SMITH BARNEY NATURAL RESOURCES FUND INC
N-30D, 2001-01-04
Previous: DREYFUS DEBT & EQUITY FUNDS, 497J, 2001-01-04
Next: SOUTH FINANCIAL GROUP INC, S-8, 2001-01-04




--------------------------------------------------------------------------------
                                 SMITH BARNEY
                               SECTOR SERIES INC.
                             FINANCIAL SERVICES FUND
--------------------------------------------------------------------------------

               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000






                                 [LOGO OMITTED]
                                  Smith Barney
                                  Mutual Funds
                 Your Serious Money. Professionally Managed(SM)

--------------------------------------------------------------------------------
             NOT FDIC INSURED o NOT BANK GUARANTEED o MAY LOSE VALUE
--------------------------------------------------------------------------------

<PAGE>

                                                       [Graphic] Research Series

ANNUAL REPORT o OCTOBER 31, 2000

SMITH BARNEY FINANCIAL
SERVICES FUND

CITIBANK GLOBAL ASSET
MANAGEMENT

Citibank, N.A., through its Citibank Global Asset Management division, is the
subadviser to the Fund. Comprised of a seasoned group of investment and research
professionals, the Fund's management team follows a systematic and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks long-term capital appreciation by investing primarily in common
stocks. The Fund invests at least 80% of its assets in securities of companies
principally engaged in providing financial services to consumers and industry.
These companies may include, for example, commercial banks, savings and loan
associations, broker-dealers, investment banks, investment advisers, insurance
companies, real estate-related companies, leasing companies, and consumer and
industrial finance companies.

FUND FACTS

FUND INCEPTION
--------------------------------------------------------------------------------
February 28, 2000

            CLASS A    CLASS B    CLASS L
--------------------------------------------------------------------------------
NASDAQ      N/A        SBFBX      SFSLX
--------------------------------------------------------------------------------
Inception   2/28/00    2/28/00    2/28/00
--------------------------------------------------------------------------------


SMITH BARNEY FINANCIAL SERVICES FUND*
AVERAGE ANNUAL TOTAL RETURNS AS OF OCTOBER 31, 2000

                                WITHOUT SALES CHARGES(1)

                               Class A    Class B     Class L
--------------------------------------------------------------------------------
Since Inception
(February 28, 2000)**           39.39%     38.68%     38.68%
--------------------------------------------------------------------------------

                          WITH SALES CHARGES(2)

                               Class A    Class B    Class L
--------------------------------------------------------------------------------
Since Inception
(February 28, 2000)**           32.42%     33.68%     36.30%
--------------------------------------------------------------------------------

*    Since the Fund focuses its investments on companies involved in financial
     services, an investment in the fund may involve a greater degree of risk
     than an investment in other mutual funds with greater diversification.

**   Not Annualized.

(1)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value and does not reflect deduction of all applicable
     sales charges with respect to Class A and L shares or the applicable
     contingent deferred sales charges ("CDSC") with respect to Class B and L
     shares.

(2)  Assumes reinvestment of all dividends and capital gain distributions, if
     any at net asset value. In addition, Class A and L shares reflect the
     deduction of the maximum sales charge of 5.00% and 1.00%, respectively; and
     Class B shares reflect the deduction of a 5.00% CDSC, which applies if
     shares are redeemed within one year from initial purchase. Thereafter, this
     CDSC declines by 1.00% per year until no CDSC is incurred. Class L shares
     also reflect the deduction of a 1.00% per year until no CDSC is incurred.
     Class L shares also reflect the deduction of 1.00% CDSC, which applies if
     shares are redeemed within the first year of purchase.

--------------------------------------------------------------------------------

WHAT'S INSIDE

Your Investment in the Smith Barney

Financial Services Fund ............................   1
A Letter from the Chairman .........................   2
Fund at a Glance ...................................   3
Shareholder Letter .................................   4
Schedule of Investments ............................   8
Statement of Assets and Liabilities ................  11
Statement of Operations ............................  12
Statement of Changes in Net Assets .................  13
Notes to Financial Statements ......................  14
Financial Highlights ...............................  17
Independent Auditors` Report .......................  20


                                 [LOGO OMITTED]
                                  Smith Barney
                                  Mutual Funds
                 Your Serious Money. Professionally Managed(SM)

--------------------------------------------------------------------------------
  Investment Products: Not FDIC Insured o Not Bank Guaranteed o May Lose Value
--------------------------------------------------------------------------------
<PAGE>

--------------------------------------------------------------------------------
           YOUR INVESTMENT IN THE SMITH BARNEY FINANCIAL SERVICES FUND
--------------------------------------------------------------------------------

Led by Citibank  N.A.  through its  Citibank  Global Asset  Management  ("CGAM")
division,  the Fund offers  investors  the  opportunity  to  participate  in the
long-term  growth  potential  of the  financial  services  industry.  The Fund's
management  team is comprised  of a seasoned  group of  investment  and research
professionals  who follow a systematic and rigorous approach designed to provide
appropriate exposure to each market sector.



[GRAPHIC]      FINANCIAL SERVICES--A DYNAMIC MARKET SECTOR

               Changing demographic trends--coupled with recent economic growth
               in the U.S.--has led to higher demand for financial services.
               This increased demand, combined with industry consolidation,
               evolving distribution channels and industry deregulation, may
               offer exciting investment opportunities in financial services.

[GRAPHIC]      DIVERSIFICATION IN A TARGETED SECTOR*

               An investment in the Fund offers investors a way to invest in the
               broad range of financial service companies both in the U.S. and
               abroad. The Fund's investments may include companies in a wide
               range of industries such as commercial banks, real estate and
               insurance among others.

[GRAPHIC]      THE BENEFITS OF EXHAUSTIVE FUNDAMENTAL SECURITIES ANALYSIS--
               THE RESEARCH SERIES

               The Research Series is a selection of Smith Barney Mutual Funds
               built on a foundation of substantial buy-side research under the
               direction of Citibank Global Asset Management. This series of
               funds focus on well-defined industries, sectors and trends.

[GRAPHIC]      A COMMITMENT TO MANAGING YOUR SERIOUS MONEY

               SSB Citi Asset Management Group ("SSB Citi"), the investment
               management division of Citigroup comprises Smith Barney Asset
               Management, Salomon Brothers Asset Management and Citibank Global
               Asset Management, each an organization with extensive investment
               capabilities.

               SSB Citi, as a member of one of the largest financial services
               providers in the world, offers you the benefits of our global
               capabilities. At SSB Citi, you gain access to portfolio
               management delivered professionally. We are proud to offer you,
               the serious investor, a variety of managed solutions.

*Please note that because the Fund invests in a single  industry,  its shares do
not  represent  a complete  investment  program  and the value of its shares may
fluctuate more than shares invested in a broader range of industries.



   1 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
                           A LETTER FROM THE CHAIRMAN
--------------------------------------------------------------------------------

[PHOTO]

HEATH B. MCLENDON
CHAIRMAN

The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks may be running  out of steam.  At SSB Citi Asset
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.

We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their businesses. Today, with over $398.6 billion in assets under management,(1)
SSB Citi offers  choices and  solutions,  uniting the  distinguished  history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.

A FEW THOUGHTS ON SECTOR INVESTING

Over the past few years,  we have seen how profoundly the  advancements  made in
sectors such as technology and  telecommunications  have  transformed  our daily
lives.  Computer  applications,  wireless  communications  and  biotechnological
discoveries have created new investment  opportunities and have also transformed
the financial services  industry.  The new and developing sectors of the economy
that are involved in bringing these products,  services and technologies to life
may offer  exceptional  growth  potential,  and many investors  should  consider
having a portion of their investment portfolios in them.

Although most of us recognize that certain sectors drive the economy, we believe
it is much more  difficult  to  determine  which  companies  within a particular
sector,  such as financial  services,  will perform  better than the others over
time.  The  team  of  experienced  professionals  at  Citibank  N.A.  thoroughly
researches  a broad  range of  companies  within a given  sector  and  carefully
analyzes them,  looking to identify those  companies that they believe offer the
greatest  growth  potential  over the long term.  Through  this  exhaustive  and
proprietary  process,  CGAM seeks to offer you an  opportunity to participate in
those  companies  that it  believes  are  best-positioned  in  their  respective
industries.

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.

When you  invest  with SSB  Citi,  you can do so with the  confidence  that your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.

Thank you for your confidence in our investment management approach.

Sincerely,



/s/ Heath B. McLendon
------------------------

Heath B. McLendon
Chairman


November 6, 2000


-----------
(1) AS OF OCTOBER 31, 2000. THIS FIGURE REPRESENTS RETAIL, INSTITUTIONAL, MONEY
    AND SEPARATE ACCOUNTS.



   2 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY FINANCIAL SERVICES FUND AT A GLANCE (UNAUDITED)
--------------------------------------------------------------------------------

GROWTH OF $10,000 INVESTED IN THE
SMITH BARNEY FINANCIAL SERVICES FUND VS. GOLDMAN SACHS FINANCIALS INDEX
--------------------------------------------------------------------------------

       [The following table represents a line chart in the printed piece.]

       FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) -- OCTOBER 31, 2000

                                     Class A          GOLDMAN
                     2/28/00             9500           10000
                     2/29/00          9516.67           10000
                     3/31/00          11108.3           11759
                     4/28/00            10725         11348.6
                     5/31/00          11358.3         11992.1
                     6/30/00          10741.7         11330.1
                     7/31/00          11641.7         12353.2
                     8/31/00          12758.3         13545.3
                     9/30/00          13266.7         14005.8
                     10/31/00         13241.7         13914.8

A $10,000  investment  in the Fund made on February 28, 2000 would have grown to
$13,242 with sales charge (as of October 31, 2000). The graph shows how the Fund
compares to its  benchmark for the same period.  The graph  includes the initial
sales charge on the Fund (no comparable charge exists for the index) and assumes
all dividends and distributions are reinvested at Net Asset Value.

* The Goldman  Sachs  Financials  Index is comprised of companies in the banking
  services,  brokerage, asset management,  insurance and real estate industries.
  Please note that an investor cannot invest directly in an index.


--------------------------------------------------------------------------------
                         TOP TEN COMMON STOCK HOLDINGS*
--------------------------------------------------------------------------------

 1. AMERICAN INTERNATIONAL GROUP ...................   4.9%

 2. WELLS FARGO & CO. ..............................   4.8

 3. BANK AMERICA CORP. .............................   4.2

 4. BERKSHIRE HATHAWAY INC. ........................   4.1

 5. AMERICAN EXPRESS CO. ...........................   4.0

 6. FEDERAL NATIONAL MORTGAGE ASSOCIATION ..........   3.7

 7. MORGAN STANLEY DEAN WITTER .....................   3.6

 8. FEDERAL HOME LOAN MORTGAGE CORP. ...............   2.8

 9. CHASE MANHATTAN CORP. ..........................   2.6

10. MERRILL LYNCH & CO. INC. .......................   2.4

* As a percentage of total investments.



--------------------------------------------------------------------------------
                              PORTFOLIO BREAKDOWN*
--------------------------------------------------------------------------------

       [The following table represents a pie chart in the printed piece.]

 1.1% Consumer Services
 0.7% Discount Note
 2.1% Savings & Loans
 2.6% Real Estate
13.9% Brokers & Investment Managers
17.0% Financials Companies & Services
25.5% Insurance
37.1% Banks



   3 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

DEAR SHAREHOLDER,

We are pleased to provide the annual  report for the Smith Barney  Sector Series
Inc.--Smith Barney Financial Services Fund ("Fund") for the period from February
28,  2000  through  October 31,  2000.  In this  report we have  summarized  the
period's  prevailing  economic and market conditions and outlined our investment
strategy.  The information provided in this letter represents the opinion of the
manager and is not  intended to be a forecast of future  events,  a guarantee of
future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 10 for a complete list and percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE AND FINANCIAL SERVICES SECTOR UPDATE

Since the Fund's  inception on February 28, 2000 through  October 31, 2000,  the
Fund's  Class A,  shares,  without and with sales  charges  returned  39.39% and
32.42%,  respectively.  In  comparison,  the Goldman Sachs  Financials  Index(1)
returned 39.15% for the same time period.  Past performance is not indicative of
future results.

SECTOR INVESTING--THE CGAM PROCESS

Our  approach  to  sector  investing  is based on  exhaustive  research  that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive industry expertise.  Our team looks for analytical consistency through
intensive modeling and strict application of a consistent valuation methodology.

Our management team is made up of a group of high-quality,  seasoned, investment
and  research  professionals  who  follow a  systematic  and  rigorous  strategy
designed  to  provide  the right  exposure  to  various  industries  within  any
particular sector they cover. Our exhaustive  fundamental  research  evaluates a
universe of businesses in our global quest to identify and  participate  in what
we deem attractive investment opportunities.

                          A THREE-STEP RESEARCH PROCESS
              -----------         ------------        ----------------
              FUNDAMENTAL  ----   QUANTITATIVE  ----  ACTIVE PORTFOLIO
              RESEARCH            RESEARCH            MANAGEMENT
              -----------         ------------        ----------------

We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to  create  portfolios  that we think  should  generate  competitive
returns while helping to moderate risk over time.

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)

Our  fundamental,  proprietary  research  can  add  value  to  active  portfolio
management by providing timely and unbiased information to their decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

o Superior products or services

o Outstanding managements


----------
(1) THE GOLDMAN SACHS  FINANCIALS INDEX IS COMPRISED OF COMPANIES IN THE BANKING
    SERVICES, BROKERAGE, ASSET MANAGEMENT, INSURANCE AND REAL ESTATE INDUSTRIES.
    PLEASE NOTE THAT AN INVESTOR CANNOT INVEST DIRECTLY IN AN INDEX.

   4 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

o Solid balance sheets

o Market leadership

o Leading innovation

In our opinion,  these are the companies'  strengths that can potentially create
real value and lead to strong earnings and sales growth, which ultimately drives
stock prices.

--------------------------------------------------------------------------------
 WHILE THE NUMBER OF U.S. BANKING ORGANIZATIONS FELL BY ALMOST 30% BETWEEN 1988
AND 1997, ASSETS HELD BY INDUSTRY LEADERS HAVE CONSISTENTLY INCREASED, WHICH MAY
      GIVE THESE WELL-POSITIONED COMPANIES ADDED PROFITS AND EFFICIENCIES.

           SOURCE: REPORTS OF INCOME AND CONDITION AND NIC, 1988-1997,
            FDIC HISTORICAL STATISTICS ON BANKING, AND MEYER, 1988.
--------------------------------------------------------------------------------

THE CGAM RESEARCH PROCESS DEFINED

We look to  differentiate  ourself from the  traditional  approach to investment
management in a number of ways that we can add value to our clients' portfolios.
Our management  style can best be described as  disciplined,  yet flexible.  Our
formidable  global reach and local expertise enable us to nurture research teams
with direct  access to the regions and  industries  where they do business.  Our
research  organization  is centered on a team  approach  to stock  research  and
selection by covering  hundreds of companies and working  closely  together both
within  and  across  industry  teams in a  seamless  fashion  to reach a prudent
consensus.

Each stock analyst builds intensive,  detailed company models from the ground up
that seek to anticipate a particular  company's  future  financial  performance.
These  models  are  based  on the  company's  competitive  position  within  the
industry,  quality of product offerings, costs and risks. These intensive models
detail the analyst's  assumptions  for potential  profitability  for the company
going forward and provide some of the necessary  information to forecast company
fundamentals and make stock  recommendations.  Our research team looks to ensure
consistency  in industry and accounting  assumptions  and that in turn can allow
for better comparisons of earnings forecasts.

A common  valuation  framework--based  on the Dividend  Discount  Model  ("DDM")
allows for estimation of returns to fair value.  Simply stated, the DDM compares
a company's future discounted dividend stream to its current stock price.



   5 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

We  believe  this  is a  valuable  and  consistent  method  to  provide  current
valuations  to  securities.  The  DDM-based  valuation  process,  in their view,
provides a common  yardstick that helps analysts and portfolio  managers compare
the relative  valuation of one company's  stock to another.  The equity  analyst
then combines the DDM valuation together with other fundamental  factors such as
earnings surprises to come up with an investment rating on a company's stock.


--------------------------------------------------------------------------------
 ECONOMISTS ESTIMATE THAT THE LARGEST PERIOD OF WEALTH TRANSFER IN HISTORY WILL
        OCCUR AS AMERICANS TRANSFER $41 TRILLION OVER THE NEXT 55 YEARS.

               SOURCE: HAVENS AND SCHERVISH, BOSTON COLLEGE, 1999
--------------------------------------------------------------------------------

FINANCIAL SERVICES SECTOR UPDATE

The  financial  service  sector  experienced  high levels of  volatility  due to
concerns  regarding the state of capital markets  worldwide,  telecommunications
debt and the slowing growth of the U.S. economy during the period. However, more
recently, the performance of the sector improved as investors realized that some
of the fears were overdone.  Third quarter  results from U.S. banks  highlighted
some credit  quality  concerns but they were largely  restricted  to  syndicated
lending.  Banks which have limited exposure to syndicated lending and which have
been  executing  as per  plan  on  their  acquisitions  are  being  rewarded  by
investors.  Brokerage  stocks had a rough ride on concerns about slowing capital
markets  activity  and on their  holding  of  telecom  debt,  but they are still
outperforming  the sector year to date.  U.S.  insurers have generally  reported
strong  numbers,  on the back of firmer  pricing in property and  casualty,  and
solid domestic and international sales in the life and annuity group.

The financial  services sector has also been largely  characterized by increased
mergers and acquisition activity during the period. The recent blockbuster deals
between Credit Suisse First Boston and Donaldson,  Lufkin & Jenrette, Union Bank
of Switzerland and PaineWebber, and between Chase Manhattan Bank and J.P. Morgan
continue  the  pattern of rapid  consolidation  that has  radically  altered the
financial services industry in recent years.

Other deals that have shaped the sector include the  FleetBoston-Summit  merger,
the  Firstar-US  Bancorp  merger,  and  the  Danske-RealDanmark   merger.  These
acquisitions  reinforce  our belief that the  financial  services  industry  may
continue to consolidate globally over the near term.

The Fund remains diversified within the financial services sector as it looks to
own a number of  stocks in the many  industries  that make up the  sector,  most
notably,  banks,  insurance,  diversified  financial  companies  and real estate
investment trusts.  Within the sector, the Fund is slightly overweight (relative
to the  benchmark)  in life  insurer  American  General  and  Federal  Home Loan
Mortgage  Corporation  ("Freddie Mac"), while underweight  property and casualty
insurers,  securities  firms,  asset management firms and real estate investment
trusts ("REITs").

Although the Fund is  underweight  in securities  firms,  we maintain a positive
outlook on Knight Trading, the largest independent securities market maker. With
the  recent   consolidations   in  this  area,  we  believe  Knight  Trading  is
well-positioned  to either be acquired at a premium--since  they are a top-notch
firm with great  systems  and  execution  capabilities--or  to  continue to earn
superior returns due to their technology infrastructure investments. (Of course,
no guarantees can be given that our expectations will be met.)


   6 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
 EACH CGAM ANALYST BUILDS INTENSIVE, DETAILED COMPANY MODELS FROM THE GROUND UP
  THAT SEEK TO ANTICIPATE A PARTICULAR COMPANY'S FUTURE FINANCIAL PERFORMANCE.
--------------------------------------------------------------------------------

Although we look to identify those companies held in the Fund through  bottom-up
research and stock  selection,  our overall  industry mix is consistent with the
top-down   strategic   industry   themes   (demographics,    consolidation   and
technological  innovation)  which we use for  estimate  forecasting  and  rating
formulation.  Since the  financial  services  industry is dynamic,  we carefully
monitor the Fund's  holdings  to reflect any changes  that may have an impact on
performance.

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT

The management of the Fund is driven by our analyst  recommendations,  long-term
earnings and earnings momentum,  which form the basis of expected future returns
within any given  sector.  These  expected  returns,  coupled with detailed risk
forecasts, determine what holdings will be selected. In building and maintaining
the Fund's portfolio, we look to avoid a high risk-to-return on its investments,
and carefully monitor sector  performance,  constantly  looking for any material
changes and/or developments.

Thank you for  investing in the Smith Barney Sector  Series  Inc.--Smith  Barney
Financial  Services  Fund. We look forward to helping you pursue your  financial
goals in the years ahead.

Sincerely,

The Investment Team at
Citibank N.A.

NOVEMBER 7, 2000


   7 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS                                         OCTOBER 31, 2000
--------------------------------------------------------------------------------

     SHARES                         SECURITY                              VALUE
--------------------------------------------------------------------------------
COMMON STOCK -- 99.3%

BANKS -- 37.1%
         26,790     Amsouth Bancorp                                   $  373,386
         12,649     BB&T Corp.                                           403,187
         64,585     Bank of America Corp.                              3,104,117
         12,578     Bank of Montreal                                     583,305
         26,436     Bank of New York                                   1,521,722
         41,667     Bank One Corp.                                     1,520,845
         17,202     Canadian Imperial Bank                               546,163
         42,785     Chase Manhattan Corp.                              1,946,717
          7,047     Comerica                                             425,022
         42,632     First Union Corp.                                  1,292,282
         39,400     Firstar Corp.                                        775,687
         15,297     Fleet Boston Financial Corp.                         581,286
         25,840     Huntington Bancshares Inc.                           371,450
          6,579     J.P. Morgan & Co. Inc.                             1,088,824
         16,510     KeyCorp                                              407,591
          7,160     M & T Bank Corp.                                     359,432
          8,225     Marshall & Ilsley Corp.                              372,695
         19,519     Mellon Financial Corp.                               941,792
         23,482     National City Corp.                                  501,928
          7,824     Northern Trust Corp.                                 667,974
          8,852     PNC Financial Services Group                         591,977
         16,509     Regions Financial Corp.                              388,993
         27,290     Royal Bank of Canada                                 863,046
         11,749     Southtrust Corp.                                     380,374
          5,100     State Street Corp.                                   636,174
         26,680     Suntrust Banks Inc.                                1,302,318
         24,161     Synovus Financial Corp.                              520,972
         22,781     Toronto Dominion Bank                                627,901
         18,083     Unionbancal Corp.                                    379,743
         76,694     Wells Fargo & Co.                                  3,551,891
          6,863     Zions Bancorp                                        394,194
--------------------------------------------------------------------------------
                                                                      27,422,988
--------------------------------------------------------------------------------
BROKERS & INVESTMENT MANAGERS -- 13.9%
          6,163     Bear Stearns Companies Inc.                          373,632
         45,774     Charles Schwab Corp.                               1,607,812
          9,889     Franklin Resources Inc.                              423,645
         15,757     Goldman Sachs Group Inc.                           1,572,746
         18,773     Knight Trimark Group Inc. (a)                        562,017
          8,262     Lehman Brothers Holdings Inc.                        532,899
         25,290     Merrill Lynch & Co. Inc.                           1,770,300
         33,206     Morgan Stanley Dean Witter & Co.                   2,666,857
          8,413     Price, T. Rowe & Associates Inc.                     393,834
         22,084     TD Waterhouse Group Inc. (a)                         365,766
--------------------------------------------------------------------------------
                                                                      10,269,508
--------------------------------------------------------------------------------

CONSUMER SERVICES -- 1.1%
         10,420     H&R Block Inc.                                       371,864
          7,920     U.S.A. Education Inc.                                442,530
--------------------------------------------------------------------------------
                                                                         814,394
--------------------------------------------------------------------------------

                       SEE NOTES TO FINANCIAL STATEMENTS.

   8 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                             OCTOBER 31, 2000
--------------------------------------------------------------------------------

     SHARES                         SECURITY                              VALUE
--------------------------------------------------------------------------------
FINANCIAL COMPANIES & SERVICES -- 17.0%

         17,117     Axa Financial Inc.                               $   925,388
         49,647     American Express Co.                               2,978,820
         24,857     Associates First Capital Corp.                       922,816
          6,717     Capital One Financial Corp.                          424,011
         34,891     Federal Home Loan Mortgage Corp.                   2,093,460
         35,213     Federal National Mortgage Association              2,711,401
         16,970     Household International Inc.                         853,803
         29,294     MBNA Corp.                                         1,100,356
          5,461     Providian Financial Corp.                            567,944
--------------------------------------------------------------------------------
                                                                      12,577,999
--------------------------------------------------------------------------------
INSURANCE -- 25.5%
          9,390     Aflac Inc.                                           686,057
         24,148     Allstate Corp.                                       971,957
         18,783     American General Corp.                             1,512,031
         36,738     American International Group                       3,600,324
         11,285     Aon Corp.                                            467,622
             48     Berkshire Hathaway Inc., Cl. A (a)                 3,057,600
          4,561     Cigna Corp.                                          556,214
          9,736     Cincinnati Financial Corp.                           357,798
          8,096     Hartford Financial Services Group                    602,646
          5,597     Jefferson Pilot Corp.                                384,794
         21,604     Lincoln National Corp.                             1,045,093
         14,187     Loews Corp.                                        1,290,130
          5,121     MBIA Inc.                                            372,233
          6,594     MGIC Investment Corp.                                449,216
          9,708     Marsh & McLennan Companies Inc.                    1,269,321
         16,302     Protective Life Corp.                                376,984
          9,560     St. Paul Companies Inc.                              489,950
         24,849     Unumprovident Corp.                                  701,984
          8,465     XL Capital Ltd.                                      650,747
--------------------------------------------------------------------------------
                                                                      18,842,701
--------------------------------------------------------------------------------
REAL ESTATE -- 2.6%
         16,153     Archstone Communities Trust                          380,605
         11,915     Equity Office Properties Trust                       358,939
         37,263     Prologis Trust                                       782,523
         13,357     Starwood Hotels and Resorts                          395,701
--------------------------------------------------------------------------------
                                                                       1,917,768
--------------------------------------------------------------------------------
SAVINGS & LOAN -- 2.1%
         10,160     Golden West Financial Corp.                          569,595
         21,545     Washington Mutual Inc.                               947,980
--------------------------------------------------------------------------------
                                                                       1,517,575
--------------------------------------------------------------------------------
                    TOTAL COMMON STOCK
                    (Identified Cost-- $62,469,866)                   73,362,933
================================================================================

                       SEE NOTES TO FINANCIAL STATEMENTS.

   9 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                             OCTOBER 31, 2000
--------------------------------------------------------------------------------
      FACE
     AMOUNT                         SECURITY                              VALUE
--------------------------------------------------------------------------------
DISCOUNT NOTE -- 0.7%
     $ 492,000      Student Loan Marketing Discount Note
                      6.45% due 11/01/00
                      (Identified Cost-- $492,000)                   $   492,000
================================================================================
                    TOTAL INVESTMENTS -- 100%
                    (Identified Cost-- $62,961,866)*                 $73,854,933
================================================================================
(a) NON-INCOME PRODUCING SECURITY.
 *  AGGREGATE COST FOR FEDERAL INCOME TAXES IS SUBSTANTIALLY THE SAME.





                       SEE NOTES TO FINANCIAL STATEMENTS.

  10 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
STATEMENT OF ASSETS AND LIABILITIES                             OCTOBER 31, 2000
--------------------------------------------------------------------------------

ASSETS:
     Investments, at value (Cost  $62,961,866)                       $73,854,933
     Cash                                                                    238
     Receivable for securities sold                                    6,548,350
     Receivable for fund shares sold                                     378,605
     Dividends and interest receivable                                    74,769
--------------------------------------------------------------------------------
     TOTAL ASSETS                                                     80,856,895
--------------------------------------------------------------------------------
LIABILITIES:
     Payable for securities purchased                                  6,839,347
     Distribution fees payable                                            49,896
     Management fees payable                                               4,507
     Payable for Fund shares repurchased                                     100
     Accrued expenses and other liabilities                              127,746
--------------------------------------------------------------------------------
     TOTAL LIABILITIES                                                 7,021,596
--------------------------------------------------------------------------------
TOTAL NET ASSETS                                                     $73,835,299
================================================================================
NET ASSETS:
     Par value of capital shares                                     $     4,666
     Capital paid in excess of par value                              60,482,287
     Undistributed net investment income                                  87,112
     Accumulated net realized gain from security transactions          2,373,977
     Net unrealized appreciation of investments                       10,887,257
--------------------------------------------------------------------------------
TOTAL NET ASSETS                                                     $73,835,299
================================================================================

SHARES OUTSTANDING:
     Class A                                                             898,679
     ---------------------------------------------------------------------------
     Class B                                                           1,815,227
     ---------------------------------------------------------------------------
     Class L                                                           1,952,207
     ---------------------------------------------------------------------------

NET ASSET VALUE:
     Class A (and redemption price)                                       $15.89
     ---------------------------------------------------------------------------
     Class B *                                                            $15.81
     ---------------------------------------------------------------------------
     Class L **                                                           $15.81
     ---------------------------------------------------------------------------

MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
     Class A (net asset value plus 5.26% of
       net asset value per share)                                         $16.73
     ---------------------------------------------------------------------------
     Class L (net asset value plus 1.01% of
       net asset value per share)                                         $15.97
================================================================================
  * REDEMPTION  PRICE IS NAV OF CLASS B SHARES REDUCED BY A 5.00% CDSC IF SHARES
    ARE REDEEMED LESS THAN ONE YEAR FROM INITIAL PURCHASE (SEE NOTE 2).

 ** REDEMPTION  PRICE IS NAV OF CLASS L SHARES REDUCED BY A 1.00% CDSC IF SHARES
    ARE REDEEMED WITHIN THE FIRST YEAR OF PURCHASE.

                       SEE NOTES TO FINANCIAL STATEMENTS.

  11 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF OPERATIONS
--------------------------------------------------------------------------------

FOR THE PERIOD FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

INVESTMENT INCOME:
     Dividends                                                      $   670,403
     Interest                                                            41,152
     Less: Foreign withholding tax                                       (5,838)
-------------------------------------------------------------------------------
     TOTAL INVESTMENT INCOME                                            705,717
-------------------------------------------------------------------------------

EXPENSES:
     Distribution fees(Note 2)                                          276,571
     Management fees (Note 2)                                           260,242
     Custody fees                                                       170,543
     Shareholder communications                                          39,237
     Legal fees                                                          34,871
     Registration fees                                                   21,642
     Audit fees                                                          17,667
     Directors' fees                                                      7,727
     Other                                                               38,306
-------------------------------------------------------------------------------
     TOTAL EXPENSES                                                     866,806
     Less: Aggregate amount waived by the Manager (Note 2)             (179,543)
-------------------------------------------------------------------------------
     NET EXPENSE                                                        687,263
-------------------------------------------------------------------------------

NET INVESTMENT INCOME                                                    18,454
-------------------------------------------------------------------------------

REALIZED AND UNREALIZED GAIN ON INVESTMENTS (NOTE 3):
     Realized Gain From:
        Security transactions (excluding short-term securities)       2,373,977
-------------------------------------------------------------------------------
     Increase in Net Unrealized Appreciation                         10,887,257
-------------------------------------------------------------------------------
NET GAIN ON INVESTMENTS                                              13,261,234
-------------------------------------------------------------------------------
INCREASE IN NET ASSETS FROM OPERATIONS                              $13,279,688
================================================================================

                       SEE NOTES TO FINANCIAL STATEMENTS.

  12 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------

FOR THE PERIOD FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

OPERATIONS:
     Net investment income                                          $    18,454
     Net realized gain                                                2,373,977
     Increase in net unrealized appreciation                         10,887,257
-------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM OPERATIONS                          13,279,688
-------------------------------------------------------------------------------

FUND SHARE TRANSACTIONS (NOTE 6):
     Net proceeds from sale of shares                                67,499,965
     Net asset value of shares issued for reinvestment of dividends          --
     Cost of shares reacquired                                       (6,944,354)
-------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS             60,555,611
-------------------------------------------------------------------------------

INCREASE IN NET ASSETS                                               73,835,299

NET ASSETS:
     Beginning of period                                                     --
-------------------------------------------------------------------------------
     END OF PERIOD*                                                 $73,835,299
===============================================================================
* Includes undistributed net investment income of:                  $    87,112
===============================================================================

                       SEE NOTES TO FINANCIAL STATEMENTS.

  13 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1. Significant Accounting Policies

The Smith Barney Financial Services Fund is a non-diversified investment fund of
the Smith Barney Sector Series Inc. (the "Company"), a Maryland corporation. The
Company is registered  under the Investment  Company of 1940, as amended,  as an
open-end management  investment company and consists of this Fund and five other
separate  investment  funds:  Smith Barney Health  Sciences  Fund,  Smith Barney
Technology  Fund,  Smith Barney Global  Biotechnology  Fund, Smith Barney Global
Media &  Telecommunications  Fund and Smith Barney  Global  Technology  Fund. On
February 28, 2000, the Fund commenced of operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed  to be  over-the-counter)  and the  securities  for  which  no sale was
reported  on that date are valued at the mean  between  the bid and ask  prices.
Securities  which are listed or traded on more than one  exchange  or market are
valued at the quotations on the exchange or market  determined to be the primary
market for such securities;  (c) securities for which market  quotations are not
available  will be valued  in good  faith at fair  market  value by or under the
direction of the Board of Directors;  (d) securities maturing within 60 days are
valued  at cost  plus  accreted  discount,  or minus  amortized  premium,  which
approximates  value;  (e) the  accounting  records of the Fund are maintained in
U.S. dollars.  All assets and liabilities  denominated in foreign currencies are
translated  into U.S.  dollars based on the rate of exchange of such  currencies
against  U.S.  dollars  on  the  date  of  valuation.  Purchases  and  sales  of
securities,  and income and  expenses  are  translated  at the rate of  exchange
quoted on the respective date that such  transactions are recorded.  Differences
between  income or expense  amounts  recorded and collected or paid are adjusted
when reported by the custodian;  (f) interest income,  adjusted for amortization
of premium and  accretion  of  discount,  is recorded on an accrual  basis;  (g)
dividend  income is recorded on the  ex-dividend  date;  foreign  dividends  are
recorded  on the  ex-dividend  date or as  soon  as  practical  after  the  Fund
determines the existence of a dividend  declaration after exercising  reasonable
due diligence:  (h) dividends and  distributions to shareholders are recorded on
the  ex-dividend  date;  (i)  gains  or  losses  on the sale of  securities  are
calculated by using the specific indentification method; (j) direct expenses are
charged to each class; management fees and general expenses are allocated on the
basis of  relative  net  assets;  (k) the  character  of income  and gains to be
distributed are determined in accordance  with income tax regulations  which may
differ from generally accepted  accounting  principles;  (l) the Fund intends to
comply with the  requirements of the Internal  Revenue Code of 1986, as amended,
pertaining  to  regulated  investment  companies  and to make  distributions  of
taxable income  sufficient to relieve it from  substantially  all Federal income
and excise  taxes;  (m) the character of income and gains to be  distributed  in
accordance with income tax regulations which may differ from generally  accepted
accounting principles.  At October 31, 2000,  reclassifications were made to the
Funds' capital accounts to reflect permanent book/tax  difference and income and
gains available for distribution under income tax regulations.  Accordingly, the
Fund  reclassified  $68,658 from paid in capital to undistributed net investment
income.  Net  investment  income,  net  realized  gains and net assets  were not
affected by this adjustment and (n) estimates and assumptions are required to be
made  regarding  assets,  liabilities  and changes in net assets  resulting from
operations  when  financial  statements  are  prepared.  Changes in the economic
environment,  financial  markets and any other  parameters  used in  determining
these estimates could cause actual results to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market  rate as an  unrealized  gain or  loss.  Realized  gains  or  losses  are
recognized when contracts are settled.


  14 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------


2.   Management Agreement and Other Transactions

SSB Citi Fund  Management  LLC  ("SSBC"),  a subsidiary  of Salomon Smith Barney
Holdings  Inc.  ("SSBH"),  which,  in turn,  is a subsidiary  of Citigroup  Inc.
("Citigroup"),  acts as investment  manager to the Fund.  The  management fee is
computed at an annual rate of 0.80% of the  average  daily net assets.  SSBC has
delegated  the  daily  management  of  the  Portfolio  to  Citibank  N.A.,  (the
"SubAdviser"),  an affiliate of SSBC.  For  services  provided to the Fund,  the
manager  pays the  Subadviser  a  subadvisory  fee computed at an annual rate of
0.50% of the Fund's average daily net assets.  The management fees paid amounted
to $260,242, of which $179,543 was waived for the period ended October 31, 2000.

Salomon  Smith Barney Inc.  ("SSB"),  another  subsidiary  of SSBH,  acts as the
Fund's distributor,  as well as certain other broker-dealers,  continues to sell
Fund shares to the public as a member of the selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and PFPC Global Fund  Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTC receives fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $22,796 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
================================================================================
CDSCs                      $   1,000      $16,000      $ 13,000
--------------------------------------------------------------------------------
Sales Charges                219,000       68,000       262,000
================================================================================

Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
================================================================================
Distribution Plan Fees       $16,244      $126,651     $133,676
================================================================================

All officers and one Director of the Fund are employees of SSB.


3. Investments

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

================================================================================
Purchases                                                           $72,397,162
--------------------------------------------------------------------------------
Sales                                                               $12,301,238
================================================================================

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

================================================================================
Gross unrealized appreciation                                       $11,811,518
Gross unrealized depreciation                                          (918,451)
--------------------------------------------------------------------------------
Net unrealized appreciation                                         $10,893,067
================================================================================

  15 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

4. Repurchase Agreements

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Fund requires continual  maintenance
of the market  value of the  collateral  (plus  accrued  interest) in amounts at
least equal to the repurchase price.


5. Concentration of Risk

The Fund  normally  invests  at least 80% of its  assets in  financial  services
related  investments.  As a  result  of this  concentration  policy,  which is a
fundamental policy of the Fund, the Fund's investments may be subject to greater
risk and market fluctuation than a fund that invests in securities  representing
a broader range of investment alternatives.

The Fund's  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S. dollar can  significantly  affect the value of these investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.


6. Capital Shares

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.

At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:

                             CLASS A      CLASS B      CLASS L
================================================================================
Total Paid-in Capital    $11,621,388   $23,464,394  $25,469,829
================================================================================


Transactions in shares of each class were as follows:

                                                       FEBRUARY 28, 2000
                                                 (COMMENCEMENT OF OPERATIONS)
                                                      TO OCTOBER 31, 2000
                                              ----------------------------------
                                               SHARES                 AMOUNT
================================================================================
CLASS A
Shares sold                                   1,080,686            $ 14,251,729
Shares issued on reinvestment                        --                      --
Shares reacquired                              (182,007)             (2,630,341)
--------------------------------------------------------------------------------
Net Increase                                    898,679            $ 11,621,388
================================================================================
CLASS B
Shares sold                                   1,940,132            $ 25,240,302
Shares issued on reinvestment                        --                      --
Shares reacquired                              (124,905)             (1,775,908)
--------------------------------------------------------------------------------
Net Increase                                  1,815,227            $ 23,464,394
================================================================================
CLASS L
Shares sold                                   2,129,426            $ 28,007,934
Shares issued on reinvestment
Shares reacquired                              (177,219)             (2,538,105)
--------------------------------------------------------------------------------
Net Increase                                  1,952,207            $ 25,469,829
================================================================================


  16 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS A SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                      $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment income                                    0.05
   Net realized and unrealized gain                         4.44
--------------------------------------------------------------------------------
Total Income From Operations                                4.49
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                     --
   Net realized gain                                         --
--------------------------------------------------------------------------------
Total Distributions                                          --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                           $15.89
--------------------------------------------------------------------------------
TOTAL RETURN                                              39.39%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                        $14,276
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                               1.51%+
   Net investment income                                  0.69%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                     26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

      Net investment income per share                    $0.05
      RATIOS:
      Expenses to average net assets                      2.06%+
      Net investment income to average net assets         0.14%+
================================================================================
    + ANNUALIZED.
   ++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE
      TOTAL RETURN FOR THE YEAR.




                       SEE NOTES TO FINANCIAL STATEMENTS.

  17 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS B SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                    $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                   (0.01)
   Net realized and unrealized gain                       4.42
--------------------------------------------------------------------------------
Total Income From Operations                              4.41
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                    --
   Net realized gain                                        --
--------------------------------------------------------------------------------
Total Distributions                                         --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                          $15.81
--------------------------------------------------------------------------------
TOTAL RETURN                                             38.68%++
NET ASSETS, END OF PERIOD (000S)                       $28,696
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                               2.26%+
   Net investment loss                                   (0.07)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                     26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                     $(0.06)
      RATIOS:
      Expenses to average net assets                      2.81%+
      Net investment loss to average net assets          (0.62)%+
================================================================================
  + ANNUALIZED.
 ++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
    RETURN FOR THE YEAR.


                       SEE NOTES TO FINANCIAL STATEMENTS.

  18 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS L SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                    $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                   (0.01)
   Net realized and unrealized gain                       4.42
--------------------------------------------------------------------------------
Total Income From Operations                              4.41
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                    --
   Net realized gain                                        --
--------------------------------------------------------------------------------
Total Distributions                                         --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                          $15.81
--------------------------------------------------------------------------------
TOTAL RETURN                                             38.68%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                       $30,863
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                               2.26%+
   Net investment loss                                   (0.08)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                     26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                     $(0.07)
      RATIOS:
      Expenses to average net assets                      2.81%+
      Net investment loss to average net assets          (0.63)%+
================================================================================
 + ANNUALIZED.
++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.



                       SEE NOTES TO FINANCIAL STATEMENTS.

  19 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
INDEPENDENT AUDITORS` REPORT
--------------------------------------------------------------------------------

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTORS SERIES INC.

We have audited the accompanying statement of assets and liabilities,  including
the schedule of investments,  of Smith Barney  Financial  Services Fund of Smith
Barney  Sectors  Series Inc. as of October 31, 2000,  the related  statements of
operations,  changes  in net  assets  and  financial  highlights  for the period
February 28, 2000  (Commencement of Operations)  through October 31, 2000. These
financial  statements  and financial  highlights are the  responsibility  of the
Fund's  management.  Our  responsibility  is to  express  an  opinion  on  these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney Financial Services Fund of Smith Barney Sectors Series Inc. as of October
31,  2000,  the  results of its  operations,  the  changes in its net assets and
financial  highlights for the period February 28, 2000 through October 31, 2000,
in conformity with accounting principles generally accepted in the United States
of America.



/s/ KPMG LLP
------------

New York, New York
December 11, 2000




  20 SMITH BARNEY FINANCIAL SERVICES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY
FINANCIAL SERVICES FUND
--------------------------------------------------------------------------------

    DIRECTORS
    Herbert Barg
    Alfred J. Bianchetti
    Martin Brody
    Dwight B. Crane
    Burt N. Dorsett
    Elliot S. Jaffe
    Stephen E. Kaufman
    Joseph J. McCann
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.
    James J. Crisona, Emeritus

    OFFICERS
    Heath B. McLendon
    President and Chief Executive Officer

    Lewis E. Daidone
    Senior Vice President and Treasurer

    Irving P. David
    Controller

    Christina T. Sydor
    Secretary



    INVESTMENT MANAGER
    SSB Citi Fund Management LLC

    INVESTMENT SUBADVISER
    Citibank, N.A.

    DISTRIBUTORS
    Salomon Smith Barney, Inc.
    PFS Distributors Inc.

    CUSTODIAN
    State Street Bank & Trust Co.

    TRANSFER AGENT
    Citi Fiduciary Trust Company
    125 Broad Street, 11th Floor
    New York, New York 10004

    SUB-TRANSFER AGENT
    PFPC Global Fund Services
    P.O. Box 9699
    Providence, Rhode Island
    02940-9699


<PAGE>

SMITH BARNEY FINANCIAL SERVICES FUND
--------------------------------------------------------------------------------

This report is submitted for general information of the shareholders of Smith
Barney Sector Series Inc. -- Smith Barney Financial Services Fund, but it may
also be used as sales literature when preceded or accompanied by the current
Prospectus, which gives details about charges, expenses, investment objectives
and operating policies of the Fund. If used as sales material after January 31,
2001, this report must be accompanied by performance information for the most
recently completed calendar quarter.

SMITH BARNEY FINANCIAL SERVICES FUND
Smith Barney Mutual Funds
388 Greenwich Street, MF-2
New York, New York 10013


For complete information on any Smith Barney Mutual Funds, including management
fees and expenses, call or write your financial professional for a free
prospectus. Read it carefully before you invest or send money.

www.smithbarney.com/mutualfunds



[SALOMON SMITH BARNEY LOGO]

Salomon Smith Barney is a service mark of Salomon Smith Barney Inc.

