BIORELEASE CORP
PRE 14A, 1996-11-18
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                November 14, 1996



Securities and Exchange Commission
450 Fifth Street N.W.
Washington, D.C.  20549

                                    Re:     Biorelease Corp.
                                            SEC File No. 0-15260

Dear Sir or Madam:

         In connection  with the EDGAR filing of Preliminary  Proxy materials by
Biorelease  Corp.  (the  "Company"),  I draw  your  attention  to page 26 of the
Preliminary Proxy Statement, and the section entitled "Documents Incorporated by
Reference."  The Company  incorporates  by reference  the  financial  statements
contained  in the  Annual  Report to  Stockholders  which is not filed  with the
preliminary  proxy  materials.  Those  financial  statements may be found in the
Company's  Form  10-KSB  for the fiscal  year  ended June 30,  1996 and the Form
10-QSB for the quarter ended  September 30, 1996,  both of which have been filed
with the Commission.

                                                     Very truly yours,



                                                     John B. Lowy


<PAGE>

PRELIMINARY COPY
BIORELEASE CORP.
ANNUAL MEETING OF STOCKHOLDERS
JANUARY 6, 1997

                    PROXY SOLICITED BY THE BOARD OF DIRECTORS

         THE UNDERSIGNED  hereby appoints  RICHARD  SCHUBERT,  proxy,  with full
power of  substitution,  to vote all  shares of the  undersigned  at the  Annual
Meeting of Stockholders of Biorelease Corp. (the  "Company"),  to be held at the
offices of Berry Dunn McNeil & Parker,  900 Elm Street,  9th Floor,  Manchester,
New  Hampshire  03101,  on January 6, 1997 at 1:00  P.M.,  and all  adjournments
thereof, upon the following matters:

1.       ELECTION OF DIRECTORS.

FOR nominees listed below (  ) WITHHOLD Authority for all nominees (  )
(except as written below)

                  Donald E. Strange                           Nigel Fleming
                  Richard Schubert                            Richard Whitney
                  Paul Leibowitz

INSTRUCTION:  To withhold  authority to vote for any individual  nominee,  write
that nominee's name in the space provided below:





2.       AMENDMENT OF THE CERTIFICATE OF INCORPORATION TO AUTHORIZE 10,000,000
         SHARES OF PREFERRED STOCK.

FOR ( ) AGAINST ( ) ABSTAIN ( ) the  amendment of the Company's  Certificate  of
Incorporation to authorize 10,000,000 shares of Preferred Stock, $.01 par value.



3.       APPROVAL OF THE ACQUISITION OF TheraMed PARTNERS, INC.

FOR ( )  AGAINST  ( )  ABSTAIN  ( ) the  acquisition  of all of the  issued  and
outstanding shares of TheraMed Partners, Inc.

<PAGE>


4.       AMENDMENT OF THE CERTIFICATE OF INCORPORATION TO CHANGE THE
         COMPANY'S NAME TO "PHARMATRAGE HOLDINGS, INC."

FOR ( ) AGAINST ( ) ABSTAIN ( ) the  amendment of the Company's  Certificate  of
Incorporation to change the Company's name to "Pharmatrage Holdings, Inc."

5.       REVERSE SPLIT OF THE COMPANY'S ISSUED AND OUTSTANDING SHARES OF
         COMMON STOCK ON A ONE-FOR-FOUR BASIS.

FOR ( ) AGAINST ( ) ABSTAIN ( ) the reverse  split of the  Company's  issued and
outstanding shares of Common Stock on a one-for-four basis,  reducing the issued
and outstanding  shares from 9,471,659 to  approximately  2,367,915;  fractional
shares being increased to the next whole share.

6.       SPIN OFF OF ALL SHARES OF BIORELEASE TECHNOLOGIES, INC. HELD BY THE
         COMPANY TO THE COMPANY'S (PRE-TheraMed ACQUISITION) STOCKHOLDERS.

FOR ( )  AGAINST  ( )  ABSTAIN  ( ) the spin  off of all  shares  of  Biorelease
Technologies, Inc. held by the Company to the Company's stockholders (the record
date being the day prior to the date of consummation  of the TheraMed  Partners,
Inc. acquisition).

7.       RATIFICATION OF THE SELECTION OF INDEPENDENT PUBLIC ACCOUNTANTS

FOR ( )  AGAINST ( ) ABSTAIN ( ) the  ratification  of the  selection  of Berry,
Dunn,  McNeil  &  Parker,  Manchester,  New  Hampshire,  as  independent  public
accountants of the Company for the 1997 fiscal year.

         In his discretion,  the proxy named herein is authorized to vote on any
other matters which may properly come before this meeting.

         The shares  represented  hereby  will be voted in  accordance  with the
specifications  of this proxy. If not otherwise  specified,  this proxy is to be
voted in favor of the nominees for Directors named in the Proxy Statement and in
favor of all of the other above listed proposals.  Attendance of the undersigned
at the meeting or at any adjourned  session thereof will not be deemed to revoke
this proxy unless the undersigned shall indicate at the meeting the intention of
the undersigned to vote said shares in person.

Dated:                   , 199_.

                                    ------------------------------------
Name (Please Print)                                           Signature

                                    ------------------------------------
Name (Please Print)                                           Signature

         Please sign exactly as your shares are registered.  For joint accounts,
each co-owner should sign. When signing in a fiduciary  representative capacity,
please give your full title as such.

         PLEASE  FILL IN,  DATE,  SIGN AND  RETURN  THIS  PROXY IN THE  ENCLOSED
POSTAGE-PAID ENVELOPE.

                                       -2-


<PAGE>


                                BIORELEASE CORP.
                                10 Chestnut Drive
                                Bedford, NH 03110


                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS


                          Meeting Date: January 6, 1997

         NOTICE IS HEREBY GIVEN, that the 1996 Annual Meeting of Stockholders of
BIORELEASE  CORP., a Delaware  corporation (the "Company"),  will be held at the
offices of Berry Dunn McNeil & Parker,  900 Elm Street,  9th Floor,  Manchester,
New  Hampshire  03101,  on  January  6, 1997 at 1:00 in the  afternoon,  for the
following purposes:

          1.   To elect five Directors of the Company;

          2.   To  consider  and act  upon a  proposal  to amend  the  Company's
               Certificate of  Incorporation to authorize  10,000,000  shares of
               Preferred Stock, $.01 par value.

          3.   To consider  and act upon a proposal to acquire all of the issued
               and outstanding shares of TheraMed Partners, Inc.

          4.   To  consider  and act  upon a  proposal  to amend  the  Company's
               Certificate  of  Incorporation  to change the  Company's  name to
               "Pharmatrage Holdings, Inc."

          5.   To  consider  and  act  upon a  proposal  to  reverse  split  the
               Company's  issued  and  outstanding  shares of Common  Stock on a
               one-for-four basis; fractional shares being increased to the next
               whole share.

          6.   To  consider  and act upon a  proposal  to spin off all shares of
               Biorelease  Technologies,   Inc.  held  by  the  Company  to  the
               Company's  (pre-TheraMed  acquisition)  stockholders  (the record
               date  being  the day  prior  to the date of  consummation  of the
               TheraMed Partners, Inc. acquisition).

          7.   To consider  and act upon a proposal to ratify the  selection  of
               Berry, Dunn, McNeil & Parker,  Manchester,  New Hampshire, as the
               independent public accountants for the 1997 fiscal year; and

          8.   To transact  such other  business as may properly come before the
               meeting or any adjournments thereof.

     CONSUMMATION  OF  THE  ACQUISITION  OF  TheraMed  PARTNERS,  INC.  REQUIRES
APPROVAL OF PROPOSALS  ONE THROUGH SIX. IF ALL SIX PROPOSALS ARE NOT APPROVED OR
THE  BOARD OF  DIRECTORS  DETERMINES  NOT TO  PROCEED  WITH THE  ACQUISITION  OF
TheraMed PARTNERS,  INC., THE ACQUISITION OF TheraMed PARTNERS, INC. WILL NOT BE



<PAGE>



CONSUMMATED  AND  THE  BOARD  OF  DIRECTORS,  IN ITS  SOLE  DISCRETION,  HAS THE
AUTHORITY TO NULLIFY STOCKHOLDER APPROVAL OF ANY OF THE PROPOSALS.

         The Board of  Directors  has fixed the close of business on November 8,
1996 as the time as of which  stockholders  entitled to notice of and to vote at
the meeting shall be determined.

                                          By Order of the Board of Directors,


                                          Richard Schubert, Chairman


Bedford, New Hampshire
November __, 1996


     WHETHER OR NOT YOU PLAN TO ATTEND THE  MEETING,  PLEASE  FILL IN,  DATE AND
     RETURN THE PROXY IN THE ENCLOSED POSTAGE-PAID  ENVELOPE. NO POSTAGE NEED BE
     AFFIXED IF THE PROXY IS MAILED IN THE UNITED STATES.


                                       -2-


<PAGE>



                                BIORELEASE CORP.
                                10 Chestnut Drive
                                Bedford, NH 03110

                                 PROXY STATEMENT
                            (Solicited by Management)

                         ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD JANUARY 6, 1997

                                                 Mailing Date: November __, 1996

SOLICITATION OF PROXIES

         This  Proxy  Statement,   together  with  the  accompanying  Proxy,  is
furnished  in  connection  with the  solicitation  of  proxies to be used at the
Annual  Meeting of  Stockholders  of Biorelease  Corp.,  a Delaware  corporation
(hereinafter  called  the  "Company"),  to be held at the  offices of Berry Dunn
McNeil & Parker, 900 Elm Street, 9th Floor, Manchester,  New Hampshire 03101, on
January 6, 1997 at 1:00 in the afternoon.

         A  stockholder  signing and  returning a proxy in the enclosed form has
the power to revoke it at any time before the exercise thereof by giving written
notice to that effect to the  Secretary of the  Company,  by the  submission  of
another  signed  proxy  bearing a later  date or by the  stockholder's  personal
attendance at the meeting and voting by ballot.

         The  solicitation  of proxies in the enclosed form is made on behalf of
the Board of Directors of the Corporation.

         The cost of preparing, assembling and mailing the proxy material and of
reimbursing brokers, nominees and fiduciaries for the out-of-pocket and clerical
expense of transmitting copies of the proxy material to the beneficial owners of
stock held in their names will be borne by the  Company.  The  Company  does not
intend to  solicit  proxies  other  than by the use of the  mails,  but  certain
officers  and  regular  employees  of  the  Company  or its  subsidiary,  for no
additional  remuneration,  may use  their  personal  efforts,  by  telephone  or
otherwise,  to  obtain  proxies.  No firm has been  retained  to  assist  in the
solicitation of broker and nominee proxies.

VOTING SECURITIES OUTSTANDING

         At the close of business  on November 8, 1996,  the record date for the
meeting,  the Company had outstanding  9,471,659 shares of Common Stock, each of
which shares is entitled to one vote.

QUORUM AND VOTE REQUIRED

         The  presence,  in  person or by proxy,  of the  holders  of at least a
majority of the outstanding  shares of Common Stock is necessary to constitute a
quorum at the Annual Meeting.


<PAGE>



Approval of each Proposal will require the affirmative vote of the holders of at
least a majority of the shares of Common Stock of the Company  present in person
or by proxy,  except  for the  election  of  directors,  which is  decided  by a
plurality of the votes  present in person or by proxy and the  amendments to the
Company's Certificate of Incorporation,  which require the affirmative vote of a
majority  of the  issued  and  outstanding  shares.  Management  of the  Company
recommends that you vote your shares in favor of all proposals.

PRINCIPAL STOCKHOLDERS AND STOCK OWNERSHIP OF MANAGEMENT

(a) Security  Ownership of Certain Beneficial Owners -- The persons set forth on
the charts  below are known to the Company to be the  beneficial  owners of more
than 5% of the Company's outstanding voting Common Stock as of the date hereof.

Genesis Farms, Inc (Formerly Genesis Capital,  Inc)., 507 North Belt East, Suite
240,  Houston,  Tx.  77060  has  been  issued  1.5  Million  shares  of Rule 144
restricted Common Stock  representing 15.1% of issued shares. The Company has an
agreement  with a party  claiming  to have an  interest  in 1.4 million of these
shares to recover 1.25 million of these shares of the  Company's  stock  earlier
exchanged  with Genesis in exchange for  advancing  certain  legal costs to this
party and  providing  certain  registered  shares of the Company's  stock.  This
agreement  does not  involve  the  Company  in any  litigation  related  to this
transaction.

(b) Security  Ownership of Management --  Information  concerning the number and
percentage  of shares of voting  Common Stock of the Company owned of record and
beneficially by management, is set forth on the charts below.

Name and                                   Number of Shares        Percent of
Address of                                 Beneficially            Common Stock
Beneficial Owner                           Owned*                  Outstanding**

P. Calvin Maybury                            559,932(1)(2)(4)           5.8%
4102 Cypress Bayou Dr.
Tampa, FL 33624

Richard Schubert                             422,639(1)(4)              4.4%
7811 Old Dominion Dr.
McLean, VA 22102

Richard Whitney                              308,771(1)(3)(4)           3.2%
1612 K  St. N.W. #308
Washington, DC 20006

                                       -2-


<PAGE>




R. Bruce Reeves                              1,799,309(5)               18.9%
10 Chestnut Drive
Unit D
Bedford, NH 03110

All Current Officers and
Directors as a Group
  (3 Persons)                                1,291,342(1)(2)(3)(4)      12.8%


*    Except as indicated in the footnotes below, each person has sole voting and
     dispositive power over the Shares indicated.

**   Based upon 9,471,659 shares issued and outstanding as of the date hereof.

(1)  Includes  179,000  shares  each for Messrs.  Schubert,  Maybury and Whitney
     issuable  upon  the  exercise  of a like  number  of  options  pursuant  to
     consulting agreements with these individuals.

(2)  Includes  140,508  Shares held  individually  by Dr.  Maybury's  wife.  Dr.
     Maybury disclaims  beneficial  ownership of the Shares held individually by
     his wife.

(3)  All  Shares  are  owned  by The  Venture  Fund  of  Washington,  a  limited
     partnership.  Mr. Whitney is a limited partner owning  approximately 19% of
     the limited partnership.

(4)  Includes 30,500; 32,500; and 32,500 options currently exercisable under the
     Company's  Directors'  Stock Option Plan to Messrs.  Maybury,  Schubert and
     Whitney, respectively.

(5)  These 1,799,309 shares, which include 913,200 shares issuable upon exercise
     of options, are held by Robertson, Dr. Reeves' family trust and Dr. Reeves'
     wife. Dr. Reeves'  disclaims  beneficial  ownership in shares held by these
     related parties.

           The table  excludes  shares  issuable upon exercise of 550,000 option
held by Dr.  Paul  Leibowitz,  480,000  of which  have  vested,  for  consulting
services over the past four years.

                       PROPOSAL ONE: ELECTION OF DIRECTORS

           One of the purposes of the meeting is to elect five Directors to hold
office until the next Annual  Meeting of  Stockholders  of the Company and until
their  successors are duly elected and qualified.  The Company's By Laws provide
for a Board of  Directors  consisting  of not less  than one nor more  than nine
members.

                                       -3-


<PAGE>



Nominees

           It is the  intention of the Proxy named in the enclosed form of proxy
to vote all duly executed proxies at this meeting, unless authority is withheld,
for the election of the following five  nominees,  the first two of whom are now
serving as Directors of the Company:  Richard Schubert,  Richard Whitney, Donald
E. Strange,  Nigel Fleming and Paul  Leibowitz.  If, at the time of the meeting,
any of the nominees named is not available to serve as a Director, the Board may
reduce the number of Directors as authorized  under the By-Laws.  The Board does
not anticipate that any nominees will be unavailable to serve, if elected.

           The following  table sets forth certain  information  concerning  the
nominees for Directors:

                                  Company
           Name         Age       Director         Positions with
                                  Since            the Company

Richard Schubert         60       June 1992        Chairman of the
                                                   Board of Directors

Richard Whitney          59       June 1992        Director

Nigel Fleming            42           -            Director

Donald E. Strange        52           -            Director

Paul Leibowitz           55           -            Director

Additional information concerning the nominees for director is as follows:

           RICHARD  SCHUBERT has been  Chairman of the Board of Directors of the
Company since July 1992. Mr. Schubert is currently a business  consultant.  From
December  1990 through  September  1995,  Mr.  Schubert was the President of The
Points of Light  Foundation,  a  foundation  created to  encourage  Americans to
become  directly  involved  in  consequential  community  service  in respect of
critical  social  issues.  From June 1989 to  December  1990,  he was a business
consultant. He served as President of the American Red Cross (1983-1989) and was
a former Vice Chairman and President of Bethlehem Steel until 1982. Mr. Schubert
has extensive experience in law, business and government, and has been appointed
during his career with  Bethlehem  steel,  which began in 1961,  to serve in the
public sector as Assistant to the Under  Secretary of Labor (1970)  Solicitor of
the Department of Labor (1971) and Under Secretary of Labor (1973). Mr. Schubert
is a member of the Council of Foreign Relations and he serves as a director of a
number of philanthropic and business  organizations.  Mr. Schubert graduated Cum
Laude from Eastern Nazarene College in Quincy,  Massachusetts with a Bachelor of
Arts  degree,  and from Yale Law  School  with a  Bachelor  of Law  degree.  Mr.
Schubert,  along  with  Dr.  Reeves,  serves  as an  officer  of NCPI,  Inc.,  a
non-profit subsidiary of Eastern Nazarene College.


