
                  Nicolet Technologies Ltd.                             United Kingdom           100
               ThermoSpectra S.A.                                           France               100
                  Nicolet Technologies S.A.R.L.                             France               100
        Spectrace Instruments Inc.                                        California             100
        TMO THI Acquisition Corp.                                          Delaware              100
        Thermo Electron Sweden Forvaltning AB                               Sweden               100
        Quest-Finnigan Holdings Inc.                                       Virginia              100
        Quest-TSP Holdings Inc.                                            Delaware              100
           ThermoQuest Corporation                                         Delaware            89.31**
           (43.9%** of which shares are owned directly by
           Quest-Finnigan Holdings Inc.) (additionally, 0.31% of
           the shares are owned directly by The Thermo Electron
           Companies Inc.)
               Denley Instruments Limited                                  England               100
               E-C Apparatus Limited                                       England               100
               Finnigan FT/MS Inc.                                         Delaware              100
               Finnigan Corporation                                        Delaware              100
                  Finnigan Instruments, Inc.                               New York              100
                  Finnigan International Sales, Inc.                      California             100
                  Finnigan MAT China, Inc.                                California             100
                  Finnigan MAT (Delaware), Inc.                            Delaware              100
                  Finnigan MAT Instruments, Inc.                            Nevada               100
                  Finnigan MAT International Sales, Inc.                  California             100
                  Finnigan MAT (Nevada), Inc.                               Nevada               100
                      Finnigan MAT GmbH                                    Germany               100


                                       4
<PAGE>

                          ThermoQuest Analytische Systeme GmbH             Germany               100
                      Finnigan MAT S.R.L.                                   Italy                100
                          Thermo Separation Products S.R.L.                 Italy                100
                      Masslab Limited                                   United Kingdom           100
                      Thermo Instruments Australia Pty. Limited           Australia              100
                      ThermoQuest Ltd.                                  United Kingdom           100
                          Finnigan MAT Ltd.                             United Kingdom           100
                             ThermoQuest AB                                 Sweden               100
                          Thermo Separation Products Ltd.               United Kingdom           100
                  Finnigan Properties, Inc.                               California             100
               Forma Scientific, Inc.                                      Delaware              100
                  Forma Ohio Inc.                                            Ohio                100
                  International Equipment Company                          Delaware              100
                      International Equipment Company Limited              England               100
                  Savant Instruments, Inc.                                 New York              100
               Forma Scientific Limited                                    England               100
               Hypersil Inc.                                               Delaware              100
               Hypersil Limited                                            England               100
               Life Sciences International (Hong Kong) Limited            Hong Kong              100
               Life Sciences International, Inc.                         Pennsylvania            100
               Life Sciences (Europe) Limited                              England               100
                  Life Sciences International (UK) Limited                 England               100
                      Kenbury Limited                                      England               100
               Savant Instruments Limited                                  England               100
               ThermoQuest B.V.                                          Netherlands             100
                  Thermo Separation Products B.V.                        Netherlands             100
                      Thermo Separation Products B.V. B.A.                 Belgium               100
               ThermoQuest France S.A.                                      France               100
                  Finnigan Automass S.A.                                    France               100
                  Finnigan MAT S.A.R.L.                                     France               100
                  Thermo Separation Products S.A.                           France               100
               ThermoQuest Italia S.p.A.                                    Italy                100
               ThermoQuest Spain S.A.                                       Spain                100
               ThermoQuest Wissenschaftliche Gerate GmbH                   Austria               100
               Thermo Separation Products AG                             Switzerland             100
               Thermo Separation Products Inc.                             Delaware              100
               ThermoQuest K.K.                                             Japan                100
        RealFlex Systems Inc.                                               Texas                100
        SID Instruments Inc.                                               Delaware              100
           FI S.A.                                                          France               100
           Fisons Instruments BV                                         Netherlands             100
           Fisons Instruments NV                                           Belgium               100
           Fisons Instruments K.K.                                          Japan                100
           NK Instruments Inc.                                             Delaware              100
           Thermo Capillary Electrophoresis Inc.                           Delaware              100
           Thermo Haake Ltd.                                            United Kingdom           100
           Thermo Haake (U.K.) Limited                                  United Kingdom           100
           Thermo Instrumentos Cientificos S.A.                             Spain                100
        Tera Systemes