FD02127 12/00


<PAGE>

--------------------------------------------------------------------------------
                                  SMITH BARNEY
                               SECTOR SERIES INC.

                              HEALTH SCIENCES FUND
--------------------------------------------------------------------------------

               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000



[LOGO OMITTED]   SMITH BARNEY MUTUAL FUNDS
                 YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)


--------------------------------------------------------------------------------
             NOT FDIC INSURED o NOT BANK GUARANTEED o MAY LOSE VALUE
--------------------------------------------------------------------------------
<PAGE>

[GRAPHIC] Research Series

Annual Report o October 31, 2000

SMITH BARNEY HEALTH SCIENCES FUND

CITIBANK GLOBAL ASSET MANAGEMENT

Citibank,  N.A.,  through its Citibank Global Asset  Management  division is the
subadviser to the Fund. Comprised of a seasoned group of investment and research
professionals,  the Fund's  management  team follows a  systematic  and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks long-term capital  appreciation by investing  primarily in common
stocks.  The Fund  normally  invests at least 80% of its assets in securities of
companies principally engaged in the design, manufacturing,  or sale of products
or services used for or in connection with health care or medicine.

FUND FACTS

FUND INCEPTION
--------------------------------------------------------------------------------
February 28, 2000

               CLASS A     CLASS B    CLASS L
--------------------------------------------------------------------------------
NASDAQ         N/A         SBHBX      SBHLX
--------------------------------------------------------------------------------
INCEPTION      2/28/00     2/28/00    2/28/00
--------------------------------------------------------------------------------


SMITH BARNEY HEALTH SCIENCES FUND*
TOTAL RETURNS AS OF OCTOBER 31, 2000

                                 WITHOUT SALES CHARGES(1)

                               Class A    Class B    Class L
--------------------------------------------------------------------------------
Since Inception
(February 28, 2000)**           27.11%     26.49%    26.49%
--------------------------------------------------------------------------------

                                  WITH SALES CHARGES(2)

                               Class A    Class B    Class L
--------------------------------------------------------------------------------
Since Inception
(February 28, 2000)**           20.75%     21.49%    24.23%
--------------------------------------------------------------------------------


*    Since the Fund focuses its investments on companies involved in the health
     sciences, an investment in the Fund may involve a greater degree of risk
     than an investment in other mutual funds with greater diversification.

**   Not Annualized

(1)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value and does not reflect deduction of all applicable
     sales charges with respect to Class A and L shares of the applicable
     contingent deferred sales charges ("CDSC") with respect to Class B and L
     shares.

(2)  Assumes reinvestment of all dividends and capital gain distributions, if
     any at net asset value. In addition, Class A and L shares reflect the
     deduction of the maximum sales charge of 5.00% and 1.00%, respectively; and
     Class B shares reflect the deduction of a 5.00% CDSC, which applies if
     shares are redeemed within one year from initial purchase. Thereafter, this
     CDSC declines by 1.00% per year until no CDSC is incurred. Class L shares
     also reflect the deduction of 1.00% per year until no CDSC is incurred.
     Class L shares also reflect the deduction of 1.00% CDSC, which applies if
     shares are redeemed within the first year of purchase.

WHAT'S INSIDE

Your Investment in the Smith Barney
Health Sciences Fund ..................................1
Letter from the Chairman ..............................2
Fund at a Glance ......................................3
Shareholder Letter ....................................4
Schedule of Investments ...............................8
Statement of Assets and Liabilities ..................10
Statement of Operations ..............................11
Statement of Changes in Net Assets ...................12
Notes to Financial Statements ........................13
Financial Highlights .................................16
Independent Auditors' Report .........................19

[LOGO OMITTED]  SMITH BARNEY MUTUAL FUNDS
                YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)

--------------------------------------------------------------------------------
  Investment Products: Not FDIC Insured o Not Bank Guaranteed o May Lose Value
--------------------------------------------------------------------------------
<PAGE>

--------------------------------------------------------------------------------
            YOUR INVESTMENT IN THE SMITH BARNEY HEALTH SCIENCES FUND
--------------------------------------------------------------------------------

Led by Citibank N.A. through its Global Asset Management ("CGAM") division the
Fund offers investors the opportunity to participate in the long-term growth
potential of the health sciences industry. The Fund's management team is
comprised of a seasoned group of investment and research professionals who
follow a systematic and rigorous approach designed to provide appropriate
exposure to each market sector.

[GRAPHIC OMITTED]
   POPULATION CHANGES CAUSING DEMAND TO RISE

   Americans are living longer than ever before, and because spending on
   healthcare typically increases with age, the demand for health services and
   products is expected to rise. Offering investors a convenient way to
   participate in the potential growth of this sector, CGAM carefully monitors
   new trends and shifting demands related to healthcare.

[GRAPHIC OMITTED]
   DIVERSIFICATION IN A TARGETED SECTOR*

   An investment in the Fund offers investors a way to invest in a broad range
   of companies in the health sciences sector. The Fund's investments may
   include companies in a wide range of industries such as biotechnology,
   pharmaceuticals and managed healthcare.

[GRAPHIC OMITTED]
   THE BENEFITS OF EXHAUSTIVE FUNDAMENTAL SECURITIES ANALYSIS--THE RESEARCH
   SERIES

   The Research Series is a selection of Smith Barney Mutual Funds built on a
   foundation of substantial buy-side research under the direction of CGAM. This
   series of funds focus on potential opportunities from well-defined
   industries, sectors and trends.

[GRAPHIC OMITTED]
   A COMMITMENT TO MANAGING YOUR SERIOUS MONEY

   SSB Citi Asset Management Group ("SSB Citi"), the investment management
   division of Citigroup, comprises Smith Barney Asset Management, Salomon
   Brothers Asset Management and Citibank Global Asset Management, each an
   organization with extensive investment capabilities.

   SSB Citi, as a member of one of the largest financial services providers in
   the world, offers you the benefits of our unparalleled global capabilities.

   At SSB Citi, you gain access to portfolio management delivered
   professionally. We are proud to offer you, the serious investor, a variety of
   managed solutions.

*Please note that because the Fund invests in a single industry, its shares do
 not represent a complete investment program, and the value of its shares may
 fluctuate more than shares invested in a broader range of industries.

    1 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
                            LETTER FROM THE CHAIRMAN
--------------------------------------------------------------------------------

The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks may be running  out of steam.  At SSB Citi Asset
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.

We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their businesses. Today, with over $398.6 billion in assets under management,(1)
SSB Citi offers  choices and  solutions,  uniting the  distinguished  history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.

A FEW THOUGHTS ON SECTOR INVESTING

Over the past few years,  we have seen how profoundly the  advancements  made in
the healthcare  sector have transformed our daily lives.  Many companies in this
sector may offer exceptional growth potential and many investors should consider
having a portion of their investment portfolios in them.

Although most of us recognize that certain sectors drive the economy, we believe
it is much more  difficult  to  determine  which  companies  within a particular
sector,  such as healthcare,  will perform better than the others over time. The
team of experienced professionals at Citibank N.A. thoroughly researches a broad
range of companies within a given sector and carefully analyzes them, looking to
identify those companies that they believe offer the greatest  growth  potential
over the long term. Through this exhaustive and proprietary process,  CGAM seeks
to offer you an opportunity  to participate in those  companies that it believes
are best-positioned in their respective industries.

[PHOTO OMITTED]
HEATH B. MCLENDON
CHAIRMAN

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.

When you  invest  with SSB  Citi,  you can do so with the  confidence  that your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.

Thank you for your confidence in our investment management approach.

Sincerely,


/s/ Heath B. McLendon
---------------------

Heath B. McLendon
Chairman

NOVEMBER 6, 2000




--------------------
(1) AS OF OCTOBER 31, 2000. THIS FIGURE REPRESENTS RETAIL, INSTITUTIONAL,  MONEY
    AND SEPARATE ACCOUNTS.


    2 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY HEALTH SCIENCES FUND AT A GLANCE (UNAUDITED)
--------------------------------------------------------------------------------

GROWTH OF $10,000 INVESTED IN SHARES OF THE
SMITH BARNEY HEALTH SCIENCES FUND VS. GOLDMAN SACHS HEALTHCARE INDEX
--------------------------------------------------------------------------------
       FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) -- OCTOBER 31, 2000

[Table below represents line chart in printed piece]

                                Class A       Healthcare Index*
                   2/28/00         9500                  10000
                                   9550                  10000
                   3/31/00         9450                   9932
                   4/28/00         9825                  10376
                   5/31/00        10225                10781.7
                   6/30/00      11391.7                11954.7
                   7/31/00      11016.7                11550.6
                   8/31/00        11375                11967.6
                   9/39/00      11858.3                12495.4
                   10/30/00       12075                12796.5


A $10,000  investment  in the Fund made on February 28, 2000 would have grown to
$12,075 with sales charge (as of October 31, 2000). The graph shows how the fund
compares to its  benchmark for the same period.  The graph  includes the initial
sales charge on the Fund (no comparable charge exists for the index) and assumes
all dividends and distributions are reinvested at Net Asset Value.

* The  Goldman  Sachs  Healthcare  Index is  comprised  of health  care  service
companies,  including  long-term  care  and  hospital  facilities,  health  care
management   organizations  and  continuing  care  services  and  pharmaceutical
companies. Please note that an investor cannot invest directly in an index.

              TOP TEN COMMON STOCK HOLDINGS*


 1. MERCK & CO., INC. ................................ 7.2%

 2. ELI LILLY & CO. .................................. 7.2

 3. PFIZER, INC. ..................................... 6.6

 4. JOHNSON & JOHNSON, INC. .......................... 6.1

 5. AMERICAN HOME PRODUCTS CORP. ..................... 5.4

 6. ABBOTT LABS ...................................... 5.4

 7. BRYSTOL MYERS-SQUIBB CO. ......................... 5.3

 8. MEDTRONIC, INC. .................................. 4.9

 9. SCHERING-PLOUGH CORP. ............................ 4.0

10. PHARMACIA & UPJOHN INC. .......................... 3.3


----------------------------------------------------------
                     PORTFOLIO BREAKDOWN*
----------------------------------------------------------

[Table below represents pie chart in printed piece]

 0.8% Precision Instruments
 1.4% Services to the Health Industry
 1.5% Multi-Line Insurance
 1.8% Generic Drugs
 2.5% Managed Healthcare
 3.0% Hospital Nursing Management
 3.1% Medical/Dental Distributions
 3.5% Pharmaceuticals
 4.9% Medical Electronics
10.9% Medical Specialties
16.1% Biotechnology
50.5% Major Pharmaceuticals


* As a percentage of total common stocks.

    3 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

DEAR SHAREHOLDER,

We are pleased to provide the annual  report for the Smith Barney  Sector Series
Inc.--Smith  Barney  Health  Sciences Fund ("Fund") for the period from February
28,  2000  through  October 31,  2000.  In this  report we have  summarized  the
period's  prevailing  economic and market conditions and outlined our investment
strategy.  The information provided in this letter represents the opinion of the
manager and is not  intended to be a forecast of future  events,  a guarantee of
future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 9 for a complete list and  percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE

From the period from  inception on February  28, 2000 through  October 31, 2000,
the Fund's Class A shares,  without and with sales charges,  returned 27.11% and
20.75%,  respectively.  In  comparison,  the Goldman Sachs  Healthcare  Index(1)
returned 27.97% for the same time period.

SECTOR INVESTING--THE CGAM PROCESS

Our approach to global sector investing is based on exhaustive  research that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive industry expertise.  Our team looks for analytical consistency through
intensive modeling and strict application of a consistent valuation methodology.

Our management team is made up of a group of high-quality,  seasoned, investment
and  research  professionals  who  follow a  systematic  and  rigorous  strategy
designed  to  provide  the right  exposure  to  various  industries  within  any
particular sector they cover. Our exhaustive  fundamental  research  evaluates a
universe of businesses in our global quest to identify and  participate  in what
we deem attractive investment opportunities.

                  A THREE-STEP RESEARCH PROCESS

           -----------    ------------    ----------------
           FUNDAMENTAL    QUANTITATIVE    ACTIVE PORTFOLIO
            RESEARCH        RESEARCH         MANAGEMENT
           -----------    ------------    ----------------

We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to  create  portfolios  that we think  should  generate  competitive
returns while helping to moderate risk over time.

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)

Our  fundamental,  proprietary  research  can  add  value  to  active  portfolio
management by providing timely and unbiased information to their decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

------------------
(1) THE GOLDMAN  SACHS  HEALTHCARE  INDEX IS  COMPRISED  OF HEALTH CARE  SERVICE
    COMPANIES,  INCLUDING  LONG-TERM CARE AND HOSPITAL  FACILITIES,  HEALTH CARE
    MANAGEMENT  ORGANIZATIONS  AND CONTINUING  CARE SERVICES AND  PHARMACEUTICAL
    COMPANIES. PLEASE NOTE THAT AN INVESTOR CANNOT INVEST DIRECTLY IN AN INDEX.

    4 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

o Superior products or services
o Outstanding managements
o Solid balance sheets
o Market leadership
o Leading innovation

In our opinion,  these are the companies'  strengths that can potentially create
real value and lead to strong earnings and sales growth, which ultimately drives
stock prices.


--------------------------------------------------------------------------------
            TECHNOLOGICAL ADVANCES HAVE LED THE WAY FOR INNOVATIONS
IN THE HEALTH SCIENCES SECTOR SUCH AS LASER EYE SURGERY, BALLOON ANGIOPLASTY AND
                          MINIMALLY INVASIVE SURGERY.
--------------------------------------------------------------------------------

THE CGAM RESEARCH PROCESS DEFINED

We look to  differentiate  ourself from the  traditional  approach to investment
management in a number of ways that we think we can add value to the  portfolio.
Our management  style can best be described as  disciplined,  yet flexible.  Our
formidable  global reach and local expertise enable us to nurture research teams
with direct  access to the regions and  industries  where they do business.  Our
research  organization  is centered on a team  approach  to stock  research  and
selection by covering  hundreds of companies and working  closely  together both
within  and  across  industry  teams in a  seamless  fashion  to reach a prudent
consensus.

Each stock analyst builds intensive,  detailed company models from the ground up
that anticipate a particular company's financial  performance.  These models are
based on the company's  competitive  position  within the  industry,  quality of
product offerings,  costs and risks. These intensive models detail the analyst's
assumptions  for  potential  profitability  for the  company  going  forward and
provides some of the necessary  information to forecast company fundamentals and
make stock  recommendations.  Our research team looks to ensure  consistency  in
industry  and  accounting  assumptions  and that in turn can  allow  for  better
comparisons of earnings forecasts.

A common valuation framework-based on the Dividend Discount Model ("DDM") allows
for  estimation  of returns to fair value.  Simply  stated,  the DDM  compares a
company's future discounted dividend stream to its current stock price.

We  believe  this  is a  valuable  and  consistent  method  to  provide  current
valuations to securities. The DDM-based valuation process, in our view, provides
a common  yardstick  that helps  analysts  and  portfolio  managers  compare the
relative  valuation of one company's  stock to another.  The equity analyst then
combines  the DDM  valuation  together  with other  fundamental  factors such as
earnings surprises to come up with an investment rating on a company's stock.


     5 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
  SINCE 1929, SPENDING ON HEALTH SCIENCES PRODUCTS AND SERVICES HAS INCREASED
 DRAMATICALLY AND IS EXPECTED TO CLIMB FOR THE NEXT 30 YEARS, AS AMERICANS LIVE
 LONGER AND A GREATER NUMBER OF THEM REACH AGE 65 AND BEYOND--THEIR PEAK HEALTH
                              CARE SPENDING DAYS.

            SOURCE: STATISTICAL ABSTRACT OF THE UNITED STATES, 1999.
--------------------------------------------------------------------------------

HEALTH SCIENCES SECTOR UPDATE

The health sciences sector performed well during the period,  as investors began
to shift their focus from technology stocks to stocks in the  pharmaceutical and
medical provider industries.  Most health care investors focused their attention
during the later part of the period on the upcoming U.S.  presidential  election
and its  potential  impact on Medicare  reform,  drug  coverage  topic that took
center stage.  However,  until a new  president is elected,  it is impossible to
determine the exact impact of proposed Medicare reform.

Relative  to the  sector,  the  Fund  has a  neutral  weighting  toward  medical
providers;  relative to the benchmark,  an overweight in product  companies like
Baxter International Inc., Medtronic, Inc. and Sybron International Corp.; and a
slight underweight in large pharmaceuticals. Though the Fund is underweighted in
pharmaceuticals  as a group,  we still  see  opportunities  in Eli  Lilly & Co.,
particularly  in comparison to other large  companies such as Merck & Co., Inc.,
Bristol  Myers-Squibb  Co. or American  Home  Products  Corp.  Eli Lilly will be
reporting on the trial results of its new sepsis  treatment in February 2001 and
we feel it will be  positive  for  stock  sentiment.  Other  pharmaceutical  and
biotechnology  companies  have not been able to  achieve  success  in this area,
which we believe  may lead to $2 billion  per year in  additional  sales for Eli
Lilly.  (Of course,  no guarantees  can be given that our  expectations  will be
met.)


--------------------------------------------------------------------------------
   THE MANAGEMENT OF THE FUND IS DRIVEN BY ANALYST RECOMMENDATIONS, LONG-TERM
 EARNINGS AND EARNINGS MOMENTUM FACTORS WHICH FORM THE BASIS OF EXPECTED FUTURE
                        RETURNS WITHIN ANY GIVEN SECTOR.
--------------------------------------------------------------------------------

We identify health sciences  companies we currently hold in the Fund's portfolio
through our  bottom-up  fundamental  research,  yet the overall  industry mix is
consistent  with  the  top-down  strategic  industry  themes,  which  we use for
estimate forecasting and rating formulation.  Since industries within the health
sciences sector are generally quick to react to medical  findings and conference
announcements,  we carefully  monitor the Fund's holdings to reflect any changes
that may have an impact on performance.

    6 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT

The  management  of the sector  funds is driven by our analyst  recommendations,
long-term  earnings  and  earnings  momentum,  which form the basis of  expected
future returns within any given sector.  These  expected  returns,  coupled with
detailed risk forecasts,  determine what holdings will be selected.  In building
and maintaining the Fund's portfolio,  we look to avoid a high risk-to-return on
its investments,  and carefully monitor sector  performance,  constantly looking
for any material changes and/or developments.

Thank you for  investing in the Smith Barney Sector  Series  Inc.--Smith  Barney
Health Sciences Fund. We look forward to helping you pursue your financial goals
in the years ahead.

Sincerely,

The Investment Team at
Citibank N.A.

NOVEMBER 7, 2000

    7 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS                                         OCTOBER 31, 2000
--------------------------------------------------------------------------------

     SHARES                          SECURITY                          VALUE
================================================================================

COMMON STOCK -- 100.0%

BIOTECHNOLOGY -- 16.1%
          4,774     Abgenix, Inc.+                                   $   376,549
          4,760     Affymetrix, Inc.+                                    263,585
          4,495     Alkermes, Inc.+                                      166,596
         35,836     Amgen, Inc.+                                       2,076,248
         13,328     Biochemical Pharmaceuticals, Inc.+                   329,868
          7,655     Biogen, Inc.+                                        460,735
          7,899     Chiron Corp.+                                        342,125
         23,700     Genentech Inc.+                                    1,955,250
          4,805     Genzyme Corp.+                                       341,155
          4,147     Gilead Sciences, Inc.+                               356,642
          6,186     Human Genome Sciences, Inc.+                         546,784
          2,838     Idec Pharmaceuticals Corp.+                          556,603
         24,126     Immunex Corp.+                                     1,026,863
          3,365     Maxygen, Inc.+                                       135,441
          4,252     Medarex, Inc.+                                       259,904
          9,336     Medimmune, Inc.+                                     610,341
          8,858     Millennium Pharmaceuticals+                          642,759
          2,704     PE Corp.-Celera+                                     182,520
          3,068     Protein Design Labs, Inc.+                           414,420
          4,950     Vertex Pharmaceuticals, Inc.+                        460,891
--------------------------------------------------------------------------------
                                                                      11,505,279
--------------------------------------------------------------------------------

GENERIC DRUGS -- 1.8%
          9,904     Ivax Corp.+                                          430,824
         16,752     Mylan Labs, Inc.                                     469,056
          6,378     Watson Pharmaceuticals, Inc.+                        399,024
--------------------------------------------------------------------------------
                                                                       1,298,904
--------------------------------------------------------------------------------

HOSPITAL NURSING MANAGEMENT -- 3.0%
         26,950     HCA Healthcare Corp.                               1,076,316
         22,676     Health Management Association+                       449,268
         14,761     Tenet Healthcare Corp.+                              580,292
--------------------------------------------------------------------------------
                                                                       2,105,876
--------------------------------------------------------------------------------

MAJOR PHARMACEUTICALS -- 50.5%
         72,812     Abbott Labs                                        3,845,384
         60,762     American Home Products Corp.                       3,858,387
         62,598     Brystol Myers-Squibb Co.                           3,814,566
         57,204     Eli Lilly & Co.                                    5,112,608
         47,609     Johnson & Johnson, Inc.                            4,385,979
         57,314     Merck & Co., Inc.                                  5,154,678
        109,788     Pfizer, Inc.                                       4,741,469
         42,479     Pharmacia & Upjohn Inc.                            2,336,345
         55,414     Schering-Plough Corp.                              2,864,211
--------------------------------------------------------------------------------
                                                                      36,113,627
--------------------------------------------------------------------------------

MANAGED HEALTH CARE -- 2.5%
          2,772     AETNA, Inc.                                          160,256
          5,697     Pacificare Health Systems+                            59,462
          9,627     UnitedHealth Group Inc.                            1,052,953
          4,444     Wellpoint Health Networks, Inc.+                     519,670
--------------------------------------------------------------------------------
                                                                       1,792,341
--------------------------------------------------------------------------------

                       SEE NOTES TO FINANCIAL STATEMENTS.

    8 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                             OCTOBER 31, 2000
--------------------------------------------------------------------------------

     SHARES                          SECURITY                          VALUE
================================================================================

MEDICAL/DENTAL DISTRIBUTORS-- 3.1%
          4,796     Andrx Corp.+                                     $   345,312
         15,031     Cardinal Health Inc.                               1,424,187
         16,954     McKesson HBOC, Inc.                                  475,772
--------------------------------------------------------------------------------
                                                                       2,245,271
--------------------------------------------------------------------------------

MEDICAL ELECTRONICS -- 4.9%
         64,354     Medtronic, Inc.                                    3,495,227
--------------------------------------------------------------------------------

MEDICAL SPECIALTIES -- 10.9%
          5,741     Alza Corp.+                                          464,662
          7,501     Bausch & Lomb                                        289,257
         21,067     Baxter International, Inc.                         1,731,444
         11,327     Becton Dickinson & Co.                               379,455
         12,186     Biomet, Inc.                                         440,981
         24,764     Boston Scientific Corp.+                             394,676
          6,849     C.R. Bard, Inc.                                      286,802
         21,226     Guidant Corp.+                                     1,123,651
         10,104     Hillenbrand Industries, Inc.                         467,310
          4,696     Minimed, Inc.+                                       342,515
          8,672     PE Corp.- PE Biosystems                            1,014,624
         10,938     Stryker Corp.                                        515,453
         14,539     Sybron International Corp.+                          359,840
--------------------------------------------------------------------------------
                                                                       7,810,670
--------------------------------------------------------------------------------

MULTI-LINE INSURANCE -- 1.5%
          9,032     Cigna Corp.                                        1,101,452
--------------------------------------------------------------------------------

PHARMACEUTICALS -- 3.5%
         11,339     Allergan, Inc.                                       953,185
          9,426     Biovail Corp.+                                       396,481
          4,239     Forest Labs, Inc.+                                   561,668
          7,985     King Pharmaceuticals Inc.+                           357,828
          3,708     Sepracor, Inc.+                                      252,607
--------------------------------------------------------------------------------
                                                                       2,521,769
--------------------------------------------------------------------------------

PRECISION INSTRUMENTS -- 0.8%
          5,700     Visx Inc.+                                           122,194
          6,002     Waters Corp.+                                        435,520
--------------------------------------------------------------------------------
                                                                         557,714
--------------------------------------------------------------------------------

SERVICES TO THE HEALTH INDUSTRY -- 1.4%
            939     Cybear Group+                                            646
         20,360     IMS Health, Inc.                                     481,005
          3,488     Quest Diagnostics, Inc.+                             335,720
         12,468     Quintiles Transnational Corp.+                       173,773
            893     Synavant Inc.+                                         4,074
--------------------------------------------------------------------------------
                                                                         995,218
--------------------------------------------------------------------------------
                    TOTAL COMMON STOCK -- 100%
                    (Identified Cost -- $61,246,533)*                $71,543,348
================================================================================
+ NON-INCOME PRODUCING SECURITY.
* AGGREGATE COST FOR FEDERAL INCOME TAXES IS SUBSTANTIALLY THE SAME.

                       SEE NOTES TO FINANCIAL STATEMENTS.

    9 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF ASSETS AND LIABILITIES                            OCTOBER 31, 2000
--------------------------------------------------------------------------------

ASSETS:
     Investments, at value (Cost -- $61,246,533)                   $ 71,543,348
     Receivable for Investments sold                                    777,391
     Receivable for Fund shares sold                                    406,667
     Dividends and interest receivable                                   37,654
--------------------------------------------------------------------------------
     TOTAL ASSETS                                                    72,765,060
--------------------------------------------------------------------------------

LIABILITIES:
     Payable for securities purchased                                   173,198
     Payable for Fund shares purchased                                    6,695
     Payable to custodian                                               459,008
     Distribution fees payable                                           48,039
     Management fees payable                                             17,334
     Accrued expenses and other liabilities                             114,809
--------------------------------------------------------------------------------
     TOTAL LIABILITIES                                                  819,083
--------------------------------------------------------------------------------

TOTAL NET ASSETS                                                    $71,945,977
================================================================================

NET ASSETS:
     Par value of capital shares                                    $     4,983
     Capital paid in excess of par value                             60,052,633
     Accumulated net investment loss                                     (7,876)
     Accumulated net realized gain from security transactions         1,599,422
     Net unrealized appreciation of investments                      10,296,815
--------------------------------------------------------------------------------

TOTAL NET ASSETS                                                    $71,945,977
================================================================================

SHARES OUTSTANDING:
     Class A                                                          1,171,551
     ---------------------------------------------------------------------------
     Class B                                                          1,989,567
     ---------------------------------------------------------------------------
     Class L                                                          1,821,685
     ---------------------------------------------------------------------------

NET ASSET VALUE:

     Class A (and redemption price)                                      $14.49
     ---------------------------------------------------------------------------
     Class B *                                                           $14.42
     ---------------------------------------------------------------------------
     Class L **                                                          $14.42
     ---------------------------------------------------------------------------

MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
     Class A (net asset value plus 5.26% of net asset value per share)   $15.25
     ---------------------------------------------------------------------------
     Class L (net asset value plus 1.01% of net asset value per share)   $14.57
================================================================================

*  REDEMPTION  PRICE IS NAV OF CLASS B SHARES  REDUCED BY A 5.00% CDSC IF SHARES
   ARE REDEEMED LESS THAN ONE YEAR FROM INITIAL PURCHASE (SEE NOTE 2).
** REDEMPTION  PRICE IS NAV OF CLASS L SHARES  REDUCED BY A 1.00% CDSC IF SHARES
   ARE REDEEMED WITHIN THE FIRST YEAR OF PURCHASE.

                       SEE NOTES TO FINANCIAL STATEMENTS.

    10 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF OPERATIONS
--------------------------------------------------------------------------------

FOR THE PERIOD FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

INVESTMENT INCOME:
     Dividends                                                      $   239,295
     Interest                                                            37,686
--------------------------------------------------------------------------------
     TOTAL INVESTMENT INCOME                                            276,981
--------------------------------------------------------------------------------

EXPENSES:
     Distribution fees (Note 2)                                         268,921
     Management fees (Note 2)                                           261,782
     Custody fees                                                       133,141
     Shareholder communications                                          39,293
     Legal fees                                                          34,472
     Registration fees                                                   20,370
     Audit fees                                                          17,667
     Directors' fees                                                      7,727
     Other                                                               37,713
--------------------------------------------------------------------------------
     TOTAL EXPENSES                                                     821,086
     Less: Aggregate amount waived by the Manager (Note 2)             (136,709)
--------------------------------------------------------------------------------
     NET EXPENSES                                                       684,377
--------------------------------------------------------------------------------
NET INVESTMENT LOSS                                                    (407,396)
--------------------------------------------------------------------------------

REALIZED AND UNREALIZED GAIN ON INVESTMENTS (NOTE 3):
     Realized Gain From:
        Security transactions (excluding short-term securities)       1,930,048
--------------------------------------------------------------------------------
     Increase in Net Unrealized Appreciation                         10,296,815
--------------------------------------------------------------------------------
NET GAIN ON INVESTMENTS                                              12,226,863
--------------------------------------------------------------------------------
INCREASE IN NET ASSETS FROM OPERATIONS                              $11,819,467
================================================================================





                       SEE NOTES TO FINANCIAL STATEMENTS.

    11 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------

FOR THE PERIOD FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

OPERATIONS:
     Net investment loss                                            $  (407,396)
     Net realized gain                                                1,930,048
     Increase in net unrealized appreciation                         10,296,815
--------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM OPERATIONS                          11,819,467
--------------------------------------------------------------------------------

FUND SHARE TRANSACTIONS (NOTE 6):
     Net proceeds from sale of shares                                70,184,936
     Net asset value of shares issued for reinvestment of dividends          --
     Cost of shares reacquired                                      (10,058,426)
--------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS             60,126,510
--------------------------------------------------------------------------------

INCREASE IN NET ASSETS                                               71,945,977

NET ASSETS:
     Beginning of period                                                     --
--------------------------------------------------------------------------------
     END OF PERIOD*                                                 $71,945,977
================================================================================
* Includes accumulated net investment loss of:                      $    (7,876)
================================================================================



                       SEE NOTES TO FINANCIAL STATEMENTS.

    12 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1. Significant Accounting Policies

The Smith Barney Health  Sciences Fund is a  non-diversified  investment fund of
the Smith  Barney  Series Inc.  (the  "Company"),  a Maryland  corporation.  The
Company is registered under the Investment  Company Act of 1940, as amended,  as
an open-end  management  investment  company and  consists of this Fund and five
other separate  investment  funds:  Smith Barney Financial  Services Fund, Smith
Barney  Technology  Fund, Smith Barney Global  Biotechnology  Fund, Smith Barney
Global Media & Telecommunications  Fund and Smith Barney Global Technology Fund.
On February 28, 2000 the Fund commenced operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed to be  over-the-counter)  and securities for which no sale was reported
on that date are valued at the mean  between the bid and ask prices.  Securities
which are listed or traded on more than one exchange or market are valued at the
quotations  on the exchange or market  determined  to be the primary  market for
such  securities;  (c) securities for which market  quotations are not available
will be valued in good faith at fair market  value by or under the  direction of
the Board of Directors;  (d)  securities  maturing  within 60 days are valued at
cost plus accreted  discount,  or minus amortized  premium,  which  approximates
value;  (e) the accounting  records of the Fund are maintained in U.S.  dollars.
All assets and liabilities denominated in foreign currencies are translated into
U.S.  dollars  based on the rate of exchange  of such  currencies  against  U.S.
dollars on the date of valuation.  Purchases and sales of securities, and income
and expenses are  translated  at the rate of exchange  quoted on the  respective
date that such transactions are recorded.  Differences between income or expense
amounts  recorded  and  collected  or paid are  adjusted  when  reported  by the
custodian;  (f)  interest  income,  adjusted  for  amortization  or premium  and
accretion of discount,  is recorded on an accrual basis;  (g) dividend income is
recorded  on  the  ex-dividend  date;  foreign  dividends  are  recorded  on the
ex-dividend date or as soon as practical after the Fund determines the existence
of a  dividend  declaration  after  exercising  reasonable  due  diligence;  (h)
dividends and  distributions  to  shareholders  are recorded on the  ex-dividend
date;  (i) gains or losses on the sale of securities are calculated by using the
specific  indentification method; (j) direct expenses are charged to each class;
management fees and general  expenses are allocated on the basis of relative net
assets;  (k) the character of income and gains to be distributed  are determined
in  accordance  with  income tax  regulations  which may differ  from  generally
accepted  accounting  principles;  (l) the  Fund  intends  to  comply  with  the
requirements  of the Internal  Revenue Code of 1986,  as amended,  pertaining to
regulated  investment  companies  and to make  distributions  of taxable  income
sufficient to relieve it from substantially all Federal income and excise taxes;
(m) the  character  of income and gains to be  distributed  in  accordance  with
income tax  regulations  which may differ  from  generally  accepted  accounting
principles.  At  October  31,  2000,  reclassifications  were made to the Funds'
capital accounts to reflect permanent book/tax  differences and income and gains
available for distribution under income tax regulations.  Accordingly,  the Fund
reclassified  $399,520 to accumulated net investment loss,  $68,894 from paid in
capital and $330,626 from accumulated net realized gain. Net investment  income,
net realized gains and net assets were not affected by this adjustment;  and (n)
estimates and assumptions are required to be made regarding assets,  liabilities
and changes in net assets  resulting from operations  when financial  statements
are prepared.  Changes in the economic  environment,  financial  markets and any
other parameters used in determining  these estimates could cause actual results
to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market rate as an unrealized respectively.

    13 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

2. Management Agreement and Other Transactions

SSB Citi Fund  Management  LLC  ("SSBC"),  a subsidiary  of Salomon Smith Barney
Holdings  Inc.  ("SSBH"),  which,  in turn,  is a subsidiary  of Citigroup  Inc.
("Citigroup"),  acts as investment  manager to the Fund.  The  management fee is
computed at an annual rate of 0.80% of the  average  daily net assets.  SSBC has
delegated  the  daily  management  of  the  Portfolio  to  Citibank  N.A.,  (the
"SubAdviser"),  an affiliate of SSBC.  For  services  provided to the Fund,  the
manager  pays the  Subadviser  a  subadvisory  fee computed at an annual rate of
0.50% of the Fund's average daily net assets.  The management fees paid amounted
to $261,782, of which $136,709 was waived for the period ended October 31, 2000.

Salomon  Smith Barney Inc.  ("SSB"),  another  subsidiary  of SSBH,  acts as the
Fund's distributor,  as well as certain other broker-dealers,  continues to sell
Fund shares to the public as a member of the selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and PFPC Global Fund  Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTC receives fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $23,837 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
================================================================================
CDSCs                       $  2,000       $19,000     $  8,000
--------------------------------------------------------------------------------
Sales Charges               $255,000       $78,000     $224,000
================================================================================

Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
================================================================================
Distribution Plan Fees       $19,436      $130,323     $119,162
================================================================================

All officers and one Director of the Fund are employees of SSB.

3. Investments

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

================================================================================
Purchases                                           $72,980,921
--------------------------------------------------------------------------------
Sales                                               $13,664,436
================================================================================

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

================================================================================
Gross unrealized appreciation                       $12,115,428
Gross unrealized depreciation                        (1,818,613)
--------------------------------------------------------------------------------
Net unrealized appreciation                         $10,296,815
================================================================================


4. Repurchase Agreements

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Fund requires continual  maintenance
of the market  value of the  collateral  (plus  accrued  interest) in amounts at
least equal to the repurchase price.

    14 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

5. Concentration of Risk

The  Fund  normally  invests  at  least  80% of its  assets  in  health  related
investments.  As a result of this concentration  policy,  which is a fundamental
policy of the Fund,  the Fund's  investments  may be subject to greater risk and
market fluctuation than a fund that invests in securities representing a broader
range of investment alternatives.

The Fund's  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S. dollar can  significantly  affect the value of these investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.

6. Capital Shares

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.

At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:

                             CLASS A       CLASS B       CLASS L
================================================================================
Total Paid-in Capital      $14,146,564   $24,017,482   $21,962,464
================================================================================





Transactions in shares of each class were as follows:

                                                       FEBRUARY 28, 2000
                                                 (COMMENCEMENT OF OPERATIONS)
                                                      TO OCTOBER 31, 2000
                                              --------------------------------
                                                 SHARES               AMOUNT
================================================================================
CLASS A
Shares sold                                    1,584,698            $19,845,221
Shares issued on reinvestment                         --                     --
Shares reacquired                               (413,147)            (5,698,657)
--------------------------------------------------------------------------------
Net Increase                                   1,171,551            $14,146,564
================================================================================
CLASS B
Shares sold                                    2,172,669            $26,437,205
Shares issued on reinvestment                         --                     --
Shares reacquired                               (183,102)            (2,419,723)
--------------------------------------------------------------------------------
Net Increase                                   1,989,567            $24,017,482
================================================================================
CLASS L
Shares sold                                    1,967,825            $23,902,509
Shares issued on reinvestment                         --                     --
Shares reacquired                               (146,140)            (1,940,045)
--------------------------------------------------------------------------------
Net Increase                                   1,821,685            $21,962,464
================================================================================




    15 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS A SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                (0.04)
   Net realized and unrealized gain                    3.13
--------------------------------------------------------------------------------
Total Income From Operations                           3.09
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                 --
   Net realized gain                                     --
--------------------------------------------------------------------------------
Total Distributions                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                       $14.49
--------------------------------------------------------------------------------
TOTAL RETURN                                          27.11%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                    $16,980
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                            1.52%+
   Net investment loss                                (0.67)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                  26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT  INCOME (LOSS) PER SHARE AND THE RATIOS WOULD HAVE BEEN
      AS FOLLOWS:

   Net investment loss per share                     $(0.04)
   RATIOS:
   Expenses to average net assets                      1.94%+
   Net investment loss to average net assets          (1.09)%+
================================================================================

+  ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED,  AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.

    16 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS B SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                (0.09)
   Net realized and unrealized gain                    3.11
--------------------------------------------------------------------------------
Total Income From Operations                           3.02
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                 --
   Net realized gain                                     --
--------------------------------------------------------------------------------
Total Distributions                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                       $14.42
--------------------------------------------------------------------------------
TOTAL RETURN                                          26.49%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                    $28,694
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                            2.26%+
   Net investment loss                                (1.41)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                  26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET  INVESTMENT  LOSS PER  SHARE  AND THE  RATIOS  WOULD  HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                  $(0.10)
      RATIOS:
      Expenses to average net assets                   2.68%+
      Net investment loss to average net assets       (1.83)%+
================================================================================
+  ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED,  AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.

    17 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK, FROM FEBRUARY 28, 2000 (COMMENCEMENT
OF OPERATIONS) TO OCTOBER 31, 2000

CLASS L SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                (0.09)
   Net realized and unrealized gain                    3.11
--------------------------------------------------------------------------------
Total Income From Operations                           3.02
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                 --
   Net realized gain                                     --
--------------------------------------------------------------------------------
Total Distributions                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                       $14.42
--------------------------------------------------------------------------------
TOTAL RETURN                                          26.49%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                    $26,273
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                            2.27%+
   Net investment loss                                (1.42)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                  26%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET  INVESTMENT  LOSS PER  SHARE  AND THE  RATIOS  WOULD  HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                  $(0.10)
      RATIOS:
      Expenses to average net assets                   2.68%+
      Net investment loss to average net assets       (1.83)%+
================================================================================

+  ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED,  AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.

    18 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
INDEPENDENT AUDITORS' REPORT
--------------------------------------------------------------------------------

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTOR SERIESINC.:

We have audited the accompanying statement of assets and liabilities,  including
the schedule of  investments,  of Smith  Barney  Health  Sciences  Fund of Smith
Barney  Sector  Series Inc. as of October 31, 2000,  the related  statements  of
operations, the statements of changes in net assets and financial highlights for
the period February 28, 2000  (Commencement  of Operations)  through October 31,
2000. These financial statements and financial highlights are the responsibility
of the Fund's  management.  Our responsibility is to express an opinion on these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney Health Sciences Fund of Smith Barney Sector Series Inc. as of October 31,
2000, the results of its operations, the changes in its net assets and financial
highlights  for the period  February  28,  2000  through  October 31,  2000,  in
conformity with accounting principles generally accepted in the United States of
America.

/s/ KMPG LLP
------------

New York, New York
December 11, 2000



    19 SMITH BARNEY HEALTH SCIENCES FUND | 2000 Annual Report to Shareholders
<PAGE>










                      (This page intentionally left blank.)







<PAGE>

SMITH BARNEY
HEALTH SCIENCES FUND

    DIRECTORS                                 INVESTMENT MANAGER
    Herbert Barg                              SSBCiti Fund Management LLC
    Alfred J. Bianchetti
    Martin Brody                              INVESTMENT SUBADVISER
    Dwight B. Crane                           Citibank, N.A.
    Burt N. Dorsett
    Elliot S. Jaffe                           DISTRIBUTORS
    Stephen E. Kaufman                        Salomon Smith Barney, Inc.
    Joseph J. McCann                          PFS Distributors Inc.
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.                    CUSTODIAN
    James J. Crisona, Emeritus                State Street Bank & Trust Co.

                                              TRANSFER AGENT
    OFFICERS                                  Citi Fiduciary Trust Company
    Heath B. McLendon                         125 Broad Street, 11th Floor
    President and Chief Executive Officer     New York, New York 10004

                                              SUB-TRANSFER AGENT
    Lewis E. Daidone                          PFPC Global Fund Services
    Senior Vice President and Treasurer       P.O. Box 9699
                                              Providence, Rhode Island
                                              02940-9699
    Irving P. David
    Controller


    Christina T. Sydor
    Secretary
<PAGE>

SMITH BARNEY HEALTH SCIENCES FUND
================================================================================

This report is submitted for general information of the shareholders of Smith
Barney Sector Series Inc. -- Smith Barney Health Sciences Fund, but it may also
be used as sales literature when preceded or accompanied by the current
Prospectus, which gives details about charges, expenses, investment objectives
and operating policies of the Fund. If used as sales material after January 31,
2001, this report must be accompanied by performance information for the most
recently completed calendar quarter.

SMITH BARNEY HEALTH SCIENCES FUND
Smith Barney Mutual Funds
388 Greenwich Street, MF-2
New York, New York 10013


For complete information on any Smith Barney Mutual Funds, including management
fees and expenses, call or write your financial professional for a free
prospectus. Read it carefully before you invest or send money.

www.smithbarney.com/mutualfunds


[SALOMON SMITH BARNEY LOGO]

Salomon Smith Barney is a service mark of Salomon Smith Barney Inc.

FD02128 12/00

<PAGE>
--------------------------------------------------------------------------------
                                  SMITH BARNEY
                               SECTOR SERIES INC.
                                 TECHNOLOGY FUND
-------------------------------------------------------------------------------

               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000


[LOGO OMITTED]   SMITH BARNEY MUTUAL FUNDS
                 YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED. (SM)


-------------------------------------------------------------------------------
             NOT FDIC INSURED O NOT BANK GUARANTEED O MAY LOSE VALUE
-------------------------------------------------------------------------------

<PAGE>

[GRAPHIC] Research Series

Annual Report o October 31, 2000

SMITH BARNEY
TECHNOLOGY FUND

CITIBANK GLOBAL ASSET MANAGEMENT

Citibank,  N.A.,  through its Citibank Global Asset  Management  division is the
subadviser to the Fund.  Comprising a seasoned  group of investment and research
professionals,  the Fund's  management  team follows a  systematic  and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks long-term capital  appreciation by investing  primarily in common
stocks.  The Fund invests at least 80% of its assets in  securities of companies
principally  engaged in offering,  using or  developing  products,  processes or
services  that will provide or will  benefit  significantly  from  technological
advances and improvements.

FUND FACTS

FUND INCEPTION
--------------------------------------------------------------------------------
February 28, 2000

           CLASS A     CLASS B     CLASS L
--------------------------------------------------------------------------------
NASDAQ     SBTAX        SBTBX      SBQLX
--------------------------------------------------------------------------------
INCEPTION  2/28/00    2/28/00     2/28/00
--------------------------------------------------------------------------------

Smith Barney Technology Fund*
Total Returns October 31, 2000

                      WITHOUT SALES CHARGES(1)
                  Class A     Class  B   Class L
--------------------------------------------------------------------------------

Since Inception+  (19.82)%    (20.26)%   (20.26)%
(February 28, 2000)**
--------------------------------------------------------------------------------


                        WITH SALES CHARGES(2)
                  Class A     Class  B   Class L
--------------------------------------------------------------------------------

Since Inception+  (23.83)%    (24.25)%   (21.85)%
(February 28, 2000)**
--------------------------------------------------------------------------------



* Since the Fund focuses its investments on companies involved in the technology
  industries,  an  investment  in the Fund may involve a greater  degree of risk
  than an investment in other mutual funds with greater diversification

**Not Annualized

(1)  Assumes  reinvestment of all dividends and capital gain  distributions,  if
     any, at net asset value and does not reflect  deduction  of all  applicable
     sales  charges  with  respect  to  Class A and L shares  or the  applicable
     contingent  deferred  sales charges  ("CDSC") with respect to Class B and L
     shares.