                                       -4-


<PAGE>



           RICHARD  WHITNEY has been a Director  of the Company  since July 1992
and Chairman of the Board of Directors of  Biorelease  Technologies,  Inc.  (the
"Subsidiary")  since  August  1996.  He is currently a Principal in a Snelling &
Snelling  franchise  located in Washington D.C. From 1989 until August 1994, Mr.
Whitney  served as a general  partner of The  Venture  Fund of  Washington  (the
"Fund").  The  Fund  has  investors  which  include  pension  funds,   insurance
companies,  banks, and corporations.  It has as a corporate general partner, ICF
International,  a consulting and engineering  firm based in Washington,  DC. Mr.
Whitney  has  managed   venture   funds  since  1972,   beginning   with  direct
responsibility  for the  management  of the Direct  Investment  Fund at Overseas
Private Investment Corporation.  In the mid-1970's,  he served as Executive Vice
President of Narragansett Capital. In 1977, with others, Mr. Whitney purchased a
controlling  interest in Columbia Ventures,  Inc., a SBIC located in Washington,
DC. Mr.  Whitney has served as President  and a Director of that  company  since
1978.  Mr.  Whitney  is a past  director  of the Alumni  Association  and Sports
Foundation of Brown University.

           DONALD E.  STRANGE,  age 52, has been  Chairman  and Chief  Executive
Officer of TheraMed  Partners,  Inc.  ("TheraMed") since its inception in August
1996.  Upon the closing of the  TheraMed  acquisition,  Mr.  Strange will become
Chairman  of the  Board of the  Company.  Since  October  1,  1996,  he has been
Chairman and Chief Executive Officer of First New England Dental Centers,  Inc.,
a provider of dental practice management  services to multi-specialty  practices
in New England.  From 1993 to 1995, Mr. Strange was Chairman and Chief Executive
Officer of Transcare  Corporation,  a patient transport company. Mr. Strange has
over 25 years in the health care field including executive  management positions
with Epic Health Care Group (1991-1993),  US Homecare  Corporation  (1990-1991),
Sigecom Ltd  (1989-1991),  Avon's  Health Care Group  (1987-1989)  and  Hospital
Corporation  of America  (1974-1987).  Mr.  Strange  received a BA from Michigan
State University in 1966 and a MBA from Michigan State University in 1968.

           PAUL LEIBOWITZ,  age 55, a scientific  advisor to the Company for the
past four years, will oversee all pharmaceutical  development and serve as Chief
Operating  Officer and  Director.  Dr.  Leibowitz  has been the Chief  Operating
Officer and Executive Vice  President for  Scientific  Affairs of TheraMed since
its inception in August 1996.  Dr.  Leibowitz  has more than  eighteen  years of
diversified  experience  in the  management  of  biological  and  pharmaceutical
research  and  development,   regulatory  oversight,  business  development  and
strategic planning. From 1994 to 1995, he was a Senior Vice President at Innovir
Laboratories,  Inc., a biotechnology  company.  From 1990 to 1994, Dr. Leibowitz
was Senior Vice  President  of Research  and  Development  and Chief  Scientific
Officer of TSI  Corporation,  a  biotechnology  company  and  contract  research
organization. From 1989 to 1990, he was Vice President of Corporate Planning and
Development for Immunomedics, Inc., a company specializing in radioimmunotherapy
and  radioimmunodiagnostics.  From 1977 to 1987,  Dr.  Leibowitz was employed by
Schering-Plough Corporation, a pharmaceutical company. While at Schering Plough,
Dr. Leibowitz  founded for Schering both the molecular biology and tumor biology
departments and built its initial infrastructure in biotechnology. Dr. Leibowitz
received a BA from New York  University in 1963, a MA from the State  University
of New York at Buffalo in 1970 and a PhD from the State  University  of New York
at Buffalo in 1972.



                                       -5-


<PAGE>



           DR. NIGEL  FLEMING,  age 42, has been an Executive Vice President and
Director  of TheraMed  since its  inception.  Upon the  closing of the  TheraMed
acquisition,  Dr. Fleming will serve as Executive Vice  President,  Strategy and
Business  Development and will assist the Company in its planned acquisition and
business development activities. Since July 1996, Dr. Fleming also has served as
President,  CEO and Director of Plant Cell  Technologies,  Inc., a  biomaterials
company,  and Director of Business  Development for Gamera  Bioscience,  Inc., a
point of care diagnostics company. From 1995 until recently,  Dr. Fleming served
as   Director   of   Business   Development   for   Athena   Neurosciences,    a
neurosciences-based   pharmaceutical   company   that  was   acquired   by  Elan
Pharmaceutical  in June 1996.  In 1986,  he founded  Genica  Pharmaceuticals,  a
neurological  diagnostics  company, and served as its Chairman from 1986 - 1992,
CEO from 1986 - 1989,  Board Member from 1986 - 1995,  Vice  President  Business
Development  from  1992 -  1995  and  Vice  President  until  1995.  Genica  was
ultimately  acquired by Athena  Neurosciences.  Dr.  Fleming is  experienced  in
identifying and  establishing  relevant  diagnostic and  pharmaceutical  product
opportunities. He received a BA with highest honors from the University of North
Carolina  at Chapel Hill in 1978 as a Morehead  Scholar and a faculty  member at
Harvard  medical  school 1985 - 1992 and PhD in Clinical  Biochemistry  from the
University of Cambridge,  England,  in 1983.  From  1985-1992 Dr.  Fleming was a
member of the faculty at the Harvard Medical School.

           Directors  are  elected  to serve  until the next  annual  meeting of
stockholders is until their successors have been elected and qualified. Officers
are appointed to serve until the meeting of the Board of Directors following the
next annual meeting of stockholders and until their successors have been elected
and qualified.

Compliance With Section 16(a) of The Securities Exchange Act of 1934

           To  the  Company's  knowledge,  based  solely  on a  review  of  such
materials as are required by the Securities and Exchange Commission, no officer,
director or beneficial  holder of more than ten percent of the Company's  issued
and outstanding shares of Common Stock failed to timely file with the Securities
and Exchange  Commission any form or report  required to be so filed pursuant to
Section  16(a) of the  Securities  Exchange  Act of 1934  during the fiscal year
ended June 30, 1996.

Executive Compensation

           The  following  table shows all the cash  compensation  paid or to be
paid  by the  Company  or any of its  subsidiaries,  as well  as  certain  other
compensation  paid or accrued,  during the fiscal years indicated,  to the Chief
Executive Officer for such period in all capacities in which he served. No other
Executive  Officer  received total annual salary and bonus in excess of $100,000
during the fiscal years ended June 30, 1996, 1995 and 1994.

                                       -6-


<PAGE>

                           SUMMARY COMPENSATION TABLE
<TABLE>

                                   Annual Compensation                                      Awards                      Payouts

        (a)                (b)               (c)         (d)         (e)            (f)                (g)           (h)         (i)
<S>                      <C>             <C>          <C>           <C>           <C>                 <C>          <C>       <C>

                                                       Other                      ed Stock            LTIP      Compensa-
Name and Principal                                     Bonus       Annual            Award                         tion
Options                                                Payouts     Compen-
Position                 Year              Salary        ($)       sation ($)         ($)             SARs           ($)
  ($)

R. Bruce Reeves,         1996(1)             90,000    -0-           (2)           -0-
Chief Executive          1995                120,000   50,000        (2)           -0-                416,700         -0-        -0-
Officer                  1994                120,000   -0-           (1)           -0-                496,500         -0-        -0-
                         1993                117,000   20,000        (1)           -0-                200,000 (3)     -0-        -0-
                         1992                86,000    10,000        -0-           -0-                   -0-          -0-        -0-
<FN>

          (1)  On April 1, 1996 the direct  employment of R. Bruce Reeves,  then
               President/CEO   of  the  Company   terminated.   All  of  Reeves'
               contractual  rights and  unissued  options  were  assigned to R T
               Robertson Consultants,  Inc., a Reeves family affiliate.  Between
               April 1 and June 30, 1996,  Robertson billed the Company $33,300,
               including expense reimbursements,  for executive oversight of the
               corporations.

          (2)  Value of benefits and other  perquisites are less than 10% of the
               total annual salary and bonus.

          (3)  Effective  October  4,  1996,  these  200,000  options  have been
               forfeited by Dr. Reeves.

</FN>



The following table sets forth  information  with respect to the Chief Executive
Officer concerning the grants of options and Stock  Appreciation  Rights ("SAR")
during the past fiscal year:

<CAPTION>


                      OPTION/SAR GRANTS IN LAST FISCAL YEAR
                                            Individual Grants

    (a)                        (b)                   (c)                    (d)                    (e)
                                                 Options/SARs
                               Options/          Granted to
                               SARs              Employees in          Exercise or Base          Expiration
Name                           Granted           Fiscal Year           Price ($/Sh)               Date
<S>                           <C>                <C>                   <C>                      <C>  

RT Robertson Consultants, I     416,700              100%                  $.06                   12/31/99



                                       -7-
</TABLE>


<PAGE>


The following table sets forth  information  with respect to the Chief Executive
Officer  concerning  exercise  of  options  during  the  last  fiscal  year  and
unexercised options and SARs held as of the end of the fiscal year:

<TABLE>

<CAPTION>


         Aggregated Option/SAR Exercises and Fiscal Year-End Option/SAR
    (a)                         (b)                      (c)                         (d)                       (e)
                                                                                                              Value of
                                                                                  Number of                   Unexercised
                                                                                  Unexercised                 In-the-Money
                                                                                  Options/SARs                Options/SARs
                              Shares                                              at FY-End(#)                at FY-End(#)
                              Acquired on                  Value                  Exercisable/                Exercisable/
Name                          Exercise(#)                Realized($)              Unexercisable               Unexercisable
<S>                           <C>                       <C>                       <C>                        <C>  

R. Bruce Reeves,                -0-                         -0-                     913,2001/0                    -0-
Chief Executive
Officer

<FN>


              (1)    Excludes 200,000 options forfeited as of October 4, 1996.

</FN>

</TABLE>



The following table sets forth  information  with respect to the Chief Executive
Officer concerning awards under long term incentive plans during the last fiscal
year:


<TABLE>

<CAPTION>


                    Estimated Future Payouts under Non-Stock
                                Price-Based Plans
 (a)                       (b)                                (c)                            (d)            (e)              (f)

                                                             Performance
                          Number of                          or Other
                          Shares,Units                       Period Until
                          or Other                           Maturation or                 Threshold        Target       Maximum
Name                      Rights(#)                          Payout                        ($ or #)        ($ or #)     ($ or #)
<S>                      <C>                                <C>                            <C>             <C>          <C>  

R. Bruce Reeves,             -0-                                -0-                          -0-             -0-          -0-
Chief Executive
Officer

</TABLE>



                                       -8-

                                       
<PAGE>


         Directors  are  not   compensated  for  acting  in  their  capacity  as
Directors.  Directors are reimbursed for their accountable  expenses incurred in
attending  meetings and  conducting  their duties.  In April 1995, the Directors
Schubert, Maybury and Whitney were each awarded 129,000 options exercisable into
129,000 shares of common stock at $.08 per share. In September  1995,  Directors
Schubert,  Maybury  and  Whitney  were  awarded  an  additional  50,000  options
exercisable into 50,000 shares of common stock at $.17 per share.  These options
were for  consulting  services  unrelated to their  position as  directors.  The
options expire on December 31, 1999.

         Through March 31, 1996, R. Bruce Reeves,  President and Chief Executive
Officer of the Company, had an employment  agreement with the Company.  Pursuant
to the agreement, Dr. Reeves received an annual salary of $120,000.  Pursuant to
the Agreement,  Dr. Reeves also received  options to purchase  200,000 shares of
the Company (see the "Option/SAR Grants in Last Fiscal Year" table above). These
200,000 option shares were voluntarily  forfeited by Dr. Reeves as of October 4,
1996.  Effective April 1, 1996, due to difficult cash flow problems and in order
to better  assure  payments of benefits  and  compensation  to Dr.  Reeves,  the
Company  entered  into a  consulting  agreement  with  Robertson  to provide the
services of Dr. Reeves to the Company  through the end of the fiscal year ending
June 30,  1996.  Dr.  Reeves  served as President  and CEO of the Company  until
October 4, 1996 when he resigned.  Robertson  continues to actively  consult for
the Company and the  Subsidiary and has agreed to do so for a period of at least
six months  following  the  closing of the  intended  acquisition  of  TheraMed.
Robertson  will  consult for  TheraMed  for three years  following  the intended
acquisition.

         In May 1994, due to the Company's financial condition, in consideration
of a partial salary  deferral and Dr.  Reeves'  continued  involvement  with the
Company,  Dr. Reeves was granted an additional 496,500 options  exercisable at a
price of $.15 per  share  (the  average  per share  market  price on the date of
issue).  These  options,  all of which  were  vested  as of June 30,  1996,  are
currently held by Robertson and expire on December 31, 1999 if not exercised.

Committees and Meetings

         The Company has no Nominating  Committee.  During the fiscal year ended
June 30, 1996,  the Company's  Board of Directors  held two meetings  which were
attended by all of the Directors. The Company has a Compensation Committee which
currently consists of Mr. Whitney and Mr. Schubert.  The principal  functions of
the Compensation Committee are to make recommendations to the Board of Directors
as to compensation arrangements,  and to grant stock options to employees of the
Company. The Compensation Committee met by telephone on two occasions during the
fiscal year ended June 30, 1996 and both members attended these meetings.

     The Company has an Audit Committee which currently  consists of Mr. Whitney
and Mr. Schubert. The Audit Committee met on one occasion relating to the fiscal
year ended June 30, 1996 by telephone with the auditors,  Berry,  Dunn, McNeil &
Parker.


                                       -9-


<PAGE>



Interest of Management and Others in Certain Transactions and Proposals

         In May and July  1994,  the  Company  issued  options  to  purchase  an
aggregate of 1,202,250  shares to current and former officers and consultants in
lieu of cash, including 496,500 options to R. Bruce Reeves.

         On  March  31,  1994,  the  Company   acquired  150,000  shares  of  6%
cumulative,  convertible  preferred  stock of Genesis Farms,  Inc. (then Genesis
Capital  Corporation)  ("Genesis") in consideration for issuing 1,500,000 shares
of the Company's Common Stock to Genesis. On March 31, 1994, the Company's stock
had a fair market value of one dollar per share.  In accordance  with  generally
accepted accounting  principles (the cost method of accounting for nonmarketable
investments),  the Company  recorded the  investment  in Genesis at  $1,500,000.
Management believes the value of Genesis stock has been permanently impaired and
has reduced the basis of the Genesis  preferred stock to $180,000 and $0 at June
30, 1995 and June 30, 1996, respectively. The amount of the permanent impairment
was  determined by reviewing  recent  trading price of Genesis  common stock and
relating  such via the  conversion  rights  of the  Preferred  stock  since  the
underlying  common  stock will be  salable  under Rule 144 within six months (as
required by SFAS No. 115). This value differs  significantly from its historical
cost value. See Note 9 to the Consolidated  Financial  Statements.  On September
16, 1996, the Company entered into an agreement to advance $10,000 in legal fees
to a party  claiming to have an interest in the shares  exchanged by the Company
for the Genesis shares. Under this agreement,  if the Company is successful,  it
will  recover up to 1.25  million of its own shares,  such to be canceled and to
reduce shares outstanding in like amount.  100,000 shares have been recovered as
of the date hereof.

         In May 1994 the Company  borrowed $12,000 from Mr. Shubert for one year
at 9% interest secured by 3,600 shares of Genesis preferred stock. Also, at June
30, 1996, the Company owed Robertson $ 87,734.  Robertson and Mr.  Schubert have
agreed to defer  payment of these  amounts due for a period of up to three years
from the  closing of the  TheraMed  acquisition  without  interest.  Anytime the
Company reaches $2 million in working  capital,  these amounts shall become due.
Mr. Schubert has released any interest he holds in the Genesis shares.

         In June 1996,  the Company  issued  509,396  shares of its Common Stock
(inclusive of 41,305 shares that were issued  effective July 1996) in settlement
of $29,366 in 1996 and $251,134 in 1995 of the  Company's  and the  Subsidiary's
liabilities.

     Dr. R.  Bruce  Reeves,  the  former  President,  Chief  Executive  Officer,
Secretary  and Director of the Company,  who  resigned  from these  positions on
October 4, 1996, is an employee of Robertson.  Dr.  Reeves,  through  Robertson,
continues  to be  involved  in the daily  business  of the  Company  and will be
actively involved in the business of the Company and TheraMed after the TheraMed
acquisition.  In addition,  following  consummation of the TheraMed acquisition,
Robertson,  currently a principal stockholder of the Company, has entered into a
consulting  contract  with  TheraMed for a period of three years (see  "Proposal
Three:  Acquisition Of TheraMed  Partners,  Inc." below) and will own options to
purchase  approximately  1,155,000  post reverse split shares of Company  Common
Stock, which options vest over a two year period.  These options are in addition
to other options  currently held by Robertson.  See "Principal  Stockholders And
Stock  Ownership  Of  Management"  above and  "Proposal  Three:  Acquisition  Of
TheraMed Partners, Inc." below.

