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<PAGE> Exhibit 23.1 CONSENT OF INDEPENDENT AUDITORS We consent to the reference to our firm under the captions "Selected Consolidated Financial Data" and "Experts" and to the use of our report dated March 15, 2000, except for Note 13, paragraphs 10 and 11, as to which the date is June 15, 2000, in the Registration Statement on Form S-1 and related Prospectus of CytRx Corporation for the registration of shares of its common stock. /s/ Ernst & Young LLP Atlanta, Georgia June 15, 2000
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