(2)  Assumes  reinvestment of all dividends and capital gain  distributions,  if
     any at net asset  value.  In  addition,  Class A and L shares  reflect  the
     deduction  of  the  maximum  initial  sales  charge  of  5.00%  and  1.00%,
     respectively.  Class B shares reflect the deduction of a 5.00% CDSC,  which
     applies if shares are  redeemed  within one year from  purchase.  This CDSC
     declines by 1.00% the first year after purchase and thereafter by 1.00% per
     year until no CDSC is incurred.  Class L shares also reflect the  deduction
     of 1.00% per year until CDSC,  which applies if shares are redeemed  within
     the first year of purchase.


WHAT'S INSIDE
Your Investment in the Smith Barney Technology Fund .....  1
Letter from the Chairman ................................  2
Fund at a Glance ........................................  3
Shareholder Letter ......................................  4
Schedule of Investments .................................  8
Statement of Assets and Liabilities ..................... 11
Statement of Operations ................................. 12
Statement of Changes in Net Assets ...................... 13
Notes to Financial Statements ........................... 14
Financial Highlights .................................... 17
Independent Auditors' Report ............................ 20

[LOGO]  SMITH BARNEY MUTUAL FUNDS
        YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)

-------------------------------------------------------------------------------
  INVESTMENT PRODUCTS: NOT FDIC INSURED O NOT BANK GUARANTEED O MAY LOSE VALUE
-------------------------------------------------------------------------------



<PAGE>


-------------------------------------------------------------------------------
               YOUR INVESTMENT IN THE SMITH BARNEY TECHNOLOGY FUND
-------------------------------------------------------------------------------


Led by Citibank N.A. through Citibank Global Asset Management ("CGAM") division,
the Fund offers investors the opportunity to participate in the long-term growth
potential of the technology  industry.  The Fund's  management  team comprises a
seasoned group of investment and research  professionals who follow a systematic
and rigorous  approach designed to provide  appropriate  exposure to each market
sector.

[GRAPHIC OMITTED]
     BRINGING CHANGE AND INNOVATION TO LIFE

     Innovation  is rapidly  transforming  the way we live and do  business on a
     global  scale.  Spending  on  technology  has  consistently   increased  as
     consumers and businesses  are  recognizing  technology's  important role in
     today's global economy. This increased spending has in turn caused the role
     of technology to expand.

[GRAPHIC OMITTED]
     DIVERSIFICATION IN A TARGETED SECTOR*

     An  investment  in the Fund  offers  investors a way to invest in the broad
     range of  technology  companies  both in the U.S.  and  abroad.  The Fund's
     investments  may include  companies in a wide range of  industries  such as
     computer software, electronics, the Internet and communications.

[GRAPHIC OMITTED]
     THE BENEFITS OF EXHAUSTIVE  FUNDAMENTAL  SECURITIES  ANALYSIS--THE RESEARCH
     SERIES

     The Research  Series is a selection of Smith Barney Mutual Funds built on a
     foundation of  substantial  buy-side  research under the direction of CGAM.
     This series of funds focuses on potential  opportunities  from well-defined
     industries, sectors and trends.

[GRAPHIC OMITTED]
     A COMMITMENT TO MANAGING YOUR SERIOUS MONEY

     SSB Citi Asset  Management  Group ("SSB Citi"),  the investment  management
     division of Citigroup,  comprises  Smith Barney Asset  Management,  Salomon
     Brothers Asset  Management and Citibank  Global Asset  Management,  each an
     organization with extensive investment capabilities.

     SSB Citi, as a member of one of the largest financial services providers in
     the world, offers you the benefits of our global capabilities. At SSB Citi,
     you gain access to portfolio  management delivered  professionally.  We are
     proud to offer you, the serious investor, a variety of managed solutions.





*Please note that because the Fund invests in a single  industry,  its shares do
 not  represent  a complete  investment  program and the value of its shares may
 fluctuate more than shares invested in a broader range of industries.

       1 Smith Barney Technology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
                            LETTER FROM THE CHAIRMAN
-------------------------------------------------------------------------------



The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks may be running  out of steam.  At SSB Citi Asset
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.

We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their  businesses.  Today,  with over $398.6 billion in assets under management,
(1) SSB Citi offers choices and solutions,  uniting the distinguished history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.

A FEW THOUGHTS ON SECTOR INVESTING
Over the past few years,  we have seen how profoundly the  advancements  made in
sectors such as technology and  telecommunications  have  transformed  our daily
lives.  Computer  applications,  wireless  communications  and  biotechnological
discoveries  have created new investment  opportunities.  The new and developing
sectors of the economy that are involved in bringing  these  products,  services
and  technologies  to life may  offer  exceptional  growth  potential,  and many
investors  should  consider having a portion of their  investment  portfolios in
them.

Although most of us recognize that certain sectors drive the economy, we believe
it is much more  difficult  to  determine  which  companies  within a particular
sector will perform  better than the others over time.  The team of  experienced
professionals at Citibank N.A. thoroughly  researches a broad range of companies
within a given sector and carefully  analyzes  them,  looking to identify  those
companies  that they believe offer the greatest  growth  potential over the long
term. Through this exhaustive and proprietary  process,  CGAM seeks to offer you
an  opportunity  to  participate  in  those   companies  that  it  believes  are
best-positioned in their respective industries.

[PHOTO OMITTED]
HEATH B. MCLENDON
CHAIRMAN

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.

When you  invest  with SSB  Citi,  you can do so with the  confidence  that your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.

Thank you for your confidence in our investment management approach.


Sincerely,



/s/ Heath B. McLendon
---------------------

HEATH B. MCLENDON
CHAIRMAN

November 6, 2000


--------------------

(1)  As of October 31, 2000. This figure represents retail, institutional, money
     and separate accounts.

       2 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY TECHNOLOGY FUND AT A GLANCE (UNAUDITED)
--------------------------------------------------------------------------------

GROWTH OF $10,000 INVESTED IN THE
SMITH BARNEY TECHNOLOGY FUND VS. GOLDMAN SACHS TECHNOLOGY INDEX
--------------------------------------------------------------------------------
       February 28, 2000 (Commencement of Operations) -- October 31, 2000

[The following table represents a line graph in printed piece.]

           Smith Barney
          Technology Fund    Goldman Sachs
             Class A       Technology Index*
2/28/00        9500            10000
2/29/00        9683.33         10000
3/31/00        10041.7         10449
4/28/00        9316.67          9537.85
5/31/00        8241.67          8486.78
6/30/00        9233.33          9530.65
7/31/00        8783.33          9086.52
8/31/00        9916.67         10268.7
9/30/00        8216.67          8605.15
10/31/00       7616.67          7955.46


A $10,000  investment  in the Fund made on February 28, 2000 would have declined
to $7,617 with sales  charge (as of October 31,  2000).  The graph shows how the
Fund  compares to its  benchmark  for the same  period.  The graph  includes the
initial sales charge on the Fund (no comparable charge exists for the index) and
assumes all dividends and distributions are reinvested at Net Asset Value

*    The  Goldman  Sachs  Technology  Index is  comprised  of  companies  in the
     hardware,  computer,  software,  services,  semi-conductors,  Internet  and
     multimedia networking.  Please note that an investor cannot invest directly
     in an index.The  Nasdaq  Composite Index is a market  value-weighted  index
     that  measures all domestic and  non-U.S.  based  securities  listed on the
     NASDAQ stock market.

--------------------------------------------------------------------------------
                         TOP TEN COMMON STOCK HOLDINGS*
--------------------------------------------------------------------------------

1. Cisco Systems Inc. ...................     8.9%

2. Microsoft Corp. ......................     8.5

3. Intel Corp. ..........................     5.8

4. EMC Corp. ............................     4.8

5. International Business Machines Corp..     4.7

6. Sun Microsystems Inc. ................     4.4

7. Oracle Corp. .........................     3.9

8. Nortel Networks Corp. ................     3.2

9. America Online Inc. ..................     2.9

10. Hewlett-Packard Co. .................     2.4

* As a percentage of total investments.

-------------------------------------------------------------------------------
                              PORTFOLIO BREAKDOWN*
-------------------------------------------------------------------------------
[The following table represents a pie chart in the printed piece.]

 0.5%    Other Consumer Services
 0.6%    Discount Note
 0.6%    Electronic Components
 0.7%    Catalog/Specialty Distributions
 0.9%    Diversified Commercial Services
 1.3%    Diversified Electronic Products
 2.4%    EDP Services
 3.7%    Electronic Production Equipment
 6.6%    EDP Peripherals
 8.1%    Internet Services
10.8%    Computer Communications
12.1%    Telecommunications Equipment
16.1%    Electronic Data Processing
16.8%    Semiconductors
18.8%    Computer Software
-------------------------------------------------------------------------------

       3 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

Dear Shareholder:

We are pleased to provide the annual  report for the Smith Barney  Sector Series
Inc.--Smith Barney Technology Fund ("Fund") for the year ended October 31, 2000.
In this report we have  summarized the period's  prevailing  economic and market
conditions and outlined our investment  strategy.  The  information  provided in
this letter  represents  the opinion of the manager and is not  intended to be a
forecast of future events, a guarantee of future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 10 for a complete list and percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE
Since the Fund's  inception on February 28, 2000 through  October 31, 2000,  the
Fund's  Class A,  shares,  without and with sales  charges,  generated  negative
returns of 19.82% and 23.83%,  respectively.  In  comparison,  the Goldman Sachs
Technology  Index(1) returned a negative  20.45% for the same time  period. Past
performance is not indicative of future results.

SECTOR INVESTING--THE CGAM PROCESS
Our  approach  to  sector  investing  is based on  exhaustive  research  that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive industry expertise.  Our team looks for analytical consistency through
intensive modeling and strict application of a consistent valuation methodology.

Our management team is made up of a group of high-quality,  seasoned  investment
and  research  professionals  who  follow a  systematic  and  rigorous  strategy
designed  to  provide  the right  exposure  to  various  industries  within  any
particular sector they cover. Our exhaustive  fundamental  research  evaluates a
universe of businesses in our global quest to identify and  participate  in what
we deem attractive investment opportunities.

A THREE-STEP RESEARCH PROCESS

-------------------------------------------------------------------------------
         FUNDAMENTAL --------> QUANTITATIVE --------> ACTIVE PORTFOLIO
          RESEARCH               RESEARCH                MANAGEMENT
-------------------------------------------------------------------------------

We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to  create  portfolios  that we think  should  generate  competitive
returns while helping to moderate risk over time.

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)



------------
(1)  The Goldman Sachs Technology Index is a broad-based  measure of U.S.-traded
     technology  stocks.  The Index is  comprised  of six  subindexes--hardware,
     computer  software,  services,  semi-conductors,  Internet  and  multimedia
     networking.  Please  note that an  investor  cannot  invest  directly in an
     index.



       4 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

-------------------------------------------------------------------------------
                        LEADING SEGMENT OF U.S. ECONOMY--
        INCREASED DEMAND HAS PROPELLED TECHNOLOGY TO BECOME A BIGGER PART
                               OF TODAY'S ECONOMY.
        AS THE GLOBAL ECONOMY CONTINUES TO EMBRACE TECHNOLOGY, WE BELIEVE
                      THIS MARKET SECTOR MAY CONTINUE TO BE
                               A DOMINANT PLAYER.
--------------------------------------------------------------------------------

Our  fundamental,  proprietary  research  can  add  value  to  active  portfolio
management by providing timely and unbiased information to their decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

o Superior products or services
o Outstanding managements
o Solid balance sheets
o Market leadership
o Leading innovation

In our opinion,  these are the companies'  strengths that can potentially create
real value and lead to strong earnings and sales growth, which ultimately drives
stock prices.

--------------------------------------------------------------------------------
                         INCREASED DEMAND FOR TECHNOLOGY
                       IN 1999 AS BUSINESS SPENT CLOSE TO
                           $550 BILLION ON TECHNOLOGY,
                     DOUBLE THE AMOUNT SPENT IN EARLY 1995.
                       SOURCE: U.S DEPARTMENT OF COMMERCE
--------------------------------------------------------------------------------

THE CGAM RESEARCH PROCESS DEFINED

We look to  differentiate  ourself from the  traditional  approach to investment
management in a number of ways that we can add value to our clients' portfolios.
Our management  style can best be described as  disciplined,  yet flexible.  Our
formidable  global reach and local expertise enable us to nurture research teams
with direct  access to the regions and  industries  where they do business.  Our
research  organization  is centered on a team  approach  to stock  research  and
selection by covering  hundreds of companies and working  closely  together both
within  and  across  industry  teams in a  seamless  fashion  to reach a prudent
consensus.


       5 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>


Each stock analyst builds intensive,  detailed company models from the ground up
that anticipate a particular company's financial  performance.  These models are
based on the company's  competitive  position  within the  industry,  quality of
product offerings,  costs and risks. These intensive models detail the analyst's
assumptions  for  potential  profitability  for the  company  going  forward and
provide some of the necessary  information to forecast company  fundamentals and
make stock  recommendations.  Our research team looks to ensure  consistency  in
industry  and  accounting  assumptions  and that in turn can  allow  for  better
comparisons of earnings forecasts.

--------------------------------------------------------------------------------
                      EACH CGAM ANALYST BUILDS INTENSIVE,
                    DETAILED COMPANY MODELS FROM THE GROUND
                    UP THAT SEEK TO ANTICIPATE A PARTICULAR
                    COMPANY'S FUTURE FINANCIAL PERFORMANCE.
--------------------------------------------------------------------------------

A common  valuation  framework--based  on the Dividend  Discount  Model  ("DDM")
allows for estimation of returns to fair value.  Simply stated, the DDM compares
a company's future discounted dividend stream to its current stock price.

We  believe  this  is a  valuable  and  consistent  method  to  provide  current
valuations  to  securities.  The  DDM-based  valuation  process,  in their view,
provides a common  yardstick that helps analysts and portfolio  managers compare
the relative  valuation of one company's  stock to another.  The equity  analyst
then combines the DDM valuation together with other fundamental factors, such as
earnings surprises, to come up with an investment rating on a company's stock.

TECHNOLOGY SECTOR UPDATE

Despite good earnings from industry bellweathers such as Sun Microsystems,  EMC,
Veritas and  Microsoft,  negative  investor  sentiment  continued in technology,
particularly with  weaker-than-expected  revenue growth from Nortel Networks. We
think concerns regarding slowing capital spending on the part of telecom service
providers,  along with continued  financing  fallout from less  well-capitalized
firms in this space,  have also contributed to the intensity of investor anxiety
regarding the outlook for equipment providers.

It is our view that the current  correction in stock valuations  rolling through
the sector has resulted in a healthier, more rational  environment--namely,  one
in which stock selection may become increasingly  important and favorable to our
bottom-up, fundamentals-focused,  disciplined approach to investing. We continue
to believe  technology is an attractive source of investment  opportunities with
solid, long-term growth prospects and good underlying fundamentals.

The  Fund  is  presently  slightly  overweight  in  hardware  companies  such as
International  Business  Machines  ("IBM")  and  semiconductor  equipment  maker
Applied Material Inc., while slightly underweight in network equipment providers
and Internet  companies  versus the benchmark.  While the Fund is underweight in
software,  we maintain a positive  outlook on J.D.  Edwards & Co., a provider of
business productivity software. The company has recently been eliminating excess
sales costs, yet has still maintained a good backlog of pipeline business.


       6 Smith Barney Technology Fund | 2000 Annual Report to Shareholders


<PAGE>

Although we look to identify those companies held in the Fund through  bottom-up
fundamental research and stock selection, its overall industry mix is consistent
with the top-down strategic industry themes that we use for estimate forecasting
and rating  formulation.  Since industries within technology are generally quick
to innovate and consolidate, we carefully monitor the Fund's holdings to reflect
any changes that may have an impact on performance.

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT

The management of the Fund is driven by our analyst  recommendations,  long-term
earnings and earnings momentum,  which form the basis of expected future returns
within any given  sector.  These  expected  returns,  coupled with detailed risk
forecasts, determine what holdings will be selected. In building and maintaining
the Fund's portfolio, we look to avoid a high risk-to-return on its investments,
and carefully monitor sector  performance,  constantly  looking for any material
changes and/or developments.

Thank you for  investing in the Smith Barney Sector  Series  Inc.--Smith  Barney
Technology  Fund. We look forward to helping you pursue your financial  goals in
the years ahead.

Sincerely,

The Investment Team at
Citibank N.A.

November 7, 2000


       7 Smith Barney Technology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS                                        OCTOBER 31, 2000
-------------------------------------------------------------------------------
     SHARES                         SECURITY                           VALUE
-------------------------------------------------------------------------------
COMMON STOCK -- 99.4%
CATALOG/SPECIALTY DISTRIBUTION -- 0.7%
         33,934     Amazon.com, Inc. +                              $1,242,833
-------------------------------------------------------------------------------
COMPUTER COMMUNICATIONS -- 10.8%
        305,923     Cisco Systems Inc. +                            16,481,602
         12,900     Computer Sciences Corp. +                          812,700
         14,420     Juniper Networks Inc. +                          2,811,900
-------------------------------------------------------------------------------
                                                                    20,106,202
-------------------------------------------------------------------------------
COMPUTER SOFTWARE -- 18.8%
         15,000     Adobe Systems Inc.                               1,140,937
         10,154     Check Point Software Technologies Corp. +        1,608,140
         49,632     J.D. Edwards & Co. +                             1,284,228
        228,142     Microsoft Corp. +                               15,713,280
        217,804     Oracle Corp. +                                   7,187,532
         27,091     Peoplesoft Inc. +                                1,182,268
         18,390     Siebel Systems Inc. +                            1,929,801
          8,574     I2 Technologies Inc. +                           1,457,580
         23,581     VERITAS Software Corp. +                         3,325,289
------------------------------------------------------------------------------
                                                                    34,829,055
------------------------------------------------------------------------------
DIVERSIFIED COMMERCIAL SERVICES -- 0.9%
         40,182     Concord EFS Inc. +                               1,660,019
------------------------------------------------------------------------------
DIVERSIFIED ELECTRONIC PRODUCTS -- 1.3%
         30,394     JDS Uniphase Corp. +                             2,475,211
------------------------------------------------------------------------------
ELECTRONIC COMPONENTS -- 0.6%
         25,884     Solectron Corp. +                                1,138,896
------------------------------------------------------------------------------
ELECTRONIC DATA PROCESSING -- 16.1%
         72,037     Compaq Computer Corp.                            2,190,645
        124,329     Dell Computer Corp. +                            3,667,705
         27,900     Electronic Data Systems Corp.                    1,309,556
         97,576     Hewlett Packard Co.                              4,531,185
         88,464     International Business Machines Corp.            8,713,704
         24,800     Palm Inc. +                                      1,328,350
         73,326     Sun Microsystems Inc. +                          8,130,020
------------------------------------------------------------------------------
                                                                    29,871,165
------------------------------------------------------------------------------
ELECTRONIC DATA PROCESSING PERIPHERALS -- 6.6%
         99,232     EMC Corp. +                                      8,837,850
         14,771     Network Appliance Inc. +                         1,757,749
         34,854     Symbol Technologies Inc.                         1,583,679
------------------------------------------------------------------------------
                                                                    12,179,278
------------------------------------------------------------------------------
ELECTRONIC DATA PROCESSING SERVICES -- 2.4%
         18,411     Automatic Data Processing, Inc.                  1,202,468
         21,260     BEA Systems Inc. +                               1,525,405
         35,222     First Data Corp.                                 1,765,503
------------------------------------------------------------------------------
                                                                     4,493,376
------------------------------------------------------------------------------
ELECTRONIC PRODUCTION EQUIPMENT -- 3.7%
         57,969      Applied Materials Inc. +                        3,079,603
         24,698      KLA Tencor Corp. +                                835,101
         47,690      LAM Research Corp. +                              923,994
------------------------------------------------------------------------------
                       See Notes to Financial Statements.


       8 Smith Barney Technology Fund | 2000 Annual Report to Shareholders


<PAGE>


------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                           OCTOBER 31, 2000
------------------------------------------------------------------------------
     SHARES                         SECURITY                           VALUE
------------------------------------------------------------------------------
ELECTRONIC PRODUCTION EQUIPMENT (CONTINUED)
         27,077      Novellus Systems Inc. +                       $ 1,108,465
         13,900      Seagate Technology +                              971,262
------------------------------------------------------------------------------
                                                                     6,918,425
------------------------------------------------------------------------------
INTERNET SERVICES -- 8.1%
        105,476      America Online Inc. +                           5,319,155
         11,032      Ariba Inc. +                                    1,394,169
          8,000      Brocade Communication Systems Inc. +            1,819,000
         15,536      Commerce One Inc. +                               997,217
         25,358      Exodus Communications Inc. +                      851,078
         11,523      Inktomi Corp. +                                   730,990
         79,000      Marchfirst Inc. +                                 459,187
         12,900      Tibco Software Inc. +                             812,700
          9,796      VeriSign Inc. +                                 1,293,072
         23,133      Yahoo! Inc. +                                   1,356,172
-------------------------------------------------------------------------------
                                                                    15,032,740
------------------------------------------------------------------------------
OTHER CONSUMER SERVICES -- 0.5%
         17,265      Ebay, Inc. +                                      889,147
------------------------------------------------------------------------------
SEMI-CONDUCTORS -- 16.8%
         30,438      Altera Corp. +                                  1,246,056
         16,601      Analog Devices Inc. +                           1,079,065
         14,724      Applied Micro Circuits Corp. +                  1,125,466
          6,290      Broadcom Corp. +                                1,398,739
        237,680      Intel Corp.                                    10,695,600
         32,674      LSI Logic Corp. +                               1,074,158
         18,314      Linear Technology Corp.                         1,182,398
         31,865      Microchip Technology Inc. +                     1,007,731
         33,504      Micron Technology Inc. +                        1,164,264
          5,531      PMC Sierra Inc. +                                 937,505
          8,300      Redback Networks Inc. +                           883,431
          4,600      SDL Inc. +                                      1,192,550
         41,583      STmicroelectronics NV                           2,159,717
         85,357      Texas Instruments Inc.                          4,187,828
         12,141      Vitesse Semicondutor Corp. +                      849,111
         12,727      Xilinx Inc. +                                     921,912
------------------------------------------------------------------------------
                                                                    31,105,531
------------------------------------------------------------------------------
TELECOMMUNICATIONS EQUIPMENT -- 12.1%
         34,090     ADC Telecommunications Inc. +                      728,674
         13,750     Ciena Corp. +                                    1,445,469
         11,561     Comverse Technology Inc. +                       1,291,942
         32,648     Corning Inc.                                     2,497,572
        150,116     Lucent Technologies Inc.                         3,499,579
        110,790     Motorola Inc.                                    2,762,826
        130,496     Nortel Networks Corp.                            5,937,568
         11,200     Sycamore Networks Inc. +                           708,400
         38,458     Qualcomm Inc. +                                  2,503,976
         21,346     Tellabs Inc. +                                   1,065,966
------------------------------------------------------------------------------
                                                                    22,441,972
------------------------------------------------------------------------------
                       See Notes to Financial Statements.


       9 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>






------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                            OCTOBER 31, 2000
------------------------------------------------------------------------------
     SHARES                         SECURITY                           VALUE
------------------------------------------------------------------------------
                    TOTAL COMMON STOCK
                    (Identified Cost-- $214,414,075)              $184,383,850
------------------------------------------------------------------------------
      FACE
     AMOUNT                         SECURITY                           VALUE
------------------------------------------------------------------------------

DISCOUNT NOTE -- 0.6%
    $1,095,000      Student Loan Marketing Discount Note
                     6.45% due 11/01/00;
                      (Identified Cost-- $1,095,000)                 1,095,000
------------------------------------------------------------------------------

                    TOTAL INVESTMENTS -- 100%
                    (Identified Cost-- $215,509,075)*             $185,478,850
------------------------------------------------------------------------------

+ Non-income producing security.
* Aggregate cost for federal income taxes is substantially the same.

                       See Notes to Financial Statements.

       10 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>


------------------------------------------------------------------------------
STATEMENT OF ASSETS AND LIABILITIES                           OCTOBER 31, 2000
------------------------------------------------------------------------------
ASSETS:
  Investments, at value (Cost  $215,509,075)                      $185,478,850
  Cash                                                                     837
  Receivable for Fund securities sold                                4,255,451
  Dividends and interest receivable                                      5,340
  Other receivables                                                         94
------------------------------------------------------------------------------
  TOTAL ASSETS                                                     189,740,572
------------------------------------------------------------------------------
LIABILITIES:
  Payable for securities purchased                                     770,509
  Payable for Fund shares purchased                                    144,539
  Distribution fees payable                                            127,197
  Management fees payable                                              118,354
  Accrued expenses and other liabilities                               175,134
------------------------------------------------------------------------------
  TOTAL LIABILITIES                                                  1,335,733
------------------------------------------------------------------------------
TOTAL NET ASSETS                                                  $188,404,839
------------------------------------------------------------------------------
NET ASSETS:
  Par value of capital shares                                     $     20,692
  Capital paid in excess of par value                              232,330,971
  Accumulated net investment loss                                       (7,878)
  Accumulated net realized loss from security transactions         (13,908,721)
  Net unrealized depreciation of investments                       (30,030,225)
------------------------------------------------------------------------------
  TOTAL NET ASSETS                                                $188,404,839
------------------------------------------------------------------------------
SHARES OUTSTANDING:
  Class A                                                            5,072,866
  ----------------------------------------------------------------------------
  Class B                                                            8,162,215
  ----------------------------------------------------------------------------
  Class L                                                            7,457,148
  ----------------------------------------------------------------------------
NET ASSET VALUE:
  Class A (and redemption price)                                         $9.14
  ----------------------------------------------------------------------------
  Class B *                                                              $9.09
  ----------------------------------------------------------------------------
  Class L **                                                             $9.09
  ----------------------------------------------------------------------------
MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
  Class A (net asset value plus 5.26% of net asset value per share)      $9.62
  ----------------------------------------------------------------------------
  Class L (net asset value plus 1.01% of net asset value per share)      $9.18
  ----------------------------------------------------------------------------

*  Redemption  price is NAV of Class B shares  reduced by a 5.00% CDSC if shares
   are redeemed less than one year from initial purchase (See  Note 2).

** Redemption  price is NAV of Class L shares reduced by a 1.00% CDSC if shares
   are redeemed within the first year of purchase.

                       See Notes to Financial Statements.


       11 Smith Barney Technology Fund | 2000 Annual Report to Shareholders
<PAGE>

-------------------------------------------------------------------------------
STATEMENT OF OPERATIONS
-------------------------------------------------------------------------------
FOR THE PERIOD  FEBRUARY 28, 2000  (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

INVESTMENT INCOME:
     Interest                                                         $ 146,462
     Dividends                                                           95,389
     Less: Foreign withholding tax                                         (873)
-------------------------------------------------------------------------------
     TOTAL INVESTMENT INCOME                                            240,978
-------------------------------------------------------------------------------
EXPENSES:
     Management fees(Note 2)                                          1,106,818
     Distribution fees (Note 2)                                         961,426
     Custody fees                                                       173,376
     Transfer agent fees                                                 92,439
     Shareholder communications                                          54,703
     Registration fees                                                   53,772
     Legal fees                                                          34,560
     Audit fees                                                          17,000
     Directors' fees                                                      7,727
     Other                                                               35,693
-------------------------------------------------------------------------------
     TOTAL EXPENSES                                                   2,537,514
     Less: Aggregate amount waived by the Manager (Note 2)              (96,394)
-------------------------------------------------------------------------------
     NET EXPENSES                                                     2,441,120
-------------------------------------------------------------------------------
NET INVESTMENT LOSS                                                  (2,200,142)
-------------------------------------------------------------------------------
REALIZED AND UNREALIZED LOSS ON INVESTMENTS (NOTE 3):
     Realized Loss From:
        Security transactions (excluding short-term securities)     (13,908,721)
-------------------------------------------------------------------------------
     Decrease in Net Unrealized Depreciation                        (30,030,225)
-------------------------------------------------------------------------------
NET LOSS ON INVESTMENTS                                             (43,938,946)
-------------------------------------------------------------------------------
DECREASE IN NET ASSETS FROM OPERATIONS                             $(46,139,088)
-------------------------------------------------------------------------------




                       See Notes to Financial Statements.


      12 Smith Barney Technology Fund | 2000 Annual Report to Shareholders


<PAGE>

-------------------------------------------------------------------------------
 STATEMENT OF CHANGES IN NET ASSETS
-------------------------------------------------------------------------------
FOR THE PERIOD FEBRUARY 28, 2000 (COMMENCEMENT OF OPERATIONS) TO
OCTOBER 31, 2000

OPERATIONS:
     Net investment loss                                           $ (2,200,142)
     Net realized loss                                              (13,908,721)
     Decrease in net unrealized depreciation                        (30,030,225)
-------------------------------------------------------------------------------
     DECREASE IN NET ASSETS FROM OPERATIONS                         (46,139,088)
-------------------------------------------------------------------------------
FUND SHARE TRANSACTIONS (NOTE 6):
     Net proceeds from sale of shares                               258,490,217
     Net asset value of shares issued for reinvestment of dividends          --
     Cost of shares reacquired                                      (23,946,290)
-------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS            234,543,927
-------------------------------------------------------------------------------
INCREASE IN NET ASSETS                                              188,404,839
NET ASSETS:                                                         188,404,839
     Beginning of period                                                     --
-------------------------------------------------------------------------------
     END OF PERIOD*                                                $188,404,839
-------------------------------------------------------------------------------
* Includes accumulated net investment loss of:                      $    (7,878)
-------------------------------------------------------------------------------
                       See Notes to Financial Statements.


       13 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>
--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1. SIGNIFICANT ACCOUNTING POLICIES

The Smith Barney  Technology  Fund is a  non-diversified  investment fund of the
Smith Barney Sector Series Inc. (the  "Company"),  a Maryland  corporation.  The
Company is registered  under the Investment  Company of 1940, as amended,  as an
open-end management  investment company and consists of this Fund and five other
separate  investment funds:  Smith Barney Financial  Services Fund, Smith Barney
Health  Sciences  Fund,  Smith Barney Global  Biotechnology  Fund,  Smith Barney
Global Media & Telecommunications  Fund and Smith Barney Global Technology Fund.
On February 28, 2000, the Fund commenced operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed  to be  over-the-counter)  and the  securities  for  which  no sale was
reported  on that date are valued at the mean  between  the bid and ask  prices.
Securities  which are listed or traded on more than one  exchange  or market are
valued at the quotations on the exchange or market  determined to be the primary
market for such securities;  (c) securities for which market  quotations are not
available  will be valued  in good  faith at fair  market  value by or under the
direction of the Board of Directors;  (d) securities maturing within 60 days are
valued  at cost  plus  accreted  discount,  or minus  amortized  premium,  which
approximates  value;  (e) the  accounting  records of the Fund are maintained in
U.S. dollars.  All assets and liabilities  denominated in foreign currencies are
translated  into U.S.  dollars based on the rate of exchange of such  currencies
against  U.S.  dollars  on  the  date  of  valuation.  Purchases  and  sales  of
securities,  and income and  expenses  are  translated  at the rate of  exchange
quoted on the respective date that such  transactions are recorded.  Differences
between  income or expense  amounts  recorded and collected or paid are adjusted
when reported by the custodian;  (f) interest income,  adjusted for amortization
or premium and  accretion  of  discount,  is recorded on an accrual  basis;  (g)
dividend  income is recorded on the  ex-dividend  date;  foreign  dividends  are
recorded  on the  ex-dividend  date or as  soon  as  practical  after  the  Fund
determines the existence of a dividend  declaration after exercising  reasonable
due diligence;  (h) dividends and  distributions to shareholders are recorded on
the  ex-dividend  date;  (i)  gains  or  losses  on the sale of  securities  are
calculated by using the specific  identification method; (j) direct expenses are
charged to each class; management fees and general expenses are allocated on the
basis of  relative  net  assets;  (k) the  character  of income  and gains to be
distributed are determined in accordance with income tax regulations,  which may
differ from generally accepted  accounting  principles;  (l) the Fund intends to
comply with the  requirements of the Internal  Revenue Code of 1986, as amended,
pertaining  to  regulated  investment  companies  and to make  distributions  of
taxable income  sufficient to relieve it from  substantially  all Federal income
and excise  taxes;  (m) the character of income and gains to be  distributed  in
accordance with income tax regulations which may differ from generally  accepted
accounting principles.  At October 31, 2000,  reclassifications were made to the
Fund's capital accounts to reflect permanent book/tax  difference and income and
gains available for distribution under income tax regulations.  Accordingly, the
Fund reclassified  $2,192,264 from paid in capital to accumulated net investment
loss. Net investment income, net realized gains and net assets were not affected
by this  adjustment  and (n) estimates and  assumptions  are required to be made
regarding  assets,   liabilities  and  changes  in  net  assets  resulting  from
operations  when  financial   statements  are  prepared.   Changes  in  economic
environment,  financial  markets and any other  parameters  used in  determining
these estimates could cause actual results to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market  rate as an  unrealized  gain or  loss.  Realized  gains  or  losses  are
recognized when contracts are settled.


       14 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------
2. MANAGEMENT AGREEMENT AND
OTHER TRANSACTIONS

SSB Citi Fund  Management LLC ("SSBC"),  formerly  known as SSBCFund  Management
Inc., a subsidiary of Salomon Smith Barney  Holdings Inc.  ("SSBH"),  which,  in
turn,  is a  subsidiary  of Citigroup  Inc.  ("Citigroup"),  acts as  investment
manager to the Fund.  The  management fee is computed at an annual rate of 0.95%
of the average daily net assets.  SSBC has delegated the daily management of the
Portfolio to Citibank  N.A.,  (the  "SubAdviser"),  an  affiliate  of SSBC.  For
services provided to the Fund, the manager pays the Subadviser a subadvisory fee
computed at an annual rate of 0.65% of the Fund's average daily net assets.  The
manage-ment  fees paid amounted to  $1,106,818,  of which $96,394 was waived for
the period ended October 31, 2000.

Salomon  Smith Barney Inc.  ("SSB"),  another  subsidiary  of SSBH,  acts as the
Fund's  distributor as well as certain other  broker-dealers,  continues to sell
Fund shares to the public as a member of the selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and  PFPCGlobal  Fund Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTCreceives  fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $92,439 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
-------------------------------------------------------------------
CDSCs                          --          $97,000     $ 27,000
-------------------------------------------------------------------
Sales Charges              $1,020,000      $95,000     $800,000
-------------------------------------------------------------------

Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
-------------------------------------------------------------------
Distribution Plan Fees       $67,882      $464,979     $428,565
-------------------------------------------------------------------

All officers and one Director of the Fund are employees of SSB.

3. INVESTMENTS

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

-------------------------------------------------------------------
Purchases                                          $270,800,845
-------------------------------------------------------------------
Sales                                              $ 42,478,049
-------------------------------------------------------------------

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

-------------------------------------------------------------------
Gross unrealized appreciation                     $  11,073,729
Gross unrealized depreciation                       (41,103,954)
-------------------------------------------------------------------

Net unrealized depreciation                       $ (30,030,225)
-------------------------------------------------------------------


      15 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>
--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

4. REPURCHASE AGREEMENTS

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Fund requires continual  maintenance
of the market  value of the  collateral  (plus  accrued  interest) in amounts at
least equal to the repurchase price.

5. CONCENTRATION OF RISK

The Fund  normally  invests  at least 80% of its  assets in  technology  related
investments.  As a result of this concentration  policy,  which is a fundamental
policy of the Fund,  the Fund's  investments  may be subject to greater risk and
market fluctuation than a fund that invests in securities representing a broader
range of investment alternatives.

The Fund's  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S. dollar can  significantly  affect the value of these investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.

6. CAPITAL SHARES

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.

At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:
                             CLASS A      CLASS B      CLASS L
-------------------------------------------------------------------
Total Paid-in Capital      $56,899,606  $92,585,090 $85,059,231
-------------------------------------------------------------------

Transactions in shares of each class were as follows:

                                           FEBRUARY 28, 2000
                                      (COMMENCEMENT OF OPERATIONS)
                                           TO OCTOBER 31, 2000
                                       SHARES                AMOUNT
--------------------------------------------------------------------
CLASS A
Shares sold                        5,960,086             $66,468,519
Shares issued on reinvestment             --                      --
Shares reacquired                   (887,220)             (9,568,913)
--------------------------------------------------------------------
Net Increase                       5,072,866             $56,899,606
--------------------------------------------------------------------
CLASS B
Shares sold                        8,748,636             $98,765,665
Shares issued on reinvestment             --                      --
Shares reacquired                   (586,421)             (6,180,575)
--------------------------------------------------------------------
Net Increase                       8,162,215             $92,585,090
--------------------------------------------------------------------
CLASS L
Shares sold                        8,248,332             $93,256,033
Shares issued on reinvestment             --                      --
Shares reacquired                   (791,184)             (8,196,802)
--------------------------------------------------------------------
Net Increase                       7,457,148             $85,059,231
--------------------------------------------------------------------

7. CAPITAL LOSS CARRYFORWARD

At October 31, 2000,  the Fund had, for Federal  income tax purposes,  a capital
loss  carryforward  of  approximately  $10,602,000,  available to offset  future
capital gains expiring  October 31, 2008. To the extent that these  carryforward
losses are used to offset capital gains, it is probable that any gains so offset
will not be distributed.

      16 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

For a share of each class of capital stock from February 28, 2000  (Commencement
of Operations) to October 31, 2000



CLASS A SHARES
------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.07)
   Net realized and unrealized loss                                   (2.19)
------------------------------------------------------------------------------
Total Loss From Operations                                            (2.26)
------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                 --
   Net realized gain                                                     --
------------------------------------------------------------------------------
Total Distributions                                                      --
------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                        $9.14
------------------------------------------------------------------------------
TOTAL RETURN                                                         (19.82)%++
------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                   $46,363
------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            1.52%+
   Net investment loss                                                (1.31)%+
------------------------------------------------------------------------------
Portfolio Turnover Rate                                                  24%
------------------------------------------------------------------------------

Note: If Agents of the Fund had not voluntarily  waived a portion of their fees,
the net investment loss per share and the ratios would have been as follows:

  Net investment loss per share                                      $(0.07)
  RATIOS:
  Expenses to average net assets                                       1.60 %+
  Net investment loss to average net assets                           (1.39)%+
-------------------------------------------------------------------------------

+  Annualized.

++ Total return is not annualized,  as it may not be representative of the total
   return for the year.




                       See Notes to Financial Statements.



       17 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

-------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS (CONTINUED)
-------------------------------------------------------------------------------
For a share of each class of capital stock from February 28, 2000  (Commencement
of Operations) to October 31, 2000



CLASS B SHARES
--------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.12)
   Net realized and unrealized loss                                   (2.19)
--------------------------------------------------------------------------------
Total Loss From Operations                                            (2.31)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                 --
   Net realized gain                                                     --
--------------------------------------------------------------------------------
Total Distributions                                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                        $9.09
--------------------------------------------------------------------------------
TOTAL RETURN                                                         (20.26)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                   $74,227
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            2.27%+
   Net investment loss                                                (2.06)%+
-------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                                  24%
-------------------------------------------------------------------------------

Note:  If Agents of the Fund had not  voluntarily  waived a portion of their
       fees,  the net  investment  loss per share and the ratios
       would have been as follows:
       Net investment loss per share                                 $(0.12)
       RATIOS:
       Expenses to average net assets                                  2.35 %+
       Net investment loss to average net assets                      (2.14)%+
-------------------------------------------------------------------------------

++    Total return is not annualized, as it may not be representative of the
      total return for the year.
+     Annualized.




                       See Notes to Financial Statements.

       18 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------
For a share of each class of capital stock from February 28, 2000  (Commencement
of Operations) to October 31, 2000



CLASS L SHARES
--------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.12)
   Net realized and unrealized loss                                   (2.19)
--------------------------------------------------------------------------------
Total Loss From Operations                                            (2.31)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                --
   Net realized gain                                                    --
--------------------------------------------------------------------------------
Total Distributions                                                     --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                        $9.09
--------------------------------------------------------------------------------
TOTAL RETURN                                                         (20.26)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                   $67,815
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            2.27%+
   Net investment loss                                                (2.06)%+
--------------------------------------------------------------------------------
Portfolio Turnover Rate                                                 24%
--------------------------------------------------------------------------------

Note:  If Agents of the Fund had not  voluntarily  waived a portion of their
       fees,  the net  investment  loss per share and the ratios
       would have been as follows:
       Net investment loss per share                                 $(0.12)
       RATIOS:
       Expenses to average net assets                                  2.35%+
       Net investment loss to average net assets                      (2.14)%+
-------------------------------------------------------------------------------

+  Annualized.
++ Total return is not annualized, as it may not be representative of the total
   return for the year.




                       See Notes to Financial Statements.

       19 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

-------------------------------------------------------------------------------
INDEPENDENT AUDITORS' REPORT
-------------------------------------------------------------------------------


TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTOR SERIES INC.:

We have audited the accompanying statement of assets and liabilities,  including
the schedule of  investments,  of Smith Barney  Technology  Fund of Smith Barney
Sector Series Inc. as of October 31, 2000, the related statements of operations,
the statements of changes in net assets and financial  highlights for the period
February 28, 2000  (Commencement of Operations)  through October 31, 2000. These
financial  statements  and financial  highlights are the  responsibility  of the
Fund's  management.  Our  responsibility  is to  express  an  opinion  on  these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney  Technology  Fund of Smith  Barney  Sector  Series Inc. as of October 31,
2000, the results of its operations, the changes in its net assets and financial
highlights  for the period  February  28,  2000  through  October 31,  2000,  in
conformity with accounting principles generally accepted in the United States of
America.


                                                       /s/ KPMG LLP
                                                       ------------


New York, New York
December 11, 2000



       20 Smith Barney Technology Fund | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY
TECHNOLOGY FUND
--------------------------------------------------------------------------------



    DIRECTORS
    Herbert Barg
    Alfred J. Bianchetti
    Martin Brody
    Dwight B. Crane
    Burt N. Dorsett
    Elliot S. Jaffe
    Stephen E. Kaufman
    Joseph J. McCann
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.
    James J. Crisona, Emeritus


    OFFICERS
    Heath B. McLendon
    President and Chief Executive Officer

    Lewis E. Daidone
    Senior Vice President and Treasurer

    Irving P. David
    Controller

    Christina T. Sydor
    Secretary

    INVESTMENT MANAGER
    SSB Citi Fund Management LLC

    INVESTMENT SUBADVISER
    Citibank, N.A.

    DISTRIBUTORS
    Salomon Smith Barney Inc.
    PFS Distributors Inc.

    CUSTODIAN
    State Street Bank & Trust Co.

    TRANSFER AGENT
    Citi Fiduciary Trust Company
    125 Broad Street, 11th Floor
    New York, New York 10004

    SUB-TRANSFER AGENT
    PFPC Global Fund Services
    P.O. Box 9699
    Providence, Rhode Island
    02940-9699

<PAGE>


SMITH BARNEY TECHNOLOGY FUND
--------------------------------------------------------------------------------

                    This report is submitted for general information of the
                    shareholders of Smith Barney Sector Series Inc. -- Smith
                    Barney Technology Fund, but it may also be used as sales
                    literature when preceded or accompanied by the current
                    Prospectus, which gives details about charges, expenses,
                    investment objectives and operating policies of the Fund. If
                    used as sales material after January 31, 2001, this report
                    must be accompanied by performance information for the most
                    recently completed calendar quarter.

                    SMITH BARNEY  TECHNOLOGY  FUND
                    Smith Barney Mutual Funds
                    388 Greenwich Street, MF-2
                    New York, New York 10013

                    For complete information on any Smith Barney Mutual Funds,
                    including management fees and expenses, call or write your
                    financial professional for a free prospectus. Read it
                    carefully before you invest or send money.



                    www.smithbarney.com/mutualfunds

                                                     [SALOMON SMITH BARNEY LOGO]


                    Salomon Smith Barney is a service mark of Salomon
                    Smith Barney Inc.