                                      -10-


                                   
<PAGE>

         Robertson  presently holds a substantial  number of Company options and
will  receive a  substantial  number of  options  (see the prior  paragraph  and
"Principal  Stockholders And Stock Ownership of  Management").  Dr. Reeves has a
vested interest in seeing that the TheraMed acquisition is approved.  Similarly,
Paul  Leibowitz,  a consultant to the Company who owns a  significant  number of
Company options (see "Principal  Stockholders And Stock Ownership of Management"
above) and  TheraMed  shares and will be a Principal  Stockholder,  an executive
officer and a Director of the Company after the TheraMed acquisition, and Donald
E. Strange and Nigel Fleming,  nominees for director of the Company who each own
significant  number  of  TheraMed  shares  and will be  Principal  Stockholders,
Executive  Officers  and/or  Directors  of the Company  following  the  TheraMed
acquisitions,  have a vested interest in seeing that the TheraMed acquisition is
approved.

         For additional information concerning current management of the Company
see  "Management"  in the Company's 1996 Annual Report  accompanying  this Proxy
Statement.


         PROPOSAL TWO: AMENDMENT OF THE CERTIFICATE OF INCORPORATION TO
         AUTHORIZE PREFERRED STOCK

         Stockholders  are hereby  requested to consider and act upon a proposal
to amend the Company's  Certificate  of  Incorporation  to authorize  10,000,000
shares of Preferred  Stock,  $.01 par value.  As amended,  Article FOURTH of the
Company's   Certificate  of  Incorporation,   which  sets  forth  the  Company's
authorized number of shares would read as follows:

     "FOURTH. (a) The Company is authorized to issue 50,000,000 shares of Common
Stock,  with a par value of $.01 per share,  and 10,000,000  shares of Preferred
Stock, with a par value of $.01 per share.

         (b) The  Board  of  Directors  of the  Company  shall be  empowered  to
designate the rights,  powers,  preferences  and  designations  of the Preferred
Stock  described above with regard to any shares of Preferred Stock that are not
issued and outstanding."

         The Company has not made any decision respecting the issuance of shares
of Preferred  Stock.  However,  management  deems it wise to authorize shares of
Preferred  Stock at this time,  because,  in its opinion,  it is important  that
management  have available to it the means and  flexibility to take advantage of
any opportunities that may occur without incurring the expense or delay involved
with holding a special meeting of stockholders to authorize shares.  Some or all
of such shares would be available  for sale to raise  additional  equity for the
Company  or for  issuance  in the event  the  Company  acquired  a  business  or
technology for consideration  which was payable in whole or in part in shares of
the Company's  Stock.  The foregoing is consistent with the TheraMed's  business
plan (see "Proposal Three: Acquisition Of TheraMed Partners, Inc." below).

                                      -11-


<PAGE>

         Stockholders should note that the Company's Board of Directors would be
empowered to designate the rights,  powers,  preferences and designations of the
Preferred  Stock  (including,  but not limited to,  preferences on dividends and
liquidation  and  conversion  and/or  redemption  rights)  without   Stockholder
approval  and that  the  Board of  Directors  does not plan to seek  stockholder
approval for the issuance of such shares unless required by law.

         The Board of Directors  could issue shares of Preferred Stock with such
rights  and  preferences  that  could  discourage  attempts  by others to obtain
control of the Company through merger,  tender offer, proxy contest or otherwise
by making such attempts more difficult to achieve or more costly.

         Stockholders are referred to the Company's audited financial statements
as of and for the fiscal year ended June 30,  1996  contained  in the  Company's
Annual Report, which Report accompanies this Proxy Statement.

Board Recommendation

         The Board of Directors  believes  that the  authorization  of Preferred
Stock is in the best interest of the Company  because it will assist the Company
in effectuating TheraMed's planned business operations.  Accordingly,  the Board
of Directors recommends a vote FOR this proposal.


         PROPOSAL THREE:  ACQUISITION OF TheraMed PARTNERS, INC.

         One of the purposes of the meeting is to approve the acquisition of the
Common Stock of TheraMed  Partners,  Inc.  ("TheraMed").  In November  1996, the
Company entered into an "Agreement and Plan of Reorganization  (the "Agreement")
to acquire  (the  "Acquisition")  all of the issued  and  outstanding  shares of
Common Stock of TheraMed,  a recently formed Delaware  corporation that plans to
focus on acquiring  and  consolidating  late stage  biotechnology  companies and
pharmaceutical synergistic technologies,  in exchange for 4,125,000 post reverse
split shares of the Company's  Common Stock. A copy of the Agreement is attached
hereto as Attachment A. As part of the transaction, options to purchase TheraMed
Common  Stock held by R T Robertson  Consultants,  Inc.  will be  exchanged  for
Company  options to purchase an aggregate of 1,155,000 post reverse split shares
of the  Company's  Common  Stock.  These  options  vest  over a two year  period
following closing of the TheraMed  acquisition.  When taken together with shares
held by existing management and directors of the Company, TheraMed stockholders,
Robertson and the Company's existing management and directors together will hold
a controlling  interest in the Company.  Immediately  following the acquisition,
the Company will have approximately 6,565,415 (post reverse split) shares issued
and  outstanding  in addition to  approximately  2,844,388  (post reverse split)
shares issuable upon exercise of options.


                                      -12-


<PAGE>

         Pursuant to the  Agreement,  consummation  of the TheraMed  acquisition
requires  stockholder   approval  of  the  following:   (i)  a  name  change  to
"Pharmatrage  Holdings,  Inc."  (Proposal  Four);  (ii) a  reverse  split of the
Company's issued and outstanding  shares of Common Stock on a one-for-four basis
(Proposal Five);  (iii) the  authorization of preferred stock, the designations,
rights,  preferences  of  which  may  be  determined  at the  discretion  of the
Company's  Board of Directors  (Proposal  Two);  (iv) the election of a slate of
directors  which will  include  existing  directors  Schubert  and Whitney  plus
TheraMed  directors Donald E. Strange Paul Leibowitz and Nigel Fleming (Proposal
One); and (v) the spin off of all  Subsidiary  shares held by the Company to the
Company's (pre TheraMed  acquisition)  stockholders  (Proposal Six) and (vi) The
approval of the T Ac (Pro three).

         As a result of the acquisition of TheraMed and upon the effectuation of
the  one-for-four  reverse split and the spin off of the Subsidiary,  in lieu of
every four shares of Company stock held by stockholders  before  consummation of
these  transactions,  a stockholder  will own one share of the Company's  common
stock and three shares of the Subsidiary's common stock.

         CONSUMMATION  OF THE  ACQUISITION  OF  TheraMed  REQUIRES  APPROVAL  OF
PROPOSALS ONE THROUGH SIX. IF ALL SIX PROPOSALS ARE NOT APPROVED OR THE BOARD OF
DIRECTORS  DETERMINES  NOT TO PROCEED  WITH THE  ACQUISITION  OF  TheraMed,  THE
ACQUISITION OF TheraMed WILL NOT BE CONSUMMATED  AND THE BOARD OF DIRECTORS,  IN
ITS SOLE DISCRETION, HAS THE AUTHORITY TO NULLIFY STOCKHOLDER APPROVAL OF ANY OF
THE PROPOSALS.

         TheraMed,  primarily through Robertson, is overseeing the operations of
the Company prior to closing at the direction of the current Board of Directors.
TheraMed has also agreed to advance  operating  funds to the Company to allow it
to continue operations pending stockholder approval of the transaction.

         As a  condition  of the  proposed  TheraMed  transaction,  Dr.  Reeves,
resigned as the Company's  President,  Chief  Executive  Officer,  Secretary and
Director  on October 4, 1996.  Dr.  Reeves is employed  by  Robertson  which has
entered  into a  consulting  agreement  with  TheraMed  for at least three years
following  the closing of the TheraMed  acquisition.  Compensation  to Robertson
will include TheraMed stock options, which upon the consummation of the TheraMed
acquisition,  will be converted into options to purchase approximately 1,155,000
reverse split shares of the Company's  Common Stock.  Robertson  will consult in
the areas of capital formation, securities law compliance, stockholder relations
and financial matters.  Limited additional staff and outside consultants will be
added to assist in the development and technology acquisition efforts as needed.
For more  information  concerning  Dr.  Reeves and  Robertson  see  "Interest of
Management  and Others in Certain  Transactions  and  Proposals"  and "Principal
Stockholders And Stock Ownership Of Management."

         Pursuant to the Agreement,  the Company will grant the current TheraMed
stockholders "piggy back" registration" rights with regard to the Company shares
to be issued to them in exchange for their TheraMed shares.  Commencing one year


                                      -13-


<PAGE>



after the closing of the TheraMed transaction,  these holders will have the
right to have their Company shares  registered by inclusion in any  registration
statement that the Company may file, except for registration statements on Forms
S-4 and  S-8.  In  addition,  following  the  closing,  in  accordance  with the
performance schedule described below, the Company will issue options to purchase
an aggregate of 782,052 post reverse  split shares at an exercise  price of $.34
per  share  for a  period  of ten  years  after  issuance  to Mr.  Strange,  Dr.
Leibowitz,  Dr. Fleming and  Robertson.  One fourth will vest upon the Company's
securities  becoming listed on AMEX or NASDAQ within 18 months of the closing of
the  TheraMed  transaction;  one fourth will vest upon the  Company  obtaining a
working  capital  level of  $500,000  within  nine  months of the closing of the
TheraMed  transaction;  one  fourth  will vest upon the  Company  completing  an
acquisition with a target company having a market value of $5,000,000  within 12
months of the closing of the TheraMed transaction; and one fourth will vest upon
the  Company  obtaining  a  market  capitalization  for 30  consecutive  days of
$15,000,000 within 24 months of the closing of the TheraMed  transaction.  Up to
195,513 options in the Company will be granted to unrelated consultants,  75,000
of which have been  issued to two  pharmaceutical  consultants;  the  balance of
120,513  options  have not been  issued,  and will not be issued to any TheraMed
principal.

TheraMed Partners, Inc.

         TheraMed's  executive office is currently  located at the offices of RT
Robertson  Consulting,  10 Chestnut  Drive,  Bedford New Hampshire 03110 and its
telephone number is (800 408-0089.)

         Following the Acquisition,  the Company,  through  TheraMed,  will be a
product and technology acquisition company and development entity with a primary
focus  on  developing  later  stage  products  acquired  out of the  anticipated
consolidation of the  biotechnology  and  pharmaceutical  industry over the next
several years. Management intends to use as its primary selection criteria those
proprietary  technologies  and products for which  preclinical and clinical data
exist that supports potential commercial viability and success.

         One  area in  which  the  Company  expects  to  initially  focus  is on
acquiring proprietary drug delivery technology that could be useful in providing
normal  dosage  forms that would  enable it to enter new  markets or improve the
safety or efficiency profile of existing drugs.

         It is  anticipated  that the Company  will seek out  affiliation  with,
and/or   acquisition  of,  companies   unable  to  independently   continue  the
development  of their  products  who will  benefit  from the  experience  of the
Company's new management and support.

     Mr.  Donald E.  Strange,  Dr. Paul  Leibowitz and Dr. Nigel Fleming are the
founders, current principal stockholders and Executive Officers and/or Directors
of TheraMed.  Upon  consummation of the TheraMed  acquisition,  Mr. Strange will
become the Company's  Chairman.  Dr.  Leibowitz will become the Company's  Chief
Operating  Officer and a Director and Dr. Fleming will become its Executive Vice
President,  Strategy and Business  Development and a Director of the Company and
will assist the Company in acquisition and business development activities.  For
information  on Mr.  Strange,  Dr.  Leibowitz and Dr. Fleming see "Proposal One:
Election Of Directors."

                                      -14-


<PAGE>

Accounting Treatment

     Biorelease  Corp.  intends to treat the Merger as a purchase for accounting
purposes.

     The pro forma financial  information  presented in this Proxy Statement has
been prepared using the purchase method of accounting to account for the Merger.
See "UNAUDITED PRO FORMA COMBINED FINANCIAL DATA."

Pro forma financial information

         The following  unaudited pro forma financial  information as of and for
the quarter ended September 30, 1996 is being presented for Biorelease Corp. its
subsidiary Biorelease Technologies, Inc. (the Subsidiary) and TheraMed Partners,
Inc. (TheraMed).  The presentation as of and for the period ending September 30,
1996,  the first quarter of  Biorelease,  is to show the effects of the proposed
merger with  TheraMed and spinoff of the  Subsidiary.  A pro forma  statement of
operations for the most recent fiscal year is not being presented  because it is
not deemed necessary since TheraMed was formed subsequent to June 30, 1996.

         The pro forma information presents the activity of Biorelease Corp. and
TheraMed as if the merger had occurred as of and for the period ended  September
30, 1996. All intercompany  activity has been  eliminated.  The activity for the
Subsidiary has been  eliminated in its entirety  because the terms of the merger
require this company to be "spun out" to the holders of Biorelease  Corp.  prior
to the TheraMed acquisition.  The acquisition of TheraMed is to be accounted for
using the purchase method of accounting and the cost of the acquisition is to be
based on the net asset value of TheraMed at the time of closing. As of September
30, 1996,  TheraMed did not have a positive net asset value.  Management assumes
TheraMed will have negligible net asset value at closing.

         This pro  forma  information  should  be read in  conjunction  with the
related historical  information and is not necessarily indicative of the results
that would have been attained had the transaction actually taken place.


                                      -15-



<PAGE>

<TABLE>


<CAPTION>


                BIORELEASE CORP
                (A DEVELOPMENT STAGE ENTERPIRSE)
                PROFORMA BALANCE SHEET
                SEPTEMBER 30, 1996
                (Unaudited)                                         Elimination     Proforma        Proforma        Proforma
        ASSETS                                   BCORP  BTI  TPI    Adjustments     Adjustments     A/E #   Results
<S>                                            <C>      <C>  <C>    <C>            <C>            <C>


Cash .........................................   156     0 23589           0   
Cash - held as collateral ....................     0     0     0
Investments in government securities .........     0     0     0
Investments in government backed securities ..     0     0     0
Accounts receivable, trade ...................     0   192     0                        (192)     5                            5
Accounts receivable-affiliate ...............3668534     0  5000   (3668534)                    1,2     
Inventories ..................................     0 27679     0                    (27679)       5
Deferred income taxes ........................     0     0     0          0
Other receivables ............................  1015     0     0          0
Prepaid expenses and other current assets ....  2311     0     0          0  
                                                       ---   ---   --------     -------------   ---   --------
     Total current assets ................   3672016 27871 28589   (3673534)         (27871)
Equipment and leasehold improvements, net ....                                         27044     0          0
Investments, net .............................              4582          0                0   -4582        8
Investments in subsidiaries ..................     0     0     0   3,6
Intangible assets, net .......................     0       36110          0   -36110            5          5
Other noncurrent assets ......................   398   300     0                          0   -300         5
Deferred underwriting fees for future offering     0     0                                             12500
Deferred legal fees for future acquisition ...                                        14811     0          0
                                                       ---   ---   --------   -------------   ---   --------
     Total assets ............................                                3718851 36410   -37373      18
                                                       ===   ===   ========   =============   ===   ========
        LIABILITIES AND STOCKHOLDERS' EQUITY
Accounts payable ............................. 28993 65453  3215          0   -65453            5      32213
Accounts payable - affiliate .................  5000   366853-5000 -3668534   1,4              14   off 1748
Accrued expenses ............................. 70779 25841   375          0   -25841            5      71159
Notes payable - stockholders .................     0       55600      80000   -55600            5      80005
Income taxes payable .........................     0                   1549               0   -1549        5
Deferred income taxes ........................     0     0     0                                           0
Other current liabilities ....................              1748       4000               0   -4000        5
                                                       ---   ---   --------   -------------   ---   --------
     Total current liabilities ...............                       106520   3820977 83590   -3820977183391
Notes payable - long term:
  Stockholders ...............................                        14955           11975   -11975       5
  Others .....................................     0       16000          0               0   -16000       5
Other liabilities ............................                                        87734     0      87734
                                                       ---   ---   --------   -------------   ---   --------
     Total liabilities .......................                       209209   3848952 83590   -3848952271125
                                                       ---   ---   --------   -------------   ---   --------
Stockholders' equity:

     Common stock of $.01 par value, 50,000,000 shares authorized 9,880,354
       and  13,512,263  shares  issued and  9,430,354  and  8,962,263  shares
       outstanding at June 30, 1996 and