                                       5
<PAGE>


        Thermo BioAnalysis Corporation                                      Delaware           61.98**
        (4.1%** of which shares are owned directly by
        Quest-TSP Holdings Inc. and 1.8% of which shares
        are owned directly by Quest-Finnigan Holdings Inc.
        Additionally, 21.75%** of the shares are owned directly by
        The Thermo Electron Companies Inc.)
           BioStar, Inc.                                                    Delaware             100
           Data Medical Associates, Inc.                                     Texas               100
               DMA Latinoamerica S.A. de C.V.                                Mexico              50
           Denley Instruments Inc.                                       North Carolina          100
           Fastighets AB Skrubba                                             Sweden              100
           Dynex Technologies spol. s.r.o.                               Czech Republic          100
           DYNEX Technologies (Asia) Inc.                                   Delaware             100
           DYNEX Technologies Inc.                                          Virginia             100
               DYNEX Technologies GmbH                                      Germany              100
           Hybaid Limited                                                   England              100
               Hybaid BV                                                  Netherlands            100
           Thermo Labsystems B.V.                                         Netherlands            100
           Labsystems Inc.                                                  Delaware             100
           Thermo BioAnalysis Japan K.K.                                     Japan               100
           Labsystems OY                                                    Finland              100
               Biosystems OY                                                Finland              100
               Labsystems (Hong Kong) Limited                              Hong Kong             99
               Life Sciences International (Hong Kong) Limited             Hong Kong             99
               Labsystems BTD                                                China              32.50
               Labsystems LHD                                                China               100
               Labsystems Lenpipette                                         Russia              95
               Labsystems Pakistan (Private) Ltd                            Pakistan            33.50
           Labsystems Sweden AB                                              Sweden              100
           Labsystems (UK) Limited                                          England              100
           Life Sciences International SNC                                   France              100
               Shandon SA                                                    France              100
               Shandon (France) SA                                           France              100
           Shandon Scientific Limited                                    United Kingdom          100
               Anglia Scientific Instruments Limited                     United Kingdom          100
               Shandon Southern Instruments Limited                      United Kingdom          100
               Life Sciences International (Benelux) B.V.                 Netherlands            100
           Shandon Inc.                                                   Pennsylvania           100
               E-C Apparatus Corporation                                    Florida              100
               Whale Scientific Corporation                                 Colorado             100
               ALKO Diagnostic Corporation                               Massachusetts           100
           TBA Nucleonics Holding Corporation                               Delaware             100
             Thermo Nucleonics LLC                                          Delaware             49
           TBA Securities Corporation                                    Massachusetts           100
           Shandon GmbH                                                     Germany              100
           Thermo BioAnalysis GmbH                                          Germany              100


                                       6
<PAGE>

               Hybaid GmbH                                                  Germany              100
                  Angewandte Gentechnologie Systems GmbH                    Germany              100
               Labsystems GmbH                                              Germany              100
               Thermo LabSystems Vertriebs GmbH                             Germany              100
           Thermo BioAnalysis (Guernsey) Ltd.                           Channel Islands          100
           Thermo BioAnalysis Holdings, Limited                          United Kingdom          100
               Thermo Fast U.K. Limited                                  United Kingdom          100
               Dynex Technologies Limited                                United Kingdom          100
               Thermo BioAnalysis Limited                                United Kingdom          100
               Thermo LabSystems Limited                                 United Kingdom          100
           Thermo BioAnalysis S.A.                                           France              100
               Thermo LabSystems S.A.R.L.                                    France              100
               Labsystems S.A.R.L.                                           France              100
           Thermo LabSystems (Australia) Pty Limited                       Australia             100
           Thermo LabSystems Inc.                                        Massachusetts           100
           BioAnalysis LabSystems, S.A.                                      Spain               100
           Trace Scientific Limited                                        Australia             100
               Trace BioSciences Ltd.                                      Australia             100
               Trace BioSciences NZ Limited                               New Zealand            99
               Trace America, Inc.                                          Florida              100
               Herbos Dijaganosticka                                        Croatia              50
               Shanghai Long March Chiron Trace Medical Science Co.               China          22
               Ltd.
        Thermo Environmental Instruments Inc.                              California            100
           Andersen Instruments Inc.                                        Delaware             100
               Andersen Instruments Limited                              United Kingdom          100
           MIE Corporation                                               Massachusetts           100
        Thermo Instruments do Brasil Ltda.                                   Brazil              100
        (1% of which shares are owned directly
        by Thermo Jarrell Ash Corporation)
        Van Hengel Holding B.V.                                           Netherlands            100
           Thermo Instrument Systems B.V.                                 Netherlands            100
               Euroglas B.V.                                              Netherlands            100
               Mesure de Traces                                           Netherlands            100
               ThIS Automation B.V.                                       Netherlands            100
               This Analytical B.V.                                       Netherlands            100
               This Gas Analysis B.V.                                     Netherlands
               This Lab Systems B.V.                                      Netherlands            100
               This Scientific B.V.                                       Netherlands            100
           Thermo Instruments GmbH                                          Germany              100
           Thermo Jarrell Ash, S.A.                                          Spain               100
        Thermo Vision Corporation                                           Delaware           78.27**
        (additionally, 1.27%** of the shares are owned
        directly by The Thermo Electron Companies Inc.)
           CID Technologies Inc.                                            New York             100
           Centro Vision Inc.                                               Delaware             100
           Hilger Crystals Limited                                       United Kingdom          100
           Laser Science, Inc.                                              Delaware             100
           Oriel Instruments Corporation                                    Delaware             100
           Thermo Vision Opticon Corporation                                Delaware             100