                     FD02129 12/00


<PAGE>

--------------------------------------------------------------------------------
                                  SMITH BARNEY
                               SECTOR SERIES INC.
                            GLOBAL BIOTECHNOLOGY FUND
--------------------------------------------------------------------------------
               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000








[LOGO] SMITH BARNEY MUTUAL FUNDS
               YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED(SM).


--------------------------------------------------------------------------------
             NOT FDIC INSURED O NOT BANK GUARANTEED O MAY LOSE VALUE
--------------------------------------------------------------------------------

<PAGE>



[GRAPHIC] Research Series

Annual Report o October 31, 2000

SMITH BARNEY GLOBAL
BIOTECHNOLOGY FUND

CITIBANK GLOBAL
ASSET MANAGEMENT

Citibank, N.A., through its Citibank Global Asset Management division is the
subadviser to the Fund. Comprising a seasoned group of investment and research
professionals, the Fund's management team follows a systematic and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks long-term capital appreciation. The Fund normally invests at
least 80% of its assets in securities of companies principally engaged in, but
not limited to, the research, development, application, manufacturing and
distribution of various biotechnological and biomedical products, services,
processes and related technologies.

FUND FACTS

FUND INCEPTION
-----------------------------------------------
August 31, 2000

           CLASS A     CLASS B     CLASS L
-----------------------------------------------
NASDAQ      SMBAX         --          --
-----------------------------------------------
INCEPTION  8/31/00     8/31/00      8/31/00
-----------------------------------------------


SMITH BARNEY GLOBAL BIOTECHNOLOGY FUND*
TOTAL RETURNS OCTOBER 31, 2000

                        WITHOUT SALES CHARGES(1)
                   Class A      Class B    Class L
-------------------------------------------------------
Since Inception    (13.33)%    (13.51)%   (13.51)%
(August 31, 2000)**
-------------------------------------------------------

                          WITH SALES CHARGES(2)
                   Class A      Class B    Class L
-------------------------------------------------------
Since Inception    (17.67)%    (17.83)%   (15.23)%
(August 31, 2000)**
-------------------------------------------------------


*    Since the Fund focuses its investments on companies involved in the
     biotechnology industries, an investment in the Fund may involve a greater
     degree of risk than an investment in other mutual funds with greater
     diversification.

**   Not Annualized

(1)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value and does not reflect deduction of all applicable
     sales charges with respect to Class A and L shares of the applicable
     contingent deferred sales charges ("CDSC") with respect to Class B and L
     shares.

(2)  Assumes reinvestment of all dividends and capital gain distributions, if
     any at net asset value. In addition, Class A and L shares reflect the
     deduction of the maximum sales charge of 5.00% and 1.00%, respectively; and
     Class B shares reflect the deduction of a 5.00% CDSC, which applies if
     shares are redeemed within one year from initial purchase. Thereafter, this
     CDSC declines by 1.00% per year until no CDSC is incurred. Class L shares
     also reflect the deduction of a 1.00% per year until no CDSC is incurred.
     Class L shares also reflect the deduction of 1.00% CDSC, which applies if
     shares are redeemed within the first year of purchase.

--------------------------------------------------------------------------------
WHAT'S INSIDE
Your Investment in the Smith Barney
Global Biotechnology Fund ................. 1
Letter from the Chairman .................. 2
Fund at a Glance .......................... 3
Shareholder Letter ........................ 4
Schedule of Investments ................... 8
Statement of Assets and Liabilities .......10
Statement of Operations ...................11
Statement of Changes in Net Assets ........12
Notes to Financial Statements .............13
Financial Highlights ......................17
Independent Auditors' Report ..............20

[LOGO] SMITH BARNEY MUTUAL FUNDS
       YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)


--------------------------------------------------------------------------------
  Investment Products: Not FDIC Insured o Not Bank Guaranteed o May Lose Value
--------------------------------------------------------------------------------

<PAGE>

--------------------------------------------------------------------------------
                       YOUR INVESTMENT IN THE SMITH BARNEY
                            GLOBAL BIOTECHNOLOGY FUND
--------------------------------------------------------------------------------
EXPOSURE TO GROWTH OPPORTUNITIES

Led by Citibank N.A. through its Global Asset Management ("CGAM") division, the
Fund offers investors an opportunity to participate in the long-term growth
potential of the global biotechnology industry.


[GRAPHIC]

     DISCOVERIES AND IMPROVEMENTS SPUR INCREASED GROWTH
     An accelerated pace of discovery and improvements in development and
     testing processes have led to significant growth opportunities for many
     biotechnology companies.

[GRAPHIC]
     DIVERSIFICATION IN A TARGETED SECTOR*
     An investment in the Fund offers investors a way to participate in a broad
     range of companies in the biotechnology sector, both in the U.S. and
     abroad. The Fund's investments may include companies involved in many
     different areas, including the research, development, application,
     manufacture and distribution of various biotechnological and biomedical
     products, services, processes and related technologies.

[GRAPHIC]
     THE BENEFITS OF EXHAUSTIVE  FUNDAMENTAL  SECURITIES ANALYSIS-- THE RESEARCH
     SERIES
     The Research Series is a selection of Smith Barney Mutual Funds built on a
     foundation of substantial buy-side research under the direction of CGAM.
     This series of funds focus on potential opportunities from well-defined
     industries, sectors and trends.

[GRAPHIC]
     A COMMITMENT TO MANAGING YOUR SERIOUS MONEY
     SSB Citi Asset Management Group ("SSB Citi"), the investment management
     division of Citigroup, comprises Smith Barney Asset Management, Salomon
     Brothers Asset Management and Citibank Global Asset Management, each an
     organization with extensive investment capabilities.

     SSB Citi, as a member of one of the largest financial services providers in
     the world, offers you the benefits of our unparalleled global capabilities.

     At  SSB  Citi,   you  gain  access  to   portfolio   management   delivered
     professionally.  We are proud to offer you, the serious investor, a variety
     of managed solutions.




*    Please note that because the Fund invests in a single industry, its shares
     do not represent a complete investment program and the value of its shares
     may fluctuate more than shares invested in a broader range of industries.


  1 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


--------------------------------------------------------------------------------
                            LETTER FROM THE CHAIRMAN
--------------------------------------------------------------------------------

The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks may be running  out of steam.  At SSB Citi Asset
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.


We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their businesses. Today, with over $398.6 billion in assets under management,(1)
SSB Citi offers  choices and  solutions,  uniting the  distinguished  history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.


A FEW THOUGHTS ON SECTOR INVESTING

Over the past few years,  we have seen how profoundly the  advancements  made in
sectors  such  as  technology  have   transformed  our  daily  lives.   Computer
applications,  wireless  communications  and  biotechnological  discoveries have
created new  investment  opportunities.  The new and  developing  sectors of the
economy that are involved in bringing these products,  services and technologies
to life may  offer  exceptional  growth  potential,  and many  investors  should
consider having a portion of their investment portfolios in them.

Although most of us recognize that certain sectors drive the global economy,  we
believe  it is much  more  difficult  to  determine  which  companies  within  a
particular  sector will  perform  better than the others over time.  The team of
experienced  professionals at Citibank N.A. thoroughly  researches a broad range
of  companies  within a given sector and  carefully  analyzes  them,  looking to
identify those companies that they believe offer the greatest  growth  potential
over the long term. Through this exhaustive and proprietary process,  CGAM seeks
to offer an opportunity  to participate in those  companies that it believes are
best-positioned in their respective industries.

[PHOTO OMITTED]
HEATH B. MCLENDON
CHAIRMAN

-----------------

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.


When you  invest  with SSB Citi  you can do so with  the  confidence  that  your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.


Thank you for your confidence in our investment management approach.


Sincerely,

/s/ Heath B. McLendon
----------------------


Heath B. McLendon
Chairman

November 6, 2000



-----------
(1)  As of October 31, 2000. This figure represents retail,  institutional,
     money and separate accounts.


  2 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


--------------------------------------------------------------------------------
 SMITH BARNEY GLOBAL BIOTECHNOLOGY FUND AT A GLANCE (UNAUDITED)
--------------------------------------------------------------------------------
GROWTH OF $10,000 INVESTED IN SHARES OF THE
SMITH BARNEY GLOBAL BIOTECHNOLOGY FUND VS. MSCI ALL-WORLD INDEX
--------------------------------------------------------------------------------
                August 31, 2000 (Commencement of Operations) -- October 31, 2000

[The following table represents a line chart in the printed piece.]
               Class A     MSCI
8/30/00         9500      10000
9/30/00         9275      9469
10/31/00        8233      9312


A $10,000  investment in the Fund made on August 31, 2000 would have declined to
$8,233 with sales charge (as of October 31, 2000).  The graph shows how the fund
compares to its  benchmark for the same period.  The graph  includes the initial
sales charge on the Fund (no comparable charge exists for the index) and assumes
all dividends and  distributions  are reinvested at Net Asset Value.

*    The Morgan Stanley Capital International All-World Index ("MSCI All-World")
     represents  the  performance  of 47 markets in both the  developed  and the
     emerging  markets in Africa,  Asia,  Australia,  Europe,  North America and
     South America.  Please note that an investor  cannot invest  directly in an
     index.

--------------------------------------------------------------------------------
                         TOP TEN COMMON STOCK HOLDINGS*
--------------------------------------------------------------------------------

---------------------------------------------------
1. Amgen Inc. .................................20.7%

2. Medimmune Inc. ..............................9.5

3. Protein Design Labs Inc. ....................5.3

4. Vertex Pharmaceuticals Inc. .................4.9

5. Sepracor Inc. ...............................4.2

6. Celgene Corp. ...............................3.8

7. QLT Inc. ....................................3.1

8. PE Celera Genomics Group ....................3.0

9. COR Therapeutics Inc. .......................2.7

10. Biochemical Pharmaceuticals Inc. ...........2.7

----------------------------------------------------
* As a percentage of total investments.


--------------------------------------------------------------------------------
                             INVESTMENT ALLOCATION*
--------------------------------------------------------------------------------

[REPRESENTATION OF PIE CHART]

 1.2%   United Kingdom
 2.5%   Switzerland
 2.6%   Short-Term
 6.6%   Canada
87.1%   United States


 3 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders



<PAGE>

Dear Shareholder,

We are  pleased to provide  the  inaugural  annual  report for the Smith  Barney
Sector  Series  Inc.--Smith  Barney Global  Biotechnology  Fund ("Fund") for the
period from August 31, 2000  through  October 31,  2000.  In this report we have
summarized the period's  prevailing  economic and market conditions and outlined
our investment strategy.  The information provided in this letter represents the
opinion of the manager and is not intended to be a forecast of future events,  a
guarantee of future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 9 for a complete list and  percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE

Since its  inception  on August 31, 2000 through  October 31,  2000,  the Fund's
Class A shares,  without and with sales charges  generated  negative  returns of
13.33% and 17.67%,  respectively.  In  comparison,  the Morgan  Stanley  Capital
International  All World Index ("MSCI All-World  Index")(1)  returned a negative
6.88% for the same period.  Please note that past  performance is not indicative
of future results.

GLOBAL SECTOR INVESTING--THE CGAM PROCESS

Our approach to global sector investing is based on exhaustive  research that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive  industry  expertise.  We  look  for  analytical  consistency  through
intensive modeling and strict application of a consistent valuation methodology.

The  Fund's  management  team is made up of a  high-quality,  seasoned  group of
investment  and  research  professionals  who follow a  systematic  and rigorous
strategy designed to provide the right exposure to various industries within any
particular sector they cover. CGAM's exhaustive fundamental research evaluates a
universe of  businesses  in its global  quest to  identify  and  participate  in
attractive investment opportunities.

                         A THREE-STEP RESEARCH PROCESS

         FUNDAMENTAL --------> QUANTITATIVE --------> ACTIVE PORTFOLIO
          RESEARCH               RESEARCH                MANAGEMENT


We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to  create  portfolios  that we think  should  generate  competitive
returns while helping to moderate risk over time.



---------------
(1)  THE MSCI ALL-WORLD INDEX  REPRESENTS THE PERFORMANCE OF MARKETS IN BOTH THE
     DEVELOPED  AND THE EMERGING  MARKETS IN AFRICA,  ASIA,  AUSTRALIA,  EUROPE,
     NORTH AMERICA AND SOUTH AMERICA. PLEASE NOTE THAT AN INVESTOR CANNOT INVEST
     DIRECTLY IN AN INDEX.


  4 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>

--------------------------------------------------------------------------------
                     BY MAPPING THE STRUCTURE OF HUMAN DNA,
                    SCIENTISTS HAVE OPENED THE DOOR FOR THE
                     FURTHER DISCOVERY AND DEVELOPMENT OF A
                     NEW GENERATION OF INNOVATIVE DRUGS TO
                  TREAT COMPLEX DISEASES. IN THE EARLY 1990S,
                   THERE WERE APPROXIMATELY 100 DRUGS IN THE
                             BIOTECHNOLOGY AREA IN
                     VARIOUS STAGES OF DEVELOPMENT. TODAY,
                      THERE ARE OVER 1,000 IN DEVELOPMENT.

                             SOURCE: ERNST & YOUNG.
--------------------------------------------------------------------------------

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)

Our  fundamental,  proprietary  research  can  add  value  to  active  portfolio
management by providing timely and unbiased  information to our  decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

o Superior products or services
o Outstanding managements
o Solid balance sheets
o Market leadership
o Leading innovation

In our opinion,  these are the  companies'  strengths that can create real value
and lead to strong  earnings and sales  growth,  which  ultimately  drives stock
prices.

THE CGAM RESEARCH PROCESS DEFINED

We look to differentiate  ourselves from the traditional  approach to investment
management in a number of ways that we think can add value to the portfolio. Our
management  style  can best be  described  as  disciplined,  yet  flexible.  Our
formidable  global  reach and local  expertise  enable them to nurture  research
teams with direct access to the regions and  industries  where they do business.
Our research  organization is centered on a team-approach  to stock research and
selection by covering  hundreds of companies and working  closely  together both
within  and  across  industry  teams in a  seamless  fashion  to reach a prudent
consensus.




  5 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


--------------------------------------------------------------------------------
                      IN 1999, 12,735 BIOTECHNOLOGY PATENTS
                      WERE GRANTED, A SIGNIFICANT INCREASE
                FROM 1985, WHEN ONLY 3,394 PATENTS WERE GRANTED.

              SOURCE: U.S. PATENT AND TRADEMARK OFFICE, JUNE 2000.
--------------------------------------------------------------------------------

Each stock analyst builds intensive,  detailed company models from the ground up
that anticipate a particular company's financial  performance.  These models are
based on the company's  competitive  position  within the  industry,  quality of
product offerings,  costs and risks. These intensive models detail the analyst's
assumptions  for  potential  profitability  for the company going  forward,  and
provides some of the necessary  information to forecast company fundamentals and
make stock  recommendations.  The research team looks to ensure  consistency  in
industry  and  accounting  assumptions  and that in turn can  allow  for  better
comparisons of earnings forecasts.

A common valuation framework-based on the Dividend Discount Model ("DDM") allows
for  estimation  of returns to fair value.  Simply  stated,  the DDM  compares a
company's future discounted dividend stream to its current stock price.

We  believe  that  is a  valuable  and  consistent  method  to  provide  current
valuations to securities. The DDM-based valuation process, in our view, provides
a common  yardstick  that helps  analysts  and  portfolio  managers  compare the
relative  valuation of one company's  stock to another.  The equity analyst then
combines  the DDM  valuation  together  with other  fundamental  factors such as
earnings surprises to come up with an investment rating on a company's stock.

GLOBAL BIOTECHNOLOGY SECTOR UPDATE

We believe  that present  global  economic  conditions  are  favorable  for many
biotechnology companies. A demographic shift towards an aging population has led
to rising drug consumption worldwide.  As such, healthcare and drug spending has
continued to rise in recent years. In addition, political and regulatory factors
such as proposed  Medicare  reform and the U.S.  Food and Drug  Administration's
(FDA) streamlining of the drug approval process has had a positive impact on the
industry.

We apply a systematic  methodology to "see through" the recent hype  surrounding
biotechnology.  We believe that our extensive biotechnology experience allows us
to form a full  understanding  of the subtleties of the therapeutic  markets and
the applications of clinical data. With this in-depth understanding, we are able
to  identify  what we deem  to be  solid  companies  with  compelling  long-term
prospects.

The  global  biotechnology  industry  continued  its  practice  of  establishing
strategic partnerships with pharmaceutical companies to develop new drugs during
the period.  These  arrangements  convinced many investors that these  alliances
could  potentially  result in the creation of viable new products.  In addition,
many  biotechnology  companies have continued to make  development and licensing
agreements  that  could  lead to  improved  marketing  initiatives  for some new
therapies.

Positive  news  flow  benefiting  a  number  of  companies  also  came  from the
Interscience  Conference on Antimicrobial  Agents and  Chemotherapy  (ICAAC(2)).
This  conference  marked the start of a run of conferences  which should provide
further positive news flow on products in development, with the American Society
of Human Genetics meeting starting in early October.

The  political  landscape  has  also  improved  somewhat  in the  U.S.  for  the
biotechnology  sector.  It appears more likely that any major healthcare  reform
will not pass until next year. In addition, the proposals put forward by the two
leading  Presidential  candidates  may have a limited  impact  on  biotechnology
stocks.



-------------

(2)  THE ICAAC,  SPONSORED BY JOHNS HOPKINS UNIVERSITY'S  DIVISION OF INFECTIOUS
     DISEASES,  IS  HELD  ANNUALLY  AND  IS  ATTENDED  BY  APPROXIMATELY  12,000
     SCIENTISTS, PHYSICIANS,  RESEARCHERS, CLINICIANS AND PHARMACISTS TO DISCUSS
     NEW ADVANCES IN THE HEALTH SCIENCES INDUSTRY.



  6 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


--------------------------------------------------------------------------------
                       EACH CGAM ANALYST BUILDS INTENSIVE,
                     DETAILED COMPANY MODELS FROM THE GROUND
                    UP THAT SEEKS TO ANTICIPATE A PARTICULAR
                    COMPANY'S FUTURE FINANCIAL PERFORMANCE.
--------------------------------------------------------------------------------

The  investment  strategy  for  the  Fund is to  invest  in what we deem to be a
diversified   portfolio  of   biotechnology   companies   across  the  different
disciplines  that make up this  sector.  The Fund  currently  has  positions  in
diversified   therapeutic  companies,   "enablers"  (i.e.,  companies  producing
products which allow other firms to carry out research, either through equipment
or information) and mid- to late-stage research companies. We evaluate companies
on four  criteria--profitability  (i.e.,  current or  near-term),  partnerships,
products and pipeline. The higher a company rates on each of these criteria, the
larger  the  position  we will take in the  company.  Different  from many other
biotechnology  funds, we focus on the longer-term outlook for each company,  and
subsequently have lower turnover than other, more  "theme-driven"  funds.  While
the Fund is a global fund,  holding  securities of firms based in at least three
countries,  including the U.S.,  the sector itself tends to be  U.S.-based,  and
consequently the Fund is made up of almost 90% U.S. stocks.

The Fund has positions in companies such as Amgen Inc.,  Biogen Inc. and Serono,
enablers such as Protein  Design Labs Inc. and  research-focused  companies like
Abgenix  Inc.  and QLT Inc.  Many of the Fund's  largest  holdings  are  already
profitable--Serono  SA,  Chiron Corp.,  Amgen Inc.,  Genentech  Inc.,  Medimmune
Inc.--which  we feel may help the Fund  weather  any  future  volatility  in the
sector.

We also believe in diversifying our bets within the sector, hence the reason for
the larger number of holdings.  Among the not-yet-profitable  companies held, we
view Abgenix  Inc. as a leader in antibody  therapeutics,  having four  products
under development,  a good array of partnerships and strong momentum. QLTI Inc.,
the research  leader and  innovator  in  photodynamic  therapy  (light-activated
drugs),  derives revenues from an array of royalties and  partnerships  based on
its intellectual property assets.

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT

The  management  of the  sector  funds is  driven  by  analyst  recommendations,
long-term earnings and earnings momentum which form the basis of expected future
returns within any given sector.  These expected returns,  coupled with detailed
risk  forecasts,  determine  what  holdings  will be  selected.  In building and
maintaining  the Fund's  portfolio,  we look to avoid a high  risk-to-return  on
their investments and carefully monitor sector  performance,  constantly looking
for any material changes and/or developments.

Thank you for  investing in the Smith Barney Sector  Series  Inc.--Smith  Barney
Global  Biotechnology Fund. We look forward to helping you pursue your financial
goals in the years ahead.

Sincerely,


The Investment Team at
Citibank N.A.

November 7, 2000


  7 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
 SCHEDULE OF INVESTMENTS                                       OCTOBER 31, 2000
-------------------------------------------------------------------------------
<TABLE>
<CAPTION>

     SHARES                                SECURITY                                             VALUE
-------------------------------------------------------------------------------------------------------
<S>                 <C>                                                                     <C>
COMMON STOCK -- 97.4%
CANADA -- 6.6%
         39,561     Biochemical Pharmaceuticals Inc.* (Pharmaceuticals)                     $   979,135
         29,740     Hemosol Inc.* (Biotechnology)                                               290,099
         22,216     QLT Inc.* (Biotechnology)                                                 1,104,899
-------------------------------------------------------------------------------------------------------
                                                                                              2,374,133
-------------------------------------------------------------------------------------------------------
SWITZERLAND -- 2.5%
            995     Serono SA (Pharmaceuticals)                                                 895,035
-------------------------------------------------------------------------------------------------------
UNITED STATES -- 87.1%
          9,832     Abgenix Inc.* (Pharmaceuticals)                                             775,499
         55,814     Advanced Tissue Sciences Inc.* (Biotechnology)                              397,675
          5,013     Affymetrix Inc.* (Health Care Equipment & Supplies)                         277,595
        128,464     Amgen Inc.* (Biotechnology)                                               7,442,883
         22,770     Aradigm Corp.* (Health Care Equipment & Supplies)                           503,786
         10,275     Aviron* (Biotechnology)                                                     671,728
          7,288     Biogen Inc.* (Biotechnology)                                                438,646
         17,867     Biomatrix Inc.* (Biotechnology)                                             341,706
         21,116     Celgene Corp.* (Biotechnology)                                            1,359,343
          9,439     Cephalon Inc.* (Biotechnology)                                              506,166
         14,566     Chiron Corp.* (Biotechnology)                                               630,890
         17,356     COR Therapeutics Inc.* (Biotechnology)                                      980,614
         13,350     Entremed Inc.* (Biotechnology)                                              415,519
          9,440     Enzo Biochemical Inc.* (Biotechnology)                                      363,440
         10,757     Geltex Pharmaceuticals Inc.* (Biotechnology)                                533,816
          8,294     Genentech Inc.* (Biotechnology)                                             684,255
          5,114     Human Genome Sciences Inc.* (Biotechnology)                                 452,030
          7,904     Immunex Corp.* (Pharmaceuticals)                                            336,414
         14,374     Incyte Genomics Inc.* (Biotechnology)                                       526,448
          7,581     Inhale Therapeutic Systems * (Health Care Equipment & Supplies)             377,155
          7,251     Medarex Inc.* (Biotechnology)                                               443,217
         52,169     Medimmune Inc.* (Biotechnology)                                           3,410,548
          6,148     Millennium Pharmaceuticals* (Biotechnology)                                 446,114
          9,643     Neurogen Corp.* (Biotechnology)                                             303,152
         25,543     Northfield Laboratories Inc.* (Biotechnology)                               282,569
         23,479     Organogenesis Inc.* (Biotechnology)                                         294,427
          5,215     PE Biosystems Group (Health Care Equipment & Supplies)                      610,155
         15,781     PE Celera Genomics Group* (Biotechnology)                                 1,065,217
         13,990     Protein Design Labs Inc.* (Biotechnology)                                 1,889,743
         13,326     Regeneron Pharmaceuticals Inc.* (Biotechnology)                             356,471
         17,776     Sangstat MED Corp.* (Biotechnology)                                         177,760
         21,910     Sepracor Inc.* (Biotechnology)                                            1,492,619
         18,885     Vertex Pharmaceuticals Inc.* (Biotechnology)                              1,758,370
         15,703     Vical Inc.* (Biotechnology)                                                 333,689
         39,802     Xoma Ltd.* (Biotechnology)                                                  485,087
-------------------------------------------------------------------------------------------------------
                                                                                             31,364,746
-------------------------------------------------------------------------------------------------------
UNITED KINGDOM -- 1.2%
         6,844      Cambridge Antibody* (Pharmaceuticals)                                       427,003
-------------------------------------------------------------------------------------------------------
                    TOTAL COMMON STOCK
                    (Identified Cost-- $39,701,436)                                          35,060,917
-------------------------------------------------------------------------------------------------------
</TABLE>


                       See Notes to Financial Statements.

  8 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
 SCHEDULE OF INVESTMENTS                                       OCTOBER 31, 2000
-------------------------------------------------------------------------------
<TABLE>
<CAPTION>
      FACE
     AMOUNT                             SECURITY                                             VALUE
-------------------------------------------------------------------------------------------------------
<S>                 <C>                                                                     <C>
DISCOUNT NOTE -- 2.6%
      $939,000      Student Loan Marketing Discount Note
                      6.45% due 11/1/00 (Identified Cost-- $939,000)                         $  939,000
-------------------------------------------------------------------------------------------------------
                    TOTAL INVESTMENTS -- 100%
                    (Identified Cost-- $40,640,436+)                                        $35,999,917
-------------------------------------------------------------------------------------------------------
</TABLE>

  * Non-income producing security.
  + Aggregate cost for federal income tax is substantially the same.

                       See Notes to Financial Statements.

  9 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders

<PAGE>

-------------------------------------------------------------------------------
Statement of Assets and Liabilities                            October 31, 2000
-------------------------------------------------------------------------------
ASSETS:
     Investments, at value (Cost-- $40,640,436)                    $35,999,917
     Cash                                                                  960
     Receivable for Fund shares sold                                   430,281
     Receivable for open forward foreign currency contract                  11
     Receivable from the Administrator (Note 10)                        44,883
-------------------------------------------------------------------------------
     TOTAL ASSETS                                                   36,476,052
-------------------------------------------------------------------------------
LIABILITIES:
     Payable for securities purchased                                  398,478
     Payable for Fund shares purchased                                   9,415
     Payable for open forward foreign currency contracts                     9
     Distribution fees payable                                          24,580
     Accrued expenses and other liabilities                             90,054
-------------------------------------------------------------------------------
     TOTAL LIABILITIES                                                 522,536
-------------------------------------------------------------------------------
TOTAL NET ASSETS                                                   $35,953,516
-------------------------------------------------------------------------------
NET ASSETS:
     Par value of capital shares                                   $     3,644
     Capital paid in excess of par value                            40,614,613
     Accumulated net investment loss                                    (2,318)
     Accumulated net realized loss from security
      transactions and foreign currencies                              (21,902)
     Net unrealized depreciation of investments
      and foreign currencies                                        (4,640,521)
------------------------------------------------------------------------------
TOTAL NET ASSETS                                                   $35,953,516
------------------------------------------------------------------------------
SHARES OUTSTANDING:
     Class A                                                           859,230
     -------------------------------------------------------------------------
     Class B                                                         1,186,672
     -------------------------------------------------------------------------
     Class L                                                         1,598,042
------------------------------------------------------------------------------
NET ASSET VALUE:
     Class A (and redemption price)                                      $9.88
     -------------------------------------------------------------------------
     Class B *                                                           $9.86
     -------------------------------------------------------------------------
     Class L **                                                          $9.86
------------------------------------------------------------------------------
MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
------------------------------------------------------------------------------
     Class A (net asset value plus 5.26% of net asset value per share)  $10.40
     -------------------------------------------------------------------------
     Class L (net asset value plus 1.01% of net asset value per share)   $9.96
------------------------------------------------------------------------------
 * Redemption  price is NAV of Class B shares reduced by a 5.00% CDSC if shares
   are redeemed less than one year from initial purchase (See Note 2).
** Redemption  price is NAV of Class L shares reduced by a 1.00% CDSC if shares
   are redeemed within the first year of purchase.




                       See Notes to Financial Statements.

  10 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
STATEMENT OF OPERATIONS
-------------------------------------------------------------------------------
FOR THE PERIOD AUGUST 31, 2000 (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000
INVESTMENT INCOME:
     Interest Income                                                $   42,740
-------------------------------------------------------------------------------
EXPENSES:
     Management fees (Note 2)                                           53,492
     Distribution fees (Note 2)                                         46,261
     Custody fees                                                       40,000
     Shareholder communications                                         30,509
     Audit fees                                                         17,667
     Registration fees                                                  10,580
     Legal fees                                                          3,068
     Directors' fees                                                     2,957
     Other                                                               1,814
-------------------------------------------------------------------------------
     TOTAL EXPENSES                                                    206,348
     Less: Aggregate amount waived by the Manager (Note 2)             (43,313)
     Less: Expenses assumed by the Administrator (Note 11)             (44,883)
-------------------------------------------------------------------------------
     NET EXPENSES                                                      118,152
-------------------------------------------------------------------------------
NET INVESTMENT LOSS                                                    (75,412)
-------------------------------------------------------------------------------
REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS (NOTE 3):
     Realized Gain From:
      Security (excluding short-term securities)
        and foreign currency transactions                                2,095
-------------------------------------------------------------------------------
     Decrease in Net Unrealized Depreciation                        (4,640,521)
-------------------------------------------------------------------------------
NET LOSS ON INVESTMENTS                                             (4,638,426)
-------------------------------------------------------------------------------
DECREASE IN NET ASSETS FROM OPERATIONS                             $(4,713,838)
-------------------------------------------------------------------------------





                       See Notes to Financial Statements.


  11 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
STATEMENT OF CHANGES IN NET ASSETS
-------------------------------------------------------------------------------
FOR THE PERIOD AUGUST 31, 2000  (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000
OPERATIONS:
     Net investment loss                                           $   (75,412)
     Net realized gain                                                   2,095
     Decrease in net unrealized depreciation                        (4,640,521)
-------------------------------------------------------------------------------
     DECREASE IN NET ASSETS FROM OPERATIONS                         (4,713,838)
-------------------------------------------------------------------------------
FUND SHARE TRANSACTIONS (NOTE 6):
     Net proceeds from sale of shares                               41,165,480
     Net asset value of shares issued for reinvestment of dividends         --
     Cost of shares reacquired                                        (498,126)
-------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS            40,667,354
-------------------------------------------------------------------------------
INCREASE IN NET ASSETS                                               35,953,516
NET ASSETS:
     Beginning of period                                                     --
-------------------------------------------------------------------------------
     END OF PERIOD*                                                 $35,953,516
-------------------------------------------------------------------------------
* Includes accumulated net investment loss of:                     $    (2,318)
-------------------------------------------------------------------------------



                       See Notes to Financial Statements.


  12 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS
-------------------------------------------------------------------------------

1. SIGNIFICANT ACCOUNTING POLICIES

The Smith Barney Global Biotechnology Fund is a non-diversified  investment fund
of the Smith Barney Sector Series Inc. (the "Company"),  a Maryland corporation.
The Company is registered under the Investment  Company of 1940, as amended,  as
an open-end  management  investment  company and  consists of this Fund and five
other separate  investment  funds:  Smith Barney Financial  Services Fund, Smith
Barney Health Sciences Fund,  Smith Barney  Technology Fund, Smith Barney Global
Media &  Telecommunications  Fund and Smith Barney  Global  Technology  Fund. On
August 31, 2000, the Fund commenced operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed to be  over-the-counter)  and securities for which no sale was reported
on that date are valued at the mean  between the bid and ask prices.  Securities
which are listed or traded on more than one exchange or market are valued at the
quotations  on the exchange or market  determined  to be the primary  market for
such  securities;  (c) securities for which market  quotations are not available
will be valued in good faith at fair market  value by or under the  direction of
the Board of Directors;  (d)  securities  maturing  within 60 days are valued at
cost plus accreted  discount,  or minus amortized  premium,  which  approximates
value;  (e) the accounting  records of the Fund are maintained in U.S.  dollars.
All assets and liabilities denominated in foreign currencies are translated into
U.S.  dollars  based on the rate of exchange  of such  currencies  against  U.S.
dollars on the date of valuation.  Purchases and sales of securities, and income
and expenses are  translated  at the rate of exchange  quoted on the  respective
date that such transactions are recorded.  Differences between income or expense
amounts  recorded  and  collected  or paid are  adjusted  when  reported  by the
custodian;  (f)  interest  income,  adjusted  for  amortization  or premium  and
accretion of discount,  is recorded on an accrual basis;  (g) dividend income is
recorded  on  the  ex-dividend  date;  foreign  dividends  are  recorded  on the
ex-dividend date or as soon as practical after the Fund determines the existence
of a  dividend  declaration  after  exercising  reasonable  due  diligence;  (h)
dividends and  distributions  to  shareholders  are recorded on the  ex-dividend
date;  (i) gains or losses on the sale of securities are calculated by using the
specific  indentification method; (j) direct expenses are charged to each class;
management fees and general  expenses are allocated on the basis of relative net
assets;  (k) the character of income and gains to be distributed  are determined
in  accordance  with  income tax  regulations  which may differ  from  generally
accepted  accounting  principles;  (l) the  Fund  intends  to  comply  with  the
requirements  of the Internal  Revenue Code of 1986,  as amended,  pertaining to
regulated  investment  companies  and to make  distributions  of taxable  income
sufficient to relieve it from substantially all Federal income and excise taxes;
(m) the  character  of income and gains to be  distributed  in  accordance  with
income tax  regulations  which may differ  from  generally  accepted  accounting
principles.  At  October  31,  2000,  reclassifications  were made to the Fund's
capital accounts to reflect permanent book/tax  differences and income and gains
available for distribution under income tax regulations.  Accordingly,  the Fund
reclassified  $49,097,  from  paid in  capital,  $23,997  from  accumulated  net
realized loss and $73,094 to  accumulated  net  investment  loss. Net investment
income,  net realized gains and net assets were not affected by this  adjustment
and (n)  estimates and  assumptions  are required to be made  regarding  assets,
liabilities  and changes in net assets  resulting from operations when financial
statements are prepared. Changes in the economic environment,  financial markets
and any other parameters used in determining  these estimates could cause actual
results to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market rate as an unrealized respectively.

  13 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
-------------------------------------------------------------------------------


2. MANAGEMENT AGREEMENT AND
   OTHER TRANSACTIONS

SSB Citi Fund  Management  LLC  ("SSBC"),  a subsidiary  of Salomon Smith Barney
Holdings  Inc.  ("SSBH"),  which,  in turn,  is a subsidiary  of Citigroup  Inc.
("Citigroup"),  acts as investment  manager to the Fund.  The  management fee is
computed at an annual rate of 0.95% of the  average  daily net assets.  SSBC has
delegated the daily management of the Fund to Citibank N.A., (the "SubAdviser"),
an affiliate of SSBC.  For services  provided to the Fund,  the manager pays the
Subadviser a  subadvisory  fee computed at an annual rate of 0.50% of the Fund's
average daily net assets. The management fees paid amounted to $53,492, of which
$43,313 was voluntarily waived for the period ended October 31, 2000.

Salomon Smith Barney Inc. acts as the Fund's  distributor.  Salomon Smith Barney
Inc.   ("SSB"),   another   subsidiary   of  SSBH,  as  well  as  certain  other
broker-dealers,  continues  to sell Fund shares to the public as a member of the
selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and PFPC Global Fund  Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTC receives fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $2,786 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
-------------------------------------------------------------------
CDSCs                        $  --          $ --      $    1,000
-------------------------------------------------------------------
Sales Charges               $259,000        $ --       $179,000
-------------------------------------------------------------------



Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
-------------------------------------------------------------------
Distribution Plan Fees       $3,349        $18,334      $24,578
-------------------------------------------------------------------

All officers and one Director of the Fund are employees of SSB.

3. INVESTMENTS

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

---------------------------------------------------------------------
Purchases                                            $40,051,165
---------------------------------------------------------------------
Sales                                                 $  351,159
---------------------------------------------------------------------

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

--------------------------------------------------------------------
Gross unrealized appreciation                      $ 1,605,939
Gross unrealized depreciation                       (6,246,458)
--------------------------------------------------------------------
Net unrealized depreciation                        $(4,640,519)
--------------------------------------------------------------------

4. FORWARD FOREIGN CURRENCY CONTRACTS

At October 31, 2000,  the Fund had open forward  foreign  currency  contracts as
described  below.  The Fund bears the market risk that  arises  from  changes in
foreign currency exchange rates. The unrealized loss on the contracts  reflected
in the accompanying financial statements were as follows:

5. OPTION CONTRACTS

                     LOCAL     MARKET   SETTLEMENT    UNREALIZED
FOREIGN CURRENCY   CURRENCY     VALUE      DATE       GAIN (LOSS)
-------------------------------------------------------------------

To Buy:
CHF                 12,859      7,155     11/2/00          11
GBP                  2,243      3,255     11/6/00          (9)
-------------------------------------------------------------------

Net Unrealized Gain
(Loss) on Forward
  Foreign Currency Contracts                                2
-------------------------------------------------------------------




  14 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

Premiums  paid when put or call  options  are  purchased  by the Fund  represent
investments,  which are marked-to-market daily. When a purchased option expires,
the Fund will  realize a loss in the amount of the premium  paid.  When the Fund
enters into a closing  sales  transaction,  the Fund will realize a gain or loss
depending on whether the proceeds from the closing sales transaction are greater
or less than the  premium  paid for the  option.  When the Fund  exercises a put
option, it will realize a gain or loss from the sale of the underlying  security
and the  proceeds  from such sale will be decreased by the amount of the premium
originally paid. When the Fund exercises a call option, the cost of the security
that  the  Fund  purchases  upon  exercise  will  be  increased  by the  premium
originally paid.

At October 31, 2000, the Fund had no open purchased call or put options.

When a Fund writes a call or put option, an amount equal to the premium received
by the Fund is recorded as a liability,  the value of which is  marked-to-market
daily. When a written option expires, the Fund realizes a gain or loss depending
upon  whether  the cost of the closing  transaction  is greater or less than the
premium  originally  received,  without regard to any unrealized gain or loss on
the underlying security, and the liability related to such option is eliminated.
When a written  call option is exercised  the cost of the security  sold will be
decreased  by the  premium  originally  received.  When a written  put option is
exercised, the amount of the premium originally received will reduce the cost of
the security which the Fund purchased upon exercise.  When written index options
are exercised, settlement is made in cash.

The risk associated with purchasing options is limited to the premium originally
paid. The Fund enters into options for hedging  purposes.  The risk in writing a
call  option is that the Fund gives up the  opportunity  to  participate  in any
increase in the price of the underlying  security beyond the exercise price. the
risk in  writing a put option is that the Fund is exposed to the risk of loss if
the market price of the underlying security declines.

At October 31, 2000, the Fund did not write any options.

6. FUTURES CONTRACTS

Initial margin deposits made upon entering into futures contracts are recognized
as assets.  Securities  equal to the initial margin amount are segregated by the
custodian in the name of the broker.  Additional  securities are also segregated
up to the current  market value of the futures  contract.  During the period the
futures contract is open, changes in the value of the contract are recognized as
unrealized  gains or losses by  "marking-to-market"  on a daily basis to reflect
the market  value of the  contract at the end of each day's  trading.  Variation
margin  payments  are  received  or made and  recognized  as assets  due from or
liabilities due to broker, depending upon whether unrealized gains or losses are
incurred.  When the contract is closed, the Fund records a realized gain or loss
equal to the  difference  between  the  proceeds  from (or cost of) the  closing
transactions and the Fund's basis in the contract.

The Fund enters into such  contracts  to hedge a portion of its  portfolio.  The
Fund  bears  the  market  risk  that  arises  from  changes  in the value of the
financial instruments and securities indices (futures contracts).

At October 31, 2000, the Fund had no open futures contracts.

7. REPURCHASE AGREEMENTS

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Fund requires continual  maintenance
of the market  value of the  collateral  (plus  accrued  interest) in amounts at
least equal to the repurchase price.

8. CONCENTRATION OF RISK

The Fund intends to invest at least 80% of its assets in bio-technology  related
investments.  As a result of this concentration  policy,  which is a fundamental
policy of the Fund,  the Fund's  investment  may be subject to greater  risk and
market fluctuation than a fund that invests in securities representing a broader
range of investment alternatives.


  15 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS (CONTINUED)
-------------------------------------------------------------------------------

The Fund's  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S. dollar can  significantly  affect the value of these investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.

9. CAPITAL SHARES

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.





At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:

                             CLASS A       CLASS B         CLASS L
-------------------------------------------------------------------------------
Total Paid-in Capital      $9,580,974    $13,264,512     $17,821,868
-------------------------------------------------------------------------------


10. ASSUMPTION OF EXPENSES

SSBC has voluntarily agreed to pay a portion of the expenses of the Fund for the
period ended October 31, 2000, which amounted to $44,883.

11. CAPITAL LOSS CARRYFORWARD

At October 31, 2000,  the Fund had, for Federal  income tax purposes,  a capital
loss carryforward of approximately  $21,902,  available to offset future capital
gains expiring  October 31, 2008. To the extent that these  carryforward  losses
are used to offset capital  gains,  it is probable that any gains so offset will
not be distributed.



Transactions in shares of each class were as follows:


                                                     AUGUST 31, 2000
                                                (COMMENCEMENT OF OPERATIONS)
                                                    TO OCTOBER 31, 2000
                                              ---------------------------------
                                               SHARES                 AMOUNT
-------------------------------------------------------------------------------
CLASS A
Shares sold                                   865,546            $   9,646,712
Shares issued on reinvestment                      --                      --
Shares reacquired                              (6,316)                 (65,738)
-------------------------------------------------------------------------------
Net Increase                                  859,230            $   9,580,974
-------------------------------------------------------------------------------
CLASS B
Shares sold                                 1,216,537            $  13,558,737
Shares issued on reinvestment                      --                      --
Shares reacquired                             (29,865)                (294,225)
-------------------------------------------------------------------------------
Net Increase                                1,186,672            $  13,264,512
-------------------------------------------------------------------------------
CLASS L
Shares sold                                 1,611,305            $  17,960,031
Shares issued on reinvestment                      --                      --
Shares reacquired                             (13,263)                (138,163)
-------------------------------------------------------------------------------
Net Increase                                1,598,042            $  17,821,868
-------------------------------------------------------------------------------




  16 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>


-------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS
-------------------------------------------------------------------------------

For a share of each class of capital stock from August 31, 2000 (Commencement of
Operations) to October 31, 2000



CLASS A SHARES
-------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD           $11.40
-------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                          (0.04)
   Net realized and unrealized loss             (1.48)
-------------------------------------------------------------------------------
Total Income From Operations                    (1.52)
-------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                           --
   Net realized gain                               --
-------------------------------------------------------------------------------
Total Distributions                                --
-------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                  $9.88
-------------------------------------------------------------------------------
TOTAL RETURN                                    (13.33)%++
-------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)              $8,486
-------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                      1.52 %+
   Net investment loss                          (0.78)%+
-------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                             1%
-------------------------------------------------------------------------------

Note: If Agents of the Fund had not voluntarily  waived a portion of their fees,
      the net investment  income (loss) per share and the ratios would have been
      as follows:
      Net investment loss per share                                  $(0.04)
      RATIOS:
      Expenses to average net assets                                   3.08%+
      Net investment loss to average net assets                       (2.34)%+
-------------------------------------------------------------------------------

Note: The per share amounts were computed using monthly average of shares
      during the period.
  +   Annualized.
  ++  Total return is not annualized, as it may not be representative of
      the total return for the year.




                       See Notes to Financial Statements.


  17 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>
-------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS (CONTINUED)
-------------------------------------------------------------------------------

For a share of each class of capital stock from August 31, 2000 (Commencement of
Operations) to October 31, 2000



CLASS B SHARES
-------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                $11.40
-------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                               (0.05)
   Net realized and unrealized loss                  (1.49)
-------------------------------------------------------------------------------
Total Income From Operations                         (1.54)
-------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                 --
   Net realized gain                                     --
-------------------------------------------------------------------------------
Total Distributions                                      --
-------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                       $9.86
-------------------------------------------------------------------------------
TOTAL RETURN                                        (13.51)%++
-------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                  $11,705
-------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                           2.28%+
   Net investment loss                               (1.51)%+
------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                  1%
------------------------------------------------------------------------------

Note:If Agents of the Fund had not  voluntarily  waived a portion of their fees,
     the net  investment  loss per  share  and the  ratios  would  have  been as
     follows:
     Net investment loss per share                  $(0.05)
     RATIOS:
     Expenses to average net  assets                  3.84%+
     Net  investment  loss to  average  net assets   (3.07)%+
-------------------------------------------------------------------------------

Note: The per share amounts were computed using monthly average of shares
      during the period.
  +   Annualized.
  ++  Total return is not annualized, as it may not be representative of the
      total return for the year.