     Common stock                       99217   5047    1       -1      -34835  2,5,7,8,9       95218   June 30, 1995, respectively
     Additional paid-in capital                 6989159 2129673 0       1       -2099885        2,3,4,5,7,8,9   9364737    -5798207
     Development stage accumulated deficit      -3524234    -5919391   -42501  2246275 5,6,8   -7239283  corp -2 3696405
     Stock subscriptions receivable                     -50000  0       -1                              -50001                65453
                        -       -       -       -       -               -                       -
                        3514142 -3784671        -42501          111555          2170671                 -2036349
     Less:   Treasury stock                     -4500   0       0
                        -       -       -       -       -               -
     Total stockholders' equity                 3509642 -3784671        -42501          111555          2170671
                        -       -       -       -       -               -
     Total liabilities and stockholders' equity                 3718851 64281   41089           -3737397                2441796
                        =       =       =       =       =               =


<CAPTION>

                                  BIORELEASE CORP
                      (A DEVELOPMENT STAGE ENTERPRISE)
                PROFORMA  CONSOLIDATING  STATEMENT OF  OPERATIONS  For the Three
                 Months Ended September 30, 1996

                                         (Unaudited)



                               3 MONTHS SEPT 1996                       Elimination     Proforma        Proforma
                        BCORP   BTI     TPI     Adjustments     Adjustments     Results
<S>                    <C>       <C>       <C>         <C>                <C>                <C>
  
Revenues .......................................     0                  12691                 0

Cost of Goods Sold .............................     0     0     0
- ------------------------------------------------   ---   ---   ---   --------   ---------------
Gross Profit

Operating expenses:
   General and administrative ..................         -34405-9912 -42501     -86818

- ------------------------------------------------   ---   ---   ---   --------   ---------------
Loss from operations ...........................               -34405-42501     -86818

Other income (costs) :
   Interest, net ...............................     0               -981                     0
   Loss on disposition of invest-
     ment in subsidiaries ......................     0     0     0   -3671958   -3671958
- ------------------------------------------------   ---   ---   ---   --------   ---------------
- ------------------------------------------------   ---   ---   ---   --------   ---------------
NET LOSS .......................................         -34405-42501-3671958   -3758776
================================================   ===   ===   ===   ========   ===============
Weighted average shares ........................                                        5117915
Loss per share .................................                                -0.734435018948


REMOVE BELOW DETAIL BEFORE CREATING DISC FOR SEC


shares outstanding at 6/30/96 ..................           9430354          0           2357589
July ...........................................             41305          0             10326
August .........................................     0   750                            4125000
September ......................................     0     0     0
                                                               ---   --------   ---------------
total 9-30-96 ..................................                      9471659           6492915
                                                               ===   ========   ===============





                                 BIORELEASE CORP
             CONSOLIDATED ELIMINATION AND PROFORMA ADJUSTING ENTRIES
                               DECEMBER 31, 1994        SEPTEMBER 30, 1996




        ELIMINATION ADJUSTMENTS


 1      ELIMINATE INTERCOMPANY RECEIVABLE/ PAYABLE IN CONSOLIDATION

        ACCOUNTS PAYABLE- AFFILIATE - BCORP                            5000
                ACCOUNTS RECEIVABLE - AFFILIATE - TPI                  5000

 2      ELIMINATE INVESTMENT IN SUBSIDIARIES

        COMMON STOCK - TPI                                              1
                APIC - BCORP                                            1



                                                        -       -

                                                        =       =
        PROFORMA ADJUSTMENTS

 3      TO RECLASSIFY BTI'S LIABILITY TO BCORP AS ADDITIONAL PAID IN CAPITAL

        ACCOUNTS PAYABLE- AFFILIATE - BTI                              3668534
                ADDITIONAL PAID IN CAPITAL - BTI                       3668534

 4     TO RECLASSIFY  BCORP'S RECEIVABLE FROM BTI TO INVESTMENTS IN SUBSIDIARIES

        INVESTMENT IN SUBSIDIARIES - CORP                              3668534
                ACCOUNTS RECEIVABLE - AFFILIATE - B CORP               3668534


5       SPIN OUT BTI FROM CONSOLIDATED PROFORMA RESULTS

        ACCOUNTS PAYABLE- BTI                                           65453
        ACCRUED EXPENSES - BTI                                          25841
        NOTES PAYABLE STOCKHOLDERS -BTI                                 58100
        INCOME TAXES PAYABLE - BTI                                       1549
        OTHER CURRENT LIABILITIES - BTI                                  4000
        NOTES PAYABLE - STOCKHOLDERS - BTI                              25475
        COMMON STOCK - BTI                                              5047
        ADDITIONAL PAID IN CAPITAL - BTI                              5798207
        DEVELOPMENT STAGE ACCUMULATED DEFICIT -BTI                   5919391
                ACCOUNTS RECEIVABLE - BTI                                192
                INVENTORIES - BTI                                    27679
                INTANGIBLE ASSETS - BTI                              36110
                OTHER NONCURRENT ASSETS - BTI                        300




 6      TO WRITE-OFF BCORP'S  RECEIVABLE IN SUBSIDIARY BTI

        LOSS ON DISPOSITION OF INVESTMENT IN SUBSIDIARY - BCORP       3668534
                INVESTMENTS IN SUBSIDIARIES - B CORP                  3668534

 7      PROFORMA ISSUANCE OF 1,650,000 BCORP STOCK TO SHAREHOLDERS OF TPI
        (BASED ON TPI RECEIVING 4 SHARES OF BIO FOR EACH SHARE OF TPI)
         (750BTI + 750 NEW BTI =1500sh x 2750 x4)
        ADDITIONAL PAID IN CAPITAL - BCORP                          165000
                COMMON STOCK - BCORP                                 165000

 8      WRITE OFF BCORP'S INVESTMENT IN BTI

        LOSS ON DISPOSITION OF INVESTMENT IN SUBSIDIARY -BCORP          4582
                INVESTMENTS, NET - BCORP                                4582


 9      REFLECT THE REVERSE SPLIT OF BCORP STOCK ON A ONE FOR  FOUR BASIS

        COMMON STOCK - BCORP                                            194788
                ADDITIONAL PAID IN CAPITAL - BCORP                    194788
                        ISSUED BCORP SHARES                     99217
                        LESS TREASURY STOCK                     -4500
                        BCORP SHARES ISSUED TO BTI                      165000
                                                -
                TOTAL PROFORMA SHARES                           259717
                SPLIT TO EQUAL                          64929
                                                -
                ADJUST                          194788
                                                =       -       -
                                                        10016576        10016576
                                                        =       =

                                                               -16-
</TABLE>


<PAGE>

Material Federal Income Tax Consequences

         The  following  summary  sets forth the  anticipated  material  federal
income tax consequences of the transactions  outlined in this proxy.  Biorelease
Corp.  (the  Company  has not  obtained  an  opinion  of  counsel  and  does not
contemplate  obtaining  such an  opinion.)  It is  management's  belief that the
following  discussion  covers the potential  impact to the Company  shareholders
from the spin-off of the Subsidiary  and the subsequent  exchange of the Company
voting stock solely for voting stock of TheraMed  Partners,  Inc.(TPI).  The tax
treatment  of each  the  Company  shareholder  will  depend  in part  upon  such
shareholder's particular situation. Special tax consequences not described below
may  be  applicable  to  particular  classes  of  taxpayers  including,  without
limitation,   foreign   corporations  and  tax-exempt   entities.   The  Company
shareholders should consult their own tax advisors as to the effect of their own
particular  situation on the federal tax  consequences of the proposed  spin-off
and subsequent  exchange of stock,  as well as the  applicability  of any state,
local or other tax laws. This summary is based on the provisions of the Internal
Revenue Code (IRC), as in effect as of the date hereof.  Such laws,  regulations
or  interpretations  may differ upon the effective date of this  transaction and
relevant facts also may differ.

         Spin-off of BTI to the current shareholders of the Company.  Management
believes  that the spin-off of the BTI  subsidiary  to the  shareholders  of the
Company will constitute a taxable distribution under Section 301 of the Internal
Revenue Code. The receipt of BTI stock in a taxable  spin-off would generally be
taxable as a dividend to the extent of the fair  market  value of the BTI common
stock received by the Company shareholders. The dividend treatment is limited to
the  accumulated  earnings  and  profits  of  the  Company.  It is  management's
contention that the Company has no accumulated earnings and profits,  therefore,
the  distribution  will be treated as a sale or exchange of  property.  As such,
management  believes that part of the  distribution  will be a return of capital
with the balance taxable as the capital gain, The amount of taxable capital gain
versus return of capital has not been  determined at this time, and would likely
vary from shareholder to shareholder.

         In a taxable spin-off,  the Company is required to recognize gain equal
to the amount by which the fair market value of the BTI stock distributed to the
Company shareholders exceeds the Company's basis in that BTI stock. No loss will
be recognized  for tax purposes if the Company's  basis in the BTI stock exceeds
the fair market  value of the BTI stock  distributed.  It is  expected  that the
spin-off of BTI will result in a loss to the Company.  In the past, the Company,
together with its subsidiary BTI, filed consolidated federal income tax returns.
Therefore,  the spin-off of BTI may result in the  triggering of any excess loss
accounts  or  deferred  intercompany  transactions,  which may result in taxable
income to the  Company.  Management  believes  that this is highly  unlikely  to
occur,  and has not determined the existence or amount of any such excess losses
or deferred intercompany transactions.

         It is not  anticipated  that BTI will have any direct tax  consequences
from the Company spinning off its stock to the current the Company shareholders.
BTI does have a  substantial  net  operating  loss  which may be  limited if the
spin-off to the Company  shareholders  is  considered  a change in  ownership as
defined in IRC Section 382(g).  If it is determined that an ownership change has
occurred,  then the opportunity to use the company's net operating losses in the
future will be substantially limited under IRC Section 382.

                                      -19-


<PAGE>


         Exchange of the Company voting stock solely for voting stock of TPI. It
is management's  intention that the exchange of the Company voting stock for all
the outstanding voting stock of TPI qualifies under IRC Section  368(a)(1)(B) as
a  tax-free  exchange  ("B"  reorganization).  If  the  requirements,  of a  "B"
reorganization  are not met, then the  transaction  will be considered a taxable
sale or exchange. The company does not anticipate any direct tax consequences to
the existing the Company shareholders under either scenario.

         It is not  anticipated  that  the  Company  will  have any  direct  tax
consequences  from  exchanging its stock for the stock of TPI if the transaction
qualifies as a "B" reorganization under IRC Section 368(a)(1)(B) of the IRC. The
Company does have a substantial  net operating  loss which may bc limited if the
exchange with TPI shareholders is considered a change in ownership as defined in
IRC Section 382(g).  If it is determined  that an ownership  change has occurred
then the  availability  to use the company's net operating  losses in the future
will be substantially  limited. It is anticipated that the exchange will trigger
the net operating loss limitation under IRC Section 382.

Plans for the Combined Companies

         The Company is currently offering up to $500,000 in notes to accredited
parties  to  provide  initial  working  capital  for the  implementation  of the
Pharmatrage/TheraMed  acquisition and initial merger and acquisition activities.
Assuming the approval of the TheraMed transaction by the Company's stockholders,
expected by early  January,  1997,  the Company,  under the name of  Pharmatrage
Holdings,  Inc. will undertake to complete a private placement on a best efforts
basis.  A New York City  investment  banking  company has been engaged to manage
this financing for the Company. During the first two quarters following approval
of the TheraMed  transaction and assuming completion of a significant portion of
the private placement,  the Company intends to complete its first acquisition of
a targeted "Core Technology Company" through which it plans to consolidate other
technologies and product  opportunities.  No specific "Core Technology  Company"
has been selected by the Company as the first  acquisition.  The Company expects
to remain virtual in its  organization for the first year while it evaluates the
benefits of integration between Company activities and the first core technology
company.  Based on both new acquisition  opportunities and the Company's ability
to attract  new  working  capital,  the  Company  will  regularly  evaluate  the
potential for adding new technology to its first core technology company.

Description of Common Stock

         The Company is authorized to issue fifty million (50,000,000) Shares of
Common Stock, $.01 par value per Share, of which 9,471,659 Shares are issued and
outstanding.  Each  outstanding  Share of Common  Stock is entitled to one vote,
either  in  person or by proxy,  on all  matters  that may be voted  upon by the
owners thereof at meetings of the stockholders.

         

                                      -20-


<PAGE>



     The holders of Common Stock (i) have equal ratable rights to dividends from
funds  legally  available  therefor,  when,  and if  declared  by the  Board  of
Directors  of the  Company;  (ii) are  entitled  to Share  ratably in all of the
assets of the Company available for distribution to holders of Common Stock upon
liquidation,  dissolution or winding up of the affairs of the Company;  (iii) do
not have preemptive, subscription or conversion rights, or redemption or sinking
fund provisions  applicable thereto; and (iv) are entitled to one non-cumulative
vote per Share on all matters on which  stockholders may vote at all meetings of
stockholders.

         For market  information  concerning  the Company's  Common  Stock,  see
"Market For The Company's Common Equity And Related Stockholder  Matters" in the
Company's 1996 Annual Report that accompanies this Proxy Statement.

Board Recommendation

         The Board of Directors  believes that the acquisition of TheraMed is in
the best interest of the Company and its stockholders because under the TheraMed
agreement  the present  holders  continue on an undiluted  basis to benefit from
their holdings in the subsidiary's  existing  business  opportunity  through new
stock  issued to them in the  subsidiary,  while  retaining  a 37%  prefinancing
interest in the new Pharmatrage/TheraMed business opportunity. Further, TheraMed
has and will  continue to advance  funds to and for the benefit of the  Company.
Management of TheraMed can be expected to materially  enhance the ability of the
Company to both identify new  biotechnology  opportunities  and attract capital.
Accordingly, the Board of Directors recommends a vote FOR this proposal.

         PROPOSAL FOUR: AMENDMENT OF THE CERTIFICATE OF INCORPORATION
         TO CHANGE THE COMPANY'S NAME TO "PHARMATRAGE HOLDINGS, INC."

         One of the requirements  for  consummating the TheraMed  acquisition is
that the Company changes its name to "Pharmatrage Holdings, Inc."

Board Recommendation

         The Board of  Directors  of the  Company  and  management  of  TheraMed
believe that the new name is more appropriate in light of the shift in direction
of the  Company's  business.  As noted above,  the name change is a condition to
effectuation of the TheraMed  acquisition.  For the foregoing reasons, the Board
of Directors recommends a vote FOR this proposal.

         PROPOSAL FIVE: REVERSE SPLIT OF THE COMPANY'S ISSUED AND
         OUTSTANDING SHARES OF COMMON STOCK ON A ONE-FOR-FOUR BASIS

         One of the requirements  for  consummating the TheraMed  acquisition is
that all issued and outstanding  shares of the Company's Common Stock be reverse
split  on a  one-for-four  basis  with any  resulting  fractional  shares  being
increased to the next whole share.

         As a result of the one-for-four reverse split,  following  consummation
of the TheraMed  acquisition,  there will be 6,565,415 post reverse split shares
of the  Company's  Common Stock issued and  outstanding  consisting of 4,125,000
post reverse split shares issued to the  stockholders  of TheraMed and 2,440,415
post reverse split shares held by the pre-acquisition Company stockholders.

                                      -21-


<PAGE>

         As a result of the reverse split, the terms of all outstanding  options
and  warrants  for the  Company's  Common Stock will be adjusted by reducing the
number of shares issuable upon exercise of such options and warrants by a fourth
and adjusting  the exercise  price of such options and warrants in proportion to
the reverse split and to reflect the allocation of valuation  resulting from the
spin off of the  Subsidiary  and the  decrease  in the  number  of shares in the
Company after the split back.

Board Recommendation

         The Board of  Directors  of the  Company  and  management  of  TheraMed
believe  that the  reverse  split is  necessary  to allow  the  expected  market
capitalization  following the proposed private placement described earlier,  and
possibly  after its first  acquisition,  to result in a stock  price which would
give the  Company the  opportunity  to become  eligible  for a listing on either
NASDAQ or the American Stock  Exchange.  Without  splitting  back, the directors
feel the stock would possibly  continue to be classified as a penny stock,  even
after significantly increasing the Company's market capitalization,  which would
impede the  possibility  of wider  coverage and investor  eligibility.  As noted
above,  the  reverse  split  is a  condition  to  effectuation  of the  TheraMed
acquisition. For the foregoing reasons, the Board of Directors recommends a vote
FOR this proposal.

             PROPOSAL SIX: SPIN OFF OF BIORELEASE TECHNOLOGIES, INC.

         One of the requirements  for  consummating the TheraMed  acquisition is
that the Company  divest itself of its current  business  operations.  Since all
investments  to date in the Company have been in  furtherance of the business of
the Company's Subsidiary,  the Company, with stockholder approval, plans to spin
off all  Subsidiary  shares held by the Company to the Company's  (pre- TheraMed
acquisition)  stockholders.  The Company will adjust the  capitalization  of the
Subsidiary  by  forward  or reverse  stock  split to assure  that for every four
shares  of the  Company  owned by  eligible  Company  stockholders  prior to the
acquisition of TheraMed,  the reverse split and the spin off of the  Subsidiary,
such stockholder,  upon consummation of all of the foregoing transactions,  will
receive three shares of the  Subsidiary and one split back share in the Company.
It is anticipated that the record date for the transaction will be the day prior
to the date of consummation of the TheraMed acquisition.

         The spin off transaction must be registered under the Securities Act of
1933 and must be registered  or exempt from  registration  under the  applicable
State securities laws.

         As a condition to the spin off, it is  anticipated  that the Subsidiary
will grant the Company an  exclusive  license,  subject to the  existing  rights
licensed to Baiter Healthcare  ("Baiter"),  to use the Subsidiary's  Chondroitin
Sulfate  Technology  ("CS  Technology")  in exchange for  royalties of 4% of net
sales by the  Company  of any  products  based  upon the CS  Technology.  The 4%
royalty shall be payable only after the amount of royalties that would have been
paid  exceeds  the amount of  advances  made by the  Company  to the  Subsidiary
through the date of the spin off.

Board Recommendation

         
                                      -22-


<PAGE>



     The Board of Directors of the Company and  management  of TheraMed  believe
that the spin off will be  beneficial  to Company  stockholders  because it will
enable the stockholders to directly own the Subsidiary. As noted above, the spin
off  is a  condition  to  effectuation  of the  TheraMed  acquisition.  For  the
foregoing reasons, the Board of Directors recommends a vote FOR this proposal.

         PROPOSAL SEVEN: RATIFICATION OF INDEPENDENT PUBLIC ACCOUNTANTS

         The Board of Directors  has  appointed  Berry,  Dunn,  McNeil & Parker,
Manchester,  New  Hampshire,  to  serve  as  the  Company's  independent  public
accountants  for  the  1997  fiscal  year,   subject  to  the  approval  of  the
stockholders.  Berry, Dunn, McNeil & Parker examined the Company's  consolidated
financial  statements  for the fiscal year ended June 30, 1996 and is considered
well qualified.

         It is expected that a representative  of Berry,  Dunn,  McNeil & Parker
will be present at the Stockholders'  Annual Meeting.  The  representative  will
have  an  opportunity  to  make a  statement  if he  desires  to do so and it is
expected  that he will be  available  to respond  to  appropriate  questions  by
stockholders.

         The Board of Directors recommends that you vote FOR the ratification of
the  selection  of Berry,  Dunn,  McNeil & Parker as the  Company's  independent
public accountants for the 1997 fiscal year.

         If the stockholders do not ratify the selection of Berry,  Dunn, McNeil
& Parker as independent  accountants,  the selection of such accountants will be
reconsidered by the Board of Directors.

Changes in and  Disagreements  with Accountants on Accounting and Financial
Disclosure

         Except  as  set  forth  below,   there  have  been  no  changes  in  or
disagreements  with  accountants  with respect to  accounting  and/or  financial
disclosure.

         On  September  26,  1994,  the  Company  terminated  Coopers  & Lybrand
("Coopers") as its certifying  accountant and retained Smith,  Batchelder & Rugg
as  its  certifying  accountant.  In  February  1995,  Smith  Batchelder  & Rugg
affiliated  with Berry,  Dunn,  McNeil and Parker who now express opinion on the
Company's Financial Statements.

         In  connection  with the  audits  of the  financial  statements  of the
Company for the fiscal  years ended June 30, 1992 and 1993 and during the period
commencing  July  1,  1993  through  the  date  of this  report,  there  were no
disagreements with Coopers on any matter of accounting  principles or practices,
financial  statement   disclosure,   or  auditing  scope  or  procedure,   which
disagreements, if not resolved to the satisfaction of Coopers, would have caused
them to make  reference  to the  subject  matter  of the  disagreement  in their
report.

     Except for an explanatory  paragraph  concerning  the Company's  ability to
continue  as a going  concern,  neither of  Coopers'  reports  on the  Company's
financial  statements for the fiscal years ended June 30, 1992 or 1993 contained
an  adverse  opinion  or  disclaimer  of  opinion,  nor was it  qualified  as to
uncertainty,  audit scope or accounting principles.  However, there were certain
reportable events as follows:

                                      -23-


<PAGE>

         (i) The Company's  Annual report on Form 10-KSB for the year ended June
30, 1993 ("1993 Form  10-KSB") was filed with the  Commission  on September  28,
1993. Coopers' report on the financial statements contained therein contained an
explanatory  paragraph relating to uncertainty  concerning the Company's ability
to continue as a going  concern  which  situation  was  further  discussed  in a
footnote to the financial statements.  During the period of preparation of these
financial  statements,  the  Company  was  engaged  in a "best  efforts"  public
offering to raise additional capital.

         Two unsigned  draft reports and  associated  footnotes were prepared by
Coopers,  one without a going  concern  explanatory  paragraph to be used if the
offering was completed  before  Coopers'  report was released,  the other with a
going concern  explanatory  paragraph if the offering was not completed.  By the
release date of Coopers'  report,  the offering had been  terminated and Coopers
released their signed report with the going concern  explanatory  paragraph.  As
noted above, the Company's 1993 Form 10-KSB contained the explanatory  paragraph
and related footnote disclosure.

         Sometime  later,  the  Company's  annual  report to  shareholders  (the
"Annual  Report")  was  printed  and, on or about  January 4, 1994,  was sent to
shareholders.  Through an administrative  oversight,  a disk containing a report
(unsigned)  which did not  include a going  concern  explanatory  paragraph  and
financial  statements  which did not contain  related  footnote  disclosure  was
released to the printer. This oversight was discovered during the preparation of
the 1994 Financial  Statements by the Company in reviewing it past Annual Report
with its then newly retained Auditors, Smith Bachelder & Rugg.

         The Company  immediately  notified  Coopers  who, in turn,  advised the
Company that, in their  opinion,  the Company  should inform the  Commission and
anyone who may be relying on the Annual  Report of this  situation.  The Company
informed  the  former  accountant  that,  due to the  length  of time  since the
distribution of Annual Reports to  shareholders,  the filing with the Commission
of the correct  information  in the  Company's  1993 Form 10-KSB and  subsequent
filings  with the  Commission,  the Company was of the opinion that no one could
reasonably  still be relying  on the Annual  Report.  Accordingly,  the  Company
disclosed this situation in connection  with the filing of the Company's  Annual
Report on Form 10-KSB for the year ended June 30, 1994.

         (ii) In connection with consultations with Coopers concerning its March
1994 purchase of preferred  stock of Genesis  Capital  Corporation  (now Genesis
Farms,Inc.) (see "Interest of Management and Others in Certain  Transactions and
Proposals"),  due to the  materiality  of the  purchase,  Coopers  informed  the
Company  that the value  assigned  to the  Company's  holding  of that  stock as
presented in the Form 10-QSB for the quarter  ended March 31, 1994 would need to
be evaluated in connection with an audit of the Company's  financial  statements
and that  additional  documentation  might be  necessary  concerning  the  value
assigned to that investment if the Company's existing documentation proved to be
inadequate.

         Neither  of the above  two  issues  were  considered  in the  Company's
decision to terminate  Coopers.  The decision to change accountants was approved
by the Board of Directors of the Company.

                                      -24-


<PAGE>

         On July 28, 1992, the Company had engaged  Coopers to be its certifying
accountant  in place of Bradshaw,  Smith & Co.  ("former  accountant"),  who was
dismissed effective July 28, 1992.

         During the two fiscal years ended June 30, 1991  (periods for which the
former  accountant  audited the Company's  financial  statements) and during the
period from July 1, 1991  through the date hereof,  there were no  disagreements
with the former accountant on any matter of accounting  principles or practices,
financial  statement   disclosure,   or  auditing  scope  or  procedure,   which
disagreements,  if not resolved to the  satisfaction  of the former  accountant,
would have caused it to make reference to the subject matter of the disagreement
in connection with its reports.

         The former accountant's  report on the Company's  financial  statements
for  either of the two fiscal  years  ended June 30,  1991 did not  contain  any
adverse  opinion  or  disclaimer  of  opinion,   nor  was  it  qualified  as  to
uncertainty, audit scope or accounting principles.

         The  decision  to engage  Coopers as set forth above and to dismiss the
former  accountant  was  made by the  new  Board  of  Directors  of the  Company
subsequent to the reorganization of the Company and the Subsidiary.  Coopers was
the Subsidiary's independent auditors.

PROPOSALS OF STOCKHOLDERS FOR THE 1997 ANNUAL MEETING

         Proposals of  stockholders  of record to be presented for a vote at the
1997 Annual Meeting of  Stockholders,  tentatively  scheduled for December 1997,
must be received at the principal  executive office of the Company,  10 Chestnut
Drive, Unit D, Bedford, New Hampshire 03110, not later than June 30, 1997, Attn:
Corporate Secretary.

ANNUAL REPORT ON FORM 10-KSB

         A COPY OF THE  COMPANY'S  ANNUAL  REPORT ON FORM  10-KSB FOR THE FISCAL
YEAR ENDED JUNE 30,  1996,  FILED BY THE COMPANY  WITH THE  COMMISSION,  WILL BE
FURNISHED,  WITHOUT  EXHIBITS,  WITHOUT  CHARGE TO ANY PERSON  REQUESTING A COPY
THEREOF IN WRITING AND STATING THAT SUCH PERSON IS A BENEFICIAL HOLDER OF SHARES
OF COMMON  STOCK OF THE  COMPANY  ON THE RECORD  DATE FOR THE ANNUAL  MEETING OF
STOCKHOLDERS. REQUESTS AND INQUIRIES SHOULD BE ADDRESSED TO BIORELEASE CORP., 10
CHESTNUT DRIVE, UNIT D, BEDFORD, NEW HAMPSHIRE 03110.

OTHER MATTERS

     The Board of Directors  knows of no business  constituting a proper subject
for action by the stockholders  which will be presented for consideration at the
meeting other than that shown above.  However,  if any other business shall come
before the meeting,  the persons  named in the  enclosed  form of proxy or their
substitutes will vote said proxy with respect to any such business in accordance
with their best judgment.

                                      -25-


<PAGE>

DOCUMENTS INCORPORATED BY REFERENCE

         The  following  sections  of  the  Company's  1996  Annual  Report  are
incorporated by reference herein: The audited consolidated  financial statements
as and for the fiscal years ended June 30, 1994,  1995 and 1996,  the  unaudited
consolidated financial statements as of and for the three months ended September
30,  1996  and  1995  and  "Market  For  Company's  Common  Equity  And  Related
Stockholder  Matters." A copy of the Company's  1996 Annual  Report  accompanies
this Proxy Statement.

BY ORDER OF THE BOARD OF DIRECTORS


Richard Schubert, Chairman

[BIOI0043.116]

                                      -26-


<PAGE>


                   STOCK PURCHASE AND REORGANIZATION AGREEMENT
                                  BY AND AMONG
                                BIORELEASE CORP.
                                       AND
                                 R. BRUCE REEVES
                                       AND
                             THERAMED PARTNERS, INC.
                              AND ITS SHAREHOLDERS
               DONALD E. STRANGE, PAUL LEIBOWITZ AND NIGEL FLEMING



                                                Dated as of November 7, 1996


<PAGE>
              
                   STOCK PURCHASE AND REORGANIZATION AGREEMENT

         THIS STOCK PURCHASE AND REORGANIZATION AGREEMENT,  dated as of November
7, 1996, is entered into by and among Biorelease  Corp., a Delaware  corporation
("Buyer"),  R. Bruce  Reeves  ("Reeves"),  Theramed  Partners,  Inc., a Delaware
corporation  (the  "Company")  and Donald E.  Strange,  Nigel  Fleming  and Paul
Leibowitz, the sole shareholders of the Company (the "Sellers").

         WHEREAS,  the  Buyer  wishes to  acquire  the  Company  by means of the
delivery to the Sellers of  4,125,000  shares of Buyer's  common stock $.001 par
value per share, in exchange for all of the issued and outstanding  Common Stock
of the Company (the "Merger")  pursuant to Section  368(a)(1)(B) of the Internal
Revenue Code of 1986,  as amended  (the  "Code")  upon the terms and  conditions
hereinafter set forth;

     WHEREAS,  upon the Closing  hereunder  the Company  will be a  wholly-owned
subsidiary of the Buyer; and

         WHEREAS,  upon the Closing or,  shortly  thereafter,  ownership  of the
Buyer's subsidiary  corporation  Biorelease  Technologies,  Inc. ("BTI") will be
"spun out" to certain existing shareholders of the Buyer as more fully described
in paragraph 5.3 below.

         NOW,  THEREFORE,  in  consideration  of the foregoing and of the mutual
promises set forth herein, the parties hereto agree as follows:


                             PURCHASE CONSIDERATION

         Each share of the Company's  outstanding common stock as of the Closing
Date as set forth on Schedule 1.1 hereto shall be exchanged  for 2,750 shares of
the voting  common stock of the Buyer to be delivered at Closing to the Sellers.
The Sellers shall have "piggy back" registration  rights commencing one (1) year
after Closing.

         Options to purchase 420 shares of the Company's common stock granted to
the Company's  consultant,  R.T. Robertson  Consultants,  shall be exchanged for
options to purchase  1,155,000 shares of the Buyer's common stock. One third (33
1/3%) of the options shall be  exercisable  immediately  and one third (33 1/3%)
shall vest and be exercisable on each of the two subsequent anniversary dates of
this Agreement.

         Any  shares of  common  stock  held in the  Company's  treasury  at the
Closing Date shall be canceled without payment of any consideration therefor and
without any conversion thereof.

         All  issued and  outstanding  shares of common  stock,  $.001 par value
share,  of Buyer as of the Closing Date shall remain  outstanding  as issued and
outstanding shares.




                                       
<PAGE>


                                    ARTICLE 2

                         REPRESENTATIONS AND WARRANTIES

                      OF THE COMPANY AND DONALD E. STRANGE

     The  Company  and the  Seller  Donald E.  Strange,  jointly  and  severally
represent and warrant,  (as to Donald E. Strange to the best of his  Knowledge),
as follows:

         Organization  and  Qualification.  The  Company is a  corporation  duly
organized,  validly existing and in good standing under the laws of the State of
Delaware and has all  requisite  corporate  power and  authority to carry on its
business as currently conducted and to own or lease and operate its properties.

         Title to Shares. All of the outstanding shares of the Company are owned
by the Sellers and will be owned as of the Closing Date and shall be free of all
liens, pledges,  security interests,  claims and encumbrances of any nature. The
Sellers and the Company have the full power,  authority and legal right to sell,
transfer or otherwise  dispose of the shares in accordance  with this  Agreement
and to perform their obligations hereunder.

         Capitalization of the Company.

         The authorized  capital stock of the Company  consists of 10,000 shares
of common  stock,  par value  $.001 per share,  of which 1500 will be issued and
outstanding as of closing and upon conversion of the principal amount of certain
promissory  notes by the Sellers  Donald E. Strange and Nigel  Fleming to common
stock of the Company and 420 shares are subject to issuance upon the exercise of
certain options granted to R. T. Robertson Consultants.
No shares of the Company are held in the treasury of the Company.

         Except as set forth on Schedule  1.1 hereof,  the Company does not have
outstanding,  and is not bound by, any  subscription,  option,  warrant or other
right, call or commitment to issue, or any obligation or commitment to purchase,
any of its shares or any securities  convertible into or exchangeable for any of
its shares with the exception of options to purchase 420 shares of the Company's
common stock granted to R.T. Robertson Consultants.

         Certificate of Incorporation,  By-Laws and Corporate Records. Copies of
the Certificate of Incorporation  and the By-Laws of the Company which have been
heretofore  provided to Buyer, are true copies of such instruments as amended to
date, and such instruments are in full force and effect on the date hereof.

         Subsidiaries  and  Affiliates.  The Company  does not own,  directly or
indirectly, any shares of capital stock, or any partnership,  membership,  joint
venture or equitable or similar interest.

         Consents and Approvals; Conflicts.

         No consent,  approval or  authorization  of, or declaration,  filing or
registration  with,  any third party,  including  any  government  or regulatory
authority,  is required in  connection  with the  execution and delivery of this
Agreement by the Company or the Sellers and the consummation of the transactions
contemplated hereby.

         Neither  the  execution   and  delivery  of  this   Agreement  nor  the
consummation  of the  transactions  contemplated  hereby will (i) conflict with,
result in a breach of or constitute a default under any of the terms, conditions
or provisions of the  Certificate  of  Incorporation  or By-Laws of the Company,
(ii) violate any law,  order,  judgment or decree to which any of the  Company's
properties  or assets are bound;  (iii)  violate or  constitute a default  under
(whether  after the  giving of notice,  passage of time or both),  or permit the
termination  of, or impair any rights or increase any obligations of the Company
under,  any  agreement or instrument to which the Company is a party or by which
any part of the  Company's  properties  or assets is bound or (iv) result in the
acceleration  of the maturity of any debt or obligation of the Company or in the
creation  or  imposition  of any  lien,  charge or  encumbrance  upon any of the
properties or assets of the Company.

         Real Property.

         Owned Real Property.  The Company does not own any real property.

         Leased Real Property.  The Company does not lease any real property.

         Taxes. The Company has filed or caused to be filed all federal,  state,
local and foreign income and other Tax returns  required under applicable law to
be filed  on or  before  the  Closing  Date,  and the  Company  has paid or made
provision  for all Taxes and other  charges which have or may become due for the
periods  covered by such returns;  all such returns are true and correct.  There
have been no adverse  adjustments as a result of any audit or investigation  and
none  of  the  tax  returns  or  reports  of  the  Company  is  currently  under
investigation  or audit to the  Knowledge of the Company and the Sellers.  There
are no  outstanding  agreements or waivers  extending  the  statutory  period of
limitations  applicable to any Tax return for any period.  The Company has never
been,  nor is the  Company  currently  party to, any  agreement  relating to the
sharing of any liability for, or payment of, Taxes with any other Person.

         Litigation.  There is no  action,  suit,  proceeding  or  investigation
pending,  at  law  or in  equity,  before  any  arbitrator  or  court  or  other
governmental authority, nor any outstanding judgment, decree, injunction,  award
or order, against or in any manner involving the Company or any of the Company's
assets.

         Brokers.  No broker,  finder or investment banker has acted directly or
indirectly  for the Seller or the Company in connection  with this  Agreement or
the transactions contemplated hereby.

         Environmental Matters. No Hazardous Substances have been or are stored,
treated,  disposed of, managed,  generated,  manufactured,  produced,  released,
emitted or discharged by the Company so as to (i) require,  under any applicable
law or treaty, a governmental approval,  consent, waiver,  exemption,  variance,
franchise,  order,  permit,  authorization,  right or license  (an  "Approval"),
unless such  Approval has been  obtained and remains in full force and effect or
(ii)  render  the  Company's  Premises  in  violation  of  any  applicable  law,
regulation,  or  permit  or  subject  to any  obligation,  liability,  order  or
requirements for remediation.

         Securities  Act  Exemption.  The Sellers  acknowledge  that the Buyer's
common stock to be delivered at Closing will be delivered  without  registration
by the Buyer of the offering and sale of same under the Securities  Act, and may
not be resold by the Buyer  unless  (i) a  registration  is in effect  under the
Securities  Act with respect to such  securities or (ii) an exemption  from said
registration is possible under the Securities Act.

         Disclosure.  To the knowledge of the Company or Donald E.  Strange,  no
representation  or warranty in this  Agreement  or in any other  certificate  or
document  distributed  to the Buyer or its  representatives  contains any untrue
statement of a material  fact or omits to state any material  fact  necessary to
make the statements  herein or therein not misleading.  Unless this Agreement is
terminated or this  provision is partially or entirely  waived in writing by the
Buyer, each of the  representations  and warranties  contained in this Agreement
shall be deemed to have been  reaffirmed  by the Seller and Donald E. Strange as
of the Closing Date.

         No Reliance.  The Sellers hereby  acknowledge that they have not relied
on any  representation,  written or oral,  made by the Buyer or Reeves as to the
marketability  of the  Common  Stock  to be  delivered  at  Closing,  or the tax
consequences of this transaction.

         Access  to  Information.  The  Sellers  acknowledge  that they have had
access to such  materials  concerning the Buyer as were necessary to permit them
to fully  evaluate the merits and risks of their  investment.  In evaluating the
suitability  of  this   investment,   the  Sellers  have  not  relied  upon  any
representations made by the Buyer, except as set forth in this Agreement.

         Financial  Statements.  The Company has previously  furnished the Buyer
with interim financial statements ("Financial  Statements") of the Company as of
September 30, 1996.  The Financial  Statements and the books of account on which
they are based fully and accurately  reflect all financial  transactions  of the
Company for the periods  covered and fairly  present the financial  condition of
the Company as at the dates thereof and the results of its  operations  and cash
flows for the periods then ended.

         Absence  of  Undisclosed  Liabilities.  The  Company  does not have any
debts,  liabilities  or obligations of any nature  (whether  absolute,  accrued,
unliquidated,  contingent  or  otherwise,  and  whether  due or to become  due),
including  Taxes,  other  than  those  which (i) are set  forth  and  adequately
reserved for in the Financial Statements,  (ii) have been specifically disclosed
in the Disclosure Schedules,  (iii) are exempt from disclosure in the Disclosure
Schedules pursuant to a materiality threshold contained in this Agreement,  (iv)
have been incurred since the date of the most recent Financial Statements in the
ordinary course of business in amounts and on terms consistent, individually and
in the  aggregate,  with the  Company's  past  practice or (v) are  specifically
contemplated by this Agreement.

         Absence of Changes.  Since June 30,  1996,  the Buyer has  operated its
business only in the usual and ordinary course consistent with past practice and
there has not occurred any event,  condition or circumstance  that has had or is
likely to have a  Materially  Adverse  Effect on the Buyer or its  subsidiaries,
except for such extraordinary changes approved in writing by the parties hereto.


                         REPRESENTATIONS AND WARRANTIES
                             OF THE BUYER AND REEVES

         The Buyer and Reeves,  jointly and severally  represent and warrant (as
to Reeves to the best of his Knowledge) as follows:

         Organization and Qualification.  The Buyer and each of its subsidiaries
are business corporations duly organized,  validly existing and in good standing
under the laws of the State of Delaware and have all requisite  corporate  power
and authority to carry on their businesses as currently  conducted and to own or
lease and operate their properties.

         Authority.  The Buyer has all the  requisite  power to enter  into this
Agreement and to carry out its obligations hereunder. The execution and delivery
of this Agreement and the consummation of the transactions  contemplated  hereby
shall  have  been  duly  authorized  by the  Company's  Board of  Directors  and
Stockholders as of Closing,  and no other proceedings on the part of the Company
are necessary to authorize  the execution and delivery of this  Agreement by the
Buyer and the  consummation's  of  transactions  contemplated  hereby,  and this
Agreement  is a valid and  binding  obligation  of the  Company  enforceable  in
accordance with its terms.

         Title to Shares.  All of the shares to be delivered by the Buyer to the
Sellers at Closing have been duly  authorized  and will be validly  issued as of
the Closing Date and shall be free of all liens,  pledges,  security  interests,
claims and  encumbrances of any nature.  As of the Closing Date, the Buyer shall
have the full power,  authority  and legal right to sell,  transfer or otherwise
dispose of the  shares in  accordance  with this  Agreement  and to perform  its
obligations hereunder, subject at all times to applicable securities laws..

         Capitalization of the Buyer.

         As of October 1, 1996, the authorized  capital of the Buyer consists of
50,000,000 shares of common stock of which 9,471,659 are issued and outstanding;
the Buyer's  shareholders  are listed on  Schedule  3.4(a).  400,000  additional
shares of the Buyer are held in the treasury of the Buyer.

         Except  as set  forth  in  Schedule  3.4(b)  the  Buyer  does  not have
outstanding,  and is not bound by, any  subscription,  option,  warrant or other
right, call or commitment to issue, or any obligation or commitment to purchase,
any of its shares or any securities  convertible into or exchangeable for any of
its shares.

         Certificate of Incorporation,  By-Laws and Corporate Records. Copies of
the  Certificate  of  Incorporation  and  the  By-Laws  of  the  Buyer  and  its
subsidiaries  which have been heretofore  provided to Buyer,  are true copies of
such  instruments as amended to date, and such instruments are in full force and
effect on the date  hereof.  The stock  transfer  books and minute  books of the
Buyer  delivered  or made  available to the Company and the Sellers are true and
complete as of the date hereof.

         Subsidiaries and Affiliates. Except as set forth in Schedule 3.6, there
are no Persons in which the Buyer owns,  directly or  indirectly,  any shares of
capital stock,  or any  partnership,  membership,  joint venture or equitable or
similar interest.

         Financial  Statements.  The Buyer has previously  furnished the Sellers
with the audited financial statements  ("Financial  Statements") of the Buyer as
of June 30, 1996.  The  Financial  Statements  and the books of account on which
they are based fully and accurately  reflect all financial  transactions  of the
Company for the periods  covered,  were  prepared in accordance  with  generally
accepted  accounting  principles  applied on a consistent  basis  throughout the
periods  involved and fairly present the financial  condition of the Buyer as at
the dates  thereof  and the  results  of its  operations  and cash flows for the
periods then ended.

         Absence of Undisclosed  Liabilities.  The Buyer and its subsidiaries do
not have any debts,  liabilities or obligations of any nature (whether absolute,
accrued,  unliquidated,  contingent or  otherwise,  and whether due or to become
due),  including Taxes,  other than those which (i) are set forth and adequately
reserved for in the Financial Statements,  (ii) have been specifically disclosed
in the Disclosure Schedules,  (iii) are exempt from disclosure in the Disclosure
Schedules pursuant to a materiality threshold contained in this Agreement,  (iv)
have been incurred since the date of the most recent Financial Statements in the
ordinary course of business in amounts and on terms consistent, individually and
in the  aggregate,  with  the  Buyer's  past  practice  or (v) are  specifically
contemplated by this Agreement.

         Absence of Changes.  Since June 30,  1996,  the Buyer has  operated its
business only in the usual and ordinary course consistent with past practice and
there has not occurred any event,  condition or circumstance  that has had or is
likely to have a  Materially  Adverse  Effect on the Buyer or its  subsidiaries,
except for such extraordinary changes approved in writing by the parties hereto.

         Real Property.

         Owned  Real  Property.  Schedule  3.10(a)  contains  a list  and  legal
description  of all real property  owned by the Buyer and its  subsidiaries,  if
any. The Buyer and its subsidiaries  have good and marketable title to such real
estate  subject only to such liens,  encumbrances  and defects set forth in said
Schedule 3.10(a).

         Leased Real Property.

                  Schedule 3.10(b) contains a list and legal  description of all
real property leased by the Buyer (the "Leased Premises"), including the name of
the  landlord  or  sublandlord,  a  description  of  the  leased  premises,  the
commencement and expiration dates of the current term, the security deposited by
the Buyer with the  landlord or  sublandlord,  if any,  and the  monthly  rental
(including all base rent and all additional rents); and

                  Each lease  covering the Leased  Premises is in full force and
effect and has not been assigned, modified, supplemented or amended, and neither
the Buyer nor the landlord or  sublandlord  under any Lease is in default  under
any of the Leases,  and no circumstance or state of facts exists which, with the
giving of notice or passage of time,  or both,  would  permit  the  landlord  or
sublandlord under any Lease to terminate any Lease.

         Personal  Property.  Schedule  3.11  contains  a list  of all  tangible
personal property and real property  improvements  (including fixtures) owned by
the Buyer. Such personal  property and real property  improvements are generally
in good  condition  and repair and are  adequate  for the uses to which they are
being put or would be put in the ordinary  course of business and such  personal
property and real property improvements are not in need of maintenance or repair
except for routine  maintenance  and repair and except as  disclosed on Schedule
3.12.

         Agreements.  Schedule 3.12 contains a complete list and  description of
all material  written and oral agreements that either are not terminable at will
without additional liability or which involve more than $10,000 and to which the
Buyer is a party or by which the  Buyer any of the  Buyer's  assets  are  bound,
including,  without  limitation  leases,  licenses,  consulting  and  employment
agreements, loan and other financing agreements, agreements for the purchase and
sale of property  and  services,  reimbursement  and other  third party  payment
agreements,  guarantees, security agreements, franchise agreements,  partnership
and joint venture agreements,  agreements with or among shareholders,  directors
and/or officers of the Buyer, and merger and acquisition  agreements.  Copies of
all agreements  listed in Schedule 3.12 have been delivered or made available to
the Sellers and are true and complete in all  respects.  With respect to each of
the  agreements  listed or  required  to be listed on  Schedule  3.12,  (i) each
agreement  is legally  binding and in full force and effect and (ii) there is no
existing or alleged default or event of default,  nor does there exist any event
or condition which,  with notice or lapse of time or both, would constitute such
a default or event of default by the Buyer.

         Insurance.  Schedule  3.13  lists all  insurance  policies,  including,
without limitation,  workers' compensation,  medical malpractice,  comprehensive
general liability,  life, health, disability and property damage, in force as of
the date  hereof and in force as of the date  hereof and  relating to the Buyer,
its  employees  and its  properties,  including in each instance the name of the
carrier,  the term of the policy, the periods for which it has been continuously
in effect,  the annual premium,  scope of coverage and outstanding  claims.  The
premiums for such insurance  policies are fully paid. None of the policies other
than workers compensation  policies provides for the assessment of additional or
retroactive  premiums,  and there are no loans  outstanding  against any of such
policies.  No  notice  of  cancellation  or  non-renewal  with  respect  to,  or
disallowance of any claim under,  any insurance  policy listed or required to be
listed on  Schedule  3.13 or binder  listed or required to be listed in Schedule
3.13 has been received by the Buyer.  No claim or event which forms the basis of
a claim has  occurred  which could cause the Buyer's  insurers to  substantially
increase the cost of insurance for the Buyer.

         Ownership  of Assets.  The Buyer and its  subsidiaries  own or have the
right to use all  tangible  and  intangible  assets  necessary to the conduct of
business  as  currently  conducted,  and such  assets  are free and clear of all
liens,  encumbrances,  restrictions  and adverse  claims  except as disclosed on
Schedule 3.15.

         Taxes.  Except  as set  forth  on  Schedule  3.15,  The  Buyer  and its
subsidiaries  have  filed or caused to be filed all  federal,  state,  local and
foreign income and other Tax returns  required under  applicable law to be filed
on or  before  the  Closing  Date,  and made  provision  for all Taxes and other
charges  which have or may become due for the periods  covered by such  returns;
all such returns are true and correct. There have been no adverse adjustments as
a result of any audit or investigation and none of the tax returns or reports of
the Buyer is  currently  under  investigation  or audit to the  knowledge of the
Buyer and the Seller.  There are no outstanding  agreements or waivers extending
the statutory period of limitations applicable to any Tax return for any period.
The Buyer has never been,  nor is the Buyer  currently  party to, any  agreement
relating to the  sharing of any  liability  for,  or payment of,  Taxes with any
other  Person.  Schedule  3.15 sets forth all state  jurisdictions  in which the
Buyer or its  subsidiaries  have filed or expect to file income or franchise Tax
returns for each taxable  period,  or portion  thereof,  ending on or before the
Closing Date. All Taxes owed by the Buyer or its subsidiaries have been paid.

         Litigation.  Except as disclosed in Schedule 3.16,  there is no action,
suit proceeding or investigation  pending,  or threatened,  at law or in equity,
before  any  arbitrator  or  court  or  other  governmental  authority,  nor any
outstanding  judgment,  decree,  injunction,  award or order,  against or in any
manner involving the Buyer, its subsidiaries or any of the Buyer's or any of its
subsidiaries' assets.

         Compliance  with Laws,  Etc.  Except as disclosed in Schedule 3.17, the
Buyer,  its subsidiaries and their employees have complied and are in compliance
with (i) all judgments,  orders, rulings,  injunctions,  decrees and settlements
issued  by or with  any  court,  administrative  agency  or  other  governmental
authority  or  agency,  (ii)  all  permits,   licenses,   franchises  and  other
governmental  authorizations  and  (iii)  all  federal,  state  and  local  laws
applicable  to the  Buyer or any of its  operations,  employees,  properties  or
assets.

         Intellectual  Property. The Buyer owns, or is licensed or otherwise has
the full right to use, all patents,  trademarks,  trade  names,  service  marks,
copyrights,  technology, know-how and processes or confidential information used
in the conduct of its business as currently conducted.  Schedule 3.18 contains a
complete list of all  registered and  unregistered  patents,  trademarks,  trade
names, service marks and copyrights used by the Buyer, all applications therefor
and all licenses and other agreements  relating thereto,  which are owned by the
Buyer or used in the  business  of the Buyer.  No claims  have been  asserted or
threatened  against  the  Buyer  with  respect  to the  use of its  Intellectual
Property.

         Employee Benefit Plans. Schedule 3.19 sets forth a list of all employee
benefit Plans  maintained by the Buyer.  The Buyer does not currently  maintain,
contribute  to or have any liability  with respect to any other Plan.  The Buyer
does not  contribute  to any such Plan for the benefit of persons not  currently
employed by the Buyer,  except to the extent  required under Title X of COBRA or
any other  applicable  law.  Each  Pension  Plan (as defined in ERISA) meets the
requirements  under  Section  401(a)  of the  Code  for  qualification  and  the
immediate termination of any such Plan shall not cause such Plan to fail to meet
these qualification requirements. The Buyer has made all contributions and other
payments which it is required to make with respect to said Plans,  including all
contributions  and payments with respect to the current Plan year for the period
ending on the  Closing  Date.  Each of said  Plans has been  operated  and is in
compliance with all provisions of applicable law,  including without  limitation
ERISA and the Code.  Neither the Buyer nor any fiduciaries or  administrators of
said Plans have any liability for any failure to comply with any applicable law,
including  without  limitation  laws requiring full funding of said Plans,  laws
requiring  appropriate  administration  of  said  Plans,  laws  prohibiting  any
"prohibited  transaction"  as defined in Section 406 of ERISA or Section 4975 of
the Code and the like.

         Banks.  Schedule  3.20  contains a correct and  complete  list of every
bank, savings and loan or other financial institution in which the Buyer has any
accounts or lock boxes and the corresponding account  identification  number, if
any, and the names of Persons  authorized to make withdrawals  therefrom or have
access thereto.

         Accounts  Receivable.  The  accounts  receivable  of the  Buyer and its
subsidiaries  have  arisen  from the bona  fide  rendering  of  services  in the
ordinary  course of the  business of the Buyer and are not in dispute or subject
to  any  contractually  provided  setoffs,  discounts,  credits,  reductions  or
counterclaims  and, the Buyer and Reeves  reasonably  expect that with usual and
ordinary collection efforts all such accounts,  will be paid in full (net of any
reserves  reflected  on the  Financial  Statements)  within  one year  after the
Closing Date, without resort to legal action. All billing practices of the Buyer
have been in accordance  with  applicable  rules and  procedures  established by
third party payors.

         Customers.  Schedule 3.22 sets forth all customers of each of the Buyer
and its  subsidiaries  who were billed $1,000 or more during the Buyer's  fiscal
year ended June 30, 1996 showing the approximate  total billings by the Buyer to
each such customer during such period.

         Brokers.  No broker,  finder or investment banker has acted directly or
indirectly for the Buyer in connection  with this Agreement or the  transactions
contemplated  thereby and no commission on other similar  payment will be due to
any third party in connection therewith.

         Securities Act  Exemption.  The Buyer  acknowledges  that the Company's
common  stock  will be  delivered  without  registration  by the  Sellers of the
offering and sale of the same under the Securities Act, pursuant to an exemption
from  registration  available under such Act, and may not be resold by the Buyer
unless (i) a  registration  statement is in effect under the Securities Act with
respect  to such  securities  or (ii) an  exemption  from such  registration  is
available under the Securities Act.

         Access to Information.  The Buyer  acknowledges  that it has had access
to, and has carefully  reviewed,  such materials  concerning the Company as were
necessary  to  permit  him  to  fully  evaluate  the  merits  and  risks  of his
investment.  In evaluating the suitability of making this investment,  the Buyer
has not relied upon any representations or warranties made by the Company or the
Seller's,  except as set forth in this Agreement, and Buyer acknowledges that no
such  other  representations  or  warranties  have  been  made to it,  or to its
advisors (if applicable).

         Environmental  Matters.  Except  as set  forth  on  Schedule  3.26,  No
Hazardous  Substances  have been or are stored,  treated,  disposed of, managed,
generated, manufactured,  produced, released, emitted or discharged by the Buyer
or its so as to (i) require,  under any applicable law or treaty, a governmental
approval,  consent,  waiver,  exemption,  variance,  franchise,  order,  permit,
authorization,  right or license (an "Approval"),  unless such Approval has been
obtained  and  remains  in full  force and  effect or (ii)  render  the  Buyer's
Premises in violation of any applicable law, regulation, or permit or subject to
any obligation, liability, order or requirements for remediation.

         Disclosure.  To the knowledge of Buyer or Reeves,  no representation or
warranty by the Buyer or Reeves in this Agreement  contains any untrue statement
of a material  fact or omits to state any  material  fact  necessary to make the
statements herein or therein not misleading. Unless this Agreement is terminated
or this  provision is  partially  or entirely  waived in writing by the Sellers,
each  of  the  representations  and  warranties   contained  in  this  Agreement
(including,  without  limitation,  the Disclosure  Schedules) shall be deemed to
have been reaffirmed by the Buyer and Reeves as of the Closing Date.


                     CONDITIONS PRECEDENT TO THE OBLIGATIONS
                                    OF BUYER

         The  obligations  of  Buyer  to  close  the  transactions  contemplated
hereunder are subject to fulfillment, to the Buyer's reasonable satisfaction, at
or prior to the Closing, of all of the following conditions:

         Representations and Warranties True. The representations and warranties
contained in Article 2 hereof, and in any certificates  delivered by the Sellers
or the Company to Buyer pursuant hereto or in connection  with the  transactions
contemplated  hereby  shall be true as of the date when made and shall be deemed
to be  made  again  at  and as of the  Closing  Date  and  (except  for  changes
contemplated by this Agreement) shall then be true.
         Performance of Covenants. The Sellers shall have performed and complied
with each  covenant,  agreement and condition  required by this  Agreement to be
performed or complied with or by them prior to or on the Closing Date.

         No Governmental or Other Proceeding. As of the Closing, there shall not
be any effective  injunction,  writ or temporary  restraining order or any other
order of any  nature  issued  by a court or  governmental  agency  of  competent
jurisdiction  directing that the transactions provided herein or any of them not
be consummated as herein provided or any action,  suit or proceeding  pending or
threatened  before any court or governmental body with respect to which there is
a reasonable  possibility that such action,  suit or proceeding could prevent or
substantially  delay the  consummation of any of the  transactions  contemplated
herein,  cause any of such  transactions to be rescinded or limit in any way any
of the Buyer's rights to exercise any of its rights hereunder as shareholders of
the Company.

         Sellers shall have executed an appropriate "investment letter" pursuant
to  which  each  Seller  acknowledges  that  (i)  he is  acquiring  the  Buyer's
securities  for his own account not with a view to resale or  distribution  (ii)
that he has no present agreement to distribute sell, assign or otherwise dispose
of same;  and (iii) that he cannot  pledge,  sell or assign the  Buyer's  common
stock without registration under appropriate securities laws unless an exemption
from such registration is available.

         Sellers' Certificate. Buyer shall have received a certificate dated the
Closing Date,  signed by the Sellers,  certifying as to the  satisfaction of the
conditions set forth in this Article 4.

          Other  Documents,  Etc.  Buyer shall have received from the Company or
     the Sellers all other  certificates,  documents,  etc. which the Company or
     the Sellers are required to deliver pursuant to Section 6 hereof.

         The Buyer shall have been duly  authorized  by the  Company's  Board of
Directors  and   Stockholders   as  of  Closing  to  complete  the   transaction
contemplated herein.


                     CONDITIONS PRECEDENT TO THE OBLIGATIONS
                                 OF THE SELLERS

         The obligations of the Sellers to close the  transactions  contemplated
hereunder are subject to fulfillment,  to the Sellers' reasonable  satisfaction,
at or prior to the Closing, of all of the following conditions:

         Representations and Warranties True. The representations and warranties
contained in Article 3 hereof and in all certificates  delivered by Buyer to the
Sellers or the Company  pursuant hereto or in connection  with the  transactions
contemplated  hereby  shall be true as of the date when made and shall be deemed
to be made again at and as of the Closing Date (except for changes  contemplated
by this Agreement) shall then be true.

         Performance of Covenants.  Buyer shall have performed and complied with
each  covenant,  agreement  and  condition  required  by  this  Agreement  to be
performed or complied with by it prior to or on the Closing Date.

         Approvals.  All approvals,  consents,  authorizations  and waivers from
governmental and other  regulatory  agencies and other third parties required to
consummate all the transactions  contemplated  hereby including  approval by the
Buyer's  stockholders  of the  purchase of Sellers'  common stock of the Company
hereby as well as the  approval  by the  stockholders  of the "spin  off" of BTI
pursuant  to the  terms set  forth  below,  and such  approval  shall  have been
obtained  prior to Closing  consistent  with advances of funds to be made by the
Company to the Buyer in order to obtain such approval but without any additional
material expense to Sellers or the Company.

         The  stockholders  of the Buyer shall duly  approve and  authorize  the
"spinning off" of 100% of Buyer's  ownership of BTI to such  stockholders of the
Buyer who are stockholders of record on the day prior to Closing.  In connection
with this spin off, BTI will grant Buyer an exclusive license,  subordinate only
to the  existing  rights  licensed  to  Baxter  Healthcare  for the use of BTI's
Chrondrotin Sulfate Technology ("CS Technology") in exchange for royalties of 4%
of all net  sales by Buyer of any  products  based  upon CS  Technology.  The 4%
royalties  shall be payable only after the amount of  royalties  that would have
been paid  exceed the amount of  advances  made by the Buyer to BTI prior to the
date of the spin off.

         Amendment to Buyer's  Certificate of  Incorporation.  Prior to Closing,
Buyer's  Certificate  of  Incorporation  shall be  amended  to:  (i)  change the
corporate name of Buyer to Pharmatrage Holdings,  Inc.; (ii) authorize a reverse
stock  split of  Buyer's  issued  and  outstanding  shares of Common  Stock on a
one-for-four  basis; and (iii) authorize for future issuance preferred stock the
designations,  rights and  preferences  of which to be determined by the Buyer's
Board of Directors after Closing.

          Consulting Agreement with R. T. Robertson  Consultants,  Inc. Prior to
     Closing,  the Company shall have executed a consulting agreement with R. T.
     Robertson  Consultants  which  shall be for a period of three (3) years and
     upon such  other  terms and  conditions  including  the  issuance  to R. T.
     Robertson  Consultants of additional options to purchase the Buyer's Common
     Stock as set forth in Article 9.

         No Governmental or Other Proceeding. As of the Closing, there shall not
be any effective  injunction,  writ or temporary  restraining order or any other
order of any  nature  issued  by a court or  governmental  agency  of  competent
jurisdiction  directing that the transactions provided herein or any of them not
be consummated as herein provided or any action,  suit or proceeding  pending or
threatened  before any court or governmental body with respect to which there is
a reasonable  possibility that such action,  suit or proceeding could prevent or
substantially  delay the  consummation of any of the  transactions  contemplated
herein or cause any of such transactions to be rescinded.

         Buyer's  Certificate.  The Sellers  shall have  received a  certificate
dated as of the  Closing  Date  from  Richard  F.  Schubert,  Chairman  of Buyer
certifying as to the satisfaction of the conditions set forth in this Article 5.

          Other  Documents,  Etc. Sellers shall have received from the Buyer all
     other certificates,  documents, etc. which the Buyer is required to deliver
     pursuant to Section 6 hereof.


                                   THE CLOSING

         Time and Place of Closing.  The  consummation  (the  "Closing")  of the
other  transactions  contemplated  by this  Agreement  shall  take  place at the
offices of Warner & Stackpole at 10:00 A.M. local time on __________, 1996 or at
such other place and time as may be mutually  acceptable to the parties  hereto.
The "Closing  Date" as used herein shall be deemed to mean  __________,  1996 or
such other date and time as is mutually acceptable to the parties.

         Deliveries by the Sellers. At the Closing, the Sellers shall deliver to
Buyer (i) all  certificates  representing  their shares of the Company's  common
stock, free and clear of any lien, pledge, charge, encumbrance, claim, option or
equity,  duly  endorsed  in  blank  or  accompanied  by  stock  powers  or other
instruments of transfer duly executed in blank,  (ii) all certificates and other
documents set forth in Article 5 hereof,  (iii) certified  copies of resolutions
of the Company's  board of directors and  shareholders  approving this Agreement
and the transactions  contemplated  hereby, (iv) certificates of existence dated
as of or near the  date of the  Closing  Date  from  the  Secretary  of State of
Delaware,  (v)  incumbency   certificates  and  (vi)  such  other  documents  or
instruments as Buyer is authorized to request  pursuant to the specific terms of
this Agreement or may otherwise  reasonably  request to effect the  transactions
contemplated hereby.

         Deliveries by Buyer. At the Closing,  Buyer shall deliver to the Seller
(i)  certificates  representing an aggregate of 4,125,000  shares of the Buyer's
common stock and an option agreement to the Company's  consultant R.T. Robertson
for options to purchase 1,155,000 of the Buyer's common stock in the name of and
in the amounts and names set forth in Schedule  1.1 hereto,  (ii) good  standing
certificates dated as of or near the Closing Date from the Secretary of State of
Delaware  reflecting the good standing of the Buyer and its subsidiaries,  (iii)
incumbency  certificates,  and (iv) such other  documents or  instruments as the
Company or the Sellers are authorized to request  pursuant to the specific terms
of this Agreement or may otherwise reasonably request to effect the transactions
contemplated hereby;


                                   TERMINATION

                  Termination. Either Buyer, on the one hand, or the Sellers, on
the other hand, may, by written notice given at any time prior to the Closing to
the other, terminate this Agreement if the conditions to such party's obligation
to close set forth in Articles 5 and 6 hereof, respectively, shall not have been
fulfilled as of the Closing Date; provided,  however,  that this provision shall
not be available to a party which has made a material  misrepresentation  or has
materially breached any warranty or covenant. A termination under this provision
shall not prejudice any claim which any party may have  hereunder,  in law or in
equity,  as a  consequence  of any  failure or default by any other party in the
performance of any of its covenants or agreements contained in this Agreement.


                             SURVIVAL AND INDEMNITY

         Survival of  Warranties.  Each  representation  and warranty  contained
herein  (including the  Disclosure  Schedules) or in any  certificate  delivered
pursuant  hereto or in  connection  herewith  shall  survive the  execution  and
delivery of this Agreement and the consummation of the transactions contemplated
by this Agreement. The right to indemnification pursuant to this Agreement shall
survive any investigation made by the parties or their representatives,  lenders
or investors or the receipt of any opinion or certificate.

         Indemnification of Buyer.

         The Company agrees to indemnify, defend and hold Buyer harmless against
and from all Damages incurred by it which are caused directly by or arise out of
(i) the breach of any  representation  or  warranty  made by the  Sellers or the
Company in this Agreement or in any document or certificate  delivered  pursuant
to this  Agreement,  (ii) any breach of any covenant or agreement of the Sellers
or the Company  contained herein or in any agreement entered into by the parties
hereto in connection with the transactions contemplated herein.

         Whenever  Buyer  shall  have  notice  that a claim or  demand  has been
asserted or  threatened by a third party  against  Buyer which,  if true,  would
constitute  a basis for  indemnification  hereunder,  Buyer  shall give  written
notice of such  claim or  demand to the  Company;  provided,  however,  that any
failure by Buyer to give such notice shall not  prejudice the rights of Buyer to
indemnification  hereunder,  except to the extent  that such  failure  adversely
affects the  Sellers' or the  Company's  ability to  investigate  or defend such
claim or demand,  the Buyer shall then have the right,  upon  written  notice to
Buyer  acknowledging  the Company's  obligation  to  indemnify,  defend and hold
harmless  Buyer  under  Section  8.2(b)  hereof  against  and from  all  Damages
resulting  from such claim or demand,  to contest,  negotiate or settle any such
claim or demand through  counsel of its choice and solely at the cost,  risk and
expense  of the  Company;  provided,  however,  (i) that the  Company  shall not
compromise or offer to settle or compromise  any such claim or demand on a basis
which would or could result in the imposition of a consent order,  injunction or
decree that would or could restrict the future  activity or conduct of Buyer and
(ii) Buyer  shall have the right to  participate,  at  Buyer's  expense,  in the
defense of any such claim or demand using  counsel of Buyer's  choosing.  In the
event that (x) the Company shall fail to give the above-mentioned written notice
to Buyer within ten (10) days after Buyer has notified the Company that any such
claim or demand has been asserted or threatened, or (y) such notice is given but
any such claim or demand is not  promptly  settled or  promptly  and  diligently
contested  by the Company,  Buyer shall have the right to satisfy and  discharge
the same by payment,  compromise or  otherwise,  and the Company shall be liable
therefor to Buyer in accordance  with and to the extent  provided by Section 8.2
hereof.

         If Buyer shall have a claim for indemnification which involves a matter
other than a third  party  claim,  the Buyer shall give  written  notice of such
claim or demand to the  Company.  The  Company  shall have  thirty  (30) days to
object to such claim by delivery of a written  notice of such objection to Buyer
specifying in reasonable  detail the basis for such  objection.  Failure to make
timely objection shall constitute a final and binding acceptance of the claim by
the Company,  and the claim shall be paid as provided herein. If an objection is
timely interposed by the Company, then the Buyer and the Company shall negotiate
in good faith for a period of sixty (60)  business  days from the date the Buyer
receives such objection  prior to commencing any formal  proceeding with respect
to such claim.

         Upon final  determination of the amount of a claim for  indemnification
under this Article 8 by the Buyer and the Company,  whether by agreement between
the Buyer and the Company or by  arbitration  award or other  adjudication,  the
Company shall pay the amount of such claim within ten (10) days of the date such
amount is finally determined.  Claims for indemnification  hereunder can only be
asserted by the Buyer  against  the  Sellers or the Company  within one (1) year
hereof.

         Indemnification of the Sellers and the Company.

         Buyer  shall  indemnify,  defend and hold the  Sellers  and the Company
harmless  against and from all Damages  incurred by any of them which are caused
directly  by or arise out of (i) the breach of any  representation  or  warranty
made by Buyer or Reeves in this  Agreement  or in any  document  or  certificate
delivered pursuant to this Agreement or (ii) any breach of any covenant of Buyer
contained  herein or in any  agreement  entered  into by the  parties  hereto in
connection with the transactions contemplated herein.

         Whenever  Sellers  or the  Company  shall have  notice  that a claim or
demand has been asserted or threatened against any of them or it which, if true,
would  constitute  a basis for  indemnification  hereunder,  such  Seller or the
Company  shall give written  notice of such claim or demand to Buyer;  provided,
however,  that any failure to give such notice shall not prejudice the rights of
such Seller or the Company to  indemnification  hereunder,  except to the extent
such failure  adversely  affects  Buyer's  ability to investigate or defend such
claim or demand.  Buyer shall then have the right,  upon written  notice to such
Seller or the Company acknowledging Buyer's obligation to indemnify,  defend and
hold harmless  such Seller or the Company  under Section 8.3 hereof  against and
from all Damages resulting from such claim or demand,  to contest,  negotiate or
settle any such claim or demand through  counsel of its choice and solely at its
cost, risk and expense;  provided,  however, (i) that Buyer shall not compromise
or offer to settle or compromise  any such claim or demand on a basis that would
or could result in the imposition of a consent order, injunction or decree which
would or could  restrict the future  activities or conduct of the Sellers or the
Company and (ii) Sellers or the Company shall have the right to participate,  at
their expense, in the defense of any such claim or demand using counsel of their
choosing.  In the event that (x) Buyer  shall  fail to give the  above-mentioned
written  notice  within ten (10) days after such Buyer has received  notice that
any such claim or demand has been  asserted or  threatened,  or (y) in the event
such  notice is given but any such  claim or demand is not  promptly  settled or
promptly and  diligently  contested by Buyer,  such Seller or the Company  shall
have the right to satisfy  and  discharge  the same by  payment,  compromise  or
otherwise,  and Buyer  shall be liable  therefor in  accordance  with and to the
extent provided by Section 8.3(a) hereof. Sellers or the Company may also defend
any such claim or demand in the event  Buyer  fails to give such  notice  within
such ten day period,  and no actions taken or omitted to be taken by the Sellers
or the Company in  connection  with such defense  shall  affect  Seller's or the
Company's right to full indemnification hereunder.

         If Sellers or the Company shall have a claim for indemnification  which
involves a matter  other than a  third-party  claim,  the Sellers or the Company
shall give written notice of such claim or demand to the Buyer.  The Buyer shall
have thirty (30) days to object to such claim by delivery of a written notice of
such objection to the Sellers or the Company specifying in reasonable detail the
basis for such objection.  Failure to make timely  objection shall  constitute a
final and binding  acceptance of the claim by the Buyer,  and the claim shall be
paid as provided herein. If an objection is timely interposed by the Buyer, then
the Buyer and the  Company or the  Seller  shall  negotiate  in good faith for a
period of sixty (60) business days from the date that the Sellers or the Company
receives such objection  prior to commencing any formal  proceeding with respect
to such claim.

         Upon final  determination  of the  amount of claim for  indemnification
under this  Article 8 by the Buyer and the  Company or the  Sellers,  whether by
agreement  between the Buyer and the Company or the Sellers or by arbitration or
order other  adjudication,  the Buyer shall pay the amount of such claim  within
ten (10)  days of the  date  such  amount  is  finally  determined.  Claims  for
indemnification  hereunder  may only be  asserted  by the Sellers or the Company
against the Buyer within one (1) year hereof.


                                OTHER AGREEMENTS

         Publicity. Prior to the Closing and except as may otherwise be required
by law,  the  parties  hereto  agree that  Buyer and the  Sellers  will  jointly
determine  the  timing  and  content  of any  proposed  press  release or public
announcement and all announcements relating to the transactions  contemplated by
this Agreement and no such press release or  announcement  shall be made without
the written  consent of the other party  except that the Sellers and the Company
recognize that Buyer may be obligated to make certain disclosures under state or
federal securities laws and will cooperate therein.

         Expenses.  Except as otherwise provided in this Agreement,  each of the
parties shall be responsible for all expenses  (including,  without  limitation,
fees and  expenses  of  legal  counsel,  investment  bankers,  brokers  or other
representatives or consultants  engaged by them or it) incurred by such party in
connection with the  transactions  contemplated  hereby (whether  consummated or
not).

         Advance of Funds.  The  Company  has and shall  continue  to advance to
Buyer prior to Closing certain funds for Buyer's professional and other expenses
related to the transaction's  contemplated by this Agreement. The parties hereto
agree  that such  advances  will be deemed to be loans  from the  Company to the
Buyer.  In the event that the  transaction's  contemplated by this Agreement are
not  consummated  by March  31,  1997,  the  loans  will be due on demand by the
Company  not sooner  than July 31,  1997.  If such  loans are not repaid  within
thirty (30) days of written demand by the Company, the Company shall be entitled
to receive one (1) share of common  stock of the Buyer for each $0.085  presplit
or $0.34 postsplit of the principal amount of the loans then outstanding.

         Buyer's  Obligation's  to  R.T.  Robertson  Consultants,   Reeves,  and
Schubert.  Richard F. Schubert, Reeves and R.T. Robertson Consultants will agree
to convert certain outstanding amounts owed to them by the Company as of October
1, 1996 in the aggregate  amount of $102,689.00 to a loan, the principal  amount
of which is due on the  earlier of three (3) years from the  Closing or upon the
Buyer obtaining a working capital level of $2,000,000.

         Additional  Buyer  Options.  The Buyer shall issue  certain  options to
Sellers and to R.T.  Robertson to purchase its common stock at an exercise price
set at the  postsplit  price of $0.34 per share for a term of ten years from the
date of issuance in the following amounts:

         o    195,513 shares upon Buyer becoming listed on AMEX or NASDAQ within
              eighteen months of Closing hereunder.

         o    195,513 shares upon Buyer obtaining a working capital level of 
              $500,000 within nine (9) months of Closing hereunder.

         o    195,513  shares  upon Buyer  completing  an  acquisition  with the
              target Company  having a market value of $5,000,000  within twelve
              months of Closing hereunder.

         o    195,513 shares upon Buyer  obtaining a market  capitalization  for
              thirty consecutive calendar days of $15,000,000 within twenty-four
              (24) months of Closing hereunder.

         Buyer shall reserve for issuance  195,513 options shares for additional
board  members  or  consultants,  to be  engaged by the Buyer from time to time,
other  than to the  Sellers  and R.T.  Robertson  Consultants,  Inc.  Buyer  has
reserved or issued 75,000 of these options to acquire  splitback shares in Buyer
to Jerry  Weisbach in the amount of 37,500 option shares and to Francis  Bullock
in the amount of 37,500 option  shares,  both at an exercise  price of $0.34 per
option  share and both  exercisable  for a term of five  years  from the date of
issue. The remaining  120,513 option shares shall be issued at the discretion of
the Board of Directors of Buyer following Closing.

         Change of Corporate Name to Pharmatrage Holdings, Inc. The Buyer agrees
to take all necessary steps to lawfully change its corporate name to Pharmatrage
Holdings, Inc.


                                  MISCELLANEOUS

         Entire   Agreement.   This  Agreement   (including  the  documents  and
instruments  referred to herein) embodies the entire agreement and understanding
of  the  parties  with  respect  to the  transactions  contemplated  hereby  and
supersedes all other prior  commitments,  arrangements or  understandings,  both
oral and written, between the parties with respect to the subject matter hereof,
other than agreements entered into contemporaneously herewith.

     Binding  Effect.  This Agreement  shall be binding upon, and shall inure to
the benefit of, the parties hereto and their respective successors and permitted
assigns.

     Assignment.  This Agreement  shall not be assignable by operation of law or
otherwise and is not intended to create any obligations to, or rights in respect
of, any Persons other than the parties hereto.

     Governing  Law.  This  Agreement  shall be  governed  by and  construed  in
accordance  with  the  laws of the  State  of  Delaware  without  regard  to its
principles of conflicts of laws.

     Headings.  The headings of the various Articles and Sections herein are for
convenience  of reference only and shall not define or limit any of the terms or
provisions hereof.

         Notices.  Any notices or other  communications  required  or  permitted
hereunder  shall  be in  writing  and  personally  delivered  at  the  addresses
designated below, sent by overnight courier, telecopied to the numbers below, or
mailed by certified mail, return receipt requested,  postage prepaid,  addressed
as follows,  or to such other addresses or numbers as may hereafter be furnished
by one party to the other party in compliance with the terms hereof:

         If to Buyer:

                  Biorelease Corp.
                  10 Chestnut Drive
                  Unit D
                  Bedford, NH  03110

                  Attention:  Richard Schubert, Chairman

         If to the Sellers or the Company:

                  Theramed Partners, Inc.
                  c/o Warner & Stackpole LLP
                  75 State Street
                  Boston, MA  02109

                  Attention:  Donald Strange, Chairman

         All such  notices  and  communications  shall be deemed to be given for
purposes of this  Agreement on the day personally  delivered or telecopied,  one
day after being sent by overnight courier or five (5) days after being mailed.

         Counterparts.   This  Agreement  may  be  executed  in  any  number  of
counterparts each of which, when executed, shall be deemed to be an original and
all of which together shall be deemed to be one and the same instrument.

         Rights  Cumulative.   All  rights,   powers  and  privileges  conferred
hereunder upon a party, unless otherwise provided, shall be cumulative and shall
not be restricted to those given by law.

         Severability  of Provisions.  The provisions of this Agreement shall be
severable  in the event that for any  reason  whatsoever  any of the  provisions
hereof are invalid, void or otherwise  unenforceable.  Any such invalid, void or
otherwise  unenforceable  provisions  shall be  automatically  replaced by other
provisions  which are as similar as possible in terms to such  invalid,  void or
otherwise  unenforceable  provisions  but  are  valid  and  enforceable  and the
remaining provisions shall remain enforceable to the fullest extent permitted by
law.

     Amendment.  This  Agreement  may not be amended  except by an instrument in
writing signed on behalf of each of the parties hereto.

         Extension;  Waiver. At any time prior to the Acquisition,  Buyer on the
one hand,  and the  Sellers on the other  hand,  may (i) extend the time for the
performance  of any of the  obligations or other acts of the other party hereto,
(ii) waive any  inaccuracies  in the  representations  and warranties  contained
herein or in any document delivered pursuant hereto by the other party and (iii)
waive  compliance  with any of the  agreements  or conditions of the other party
contained  herein.  Any agreement on the part of the parties  hereto to any such
extension  or waiver  shall be valid if set forth in  writing  in an  instrument
signed by or on behalf of such consenting  party. The waiver by any party hereto
of a breach of this  Agreement  shall not operate or be construed as a waiver of
any subsequent  breach.  Failure to exercise any power given any party hereunder
or to insist upon strict  compliance  by any other party shall not  constitute a
waiver of any party's right to demand exact compliance with the terms hereof.

         Third  Party  Beneficiaries.   Each  party  hereto  intends  that  this
Agreement  shall not  benefit  or  create  any right or cause of action in or on
behalf of any person other than the parties hereto.


                                   DEFINITIONS

          Definitions.  The  following  terms,  as used  herein,  shall have the
     following meanings:

          "Agreement"   shall  mean  this  Stock  Purchase  and   Reorganization
     Agreement by and among Buyer,  Bruce  Reeves,  the Company and the Sellers,
     including all appendices, exhibits and schedules hereto.

                  "Buyer" shall have the meaning given that term in the preamble
to this Agreement.

                  "Closing  Date"  shall  have the  meaning  given  that term in
Section 6.1 hereof.

                  "COBRA"   shall   mean   the   Consolidated   Omnibus   Budget
Reconciliation Act of 1985, as amended.

                 "Commission" shall mean the Securities and Exchange Commission.

                  "Company"  shall  have  the  meaning  given  that  term in the
preamble to this Agreement.

                  "Damages" shall mean any losses, claims, liabilities, costs or
         expenses (including reasonable attorneys' fees) or other damages of any
         nature.

                  "Disclosure Schedules" shall mean the schedules referred to in
         this Agreement and delivered contemporaneously herewith.

                  "Environmental Laws" shall mean environmental  pollution laws,
         common law or laws relating to the  protection of worker and work place
         health and safety,  including,  without limitation,  CERCLA,  SARA, the
         Resource  Conservation and Recovery Act, the Toxic  Substances  Control
         Act, the  Hazardous  Materials  Transportation  Act,  the  Occupational
         Safety and Health Act, the Consumer Product Safety Act, the Clean Water
         Act,  the Clean Air Act and the National  Environmental  Policy Act, as
         each of the  foregoing  are in effect as of the Closing  Date,  and any
         similar federal, state or local laws, rules or regulations  promulgated
         thereunder.

                  "ERISA" shall mean the Employee Retirement Income Security Act
of 1974, as amended.

                  "Hazardous  Substances"  shall mean solid,  hazardous or toxic
         wastes,  substances or materials,  as those terms are used in the Clean
         Air Act,  Resource  Conservation  and Recovery Act of 1976, as amended,
         the  Hazardous  Materials   Transportation  Act  or  the  Comprehensive
         Environmental   Response,   Compensation  and  Liability  Act  of  1980
         (CERCLA),  as amended by the Superfund  Amendments and  Reauthorization
         Act of 1986  (SARA),  or in any  other  federal,  state or local law or
         ordinance  governing  hazardous,  toxic or solid  wastes,  materials or
         substances and asbestos,  polychlorinated  biphenyls, urea formaldehyde
         foam,  explosives,  infectious  or  biological  wastes  or  radioactive
         materials.

                  "Knowledge"  of a particular  fact or other matter shall mean,
         as attributed to an  individual,  that (a) such  individual is actually
         aware of such fact or other matter or (b) a prudent individual could be
         expected to discover or  otherwise  become  aware of such fact or other
         matter in the ordinary course of business.

                  "Materially  Adverse Effect", as attributed to the Company and
         the Sellers,  shall mean a materially  adverse  effect on the business,
         financial  condition,  results  of  operation,   prospects,  customers,
         suppliers,  licenses or employee relations, assets or properties of the
         Company or any of its subsidiaries or Affiliates,  and as attributed to
         the Buyer,  shall mean a  materially  adverse  effect on the  business,
         financial  condition,  results  of  operation,   prospects,  customers,
         suppliers,  licenses or employee relations, assets or properties of the
         Buyer or any of its subsidiaries.

                  "Person"  shall mean an  individual,  a  partnership,  a joint
         venture,  a limited  liability  company,  a  corporation,  a trust,  an
         unincorporated organization, a governmental entity or any department or
         agency thereof or any other entity or organization.

                  "Plan"  shall mean any  pension,  retirement,  profit-sharing,
         deferred  compensation,  stock, stock option,  bonus or other incentive
         plan,   any  other   employee   program,   arrangement,   agreement  or
         understanding,  any medical,  vision,  dental or other health plan, any
         life insurance plan, severance plan or any other employee benefit plan,
         including,  without limitation,  any "employee benefit plan" as defined
         in Section 3(3) of ERISA or any Pension Plan or Welfare  Plan, to which
         the  Company or any entity  under  "common  control"  with the  Company
         (within  the meaning of Section  414 of the Code)  contributes  or is a
         party or is bound and under which  current or former  employees  of the
         Company  or any  entity  under  common  control  with the  Company  are
         eligible to participate or derive a benefit.

          "Securities  Act"  shall  mean the  U.S.  Securities  Act of 1933,  as
     amended.

          "Sellers"  shall have the meaning  given that term in the  preamble to
     this Agreement.

                  "Tax" or "Taxes"  shall  mean all  federal,  state,  local and
         foreign income, gross receipts,  excise, import, ad valorem,  property,
         franchise,  license,  sales, use, withholding or other taxes, including
         any deficiency,  penalty,  addition to taxes,  interest,  assessment or
         other charges imposed in connection with a tax.

         Accounting Terms. All accounting terms not specifically defined in this
Agreement  shall be construed in accordance with generally  accepted  accounting
principles ("GAAP") as in effect from time to time, consistently applied.

         Singular and Plural  Forms.  The use herein of the  singular  form also
denotes the plural form,  and the use of the plural form herein also denotes the
singular form, as in each case the context may require.

         Male and Female Forms,  Etc. The use herein of the masculine,  feminine
or  indefinite  forms  shall also  denote the other  forms,  as in each case the
context may require.


<PAGE>

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed as of the date first above written.


BUYER:                               BIORELEASE CORP.


                                     By: /s/ Richard F. Schubert
                                     ---------------------------
                                       Richard F. Schubert, Chairman


REEVES:                               By: /s/ R. Bruce Reeves
- -------                               -----------------------
                                          R. Bruce Reeves


COMPANY:                               THERAMED PARTNERS, INC.


                                        By: /s/ Donald E. Strange
                                        -------------------------
                                           Donald E. Strange, Chairman





SELLERS:                                   /s/ Donald E. Strange
                                           ---------------------
                                           Donald E. Strange

                                           /s/ Paul Leibowitz
                                           ------------------
                                             Paul Leibowitz

                                           /s/ Nigel Fleming
                                           -----------------
                                             Nigel Fleming



<PAGE>




<TABLE>


                                  Schedule 1.1

            Shareholder                       Shares of the Company                  Shares of Buyer
<S>                                           <C>                                    <C>    
 
Donald Strange                                         500                                1,375,000
Nigel Fleming                                          500                                1,375,000
Paul Leibowitz                                         500                                1,375,000
                                                      1500                                4,125,000
<CAPTION>


                                       Options to Purchase Shares of the      Options to Purchase Shares of
           Optionholder                      Company's Common Stock           the Buyer's Common Stock
<S>                                         <C>                                <C>      

R.T. Robertson Consultants                             420                                1,155,000

</TABLE>




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