VANGUARD QUANTITATIVE PORTFOLIOS INC
497, 1996-01-09
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<PAGE>   1

                     VANGUARD QUANTITATIVE PORTFOLIOS, INC.

                             PROSPECTUS SUPPLEMENT

                                JANUARY 10, 1996

The Board of Directors of Vanguard Quantitative Portfolios, Inc. (the "Fund") 
has approved a revised investment advisory agreement with Franklin Portfolio 
Associates ("FPA"), the Fund's investment adviser. The new agreement involves 
a reduction in the annual rate of advisory fees to be paid to FPA.

         Under the terms of the new agreement, the Fund will pay FPA a basic
advisory fee at the end of each fiscal quarter, calculated by applying a
quarterly rate, based on the following annual percentage rates, to the Fund's
average month-end net assets for the quarter:

<TABLE>
<CAPTION>
                 NET ASSETS                                             ANNUAL BASIC FEE RATE
                 ----------------------------------------------------------------------------
                 <S>                                                            <C>
                 First $100 million                                             0.30%

                 Next $650 million                                              0.15

                 Over $750 million                                              0.10

</TABLE>
         Both the current and revised agreements provide that the basic fee may
be increased or decreased by applying an incentive/penalty fee adjustment based
on the investment performance of the Fund relative to the investment record of
the Standard & Poor's 500 Composite Stock Price Index.

         This revised investment advisory agreement replaces the Fund's
existing agreement with the adviser dated October 1, 1987, and will go into
effect on or about April 1, 1996. Until this date, the adviser has agreed to
waive its advisory fees to the extent necessary to abide by the new fee
schedule.


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