                       See Notes to Financial Statements.

  18 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>

-------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS (CONTINUED)
-------------------------------------------------------------------------------

For a share of each class of capital stock from August 31, 2000 (Commencement of
Operations) to October 31, 2000



CLASS L SHARES
-------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD               $11.40
-------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                              (0.06)
   Net realized and unrealized loss                 (1.48)
-------------------------------------------------------------------------------
Total Income From Operations                        (1.54)
-------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                               --
   Net realized gain                                   --
-------------------------------------------------------------------------------
Total Distributions                                    --
-------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                      $9.86
-------------------------------------------------------------------------------
TOTAL RETURN                                        (13.51)%++
-------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000S)                   $15,763
-------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                           2.28%+
   Net investment loss                               (1.51)%+
-------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                  1%
-------------------------------------------------------------------------------

Note:  If Agents of the Fund had not  voluntarily  waived a portion of their
       fees,  the net  investment  loss per share and the ratios
       would have been as follows:
       Net investment loss per share                $(0.06)
       RATIOS:
       Expenses to average net assets                 3.84%+
       Net investment loss to average net assets     (3.07)%+
-------------------------------------------------------------------------------

Note: The per share amounts were computed using monthly average of shares
      during the period.
  +   Annualized.
  ++  Total return is not annualized, as it may not be representative of
      the total return for the year.


                       See Notes to Financial Statements.

  19 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders


<PAGE>
--------------------------------------------------------------------------------
INDEPENDENT AUDITORS' REPORT
--------------------------------------------------------------------------------

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTOR SERIES INC.:


We have audited the accompnaying statement of assets and liabilities,  including
the schedule of investments,  of Smith Barney Global Biotechnology Fund of Smith
Barney  Sector  Series Inc. as of October 31,  2000,  the related  statement  of
operations,  the statements of changes in net assets,  and financial  highlights
for the period August 31, 2000 (Commencement of Operations)  through October 31,
2000. These financial statements and financial highlights are the responsibility
of the Fund's  management.  Our responsibility is to express an opinion on these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.

We believe that our audits provide a reasonable basis for our opinion.
In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney  Global  Biotechnology  Fund of Smith  Barney  Sector  Series  Inc. as of
October 31, 2000, the results of its  operations,  the changes in its net assets
and  financial  highlights  for the period  August 31, 2000 through  October 31,
2000, in conformity with accounting  principles generally accepted in the United
States of America.


                                                  /s/ KPMG LLP
                                                  ------------

New York, New York
December 11, 2000




                       See Notes to Financial Statements.

 20 Smith Barney Global Biotechnology Fund | 2000 Annual Report to Shareholders

<PAGE>

SMITH BARNEY
GLOBAL BIOTECHNOLOGY FUND


    DIRECTORS
    Herbert Barg
    Alfred J. Bianchetti
    Martin Brody
    Dwight B. Crane
    Burt N. Dorsett
    Elliot S. Jaffe
    Stephen E. Kaufman
    Joseph J. McCann
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.
    James J. Crisona, Emeritus

    OFFICERS
    Heath B. McLendon
    President and Chief Executive Officer

    Lewis E. Daidone
    Senior Vice President and Treasurer

    Irving P. David
    Controller

    Christina T. Sydor
    Secretary

    INVESTMENT MANAGER
    SSB Citi Fund Management LLC

    INVESTMENT SUBADVISER
    Citibank N.A.

    DISTRIBUTORS
    Salomon Smith Barney Inc.
    PFS Distributors Inc.

    CUSTODIAN
    State Street Bank & Trust Co.

    TRANSFER AGENT
    Citi Fiduciary Trust Company
    125 Broad Street, 11th Floor
    New York, New York 10004

    SUB-TRANSFER AGENT
    PFPC Global Fund Services
    P.O. Box 9699
    Providence, Rhode Island
    02940-9699
<PAGE>


 SMITH BARNEY GLOBAL BIOTECHNOLOGY FUND
-------------------------------------------------------------------------------

                    This report is submitted for general information of the
                    shareholders of Smith Barney Sector Series Inc. -- Smith
                    Barney Global Biotechnolgoy Fund, but it may also be used as
                    sales literature when preceded or accompanied by the current
                    Prospectus, which gives details about charges, expenses,
                    investment objectives and operating policies of the Fund. If
                    used as sales material after January 31, 2001, this report
                    must be accompanied by performance information for the most
                    recently completed calendar quarter.

                    SMITH BARNEY GLOBAL BIOTECHNOLOGY FUND
                    Smith Barney Mutual Funds
                    388 Greenwich Street, MF-2
                    New York, New York 10013

                    For complete  information  on any Smith Barney Mutual Funds,
                    including  management fees and expenses,  call or write your
                    financial  professional  for  a  free  prospectus.  Read  it
                    carefully before you invest or send money.

                    www.smithbarney.com/mutualfunds


                   [SALOMON SMITH BARNEY LOGO]


                   Salomon Smith Barney is a service mark of Salomon
                   Smith Barney Inc.

                   FD02132 12/00

<PAGE>

--------------------------------------------------------------------------------
                                  SMITH BARNEY
                               SECTOR SERIES INC.
                     GLOBAL MEDIA & TELECOMMUNICATIONS FUND
--------------------------------------------------------------------------------
               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000



                                 [LOGO OMITTED]
                                  Smith Barney
                                  Mutual Funds
                 Your Serious Money. Professionally Managed(SM)

--------------------------------------------------------------------------------
             NOT FDIC INSURED o NOT BANK GUARANTEED o MAY LOSE VALUE
--------------------------------------------------------------------------------

<PAGE>

                                                       [Graphic] Research Series

ANNUAL REPORT o OCTOBER 31, 2000
SMITH BARNEY GLOBAL MEDIA &
TELECOMMUNICATIONS FUND

CITIBANK GLOBAL
ASSET MANAGEMENT

Citibank,  N.A.,  through its Citibank Global Asset  Management  division is the
subadviser to the Fund.  Comprising a seasoned  group of investment and research
professionals,  the Fund's  management  team follows a  systematic  and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks  long-term  capital  appreciation.  The Fund normally  invests at
least 80% of its assets in securities of companies  principally  engaged in, but
not limited to, the development,  production,  sale and distribution of goods or
services  used in the  broadcast  and media  industries;  companies  engaged  in
design,  development,  manufacturing,  distribution  or sale  of  communications
services and equipment;  and companies that are involved in supplying  equipment
or  services  to such  companies,  as well as  companies  that  offer  telephone
service, wireless communications, satellite communications, television and movie
programming, broadcasting, and Internet access.

FUND FACTS

FUND INCEPTION
--------------------------------------------------------------------------------
August 31, 2000

             Class A   Class B   Class L
--------------------------------------------------------------------------------
NASDAQ       SMTAX     SMTBX     SGMLX
--------------------------------------------------------------------------------
Inception    8/31/00   8/31/00   8/31/00
--------------------------------------------------------------------------------


SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND*
TOTAL RETURNS OCTOBER 31, 2000

                        WITHOUT SALES CHARGES(1)
                     Class A   Class B   Class L
--------------------------------------------------------------------------------
Since Inception      (8.07)%   (8.16)%   (8.16)%
(August 31, 2000)**
--------------------------------------------------------------------------------

                          WITH SALES CHARGES(2)
                     Class A   Class B   Class L
--------------------------------------------------------------------------------
Since Inception     (12.67)%  (12.75)%   (9.99)%
(August 31, 2000)**
--------------------------------------------------------------------------------
*   Since the Fund focuses its investments on companies involved in the media
    and telecommunications industries, an investment in the Fund may involve a
    greater degree of risk than an investment in other mutual funds with greater
    diversification.

**  Not Annualized

(1) Assumes reinvestment of all dividends and capital gain distributions, if
    any, at net asset value and does not reflect deduction of all applicable
    sales charges with respect to Class A and L shares or the applicable
    contingent deferred sales charges ("CDSC") with respect to Class B and L
    shares.

(2) Assumes reinvestment of all dividends and capital gain distributions, if any
    at net asset value. In addition, Class A and L shares reflect the deduction
    of the maximum initial sales charge of 5.00% and 1.00%, respectively. Class
    B shares reflect the deduction of a 5.00% CDSC, which applies if shares are
    redeemed within one year from purchase. This CDSC declines by 1.00% the
    first year after purchase and thereafter by 1.00% per year until no CDSC is
    incurred. Class L shares also reflect the deduction of 1.00% per year until
    CDSC, which applies if shares are redeemed within the first year of
    purchase.


--------------------------------------------------------------------------------

WHAT'S INSIDE
Your Investment in the Smith Barney
Global Media & Telecommunications Fund ...........     1
Letter from the Chairman .........................     2
Fund at a Glance .................................     3
Shareholder Letter ...............................     4
Schedule of Investments ..........................     8
Statement of Assets and Liabilities ..............    10
Statement of Operations ..........................    11
Statement of Changes in Net Assets ...............    12
Notes to Financial Statements ....................    13
Financial Highlights .............................    17
Independent Auditors' Report .....................    20

                                 [LOGO OMITTED]
                                  Smith Barney
                                  Mutual Funds
                 Your Serious Money. Professionally Managed(SM)

--------------------------------------------------------------------------------
  Investment Poducts: Not FDIC Insured o Not Bank Guaranteed o May Lose Value
--------------------------------------------------------------------------------
<PAGE>

--------------------------------------------------------------------------------
                       YOUR INVESTMENT IN THE SMITH BARNEY
                     GLOBAL MEDIA & TELECOMMUNICATIONS FUND
--------------------------------------------------------------------------------

Led by Citibank  N.A.  through its  Citibank  Global Asset  Management  ("CGAM")
division,  the Fund offers you the  opportunity  to participate in the long-term
growth  potential  of the media and  telecommunications  industries.  The Fund's
management   team   comprises  a  seasoned  group  of  investment  and  research
professionals  who follow a systematic and rigorous approach designed to provide
appropriate exposure to each market sector.

[GRAPHIC]      AN INVESTMENT IN THE FUTURE OF GLOBAL MEDIA AND
               TELECOMMUNICATIONS
               An  investment  in the Fund  represents  an  opportunity  to take
               advantage of the anticipated growth and increasing  importance of
               the  media and  telecommunications  industries.  And  while  this
               sector has seen its fair share of challenges of late, we continue
               to view its long-term prospects favorably.

[GRAPHIC]      DIVERSIFICATION IN A TARGETED SECTOR*
               An investment in the Fund offers investors a way to invest in the
               broad range of companies shaping the media and telecommunications
               industries,  both in the U.S. and abroad.  The Fund's investments
               may  include  companies  in a wide range of  industries,  such as
               broadcasting, media and communications, among others.

[GRAPHIC]      THE BENEFITS OF EXHAUSTIVE FUNDAMENTAL SECURITIES ANALYSIS--
               THE RESEARCH SERIES
               The Research  Series is a selection of Smith Barney  Mutual Funds
               built on a foundation of substantial  buy-side research under the
               direction  of CGAM.  This  series of funds  focuses on  potential
               opportunities from well-defined industries, sectors and trends.

[GRAPHIC]      A COMMITMENT TO MANAGING YOUR SERIOUS MONEY
               SSB Citi Asset  Management  Group ("SSB  Citi"),  the  investment
               management  division of  Citigroup  comprises  Smith Barney Asset
               Management, Salomon Brothers Asset Management and Citibank Global
               Asset Management,  each an organization with extensive investment
               capabilities.

               SSB Citi, as a member of one of the largest financial services
               providers in the world, offers you the benefits of our global
               capabilities. At SSB Citi, you gain access to portfolio
               management delivered professionally. We are proud to offer you,
               the serious investor, a variety of managed solutions.


*Please note that because the Fund invests in a single industry, its shares do
 not represent a complete investment program, and the value of its shares may
 fluctuate more than shares invested in a broader range of industries.


             1 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders

<PAGE>

                            LETTER FROM THE CHAIRMAN

[PHOTO]

HEATH B. MCLENDON
CHAIRMAN


The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks  may be running  out of steam.  At SSB Citi Fund
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.

We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their businesses. Today, with over $398.6 billion in assets under management,(1)
SSB Citi offers  choices and  solutions,  uniting the  distinguished  history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.

A FEW THOUGHTS ON SECTOR INVESTING

Over the past few years,  we have seen how profoundly the  advancements  made in
sectors such as technology and  telecommunications  have  transformed  our daily
lives.  Computer  applications,  wireless  communications  and  biotechnological
discoveries  have created new investment  opportunities  and have changed how we
communicate and how we are  entertained.  The new and developing  sectors of the
economy that are involved in bringing these products,  services and technologies
to life may  offer  exceptional  growth  potential,  and many  investors  should
consider having a portion of their investment portfolios in them.

Although most of us recognize that certain sectors drive the economy, we believe
it is much more difficult to determine  which companies will perform better than
the others over time.  The team of  experienced  professionals  at Citibank N.A.
thoroughly  researches  a broad  range of  companies  within a given  sector and
carefully  analyzes them,  looking to identify those companies that they believe
offer the greatest growth potential over the long term.  Through this exhaustive
and  proprietary  process,  CGAM  seeks  to  offer  an  opportunity  for  you to
participate  in those  companies that it believes are  best-positioned  in their
respective industries.

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.

When you  invest  with SSB Citi  you can do so with  the  confidence  that  your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.

Thank you for your confidence in our investment management approach.


Sincerely,


/s/ Heath B. McLendon
---------------------
Heath B. McLendon
Chairman

November 6, 2000



--------------------------------------------------------------------------------
(1) AS OF OCTOBER 31, 2000. THIS FIGURE REPRESENTS RETAIL, INSTITUTIONAL, MONEY
    AND SEPARATE ACCOUNTS.




             2 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report toShareholders
<PAGE>


--------------------------------------------------------------------------------
SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND AT A GLANCE (UNAUDITED)
--------------------------------------------------------------------------------

GROWTH OF $10,000 INVESTED IN SHARES OF THE
SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND VS. MSCI ALL-WORLD INDEX
--------------------------------------------------------------------------------
        AUGUST 31, 2000 (COMMENCEMENT OF OPERATIONS) -- OCTOBER 31, 2000

       [The following table represents a line chart in the printed piece.]

                                    Class A                 MSCI
                 8/30/00               9500                10000
                 9/30/00               8625                 9469
                 10/31/00              8733                 9312

A $10,000  investment in the Fund made on August 31, 2000 would have declined to
$8,733 with sales charge (as of October 31, 2000).  The graph shows how the fund
compares to its  benchmark for the same period.  The graph  includes the initial
sales charge on the Fund (no comparable charge exists for the index) and assumes
all dividends and distributions are reinvested at Net Asset Value.

*The Morgan Stanley Capital  International  All-World  Index  ("MSCIAll-World")
 represents the performance of 47 markets in both the developed and the emerging
 markets in Africa,  Asia,  Australia,  Europe, North America and South America.
 Please note that an investor cannot invest directly in an index.

--------------------------------------------------------------------------------
                         TOP TEN COMMON STOCK HOLDINGS*
--------------------------------------------------------------------------------

 1. VODAFONE GROUP .................................   8.1%

 2. VERIZON COMMUNICATIONS .........................   6.4

 3. BELLSOUTH CORP. ................................   5.4

 4. SBC COMMUNICATIONS .............................   5.3

 5. DEUTSCHE TELEKOM ...............................   4.1

 6. VIACOM INC. ....................................   3.9

 7. FRANCE TELECOM .................................   3.4

 8. OMNICOM GROUP ..................................   3.3

 9. WALT DISNEY CO. ................................   3.3

10. NIPPON TELEGRAPH & TELEPHONE CO. ...............   3.1

* As a percentage of total investments.


--------------------------------------------------------------------------------
                              PORTFOLIO BREAKDOWN*
--------------------------------------------------------------------------------

       [The following table represents a pie chart in the printed piece.]

                                1.5% Australia
                                6.2% Asia/Pacific
                                2.0% Short-Term
                               34.8% Europe
                               55.5% The Americas


             3 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

DEAR SHAREHOLDER:

We are  pleased to provide  the  inaugural  annual  report for the Smith  Barney
Sector Series Inc.--Smith Barney Global Media & Telecommunications Fund ("Fund")
for the period from August 31, 2000 through  October 31, 2000. In this report we
have  summarized  the periods  prevailing  economic  and market  conditions  and
outlined  our  investment  strategy.  The  information  provided  in this letter
represents  the opinion of the  manager and is not  intended to be a forecast of
future events, a guarantee of future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 9 for a complete list and  percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE

Since its  inception  on August 31, 2000 through  October 31,  2000,  the Fund's
Class A shares,  without and with sales charges  generated  negative  returns of
8.07% and  12.67%,  respectively.  In  comparison,  the Morgan  Stanley  Capital
International  All-World Index ("MSCI All-World  Index")(1)  returned a negative
6.88% for the same period.  Please note that past  performance is not indicative
of future results.

GLOBAL SECTOR INVESTING--THE CGAM PROCESS
Our approach to global sector investing is based on exhaustive  research that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive industry expertise.  Our team looks for analytical consistency through
intensive modeling and strict application of a consistent valuation methodology.

Our management team is made up of a group of high-quality,  seasoned  investment
and  research  professionals  who  follow a  systematic  and  rigorous  strategy
designed  to  provide  the right  exposure  to  various  industries  within  any
particular sector they cover. Our exhaustive  fundamental  research  evaluates a
universe of  businesses  in its global  quest to  identify  and  participate  in
attractive investment opportunities.

                          A THREE-STEP RESEARCH PROCESS
              -----------         ------------        ----------------
              FUNDAMENTAL  ----   QUANTITATIVE  ----  ACTIVE PORTFOLIO
              RESEARCH            RESEARCH            MANAGEMENT
              -----------         ------------        ----------------

We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to  create  portfolios  that we think  should  generate  competitive
returns while helping to moderate risk over time.

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)

----------
(1) THE MSCI ALL-WORLD  INDEX  REPRESENTS THE PERFORMANCE OF MARKETS IN BOTH THE
    DEVELOPED AND THE EMERGING MARKETS IN AFRICA, ASIA, AUSTRALIA, EUROPE, NORTH
    AMERICA  AND SOUTH  AMERICA.  PLEASE  NOTE THAT AN  INVESTOR  CANNOT  INVEST
    DIRECTLY IN AN INDEX.


             4 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders

<PAGE>

Our  fundamental,  proprietary  research  can  add  value  to  active  portfolio
management by providing timely and unbiased information to their decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

o Superior products or services
o Outstanding managements
o Solid balance sheets
o Market leadership
o Leading innovation

--------------------------------------------------------------------------------
                    APPROXIMATELY 200 MILLION PEOPLE, ONLY 3%
                   OF THE WORLD'S POPULATION CURRENTLY USE THE
                  INTERNET. E-COMMERCE IS RISING EXPONENTIALLY,
                    AS THE INTERNET BRINGS ONLINE SHOPPING TO
                    EVERYTHING FROM AUTOMOBILES TO VACATIONS.

              SOURCE: CLINTON ADMINISTRATION AGENDA FOR THE SEATTLE
                    WORLD TRADE ORGANIZATION MEETING, 1999.
--------------------------------------------------------------------------------
In our opinion,  these are the  companies'  strengths that can create real value
and lead to strong  earnings and sales  growth,  which  ultimately  drives stock
prices.

THE CGAM RESEARCH PROCESS DEFINED

We look to differentiate  ourselves from the traditional  approach to investment
management in a number of ways that we think we can add value to the  portfolio.
Our management  style can best be described as  disciplined,  yet flexible.  Our
formidable  global reach and local expertise enable us to nurture research teams
with direct  access to the  regions and  industries  where we do  business.  Our
research  organization  is centered on a  team-approach  to stock  research  and
selection by covering  hundreds of companies and working  closely  together both
within  and  across  industry  teams in a  seamless  fashion  to reach a prudent
consensus.

Each stock analyst builds intensive,  detailed company models from the ground up
that anticipate a particular company's financial  performance.  These models are
based on the company's  competitive  position  within the  industry,  quality of
product offerings,  costs and risks. These intensive models detail the analyst's
assumptions  for  potential  profitability  for the  company  going  forward and
provides some of the necessary  information to forecast company fundamentals and
make stock  recommendations.  The research team looks to ensure  consistency  in
industry  and  accounting  assumptions  and that in turn can  allow  for  better
comparisons of earnings forecasts.

A  common   valuation   framework--based   on  the   Dividend   Discount   Model
("DDM")--allows  for estimation of returns to fair value. Simply stated, the DDM
compares a company's  future  discounted  dividend  stream to its current  stock
price.

We  believe  this  is a  valuable  and  consistent  method  to  provide  current
valuations to securities. The DDM-based valuation process, in our view, provides
a common  yardstick  that helps  analysts  and  portfolio  managers  compare the
relative  valuation


             5 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders


<PAGE>

of one company's stock to another. The equity analyst then combines the DDM
valuation together with other fundamental factors such as earnings surprises to
come up with an investment rating on a company's stock.

THE GLOBAL MEDIA AND TELECOMMUNICATIONS FUND--THE CGAM APPROACH
We believe there are several key trends driving the growth of technology such
as:

o  Deregulation that has continued to erode barriers to entry and stimulating
   competition on a global scale;

o  Technological advances that have rapidly improved the price-performance of
   and demand for communications networks;

o  The recent explosion of the wireless and Internet industries due in large
   part to strong demand for worldwide "anytime, anywhere" connectivity;

o  Distribution of a wide range of new services and revenue opportunities
   requiring media content and data communications; and

o  Industry-wide consolidation due to a need for economies of scale and global
   reach.

--------------------------------------------------------------------------------
                     IN THE YEARS AHEAD, WIRELESS USERS MAY
                    REPRESENT ONE OF THE BIGGEST SOURCES OF
                           TELECOMMUNICATIONS GROWTH.
--------------------------------------------------------------------------------

Our technology  team believes that our view of the media and  telecommunications
industries  differs from many investment  professionals.  The two themes we draw
from are:

o  GLOBAL COVERAGE AND LOCAL PRESENCE. The team looks to provide timely insights
   regarding cross-border  consolidation and emerging technologies.  The team is
   confident that their extensive  research allows them to clearly  evaluate the
   viability of companies' plans to expand internationally.

o  CONSISTENT, LONG-TERM FORECASTS. The team believes that the lines between the
   media,   telecommunications  and  technology  industries  are  becoming  less
   blurring.  The team also holds the view that "traditional"  valuation methods
   used in evaluating  the media and  telecommunications  industries do not take
   into consideration  differing  accounting standards and stages of development
   or market potential.

GLOBAL MEDIA & TELECOMMUNICATIONS SECTOR UPDATE
The  worldwide  media sector,  in our view,  has reached  appropriate  valuation
levels after recent  declines.  Advertising  expenditures  continues at a robust
pace,  although  the rate of  growth is  expected  to slow down in line with the
slowing growth of the U.S. economy. European advertising growth is witnessing an
exceptional year with growth rates of approximately 18% in France,  15% in Italy
and double-digit growth in most European countries.

During the period,  corporate activity in the sector remained strong, as seen by
the highly visible deals between  America Online and Time Warner,  Fox and Chris
Craft,  WWP and Young and Rubicam,  News Corporation and Gemstar and Vivendi and
Universal. We anticipate that corporate consolidation activity may also continue
in radio and satellite television.

Intense competition  continues to pressure the long distance  telecommunications
sector. The largest U.S. carriers,  AT&T, WorldCom, and Sprint all significantly
reduced their outlooks during the past month to reflect severe pricing  pressure
and market  share  losses.  In our  opinion,  the key  drivers  impacting  their
businesses  were new  entrants,  new  technology,  and a migration of traffic to
wireless  networks.  These  competitive  pressures  are affecting not only their
long-distance  voice  business,  but  also  their

             6 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

data and  Internet  backbone  businesses  where  growth  is  slowing.  For these
reasons,  we continue  to favor the local  telephone  companies  such as Verizon
Communications,  BellSouth Corp., SBC Communications,  and Alltel Corp. We think
the local  telephone  companies  that  have more  stable  and  defendable  local
businesses are beginning to take market share from the long distance  operators,
and are  seeing  solid  growth  in  their  wireless  operations  due to  overall
acceleration in U.S. wireless penetration.

The Fund is presently  slightly  overweight in the advertising  industry through
its holdings in Omnicom and Interpublic  Group.  Although  Internet  advertising
budgets have recently been cut, we believe that these two companies  have enough
"traditional"   advertising   pipeline  and  future  prospects  to  warrant  our
investment.  We  are  underweight  telecommunications  firms  and  broadcasters,
although  within  this  underweight  we  see  good  opportunities  in  satellite
broadcasting  through General Motors' Hughes Electronics  subsidiary,  which has
been mentioned as a potential  acquisition  target for News Corporation,  Rupert
Murdoch's Australian media firm.

Also in the telecommunications  space, we are positive on NTT DoCoMo Inc., whose
"i-mode"  wireless  protocol has high market share in Japan, and the possibility
of export to other markets.

Although we look to identify those companies held in the Fund through  bottom-up
fundamental research and stock selection, the overall industry mix is consistent
with the top-down strategic industry themes that we use for estimate forecasting
and rating formulation.  Because the telecommunications  sector is going through
many  changes and  deregulation,  we  carefully  monitor the Fund's  holdings to
reflect any changes that may have an impact on performance.

--------------------------------------------------------------------------------
                      THE MANAGEMENT OF OUR SECTOR FUNDS IS
                     DRIVEN BY OUR ANALYST RECOMMENDATIONS,
                    LONG-TERM EARNINGS AND EARNINGS MOMENTUM
                     FACTORS THAT FORM THE BASIS OF EXPECTED
                     FUTURE RETURNS WITHIN ANY GIVEN SECTOR.
--------------------------------------------------------------------------------

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT
The  management  of the  sector  funds is  driven  by  analyst  recommendations,
long-term earnings and earnings momentum which form the basis of expected future
returns within any given sector.  These expected returns,  coupled with detailed
risk  forecasts,  determine  what  holdings  will be  selected.  In building and
maintaining  the Fund's  portfolio,  we look to avoid a high  risk-to-return  on
their investments and carefully monitor sector  performance,  constantly looking
for any material changes and/or developments.

Thank you for  investing in the Smith Barney Sector  Series  Inc.--Smith  Barney
Global Media &  Telecommunications  Fund.  We look forward to helping you pursue
your financial goals in the years ahead.

Sincerely,


The Investment Team at
Citibank N.A.

NOVEMBER 7, 2000


             7 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS                                         OCTOBER 31, 2000
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
     SHARES                               SECURITY                                       VALUE
====================================================================================================
COMMON STOCK -- 97.9%
AUSTRALIA -- 1.5%
<S>      <C>        <C>                                                                  <C>
         14,427     News Corp. (Media)                                                   $129,374
----------------------------------------------------------------------------------------------------
BRAZIL -- 0.6%
          1,000     Telemig Celular Participacoes S.A. (Telecommunication Services)        52,500
----------------------------------------------------------------------------------------------------
FINLAND -- 0.8%
          3,272     Sonera Oyj (Telecommunication Services)                                72,081
----------------------------------------------------------------------------------------------------
FRANCE -- 4.0%
            389     Canal Plus (Media)                                                     56,283
          2,853     France Telecom S.A. (Telecommunication Services)                      298,274
----------------------------------------------------------------------------------------------------
                                                                                          354,557
----------------------------------------------------------------------------------------------------
GERMANY  -- 4.1%
          9,487     Deutsche Telekom AG (Telecommunication Services)                      356,242
----------------------------------------------------------------------------------------------------
HONG KONG -- 1.7%
         71,000     Pacific Century* (Telecommunication Services)                          54,622
        144,000     South China Morning Post (Media)                                       98,782
----------------------------------------------------------------------------------------------------
                                                                                          153,404
----------------------------------------------------------------------------------------------------
ITALY -- 5.0%
         17,241     Olivetti S.p.A. (Telecommunication Services)                           52,232
         14,803     Telecom Italia S.P.A. (Telecommunication Services)                    171,469
         24,791     T.I.M. S.p.A. (Telecommunication Services)                            210,797
----------------------------------------------------------------------------------------------------
                                                                                          434,498
----------------------------------------------------------------------------------------------------
JAPAN -- 4.5%
             30     Nippon Telegraph & Telephone Co.* (Telecommunication Services)        273,015
              5     NTT DoCoMo, Inc. (Telecommunication Services)                         123,264
----------------------------------------------------------------------------------------------------
                                                                                          396,279
----------------------------------------------------------------------------------------------------
MEXICO -- 1.8%
         59,403     Grupo Televisa* (Media)                                               160,893
----------------------------------------------------------------------------------------------------
NETHERLANDS -- 0.7%
          2,920     KON NV (Telecommunication Services)                                    59,148
----------------------------------------------------------------------------------------------------
SPAIN -- 4.2%
         4,154      Sogecable, S.A.* (Media)                                              101,522
        13,977      Telefonica, S.A. (Telecommunication Services)                         266,514
----------------------------------------------------------------------------------------------------
                                                                                          368,036
----------------------------------------------------------------------------------------------------
UNITED STATES -- 53.7%
          8,255     AT&T Corp. (Telecommunication Services)                               191,413
          4,336     AT&T Corp.-- Liberty Media Corporation* (Media)                        78,048
          5,182     AT&T Wireless Group* (Telecommunication Services)                     129,226
          1,942     ALLTEL Corp. (Telecommunication Services)                             125,138
          9,814     Bellsouth Corp. (Telecommunication Services)                          474,139
          6,596     GM Corporation Cl. H* (Communications Equipment)                      213,710
          6,293     Interpublic Group of Companies, Inc. (Media)                          270,206
            619     Level 3 Communications, Inc.* (Telecommunication Services)             29,519
          3,072     New York Times Co. (Media)                                            112,896
          3,209     Nextel Communications Inc.* (Telecommunication Services)              123,346
</TABLE>


                       SEE NOTES TO FINANCIAL STATEMENTS.

             8 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SCHEDULE OF INVESTMENTS (CONTINUED)                             OCTOBER 31, 2000
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
     SHARES                               SECURITY                                       VALUE
==========================================================================================================
UNITED STATES -- 53.7% (CONTINUED)
<S>       <C>       <C>                                                                       <C>
          3,126     Omnicom Group (Media)                                                     $  288,373
          4,885     Qwest Communications International Inc.* (Telecommunication Services)        237,533
          8,029     SBC Communications Inc. (Telecommunication Services)                         463,173
          2,073     Scripps Co. (E.W.) -- Cl. A (Media)                                          121,141
          1,925     Sprint PCS* (Telecommunication Services)                                      73,391
          2,862     Time Warner Inc. (Media)                                                     217,254
          3,587     Univision Communications Inc.* (Media)                                       137,203
          9,721     Verizon Communications (Telecommunication Services)                          561,995
          6,067     Viacom Inc.* (Media)                                                         345,061
          8,008     Walt Disney Co. (Media)                                                      286,787
          9,050     Worldcom Inc.* (Telecommunication Services)                                  214,937
----------------------------------------------------------------------------------------------------------
                                                                                               4,694,489
----------------------------------------------------------------------------------------------------------
UNITED KINGDOM -- 15.3%
        12,001      British Sky Broadcast (Media)                                                173,258
        16,295      British Telecommunications Plc. (Telecommunication Services)                 191,037
        22,509      Carlton Communications (Media)                                               181,260
         4,231      Reuters Group (Media)                                                         82,385
       170,592      Vodafone Group Plc. (Telecommunication Services)                             709,764
----------------------------------------------------------------------------------------------------------
                                                                                               1,337,704
----------------------------------------------------------------------------------------------------------
                    TOTAL COMMON STOCK
                    (Identified Cost -- $9,151,128)                                            8,569,205
==========================================================================================================

      FACE
     AMOUNT                                 SECURITY                                             VALUE
==========================================================================================================
DISCOUNT NOTE -- 2.1%
      $180,000      Student Loan Marketing Discount Note,
                    6.45% due 11/01/00 (Identified Cost -- $180,000)                             180,000
==========================================================================================================
                    TOTAL INVESTMENTS -- 100%
                    (Identified Cost -- $9,331,128+)                                          $8,749,205
==========================================================================================================
  *  NON-INCOME PRODUCING SECURITY.
  + AGGREGATE COST FOR FEDERAL INCOME TAXES IS SUBSTANTIALLY THE SAME.
</TABLE>



                       SEE NOTES TO FINANCIAL STATEMENTS.

             9 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF ASSETS AND LIABILITIES                             OCTOBER 31, 2000
--------------------------------------------------------------------------------

<TABLE>
<S>                                                                                   <C>
ASSETS:
     Investments, at value (Cost -- $9,331,128)                                       $  8,749,205
     Cash                                                                                      439
     Receivable for Fund shares sold                                                        75,876
     Receivable from Sub-Administrator (Note 10)                                            62,120
     Receivable for securities sold                                                         11,327
     Receivable for open forward foreign currency contracts (Note 4)                            25
     Dividends and interest receivable                                                      11,946
--------------------------------------------------------------------------------------------------------
     TOTAL ASSETS                                                                        8,910,938
--------------------------------------------------------------------------------------------------------
LIABILITIES:
     Payable for securities purchased                                                       78,699
     Payable for Fund shares purchased                                                       2,727
     Distribution fees payable                                                               6,113
     Payable for open forward foreign currency contracts (Note 4)                               39
     Accrued expenses and other liabilities                                                 62,165
--------------------------------------------------------------------------------------------------------
     TOTAL LIABILITIES                                                                     149,743
--------------------------------------------------------------------------------------------------------
TOTAL NET ASSETS                                                                      $  8,761,195
========================================================================================================
NET ASSETS:
     Par value of capital shares                                                      $        836
     Capital paid in excess of par value                                                 9,361,069
     Undistributed net investment income                                                    35,621
     Accumulated net realized loss from security transactions and foreign currencies       (54,355)
     Net unrealized depreciation of investments                                           (581,976)
--------------------------------------------------------------------------------------------------------
TOTAL NET ASSETS                                                                      $  8,761,195
========================================================================================================
SHARES OUTSTANDING:
     Class A                                                                               118,057
     ---------------------------------------------------------------------------------------------------
     Class B                                                                               497,979
     ---------------------------------------------------------------------------------------------------
     Class L                                                                               220,895
     ---------------------------------------------------------------------------------------------------

NET ASSET VALUE:
     Class A (and redemption price)                                                         $10.48
     ---------------------------------------------------------------------------------------------------
     Class B *                                                                              $10.47
     ---------------------------------------------------------------------------------------------------
     Class L **                                                                             $10.47
     ---------------------------------------------------------------------------------------------------

MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
     Class A (net asset value plus 5.26% of net asset value per share)                      $11.03
     ---------------------------------------------------------------------------------------------------
     Class L (net asset value plus 1.01% of net asset value per share)                      $10.58
========================================================================================================
</TABLE>

  * REDEMPTION  PRICE IS NAV OF CLASS B SHARES REDUCED BY A 5.00% CDSC IF SHARES
    ARE REDEEMED LESS THAN ONE YEAR FROM INITIAL PURCHASE (SEE NOTE 2).
 ** REDEMPTION  PRICE IS NAV OF CLASS L SHARES REDUCED BY A 1.00% CDSC IF SHARES
    ARE REDEEMED WITHIN THE FIRST YEAR OF PURCHASE.




                       SEE NOTES TO FINANCIAL STATEMENTS.

            10 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
STATEMENT OF OPERATIONS
--------------------------------------------------------------------------------

FOR THE PERIOD AUGUST 31, 2000 (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000

<TABLE>
<S>                                                                                        <C>
INVESTMENT INCOME:
     Dividends                                                                             $    13,350
     Interest                                                                                   11,526
     Less: Foreign withholding tax                                                                (107)
---------------------------------------------------------------------------------------------------------
     TOTAL INVESTMENT INCOME                                                                    24,769
---------------------------------------------------------------------------------------------------------
EXPENSES:
     Management fees (Note 2)                                                                   10,434
     Distribution fees (Note 2)                                                                 11,764
     Custody fees                                                                               20,750
     Registration fees                                                                           2,584
     Shareholder communications                                                                 30,509
     Audit fees                                                                                 17,667
     Legal fees                                                                                  3,068
     Directors' fees                                                                             2,957
     Other                                                                                       1,314
---------------------------------------------------------------------------------------------------------
     TOTAL EXPENSES                                                                            101,047
     Less: expenses assumed by the Sub-Administrator (Note 10)                                 (62,120)
     Less: aggregate amount waived by the Manager (Note 2)                                     (10,434)
---------------------------------------------------------------------------------------------------------
     NET EXPENSES                                                                               28,493
---------------------------------------------------------------------------------------------------------
NET INVESTMENT LOSS                                                                             (3,724)
---------------------------------------------------------------------------------------------------------
REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS (NOTE 3):
     Realized Loss From:
        Security (excluding short-term securities) and foreign currency transactions           (26,774)
---------------------------------------------------------------------------------------------------------
     Increase in Net Unrealized Depreciation                                                  (581,976)
---------------------------------------------------------------------------------------------------------
NET LOSS ON INVESTMENTS                                                                       (608,750)
---------------------------------------------------------------------------------------------------------
DECREASE IN NET ASSETS FROM OPERATIONS                                                     $  (612,474)
==========================================================================================================
</TABLE>


                       SEE NOTES TO FINANCIAL STATEMENTS.

            11 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>


--------------------------------------------------------------------------------
STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------

FOR THE PERIOD AUGUST 31, 2000 (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000

<TABLE>
<S>                                                                        <C>
OPERATIONS:
     Net investment loss                                                   $   (3,724)
     Net realized loss                                                        (26,774)
     Increase in net unrealized depreciation                                 (581,976)
---------------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM OPERATIONS                                  (612,474)
---------------------------------------------------------------------------------------

FUND SHARE TRANSACTIONS (NOTE 9):
     Net proceeds from sale of shares                                       9,538,770
     Net asset value of shares issued for reinvestment of dividends                --
     Cost of shares reacquired                                               (165,101)
---------------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS                    9,373,669
---------------------------------------------------------------------------------------

INCREASE IN NET ASSETS                                                      8,761,195

NET ASSETS:
     Beginning of period                                                           --
---------------------------------------------------------------------------------------
     END OF PERIOD*                                                        $8,761,195
=======================================================================================
* Includes undistributed net investment income:                              $ 35,621
=======================================================================================
</TABLE>




                       SEE NOTES TO FINANCIAL STATEMENTS.

            12 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1.  Significant Accounting Policies

The Smith Barney  Global Media &  Telecommunications  Fund is a  non-diversified
investment  fund of the Smith  Barney  Sector  Series Inc.  (the  "Company"),  a
Maryland corporation.  The Company is registered under the Investment Company of
1940, as amended, as an open-end  management  investment company and consists of
this Fund and five other  separate  investment  funds:  Smith  Barney  Financial
Services Fund, Smith Barney Health Sciences Fund, Smith Barney  Technology Fund,
Smith Barney Global Biotechnology Fund, and Smith Barney Global Technology Fund.
On August 31, 2000, the Fund commenced operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed to be  over-the-counter)  and securities for which no sale was reported
on that date are valued at the mean  between the bid and ask prices.  Securities
which are listed or traded on more than one exchange or market are valued at the
quotations  on the exchange or market  determined  to be the primary  market for
such  securities;  (c) securities for which market  quotations are not available
will be valued in good faith at fair market  value by or under the  direction of
the Board of Directors;  (d)  securities  maturing  within 60 days are valued at
cost plus accreted  discount,  or minus amortized  premium,  which  approximates
value;  (e) the accounting  records of the Fund are maintained in U.S.  dollars.
All assets and liabilities denominated in foreign currencies are translated into
U.S.  dollars  based on the rate of exchange  of such  currencies  against  U.S.
dollars on the date of valuation.  Purchases and sales of securities, and income
and expenses are  translated  at the rate of exchange  quoted on the  respective
date that such transactions are recorded.  Differences between income or expense
amounts  recorded  and  collected  or paid are  adjusted  when  reported  by the
custodian;  (f)  interest  income,  adjusted  for  amortization  or premium  and
accretion of discount,  is recorded on an accrual basis;  (g) dividend income is
recorded  on  the  ex-dividend  date;  foreign  dividends  are  recorded  on the
ex-dividend date or as soon as practical after the Fund determines the existence
of a  dividend  declaration  after  exercising  reasonable  due  diligence;  (h)
dividends and  distributions  to  shareholders  are recorded on the  ex-dividend
date;  (i) gains or losses on the sale of securities are calculated by using the
specific  identification  method; (j) direct expenses are charged to each class;
management fees and general  expenses are allocated on the basis of relative net
assets;  (k) the character of income and gains to be distributed  are determined
in  accordance  with  income tax  regulations  which may differ  from  generally
accepted  accounting  principles;  (l) the  Fund  intends  to  comply  with  the
requirements  of the Internal  Revenue Code of 1986,  as amended,  pertaining to
regulated  investment  companies  and to make  distributions  of taxable  income
sufficient to relieve it from substantially all Federal income and excise taxes;
(m) the  character  of income and gains to be  distributed  in  accordance  with
income tax  regulations  which may differ  from  generally  accepted  accounting
principles.  At  October  31,  2000,  reclassifications  were made to the Fund's
capital accounts to reflect permanent book/tax  differences and income and gains
available for distribution under income tax regulations.  Accordingly,  the Fund
reclassified $11,764 from paid in capital, $17,210 from accumulated net realized
loss and $28,974 to undistributed net investment  income. Net investment income,
net realized gains and net assets were not affected by this adjustment;  and (n)
estimates and assumptions are required to be made regarding assets,  liabilities
and changes in net assets  resulting from operations  when financial  statements
are prepared.  Changes in the economic  environment,  financial  markets and any
other parameters used in determining  these estimates could cause actual results
to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market rate as an unrealized respectively.



            13 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

2.  Management Agreement and
    Other Transactions

SSB Citi Fund  Management  LLC  ("SSBC"),  a subsidiary  of Salomon Smith Barney
Holdings  Inc.  ("SSBH"),  which,  in turn,  is a subsidiary  of Citigroup  Inc.
("Citigroup"),  acts as investment  manager to the Fund.  The  management fee is
computed at an annual rate of 0.80% of the  average  daily net assets.  SSBC has
delegated the daily  management of the Fund to Citibank N.A., (the  SubAdviser),
an affiliate of SSBC.  For services  provided to the Fund,  the manager pays the
Subadviser a  subadvisory  fee computed at an annual rate of 0.50% of the Fund's
average daily net assets.  The management fees paid amounted to $10,434,  all of
which was waived for the period ended October 31, 2000.

Salomon Smith Barney Inc. acts as the Fund's  distributor.  Salomon Smith Barney
Inc.   ("SSB"),   another   subsidiary   of  SSBH,  as  well  as  certain  other
broker-dealers,  continues  to sell Fund shares to the public as a member of the
selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and PFPC Global Fund  Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTC receives fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $650 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
================================================================================
CDSCs                        $  --          $ --        $  --
--------------------------------------------------------------------------------
Sales Charges                $34,000        $ --        $25,000
================================================================================

Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
================================================================================
Distribution Plan Fees        $426         $7,901       $3,437
================================================================================

All officers and one Director of the Fund are employees of SSB.