* Joint Venture/Partnership                         ** As of January 2, 1999

</TABLE>


                                                                      Exhibit 23

                    Consent of Independent Public Accountants

     As independent public  accountants,  we hereby consent to the incorporation
by reference of our reports dated  February 16, 1999 (except with respect to the
matter discussed in Note 18, as to which the date is March 1, 1999), included in
or incorporated by reference into Thermo Instrument Systems Inc.'s Annual Report
on Form 10-K for the year ended January 2, 1999,  into the Company's  previously
filed Registration Statements as follows: Registration Statement No. 33-14980 on
Form  S-8,  Registration  Statement  No.  33-16461  on  Form  S-8,  Registration
Statement No.  33-14974 on Form S-8, Post  Effective  Amendment to  Registration
Statement on Form S-4 No.  33-32579-02 on Form S-8,  Registration  Statement No.
33-33577  on  Form  S-8,  Registration  Statement  No.  33-36221  on  Form  S-8,
Registration  Statement  No.  33-37866 on Form S-8,  Registration  Statement No.
33-42270  on  Form  S-3,  Registration  Statement  No.  33-69526  on  Form  S-3,
Registration  Statement  No.  33-65275 on Form S-8,  Registration  Statement No.
33-37559 on Form S-8,  Registration  Statement  No.  333-02163  on Form S-3, and
Registration Statement No. 333-17707 on Form S-3.


                                                           Arthur Andersen LLP



Boston, Massachusetts
March 18, 1999



<TABLE> <S> <C>

<ARTICLE>           5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THERMO
INSTRUMENT SYSTEMS INC.'S ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED JANUARY
2, 1999 AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL
STATEMENTS.
</LEGEND>
<MULTIPLIER>        1,000
       
<S>                              <C>
<PERIOD-TYPE>                                 YEAR
<FISCAL-YEAR-END>                             JAN-02-1999
<PERIOD-END>                                  JAN-02-1999
<CASH>                                                553,825
<SECURITIES>                                                0
<RECEIVABLES>                                         431,156
<ALLOWANCES>                                           23,726
<INVENTORY>                                           276,589
<CURRENT-ASSETS>                                    1,333,584
<PP&E>                                                344,368
<DEPRECIATION>                                        124,137
<TOTAL-ASSETS>                                      2,565,774
<CURRENT-LIABILITIES>                                 587,629
<BONDS>                                               599,643
                                       0
                                                 0
<COMMON>                                               12,288
<OTHER-SE>                                            932,719
<TOTAL-LIABILITY-AND-EQUITY>                        2,565,774
<SALES>                                             1,659,981
<TOTAL-REVENUES>                                    1,659,981
<CGS>                                                 889,575
<TOTAL-COSTS>                                         889,575
<OTHER-EXPENSES>                                      113,917
<LOSS-PROVISION>                                        4,169
<INTEREST-EXPENSE>                                     45,458
<INCOME-PRETAX>                                       193,916
<INCOME-TAX>                                           74,674
<INCOME-CONTINUING>                                   103,565
<DISCONTINUED>                                              0
<EXTRAORDINARY>                                           519
<CHANGES>                                                   0
<NET-INCOME>                                          104,084
<EPS-PRIMARY>                                            0.86
<EPS-DILUTED>                                            0.79
        

</TABLE>


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