3.  Investments

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

================================================================================
Purchases                                                            $9,398,734
--------------------------------------------------------------------------------
Sales                                                                $  224,605
================================================================================

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

================================================================================
Gross unrealized appreciation                                        $  447,815
Gross unrealized depreciation                                        (1,029,791)
--------------------------------------------------------------------------------
Net unrealized depreciation                                          $ (581,976)
================================================================================







4. Forward Foreign Currency Contracts

At October 31, 2000,  the Fund had open forward  foreign  currency  contracts as
described  below.  The Fund bears the market risk that  arises  from  changes in
foreign currency exchange rates. The unrealized loss on the contracts  reflected
in the accompanying financial statements were as follows:

                         LOCAL     MARKET   SETTLEMENT    UNREALIZED
FOREIGN CURRENCY       CURRENCY     VALUE      DATE        GAIN/LOSS
================================================================================
TO BUY
Euro                    10,240     $ 8,691    11/3/00       $  25
Pound Sterling          10,093     $14,646    11/6/00         (39)
--------------------------------------------------------------------------------
Net Unrealized Loss
  on Forward Foreign
  Currency Contracts                                         $(14)
================================================================================


            14 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

5. Option Contracts

Premiums  paid when put or call  options  are  purchased  by the Fund  represent
investments,  which are marked-to-market daily. When a purchased option expires,
the Fund will  realize a loss in the amount of the premium  paid.  When the Fund
enters into a closing sales  transaction,  the portfolio  will realize a gain or
loss  depending on whether the proceeds from the closing sales  transaction  are
greater or less than the premium paid for the option.  When the Fund exercises a
put  option,  it will  realize  a gain or loss  from the sale of the  underlying
security and the proceeds  from such sale will be decreased by the amount of the
premium  originally paid. When the Fund exercises a call option, the cost of the
security that the Fund  purchases upon exercise will be increased by the premium
originally paid.

At October 31, 2000, the Fund had no open purchased call or put options.

When a Fund writes a call or put option, an amount equal to the premium received
by the Fund is recorded as a liability,  the value of which is  marked-to-market
daily.  When a written option  expires,  the Fund realizes a gain. When the Fund
enters into a closing  purchase  transaction,  the Fund  realizes a gain or loss
depending  upon whether the cost of the closing  transaction  is greater or less
than the premium originally  received,  without regard to any unrealized gain or
loss on the  underlying  security,  and the liability  related to such option is
eliminated.  When a written  call option is  exercised  the cost of the security
sold will be decreased by the premium  originally  received.  When a written put
option is exercised,  the amount of the premium originally  received will reduce
the cost of the security  which the  Portfolio  purchased  upon  exercise.  When
written index options are exercised, settlement is made in cash.

The risk associated with purchasing options is limited to the premium originally
paid. The Fund enters into options for hedging  purposes.  The risk in writing a
call  option is that the Fund gives up the  opportunity  to  participate  in any
increase in the price of the underlying  security beyond the exercise price. The
risk in  writing a put option is that the Fund is exposed to the risk of loss if
the market price of the underlying security declines.

During the period ended October 31, 2000, the Fund did not write any options.

6. Futures Contracts

Initial margin deposits made upon entering into futures contracts are recognized
as assets.  Securities  equal to the initial margin amount are segregated by the
custodian in the name of the broker.  Additional  securities are also segregated
up to the current  market value of the futures  contract.  During the period the
futures contract is open, changes in the value of the contract are recognized as
unrealized  gains or losses by  "marking-to-market"  on a daily basis to reflect
the market  value of the  contract at the end of each day's  trading.  Variation
margin  payments  are  received  or made and  recognized  as assets  due from or
liabilities due to broker, depending upon whether unrealized gains or losses are
incurred.  When the contract is closed, the Fund records a realized gain or loss
equal to the  difference  between  the  proceeds  from (or cost of) the  closing
transactions and the Fund's basis in the contract.

The Fund enters into such  contracts  to hedge a portion of its  portfolio.  The
Fund  bears  the  market  risk  that  arises  from  changes  in the value of the
financial instruments and securities indices (futures contracts).

At October 31, 2000, the Fund had no open futures contracts.

7. Repurchase Agreements

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Fund requires continual  maintenance
of the market  value of the  collateral  (plus  accrued  interest) in amounts at
least equal to the repurchase price.

8. Concentration of Risks

The  Fund   intends   to  invest  at  least  80%  of  its   assets  in  media  &
telecommunications  related  investments.  As a  result  of  this  concentration
policy,  which is a fundamental policy of the


            15 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

Fund,  the  Fund's  investment  may  be  subject  to  greater  risk  and  market
fluctuation than a fund that invests in securities  representing a broader range
of investment alternatives.

The Funds'  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S.  dollar can  significantly  affect the value of the  investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.

In addition to the risks described  above,  risks may arise from forward foreign
currency contracts with respect to the potential  inability of counterparties to
meet the terms of their contracts.

9.  Capital Shares

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.

At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:

                                CLASS A          CLASS B          CLASS L
================================================================================
Total Paid-in Capital         $1,311,991       $5,591,667       $2,470,011
================================================================================

10. Assumption of Expenses

SSBH has voluntarily agreed to pay a portion of the expenses of the Fund for the
period ended October 31, 2000, which amounted to $62,120.

11. Capital Loss Carryforward

At October 31, 2000,  the Fund had, for Federal  income tax purposes,  a capital
loss carryforward of approximately  $54,076,  available to offset future capital
gains expiring  October 31, 2008. To the extent that these  carryforward  losses
are used to offset capital  gains,  it is probable that any gains so offset will
not be distributed.



Transactions in shares of each class were as follows:

                                                         AUGUST 31, 2000
                                                  (COMMENCEMENT OF OPERATIONS)
                                                       TO OCTOBER 31, 2000
                                               ---------------------------------
                                                SHARES                 AMOUNT
================================================================================
CLASS A
Shares sold                                     119,238             $ 1,323,986
Shares issued on reinvestment                        --                      --
Shares reacquired                                (1,181)                (11,995)
--------------------------------------------------------------------------------
Net Increase                                    118,057             $ 1,311,991
================================================================================
CLASS B
Shares sold                                     509,391             $ 5,706,545
Shares issued on reinvestment                        --                      --
Shares reacquired                               (11,412)               (114,878)
--------------------------------------------------------------------------------
Net Increase                                    497,979             $ 5,591,667
================================================================================
CLASS L
Shares sold                                     224,522             $ 2,508,239
Shares issued on reinvestment                        --                      --
Shares reacquired                                (3,627)                (38,228)
--------------------------------------------------------------------------------
Net Increase                                    220,895             $ 2,470,011
================================================================================



            16 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS A SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.09)
   Net realized and unrealized loss                                   (0.83)
--------------------------------------------------------------------------------
Total Income From Operations                                          (0.92)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                 --
   Net realized gain                                                     --
--------------------------------------------------------------------------------
Total Distributions                                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                       $10.48
--------------------------------------------------------------------------------
TOTAL RETURN                                                          (8.07)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                    $1,237
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            1.52%+
   Net investment loss                                                 0.35%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                                   3%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY  WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT  INCOME (LOSS) PER SHARE AND THE RATIOS WOULD HAVE BEEN
      AS FOLLOWS:

      Net investment loss per share                                  $(0.09)
      RATIOS:
      Expenses to average net assets                                   7.08%+
      Net investment loss to average net assets                       (5.21)%+
================================================================================
NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE OF SHARES
      DURING THE PERIOD.
  +  ANNUALIZED.
  ++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF
     THE TOTAL RETURN FOR THE YEAR.






                       SEE NOTES TO FINANCIAL STATEMENTS.

            17 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS B SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.10)
   Net realized and unrealized loss                                   (0.83)
--------------------------------------------------------------------------------
Total Income From Operations                                          (0.93)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                 --
   Net realized gain                                                     --
--------------------------------------------------------------------------------
Total Distributions                                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                       $10.47
--------------------------------------------------------------------------------
TOTAL RETURN                                                          (8.16)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                    $5,212
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            2.29%+
   Net investment loss                                                (0.36)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                                   3%
================================================================================
NOTE: IF AGENTS OF THE FUND HAD NOT  VOLUNTARILY  WAIVED A PORTION OF THEIR
      FEES, THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN
      AS FOLLOWS:

      Net investment loss per share                                  $(0.10)
      RATIOS:
      Expenses to average net assets                                   7.85%+
      Net investment loss to average net assets                       (5.92)%+
================================================================================
NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE OF SHARES
      DURING THE PERIOD.
   + ANNUALIZED.
  ++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF
     THE TOTAL RETURN FOR THE YEAR.




                       SEE NOTES TO FINANCIAL STATEMENTS.

            18 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS L SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                                 $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                                (0.10)
   Net realized and unrealized loss                                   (0.83)
--------------------------------------------------------------------------------
Total Income From Operations                                          (0.93)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                                 --
   Net realized gain                                                     --
--------------------------------------------------------------------------------
Total Distributions                                                      --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                       $10.47
--------------------------------------------------------------------------------
TOTAL RETURN                                                          (8.16)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                                    $2,312
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                            2.28%+
   Net investment loss                                                (0.40)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                                   3%
================================================================================
NOTE: IF AGENTS OF THE FUND HAD NOT  VOLUNTARILY  WAIVED A PORTION OF THEIR
      FEES, THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN
      AS FOLLOWS:

     Net investment loss per share                                   $(0.10)
     RATIOS:
     Expenses to average net assets                                    7.85%+
     Net investment loss to average net assets                        (5.96)%+
================================================================================
NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE OF SHARES
      DURING THE PERIOD.
   + ANNUALIZED.
  ++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF
     THE TOTAL RETURN FOR THE YEAR.






                       SEE NOTES TO FINANCIAL STATEMENTS.

            19 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
INDEPENDENT AUDITORS' REPORT
--------------------------------------------------------------------------------

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTOR SERIES INC.:

We have audited the accompanying statement of assets and liabilities,  including
the schedule of investments,  of Smith Barney Global Media &  Telecommunications
Fund of Smith  Barney  Sector  Series Inc. as of October 31,  2000,  the related
statement of  operations,  the statements of changes in net assets and financial
highlights for the period August 31, 2000  (Commencement of Operations)  through
October 31, 2000.  These financial  statements and financial  highlights are the
responsibility  of the Fund's  management.  Our  responsibility is to express an
opinion on these  financial  statements  and financial  highlights  based on our
audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney  Global Media &  Telecommunications  Fund of Smith Barney  Sector  Series
Inc., as of October 31, 2000, the results of its operations,  the changes in its
net assets and  financial  highlights  for the period  August 31,  2000  through
October 31, 2000, in conformity with accounting  prin`ciples  generally accepted
in the United States of America.


/s/ KPMG LLP
--------------------

New York, New York
December 11, 2000




            20 SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND |
                       2000 Annual Report to Shareholders
<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY
GLOBAL MEDIA & TELECOMMUNICATIONS FUND
--------------------------------------------------------------------------------

    DIRECTORS
    Herbert Barg
    Alfred J. Bianchetti
    Martin Brody
    Dwight B. Crane
    Burt N. Dorsett
    Elliot S. Jaffe
    Stephen E. Kaufman
    Joseph J. McCann
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.
    James J. Crisona, Emeritus

    OFFICERS
    Heath B. McLendon
    President and Chief Executive Officer

    Lewis E. Daidone
    Senior Vice President and Treasurer

    Irving P. David
    Controller

    Christina T. Sydor
    Secretary

    INVESTMENT MANAGER
    SSBCiti Fund Management LLC

    INVESTMENT SUBADVISER
    Citibank, N.A.

    DISTRIBUTORS
    Salomon Smith Barney Inc.
    PFS Distributors Inc.

    CUSTODIAN
    State Street Bank & Trust Co.

    TRANSFER AGENT
    Citi Fiduciary Trust Company
    125 Broad Street, 11th Floor
    New York, New York 10004

    SUB-TRANSFER AGENT
    PFPCGlobal Fund Services
    P.O. Box 9699
    Providence, Rhode Island
    02940-9699

<PAGE>

--------------------------------------------------------------------------------
SMITH BARNEY GLOBAL MEDIA & TELECOMMUNICATIONS FUND
--------------------------------------------------------------------------------

This report is submitted for general information of the shareholders of Smith
Barney Sector Series Inc. -- Smith Barney Global Media & Telecommunications
Fund, but it may also be used as sales literature when preceded or accompanied
by the current Prospectus, which gives details about charges, expenses,
investment objectives and operating policies of the Fund. If used as sales
material after January 31, 2001, this report must be accompanied by performance
information for the most recently completed calendar quarter.


SMITH BARNEY GLOBAL MEDIA &
   TELECOMMUNICATIONS FUND
Smith Barney Mutual Funds
388 Greenwich Street, MF-2
New York, New York 10013



For complete information on any Smith Barney Mutual Funds, including management
fees and expenses, call or write your financial professional for a free
prospectus. Read it carefully before you invest or send money.



www.smithbarney.com/mutualfunds



SALOMON SMITH BARNEY [LOGO]


Salomon Smith Barney is a service mark of Salomon Smith Barney Inc.

FD02131  12/00


<PAGE>



--------------------------------------------------------------------------------
                                  SMITH BARNEY
                               SECTOR SERIES INC.

                             GLOBAL TECHNOLOGY FUND
--------------------------------------------------------------------------------

               RESEARCH SERIES | ANNUAL REPORT | OCTOBER 31, 2000


[LOGO OMITTED] SMITH BARNEY MUTUAL FUNDS
               YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)


--------------------------------------------------------------------------------
             NOT FDIC INSURED o NOT BANK GUARANTEED o MAY LOSE VALUE
--------------------------------------------------------------------------------


<PAGE>

[LOGO] Research Series

Annual Report o October 31, 2000

SMITH BARNEY GLOBAL
TECHNOLOGY FUND

CITIBANK GLOBAL ASSET MANAGEMENT

Citibank, N.A., through its Citibank Global Asset Management division, is the
subadviser to the Fund. Composed of a seasoned group of investment and research
professionals, the Fund's management team follows a systematic and rigorous
approach designed to provide appropriate exposure to each market sector.

FUND OBJECTIVE

The Fund seeks long-term capital appreciation. The Fund normally invests at
least 80% of its assets in securities of companies principally engaged in, but
not limited to, offering, using or developing products, processes or services
that will provide or will benefit significantly from technological advances and
improvements.

FUND FACTS

FUND INCEPTION
------------------------------------------
August 31, 2000

           CLASS A   CLASS B   CLASS L
------------------------------------------
NASDAQ      STFAX       --      SBGTX
INCEPTION  8/31/00   8/31/00   8/31/00
------------------------------------------


SMITH BARNEY GLOBAL TECHNOLOGY FUND*
TOTAL RETURNS OCTOBER 31, 2000

                           WITHOUT SALES CHARGES(1)

                        Class A     Class B    Class L
------------------------------------------------------------
Since Inception         (22.98)%    (23.07)%   (23.07)%
(August 31, 2000)**
------------------------------------------------------------


                          WITH SALES CHARGES(2)

                        Class A     Class B    Class L
------------------------------------------------------------
Since Inception         (26.83)%    (26.92)%   (24.60)%
(August 31, 2000)**
------------------------------------------------------------


*   Since the Fund focuses its investments on companies  involved in technology,
    an  investment  in the fund may  involve  a  greater  degree of risk than an
    investment in other mutual funds with greater diversification.

**  Not Annualized

(1) Assumes  reinvestment  of all dividends and capital gain  distributions,  if
    any,  at net asset value and does not reflect  deduction  of the  applicable
    sales  charges  with  respect  to  Class A and L  shares  or the  applicable
    contingent  deferred  sales  charges  ("CDSC") with respect to Class B and L
    shares.

(2) Assumes  reinvestment  of all dividends and capital gain  distributions,  if
    any,  at net asset  value.  In  addition,  Class A and L shares  reflect the
    deduction  of  the  maximum  initial  sales  charges  of  5.00%  and  1.00%,
    respectively;  Class B shares  reflect the deduction of a 5.00% CDSC,  which
    applies if shares are  redeemed  within  one year from  purchase.  This CDSC
    declines by 1.00% the first year after  purchase and thereafter by 1.00% per
    year until no CDSC occurs  after 5 years.  Class L shares  also  reflect the
    deduction of 1.00% CDSC,  which  applies if shares are  redeemed  within the
    first year of purchase.



<PAGE>

--------------------------------------------------------------------------------
WHAT'S INSIDE

Your Investment in the Smith Barney
Global Technology Fund ..............................  1
Letter from the Chairman ............................  2
Fund at a Glance ....................................  3
Shareholder Letter ..................................  4
Schedule of Investments .............................  8
Statement of Assets and Liabilities ................. 10
Statement of Operations ............................. 11
Statement of Changes in Net Assets .................. 12
Notes to Financial Statements ....................... 13
Financial Highlights ................................ 17
Independent Auditors' Report ........................ 20

[LOGO OMITTED] SMITH BARNEY MUTUAL FUNDS
               YOUR SERIOUS MONEY. PROFESSIONALLY MANAGED.(SM)

--------------------------------------------------------------------------------
  Investment Products: Not FDIC Insured o Not Bank Guaranteed o May Lose Value
--------------------------------------------------------------------------------


<PAGE>

--------------------------------------------------------------------------------
           Your Investment in the SMITH BARNEY GLOBAL TECHNOLOGY FUND
--------------------------------------------------------------------------------

EXPOSURE TO GROWTH OPPORTUNITIES

Led by Citibank Global Asset Management ("CGAM"), the Fund seeks long-term
capital appreciation through exposure to the global technology industry.

[GRAPHIC OMITTED]
     INNOVATION THAT TRANSFORMS THE WORLD
     Technological innovation has changed the face of the world. As further
     advancements continue to be made in many different areas across the globe,
     it may be beneficial to maintain broad exposure to global technology
     companies. CGAM continually monitors the global changes taking place, and
     looks to offer investors access to companies on the leading edge of
     technology.

[GRAPHIC OMITTED]
     DIVERSIFICATION IN A TARGETED SECTOR*
     An investment in the Fund offers investors a way to invest in a broad range
     of companies in the technology sectors, both in the U.S. and abroad. The
     Fund's investments may include companies in a wide range of industries,
     such as computers, semi-conductors, software, electronics and
     communications.

[GRAPHIC OMITTED]
     THE BENEFITS OF EXHAUSTIVE FUNDAMENTAL SECURITIES ANALYSIS--
     THE RESEARCH SERIES
     The Research Series is a selection of Smith Barney Mutual Funds built on a
     foundation of substantial buy-side research under the direction of CGAM.
     This series of funds focus on potential opportunities from well-defined
     industries, sectors and trends.

[GRAPHIC OMITTED]
     A COMMITMENT TO MANAGING YOUR SERIOUS MONEY
     SSB Citi Asset Management Group ("SSB Citi"), the investment management
     division of Citigroup, comprises Smith Barney Asset Management, Salomon
     Brothers Asset Management and Citibank Global Asset Management, each an
     organization with extensive investment capabilities.

     SSB Citi, as a member of one of the largest financial services providers in
     the world, offers you the benefits of our unparalleled global capabilities.

     At SSB Citi, you gain access to portfolio management delivered
     professionally. We are proud to offer you, the serious investor, a variety
     of managed solutions.

*Please note that because the Fund invests in a single  industry,  its shares do
 not represent a complete  investment  program,  and the value of its shares may
 fluctuate more than shares invested in a broader range of industries.

   1 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

--------------------------------------------------------------------------------
                            LETTER FROM THE CHAIRMAN
--------------------------------------------------------------------------------

The new  millennium,  so far, has been marked by higher  volatility and concerns
that the bull  market in stocks may be running  out of steam.  At SSB Citi Asset
Management Group ("SSB Citi"),  we have instituted many positive  changes,  with
the ultimate  goal of offering our  investors a  well-rounded  menu of stock and
bond funds that can be tailored to a wide range of investment objectives.

We believe that your serious money demands professional management.  Since 1937,
Smith Barney has managed the serious money of  individuals,  their  families and
their businesses. Today, with over $398.6 billion in assets under management,(1)
SSB Citi offers  choices and  solutions,  uniting the  distinguished  history of
Smith Barney with the unparalleled global reach of its parent, Citigroup.

A FEW THOUGHTS ON SECTOR INVESTING

Over the past few years,  we have seen how profoundly the  advancements  made in
sectors such as technology and  telecommunications  have  transformed  our daily
lives.  Computer  applications,  wireless  communications  and  biotechnological
discoveries  have created new investment  opportunities.  The new and developing
sectors of the economy that are involved in bringing  these  products,  services
and  technologies  to life may  offer  exceptional  growth  potential,  and many
investors  should  consider having a portion of their  investment  portfolios in
them.

Although most of us recognize that certain sectors drive the economy, we believe
it is much more  difficult to  determine  which  global  technologies  companies
within a particular  sector will perform  better than the others over time.  The
team of experienced professionals at Citibank N.A. thoroughly researches a broad
range of companies within a given sector and carefully analyzes them, looking to
identify those companies that they believe offer the greatest  growth  potential
over the long term. Through this exhaustive and proprietary process,  CGAM seeks
to offer you an opportunity  for you to  participate in those  companies that it
believes are best-positioned in their respective industries.

[PHOTO OMITTED]
HEATH B. MCLENDON
CHAIRMAN
-----------------

Yet, when  investing in a sector fund, it is important to understand  that these
funds may experience a significant amount of short-term volatility. We think you
need to maintain a long-term  investment  horizon and remember that sector funds
may be  appropriate as part of an overall  portfolio that has more  conservative
investments.

When you  invest  with SSB  Citi,  you can do so with the  confidence  that your
interests come first, your investment success is paramount and that the ultimate
in resources is being committed to your financial success.

Thank you for your confidence in our investment management approach.

Sincerely,


/s/ Heath B. McLendon
---------------------

Heath B. McLendon
Chairman

NOVEMBER 6, 2000




---------------
(1) AS OF OCTOBER 31, 2000. THIS FIGURE REPRESENTS RETAIL, INSTITUTIONAL, MONEY
    AND SEPARATE ACCOUNTS.


   2 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders



<PAGE>

--------------------------------------------------------------------------------
 SMITH BARNEY GLOBAL TECHNOLOGY FUND AT A GLANCE
--------------------------------------------------------------------------------

GROWTH OF $10,000 INVESTED IN THE
SMITH BARNEY GLOBAL TECHNOLOGY FUND VS. MSCI ALL-WORLD INDEX & MSCI INFORMATION
TECHNOLOGY INDEX
--------------------------------------------------------------------------------
        AUGUST 31, 2000 (COMMENCEMENT OF OPERATIONS) -- OCTOBER 31, 2000

[THE TABLE BELOW REPRESENTS LINE CHART IN PRINTED PIECE]

              SMITH BARNEY GLOBAL      MSCI ALL-WORLD      MSCI INFORMATION
            TECHNOLOGY FUND CLASS A       INDEX+          TECHNOLOGY INDEX++

8/31/00               9500                  10000               10000
9/30/00               7750                   9469                8146
10/31/00              7316                   9312                7521

A $10,000  investment in the Fund made on August 31, 2000 would have declined to
$7,317 with sales charge (as of October 31, 2000).  The graph shows how the Fund
compares to its  benchmark for the same period.  The graph  includes the initial
sales charge on the Fund (no comparable charge exists for the index) and assumes
all dividends and distributions are reinvested at Net Asset Value.

+  The Morgan Stanley Capital  International  All-World  Index ("MSCI  All-World
   Index")  represents  the  performance of 47 markets in both the developed and
   the emerging markets in Africa,  Asia,  Australia,  Europe, North America and
   South  America.  Please note than an investor  cannot  invest  directly in an
   index.

++ The Morgan Stanley Capital International  Information Technology Index ("MSCI
   Information  Technology  Index") is comprised of assets from MSCI's developed
   and  emerging  markets  universes  and includes  assets from the  information
   technology sector as defined by Morgan Stanley Dean Witter's "Global Industry
   Classification Standard." The index is composed of the developed and emerging
   markets  countries  in the MSCI World  Extended  and EMF  Indices.  The index
   constituents  are weighted  according to their market  capitalizations.  Each
   country's  weight  within the index will  fluctuate  over time  according  to
   market  movements.  The index is calculated  without dividends and with gross
   dividends  reinvested and is calculated in U.S.  dollars and local  currency.
   Past  performance  is not indicative of future  results.  Please note than an
   investor cannot invest directly in an index.

-----------------------------------------------------------
               TOP TEN COMMON STOCK HOLDINGS*
-----------------------------------------------------------

 1. MICROSOFT CORP. .................................  9.7%

 2. CISCO SYSTEMS INC. ..............................  8.7

 3. INTEL CORP. .....................................  6.8

 4. NOKIA OYJ .......................................  5.3

 5. EMCCORP. ........................................  4.9

 6. INTERNATIONAL BUSINESS MACHINES CORP. ...........  4.4

 7. ORACLE CORP. ....................................  3.9

 8. NORTEL NETWORKS CORP. ...........................  3.3

 9. AMERICA ONLINE INC. .............................  2.8

10. MOTOROLA INC. ...................................  2.5

-----------------------------------------------------------
                   PORTFOLIO BREAKDOWN*
-----------------------------------------------------------

[THE TABLE BELOW REPRESENTS PIE CHART IN PRINTED PIECE]

 0.6% Netherlands
 3.3% Canada
 1.1% United Kingdom
 1.9% Germany
 2.4% Short-Term
 2.8% Sweden
 3.7% France
 5.3% Finland
 9.8% Japan
69.1% United States

* As a percentage of total investments.

   3 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

DEAR SHAREHOLDER:

We are  pleased to provide  the  inaugural  annual  report for the Smith  Barney
Sector Series  Inc.--Smith Barney Global Technology Fund ("Fund") for the period
from August 31, 2000 through October 31, 2000. In this report we have summarized
the  period's  prevailing  economic  and market  conditions,  and  outlined  our
investment  strategy.  The  information  provided in this letter  represents the
opinion of the manager and is not intended to be a forecast of future events,  a
guarantee of future results nor investment advice.

Further,  there is no assurance that certain securities will remain in or out of
the Fund.  Please refer to pages 8 through 9 for a complete list and  percentage
breakdown of the Fund's holdings.  A detailed summary of the Fund's  performance
can be found in the  appropriate  sections  that  follow.  We hope you find this
report to be useful and informative.

PERFORMANCE UPDATE

Since its  inception  on August 31, 2000 through  October 31,  2000,  the Fund's
Class A shares,  without and with sales charges,  generated  negative returns of
22.98% and 26.83%,  respectively.  In  comparison,  the Morgan  Stanley  Capital
International  All-World Index  ("MSCIAll-World  Index")(1)  returned a negative
6.88% and the Morgan Stanley Capital International  Information Technology Index
("MSCIInformation  Technology Index")(2) returned a negative 24.79% for the same
period. Please note that past performance is not indicative of future results.

GLOBAL SECTOR EQUITY INVESTING--THE CGAM PROCESS

Our approach to global sector investing is based on exhaustive  research that is
intensely focused and led by a group of seasoned  investment  professionals with
extensive  industry  expertise.  We  look  for  analytical  consistency  through
intensive modeling and strict application of a consistent valuation methodology.

The Fund's management team is made up of a high-quality, seasoned investment and
research professionals who follow a systematic and rigorous strategy designed to
provide the right exposure to various  industries  within any particular  sector
they  cover.  Our  exhaustive  fundamental  research  evaluates  a  universe  of
businesses  in its  global  quest to  identify  and  participate  in  attractive
investment opportunities.

                        A THREE-STEP RESEARCH PROCESS

              -------------     --------------     ------------------
               FUNDAMENTAL       QUANTITATIVE       ACTIVE PORTFOLIO
                RESEARCH           RESEARCH            MANAGEMENT
              -------------     --------------     ------------------

We apply a proprietary,  systematic,  risk-conscious  approach to investing.  We
combine  fundamental  research,   quantitative  research  and  active  portfolio
management  to create  portfolios  that they think should  generate  competitive
returns while helping to moderate risk over time.

In our view, there can be no substitute for in-depth  analysis,  which can often
provide a significant  competitive edge in understanding  company  fundamentals.
(Of course,  no  assurances  can be made that our approach  will  ultimately  be
successful.)


--------------
(1) THE MSCI ALL-WORLD  INDEX  REPRESENTS THE PERFORMANCE OF MARKETS IN BOTH THE
    DEVELOPED AND THE EMERGING MARKETS IN AFRICA, ASIA, AUSTRALIA, EUROPE, NORTH
    AMERICA  AND SOUTH  AMERICA.  PLEASE  NOTE THAT AN  INVESTOR  CANNOT  INVEST
    DIRECTLY IN AN INDEX.

(2) THE MSCI  INFORMATION  TECHNOLOGY  INDEX IS  COMPRISED OF ASSETS FROM MSCI'S
    DEVELOPED  AND  EMERGING  MARKETS  UNIVERSES  AND  INCLUDES  ASSETS FROM THE
    INFORMATION  TECHNOLOGY  SECTOR AS DEFINED BY MORGAN  STANLEY DEAN  WITTER'S
    "GLOBAL  INDUSTRY  CLASSIFICATION  STANDARD."  THE INDEX IS  COMPOSED OF THE
    DEVELOPED AND EMERGING MARKETS  COUNTRIES IN THE MSCIWORLD  EXTENDED AND EMF
    INDICES.  THE INDEX  CONSTITUENTS  ARE  WEIGHTED  ACCORDING  TO THEIR MARKET
    CAPITALIZATIONS.  EACH COUNTRY'S WEIGHT WITHIN THE INDEX WILL FLUCTUATE OVER
    TIME  ACCORDING  TO  MARKET  MOVEMENTS.  THE  INDEX  IS  CALCULATED  WITHOUT
    DIVIDENDS  AND WITH GROSS  DIVIDENDS  REINVESTED  AND IS  CALCULATED IN U.S.
    DOLLARS  AND LOCAL  CURRENCY.  PLEASE NOTE THAT AN  INVESTOR  CANNOT  INVEST
    DIRECTLY IN AN INDEX.

    MANAGEMENT BELIEVES THAT THE PERFORMANCE COMPARISON TO THE SPECIFIC INDEX IS
    A MORE  APPROPRIATE  COMPARISON THAN A COMPARISON TO ANY SINGLE  BROAD-BASED
    SECURITIES  MARKET  INDEX,  SUCH AS THE MSCI  ALL-WORLD  INDEX,  BECAUSE THE
    SPECIFIC  INDEX HAS BEEN  TAILORED TO THE FUND'S  INVESTMENT  OBJECTIVE.  IN
    ADDITION TO THIS SECTOR-SPECIFIC COMPARISON, HOWEVER, THE FUND WILL CONTINUE
    TO COMPARE ITS  PERFORMANCE  AGAINST MORE  BROADLY-BASED  SECURITIES  MARKET
    INDEXES WHICH ARE REQUIRED TO BE INCLUDED IN THIS REPORT.  PAST  PERFORMANCE
    IS NOT  INDICATIVE OF FUTURE  RESULTS.  PLEASE NOTE THAT AN INVESTOR  CANNOT
    INVEST DIRECTLY IN AN INDEX.

   4 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

Our  fundamental,  proprietary  research looks to add value to active  portfolio
management by providing timely and unbiased information to their decision-making
processes.  Our team conducts on-site company visits and exhaustive  research to
uncover the companies that they think have:

o Superior products or services
o Outstanding managements
o Solid balance sheets
o Market leadership
o Leading innovation

In our opinion,  these are the companies'  strengths that can potentially create
real value and lead to strong earnings and sales growth, which ultimately drives
stock prices.

--------------------------------------------------------------------------------
                    ACCORDING TO A REPORT BY THE WORLD TRADE
                      ORGANIZATION: "THE PROLIFERATION OF
                      ELECTRONIC COMMERCE IS PREDICTED TO
                   LOWER TRANSACTION COSTS, FACILITATE ENTRY
                  AND INCREASE COMPETITION. THIS, IN TURN, MAY
                   LOWER PRICES, INCREASE QUALITY AND CREATE
                     NEW AND MORE DIVERSE PRODUCTS, THEREBY
                    INCREASING ECONOMIC GROWTH AND WELFARE."

             SOURCE: "ELECTRONIC COMMERCE AND THE ROLE OF THE WTO,"
                         1998 WORLD TRADE ORGANIZATION.
--------------------------------------------------------------------------------

THE CGAM RESEARCH PROCESS DEFINED

We look to  differentiate  ourself from the  traditional  approach to investment
management  in a  number  of ways  that we think  we can add  value to  clients'
portfolios.  Our  management  style can best be  described as  disciplined,  yet
flexible.  Our formidable  global reach and local expertise enable us to nurture
research  teams with direct access to the regions and  industries  where they do
business.  Our  research  organization  is centered on a team  approach to stock
research and  selection by covering  hundreds of companies  and working  closely
together both within and across industry teams in a seamless  fashion to reach a
prudent consensus.

Each stock analyst builds intensive,  detailed company models from the ground up
that anticipate a particular company's financial  performance.  These models are
based on the company's  competitive  position  within the  industry,  quality of
product offerings,  costs and risks. These intensive models detail the analyst's
assumptions  for  potential  profitability  for the  company  going  forward and
provides some of the necessary  information to forecast company fundamentals and
make stock  recommendations.  The research team looks to ensure  consistency  in
industry  and  accounting  assumptions  and that in turn can  allow  for  better
comparisons of earnings forecasts.



   5 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

A common  valuation  framework--based  on the Dividend  Discount  Model  ("DDM")
allows for estimation of returns to fair value.  Simply stated, the DDM compares
a company's future discounted dividend stream to its current stock price.

We  believe  this  is a  valuable  and  consistent  method  to  provide  current
valuations to securities. The DDM-based valuation process, in our view, provides
a common  yardstick  that helps  analysts  and  portfolio  managers  compare the
relative  valuation of one company's  stock to another.  The equity analyst then
combines  the DDM  valuation  with other  fundamental  factors  such as earnings
surprises to come up with an investment rating on a company's stock.

THE SMITH BARNEY GLOBAL TECHNOLOGY FUND

Unlike many "thematic"  technology  research  efforts,  our technology team uses
both "top-down" and "bottom-up"  strategies to identify promising companies they
believe may offer long-term growth potential.

Our "top-down" assessment involves looking closely at the major trends,  current
events, high-level growth drivers and the structural assessment of profitability
impacting the technology  industry.  This assessment  also involves  examining a
company's  competitive position by determining what drives demand and management
capability.

--------------------------------------------------------------------------------
                   OUR SECTOR FUND MANAGEMENT STYLE CAN BEST
                   BE DESCRIBED AS DISCIPLINED, YET FLEXIBLE.
--------------------------------------------------------------------------------

The team's  "bottom-up"  assessment  relies on looking at individual  companies'
participation in the marketplace, their market share projections, cost structure
and investment  requirements,  in addition to growth  estimates and treatment of
market share tradeoffs.  To ensure internal  consistency in assessing technology
companies,  our team has developed an integrated  view of technology  consistent
across regions and within sub-sectors of the technology industry.

GLOBAL TECHNOLOGY SECTOR UPDATE

The global  technology  sector was characterized by higher volatility during the
period,  as investors began to reassess the valuations  placed on many companies
in the sector that had yet to post earnings.  However, despite this reassessment
by many investors during the beginning of the period, technology stocks began to
make up some of the  losses  they  had  experienced  in April  and in May.  Yet,
technology  remains to be  characterized  by record  volatility,  as the slowing
growth of the U.S. economy began to have a negative impact on earnings growth.

However,  we believe the reasons for owning technology stocks over the long term
remain  compelling.  We think that the technological  revolution is still in its
infancy and we remain  confident  that advances may continue to impact the world
in many  positive  ways,  especially  in  higher  productivity.  In  particular,
technology demand for enterprise servers and storage remains extremely robust.

Industry leaders such as Sun Microsystems,  EMC, and Network Appliances continue
to see  accelerating  demand for their products as global  corporations  further
embrace the Internet. All three companies have recently delivered earnings ahead
of expectations and have caused analysts to revise their forecasts higher.

We have built the Fund's  portfolio by carefully  following our  analysts'  best
global ideas within the hardware, software,  electronic equipment,  Internet and
information services industries,  while at the same time looking to control risk
in the  portfolio.  We strive for the highest  return  possible above the sector
return,  taking  into  account  the  risks  associated  with each  industry  and
sub-sector within the sector.

   6 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

Our positions  favor the  infrastructure  providers and  established  players --
hardware and software -- rather than the current "themes" in the sector. To help
control  risk,  we  apply   bottom-up  stock  selection  to  each  industry  and
sub-sector,  ensuring that we are capturing our analyst's best ideas within each
area.  Small  deviations  reflect our relative  opinions of one industry  versus
another within the sector, but are managed to control portfolio risk that arises
from industry volatility.

--------------------------------------------------------------------------------
                    THE MANAGEMENT OF THE FUND IS DRIVEN BY
                       ANALYST RECOMMENDATIONS, LONG-TERM
                     EARNINGS AND EARNINGS MOMENTUM FACTORS
                     THAT FORM THE BASIS OF EXPECTED FUTURE
                     RETURNS WITHIN THE TECHNOLOGY SECTOR.
--------------------------------------------------------------------------------

The Fund is presently  slightly  overweight in hardware companies  International
Business Machines Corp.  ("IBM") and Canon, and storage  component  manufacturer
EMC  Corporation  relative to the  benchmark.  The Fund is also  underweight  in
equipment  manufacturers,  although we see  opportunities  in Cisco  Systems and
Nortel  Networks,  two  equipment   manufacturers  whose  products  provide  the
"backbone" for Internet traffic.

Relative  to  the  benchmark,  we are  slightly  overweight  in the  information
services and  software  sectors,  and  underweight  in equipment  manufacturers.
Though underweight in equipment, we do like cellular phone provider Nokia. Nokia
has  been  gaining  share  at  the  expense  of  Ericsson,   and  though  almost
fairly-priced,  we feel its  strong  momentum  in a sector  where many names are
showing negative momentum will keep the stock strong.

We  identify  technology  companies  we are  currently  holding  in  the  Fund's
portfolio through our bottom-up  fundamental  research and stock selection,  yet
the overall  industry mix is  consistent  with the top-down  strategic  industry
themes,  which we use for estimate  forecasting  and rating  formulation.  Since
industries  within  this  sector  are  quick to  innovate  and  consolidate,  we
carefully  monitor the Fund's  holdings to reflect any changes  that may have an
impact on performance.

EXPERIENCED SECTOR FUND PORTFOLIO MANAGEMENT

The  management  of the  sector  funds is  driven  by  analyst  recommendations,
long-term  earnings  and  earnings  momentum,  which form the basis of  expected
future returns within any given sector.  These  expected  returns,  coupled with
detailed risk forecasts,  determine what holdings will be selected.  In building
and maintaining the Fund's portfolio,  we look to avoid a high risk-to-return on
their investments, and carefully monitor sector performance,  constantly looking
for any material changes and/or developments.

Thank you for  investing in the Smith Barney  Sector  Series  Inc.-Smith  Barney
Global  Technology  Fund.  We look forward to helping you pursue your  financial
goals in the years ahead.

Sincerely,

The Investment Team at
Citibank N.A.

NOVEMBER 6, 2000

   7 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

--------------------------------------------------------------------------------
 SCHEDULE OF INVESTMENTS                                       OCTOBER 31, 2000
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
     SHARES                            SECURITY                                                 VALUE
==============================================================================================================
<S>                 <C>                                                                             <C>
COMMON STOCK -- 97.6%

CANADA -- 3.3%
          3,694     Nortel Networks Corp. (Telecommunications)                                      $167,796
--------------------------------------------------------------------------------------------------------------

FINLAND -- 5.3%
          6,573     Nokia Oyj (Telecommunications)                                                   270,470
--------------------------------------------------------------------------------------------------------------

FRANCE -- 3.7%
          1,503     Alcatel (Telecommunications)                                                      91,705
            338     Cap Gemini (IT Consulting & Services)                                             53,923
            233     Sagem SA (Telecommunications)                                                     42,708
--------------------------------------------------------------------------------------------------------------
                                                                                                     188,336
--------------------------------------------------------------------------------------------------------------

GERMANY -- 1.9%
            484     SAP AG (Computer Software)                                                        97,551
--------------------------------------------------------------------------------------------------------------

JAPAN -- 9.8%
            200     Advantest (Semiconductor Equipment & Products)                                    26,083
          2,000     Canon Inc. (Office Electronics)                                                   79,366
          2,000     Fujitsu Group (Computers & Peripherals)                                           35,632
            400     Fujitsu Support and Services Inc. (Computers & Peripherals)                       48,609
          4,000     Hitachi (Electronic Equipment & Instruments)                                      42,891
            300     Kyocera Corp. (Electronic Equipment & Instruments)                                39,041
            300     Murata Manufacturing Co., Ltd. (Semiconductor Equipment & Products)               35,907
          2,000     NEC Corp. (Computers & Peripherals)                                               38,125
            300     Rohm Co.* (Semiconductor Equipment & Products)                                    75,636
            400     SoftBank Corp. (Internet Software & Services)                                     24,011
            300     Tokyo Electronics Ltd. (Semiconductor Equipment & Products)                       23,480
          4,000     Toshiba Corp. (Computers & Peripherals)                                           28,594
--------------------------------------------------------------------------------------------------------------
                                                                                                     497,375
--------------------------------------------------------------------------------------------------------------

NETHERLANDS -- 0.6%
          1,192     ASM Lithography Holdings * (Semiconductor Equipment & Products)                   32,581
--------------------------------------------------------------------------------------------------------------

SWEDEN -- 2.8%
         10,521     Ericsson Telecommunications (Telecommunications)                                 140,037
--------------------------------------------------------------------------------------------------------------

UNITED KINGDOM -- 1.1%
          4,396     Marconi Plc (Telecommunication)                                                   55,492
--------------------------------------------------------------------------------------------------------------

UNITED STATES -- 69.1%
          2,820     America Online Inc.* (Internet Software & Services)                              142,213
          1,569     Applied Materials Inc.* (Electronic Product Equipment)                            83,353
          2,761     Avaya Inc.* (Telecommunication)                                                   37,101
            272     Broadcom Corp.* (Semiconductor Equipment & Products)                              60,486
          8,177     Cisco Systems Inc.* (Computer Softwares)                                         440,536
          1,144     Corning Inc. (Telecommunications)                                                 87,516
          3,219     Dell Computer Corp.* (Electronic Data Processing Services)                        94,961
          2,811     EMC Corp.* (Computers & Peripherals)                                             250,355
          1,352     Electronics Data Systems Corp. (Electronic Data Processing Service)               63,460
          2,161     First Data Corp. (Electronic Data Processing Services)                           108,320
          1,191     General Motors Corp.* (Automobile)                                                38,588
          2,418     Hewlett Packard Co. (Computers & Peripherals)                                    112,286
          7,705     Intel Corp. (Semiconductor Equipment & Products)                                 346,725
          2,256     International Business Machines Corp. (Computers & Peripherals)                  222,216

</TABLE>



                       SEE NOTES TO FINANCIAL STATEMENTS.

    8 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 SCHEDULE OF INVESTMENTS                                       OCTOBER 31, 2000
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
     SHARES                            SECURITY                                                 VALUE
==============================================================================================================
<S>                 <C>                                                                          <C>
UNITED STATES (CONT'D)

          1,273     JDS Uniphase Corp.* (Electronic Products)                                    $   103,590
          4,039     Lucent Technologies Inc. (Telecommunications)                                     94,159
            999     Microchip Technology Inc.* (Semiconductor Equipment & Products)                   31,593
            905     Micron Technology Inc.* (Semiconductor Equipment & Products)                      31,449
          7,180     Microsoft Corp.*(Computer Softwares)                                             494,523
          5,062     Motorola Inc. (Telecommunications)                                               126,234
          6,070     Oracle Corp.* (Computer Softwares)                                               200,310
          1,401     Peoplesoft Inc.* (Computer Software)                                              61,140
          1,014     Qualcomm Inc.* (Telecommunications)                                               66,021
            894     Solectron Corp.* (Electronic Equipment & Instruments)                             39,336
          1,004     Symbol Technologies Inc. (Electrical Equipment)                                   45,619
          1,879     Texas Instruments Inc. (Semiconductor Equipment & Products)                       92,188
            775     Yahoo! Inc.* (Internet Software & Services)                                       45,434
--------------------------------------------------------------------------------------------------------------
                                                                                                   3,519,712
--------------------------------------------------------------------------------------------------------------

                    TOTAL COMMON STOCK
                    (Identified Cost -- $6,211,422)                                                4,969,350
==============================================================================================================

      FACE
     AMOUNT                            SECURITY                                                 VALUE
==============================================================================================================

DISCOUNT NOTE -- 2.4%

       $122,000     Student Loan Marketing Discount Note
                    6.45% due 11/01/00
                    (Identified Cost -- $122,000)                                                    122,000
==============================================================================================================

                    TOTAL INVESTMENTS -- 100%
                    (Identified Cost -- $6,333,422**)                                             $5,091,350
==============================================================================================================
</TABLE>

 * NON-INCOME PRODUCING SECURITY.
** AGGREGATE COST FOR FEDERAL INCOME TAX PURPOSES IS SUBSTANTIALLY THE SAME.

                       SEE NOTES TO FINANCIAL STATEMENTS.

   9 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders



<PAGE>

--------------------------------------------------------------------------------
 STATEMENT OF ASSETS AND LIABILITIES                           OCTOBER 31, 2000
--------------------------------------------------------------------------------
<TABLE>
<CAPTION>
ASSETS:
     <S>                                                                        <C>
     Investments, at value (Cost--$6,333,422)                                   $5,091,350
     Foreign currency, at value (Cost--$28,308)                                     28,086
     Cash                                                                              212
     Receivable for Fund shares sold                                                65,412
     Receivable for open forward foreign currency contract (Note 4)                     43
     Receivable for securities sold                                                 13,395
     Dividends and interest receivables                                                886
     Receivable from the Administrator (Note 10)                                    66,776
--------------------------------------------------------------------------------------------
     TOTAL ASSETS                                                                5,266,160
--------------------------------------------------------------------------------------------

LIABILITIES:
     Payable for Fund shares purchased                                             106,241
     Payable for securities purchased                                                2,284
     Distribution fees payable                                                       3,401
     Accrued expenses and other liabilities                                         61,088
--------------------------------------------------------------------------------------------
     TOTAL LIABILITIES                                                             173,014
--------------------------------------------------------------------------------------------
TOTAL NET ASSETS                                                                $5,093,146
============================================================================================

NET ASSETS:
     Par value of capital shares                                                       581
     Capital paid in excess of par value                                         6,402,550
     Undistributed net investment income                                            21,242
     Accumulated net realized loss
        from security transactions and foreign currencies                          (88,867)
     Net unrealized depreciation
        of investments and foreign currencies                                   (1,242,360)
--------------------------------------------------------------------------------------------
TOTAL NET ASSETS                                                                $5,093,146
============================================================================================

SHARES OUTSTANDING:
     Class A                                                                       137,418
     ---------------------------------------------------------------------------------------
     Class B                                                                       171,423
     ---------------------------------------------------------------------------------------
     Class L                                                                       271,774
     ---------------------------------------------------------------------------------------

NET ASSET VALUE:
     Class A (and redemption price)                                                  $8.78
     ---------------------------------------------------------------------------------------
     Class B *                                                                       $8.77
     ---------------------------------------------------------------------------------------
     Class L **                                                                      $8.77
     ---------------------------------------------------------------------------------------

MAXIMUM PUBLIC OFFERING PRICE PER SHARE:
     Class A (net asset value plus 5.26% of net asset value per share)               $9.24
     ---------------------------------------------------------------------------------------
     Class L (net asset value plus 1.01% of net asset value per share)               $8.86
============================================================================================
</TABLE>

 * REDEMPTION  PRICE IS NAV OF CLASS B SHARES  REDUCED BY A 5.00% CDSC IF SHARES
   ARE REDEEMED LESS THAN ONE YEAR FROM PURCHASE (SEE NOTE 2).

** REDEMPTION  PRICE IS NAV OF CLASS L SHARES  REDUCED BY A 1.00% CDSC IF SHARES
   ARE REDEEMED WITHIN THE FIRST YEAR OF PURCHASE.

                       SEE NOTES TO FINANCIAL STATEMENTS.

   10 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 STATEMENT OF OPERATIONS
--------------------------------------------------------------------------------

FOR THE PERIOD AUGUST 31, 2000  (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000

<TABLE>
<CAPTION>
INVESTMENT INCOME:
     <S>                                                                          <C>
     Interest                                                                     $ 10,132
     Dividends                                                                       1,220
     Less: Foreign withholding tax                                                    (116)
--------------------------------------------------------------------------------------------
     TOTAL INVESTMENT INCOME                                                        11,236
--------------------------------------------------------------------------------------------

EXPENSES:
     Management fees(Note 2)                                                         8,085
     Distribution fees (Note 2)                                                      6,660
     Shareholder communications                                                     30,509
     Custody fees                                                                   20,748
     Audit fees                                                                     17,667
     Legal fees                                                                      3,068
     Directors' fees                                                                 2,957
     Registration fees                                                               1,502
     Other                                                                           1,314
--------------------------------------------------------------------------------------------
     TOTAL EXPENSES                                                                 92,510
     Less: Aggregate amount waived by the Manager (Note 2)                          (8,085)
     Less: Expenses assumed by the administrator (Note 10)                         (66,776)
--------------------------------------------------------------------------------------------
     NET EXPENSES                                                                   17,649
--------------------------------------------------------------------------------------------
NET INVESTMENT LOSS                                                                 (6,413)
--------------------------------------------------------------------------------------------

REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS (NOTE 3):
     Realized Loss From:
        Security (excluding short-term securities)
           and foreign currency transactions                                       (67,872)
--------------------------------------------------------------------------------------------
     NET REALIZED LOSS                                                             (67,872)
--------------------------------------------------------------------------------------------
     INCREASE IN NET UNREALIZED DEPRECIATION                                    (1,242,360)
--------------------------------------------------------------------------------------------
NET LOSS ON INVESTMENTS                                                         (1,310,232)
--------------------------------------------------------------------------------------------
DECREASE IN NET ASSETS FROM OPERATIONS                                         $(1,316,645)
============================================================================================
</TABLE>





                       SEE NOTES TO FINANCIAL STATEMENTS.

   11 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders



<PAGE>

--------------------------------------------------------------------------------
 STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------

FOR THE PERIOD AUGUST 31, 2000  (COMMENCEMENT OF OPERATIONS) TO OCTOBER 31, 2000

<TABLE>
<CAPTION>
OPERATIONS:
     <S>                                                                       <C>
     Net investment loss                                                       $    (6,413)
     Net realized loss                                                             (67,872)
     Increase in net unrealized depreciation                                    (1,242,360)
--------------------------------------------------------------------------------------------
     DECREASE IN NET ASSETS FROM OPERATIONS                                     (1,316,645)
--------------------------------------------------------------------------------------------

FUND SHARE TRANSACTIONS (NOTE 9):
     Net proceeds from sale of shares                                            8,937,999
     Net asset value of shares issued for reinvestment of dividends                     --
     Cost of shares reacquired                                                  (2,528,208)
--------------------------------------------------------------------------------------------
     INCREASE IN NET ASSETS FROM FUND SHARE TRANSACTIONS                         6,409,791
--------------------------------------------------------------------------------------------

INCREASE IN NET ASSETS                                                           5,093,146

NET ASSETS:
     Beginning of period                                                                --
--------------------------------------------------------------------------------------------
     END OF PERIOD*                                                             $5,093,146
============================================================================================
* Includes undistributed net investment income:                                    $21,242
============================================================================================
</TABLE>

                       SEE NOTES TO FINANCIAL STATEMENTS.

   12 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1.  Significant Accounting Policies

The Smith Barney Global Technology Fund is a non-diversified  investment fund of
the Smith Barney Sector Series Inc. (the "Company"), a Maryland corporation. The
Company is registered  under the Investment  Company of 1940, as amended,  as an
open-end management  investment company and consists of this Fund and five other
separate  investment funds:  Smith Barney Financial  Services Fund, Smith Barney
Health  Sciences  Fund,  Smith  Barney  Technology  Fund,  Smith  Barney  Global
Biotechnology Fund and Smith Barney Global Media &  Telecommunications  Fund. On
August 31, 2000, the Fund commenced operations.

The  significant  accounting  policies  followed by the Fund are:  (a)  security
transactions are accounted for on trade date; (b) securities  traded in national
securities  markets are valued at the closing prices in the primary  exchange on
which they are traded;  securities listed or traded on certain foreign exchanges
or other  markets  whose  operations  are  similar to the U.S.  over-the-counter
market  (including  securities  listed on exchanges  where the primary market is
believed  to be  over-the-counter)  and the  securities  for  which  no sale was
reported  on that date are valued at the mean  between  the bid and ask  prices.
Securities  which are listed or traded on more than one  exchange  or market are
valued at the quotations on the exchange or market  determined to be the primary
market for such securities;  (c) securities for which market  quotations are not
available  will be valued  in good  faith at fair  market  value by or under the
direction of the Board of Directors;  (d) securities maturing within 60 days are
valued  at cost  plus  accreted  discount,  or minus  amortized  premium,  which
approximates  value;  (e) the  accounting  records of the Fund are maintained in
U.S. dollars.  All assets and liabilities  denominated in foreign currencies are
translated  into U.S.  dollars based on the rate of exchange of such  currencies
against  U.S.  dollars  on  the  date  of  valuation.  Purchases  and  sales  of
securities,  and income and  expenses  are  translated  at the rate of  exchange
quoted on the respective date that such  transactions are recorded.  Differences
between  income or expense  amounts  recorded and collected or paid are adjusted
when reported by the custodian;  (f) interest income,  adjusted for amortization
or premium and  accretion  of  discount,  is recorded on an accrual  basis;  (g)
dividend  income is recorded on the  ex-dividend  date;  foreign  dividends  are
recorded  on the  ex-dividend  date or as  soon  as  practical  after  the  Fund
determines the existence of a dividend  declaration after exercising  reasonable
due diligence;  (h) dividends and  distributions to shareholders are recorded on
the  ex-dividend  date;  (i)  gains  or  losses  on the sale of  securities  are
calculated by using the specific  identification method; (j) direct expenses are
charged to each class; management fees and general expenses are allocated on the
basis of  relative  net  assets;  (k) the  character  of income  and gains to be
distributed are determined in accordance with income tax regulations,  which may
differ from generally accepted  accounting  principles;  (l) the Fund intends to
comply with the  requirements of the Internal  Revenue Code of 1986, as amended,
pertaining  to  regulated  investment  companies  and to make  distributions  of
taxable income  sufficient to relieve it from  substantially  all Federal income
and excise taxes;  (m) the character of income and gains to be  distributed  are
determined  in  accordance  with  income tax  regulations  which may differ from
generally accepted accounting principles. At October 31, 2000, reclassifications
were  made  to  the  Fund's  capital  accounts  to  reflect  permanent  book/tax
differences  and income and gains available for  distributions  under income tax
regulations.  Accordingly,  the Fund  reclassified  $6,660 from paid in capital,
$21,168 from  accumulated  net realized  loss and $27,828 to  undistributed  net
investment income. Net investment income, net realized gains and net assets were
not affected by this change;  and (n) estimates and  assumptions are required to
be made regarding  assets,  liabilities and changes in net assets resulting from
operations  when  financial   statements  are  prepared.   Changes  in  economic
environment,  financial  markets and any other  parameters  used in  determining
these estimates could cause actual results to differ.

In  addition,  the Fund may enter into  forward  exchange  contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market  rate as an  unrealized  gain or  loss.  Realized  gains  or  losses  are
recognized when contracts are settled.

   13 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

2.  Management Agreement and
    Other Transactions

SSB Citi Fund  Management  LLC  ("SSBC"),  a subsidiary  of Salomon Smith Barney
Holdings  Inc.  ("SSBH"),  which,  in turn,  is a subsidiary  of Citigroup  Inc.
("Citigroup"),  acts as investment  manager to the Fund.  The  management fee is
computed at an annual rate of 0.95% of the  average  daily net assets.  SSBC has
delegated  the  daily  management  of  the  Portfolio  to  Citibank  N.A.,  (the
"SubAdviser"),  an affiliate of SSBC.  For  services  provided to the Fund,  the
manager  pays the  Subadviser  a  subadvisory  fee computed at an annual rate of
0.65% of the Fund's average daily net assets.  The management fees paid amounted
to $8,085, of which all was waived for the period ended October 31, 2000.

Salomon  Smith Barney Inc.  acts as the Fund  distributor.  Salomon Smith Barney
Inc.   ("SSB"),   another   subsidiary   of  SSBH,  as  well  as  certain  other
broker-dealers,  continues  to sell Fund shares to the public as a member of the
selling group.

Citi Fiduciary Trust Company ("CFTC"),  another subsidiary of Citigroup, acts as
the Fund's  transfer  agent and  PFPCGlobal  Fund Services  ("PFPC") acts as the
Fund's  sub-transfer  agent.  CFTCreceives  fees and asset-based  fees that vary
according  to the account  size and type of  account.  PFPC is  responsible  for
shareholder  recordkeeping and financial processing for all shareholder accounts
and is paid by CFTC.  For the  period  ended  October  31,  2000,  the Fund paid
transfer agent fees of $453 to CFTC.

There is a maximum  initial  sales  charge of 5.00% and 1.00% for Class A shares
and L shares, respectively. There is a contingent deferred sales charge ("CDSC")
of 5.00% on Class B shares,  which applies if redemption  occurs within one year
from initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred.  Class L shares also have a 1.00% CDSC,  which  applies if  redemption
occurs within the first year of purchase.

For the period  ended  October  31,  2000,  CDSCs paid to SSB and sales  charges
received by SSB were approximately:

                             CLASS A       CLASS B      CLASS L
================================================================================
CDSCs                        $ --          $ --         $ --
--------------------------------------------------------------------------------
Sales Charges                $48,000       $ --         $30,000
================================================================================

Pursuant to a  Distribution  Plan,  the Fund pays a service fee with  respect to
Class A, B and L shares  calculated  at an annual  rate of 0.25% of the  average
daily net assets of each respective class. The Fund also pays a distribution fee
with  respect to Class B and L shares  calculated  at an annual rate of 0.75% of
the average daily net assets for each class, respectively.

For the period ended  October 31, 2000,  total  Distribution  Plan fees incurred
were:

                             CLASS A       CLASS B      CLASS L
================================================================================
Distribution Plan Fees        $617         $2,363       $3,680
================================================================================

All officers and one Director of the Fund are employees of SSB.


3.  Investments

During the period ended October 31, 2000,  the  aggregate  cost of purchases and
proceeds  from  sales  of  investments  (including  maturities,   but  excluding
short-term securities) were as follows:

================================================================================
Purchases                                           $ 6,520,665
--------------------------------------------------------------------------------
Sales                                               $   244,576
================================================================================

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

================================================================================
Gross unrealized appreciation                       $    61,858
Gross unrealized depreciation                        (1,304,152)
--------------------------------------------------------------------------------
Net unrealized depreciation                         $(1,242,294)
================================================================================




<PAGE>

4.  Forward Foreign Currency Contracts

At October 31, 2000,  the Fund had open forward  foreign  currency  contracts as
described  below.  The Fund bears the market risk that  arises  from  changes in
foreign currency exchange rates. The unrealized loss on the contracts  reflected
in the accompanying financial statements were as follows:


   14 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders



<PAGE>

--------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

                          LOCAL       MARKET     SETTLEMENT    UNREALIZED
FOREIGN CURRENCY        CURRENCY       VALUE        DATE          LOSS
================================================================================
TO BUY
Euro                     18,179       15,428       11/2/00         $43
--------------------------------------------------------------------------------
Net Unrealized Loss
  on Forward Foreign
  Currency Contracts                                               $43
================================================================================


5.  Option Contracts

Premiums  paid when put or call  options  are  purchased  by the Fund  represent
investments,  which are marked-to-market daily. When a purchased option expires,
the Fund will  realize a loss in the amount of the premium  paid.  When the Fund
enters into a closing  sales  transaction,  the Fund will realize a gain or loss
depending on whether the proceeds from the closing sales transaction are greater
or less than the  premium  paid for the  option.  When the Fund  exercises a put
option, it will realize a gain or loss from the sale of the underlying  security
and the  proceeds  from such sale will be decreased by the amount of the premium
originally paid. When the Fund exercises a call option, the cost of the security
that  the  Fund  purchases  upon  exercise  will  be  increased  by the  premium
originally paid.

At October 31, 2000, the Fund had no open purchased call or put options.

When a Fund writes a call or put option, an amount equal to the premium received
by the Fund is recorded as a liability,  the value of which is  marked-to-market
daily.  When a written option  expired,  the Fund realizes a gain. When the Fund
enters into a closing  purchase  transaction,  the Fund  realizes a gain or loss
depending  upon whether the cost of the closing  transaction  is greater or less
than the premium originally  received,  without regard to any unrealized gain or
loss on the  underlying  security,  and the liability  related to such option is
eliminated.  When a written  call option is  exercised  the cost of the security
sold will be decreased by the premium  originally  received.  When a written put
option is exercised,  the amount of the premium originally  received will reduce
the cost of the security which the Fund  purchased  upon exercise.  When written
index options are exercised, settlement is made in cash.

The risk associated with purchasing options is limited to the premium originally
paid. The Fund enters into options for hedging  purposes.  The risk in writing a
call  option is that the Fund gives up the  opportunity  to  participate  in any
increase in the price of the underlying  security beyond the exercise  price.The
risk in  writing a put option is that the Fund is exposed to the risk of loss if
the market price of the underlying security declines.

At October 31, 2000, the Fund did not write any options.


6.  Futures Contracts

Initial  margin  deposits  made upon  entering  into futures are  recognized  as
assets. Securities equal to the initial margin amount are segregated in the name
of the  broker.  Additional  securities  are also  segregated  up to the current
market value of the futures contract.  During the period the futures contract is
open,  changes in the value of the contracts are recognized as unrealized  gains
or losses by "marking-to-market" on a daily basis to reflect the market value of
the contract at the end of each day's  trading.  Variation  margin  payments are
received or made and recognized as assets due from or liabilities due to broker,
depending  upon  whether  unrealized  gains or  losses  are  incurred.  When the
contract  is  closed,  the Fund  records a  realized  gain or loss  equal to the
differences between the proceeds from (or cost of) the closing  transactions and
the Fund's basis in the contract.

The Fund enters into such  contracts  to hedge a portion of its  portfolio.  The
Fund  bears  the  market  risk  that  arises  from  changes  in the value of the
financial instruments and securities indices (futures contracts).

At October 31, 2000, the Fund had no open futures contracts.


7.  Repurchase Agreements

The Fund  purchases  (and its custodian  takes  possession  of) U.S.  government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon


   15 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

higher repurchase price. The Fund requires  continual  maintenance of the market
value of the collateral (plus accrued interest) in amounts at least equal to the
repurchase price.


8.  Concentration of Risk

The Fund  normally  invests  at least 80% of its  assets in  technology  related
investments.  As a result of this concentration  policy,  which is a fundamental
policy of the Fund,  the Fund's  investment  may be subject to greater  risk and
market fluctuation than a fund that invests in securities representing a broader
range of investment alternatives.

The Fund's  investments  in foreign  securities may involve risks not present in
domestic investments.  Since securities may be denominated in a foreign currency
and may require  settlement in foreign  currencies and pay interest or dividends
in foreign  currencies,  changes in the relationship of these foreign currencies
to the U.S. dollar can  significantly  affect the value of these investments and
earnings of the Fund.  Foreign  investments may also subject the Fund to foreign
government exchange  restrictions,  expropriation,  taxation or other political,
social or economic  developments,  all of which could  affect the market  and/or
credit risk of the investments.


9.  Capital Shares

At October 31, 2000, the Fund had 750 million shares of capital stock authorized
with a par value of $0.001 per share. The Fund has the ability to issue multiple
classes of shares. Each share of a class represents an identical interest in the
Fund and has the same  rights,  except  that each class bears  certain  expenses
specifically related to the distribution of its shares.

At October 31, 2000,  total paid-in  capital  amounted to the following for each
class:

                             CLASS A       CLASS B      CLASS L
================================================================================
Total Paid-in Capital      $1,582,454    $1,871,687   $2,955,650
================================================================================


10.  Assumption of Expenses

SSBC has voluntarily agreed to pay a portion of the expenses of the Fund for the
period ended October 31, 2000, which amounted to $66,776 to maintain a voluntary
expense  limitation  of 0.80%  for a Class A  average  daily  net  assets.  This
voluntary expense limitation may be discontinued at any time.

Transactions in shares of each class were as follows:

                                                     AUGUST 31, 2000
                                               (COMMENCEMENT OF OPERATIONS)
                                                    TO OCTOBER 31, 2000
                                             --------------------------------
                                               SHARES                AMOUNT
================================================================================
CLASS A
Shares sold                                   357,900              $4,023,235
Shares issued on reinvestment                      --                      --
Shares reacquired                            (220,482)             (2,440,781)
--------------------------------------------------------------------------------
Net Increase                                  137,418              $1,582,454
================================================================================
CLASS B
Shares sold                                   174,643              $1,902,738
Shares issued on reinvestment                      --                      --
Shares reacquired                              (3,220)                (31,051)
--------------------------------------------------------------------------------
Net Increase                                  171,423              $1,871,687
================================================================================
CLASS L
Shares sold                                   278,101              $3,012,026
Shares issued on reinvestment                      --                      --
Shares reacquired                              (6,327)                (56,376)
--------------------------------------------------------------------------------
Net Increase                                  271,774              $2,955,650
================================================================================

   16 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS A SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                            $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                           (0.11)
   Net realized and unrealized loss                              (2.51)
--------------------------------------------------------------------------------
Total Loss From Operations                                       (2.62)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                            --
   Net realized gain                                                --
--------------------------------------------------------------------------------
Total Distributions                                                 --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                 $  8.78
--------------------------------------------------------------------------------
TOTAL RETURN                                                    (22.98)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                               $1,206
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                       1.56%+
   Net investment income                                          0.39%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                              5%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

       Net investment loss per share                            $(0.11)
       RATIOS:
       Expenses to average net assets                            10.36%+
       Net investment loss to average net assets                 (8.41)%+
================================================================================

NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE SHARES DURING
      THE PERIOD.

+  ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.


   17 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

--------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS B SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                            $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                           (0.16)
   Net realized and unrealized loss                              (2.47)
--------------------------------------------------------------------------------
Total Loss From Operations                                       (2.63)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                            --
   Net realized gain                                                --
--------------------------------------------------------------------------------
Total Distributions                                                 --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                 $  8.77
--------------------------------------------------------------------------------
TOTAL RETURN                                                    (23.07)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                               $1,503
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                       2.29%+
   Net investment loss                                           (1.15)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                              5%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                             $(0.16)
      RATIOS:
      Expenses to average net assets                             11.08%+
      Net investment loss to average net assets                  (9.95)%+
================================================================================

NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE OF SHARES DURING
      THE PERIOD.

+  ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.


   18 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 FINANCIAL HIGHLIGHTS (CONTINUED)
--------------------------------------------------------------------------------

FOR A SHARE OF EACH CLASS OF CAPITAL STOCK FROM AUGUST 31, 2000 (COMMENCEMENT OF
OPERATIONS) TO OCTOBER 31, 2000

CLASS L SHARES
================================================================================
NET ASSET VALUE, BEGINNING OF PERIOD                            $11.40
--------------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS:
   Net investment loss                                           (0.16)
   Net realized and unrealized loss                              (2.47)
--------------------------------------------------------------------------------
Total Loss From Operations                                       (2.63)
--------------------------------------------------------------------------------
LESS DISTRIBUTIONS FROM:
   Net investment income                                            --
   Net realized gain                                                --
--------------------------------------------------------------------------------
Total Distributions                                                 --
--------------------------------------------------------------------------------
NET ASSET VALUE, END OF PERIOD                                 $  8.77
--------------------------------------------------------------------------------
TOTAL RETURN                                                    (23.07)%++
--------------------------------------------------------------------------------
NET ASSETS, END OF PERIOD (000'S)                               $2,383
--------------------------------------------------------------------------------
RATIOS TO AVERAGE NET ASSETS:
   Expenses                                                       2.28%+
   Net investment loss                                           (1.23)%+
--------------------------------------------------------------------------------
PORTFOLIO TURNOVER RATE                                              5%
================================================================================

NOTE: IF AGENTS OF THE FUND HAD NOT VOLUNTARILY WAIVED A PORTION OF THEIR FEES,
      THE NET INVESTMENT LOSS PER SHARE AND THE RATIOS WOULD HAVE BEEN AS
      FOLLOWS:

      Net investment loss per share                             $(0.16)
      RATIOS:
      Expenses to average net assets                             11.08%+
      Net investment loss to average net assets                 (10.03)%+
================================================================================

NOTE: THE PER SHARE AMOUNTS WERE COMPUTED USING MONTHLY AVERAGE OF SHARES DURING
      THE PERIOD.

+ ANNUALIZED.

++ TOTAL RETURN IS NOT ANNUALIZED, AS IT MAY NOT BE REPRESENTATIVE OF THE TOTAL
   RETURN FOR THE YEAR.

                       SEE NOTES TO FINANCIAL STATEMENTS.


   19 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders

<PAGE>

--------------------------------------------------------------------------------
 INDEPENDENT AUDITORS' REPORT
--------------------------------------------------------------------------------

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF THE SMITH BARNEY SECTOR SERIES INC.:

We have audited the accompanying statement of assets and liabilities,  including
the schedule of  investments,  of Smith Barney Global  Technology  Fund of Smith
Barney  Sector  Series Inc. as of October 31, 2000,  the related  statements  of
operations, the statements of changes in net assets and financial highlights for
the period August 31, 2000  (Commencement  of  Operations)  through  October 31,
2000.  These  financial   highlights  are  the   responsibility  of  the  Fund's
management.  Our  responsibility  is to express  an  opinion on these  financial
statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements and financial highlights are free of material misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by  correspondence  with the custodian.
As to  securities  purchased  or sold  but not yet  received  or  delivered,  we
performed  other  appropriate  auditing  procedures.   An  audit  also  includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above present fairly, in all material respects,  the financial position of Smith
Barney Global  Technology Fund of Smith Barney Sector Series Inc., as of October
31,  2000,  the  results of its  operations,  the  changes in its net assets and
financial highlights for the period August 31, 2000 through October 31, 2000, in
conformity with accounting principles generally accepted in the United States of
America.

/s/ KPMG LLP
------------

New York, New York
December 11, 2000

   20 SMITH BARNEY GLOBAL TECHNOLOGY FUND | 2000 Annual Report to Shareholders


<PAGE>

SMITH BARNEY
GLOBAL TECHNOLOGY FUND

    DIRECTORS                                   INVESTMENT MANAGER
    Herbert Barg                                SSB Citi Fund Management LLC
    Alfred J. Bianchetti
    Martin Brody                                INVESTMENT SUBADVISER
    Dwight B. Crane                             Citibank, N.A.
    Burt N. Dorsett
    Elliot S. Jaffe                             DISTRIBUTORS
    Stephen E. Kaufman                          Salomon Smith Barney Inc.
    Joseph J. McCann                            PFS Distributors Inc.
    Heath B. McLendon, Chairman
    Cornelius C. Rose, Jr.                      CUSTODIAN
    James J. Crisona, Emeritus                  State Street Bank & Trust Co.

                                                TRANSFER AGENT
    OFFICERS                                    Citi Fiduciary Trust Company
    Heath B. McLendon                           125 Broad Street, 11th Floor
    President and Chief Executive Officer       New York, New York 10004

    Lewis E. Daidone                            SUB-TRANSFER AGENT
    Senior Vice President and Treasurer         PFPC Global Fund Services
                                                P.O. Box 9699
    Irving P. David                             Providence, Rhode Island
    Controller                                  02940-9699

    Christina T. Sydor
    Secretary

<PAGE>

SMITH BARNEY GLOBAL TECHNOLOGY FUND
================================================================================

This report is submitted for general  information of the  shareholders  of Smith
Barney  Sector Series Inc. -- Smith Barney Global  Technology  Fund,  but it may
also be used as sales  literature  when preceded or  accompanied  by the current
Prospectus,  which gives details about charges, expenses,  investment objectives
and operating  policies of the Fund. If used as sales material after January 31,
2001,  this report must be accompanied by performance  information  for the most
recently completed calendar quarter.

SMITH BARNEY  GLOBAL  TECHNOLOGY  FUND
Smith Barney Mutual Funds
388 Greenwich Street, MF-2
New York, New York 10013



For complete information on any Smith Barney Mutual Funds,  including management
fees  and  expenses,  call  or  write  your  financial  professional  for a free
prospectus. Read it carefully before you invest or send money.

WWW.SMITHBARNEY.COM/MUTUALFUNDS



   [SALOMON SMITH BARNEY LOGO]

Salomon Smith Barney is a service mark of Salomon Smith Barney Inc.


FD02130 12/00

<PAGE>


      -------------------------------------------------------------------
                                 SMITH BARNEY
                              SECTOR SERIES INC.
                            NATURAL RESOURCES FUND
      -------------------------------------------------------------------

        RESEARCH SERIES    |    ANNUAL REPORT    |    OCTOBER 31, 2000





                       [LOGO] Smith Barney Mutual Funds

                Your Serious Money. Professionally Managed.(SM)


            -------------------------------------------------------
             NOT FDIC INSURED . NOT BANK GUARANTEED . MAY LOSE VALUE
            -------------------------------------------------------
<PAGE>

Smith Barney
Natural Resources Fund

The Smith Barney Natural Resources Fund ("Portfolio") seeks long-term capital
appreciation by investing primarily in equity and debt securities of U.S. and
foreign issuers in natural resources industries.


Smith Barney Natural Resources Fund
Average Annual Total Returns
October 31, 2000

                                    Without Sales Charges/(1)/
                      ----------------------------------------------------------
                        Class A          Class B             Class L
================================================================================
One-Year                 2.02%            1.32%               1.43%
--------------------------------------------------------------------------------
Five-Year                3.57             2.94                3.01
--------------------------------------------------------------------------------
Ten-Year                 3.80             N/A                 N/A
--------------------------------------------------------------------------------
Since Inception+         2.37             4.29               (1.59)
================================================================================

                                        With Sales Charges/(2)/
                      ----------------------------------------------------------
                        Class A          Class B             Class L
================================================================================
One-Year                (3.07)%          (3.68)%             (0.56)%
--------------------------------------------------------------------------------
Five-Year                2.51             2.77                2.81
--------------------------------------------------------------------------------
Ten-Year                 3.27             N/A                 N/A
--------------------------------------------------------------------------------
Since Inception+         1.99             4.29               (1.76)
================================================================================

(1)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value and does not reflect the deduction of the
     applicable sales charges with respect to Class A and L shares or the
     applicable contingent deferred sales charges ("CDSC") with respect to Class
     B and L shares.

(2)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value. In addition, Class A and L shares reflect the
     deduction of the maximum initial sales charges of 5.00% and 1.00%,
     respectively; Class B shares reflect the deduction of a 5.00% CDSC, which
     applies if shares are redeemed within one year from purchase. Thereafter,
     the CDSC declines by 1.00% per year until no CDSC is incurred. Class L
     shares also reflect the deduction of a 1.00% CDSC, which applies if shares
     are redeemed within the first year of purchase.

     All figures represent past performance and are not a guarantee of future
     results. Investment returns and principal value will fluctuate, and
     redemption value may be more or less than the original cost.

 +   Inception dates for Class A, B and L shares are November 24, 1986, November
     6, 1992 and November 7, 1994, respectively.

FUND HIGHLIGHT

On Tuesday, December 5, 2000, the shareholders of Smith Barney Sector Series
Inc. -- Smith Barney Natural Resources Fund approved a reorganization of the
Portfolio into Smith Barney Fundamental Value Fund, Inc., whose portfolio
manager is also John Goode. The merger is currently scheduled to occur on
Friday, December 8, 2000.

NASDAQ SYMBOL

           Class A                      SPMMX
           Class B                      SPMBX
           Class L                      SPMLX

WHAT'S INSIDE

Shareholder Letter..................................................  1

Historical Performance..............................................  4

Smith Barney Natural Resources Fund at a Glance.....................  6

Schedule of Investments.............................................  7

Statement of Assets and Liabilities.................................  9

Statement of Operations............................................. 10

Statements of Changes in Net Assets................................. 11

Notes to Financial Statements....................................... 12

Financial Highlights................................................ 17

Independent Auditors' Report........................................ 20
<PAGE>

Shareholder Letter

[PHOTO]                 [PHOTO]

Heath B.                John G.
McLendon                Goode

Chairman                Vice President and
                        Investment Officer


Dear Shareholder:

We are pleased to provide the annual report for the Smith Barney Sector Series
Inc. -- Smith Barney Natural Resources Fund ("Portfolio") for the year ended
October 31, 2000. In this report we have summarized the period's prevailing
economic and market conditions and outlined the Portfolio's investment strategy.
We hope you find this report useful and informative.

Special Shareholder Notice

On Tuesday, December 5, 2000, the shareholders of Smith Barney Sector Series
Inc. -- Smith Barney Natural Resources Fund approved a reorganization of the
Portfolio into Smith Barney Fundamental Value Fund, Inc. ("Fundamental Value
Fund") whose portfolio manager is also John Goode. The merger is currently
scheduled to occur on Friday, December 8, 2000.

There are several reasons for taking this direction. Originally, the Portfolio
was focused primarily on gold stocks and then its charter was broadened to
include natural resources companies in general. Even though this expanded the
range of investment alternatives, the Portfolio's focus continued to be rather
narrow. As such, it performed well when natural resources stocks were performing
well and the Portfolio underperformed when they were out-of-favor.

The Fundamental Value Fund has a broader investment charter. Its primary
investing philosophy is to "buy leading franchises at depressed prices for
reasons thought to be temporary." In other words, price plays a key role in
making new investment decisions. And while no guarantees can be given, we
believe this approach benefits from the highly volatile nature, in recent years,
of the sectors making up a leading index such as the Standard & Poor's 500 Index
("S&P 500")./1/ As an example, earlier this year technology stocks reached
exceedingly high valuations and major sales were made in the January through
February period in the Fundamental Value Fund. These assets were re-deployed
into depressed health care, financial, and energy stocks, which have
subsequently performed well. These decisions, based in part on the extraordinary
volatility between market segments, contributed to the solid relative
performance of the Fundamental Value Fund year-to-date. At this time, the
Fundamental Value Fund has outperformed the S&P 500 by 22%. (Please note past
performance is not indicative of future results.)

The Fundamental Value Fund can and does invest in natural resources companies
when we believe them to be attractive. Most of these investments are carried in
the basic materials segment of the portfolio. Basic materials account for about
2% of the S&P 500 and the Fundamental Value Fund now holds about 9% of its
assets in natural resources (basic materials) companies, indicating we find
their values compelling at this time.

Smith Barney Sector Series Inc. -- Smith Barney Natural Resources Performance
Update

For the year ended October 31, 2000, the Portfolio's Class A shares, without and
with sales charges, returned 2.02% and a negative 3.07%, respectively. In
comparison, the Morgan Stanley Capital International World Index ("MSCI World
Index")/2/ returned 1.09% for the same period.


__________________
1   S&P 500 is a market capitalization-weighted measure of 500 widely held
    common stocks. Please note that an investor cannot invest directly in an
    index.

__________________
2   MSCI World Index is an unmanaged index of foreign stocks. Please note that
    an investor cannot invest directly in an index.

     1 Smith Barney Natural Resources Fund  | 2000 Annual Report to Shareholders
<PAGE>

Natural Resources-As Mark Twain Said, "The Rumors of Their Death Have Been
Greatly Exaggerated."

Given all the rhetoric about "New Economy"/3/ products and services, classic raw
materials have been consigned by many to a position reserved for buggy whips a
century ago. However, we still need to get around in automobiles that require
gasoline and we find ourselves dependent on heating and air conditioning to keep
warm in winter and cool in summer. Energy clearly has not gone out of style.

People continue to live in homes, many of which are even larger than those built
in recent decades. For all the talk of a paperless society, the desks around our
offices seem strangely littered with the "white stuff." Remarkably, eating has
not gone out of style and each day six billion plus people in the world need to
feed themselves!

It is true is that our economy is becoming less dependent on things such as
steel, copper, fertilizer, chemicals and oil but demand continues to grow. Some
natural resources, such as aluminum, are benefiting as they are substituted for
other heavier or most costly alternatives. The world, however, still is much
more dependent on natural resources than the U.S. Incremental increases in gross
domestic product ("GDP")/4/ require proportionately more natural resources
inputs than in this country.

The supply side is changing as well. Mergers and consolidations are reducing
capacity as facilities that are marginally economic are shutting down. Beginning
about five years ago, shareholders and consultants advised many producers of
natural resources that they were destroying shareholder wealth, more often
than not, when they built new facilities. As a result, many segments within
natural resources have seen limited increases in capacity in recent years.
Consolidation and limited capacity increases suggest to us that the business
cycle for many natural resources companies may be less severe in the future.
Prices should be stronger over the next cycle than in previous ones where there
were substantial capacity additions that created "boom-bust" conditions.

Economic "Tailwinds" May Be Close At Hand

We believe the U.S. dollar may peak shortly and that this may benefit many
natural resources. As of October 31, 2000, the Portfolio had 19% of its assets
in paper and forest products stocks. We believe these companies have been
adversely affected by the strong U.S. dollar even though their operating rates
have reached levels that historically would have suggested the return of pricing
power. Foreign competitors operating in weaker currency environments have had a
competitive advantage and have been able to limit U.S. companies' ability to
raise prices. We believe this is about to change.

Recently, for the first time in a number of years, we added a 7% position in
gold stocks. These too could benefit from a weaker dollar. However, we also
think the timing is good for a substantial move in this much maligned sector of
the market. Sentiment, as measured by market vane, is at historically low
bullish levels. In other words, expectations are exceedingly low. Stocks are
selling at five-year lows, which often are 70 to 80% below their peaks.

Recently there has been much discussion about weakness in the "Old Economy"/5/
area of the stock market. In our opinion, a considerable amount of this
weakness may be traceable to the remarkable strength of the U.S. dollar. A
somewhat weaker dollar could translate into much better price action for many
natural resource companies whose shares are very depressed at this time.

Oil & Natural Gas Prices - An Aberration or Harbinger of Things to Come?

Oil prices have risen substantially in the last few years. Moving from $12 a
barrel to about $35 a barrel recently. The Organization of the Petroleum
Exporting Countries ("OPEC") is viewed as having had much to do with this but
the fact is that world demand has recovered to the point that there is not a
large amount of spare capacity. The Portfolio has approximately 31% of its
assets invested in energy services and oil stocks.

___________________
3    The New Economy represents those companies in the technology,
     telecommunications and Internet sectors.

4    GDP is the market value of the goods and services produced by labor and
     property in the U.S. GDP is comprised of consumer and government purchases,
     private domestic investments and net exports of goods and services.

5    The Old Economy represents more established, "blue-chip" companies.

     2  Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

Natural gas for years was priced at $2/MCF (1,000 cubic feet) or less. Even with
3-D seismic and other technological innovations, new supplies did not keep pace
with demand and the country's reserve/production ratio deteriorated. At the same
time, demand for clean burning fuels increased. Natural gas prices may average
about $4/MCF this year and even more in 2001. A cold winter could push prices
above $5/MCF. Natural gas still is a commodity but it seems clear that prices
are likely to remain well above the 1989-1999 average price for the foreseeable
future.

We believe much tighter supply-demand conditions may be characteristic of many
segments within natural resources in the next few years. Price changes for
paper, lumber, aluminum, copper, nickel, steel, chemicals, and gold, to name a
few, may not be as extreme as those now occurring in natural gas, but the trend
should be higher over time.

In summary, a weaker dollar, somewhat higher annual inflation rates (3% to
4%), increasing demand, and limited capacity additions portend better times
ahead for natural resources companies. We also are encouraged that many of them
are utilizing excess cash flow to repurchase their shares.

In closing, thank you for your investment in the Smith Barney Sector Series
Inc. -- Smith Barney Natural Resources Fund.

Sincerely,



/s/ Heath B. McLendon              /s/ John G. Goode
-------------------------          --------------------------
Heath B. McLendon                  John G. Goode
Chairman                           Vice President and
                                   Investment Officer

November 21, 2000

The information provided in this letter represents the opinion of the manager
and is not intended to be a forecast of future events, a guarantee of future
results nor investment advice. Further, there is no assurance that certain
securities will remain in or out of the Portfolio. Please refer to pages 7 and 8
for a list and percentage breakdown of the Portfolio's holdings. Also, please
note any discussion of the Portfolio's holdings is as of October 31, 2000 and is
subject to change.

     3  Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

<TABLE>
<CAPTION>
===================================================================================================================================
   Historical Performance -- Class A Shares
===================================================================================================================================
                                          Net Asset Value
                                    -----------------------------
                           Beginning              End           Income          Capital Gain       Return        Total
   Year Ended               of Year             of Year       Dividends         Distributions    of Capital     Returns/(1)/
====================================================================================================================================
<S>                       <C>                   <C>           <C>               <C>               <C>           <C>
   10/31/00                   $    18.85         $   19.23       $   0.00          $   0.00          $  0.00           2.02%
------------------------------------------------------------------------------------------------------------------------------------
   10/31/99                        16.56             18.85           0.00              0.00             0.00          13.83
------------------------------------------------------------------------------------------------------------------------------------
   10/31/98                        23.23             16.56           0.00              0.16             0.00         (28.13)
------------------------------------------------------------------------------------------------------------------------------------
   10/31/97                        22.95             23.23           0.33              0.00             0.00           2.67
------------------------------------------------------------------------------------------------------------------------------------
   10/31/96                        16.50             22.95           0.00              0.00             0.00          39.09
------------------------------------------------------------------------------------------------------------------------------------
   10/31/95                        21.44             16.50           0.00              0.00             0.00         (23.04)
------------------------------------------------------------------------------------------------------------------------------------
   10/31/94                        18.89             21.44           0.00              0.00             0.00          13.50
------------------------------------------------------------------------------------------------------------------------------------
   10/31/93                        13.27             18.89           0.00              0.00             0.00          42.35
------------------------------------------------------------------------------------------------------------------------------------
   10/31/92                        13.93             13.27           0.06              0.00             0.03          (4.09)
------------------------------------------------------------------------------------------------------------------------------------
   10/31/91                        13.63             13.93           0.00              0.00             0.00           2.20
===================================================================================================================================
     Total                                                       $   0.39          $   0.16          $  0.03
====================================================================================================================================
</TABLE>


<TABLE>
<CAPTION>
====================================================================================================================================
   Historical Performance -- Class B Shares
====================================================================================================================================
                                         Net Asset Value
                                    ----------------------------
                                    Beginning         End          Income         Capital Gain        Return          Total
   Year Ended                        of Year        of Year       Dividends       Distributions     of Capital      Returns/(1)/
====================================================================================================================================
<S>                                 <C>             <C>           <C>             <C>               <C>             <C>
   10/31/00                           $    18.15     $   18.39    $      0.00      $       0.00        $    0.00          1.32%
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/99                                16.00         18.15           0.00              0.00             0.00         13.44
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/98                                22.60         16.00           0.00              0.16             0.00        (28.61)
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/97                                22.32         22.60           0.15              0.00             0.00          1.95
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/96                                16.15         22.32           0.00              0.00             0.00         38.20
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/95                                21.14         16.15           0.00              0.00             0.00        (23.60)
-----------------------------------------------------------------------------------------------------------------------------------
   10/31/94                                18.75         21.14           0.00              0.00             0.00         12.75
------------------------------------------------------------------------------------------------------------------------------------
   Inception*-- 10/31/93                   13.35         18.75           0.00              0.00             0.00         40.45+
====================================================================================================================================
     Total                                                        $      0.15      $       0.16        $    0.00
====================================================================================================================================
</TABLE>

     4  Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

<TABLE>
<CAPTION>
====================================================================================================================================
   Historical Performance -- Class L Shares
====================================================================================================================================
                               Net Asset Value
                            ----------------------
                            Beginning        End           Income         Capital Gain            Return              Total
   Year Ended                of Year       of Year        Dividends       Distributions          of Capital         Returns/(1)/
====================================================================================================================================
<S>                         <C>            <C>            <C>               <C>                    <C>            <C>
   10/31/00                 $   18.20      $    18.46      $   0.00         $     0.00             $   0.00                  1.43%
------------------------------------------------------------------------------------------------------------------------------------
   10/31/99                     16.03           18.20          0.00               0.00                 0.00                 13.54
------------------------------------------------------------------------------------------------------------------------------------
   10/31/98                     22.62           16.03          0.00               0.16                 0.00                (28.54)
------------------------------------------------------------------------------------------------------------------------------------
   10/31/97                     22.32           22.62          0.15               0.00                 0.00                  2.04
------------------------------------------------------------------------------------------------------------------------------------
   10/31/96                     16.16           22.32          0.00               0.00                 0.00                 38.12
------------------------------------------------------------------------------------------------------------------------------------
   Inception* -- 10/31/95       20.63           16.16          0.00               0.00                 0.00                (21.67)+
====================================================================================================================================
     Total                                                 $   0.15         $     0.16             $   0.00
====================================================================================================================================
</TABLE>

<TABLE>
<CAPTION>
====================================================================================================================================
   Average Annual Total Returns
====================================================================================================================================
                                                                             Without Sales Charges/(1)/
                                                                     --------------------------------------------
                                                                     Class A            Class B             Class L
====================================================================================================================================
<S>                                                                  <C>                <C>                 <C>
   Year Ended 10/31/00                                                2.02%              1.32%                1.43%
------------------------------------------------------------------------------------------------------------------------------------
   Five Years Ended 10/31/00                                          3.57               2.94                 3.01
------------------------------------------------------------------------------------------------------------------------------------
   Ten Years Ended 10/31/00                                           3.80                N/A                  N/A
------------------------------------------------------------------------------------------------------------------------------------
   Inception* through 10/31/00                                        2.37               4.29                (1.59)
====================================================================================================================================

<CAPTION>
                                                                                 With Sales Charges/(2)/
                                                                       -----------------------------------------------
                                                                       Class A            Class B             Class L
====================================================================================================================================
<S>                                                                    <C>               <C>                  <C>
   Year Ended 10/31/00                                                  (3.07)%           (3.68)%             (0.56)%
-----------------------------------------------------------------------------------------------------------------------------------
   Five Years Ended 10/31/00                                             2.51              2.77                2.81
------------------------------------------------------------------------------------------------------------------------------------
   Ten Years Ended 10/31/00                                              3.27               N/A                 N/A
------------------------------------------------------------------------------------------------------------------------------------
   Inception* through 10/31/00                                           1.99              4.29               (1.76)
====================================================================================================================================


</TABLE>

<TABLE>
<CAPTION>
====================================================================================================================================
   Cumulative Total Returns
====================================================================================================================================

                                                                                      Without Sales Charges/(1)/
====================================================================================================================================
<S>                                                                                   <C>
   Class A (10/31/90 through 10/31/00)                                                           38.61%
------------------------------------------------------------------------------------------------------------------------------------
   Class B (Inception* through 10/31/00)                                                         39.86
------------------------------------------------------------------------------------------------------------------------------------
   Class L (Inception* through 10/31/00)                                                         (9.15)
====================================================================================================================================
</TABLE>

(1)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value and does not reflect the deduction of the
     applicable sales charges with respect to Class A and L shares or the
     applicable contingent deferred sales charges ("CDSC") with respect to Class
     B and L shares.

(2)  Assumes reinvestment of all dividends and capital gain distributions, if
     any, at net asset value. In addition, Class A and L shares reflect the
     deduction of the maximum initial sales charges of 5.00% and 1.00%,
     respectively; Class B shares reflect the deduction of a 5.00% CDSC, which
     applies if shares are redeemed within one year from initial purchase and
     declines thereafter by 1.00% per year until no CDSC is incurred. Class L
     shares also reflect the deduction of a 1.00% CDSC, which applies if shares
     are redeemed within the first year of purchase.

 +   Total return is not annualized, as it may not be representative of the
     total return for the year.

 *   Inception dates for Class A, B and L shares are November 24, 1986, November
     6, 1992 and November 7, 1994, respectively.

     5  Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

================================================================================
Smith Barney Natural Resources Fund at a Glance (unaudited)
================================================================================

Growth of $10,000 Invested in Class A Shares of the Smith Barney Natural
Resources Fund vs. MSCI World Index and Standard & Poor's 500 Index+
--------------------------------------------------------------------------------


                                    [GRAPH]

                         Natural        MSCI       S&P
                        Resources      World       500
                        Fund Inc.      Index      Index

              10/90       9,498        10,000     10,000
              10/91       9,707        11,643     13,342
              10/92       9,310        11,099     14,669
              10/93      13,253        14,172     16,855
              10/94      15,042        15,329     17,507
              10/95      11,576        16,866     22,130
              10/96      16,101        19,706     27,461
              10/97      16,531        23,106     36,277
              10/98      11,880        26,730     44,261
              10/99      13,523        33,460     55,619
              10/00      13,796        34,009     58,998


+ Hypothetical illustration of $10,000 invested in Class A shares on October 31,
  1990, assuming deduction of the maximum 5.00% sales charge at the time of
  investment and the reinvestment of dividends and capital gains, if any, at
  net asset value through October 31, 2000. The Morgan Stanley Capital
  International World Index ("MSCI World Index") is an arithmetic average
  weighted by the market value performance of 1,468 securities listed on the
  stock exchanges of the USA, Europe, Canada, Australia, New Zealand and the Far
  East. The Standard & Poor's 500 Index is an index composed of widely held
  common stocks listed on the New York Stock Exchange, American Stock Exchange
  and the over-the-counter market. Figures for the index include the
  reinvestment of dividends. The Indexes are unmanaged and not subject to the
  same management and trading expenses as a mutual fund. An investor cannot
  invest directly in an index. The performance of the Portfolio's other classes
  may be greater or less than the Class A shares' performance indicated on this
  chart, depending on whether greater or lesser sales charges and fees were
  incurred by shareholders investing in the other classes.

  All figures represent past performance and are not a guarantee of future
  results. Investment returns and principal value will fluctuate, and redemption
  values may be more or less than the original cost. No adjustment has been made
  for shareholder tax liability on dividends or capital gains.

                             Exposure by Country*

     United States..............................................   93.3%

     United Kingdom.............................................    4.6

     Russia.....................................................    2.1


                        Top Ten Common Stock Holdings*

     Nucor Corp.................................................    5.2%

     Weyerhaeuser Co............................................    4.9

     Rio Tinto PLC..............................................    4.6

     Anadarko Petroleum Corp....................................    4.5

     Mead Corp..................................................    4.4

     Engelhard Corp.............................................    4.4

     Schlumberger Ltd...........................................    4.3

     Georgia-Pacific Group......................................    4.3

     Alcoa Inc..................................................    4.1

     Brush Engineered Materials Inc.............................    4.1

*    As a percentage of total investments. Please note these holdings are as of
     October 31, 2000 and are subject to change.

                             Portfolio Breakdown*

                                                      19.5% Paper Products
                                         2.0% Electronics  - Semiconductor

                                                                5.2% Steel

                                                            5.3% Machinery

                                                            2.1% Telephone

                                                             7.0% Aluminum

                                                              14.7% Metals

                                                            6.1% Chemicals

                                                              10.1% Energy
                                                       Service & Equipment

                                          21.1% Oil Exploration & Products

                                                                 6.9% Gold


6  Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

================================================================================
Schedule of Investments                                        October 31, 2000
================================================================================

<TABLE>
<CAPTION>
        SHARES                                                     SECURITY                                VALUE
====================================================================================================================
<S>                                                                <C>                                 <C>
COMMON STOCK -- 100.0%

Aluminum -- 7.0%
  50,700   Alcoa Inc.                                                                                  $  1,454,456
 196,000   Kaiser Aluminum Corp.*+                                                                          992,250
--------------------------------------------------------------------------------------------------------------------
                                                                                                          2,446,706
--------------------------------------------------------------------------------------------------------------------

Chemicals -- 6.1%
  50,000   Advanced Polymer Systems, Inc.*                                                                  159,375
  74,100   Engelhard Corp.                                                                                1,546,838
  15,000   Rohm & Haas Co.                                                                                  450,937
--------------------------------------------------------------------------------------------------------------------
                                                                                                          2,157,150
--------------------------------------------------------------------------------------------------------------------

Electronics- Semiconductor -- 2.0%
  71,000   MEMC Electronic Materials, Inc.*                                                                 705,563
--------------------------------------------------------------------------------------------------------------------

Energy Service & Equipment -- 10.1%
  40,000   Baker Hughes Inc.                                                                              1,375,000
  20,000   Schlumberger Ltd.                                                                              1,522,500
  39,200   Varco International, Inc.*                                                                       676,200
--------------------------------------------------------------------------------------------------------------------
                                                                                                          3,573,700
--------------------------------------------------------------------------------------------------------------------

Gold -- 6.9%
  40,000   AngloGold Ltd., Sponsored ADR                                                                    575,000
  40,000   Barrick Gold Corp.                                                                               535,000
  55,000   Newmont Mining Corp.                                                                             745,937
  70,000   Placer Dome Inc.                                                                                 568,750
--------------------------------------------------------------------------------------------------------------------
                                                                                                          2,424,687
--------------------------------------------------------------------------------------------------------------------

Machinery -- 5.3%
  20,000   Caterpillar Inc.                                                                                 701,250
  31,800   Deere & Co.                                                                                    1,170,638
--------------------------------------------------------------------------------------------------------------------
                                                                                                          1,871,888
--------------------------------------------------------------------------------------------------------------------

Metals -- 14.7%
  70,100   Brush Engineered Materials Inc.                                                                1,432,669
 110,000   Freeport-McMoRan Copper & Gold, Inc., Class B Shares*                                            873,125
 100,000   Rio Tinto PLC                                                                                  1,623,442
  86,000   RTI International Metals, Inc.*                                                                1,247,000
--------------------------------------------------------------------------------------------------------------------
                                                                                                          5,176,236
--------------------------------------------------------------------------------------------------------------------

Oil Exploration & Products -- 21.1%
  26,000   Abacan Resource Corp., Canada*                                                                        78
  25,000   Anadarko Petroleum Corp.                                                                       1,601,250
  25,000   Apache Corp.                                                                                   1,382,812
  37,900   Burlington Resources Inc.                                                                      1,364,400
  48,000   Conoco Inc., Class B Shares                                                                    1,305,000
  21,200   Texaco Inc.                                                                                    1,252,125
  20,000   USX-Marathon Group                                                                               543,750
--------------------------------------------------------------------------------------------------------------------
                                                                                                          7,449,415
--------------------------------------------------------------------------------------------------------------------
</TABLE>

                      See Notes to Financial Statements.

7    Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

================================================================================
Schedule of Investments (continued)                             October 31, 2000
================================================================================

<TABLE>
<CAPTION>

  SHARES                                                    SECURITY                                    VALUE
=====================================================================================================================
<S>                                                         <C>                                      <C>
Paper Products -- 19.5%
  55,900   Georgia-Pacific Group                                                                     $   1,502,313
  53,000   Mead Corp.                                                                                    1,533,688
 135,200   PT Inti Indorayon Utama Tbk, Sponsored ADR*                                                         135
  88,200   Smurfit-Stone Container Corp.*                                                                1,190,700
  90,000   Stora Enso Oyj, Sponsored ADR*                                                                  911,250
  36,900   Weyerhaeuser Co.                                                                              1,731,994
---------------------------------------------------------------------------------------------------------------------
                                                                                                         6,870,080
---------------------------------------------------------------------------------------------------------------------

Steel -- 5.2%
  52,600   Nucor Corp.                                                                                   1,824,573
---------------------------------------------------------------------------------------------------------------------

Telephone -- 2.1%
  84,000   Rostelecom, Sponsored ADR+                                                                      735,000
---------------------------------------------------------------------------------------------------------------------
           TOTAL INVESTMENTS -- 100%
           (Cost-- $30,963,082**)                                                                    $  35,234,998
=====================================================================================================================
</TABLE>

 * Non-income producing security.
 + All or a portion of this security is on loan (See Note 6).
** Aggregate cost for Federal income tax purposes is substantially the same.


                      See Notes to Financial Statements.

8     Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

<TABLE>
<CAPTION>
=========================================================================================================
  Statement of Assets and Liabilities                                                    October 31, 2000
=========================================================================================================
<S>                                                                                      <C>
ASSETS:
  Investments, at value (Cost--$30,963,082)                                               $  35,234,998
  Collateral for securities on loan (Note 6)                                                  1,723,200
  Cash                                                                                          144,583
  Dividends receivable                                                                           13,928
-------------------------------------------------------------------------------------------------------
  Total Assets                                                                               37,116,709
-------------------------------------------------------------------------------------------------------
LIABILITIES:
  Payable for securities on loan (Note 6)                                                     1,723,200
  Payable for Fund shares purchased                                                              33,643
  Management fees payable                                                                        11,936
  Distribution fees payable                                                                       9,649
  Accrued expenses                                                                               89,243
-------------------------------------------------------------------------------------------------------
  Total Liabilities                                                                           1,867,671
-------------------------------------------------------------------------------------------------------
Total Net Assets                                                                          $  35,249,038
=======================================================================================================
NET ASSETS:
  Par value of capital shares                                                             $       1,875
  Capital paid in excess of par value                                                        49,187,975
  Undistributed net investment income                                                             4,416
  Accumulated net realized loss from security transactions and foreign currencies           (18,217,144)
  Net unrealized appreciation of investments                                                  4,271,916
-------------------------------------------------------------------------------------------------------
Total Net Assets                                                                          $  35,249,038
=======================================================================================================
Shares Outstanding:
  Class A                                                                                       884,827
-------------------------------------------------------------------------------------------------------
  Class B                                                                                       853,959
-------------------------------------------------------------------------------------------------------
  Class L                                                                                       136,642
-------------------------------------------------------------------------------------------------------
Net Asset Value:
  Class A (and redemption price)                                                          $       19.23
-------------------------------------------------------------------------------------------------------
  Class B *                                                                               $       18.39
-------------------------------------------------------------------------------------------------------
  Class L **                                                                              $       18.46
-------------------------------------------------------------------------------------------------------
Maximum Public Offering Price Per Share:
  Class A (net asset value plus 5.26% of net asset value per share)                       $       20.24
-------------------------------------------------------------------------------------------------------
  Class L (net asset value plus 1.01% of net asset value per share)                       $       18.65
=======================================================================================================
</TABLE>

*  Redemption price is NAV of Class B shares reduced by a 5.00% CDSC if shares
   are redeemed within one year from initial purchase (See Note 2).

** Redemption price is NAV of Class L shares reduced by a 1.00% CDSC if shares
   are redeemed within the first year of purchase.

                      See Notes to Financial Statements.

 9  Smith Barney Natural Resources Fund  | 2000 Annual Report to Shareholders
<PAGE>

<TABLE>
<CAPTION>
==========================================================================================================
  Statement of Operations                                              For the Year Ended October 31, 2000
==========================================================================================================
<S>                                                                  <C>
INVESTMENT INCOME:
  Dividends                                                                               $     736,473
  Interest                                                                                       37,079
  Less: Foreign withholding tax                                                                  (9,192)
-------------------------------------------------------------------------------------------------------
  Total Investment Income                                                                       764,360
-------------------------------------------------------------------------------------------------------
EXPENSES:
  Management fees (Note 2)                                                                      326,909
  Distribution fees (Note 2)                                                                    284,064
  Shareholder and system servicing fees                                                         108,658
  Audit and legal                                                                                53,946
  Shareholder communications                                                                     47,376
  Registration fees                                                                              37,377
  Directors' fees                                                                                26,540
  Custody                                                                                         7,410
  Other                                                                                           5,734
-------------------------------------------------------------------------------------------------------
  Total Expenses                                                                                898,014
-------------------------------------------------------------------------------------------------------
Net Investment Loss                                                                            (133,654)
-------------------------------------------------------------------------------------------------------
REALIZED AND UNREALIZED GAIN (LOSS) ON
INVESTMENTS AND FOREIGN CURRENCIES (NOTE 3):
  Realized Loss From:
     Security transactions (excluding short-term securities)                                 (4,220,767)
     Foreign currency transactions                                                               (3,223)
-------------------------------------------------------------------------------------------------------
  Net Realized Loss                                                                          (4,223,990)
-------------------------------------------------------------------------------------------------------
  Change in Net Unrealized Appreciation (Depreciation) of Investments:
     Beginning of year                                                                       (1,281,749)
     End of year                                                                              4,271,916
-------------------------------------------------------------------------------------------------------
  Increase in Net Unrealized Appreciation                                                     5,553,665
-------------------------------------------------------------------------------------------------------
Net Gain on Investments and Foreign Currencies                                                1,329,675
-------------------------------------------------------------------------------------------------------
Increase in Net Assets From Operations                                                    $   1,196,021
=======================================================================================================
</TABLE>

                      See Notes to Financial Statements.

 10  Smith Barney Natural Resources Fund  | 2000 Annual Report to Shareholders

<PAGE>

<TABLE>
<CAPTION>
=======================================================================================================================
Statements of Changes in Net Assets                                                  For the Years Ended October 31,
=======================================================================================================================
                                                                                        2000                     1999
=======================================================================================================================
<S>                                                                           <C>                        <C>
OPERATIONS:
     Net investment income (loss)                                             $      (133,654)           $       18,905
     Net realized loss                                                             (4,223,990)                 (318,093)
     Increase in net unrealized appreciation                                        5,553,665                 7,443,234
-----------------------------------------------------------------------------------------------------------------------
     Increase in Net Assets From Operations                                         1,196,021                 7,144,046
-----------------------------------------------------------------------------------------------------------------------
FUND SHARE TRANSACTIONS (NOTE 10):
     Net proceeds from sale of shares                                              87,287,728               195,787,393
     Cost of shares reacquired                                                   (101,221,864)             (214,496,322)
-----------------------------------------------------------------------------------------------------------------------
     Decrease in Net Assets From Fund Share Transactions                          (13,934,136)              (18,708,929)
-----------------------------------------------------------------------------------------------------------------------
Decrease in Net Assets                                                            (12,738,115)              (11,564,883)

NET ASSETS:
     Beginning of year                                                             47,987,153                59,552,036
-----------------------------------------------------------------------------------------------------------------------
     End of year*                                                             $    35,249,038            $   47,987,153
=======================================================================================================================
* Includes undistributed net investment income of:                            $         4,416            $        4,896
=======================================================================================================================
</TABLE>

                      See Notes to Financial Statements.

11   Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

================================================================================
Notes to Financial Statements
================================================================================

1.  Significant Accounting Policies

Smith Barney Natural Resources Fund ("Portfolio"), a separate diversified,
open-end investment Portfolio of Smith Barney Sector Series Inc. ("Fund"), a
Maryland corporation, is registered under the Investment Company Act of 1940, as
amended. The Fund consists of this Portfolio and six other separate investment
portfolios: Smith Barney Financial Services Fund, Smith Barney Health Sciences
Fund, Smith Barney Technology Fund, Smith Barney Global Biotechnology Fund,
Smith Barney Global Technology Fund and Smith Barney Global Media &
Telecommunications Fund. The financial statements and financial highlights for
the other portfolios are presented in separate shareholder reports.

The significant accounting policies followed by the Portfolio are: (a) security
transactions are accounted for on trade date; (b) securities traded in national
securities markets are valued at the closing prices in the primary exchange on
which they are traded; securities listed or traded on certain foreign exchanges
or other markets whose operations are similar to the U.S. over-the-counter
market (including securities listed on exchanges where the primary market is
believed to be over-the-counter) and securities for which no sale was reported
on that date are valued at the mean between the bid and ask prices. Securities
which are listed or traded on more than one exchange or market are valued at the
quotations on the exchange or market determined to be the primary market for
such securities. Gold bullion is valued at the daily London afternoon fixing;
(c) securities for which market quotations are not available will be valued in
good faith at fair market value by or under the direction of the Board of
Directors; (d) securities maturing within 60 days are valued at cost plus
accreted discount, or minus amortized premium, which approximates value; (e) the
accounting records of the Portfolio are maintained in U.S. dollars. All assets
and liabilities denominated in foreign currencies are translated into U.S.
dollars based on the rate of exchange of such currencies against U.S. dollars on
the date of valuation. Purchases and sales of securities, and income and
expenses are translated at the rate of exchange quoted on the respective date
that such transactions are recorded. Differences between income or expense
amounts recorded and collected or paid are adjusted when reported by the
custodian; (f) interest income, adjusted for amortization of premium and
accretion of discount, is recorded on an accrual basis; (g) dividend income is
recorded on the ex-dividend date; foreign dividends are recorded on the ex-
dividend date or as soon as practical after the Portfolio determines the
existence of a dividend declaration after exercising reasonable due diligence;
(h) dividends and distributions to shareholders are recorded on the ex-dividend
date; (i) gains or losses on the sale of securities are calculated by using the
specific identification method; (j) direct expenses are charged to each class;
management fees and general expenses are allocated on the basis of relative net
assets; (k) the character of income and gains to be distributed are determined
in accordance with income tax regulations which may differ from generally
accepted accounting principles. At October 31, 2000, reclassifications were made
to the Portfolio's capital accounts to reflect permanent book/tax differences
and income and gains available for distributions under income tax regulations.
Accordingly, a portion of accumulated net realized loss and accumulated net
investment loss amounting to $1,319,840 and $136,988, respectively, was
reclassified to paid-in capital. Net investment income, net realized gains and
net assets were not affected by this adjustment; (l) the Portfolio intends to
comply with the requirements of the Internal Revenue Code of 1986, as amended,
pertaining to regulated investment companies and to make distributions of
taxable income sufficient to relieve it from substantially all Federal income
and excise taxes; and (m) estimates and assumptions are required to be made
regarding assets, liabilities and changes in net assets resulting from
operations when financial statements are prepared. Changes in the economic
environment, financial markets and any other parameters used in determining
these estimates could cause actual results to differ.

In addition, the Portfolio may enter into forward exchange contracts in order to
hedge against foreign currency risk. These contracts are marked-to-market daily,
by recognizing the difference between the contract exchange rate and the current
market rate as an unrealized gain or loss. Realized gains or losses are
recognized when contracts are settled.

12   Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

================================================================================
Notes to Financial Statements (continued)
================================================================================

2.  Management Agreement and Other Transactions

SSB Citi Fund Management LLC ("SSBC"), a subsidiary of Salomon Smith Barney
Holdings Inc. ("SSBH"), which, in turn is a subsidiary of Citigroup Inc.
("Citigroup"), acts as investment manager to the Portfolio. The Portfolio pays
SSBC a management fee calculated at an annual rate of 0.75% of the average daily
net assets. This fee is calculated daily and paid monthly.

Citi Fiduciary Trust Company ("CFTC"), another subsidiary of Citigroup, acts as
the Portfolio's transfer agent and PFPC Global Fund Services ("PFPC") acts as
the Portfolio's sub-transfer agent. CFTC receives account fees and asset-based
fees that vary according to the size and type of account. PFPC is responsible
for shareholder recordkeeping and financial processing for all shareholder
accounts and is paid by CFTC. For the year ended October 31, 2000, the Portfolio
paid transfer agent fees of $93,642 to CFTC.

Effective June 5, 2000, Salomon Smith Barney Inc. ("SSB"), another subsidiary of
SSBH, became the Portfolio's distributor replacing CFBDS, Inc. ("CFBDS"). In
addition, SSB acts as the primary broker for the Portfolio's agency
transactions. Certain other broker-dealers, continue to sell Portfolio shares to
the public as members of the selling group. For the year ended October 31, 2000,
SSB received brokerage commissions of $18,111.

There are maximum initial sales charges of 5.00% and 1.00% for Class A and L
shares, respectively. There is a contingent deferred sales charge ("CDSC") of
5.00% on Class B shares, which applies if redemption occurs within one year from
initial purchase and declines thereafter by 1.00% per year until no CDSC is
incurred. Class L shares are being sold at net asset value plus a maximum
initial sales charge of 1.00%. Class L shares also have a 1.00% CDSC, which
applies if redemption occurs within the first year of purchase. In certain
cases, Class A shares have a 1.00% CDSC, which applies if redemption occurs
within the first year of purchase. This CDSC only applies to those purchases of
Class A shares, which, when combined with current holdings of Class A shares,
equal or exceed $500,000 in the aggregate. These purchases do not incur an
initial sales charge.

For the year ended October 31, 2000, CDSC's paid to SSB and sales charges
received by SSB and CFBDS were approximately:

                        Class A            Class B       Class L
================================================================================
CDSCs                      --              $ 57,000         --
--------------------------------------------------------------------------------
Sales Charges           $ 15,000               --        $  8,000
================================================================================

Pursuant to a Distribution Plan, the Portfolio pays a service fee with respect
to Class A, B and L shares calculated at an annual rate of 0.25% of the average
daily net assets of each respective class. The Portfolio also pays a
distribution fee with respect to Class B and L shares calculated at an annual
rate of 0.75% of the average daily net assets for each class, respectively.

For the year ended October 31, 2000, total Distribution Plan fees incurred were:

                          Class A        Class B       Class L
================================================================================
Distribution Plan Fees    $ 50,605       $204,325      $ 29,134
================================================================================

All officers and one Director of the Fund are employees of SSB.

  13 Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

================================================================================
Notes to Financial Statements (continued)
================================================================================

3.  Investments

During the year ended October 31, 2000, the aggregate cost of purchases and
proceeds from sales of investments (including maturities, but excluding
short-term securities) were as follows:

================================================================================
Purchases                                                 $26,192,780
--------------------------------------------------------------------------------
Sales                                                      39,898,741
================================================================================

At October 31, 2000, aggregate gross unrealized appreciation and depreciation of
investments for Federal income tax purposes were substantially as follows:

================================================================================
Gross unrealized appreciation                             $ 5,983,392
Gross unrealized depreciation                              (1,711,476)
--------------------------------------------------------------------------------
Net unrealized appreciation                               $ 4,271,916
================================================================================

4.  Futures Contracts

Initial margin deposits made upon entering into futures contracts are recognized
as assets. Securities equal to the initial margin amount are segregated by the
custodian in the name of the broker. Additional securities are also segregated
up to the current market value of the futures contract. During the period the
futures contract is open, changes in the value of the contract are recognized as
unrealized gains or losses by "marking to market" on a daily basis to reflect
the market value of the contract at the end of each day's trading. Variation
margin payments are received or made and recognized as assets due from or
liabilities due to broker, depending upon whether unrealized gains or losses are
incurred. When the contract is closed, the Portfolio records a realized gain or
loss equal to the difference between the proceeds from (or cost of) the closing
transaction and the Portfolio's basis in the contract.

The Portfolio enters into such contracts to hedge a portion of its portfolio.
The Portfolio bears the market risk that arises from changes in the value of the
financial instruments and securities indices (futures contracts).

At October 31, 2000, there were no open futures contracts.

5.  Options Contracts

Premiums paid when put or call options are purchased by the Portfolio, represent
investments, which are marked-to-market daily and are included in the schedule
of investments. When a purchased option expires, the Portfolio will realize a
loss in the amount of the premium paid. When the Portfolio enters into a closing
sales transaction, the Portfolio will realize a gain or loss depending on
whether the proceeds from the closing sales transaction are greater or less than
the premium paid for the option. When the Portfolio exercises a put option, it
will realize a gain or loss from the sale of the underlying security and the
proceeds from such sale will be decreased by the premium originally paid. When
the Portfolio exercises a call option, the cost of the security which the
Portfolio purchases upon exercise will be increased by the premium originally
paid.

At October 31, 2000, the Portfolio held no purchased call or put option
contracts.

When the Portfolio writes a covered call or put option, an amount equal to the
premium received by the Portfolio is recorded as a liability, the value of which
is marked-to-market daily. When a written option expires, the Portfolio realizes
a gain equal to the amount of the premium received. When the Portfolio enters
into a closing purchase transaction, the Portfolio realizes a gain or loss
depending upon whether the cost of the closing transaction is greater or less
than the premium originally received, without regard to any unrealized gain or
loss on the underlying security, and the liability related to such option is
eliminated. When a written call option is exercised, the cost of the security
sold will be decreased by the premium originally received. When a written put
option is exercised, the amount of the premium originally received will reduce
the cost of the security which the Portfolio purchased upon exercise. When
written index options are exercised, settlement is made in cash. The risk
associated with purchasing options is limited to the premium originally paid.
The Portfolio enters into options for hedging

  14 Smith Barney Natural Resources Fund | 2000 Annual Report to Shareholders
<PAGE>

================================================================================
Notes to Financial Statements (continued)
================================================================================

purposes. The risk in writing a covered call option is that the Portfolio gives
up the opportunity to participate in any increase in the price of the underlying
security beyond the exercise price. The risk in writing a put option is that the
Portfolio is exposed to the risk of loss if the market price of the underlying
security declines.

During the year ended October 31, 2000, the Portfolio did not enter into any
written covered call or put option contracts.

6.  Lending of Portfolio Securities

The Portfolio has an agreement with its custodian whereby the custodian may lend
securities owned by the Portfolio to brokers, dealers and other financial
organizations. Fees earned by the Portfolio on securities lending are recorded
as interest income. Loans of securities by the Portfolio are collateralized by
cash, U.S. government securities or high quality money market instruments that
are maintained at all times in an amount at least equal to the current market
value of the loaned securities, plus a margin depending on the type of
securities loaned. The custodian establishes and maintains the collateral in a
segregated account. The Portfolio maintains exposure for the risk of any losses
in the investment of amounts received as collateral.

At October 31, 2000, the Portfolio loaned common stock having a value of
$1,524,348 and holds the following collateral for loaned securities:

Security Description                                                  Value
=============================================================================
Commercial Paper:
   Associates Corp. of North America, 6.651% due 11/1/00           $   85,117
   GE Capital International, 6.661% due 11/1/00                        85,361
   UBS Finance (Delaware) Inc., 6.651% due 11/1/00                     85,117
Repurchase Agreements:

   Bear Stearns, 6.680% due 11/1/00                                   163,702
   CS First Boston Corp., 6.680% due 11/1/00                          183,476
   J.P. Morgan Securities, 6.700% due 11/1/00                          85,133
   Morgan Stanley, 6.605% due 11/1/00                                 183,476
Time Deposits:

   Banco Santander CH SA, London, 6.660% due 11/1/00                   85,133
   Bank of Austria, 6.656% due 11/1/00                                 85,133
   Bank of Ireland, 6.688% due 11/1/00                                 85,133
   Banque Bruxelles Lambert, London, 6.656% due 11/1/00                85,133
   Barclays Bank PLC, 6.660% due 11/1/00                               85,133
   Caisse de Depots et Consign, Paris, 6.656% due 11/1/00              85,133
   Firstar Bank, G.C., 6.656% due 11/1/00                              85,377


Security Description (continued)                                       Value
=============================================================================
Time Deposits:
   Nordeutsche Landesbank, Singapore, 6.656% due 11/1/00           $   85,133
   Toronto Dominion, London, 6.660% due 11/1/00                        85,133
   Wells Fargo Bank, Minnesota N.A., GC, 6.656% due 11/1/00            85,377
-----------------------------------------------------------------------------
Total                                                              $1,723,200
=============================================================================

Income earned from securities lending for the year ended October 31, 2000 was
$6,462.

7.  Repurchase Agreements

The Portfolio purchases (and its custodian takes possession of) U.S. government
securities from banks and securities dealers subject to agreements to resell the
securities to the sellers at a future date (generally, the next business day) at
an agreed upon higher repurchase price. The Portfolio requires continual
maintenance of the market value of the collateral (plus accrued interest) in
amounts at least equal to the repurchase price.

8.  Concentration of Risk

The Portfolio intends to invest at least 65% of its assets in natural resource-
related investments. As a result of this concentration policy, which is a
fundamental policy of the Portfolio, the Portfolio's investment may be subject
to greater risk and market fluctuation than a fund that invests in securities
representing a broader range of investment alternatives.

The Portfolio's investments in foreign securities may involve risks not present
in domestic investments. Since securities may be denominated in a foreign
currency and may require settlement in foreign currencies and pay interest or
dividends in foreign currencies, changes in the relationship of these foreign
currencies to the U.S. dollar can significantly affect the value of these
investments and earnings of the Portfolio. Foreign investments may also subject
the Fund to foreign government exchange restrictions, expropriation, taxation or
other political, social or economic developments, all of which could affect the
market and/or credit risk of the investments.

15  Smith Barney Natural Resources Fund   | 2000 Annual Report to Shareholders

                                       15
<PAGE>

================================================================================
Notes to Financial Statements (continued)
================================================================================

9.  Capital Loss Carryforward

At October 31, 2000, the Portfolio had, for Federal income tax purposes,
approximately $ 18,154,000 of capital loss carry- forwards available to offset
any future realized capital gains. To the extent that these carryforward losses
are used to offset capital gains, it is probable that the gains so offset will
not be distributed. The amount and year of the expiration for each carryforward
loss is indicated below:

                                            2006           2007          2008
================================================================================
Carryforward Amounts                    $12,873,000     $884,000     $4,397,000
================================================================================

10. Capital Shares

At October 31, 2000, the Fund had three billion shares of capital stock
authorized with a par value of $ 0.001 per share. The Portfolio has the ability
to issue multiple classes of shares. Each share of a class represents an
identical interest in the Portfolio and has the same rights, except that each
class bears certain expenses specifically related to the distribution of its
shares.

At October 31, 2000, total paid-in capital amounted to the following for each
class:

                                         Class A       Class B       Class L
================================================================================
Total Paid-in Capital                  $33,578,182   $12,895,129   $2,716,539
================================================================================

Transactions in shares of each class were as follows:

<TABLE>
<CAPTION>
                                        Year Ended                         Year Ended
                                     October 31, 2000                   October 31, 1999
                              -----------------------------       ----------------------------
                                Shares           Amount            Shares           Amount
==============================================================================================
<S>                           <C>              <C>                <C>             <C>
Class A
Shares sold                    3,987,960       $ 79,167,747        9,164,942      $173,366,391
Shares reacquired             (4,220,531)       (83,858,673)      (9,687,078)      183,016,775)
----------------------------------------------------------------------------------------------
Net Decrease                    (232,571)      $ (4,690,926)        (522,136)     $ (9,650,384)
==============================================================================================

Class B
Shares sold                      298,227       $  5,757,486        1,093,758      $ 20,260,718
Shares reacquired               (763,221)       (14,511,305)      (1,606,176)      (28,799,467)
----------------------------------------------------------------------------------------------
Net Decrease                    (464,994)      $ (8,753,819)        (512,418)     $ (8,538,749)
==============================================================================================

Class L
Shares sold                      127,383       $  2,362,495          119,290      $  2,160,284
Shares reacquired               (154,586)        (2,851,886)        (148,607)       (2,680,080)
----------------------------------------------------------------------------------------------
Net Decrease                     (27,203)      $   (489,391)         (29,317)     $   (519,796)
==============================================================================================
</TABLE>

 16  Smith Barney Natural Resources Fund  | 2000 Annual Report to Shareholders

                                       16
<PAGE>

================================================================================
Financial Highlights
================================================================================

For a share of each class of capital stock outstanding throughout each year
ended October 31:

<TABLE>
<CAPTION>
Class A Shares                                  2000/(1)/   1999/(1)/    1998/(1)/           1997           1996/(1)/
=======================================================================================================================
<S>                                             <C>         <C>          <C>               <C>              <C>
Net Asset Value, Beginning of Year              $  18.85    $  16.56     $  23.23          $  22.95         $  16.50
-----------------------------------------------------------------------------------------------------------------------
Income (Loss) From Operations:

   Net investment income (loss)                     0.01        0.05        (0.01)            (0.12)            0.08
   Net realized and unrealized gain (loss)          0.37        2.24        (6.50)             0.73             6.37
-----------------------------------------------------------------------------------------------------------------------
Total Income (Loss) From Operations                 0.38        2.29        (6.51)             0.61             6.45
-----------------------------------------------------------------------------------------------------------------------
Less Distributions From:
   Net investment income                              --          --           --             (0.33)              --
   Net realized gains                                 --          --        (0.16)               --               --
-----------------------------------------------------------------------------------------------------------------------
Total Distributions                                   --          --        (0.16)            (0.33)              --
-----------------------------------------------------------------------------------------------------------------------
Net Asset Value, End of Year                    $  19.23    $  18.85     $  16.56          $  23.23         $  22.95
-----------------------------------------------------------------------------------------------------------------------
Total Return                                        2.02%      13.83%      (28.13)%            2.67%           39.09%
-----------------------------------------------------------------------------------------------------------------------
Net Assets, End of Year (000s)                  $ 17,019    $ 21,069     $ 27,147          $ 45,488         $ 50,521
-----------------------------------------------------------------------------------------------------------------------
Ratios to Average Net Assets:
   Expenses                                         1.71%       1.73%        1.57%             1.51%            1.62%
   Net investment income (loss)                     0.04        0.27        (0.05)            (0.32)            0.15
-----------------------------------------------------------------------------------------------------------------------
Portfolio Turnover Rate                               62%        133%         151%              101%             120%
=======================================================================================================================
</TABLE>

(1) Per share amounts have been calculated using the monthly average shares
method.

17  Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

================================================================================
Financial Highlights (continued)
================================================================================

For a share of each class of capital stock outstanding throughout each year
ended October 31:

<TABLE>
<CAPTION>
Class B Shares                                        2000/(1)/  1999/(1)/    1998/(1)/        1997          1996/(1)/
=======================================================================================================================
<S>                                                   <C>        <C>          <C>           <C>              <C>
Net Asset Value, Beginning of Year                     $ 18.15    $  16.00     $  22.60     $  22.32         $  16.15
-----------------------------------------------------------------------------------------------------------------------
Income (Loss) From Operations:
   Net investment loss                                   (0.12)      (0.03)       (0.13)       (0.27)           (0.09)
   Net realized and unrealized gain (loss)                0.36        2.18        (6.31)        0.70             6.26
-----------------------------------------------------------------------------------------------------------------------
Total Income (Loss) From Operations                       0.24        2.15        (6.44)        0.43             6.17
-----------------------------------------------------------------------------------------------------------------------
Less Distributions From:
   Net investment income                                    --          --           --        (0.15)              --
   Net realized gains                                       --          --        (0.16)          --               --
-----------------------------------------------------------------------------------------------------------------------
Total Distributions                                         --          --        (0.16)       (0.15)              --
-----------------------------------------------------------------------------------------------------------------------
Net Asset Value, End of Year                           $ 18.39    $  18.15     $  16.00     $  22.60         $  22.32
-----------------------------------------------------------------------------------------------------------------------
Total Return                                              1.32%      13.44%      (28.61)%       1.95%           38.20%
-----------------------------------------------------------------------------------------------------------------------
Net Assets, End of Year (000s)                         $15,708    $ 23,937     $ 29,309     $ 66,819         $ 73,969
-----------------------------------------------------------------------------------------------------------------------
Ratios to Average Net Assets:
   Expenses                                               2.38%       2.42%        2.23%        2.18%            2.29%
   Net investment loss                                   (0.61)      (0.17)       (0.71)       (0.99)           (0.83)
-----------------------------------------------------------------------------------------------------------------------
Portfolio Turnover Rate                                     62%        133%         151%         101%             120%
=======================================================================================================================
</TABLE>

(1) Per share amounts have been calculated using the monthly average shares
method.

18  Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>


================================================================================
Financial Highlights (continued)
================================================================================

For a share of each class of capital stock outstanding throughout each year
ended October 31:

<TABLE>
<CAPTION>

Class L Shares                                          2000/(1)/     1999/(1)/     1998/(1)(2)/     1997          1996/(1)/
===============================================================================================================================
<S>                                                     <C>           <C>           <C>            <C>             <C>
Net Asset Value, Beginning of Year                      $   18.20     $   16.03      $   22.62     $   22.32       $   16.16
-------------------------------------------------------------------------------------------------------------------------------
Income (Loss) From Operations:
   Net investment income (loss)                             (0.11)        (0.02)         (0.12)        (0.23)           0.05
   Net realized and unrealized gain (loss)                   0.37          2.19          (6.31)         0.68            6.11
-------------------------------------------------------------------------------------------------------------------------------
Total Income (Loss) From Operations                          0.26          2.17          (6.43)         0.45            6.16
-------------------------------------------------------------------------------------------------------------------------------
Less Distributions From:
   Net investment income                                       --            --             --         (0.15)             --
   Net realized gains                                          --            --          (0.16)           --              --
-------------------------------------------------------------------------------------------------------------------------------
Total Distributions                                            --            --          (0.16)        (0.15)             --
-------------------------------------------------------------------------------------------------------------------------------
Net Asset Value, End of Year                            $   18.46     $   18.20      $   16.03     $   22.62       $   22.32
-------------------------------------------------------------------------------------------------------------------------------
Total Return                                                 1.43%        13.54%        (28.54)%        2.04%          38.12%
-------------------------------------------------------------------------------------------------------------------------------
Net Assets, End of Year (000s)                          $   2,522     $   2,981      $   3,096     $   6,393       $   7,602
-------------------------------------------------------------------------------------------------------------------------------
Ratios to Average Net Assets:
   Expenses                                                  2.30%         2.33%          2.17%         2.12%           2.25%
   Net investment loss                                      (0.56)        (0.09)         (0.63)        (0.92)          (0.21)
-------------------------------------------------------------------------------------------------------------------------------
Portfolio Turnover Rate                                        62%          133%           151%          101%            120%
===============================================================================================================================
</TABLE>

(1) Per share amounts have been calculated using the monthly average shares
method.

(2) On June 12, 1998, Class C shares were renamed Class L shares.

19  Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

===============================================================================
Independent Auditors' Report
===============================================================================

The Shareholders and Board of Directors of
Smith Barney Natural Resources Fund:

We have audited the accompanying statement of assets and liabilities, including
the schedule of investments, of Smith Barney Natural Resources Fund of Smith
Barney Sector Series Inc. as of October 31, 2000, and the related statement of
operations for the year then ended, the statements of changes in net assets for
each of the years in the two-year period then ended, and the financial
highlights for each of the years in the five-year period then ended. These
financial statements and financial highlights are the responsibility of the
Fund's management. Our responsibility is to express an opinion on these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States of America. Those standards require that we plan and
perform the audit to obtain reasonable assurance about whether the financial
statements and financial highlights are free of material misstatement. An audit
includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements. Our procedures included confirmation of
securities owned as of October 31, 2000, by correspondence with the custodian.
As to securities purchased but not yet received, we performed other appropriate
auditing procedures. An audit also includes assessing the accounting principles
used and significant estimates made by management, as well as evaluating the
overall financial statement presentation. We believe that our audits provide a
reasonable basis for our opinion.

In our opinion, the financial statements and financial highlights referred to
above present fairly, in all material respects, the financial position of Smith
Barney Natural Resources Fund as of October 31, 2000, and the results of its
operations for the year then ended, the changes in its net assets for each of
the years in the two-year period then ended, and the financial highlights for
each of the years in the five-year period then ended, in conformity with
accounting principles generally accepted in the United States of America.


                                                                      KPMG LLP


New York, New York
December 11, 2000

20  Smith Barney Natural Resources Fund  |  2000 Annual Report to Shareholders
<PAGE>

 SMITH BARNEY
NATURAL RESOURCES FUND

<TABLE>
                                     <S>                                 <C>
                                     DIRECTORS                           INVESTMENT MANAGER
                                     Herbert Barg                        SSB Citi Fund Management LLC
                                     Alfred J. Bianchetti
                                     Martin Brody                        DISTRIBUTOR
                                     Dwight B. Crane                     Salomon Smith Barney Inc.
                                     Burt N. Dorsett
                                     Elliot S. Jaffe                     CUSTODIAN
                                     Stephen E. Kaufman                  The Chase Manhattan Bank, N.A.
                                     Joseph J. McCann
                                     Heath B. McLendon, Chairman
                                     Cornelius C. Rose, Jr.              TRANSFER AGENT
                                                                         Citi Fiduciary Trust Company
                                     James J. Crisona, Emeritus          125 Broad Street, 11th Floor
                                                                         New York, New York 10004

                                     OFFICERS
                                     Heath B. McLendon                   SUB-TRANSFER AGENT
                                     President and                       PFPC Global Fund Services
                                     Chief Executive Officer             P.O. Box 9699
                                                                         Providence, Rhode Island
                                     Lewis E. Daidone                    02940-9699
                                     Senior Vice President
                                     and Treasurer

                                     John G. Goode
                                     Vice President and
                                     Investment Officer

                                     Paul A. Brook
                                     Controller

                                     Christina T. Sydor
                                     Secretary

</TABLE>
<PAGE>

Smith Barney Natural Resources Fund

                                             This report is submitted for the
                                             general information of shareholders
                                             of Smith Barney Sector Series Inc.
                                             -- Smith Barney Natural Resources
                                             Fund, but it may also be used as
                                             sales literature when preceded or
                                             accompanied by the current
                                             Prospectus, which gives details
                                             about charges, expenses, investment
                                             objectives and operating policies
                                             of the Portfolio. If used as sales
                                             material after January 31, 2001,
                                             this report must be accompanied by
                                             performance information for the
                                             most recently completed calendar
                                             quarter.

                                             SMITH BARNEY NATURAL RESOURCES FUND
                                             Smith Barney Mutual Funds
                                             388 Greenwich Street, MF-2
                                             New York, New York 10013


                                             For complete information on any
                                             Smith Barney Mutual Funds,
                                             including management fees and
                                             expenses, call or write your
                                             financial professional for a free
                                             prospectus. Read it carefully
                                             before you invest or send money.

                                             www.smithbarney.com/mutualfunds







                                             Salomon Smith Barney
                                             --------------------------
                                                A member of citigroup


                                             Salomon Smith Barney is a
                                             registered service mark of
                                             Salomon Smith Barney Inc.



© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission