PAREXEL INTERNATIONAL CORP
10-Q, 1999-05-14
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 10-Q


             (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

                                       OR

             ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                  For the Quarterly Period Ended March 31, 1999

                         Commission File Number: 0-27058


                        PAREXEL INTERNATIONAL CORPORATION
             (Exact name of registrant as specified in its Charter)

              Massachusetts                            04-2776269
      (State or other jurisdiction of    (I.R.S. Employer Identification Number)
        incorporation or organization)   


              195 West Street
           Waltham, Massachusetts                                   02451
    (Address of principal executive offices)                       (Zip Code)

Registrant's telephone number, including area code   (781) 487-9900

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days. Yes X No ___

Indicate the number of shares  outstanding  of each of the  issuer's  classes of
common stock, as of the latest  practicable date: As of May 12, 1999, there were
25,102,588 shares of PAREXEL International Corporation common stock outstanding.

<PAGE>



2



                        PAREXEL INTERNATIONAL CORPORATION


                                      INDEX
                                                                           Page

Part I.    Financial Information

Item 1     Financial Statements (Unaudited):

           Condensed  Consolidated  Balance  Sheets--  March 
           31, 1999 and June 30, 1998                                        3

           Condensed Consolidated Statements of Operations -- Three
           months ended March 31, 1999 and 1998;  Nine months ended
           March 31, 1999 and 1998                                           4

           Condensed Consolidated Statements of Cash Flows -- Nine 
           months ended March 31, 1999 and 1998                              5
                        

           Notes to Condensed Consolidated Financial Statements              6

Item 2     Management's Discussion and Analysis of Financial 
           Condition and Results of Operations                               9

           Risk Factors                                                     16
                                                                            
Part II.   Other Information                                                22
                                                                            
Item 2     Changes in Securities and Use of Proceeds                        22
                                                                            
Item 6     Exhibits and Reports on Form 8-K                                 22
                                                                           
Signatures                                                                  24 
                                                      







<PAGE>



                                                             
Part I.  Financial Information
Item 1 - Financial Statements
<TABLE>
                        PAREXEL INTERNATIONAL CORPORATION
                      CONDENSED CONSOLIDATED BALANCE SHEETS
                        (in thousands, except share data)
<CAPTION>

                                                                                      March 31,             June 30,
                                                                                        1999                  1998
                                                                                 --------------------    -----------------
                                                                                       (Unaudited)

<S>                                   ASSETS                                              <C>                 <C>                  
Current assets:
 Cash and cash equivalents                                                                 $46,160             $39,941
                                                                                      
 Marketable securities                                                                      41,293              37,479
 Accounts receivable, net                                                                  136,143             109,741
 Prepaid expenses                                                                           10,404              11,895
 Other current assets                                                                       10,852              10,674
                                                                                 ------------------    ----------------
      Total current assets                                                                 244,852             209,730

Property and equipment, net                                                                 46,057              45,311
Other assets                                                                                15,407               6,717
                                                                                 ==================    ================
                                                                                          $306,316            $261,758
                                                                                 ==================    ================
                    LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities:
 Credit arrangements                                                                       $     -             $ 1,413
 Accounts payable                                                                           16,204              10,923
 Advance billings                                                                           57,501              45,273
 Other current liabilities                                                                  37,020              33,184
                                                                                 ------------------    ----------------
     Total current liabilities                                                             110,725              90,793

Other liabilities                                                                            4,109               2,585
                                                                                 ------------------    ----------------
     Total liabilities                                                                     114,834              93,378
                                                                                 ------------------    ----------------

Stockholders' equity:
 Preferred stock - $0.01 par value; shares
   authorized: 5,000,000; none issued and outstanding                                    -                    -
 Common stock - $0.01 par value; shares authorized:
   50,000,000; shares issued: 25,116,400 and 24,657,637 at
   March 31, 1999 and June 30, 1998, respectively; shares
   outstanding: 25,086,988 and 24,628,225 at March 31, 1999
   and June 30, 1998, respectively                                                             251                 246
 Additional paid-in capital                                                                158,525             149,921
 Retained earnings and cumulative translation adjustment                                    32,706              18,213
                                                                                 ------------------    ----------------
     Total stockholders' equity                                                            191,482             168,380
                                                                                 ==================    ================
                                                                                          $306,316            $261,758
                                                                                 ==================    ================

                                       See  notes  to   condensed   consolidated financial statements.
</TABLE>

<TABLE>



                        PAREXEL INTERNATIONAL CORPORATION
                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (UNAUDITED)
                      (in thousands, except per share data)
<CAPTION>

                                                            For the three months              For the nine months
                                                                ended March 31,                 ended March 31,
                                                            --------------------------------------------------------------
                                                                1999           1998           1999             1998
<S>                                                         ------<C>-----  ----<C>------ -------<C>----  --------<C>---  

Net revenue                                                       $90,032       $73,067       $260,722         $204,051
                                                            --------------  -------------  -------------   -------------
                                                                                           

Costs and expenses:
   Direct costs                                                    59,424        47,364         172,051         132,925
   Selling, general and administrative                             18,398        16,743          52,792          44,054
   Depreciation and amortization                                    4,507         5,241          13,222          11,038
   Acquisition-related charges                                      -             6,173           -              10,273
                                                            --------------  -------------  -------------   -------------
 
                                                                   82,329        75,521         238,065         198,290
                                                            --------------  -------------  -------------   -------------

Income (loss) from operations                                       7,703       (2,454)          22,657           5,761

Other income, net                                                   1,044           905           2,384           2,946
                                                            --------------  -------------  -------------   -------------

Income (loss) before provision for income taxes                     8,747       (1,549)          25,041           8,707

Provision for income taxes                                          3,062           817           8,710           4,827
                                                            --------------  -------------  -------------   -------------

Net income (loss)                                                  $5,685      ($2,366)         $16,331          $3,880
                                                            ==============  =============  =============   =============

Earnings (loss) per common share:
   Basic                                                            $0.23       ($0.10)           $0.66           $0.16
   Diluted                                                          $0.23       ($0.10)           $0.65           $0.16






                                       See  notes  to   condensed   consolidated financial statements.
</TABLE>




<PAGE>
<TABLE>

                        PAREXEL INTERNATIONAL CORPORATION
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (UNAUDITED)
                                 (in thousands)
<CAPTION>

                                                                                                 For the nine months ended
                                                                                                          March 31,
                                                                                           --------------------------------------
                                                                                                   1999                 1998
                                                                                            ----------------    -----------------
<S>                                                                                                <C>                 <C>
Cash flows from operating activities:
  Net income                                                                                       $16,331             $ 3,880
  Adjustments to reconcile net income to net cash
   provided by (used in) operating activities:
    Depreciation and amortization                                                                   13,222              11,038
    Acquisition-related charges                                                                      -                  10,273
    Changes in operating assets and liabilities, net of effects of acquisition                      (7,358)            (20,822)
                                                                                            ----------------    -----------------

Net cash provided by operating activities                                                           22,195               4,369
                                                                                            ----------------    -----------------

Cash flows from investing activities:
  Purchase of marketable securities                                                               (68,840)             (90,217)
  Proceeds from sale of marketable securities                                                      65,026              124,803
  Other investing activities                                                                        -                   (1,377)
  Dividend paid by pooled entity                                                                    -                   (1,293)
  Purchase of plant and equipment                                                                 (13,431)      
  Cash of acquired company                                                                            633              (22,358)
                                                                                                                         -
                                                                                            ----------------    -----------------

  Net cash (used in) provided by investing activities                                             (16,612)               9,558
                                                                                            ----------------    -----------------

Cash flows from financing activities:
  Proceeds from issuance of common stock                                                            3,858                4,453
  Repayments of long-term debt                                                                     (1,386)                (883)
                                                                                            ----------------    -----------------

Net cash provided by financing activities                                                           2,472                3,570
                                                                                            ----------------    -----------------

Elimination of net cash activities of acquired companies
  for duplicated periods                                                                            -                      672
                                                                                            ----------------    -----------------

Effect of exchange rate changes on cash and cash equivalents                                       (1,836)                (167)
                                                                                            ----------------    -----------------

Net increase in cash and cash equivalents                                                           6,219               18,002

Cash and cash equivalents at beginning of period                                                   39,941               36,626
                                                                                            ----------------    -----------------
                                                                                                                     

Cash and cash equivalents at end of period                                                        $46,160              $54,628
                                                                                            ================    =================

                                       See  notes  to   condensed   consolidated financial statements.
</TABLE>

<PAGE>




                        PAREXEL INTERNATIONAL CORPORATION
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                                   (UNAUDITED)

Note 1 -- Basis of Presentation

The  accompanying  unaudited  condensed  consolidated  financial  statements  of
PAREXEL  International   Corporation  (the  "Company")  have  been  prepared  in
accordance with generally accepted  accounting  principles for interim financial
information and with the  instructions of Form 10-Q and Article 10 of Regulation
S-X. Accordingly,  they do not include all of the information and notes required
by generally accepted accounting  principles for complete financial  statements.
In the opinion of management,  all adjustments  (primarily  consisting of normal
recurring  adjustments)  considered  necessary for a fair presentation have been
included.  Operating  results for the three months ended March 31, 1999, are not
necessarily indicative of the results that may be expected for other quarters or
the entire fiscal year. The financial statements for the nine-month period ended
March 31,  1998 have been  restated  to reflect  acquisitions  made in the third
quarter of fiscal  1998  accounted  for under the pooling of  interests  method.
Certain  prior  year  balances  have been  reclassified  in order to  conform to
current year presentation.  For further  information,  refer to the consolidated
financial  statements  and footnotes  thereto  included in the Company's  Annual
Report on Form 10-K for the year ended June 30, 1998.

Note 2 -- Earnings per Share

Effective  December  31,  1997,  the  Company  adopted  Statement  of  Financial
Accounting  Standards No. 128,  "Earnings per Share" ("SFAS 128").  Earnings per
share amounts for prior periods  presented  have been restated to conform to the
SFAS 128  requirements.  The  following  table  outlines  the basic and  diluted
earnings per common share computations (in thousands, except per share data):
<TABLE>
                                                 For the three months ended       For the nine months ended
                                                         March 31,                        March 31,
                                                -----------------------------    ----------------------------
<CAPTION>                                           1999           1998              1999            1998
                                                 ----------    --------------    ------------     ------------
<S>                                                <C>            <C>               <C>             <C> 
Net income (loss) attributable to
     common shares                                  $5,685        ($2,366)          $16,331          $3,880
                                                 ==========    ============     ============    ============


Basic Earnings (Loss) Per Common
  Share Computation:
Weighted average common shares
     outstanding                                    24,834          24,114           24,777          23,846
                                                 ==========    ============     ============    ============
Basic earnings (loss) per common share               $0.23         ($0.10)            $0.66           $0.16
                                                 ==========    ============     ============    ============


Diluted Earnings (Loss) Per Common
  Share Computation:
Weighted average common shares outstanding:
  Shares attributable to common stock               24,834          24,114           24,777          23,846
  Shares attributable to common stock
     options                                           230          -                   328             930
                                                 ----------    ------------     ------------    ------------
                                                    25,064          24,114           25,105          24,776
                                                 ==========    ============     ============    ============
Diluted earnings per common share                    $0.23         ($0.10)            $0.65           $0.16
                                                 ==========    ============     ============    ============

</TABLE>
<PAGE>




Note 3 - Comprehensive Income (Loss)

The Company adopted  Statement of Financial  Accounting  Standards  ("SFAS") No.
130, "Reporting  Comprehensive Income" at the beginning of fiscal 1999. SFAS No.
130 establishes new rules for the reporting and display of comprehensive  income
and its components.  The adoption of SFAS 130 had no impact on the Company's net
income or  stockholders'  equity.  SFAS No. 130 requires the  Company's  foreign
currency  translation  adjustments,   which  prior  to  adoption  were  reported
separately  in  shareholders'  equity,  to be  included  in other  comprehensive
income. Prior year financial statements have been reclassified to conform to the
requirements of this Statement.  Total  comprehensive  income (loss),  which was
comprised of net income (loss) and foreign currency translation adjustments, was
$4.8  million and ($3.9  million)  for the three months ended March 31, 1999 and
1998,  respectively.  Total comprehensive income for the nine months ended March
31, 1999 and 1998 totaled $14.5 million and $3.9 million, respectively.

Note 4 - Acquisition

On March 31, 1999, the Company acquired the stock of Groupe  PharMedicom S.A. in
exchange for  approximately  199,600  shares of the Company's  common stock in a
transaction accounted for as a purchase business combination. Groupe Pharmedicom
is a leading  French  provider of  post-regulatory  services  to  pharmaceutical
manufacturers.  The Company recorded  approximately  $8.5 million related to the
excess cost over the fair value of the net assets acquired. Pro forma results of
operations  of the  Company,  assuming  this  acquisition  was  recorded  at the
beginning  of each period  presented,  would not be  materially  different  from
actual results presented.

Note 5 - New Accounting Pronouncements

In June 1997, the Financial  Accounting Standards Board ("FASB") issued SFAS No.
131 "Disclosures about Segments of an Enterprise and Related  Information." SFAS
No. 131 requires selected  information to be reported on the Company's operating
segments. Operating segments are determined by the way management structures the
segments in making operating decisions and assessing performance. The Company is
currently  reviewing what changes, if any, this will require on the presentation
of the financial statements for fiscal year 1999. The adoption of this statement
will not have an  effect on the  Company's  financial  position  or  results  of
operations but may result in additional disclosures.

In June  1998,  the  FASB  issued  SFAS  No.  133,  "Accounting  for  Derivative
Instruments and Hedging  Activities." SFAS No. 133 establishes new standards for
the  recognition  of gains and losses on  derivative  instruments  and  provides
guidance  as  to  whether  a  derivative  may  be  accounted  for  as a  hedging
instrument. Gains or losses from hedging transactions may be wholly or partially
recorded in earnings or comprehensive income as part of a cumulative translation
adjustment.  Gains or losses on derivative instruments not classified as hedging
instruments  are  recognized  in earnings in the period of change.  SFAS No. 133
will be effective for the Company beginning in fiscal 2000. The Company does not
believe  that  adoption  of SFAS No.  133 will  have a  material  impact  on its
financial position or its results of operations.




Note 6 - Subsequent Event

On April 28, 1999, the Company entered into an Agreement and Plan of Merger with
Covance  Inc.,  ("Covance"),  pursuant  to  which  the  Company  will  become  a
wholly-owned  subsidiary of Covance,  subject to obtaining,  among other things,
applicable stockholder and regulatory approvals. As of the effective date of the
merger,  each outstanding  share of the Company's common stock will be converted
into the  right to  receive  1.184055  shares of common  stock of  Covance.  The
transaction  is expected to be accounted for as a pooling of interests.  Also on
April 28, 1999,  the Company and Covance  entered into  reciprocal  Stock Option
Agreements  under which the  Company  has granted  Covance an option to purchase
19.9% of the  outstanding  shares of the  Company's  common stock at the time of
exercise,  and Covance  has  granted  the  Company an option to purchase  10% of
Covance's  common stock at the time of  exercise,  in each case,  under  certain
circumstances involving the termination of the Agreement and Plan of Merger.


<PAGE>


Item 2.

Management's  Discussion  and  Analysis of  Financial  Condition  and Results of
Operations

The  financial  information  discussed  below  is  derived  from  the  Condensed
Consolidated Financial Statements included herein. The financial information set
forth and  discussed  below is  unaudited  but,  in the  opinion of  management,
reflects all adjustments  (primarily consisting of normal recurring adjustments)
necessary for a fair presentation of such information.  The Company's results of
operations  for a particular  quarter may not be indicative of results  expected
during subsequent fiscal quarters or for the entire year.

The following discussion contains forward-looking  statements that involve risks
and uncertainties.  Such forward-looking statements include those related to the
adequacy of the Company's  existing capital resources and future cash flows from
operations,  the  Company's  Year 2000  readiness  and the  Company's  desire to
continue  to  expand  through  acquisitions.   The  forward-looking   statements
contained  in the  following  discussion  include,  but are not  limited to, any
statements   containing  the  words   "expects,"   "anticipates,"   "estimates,"
"believes," "may," "will," "should" and similar  expressions,  and the negatives
thereof.  The  Company's  actual  experience  may  differ  materially  from that
discussed  in the  forward-looking  statement.  Factors  that might cause such a
difference  include,  but  are not  limited  to,  the  failure  to  successfully
consummate a strategic  acquisition or merger,  including the Company's proposed
merger with  Covance  Inc.,  the failure to achieve  expected  synergies  from a
strategic acquisition or merger, the potential loss or cancellation of, or delay
of work under,  one or more large contracts;  the adequacy and  effectiveness of
the Company's sales force in winning new business; the ability to attract, train
and retain qualified  employees;  the Company's ability to manage adequately its
continued expansion;  the Company's ability to meet its deadlines regarding Year
2000 readiness; and future events that have the effect of reducing the Company's
available   cash  balances  such  as  unexpected   operating   losses,   capital
expenditures or cash expenditures related to possible future  acquisitions;  and
those discussed in Risk Factors.

Overview

The Company is a leading  contract  research  organization.  It provides a broad
range of product  development  services  to  pharmaceutical,  biotechnology  and
medical device companies all over the world. The Company's  primary objective is
to help its clients  obtain  regulatory  approvals for their products and market
those products successfully.  The Company provides the following services to its
clients:

   o clinical trials management; 
   o data management; 
   o biostatistical analysis; 
   o medical  marketing;  
   o clinical  pharmacology;  
   o regulatory  and  medical consulting; 
   o performance improvement;  
   o industry training and publishing; and 
   o other drug development consulting services.

The Company's  contracts are typically  fixed price,  multi-year  contracts that
require  a portion  of the fee to be paid at the time the  contract  is  entered
into,  with the balance of the fee paid in  installments  during the  contract's
duration.  Net revenue from contracts is generally recognized on a percentage of
completion basis as work is performed.

Generally, the Company's contracts are terminable upon sixty days' notice by the
client.  Clients  terminate  or  delay  contracts  for  a  variety  of  reasons,
including,  among others, the failure of products being tested to satisfy safety
requirements,  unexpected  or undesired  clinical  results of the  product,  the
client's decision to forego a particular study,  insufficient patient enrollment
or investigator  recruitment,  or production  problems resulting in shortages of
the drug.

As is customary in the industry,  the Company routinely  subcontracts with third
party  investigators  in connection  with clinical  trials and other third party
service providers for laboratory analysis and other specialized services.  These
and other reimbursable costs, which vary from contract to contract,  are paid by
the client and, in  accordance  with  industry  practice,  are included in gross
revenue.  Reimbursed  costs vary from  contract to  contract.  Accordingly,  the
Company  views net revenue,  which  consists of gross  revenue  less  reimbursed
costs, as its primary measure of revenue growth.

Direct costs primarily  consist of compensation  and related fringe benefits for
project-related  employees,  other  project-related  costs  not  reimbursed  and
allocated  facilities  and  information  systems  costs.  Selling,  general  and
administrative  expenses  primarily  consist of compensation  and related fringe
benefits for selling and  administrative  employees,  professional  services and
advertising  costs,  as  well as  allocated  costs  related  to  facilities  and
information systems.

The  Company's  stock is quoted on the  Nasdaq  Stock  Market  under the  symbol
"PRXL."

Results of Operations

Three Months Ended March 31, 1999 Compared to Three Months Ended March 31, 1998

Net revenue increased by $16.9 million, or 23.1%, to $90.0 million for the three
months ended March 31, 1999 from $73.1  million for the three months ended March
31, 1998.  Growth occurred across each of the Company's  geographic  regions and
each of its major service groups. Net revenue growth was primarily  attributable
to an increase in the volume of projects  serviced by the Company.  There can be
no  assurance  that the Company can sustain this rate of increase in net revenue
from continuing operations in future periods. See "Risk Factors."

Direct costs  increased by $12.0  million,  or 25.3%,  to $59.4  million for the
three months ended March 31, 1999 from $47.4  million for the three months ended
March 31,  1998.  This  increase in direct  costs was  primarily  due to a 23.1%
increase in revenue which required increases in hiring and personnel costs along
with related  facilities  and  information  systems  costs  necessary to support
current and future increased  levels of operation.  Direct costs as a percentage
of net revenue increased to 66.0% for the three months ended March 31, 1999 from
64.8% for the three  months  ended  March 31,  1998,  reflecting  an increase in
overall operational capacity.

Selling,  general and  administrative  expenses  increased by $3.3  million,  or
21.9%,  to $18.4  million for the three  months  ended March 31, 1999 from $15.1
million for the three  months  ended March 31,  1998,  excluding a $1.6  million
noncash charge to adjust accounts  receivable reserves of acquired businesses to
conform  with Company  policy for the three  months  ended March 31, 1998.  This
increase  was  primarily  due  to  increased  personnel,  hiring  expenses,  and
facilities  costs necessary to accommodate the Company's  growth.  Excluding the
noncash charge,  selling,  general and  administrative  expenses  decreased as a
percentage  of net  revenue to 20.4% for the three  months  ended March 31, 1999
from 20.7% for the three months ended March 31, 1998.

Depreciation and amortization  expense  increased by $1.0 million,  or 28.6%, to
$4.5 million for the three months ended March 31, 1999 from $3.5 million for the
three months ended March 31, 1998,  excluding a $1.7 million  noncash  charge to
reflect the reduced service lives of certain  computer  equipment as a result of
integration  activities and the Company's program to upgrade and standardize its
information  technology  platform  during the three months ended March 31, 1998.
This  increase  was  primarily  due  to  an  increase  in  capital  spending  on
information  technology,  facility  improvements  and  furnishings  necessary to
support  the  increased  level of  operations.  Excluding  the  noncash  charge,
depreciation and amortization  expense  increased as a percentage of net revenue
to 5.0% for the three months ended March 31, 1999 from 4.8% for the three months
ended March 31, 1998, reflecting an increase in overall operational capacity.

Income from operations increased $0.7 million, or 10.1%, to $7.7 million for the
three  months  ended March 31, 1999 from $7.0 million for the three months ended
March 31, 1998,  after excluding $9.5 million in  acquisition-related  and other
noncash  charges  incurred for the three months ended March 31, 1998.  Excluding
the impact of these charges, income from operations decreased as a percentage of
net revenue to 8.6% for the three  months ended March 31, 1999 from 9.6% for the
three months ended March 31, 1998, primarily due to the increase in direct costs
noted above.

Other income, net, which is primarily comprised of interest income, increased by
$0.1 million to $1.0 million for the three months ended March 31, 1999 from $0.9
million for the three months ended March 31, 1998.

The Company had an income tax provision of $3.1 million and an effective  income
tax rate of 35% for the three months ended March 31, 1999.  For the three months
ended March 31,  1998,  the Company had an income tax  provision of $0.8 million
despite   a   pre-tax   loss    primarily   due   to   certain    non-deductible
acquisition-related charges. Excluding the effect of such charges, the effective
tax rate for the three months ended March 31, 1998 was 35%.

Results of Operations

Nine Months Ended March 31, 1999 Compared to Nine Months Ended March 31, 1998

Net revenue increased by $56.6 million, or 27.8%, to $260.7 million for the nine
months ended March 31, 1999 from $204.1  million for the nine months ended March
31, 1998.  This net revenue growth was primarily  attributable to an increase in
the volume of projects  serviced by the Company.  There can be no assurance that
the  Company can sustain  this rate of increase in net revenue  from  continuing
operations in future periods. See "Risk Factors."

Direct costs  increased by $39.1  million,  or 29.4%,  to $172.1 million for the
nine months  ended March 31, 1999 from $132.9  million for the nine months ended
March 31,  1998.  This  increase in direct  costs was  primarily  due to a 27.8%
increase in revenues  which  required  increases in hiring and  personnel  costs
along with related facilities and information systems costs necessary to support
current and future  increased  levels of operation.  Direct costs increased as a
percentage of net revenue to 66.0% for the nine months ended March 31, 1999 from
65.1% for the nine  months  ended  March 31,  1998,  reflecting  an  increase in
overall operational capacity.

Selling,  general and  administrative  expenses  increased by $10.3 million,  or
24.2%,  to $52.8  million for the nine months March 31, 1999 from $42.5  million
for the nine months  ended March 31,  1998,  excluding  a $1.6  million  noncash
charge to adjust accounts  receivable reserves of acquired businesses to conform
with Company policy for the nine months ended March 31, 1998.  This increase was
primarily due to increased  personnel,  hiring  expenses,  and facilities  costs
necessary to accommodate  the Company's  growth.  Excluding the noncash  charge,
selling,  general and  administrative  expenses decreased as a percentage of net
revenue to 20.2% for the nine  months  ended  March 31,  1999 from 20.8% for the
nine months ended March 31, 1998.

Depreciation and amortization  expense  increased by $3.9 million,  or 41.9%, to
$13.2 million for the nine months ended March 31, 1999 from $9.3 million for the
nine months ended March 31, 1998,  excluding a $1.7  million  noncash  charge to
reflect the reduced service lives of certain  computer  equipment as a result of
integration  activities and the Company's program to upgrade and standardize its
information technology platform during the nine months ended March 31, 1998. The
increase was  primarily  due to an increase in capital  spending on  information
technology,  facility  improvements  and  furnishings  necessary  to support the
increased level of operations.  Excluding the noncash charge,  depreciation  and
amortization  expense  increased as a percentage  of net revenue to 5.1% for the
nine months  ended March 31, 1999 from 4.6% for the nine months  ended March 31,
1998, primarily due to an increase in assets necessary to support operations.

Income from  operations  increased $3.4 million,  or 17.6%, to $22.7 million for
the nine  months  ended  March 31,  1999 from $19.3  million for the nine months
ended March 31, 1998, excluding $13.6 million in  acquisition-related  and other
noncash  charges for the nine months ended March 31, 1998.  Excluding the impact
of these charges,  income from  operations  decreased to 8.7% of net revenue for
the nine  months  ended  March 31,  1999 from 9.5% of net  revenue  for the nine
months ended March 31, 1998.

Other income, net , which is primarily  comprised of interest income,  decreased
by $0.5  million to $2.4  million for the nine months  ended March 31, 1999 from
$2.9 million for the nine months ended March 31, 1998.  This  decrease  resulted
primarily  from  lower  interest  rates  obtained  due to a shift to  tax-exempt
securities in fiscal 1998, which was partially offset by a shift back to taxable
securities in the third quarter of fiscal 1999.

The  Company  had an income tax  provision  of $8.7  million for the nine months
ended March 31, 1999.  The  effective  income tax rate for the nine months ended
March 31,  1999 was 35%,  compared  to 55% for the nine  months  ended March 31,
1998.  Excluding  the  effect  of  certain  non-deductible   acquisition-related
charges,  the  effective tax rate for the nine months ended March 31, 1998 would
have been 35%.

Liquidity and Capital Resources

Since its  inception,  the  Company  has  financed  its  operations  and growth,
including  acquisition  costs,  with cash flows from operations and the proceeds
from the sale of  equity  securities.  Investing  activities  primarily  reflect
capital   expenditures  for  information  systems   enhancements  and  leasehold
improvements.

The Company's  clinical  research and development  contracts are generally fixed
price, with some variable components, and range in duration from a few months to
several years. The cash flows from contracts typically consist of a down payment
required  at  the  time  the  contract  is  entered  into  and  the  balance  in
installments over the contract's  duration,  usually on a milestone  achievement
basis.  Revenue from the  contracts is generally  recognized  on a percentage of
completion  basis  as work  is  performed.  Accordingly,  cash  receipts  do not
necessarily  correspond to costs  incurred and revenue  recognized on contracts.
The  Company's  operating  cash flow is  influenced  by changes in the levels of
billed and unbilled receivables and advance billings. These account balances and
the number of days' revenue outstanding in accounts  receivable,  net of advance
billings,  can vary based on  contractual  milestones and the timing and size of
cash receipts.  The number of days' revenue outstanding in accounts  receivable,
net of advance  billings,  increased to 59 days at March 31, 1999 compared to 56
days at December 31, 1998.

The Company  had cash and cash  equivalents  of $46.2  million at March 31, 1999
compared to $39.9  million at June 30,  1998.  Net cash  provided  by  operating
activities  of  $22.2  million  resulted  primarily  from net  income  excluding
depreciation and amortization expense of $29.6 million, a $10.8 million increase
in deferred  revenue,  a $5.9 million  increase in accounts  payable and accrued
expenses,  and a $1.6 million  decrease in prepaid  expenses  and other  current
assets, partially offset by a $25.3 million increase in accounts receivable.

Net cash used in investing  activities of $16.6 million  consisted  primarily of
capital  expenditures  of  $13.4  million  related  to  information  technology,
facility  improvements  and  furnishings  along with net purchases of marketable
securities of $3.8 million, partially offset by $0.6 million in net cash from an
acquired business.

Financing  activities  consisted  primarily of net proceeds from the issuance of
common  stock of $3.9  million,  partially  offset  by the  repayment  of credit
arrangements of $1.4 million.

The Company has  domestic  and foreign  line of credit  arrangements  with banks
totaling  approximately  $15.4  million.  At March 31,  1999,  the  Company  had
approximately $15.4 million in available credit under these arrangements.

The  Company's  primary  cash needs are for the payment of  salaries  and fringe
benefits,   hiring  and  recruiting   expenses,   business   development  costs,
acquisition-related  costs, capital expenditures and facility-related  expenses.
The Company  believes that its existing  capital  resources,  together with cash
flows from operations and borrowing capacity under its existing lines of credit,
will be  sufficient  to meet its  foreseeable  cash needs.  In the  future,  the
Company will  continue to consider  acquiring  businesses to enhance its service
offerings,  therapeutic  base, and global  presence.  Any such  acquisitions may
require additional external financing and the Company may from time to time seek
to obtain  funds from public or private  issuance of equity or debt  securities.
There  can be no  assurance  that  such  financing  will be  available  on terms
acceptable to the Company.

Agreement and Plan of Merger

On April 28, 1999, the Company entered into an Agreement and Plan of Merger with
Covance  subject to obtaining,  among other things,  applicable  stockholder and
regulatory  approvals.  As of the effective date of the merger, each outstanding
share of the Company's  common stock will be converted into the right to receive
1.184055  shares of common stock of Covance.  The  transaction is expected to be
accounted for as a pooling of interests. Also on April 28, 1999, the Company and
Covance entered into reciprocal Stock Option  Agreements under which the Company
has granted Covance an option to purchase 19.9% of the outstanding shares of the
Company's  common  stock at the time of  exercise,  and  Covance has granted the
Company  an option to  purchase  10% of  Covance's  common  stock at the time of
exercise, in each case, under certain circumstances involving the termination of
the  Agreement  and  Plan  of  Merger.  There  can  be no  assurance  that  this
transaction  will  be  completed  on time or at all.  Failure  to  complete  the
transaction in a timely manner or at all will have a material  adverse effect on
the Company.

Year 2000  Readiness Disclosure Statement

Information  systems are an integral part of the services the Company  provides.
As such,  the  Company  recognizes  that it must  ensure  that its  service  and
operations  will not be adversely  affected by Year 2000  software and equipment
failures (the "Year 2000 Issue") which can arise from the use of  date-dependent
systems  that  utilize only two digits to  represent  the year  applicable  to a
transaction;  for example,  "99" to represent  "1999"  rather than the full four
digits. Computer systems engineered in this manner may not operate properly when
the last two digits of the year become "00", as will occur on January 1, 2000.

The Company has  initiated a four-phase  program,  led by its Chief  Information
Officer and a global,  cross-functional team, to assess and remediate the effect
of the Year 2000 issue on the Company's operations. As part of this program, the
Company is contacting  its clients,  principal  suppliers,  and other vendors to
assess  whether their Year 2000 issues,  if any,  will affect the Company.  This
effort is ongoing,  with responses  already received from more than 70% of these
entities.

This  Company-wide  effort began in 1997, and to date,  several Year 2000 issues
have  already  been  identified  and  addressed   through  planned  systems  and
infrastructure evolution,  replacement,  or elimination.  The continuing program
described  below was  designed  with the  intent of  ensuring  that the  Company
identifies  and addresses all remaining  Year 2000 issues in advance of the year
2000.

The first phase of the program,  conducting an inventory of all systems that may
be affected  by the Year 2000  issue,  is  complete  for all  critical  business
functions. The second phase of the program, the assessment and categorization of
all the  inventoried  systems by level of priority,  reflecting  their potential
impact on business continuation,  is substantially complete for all key business
areas.  Based on this  prioritization,  the third  phase is to develop  detailed
plans to address each Year 2000 issue, and to develop a general contingency plan
in the event that any critical systems cannot be made fully compliant by January
1, 2000.  Contingency  plans will vary by function  and will  identify  the work
procedure  change or sourcing  alternative  to be utilized in the event that the
primary system fails.  This third phase is currently in progress,  with detailed
plans already completed for most critical business  functions.  The fourth phase
of the program is the  implementation  of the detailed plans. This phase is also
in various  states of completion  within the numerous  functional  areas.  It is
anticipated that all functions  essential for business  continuity will be fully
compliant by June 30, 1999.

The Company  estimates  that the aggregate cost of its Year 2000 program will be
approximately $3 million,  of which approximately 40% has already been incurred.
The Company's  estimates regarding the cost, timing and impact of addressing the
Year 2000 issue are based on numerous  assumptions of future  events,  including
the continued  availability of certain resources,  the ability of the Company to
meet its deadlines and the cooperation of third parties. However, if the Company
cannot continue to utilize certain resources or rely on third parties to respond
timely,  or the Company fails to meet its deadlines  among other things,  actual
results could differ materially from those expected by the Company.

Euro Conversion

On January 4, 1999,  certain member countries of the European Union  established
fixed  conversion  rates  between  their  existing  currencies  and the European
Union's common currency ("Euro").  The transition period for the introduction of
the Euro is from January 4, 1999 to January 1, 2002. The Company has established
a Euro  Initiative  Project Team to  determine  how this will affect the Company
with its business processes,  applications, and internal and external contracts.
The project team has begun the process of determining  the many issues  involved
with the  introduction  of the Euro,  including the  conversion  of  information
technology  systems,  recalculating  currency risk, and impacts on the processes
for preparing taxation and accounting records.

While the Company has not yet completed its full  assessment of the scope of the
Euro Conversion Issue facing its systems and dependencies, based on its analysis
to date it does not  believe  that the costs to be  incurred  will be  material.
However,  until  the full  analysis  is  complete,  the  Company  is  unable  to
definitively determine whether or not future costs will be material.




<PAGE>


RISK FACTORS

In addition to the other information in this report,  the following risk factors
should be  considered  carefully  in  evaluating  the Company and its  business,
including  the  forward-looking  statements  made in the  section of this report
entitled Management's Discussion and Analysis of Financial Condition and Results
of Operations  and other  forward-looking  statements  that the Company may make
from time to time.

THE LOSS OR DELAY  OF  LARGE  CONTRACTS  MAY  NEGATIVELY  IMPACT  THE  COMPANY'S
FINANCIAL PERFORMANCE

Generally,  the Company's clients can terminate their contracts with the Company
upon sixty  days'  notice.  Clients  terminate  or delay their  contracts  for a
variety of reasons, including:

   o products  being tested fail to satisfy  safety  requirements;  
   o products have unexpected or undesired clinical results;
   o the client decides to forego a particular study, perhaps for economic 
     reasons;
   o not enough  patients  enroll in the  study;  
   o not  enough  investigators  are recruited; or 
   o production problems cause shortages of the drug.

In addition,  the Company  believes  that drug  companies may proceed with fewer
clinical trials if they are trying to reduce costs. These factors may cause drug
companies to cancel contracts with contract  research  organizations at a higher
rate  than in the  past.  The loss or delay of a large  contract  or the loss or
delay  of  multiple  contracts  could  have a  material  adverse  effect  on the
Company's financial performance.

THE COMPANY'S  OPERATING RESULTS HAVE FLUCTUATED  BETWEEN QUARTERS AND YEARS AND
MAY CONTINUE TO FLUCTUATE IN THE FUTURE

The  Company's  quarterly  operating  results have varied,  and will continue to
vary. Factors that affect these variations include:

   o the level of new business authorizations in a particular quarter or year;
   o the timing of the  initiation,  progress,  or  cancellation  of significant
     projects;
   o exchange rate fluctuations between quarters or years;
   o the mix of services offered in a particular quarter or year;
   o the timing of the opening of new offices;
   o the timing of other internal expansion costs;
   o the timing and amountof costs associated with integrating acquisitions; and
   o the timing and amount of startup  costs  incurred  in  connection  with the
     introduction of new products and services.

A high  percentage of the Company's  operating costs are fixed.  Therefore,  the
timing of the  completion,  delay or loss of  contracts,  or in the  progress of
client projects, can cause the Company's operating results to vary substantially
between reporting periods.

THE COMPANY  DEPENDS ON A SMALL NUMBER OF INDUSTRIES  AND CLIENTS FOR ALL OF ITS
BUSINESS

The Company depends on research and development  expenditures by  pharmaceutical
and biotechnology  companies.  The Company's  operations could be materially and
adversely affected if:

   o its clients' businesses  experience financial problems or are affected by a
     general economic downturn;
   o consolidation  in the drug or  biotechnology  industries leads to a smaller
     client base for the Company; or
   o its clients reduce their research and development expenditures.

Furthermore,  the Company has benefited to date from the increasing  tendency of
pharmaceutical companies to out-source large clinical research projects. If this
trend slows or  reverses,  the  Company's  operations  would be  materially  and
adversely affected. In fiscal 1998, the Company's five largest clients accounted
for 34% of its  consolidated  net revenue.  For the three months ended March 31,
1999, the Company's five largest clients  accounted for 43% of its  consolidated
net  revenue,  and for the nine months  ended March  31,1999,  the five  largest
clients  accounted  for 42% of  consolidated  net revenue.  In fiscal 1998,  one
client accounted for 12% of consolidated  net revenue,  and for the three months
ended March 31, 1999 a different  client  accounted for 20% of consolidated  net
revenue.  For the nine months ended March 31, 1999, one client accounted for 20%
of consolidated net revenue.  The Company could suffer a material adverse effect
if it lost the business of a significant client.

THE COMPANY'S BUSINESS HAS EXPANDED RAPIDLY AND THE COMPANY MUST PROPERLY MANAGE
THAT EXPANSION

The Company's  business has expanded  substantially,  particularly over the past
few years.  This may  strain  the  Company's  operational,  human and  financial
resources. In order to manage expansion, the Company must:

   o continue to improve its operating, administrative and information systems;
   o accurately  predict its future  personnel and resource needs to meet client
     contract commitments; 
   o track the progress of ongoing client projects; and
   o attract and retain qualified management,  sales,  professional,  scientific
     and technical operating personnel.

THE COMPANY  WILL FACE  ADDITIONAL  RISKS IN EXPANDING  ITS FOREIGN  OPERATIONS.
SPECIFICALLY, THE COMPANY MAY FIND IT DIFFICULT TO:

   o assimilate  differences  in  foreign  business  practices;  
   o hire and retain qualified personnel; and 
   o overcome language barriers.

If an acquired  business does not meet the Company's  performance  expectations,
the Company may have to restructure the acquired business or write-off the value
of some or all of the assets of the acquired  business.  If the Company fails to
properly manage its expansion,  the Company could  experience a material adverse
effect.

THE COMPANY MAY NOT BE ABLE TO MAKE STRATEGIC ACQUISITIONS IN THE FUTURE

The Company relies on it ability to make strategic  acquisitions  to sustain its
growth.  The  Company  has made a number of  acquisitions  and will  continue to
review future acquisition opportunities.  The Company may not be able to acquire
companies on terms and conditions acceptable to the Company.  Additionally,  the
Company  faces  several   obstacles  in  connection  with  the  acquisitions  it
consummates, including:

   o The Company  may  encounter  difficulties  and will  encounter  expenses in
     connection  with the  acquisitions  and the subsequent  assimilation of the
     operations and services or products of the acquired companies;
   o The Company's  management  will  necessarily  divert  attention  from other
     business concerns; and
   o The Company  could lose some or all of the key  employees  of the  acquired
     company.

The Company may also face  additional  risks when acquiring  foreign  companies,
such as  adapting  to  different  business  practices  and  overcoming  language
barriers.  In the event that the operations of an acquired  business do not meet
the Company's performance expectations,  the Company may have to restructure the
acquired  business  or  write-off  the value of some or all of the assets of the
acquired business.  The Company may experience  difficulty  integrating acquired
companies into its operations.

THE COMPANY RELIES ON HIGHLY  QUALIFIED  MANAGEMENT AND TECHNICAL  PERSONNEL WHO
MAY NOT REMAIN WITH THE COMPANY

The  Company  relies  on a  number  of key  executives,  including  Josef H. von
Rickenbach,  its President,  Chief Executive  Officer and Chairman.  The Company
maintains key man life insurance on Mr. von Rickenbach.  The Company has entered
into  agreements  containing   non-competition   restrictions  with  its  senior
officers.  However, the Company does not have employment agreements with most of
its senior  officers and if any of these key  executives  leave the company,  it
could have a material  adverse effect on the Company.  In addition,  in order to
compete  effectively,  the Company must attract and  maintain  qualified  sales,
professional,  scientific and technical  operating  personnel.  Competition  for
these skilled  personnel,  particularly  those with a medical degree, a Ph.D. or
equivalent  degrees is intense.  The Company may not be successful in attracting
or retaining key personnel.

THE COMPANY MAY NOT HAVE ADEQUATE INSURANCE AND MAY HAVE SUBSTANTIAL EXPOSURE TO
PAYMENT OF PERSONAL INJURY CLAIMS

Clinical research services  primarily involve the testing of experimental  drugs
on  consenting  human  volunteers  pursuant to a study  protocol.  Such services
involve  a risk of  liability  for  personal  injury  or death to  patients  who
participate  in the study or who use a drug approved by  regulatory  authorities
after the clinical research has concluded, due to, among other reasons, possible
unforeseen  adverse side effects or improper  administration  of the new drug by
physicians.  In certain cases,  these patients are already seriously ill and are
at risk of further illness or death. The Company's  financial stability could be
materially  and  adversely  affected  if the Company had to pay damages or incur
defense  costs  in  connection  with a claim  that is  outside  the  scope of an
indemnity or insurance coverage. The Company's financial stability could also be
materially  and  adversely  affected  in cases  where  the  indemnity,  although
applicable,  is not performed in accordance  with its terms.  Additionally,  the
Company could be adversely and materially  affected if its liability exceeds the
amount of its  insurance.  The  Company  may not be able to  continue  to secure
insurance on acceptable terms.

THE COMPANY'S STOCK PRICE IS VOLATILE AND COULD DECLINE

The market price of the Company's common stock has fluctuated widely in the past
and may  continue  to do so in the  future  in  response  to  quarter-to-quarter
variations in:

   o operating results;  
   o earnings  estimates by analysts;  
   o market conditions in the industry;
   o prospects  of health  care  reform;  
   o changes in government regulation; and
   o general economic conditions.

In  addition,  the stock  market has from time to time  experienced  significant
price and volume fluctuations that are not related to the operating  performance
of particular  companies.  These market  fluctuations  may adversely  affect the
market price of the  Company's  common stock.  Since the Company's  common stock
currently trades at a relatively high  price-earnings  multiple,  due in part to
analysts'  expectations  of continued  earnings  growth,  the price of the stock
could quickly and  substantially  decline as a result of even a relatively small
shortfall in earnings from, or a change in, analysts' expectations. Investors in
the Company's common stock must be willing to bear the risk of such fluctuations
in earnings and stock price.

THE  COMPANY'S   BUSINESS  DEPENDS  ON  CONTINUED   COMPREHENSIVE   GOVERNMENTAL
REGULATION OF THE DRUG DEVELOPMENT PROCESS

In the United States,  governmental  regulation of the drug development  process
has become  more  complicated  and more  extensive.  However,  the FDA  recently
announced  regulatory  changes  intended to streamline the approval  process for
biotechnology   products  by  applying  the  same   standards  for  approval  of
biotechnology  products  as are in effect  for  conventional  drugs.  In Europe,
governmental  authorities are coordinating common standards for clinical testing
of new drugs, leading to changes in the various  requirements  currently imposed
by each country.  In April 1997,  Japan  legislated good clinical  practices and
legitimatized the use of contract research organizations. The Company's business
could  be  materially  and  adversely  affected  if  governments  relaxed  their
regulatory requirements or simplified their drug approval procedures, since such
actions  would  eliminate  much of the demand  for the  Company's  services.  In
addition,  if the Company was unable to comply with any  applicable  regulation,
the  relevant  governmental  agencies  could  terminate  the  Company's  ongoing
research or disqualify research data.

THE COMPANY FACES INTENSE COMPETITION

The Company primarily  competes against in-house  departments of drug companies,
full  service  contract  research   organizations,   and  to  a  lesser  extent,
universities,  teaching  hospitals and other site  organizations.  Some of these
competitors  have  greater  capital,  technical  and  other  resources  than the
Company. Contract research organizations generally compete on the basis of:

   o previous experience;
   o medical and scientific  expertise in specific therapeutic areas; 
   o the quality of services;
   o the ability to organize and manage large-scale trials on a global basis;
   o the  ability to manage  large and  complex  medical  databases;  
   o the ability to provide statistical and regulatory services;
   o the ability to recruit investigators and patients;
   o the ability to integrate information technology with systems to improve the
     efficiency of contract research;
   o an international presence with strategically located facilities;
   o financial strength and stability; and 
   o price.

The contract research organizations industry is fragmented, with several hundred
small,  limited-service  providers  and  several  large,  full-service  contract
research  organizations  with global  operations.  The Company  competes against
large  contract  research   organizations,   including  Quintiles  Transnational
Corporation,  Covance Inc., and Pharmaceutical  Product  Development,  Inc., for
both clients and acquisition  candidates.  In addition, the Company competes for
contract  research  organizations  contracts  as a result  of the  consolidation
within the drug  industry  and the  growing  tendency of drug  companies  to out
source to a small number of preferred contract research organizations.

THE COMPANY MAY LOSE BUSINESS OPPORTUNITIES AS A RESULT OF HEALTH CARE REFORM

Numerous  governments  have  undertaken  efforts to control  growing health care
costs through legislation, regulation and voluntary agreements with medical care
providers  and drug  companies.  In the last few years,  the U.S.  Congress  has
entertained several  comprehensive  health care reform proposals.  The proposals
were  generally  intended to expand  health care  coverage for the uninsured and
reduce the growth of total health care expenditures. While the U.S. Congress did
not adopt any of the proposals,  members of Congress may raise similar proposals
in the future. If any of these proposals are approved by the U.S. Congress, drug
and  biotechnology  companies  may  react  by  spending  less  on  research  and
development.  If this were to occur,  the  Company  would  have  fewer  business
opportunities.  The Company is unable to predict the likelihood that health care
reform  proposals will be enacted into law or the effect such laws would have on
the Company's business.

Many governments  outside the U.S. have also reviewed or undertaken  health care
reform. The Company cannot predict the impact that any pending or future foreign
health care reform proposals may have on its business in other countries.

THE COMPANY IS SUBJECT TO CURRENCY TRANSLATION RISKS

The Company  derived  approximately  41% of its net revenue for fiscal 1998, 40%
for the three  months  ended March 31,  1999,  and 42% for the nine months ended
March 31, 1999 from operations outside of North America.  The Company's revenues
and  expenses  from  foreign   operations  are  usually   denominated  in  local
currencies.  The  Company is  therefore  subject to exchange  rate  fluctuations
between local  currencies and the United States  dollar.  To the extent that the
Company  cannot  shift this  currency  translation  risk to other  parties,  the
Company's  operating  results could be materially  and adversely  affected.  The
Company does not currently hedge against the risk of exchange rate fluctuations.

A THIRD PARTY MAY HAVE DIFFICULTY ACQUIRING THE COMPANY

Certain  provisions  of the  Company's  Restated  Articles of  Organization,  as
amended, and Restated By-Laws contain provisions that make it more difficult for
a third party to acquire,  or may discourage a third party from  acquiring,  the
Company.  These provisions could limit the price that certain investors might be
willing  to pay in the  future  for shares of the  Company's  common  stock.  In
addition, the Board of Directors of the Company may issue preferred stock in the
future  without  further  stockholder  approval.  The Board of  Directors of the
Company  would  determine  the  terms  and  conditions,  as well as the  rights,
privileges and preferences of such preferred  stock. The holders of common stock
would be subject to, and may be adversely affected by, the rights of any holders
of preferred  stock that the Board of  Directors  of the Company may issue.  The
Company  benefits  from its Board of  Directors'  ability to issue the preferred
stock by affording the Company desirable flexibility in connection with possible
acquisitions  and other  corporate  purposes.  However,  the Company's  Board of
Directors'  ability to issue the preferred stock could also adversely affect the
market  price of the  common  stock and could  have the effect of making it more
difficult  for a third  party to  acquire,  or  discouraging  a third party from
acquiring a majority of the outstanding voting stock of the Company. The Company
has no present plans to issue any shares of preferred stock.







<PAGE>


Part II.  Other Information

Item 2.   Changes in Securities and Use of Proceeds

          a) Not applicable
          b) Not applicable
          c) Effective  March 31, 1999, the Company issued 199,568 shares of its
             common stock,  par value $.01 per share,  in  consideration  of the
             acquisition  all  of  the  outstanding   share  capital  of  Groupe
             PharMedicom  S.A.  ("PharMedicom").  All of such shares were issued
             without  registration under the Securities Act of 1933, in reliance
             on the exemption from  registration  provided by Regulation S under
             such Act. The shares were offered,  sold and delivered  only to the
             shareholders  of PharMedicom,  all of whom were  non-United  States
             persons,   outside  of  the  United  States,  its  territories  and
             possessions.

Item 6.   Exhibits and Reports on Form 8-K

          (a)Exhibit No.      Description

              2.1             Agreement and Plan of Merger dated as of April 28,
                              1999 among  Covance Inc.,  CCJ Holding  Corp.  and
                              PAREXEL  International  Corporation  (incorporated
                              herein  by   reference   to  Exhibit  2.1  to  the
                              Company's  Current  Report on Form 8-K dated April
                              28, 1999 and filed with the  Commission  on May 4,
                              1999).

             2.2              Share Acquisition Agreement with respect to Groupe
                              PharMedicom S.A., dated March 31, 1999 among Herve
                              Laurent,  Philippe Conquet and Others, as Sellers,
                              and PAREXEL International Corporation, as Buyer.

             4.1              Registration  Rights  Agreement  dated as of March
                              31, 1999 among PAREXEL  International  Corporation
                              and   certain   former   stockholders   of  Groupe
                              PharMedicom S.A.

             99.1             Stock Option  Agreement dated April 28, 1999 among
                              Covance Inc., as grantee and PAREXEL International
                              Corporation,  as  issuer  (incorporated  herein by
                              reference to Exhibit 99.1 to the Company's Current
                              Report on Form 8-K dated  April 28, 1999 and filed
                              with the Commission on May 4, 1999).

             99.2             Stock Option  Agreement dated April 28, 1999 among
                              PAREXEL International Corporation,  as grantee and
                              Covance  Inc., as issuer  (incorporated  herein by
                              reference to Exhibit 99.2 to the Company's Current
                              Report on Form 8-K dated  April 28, 1999 and filed
                              with the Commission on May 4, 1999).

             27               Financial Data Schedule




          (b) Reports on Form 8-K.

              The Company  filed a Current  Report on Form 8-K dated January 27,
              1999 reporting the public announcement of its quarterly earnings.


<PAGE>



                                   SIGNATURES


Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized, on this 14th day of May, 1999.


 PAREXEL International Corporation


 By:/s/   Josef H. von Rickenbach__________

       Josef H. von Rickenbach
       President, Chief Executive Officer and Chairman




 By:/s/   William T. Sobo, Jr. ______________

      William T. Sobo, Jr.
      Senior Vice President, Chief Financial Officer

<PAGE>
EXHIBIT 2.2
DATED  31 March 1999






                           SHARE ACQUISITION AGREEMENT


                 HERVE LAURENT, PHILIPPE CONQUET AND OTHERS (1)

                      PAREXEL INTERNATIONAL CORPORATION (2)






























                                       l-g

                           190 STRAND, LONDON WC2R 1JN
                      TEL: 0171 379 0000 FAX: 0171 379 6854
                               Ref: RWE/0892677.01

 1 -

             
<TABLE>
892677.01

                                    CONTENTS
<CAPTION>
<S>         <C>                                                                                         <C>
No           Heading                                                                                     Page

1.           Definitions                                                                                    1

2.           The Shares                                                                                     9

3.           Repayment by Sellers and the Company                                                           9

4.           Completion                                                                                     9

5.           vendors Warranties                                                                            11

6.           COMPLIANCE WITH US LAW                                                                        15

7.           Restrictive Covenants                                                                         18

8.           Pension Scheme                                                                                19

9.           General Provisions                                                                            19

10.          Announcements                                                                                 20

11.          Costs                                                                                         20

12.          Notices                                                                                       20

13.          Governing Law and Jurisdiction                                                                21



THE FIRST SCHEDULE:  Particulars of the Sellers                                                            22

THE SECOND SCHEDULE:  Basic Information concerning the Company                                             23

THE THIRD SCHEDULE:  Particulars of Subsidiaries                                                           24

THE FOURTH SCHEDULE:  Property                                                                             25

THE FIFTH SCHEDULE:  Provisions affecting the Pension Scheme                                               26

THE SIXTH SCHEDULE:  VENDOR'S Warranties                                                                   27

THE SEVENTH SCHEDULE:  limits on claims                                                                    45

THE EIGHTH SCHEDULE:  holdback                                                                             47

THE NINTH SCHEDULE: SPECIFIC CONTINGENCIES                                                                 50


Affiliate Agreement: Appendix A
Registration Rights Agreement: Appendix B


                                      - 3 -

892677.01


 

892677.01

THIS AGREEMENT is made the 31st day of March 1999

BETWEEN:

(1)          THE SEVERAL PERSONS whose names and addresses are set out in Column
             (1) of the First Schedule hereto ("the Sellers") and

(2)          PAREXEL   INTERNATIONAL   CORPORATION  (whose  principal  place  of
             business is at 195 West Street, Waltham,
             Massachusetts 02154, USA ("the Purchaser")

WHEREAS

(A)          Groupe PharMedicom  (registered No. B411470481) ("the Company") has
             an authorised and issued share capital particulars whereof together
             with other details are set out in the Second Schedule hereto.

(B)          The Sellers are the  beneficial  owners of or are otherwise able to
             procure  the  transfer  of the  numbers  of shares  of the  Company
             specified in Column (2) of the First Schedule hereto opposite their
             respective names such numbers of shares together comprising all the
             issued shares of the Company.

(C)          The Sellers are desirous of selling and the Purchaser is willing to
             acquire  the  Shares  (as  hereinafter  defined)  on the  terms and
             subject to the conditions hereinafter contained.

(D)          Particulars  of  the  companies   which  at  the  date  hereof  are
             subsidiaries of the Company are set out in the Third Schedule.

NOW IT IS HEREBY AGREED as follows:-

1.           Definitions

1.1          In  this   Agreement  and  the   Schedules   hereto  the  following
             expressions  shall unless the context  otherwise  requires have the
             meanings following:-

"the  Accounts"  the  unaudited  balance  sheet as at the 31  December  1998 and
   unaudited  profit and loss  account for the 9 months ended on the 31 December
   1998 of each of the Company and the Subsidiaries including in the case of the
   Company  the  unaudited  consolidated  balance  sheet as at such date and the
   unaudited  consolidated  profit and loss  account for such period and in each
   case the directors report and notes in relation thereto; US GAAP Accounts the
   Accounts and the related  consolidated  statement  of earnings,  shareholders
   equity and cash flows restated to USGAAP;

"Accounts  Reliefs" means any Reliefs where the  availability of the Reliefs has
   been shown as an asset in the  Accounts  or has been  taken  into  account in
   computing (and so reducing) any provision for deferred taxation which appears
   in the Accounts or has resulted in no provision for deferred  taxation  being
   shown in the Accounts;

"Affiliate  Agreements"  the  agreements in the form annexed  hereto at Appendix
   A;

"the Balance Sheet Date" 31 December 1998;

"Business"  the  business(es)  of  statistical  studies,  clinical,  biological,
   epidemiological  studies,  creation and  marketing of software,  consultancy,
   information and documentation, and marketing services on pharmaceutical areas
   carried on by the Group at the date hereof;

"Business  day" a day on which  banks  shall be open in Paris for the conduct of
   general banking business (excluding Saturdays);

"Tax Claim" shall mean any claim,  assessment,  notice,  demand  letter or other
   document  issued or action  taken by or on behalf of any  Taxation  Authority
   whereby it appears that any member of the Group or the  Purchaser is to be or
   is sought to be made subject to a Liability to Taxation;

"the Consideration Shares" 199,746 Common Stock of US$0.01 each of the Purchaser
   (ranking  pari  passu  with the  Common  Stock of the  Purchaser  in issue at
   Completion and credited as fully paid);

"Completion"   completion  of  the  obligations  of  the  parties  hereunder  in
   accordance with the provisions of Clause 4 hereof;

"the Disclosure Letter" the letter of even date herewith from the Sellers to the
   Purchaser  a copy of which is  annexed  hereto;  

"Encumbrance" includes any interest or equity of any person (including,  without
   prejudice to the generality of the foregoing, any right to acquire, option or
   right of pre-emption),  or any mortgage,  charge,  pledge, lien,  assignment,
   hypothecation,  security  interest,  title  retention  or any other  security
   agreement or arrangement;

"Event" includes (without limitation) any act omission, transaction or shortfall
   in distributions  whether or not a member of the Group is a party thereto and
   includes Completion;

"Group" the Company together with the Subsidiaries;

"Senior Commercial Counsel/ Independent  Accountant" means such person who shall
   be nominated by either party upon agreement or failing agreement within three
   days by the  President  of the  Commercial  Court of Paris for the time being
   following request by any party;  "Industrial Property Rights" patents,  trade
   marks,  registered  designs,  pending  applications for any of the foregoing,
   trade or business names and copyright and design rights;

"Liability to  Taxation"  a  liability  to make an actual  payment  of  Taxation
   whether or not such Taxation is also or alternatively  chargeable  against or
   attributable  to any other  person and whether or not any member of the Group
   shall or may have any right of  recovery or  reimbursement  against any other
   person;

"March Accounts"  the unaudited and projected  Balance Sheet and Profit and Loss
   Accounts for the Group for the period January, February and March 1999;

"Nasdaq" National  Association of Securities  Dealers,  Inc. Automated Quotation
   System;

"New Reliefs" any Reliefs which arise to the Company or any of the Subsidiaries:

   (a) as a result of any Event occurring after the Balance Sheet Date; or

   (b) in respect of any period commencing on or after the Balance Sheet Date;

"Proceeding" any judicial or  quasi-judicial  process or other  investigation by
   any court, government department, regulator or otherwise;

"the Property" the property or properties short particulars  whereof are set out
   in the Fourth Schedule hereto and includes any part or parts thereof together
   with any property  used by any member of the Group and a place of business in
   any Relevant Country;

"the Purchaser's Lawyers" Lawrence Graham;

"Registration Rights Agreement"  agreement in the approved terms between certain
   of the parties  hereto to be entered into at Completion  attached as appendix
   "B"- hereto;  "Relevant Country" means any country in which any member of the
   Group has a place of  business,  including,  but not  limited  to the  United
   Kingdom, the United States of America , Germany and France;

"Reliefs" means all amounts  available to reduce either  profits or Taxation and
   includes  (without  limitations) all losses  allowances  exemptions  set-offs
   deductions credits and repayments;

"SEC" the United States Securities and Exchange Commission;

"the Service  Agreements"  the  service  agreements  between  the Company and H.
   Laurent, the Company and P. Conquet;

"the Shares"  the  shares of the  Company  specified  in Column (2) of the First
   Schedule hereto;

"Taxation" means:-

   (a)any charge,  tax,  duty,  levy or  liability  imposed by national or local
      government or any other person  pursuant to any relevant law or equivalent
      legislation in any country  including  orders,  regulations,  instruments,
      bye-laws or other  subordinate  legislation made under the relevant law or
      equivalent  legislation in any country and includes  (without  limitation)
      corporation  tax, income tax,  capital gains tax, value added tax, customs
      and other import duties, social  contributions,  stamp duty, capital duty,
      capital  transfer tax and  inheritance tax and any amount which any member
      of the Group is liable to account for by way of deduction or  withholding,
      amounts equivalent to the foregoing and any payment whatsoever  chargeable
      in any  country  which any  member of the Group may be or become  bound to
      make to any person as a result of the operation of any enactment  relating
      to Taxation;

   (b)any  penalties  fines  costs  charges   interest  or  damages  payable  in
      connection with any Taxation;

   (c)any payment made or liability  incurred in connection  with any reasonable
      settlement of any Tax Claim;

   (d)all costs and expenses  reasonably  incurred by any member of the Group or
      the Purchaser in connection with any Tax Claim;

"Taxation  Authority"  any  national  or  local  government,  authority  or body
   whatsoever  whether of a Relevant  Country or  elsewhere  empowered to impose
   collect or administer Taxation;

"Seller Representative" means either of H. Laurent or P. Conquet;

"the Sellers' lawyer" Maitre Denis Polack;

"Sellers Warranties" those  representations and warranties made to the Purchaser
   contained or referred to in Clauses 5 and 6 and the Sixth Schedule hereto;

"US Person" any natural person resident in the United States;

   any partnership or  corporation  organised or  incorporated  under the laws of
      the United States;

   any estate of which any executor or administrator is a US person;

   any trust of which any trustee is a US person;

   any agency or branch of a foreign entity located in the United States;

   any non-discretionary  account or  similar  account  (other  than an estate or
      trust) held by a dealer or other fiduciary for the benefit or account of a
      US person;

   any discretionary  account or similar  account (other than an estate or 
      trust) held by a dealer or other fiduciary organised, incorporated, or (if
      an individual) resident in the United States; and

   any partnership or corporation if:

      (a) organised or incorporated under the laws of any foreign  jurisdiction;
          and

      (b) formed by a US person  principally  for the  purpose of  investing  in
          securities  not registered  under the United States  Securities Act of
          1933, as amended (the "Act"),  unless it is organised or  incorporated
          and owned by accredited investors (as defined in Rule 501(a) under the
          Act) who are not natural persons, estates or trusts.

"Year 2000  compliant"  means that the performance or  functionality  of Systems
   used or required by the Group for the  purposes of its  business  will not be
   affected by dates prior to, during or after the Year 2000,  whether through a
   failure  of a  System  to  adequately  recognise  or  process  such  dates or
   otherwise and a "System" is any relevant computer system including  hardware,
   equipment with embedded computer chips,  software,  networks,  interfaces and
   data storage.

1.2          References to the  consequences  of acts or  transactions  effected
             prior to  Completion  shall  include the combined  effect of two or
             more acts or transactions the first of which shall have taken place
             or be  deemed  to  have  taken  place  on or  before  the  date  of
             Completion.  Reference  to  the  result  of  Events  on  or  before
             Completion  shall include the combined result of two or more Events
             the  first of which  shall  have  taken  place or is deemed to have
             taken place on or before Completion.

1.3          The expression  "the Sellers"  includes their  respective  personal
             representatives.

1.4          Any document  expressed  to be "in the  approved  terms" means in a
             form approved and for the purpose of identification signed by or on
             behalf of the parties hereto.

1.5          Where any  Warranty or matter  disclosed in the  Disclosure  Letter
             refers  to the  knowledge  information  awareness  or  belief  of a
             Seller,  each of the  Sellers  shall  be  deemed  to have  made all
             reasonable  enquiries  into the subject  matter of that Warranty or
             Disclosure.

1.6          The expression  "Subsidiary"  shall mean any subsidiary (as defined
             by  Article  354 of the French  Law on  Companies  (the Act of July
             1966)) for the time being of the Company.

1.7          The  expression  "the Company"  where used in clauses 3, 4, 5 and 6
             and in the Sixth and Seventh Schedules to this Agreement shall mean
             each of the Company and each of its Subsidiaries.

1.8          References to Clauses,  Sub-clauses and Schedules are references to
             Clauses and Sub-clauses of this
             Agreement and Schedules to this Agreement.

1.9          In this  Agreement  and the Schedules  hereto the masculine  gender
             shall  include the feminine and neuter,  the singular  number shall
             include the plural and vice versa,  and references to persons shall
             include   bodies   corporate,   unincorporated   associations   and
             partnerships.

1.10         References in this Agreement to any law shall include (except where
             the  context  otherwise  requires)  any law  which  amends  extends
             consolidates  or  replaces  the  same  and any law  which  has been
             amended,  extended,  consolidated or replaced by the same and shall
             include  any order,  regulation,  instrument  or other  subordinate
             legislation  made under the  relevant  law except  where and to the
             extent that any liability of the Sellers under this Agreement would
             be created or  extended  as a result of any  amendment,  extension,
             consolidation or replacement of any law in force at Completion.

1.11         The headings in this  Agreement are inserted for  convenience  only
             and shall not affect the
             construction hereof.

2.           The Shares

2.1          The Sellers shall sell and the Purchaser  shall acquire with effect
             from  Completion the Shares free from any  Encumbrance and together
             with  all  accrued  benefits  and  rights  for  the   consideration
             described in sub-clause 2.2 below ("the Consideration").

2.2          The  Consideration  shall be satisfied by the  allotment  and issue
             (subject   to   sub-clause   2.3  below)  to  the  Sellers  of  the
             Consideration Shares in the amounts set against each of their names
             in column 4 of the First Schedule.

2.3          A proportion of the  Consideration  Shares determined in accordance
             with the Eighth and Ninth  Schedules  shall not be delivered to the
             Sellers on Completion but shall be withheld by the Purchaser on the
             terms and conditions set out in the Eighth and Ninth Schedules.

3.           Repayment by Sellers and the Company

             The Sellers will prior to or  simultaneously  with Completion repay
             to the Company any sums due by the  Sellers,  any  Associate of the
             Sellers  or any of them (or by any  person  to whom  they or any of
             them are or is a trustee or personal representative) to the Company
             at Completion and shall at Completion procure that neither they nor
             any such  person  as  aforesaid  has any  claim or right of  action
             against the Company (other than in respect of current  remuneration
             as  directors  or  executives  or sums  expressly  disclosed in the
             Disclosure  Letter)  and that the Company is not in any way obliged
             or indebted  (other than as  aforesaid)  to them or any such person
             and at  Completion  the  Sellers  will  confirm  in  writing to the
             Purchaser that they have so procured.

4.           Completion

4.1          Completion shall take place on March 31, 1999 at the offices of the
             Purchaser's  Lawyers  or such  other  offices  as the  parties  may
             subsequently agree when:-

4.1.1        the  Sellers  shall  deliver  or  cause  to  be  delivered  to  the
             Purchaser:-

             (a)  duly executed transfers in respect of the Shares;

             (b)  registers  of the  Company  made up to the date of  Completion
                  etc;



             (c)  if the  Purchaser so requires an  effective  waiver by each of
                  the  members of the  Company  of any rights  which he may have
                  under the articles of association and by-laws (statuts) of the
                  Company to have the  Shares or any of them  offered to him for
                  purchase and any other documents necessary to substantiate the
                  right  of the  transferors  of the  Shares  pursuant  to  this
                  Agreement to transfer the same;

             (d)  written confirmation pursuant to Clause 3; and

             (e)  written  resignation  letters by such of the  directors of the
                  Company and the Subsidiaries as the Purchaser may nominate (if
                  any), each such letter  incorporating an acknowledgement  that
                  the party  resigning has no claims  (whether for  compensation
                  for  loss of  office  or  termination  of  employment,  unpaid
                  remuneration  or otherwise  howsoever)  against the Company or
                  any of the Subsidiaries;

             (f)  representation   letters   from  certain  of  the  Sellers  to
                  Pricewaterhouse  Coopers L.L.P that the transaction  qualifies
                  for  pooling of  interests  accounting  treatment;  (g) signed
                  stock transfer forms in favour of the Purchaser in relation to
                  the Holdback Shares and Additional Holdback Shares;

             (h)  duly  executed  Affiliate  Agreements  by H.  Laurent  and  P.
                  Conquet and Comir.

4.1.2        the Sellers shall  procure that the Directors  shall hold a meeting
             of the Directors of the Company at which

             (a)  the Directors  shall appoint such persons as the Purchaser may
                  nominate  as   directors   of  the  Company  and  procure  the
                  resignation  without  compensation of any nature whatsoever of
                  such of the  Directors  and  Secretary  of the  Company as the
                  Purchaser may nominate;

             (b)  the Directors shall vote in favour of the  registration of the
                  Purchaser or its nominees as members of the Company;



             (c)  the Directors shall approve the Service Agreements;

4.1.3        the  Sellers  shall  procure  that the  Company  will and the other
             persons and parties thereto shall enter into the Service Agreements
             and the Affiliate Agreements;

4.1.4        Subject to the  performance by the Sellers of their  obligations in
             accordance  with  the  foregoing  provisions  of this  Clause 4 and
             subject to the  provisions of Clause 2.3 the Purchaser  shall allot
             to each of the Sellers the number of Consideration  Shares to which
             he is entitled hereunder and deliver  certificates  evidencing such
             Consideration Shares to the Sellers; and

4.1.5        each  of the  parties  will  enter  into  the  Registration  Rights
             Agreement.

4.2          If in any respect the provisions of sub-clauses 4.1.1, 4.1.2, 4.1.3
             and 4.1.5 are not complied with on the date for  Completion  set by
             clause 4.1 the Purchaser may:-

4.2.1        defer Completion to a date not more than 28 days after the date set
             out above  (and so that the  provisions  of this  sub-clause  shall
             apply to Completion as so deferred); or

4.2.2        proceed to Completion so far as practicable  (without  prejudice to
             its rights hereunder).

4.3          If in any  respect  the  provisions  of  sub-clause  4.1.4  are not
             complied  with on the date for  Completion  set by Clause 4.1,  the
             Sellers may:-

4.3.1        defer Completion to a date not more than 28 days after the date set
             out above  (and so that the  provisions  of this  sub-clause  shall
             apply to Completion as so deferred); or

4.3.2        proceed to Completion so far as practicable  (without  prejudice to
             its rights hereunder).

5.           vendors Warranties

5.1          The Sellers  hereby  warrant and  represent to the Purchaser in the
             terms of the Sellers Warranties.

5.2          In particular and without prejudice to the generality of sub-clause
             5.1 the Sellers  hereby warrant and represent to the Purchaser that
             the recitals to this  Agreement and the Sellers  Warranties  are at
             the date hereof true and accurate in all respects.

5.3          The  Sellers  Warranties  shall  apply  (mutatis  mutandis)  to the
             Company and to the  Subsidiaries  and any  references  in the Sixth
             Schedule or elsewhere in this Agreement to any statutory provision,
             regulation  or  accounting  principles  applying in France shall be
             deemed  to  include   references  to  any   equivalent   provision,
             regulation or accounting principles in any Relevant Country and any
             references  to any  governmental  or  administrative  authority  or
             agency shall include  references to any equivalent  governmental or
             administrative authority or agency in any Relevant Country.

5.4          The Purchaser  shall not be entitled to claim that any fact renders
             any of the Sellers  Warranties  untrue or misleading or caused them
             to  be  breached  if it  has  been  fully,  fairly  and  accurately
             disclosed to the Purchaser in the Sellers' Disclosure Letter.

5.5          The Sellers hereby covenant and undertake to the Purchaser that, if
             after the date hereof it shall be found that any matter the subject
             of a Sellers  Warranty was not as warranted  then,  notwithstanding
             any further  right of the  Purchaser  hereunder  in respect of such
             breach of Sellers Warranty, if the effect thereof is that:-

5.5.1        the value of the Group is less than its value  would  have been had
             there been no breach of Sellers Warranty; or

5.5.2        the  value of any  asset  belonging  to the  Group is less than its
             value would have been had there been no breach of Sellers Warranty;
             or

5.5.3        any asset represented as belonging to the Group does not so belong;
             or

5.5.4        the Group is subject to any liability  (including  any Liability to
             Taxation)  not  disclosed  (in  accordance  with Clause 5.4) in the
             Disclosure Letter; or

5.5.5        the Company has incurred or is under any  liability  or  contingent
             liability  which it would not have incurred or been under had there
             been no breach of Sellers Warranty;

             then the Sellers shall on demand account to the Purchaser  pursuant
             to the provisions of the Eighth Schedule for an amount equal to the
             amount  of  any  loss  or  reduction  in  value  or  liability  (or
             contingent  liability)  so  incurred  by  the  Purchaser  or by any
             company in the Group and any such  settlement  made by the  Sellers
             shall be  taken  into  account  in  assessing  the  damages  of the
             Purchaser in connection with,  arising out of or resulting from any
             such breach of Sellers Warranty.

5.6          To the  extent  not  already  provided  for in Clause 5.5 above the
             Sellers  hereby  agree to provide to the  Purchaser an amount equal
             to:-

5.6.1        any Liability to Taxation of the Group:

             (a)  arising as a  consequence  of or by  reference  to one or more
                  Events which occurred on or before the date hereof; or

             (b)  arising in respect of or by reference  to any income,  profits
                  or gains which were  earned,  accrued or received on or before
                  or in respect of a period ended on or before the date hereof;

5.6.2        any  Liability to Taxation  which would have arisen (and in respect
             of which the Sellers would have been liable under Clause 5.6.1) but
             for the setting off of an Accounts  Relief or a New Relief  against
             that  Liability  to  Taxation  or (as the case may be)  against the
             income  profits  or  gains  which  would  have  given  rise to that
             Liability to Taxation;

5.6.3        any Liability to Taxation  which would (on the basis of the current
             rates of Taxation and assuming  income profits or gains  chargeable
             to Taxation of an amount  equal to the Relief)  have been saved but
             for the loss of any Accounts Relief;

5.6.4        any  reasonable  costs and expenses  incurred in connection  either
             with any such  liability  or amount as is  referred  to in  Clauses
             5.6.1 to 5.6.3  inclusive or with any Tax Claim in respect  thereof
             (including  investigating,  assessing or contesting the same) or in
             taking or defending  any action under this  schedule at the request
             or direction of the Sellers.

5.6.5        The  Indemnities  contained  in  Clause  5.6 above do not cover any
             Liability to Taxation:-

             (a)  to the  extent  that  provision  or  reserve  specifically  in
                  respect  thereof has been made in the Accounts or specifically
                  referred to in the notes to the Accounts;

             (b)  to the extent  that that  Liability  to  Taxation  was paid or
                  discharged on or before the Balance Sheet Date;

             (c)  to the  extent  that the Tax  Claim  arises as a result of the
                  appropriate  provision  or  reserves  in  the  Accounts  being
                  insufficient  by reason of an increase in the rate of Taxation
                  (or a variation in the method of applying or  calculating  the
                  rate of Taxation) made after the date hereof

             (d)  for which the  Company  is or may become  wholly or  primarily
                  liable as a result of  transactions  in the ordinary course of
                  business after the Balance Sheet Date;

             (e)  to the extent  that no actual  loss is suffered by the Company
                  by reason that  Liability  to  Taxation  has been made good or
                  otherwise  compensated for at no expense to the Company by the
                  Sellers  or any of them  under  any  other  provision  of this
                  Agreement or by any other party;

5.7          No claim by the  Purchaser  under the  provisions  of this Clause 5
             shall be  prejudiced  nor  shall the  amount  of any such  claim be
             reduced in consequence of any  information  relating to the Company
             which may at any time have come to the  knowledge of the  Purchaser
             or any of its  advisers  (other than  information  contained in the
             Disclosure  Letter and any annexure  thereto) and it shall not be a
             defence to any claim against the Sellers that the Purchaser knew or
             ought  to  have  known  or  had   constructive   knowledge  of  any
             information  (other  than  information  contained  or  supplied  as
             aforesaid) relating to the circumstances giving rise to such claim.

5.8          The Sellers  Warranties  are separate and  independent  and save as
             expressly  provided in this Agreement or in the  Disclosure  Letter
             shall  not be  limited  by  reference  to any  other  paragraph  or
             anything in this Agreement and such Sellers Warranties shall remain
             in full force and effect notwithstanding Completion.

5.9          The  Sellers  undertake  to  indemnify  the  Purchaser  against any
             reasonable  costs and expenses  which the Purchaser may  reasonably
             incur  either  before or after the  commencement  of any  action in
             connection with:

5.9.1        the settlement of any claim brought on reasonable  grounds that any
             of the Sellers  Warranties  are untrue or  misleading  or have been
             breached;

5.9.2        any legal proceedings in which the Purchaser claims that any of the
             Sellers  Warranties  are untrue or misleading or have been breached
             and in which judgment is given for the Purchaser; or

5.9.3        the enforcement of any such settlement or judgment.

5.10         The Sellers undertake (in the event of any claim being made against
             any of them in  connection  with  the  sale  of the  Shares  to the
             Purchaser) not to make any claim against the Company, or a director
             or an employee of the Company (other than a Seller), on whom any of
             them may have relied before  agreeing to any term of this Agreement
             or authorising  any statement in the Disclosure  Letter but so that
             this shall not preclude any Seller from claiming  against any other
             Seller under any right of contribution or indemnity to which he may
             be entitled,  and each Seller hereby agrees to consent to the grant
             of  injunctive  relief  to  restrain  a breach  of the  undertaking
             contained in this sub-paragraph if requested by the Purchaser so to
             do.

5.11         The  liability of the Sellers  shall be joint and several and shall
             bind their respective successors and personal representatives.

6.           COMPLIANCE WITH US LAW

             Each Seller severally:

6.1          warrants and represents to the Purchaser that the Seller:-

6.1.1        is acquiring the  Consideration  Shares for his own account and not
             for the  account or benefit of any other  person  including  any US
             Person;

6.1.2        is not an officer or director of any  affiliate of the Purchaser or
             any of its affiliates;

6.1.3        was not organised for the specific  purpose of holding or acquiring
             the  Consideration  Shares (if the Seller is a corporation,  trust,
             partnership or other organisation).

6.1.4        is not a U.S Person..

6.2          acknowledges and agrees that the Consideration Shares have not been
             registered  under  the  Act  and may be  offered  or  sold  only in
             accordance  with the  provisions  of  Regulation  S under  the Act,
             pursuant to a registration  of the  Consideration  Shares under the
             Act or pursuant to an exemption from the registration  requirements
             of the Act  and  further  acknowledges  that  hedging  transactions
             involving the  Consideration  Shares may not be conducted unless in
             compliance with the Act.

6.3          acknowledges and agrees that the Purchaser shall refuse to register
             any  transfer of the  Consideration  Shares not made in  accordance
             with the  provisions of  Regulation S under the Act,  pursuant to a
             registration of the Consideration Shares under the Act, or pursuant
             to an exemption from the registration requirements of the Act.

6.4          acknowledges  that the  Consideration  Shares are being offered and
             sold  to  him  in  reliance  on   specific   exemptions   from  the
             registration  requirements  of the United States  Federal and State
             securities  laws and that the  Purchaser  is relying upon the truth
             and  accuracy  of  the  representations,   warranties,  agreements,
             acknowledgements  and understandings of the Seller set forth herein
             in order to determine the  applicability of such exemptions and the
             suitability of Seller to acquire the Consideration Shares;

6.5          acknowledges that it is his responsibility to satisfy himself as to
             the  full  observance  by  this  transaction  and  the  sale of the
             Consideration Shares to him of the laws of any jurisdiction outside
             the United States and that he has done so;

6.6          acknowledges  that in  view of the  United  States  Securities  and
             Exchange Commission,  the statutory basis for the exemption claimed
             for the transactions  would not be present if the offer and sale of
             the Consideration  Shares to the Seller is part of a plan or scheme
             to evade  the  registration  provisions  of the Act and the  Seller
             confirms  that  this  transaction  is not part of any such  plan or
             scheme;

6.7          has received and carefully  reviewed the Purchaser's  Annual Report
             on Form 10-K for the fiscal  year ended  June 30,  1998,  Quarterly
             Reports on Form 10-Q for the quarters ended  September 30, 1998 and
             December  31,  1998,  Current  Reports on Form 8-K dated  August 12
             1998,  October  29 1998 and  January  28 1999  and the 1998  Annual
             Report  to  Stockholders;  and the  Sellers  have had a  reasonable
             opportunity  to ask  questions  of and  receive  answers  from  the
             Purchaser  concerning the  Purchaser,  and to obtain any additional
             information  reasonably  necessary  to verify the  accuracy  of the
             information  furnished to the Seller  concerning  the Purchaser and
             all  such  questions,  if  any,  have  been  answered  to the  full
             satisfaction of the Seller.

6.8          acknowledges that no  representations  or warranties have been made
             to him by the Purchaser or any agent,  employee or affiliate of the
             Purchaser and in entering into this  transaction  the Seller is not
             relying  upon any  information,  other than that  contained in this
             Agreement  or  specifically  referred  to in  Clause  6.7,  and the
             results of independent investigations by the Seller;

6.9          has  not  sold,  exchanged,   transferred,   pledged,  disposed  or
             otherwise  reduced his risk  relative to the  Consideration  Shares
             during the 30 day period  preceding the date hereof and  represents
             to  Parexel  in  the  same  terms  as  have  been   represented  to
             Pricewaterhouse Coopers in the letter to them annexed hereto.

6.10         acknowledges  and agrees  that this  transaction  is intended to be
             accounted for as a pooling of interests  for  financial  accounting
             purposes,  and in that  regard the Seller  hereby  agrees  with the
             Purchaser  that the  Seller  will  not  sell,  exchange,  transfer,
             pledge,  dispose or  otherwise  reduce his risk in  relation to the
             Consideration  Shares  during the period  which  begins on the date
             hereof and ends at such time as the  Purchaser  publicly  announces
             financial results covering at least thirty days of  post-Completion
             combined  operations of the Purchaser and the Company (the "Pooling
             Lock-up  Period") and the  Purchaser at its  discretion,  may cause
             stop  transfer  orders to be placed  with its  transfer  agent with
             respect to the  Consideration  Shares  during the  Pooling  Lock-up
             Period;

6.11         acknowledges   and  agrees   that  all  offers  and  sales  of  the
             Consideration  Shares shall only be made in compliance with (i) the
             Pooling Lock-up Period and (ii) the Purchaser's insider trading and
             black out period policies, as from time to time in effect and (iii)
             pursuant to an effective  registration  statement  under the Act or
             pursuant to an exemption from registration under the Act.

6.12         warrants  that the Company has never,  directly or  indirectly  (i)
             used  any  corporate  funds  for  unlawful  contributions,   gifts,
             entertainment  or other  unlawful  expenses  relating to  political
             activity;  (ii) made any  unlawful  payment to foreign or  domestic
             government  officials  or  employees,  or to  foreign  or  domestic
             political  parties  or  campaigns,   from  corporate  funds;  (iii)
             violated  any  provisions  of the  United  States  Foreign  Corrupt
             Practices Act of 1977; (iv)  established or maintained any unlawful
             or unrecorded fund of monies or other assets; (v) made any false or
             fictitious  entry on its books or  records;  (vi)  made any  bribe,
             rebate,  payoff,   influence  payment,   kickback,   finder's  fee,
             commission  or  other  payment  or  compensation  of a  similar  or
             comparable  nature  whether lawful or not, to any person or entity,
             private or public,  regardless of form, whether in money,  property
             or services to obtain favourable  treatment in securing business or
             to obtain special  concessions,  or to pay for favourable treatment
             for business secured or for special  concessions  already obtained;
             (viii) submitted or caused to be submitted any false claims against
             the US  Government  or (ix)  made,  or  caused to be made any false
             statements to the US  Government  subject to  prosecution  under 18
             U.S.C. Section 1001.

6.13         warrants  that the Company has  delivered to the Purchaser a letter
             identifying all persons who are  "affiliates" of it for purposes of
             Rule 145 under the Act.

7.           Restrictive Covenants

7.1          For the purpose of assuring to the  Purchaser  the full  benefit of
             the  businesses  and goodwill of the Company each of Herve  Laurent
             and  Philippe   Conquet   hereby   undertakes  by  way  of  further
             consideration  for the  obligations  of the  Purchaser  under  this
             agreement as separate and independent agreements that:-

7.1.1        he will not at any time after Completion  disclose to any person or
             himself use for any purpose and shall use his reasonable endeavours
             to prevent  the  publication  or  disclosure  of,  any  information
             concerning the confidential  business,  accounts or finances of the
             Company or the  Subsidiaries  or any of its  clients  or  customers
             transactions  or  affairs,  which  may,  or may  have,  come to his
             knowledge;

7.1.2        for a period  of 3 years  after  Completion  he will not  except as
             hereinafter  mentioned  either on his own account or in conjunction
             with or on  behalf of any  person  firm or  company  carry on or be
             engaged concerned or interested in any trade or business  conducted
             in or from the United States of America and any country  within the
             European Union and  Switzerland  which is similar to or competitive
             with any trade or  business  carried on by the  Company  and/or the
             Subsidiaries  within the  period of two years  prior to the date of
             Completion;

7.1.3        for a period of 3 years after Completion he will not (save with the
             prior written  consent of the Purchaser)  either on his own account
             or in  conjunction  with or on behalf of any other  person  firm or
             company directly or indirectly:

             (a)  solicit or entice  away from the Company or employ any officer
                  manager or servant  whether or not such person  would commit a
                  breach of his contract of  employment by reason of leaving the
                  service of the Company; nor

             (b)  solicit or accept the custom of any person firm or corporation
                  which  during  the two years  prior to the date of  Completion
                  shall have been a customer of the Company.

             Provided that nothing in this sub-clause  shall preclude or inhibit
             any person  named in Clause 7.1 above from  carrying out his duties
             pursuant to a service  agreement or contract of employment  between
             himself and the Company.

7.2          The restrictions  contained in Clause 7.1 are considered reasonable
             by the parties but in the event that any such restriction  shall be
             found to be void but  would be  valid  if some  part  thereof  were
             deleted  or  the  period  or  area  of  application   reduced  such
             restriction  shall apply with such modification as may be necessary
             to make it valid and effective.

8.           Pension Scheme

             The provisions set out in the Fifth Schedule shall apply.

9.           General Provisions

9.1          The Sellers shall (and shall procure that any other necessary party
             shall)  execute and do all such documents acts and things as may be
             reasonably  required by the Purchaser for securing to or vesting in
             the  Purchaser  the legal and  beneficial  ownership  of the Shares
             forthwith  upon   Completion  in  accordance  with  the  terms  and
             conditions of this Agreement.

9.2          This Agreement  shall not be assignable by any party hereto without
             the prior  written  consent of the others save by the  Purchaser to
             any  affiliate  of the  Purchaser  to  which  the  Shares  shall be
             transferred  but  notwithstanding  any such  transfer the Purchaser
             shall remain bound by the obligations contained in this Agreement

9.3          If the benefit of this Agreement is assigned,  the liability of the
             Sellers  shall  be no  greater  than  it  would  have  been  if the
             Purchaser  had  remained  the owners of the Shares and had retained
             the benefit of the Sellers Warranties.

9.4          The  obligations  of the  Sellers in this  Agreement  are joint and
             several and such obligations and undertakings  shall be enforceable
             accordingly.

9.5          This  Agreement  (together  with any  document  annexed  hereto and
             signed by or on behalf of the parties hereto) constitutes the whole
             Agreement between the parties hereto and no variations hereof shall
             be effective unless made in writing.

9.6          The  provisions  of this  Agreement in so far as the same shall not
             have been  performed at  Completion  shall remain in full force and
             effect.

9.7          Any right of  termination  conferred upon either party hereby shall
             be in  addition to and without  prejudice  to all other  rights and
             remedies  available  to it and no  exercise  or failure to exercise
             such a right of termination shall constitute a waiver by that party
             of any such other right or remedy.

9.8          The Purchaser may release or compromise the liability of any of the
             Sellers  hereunder or grant to any Seller time or other  indulgence
             without affecting the liability of any other Seller hereunder.



10.          Announcements

             No party to this Agreement shall make any statement or announcement
             in connection with this transaction  except with the prior approval
             of the other  party save as may be  required  by law or save to the
             extent  necessary  to comply  with the  requirements  of the SEC or
             Nasdaq.  A party  to  this  Agreement  who  makes  a  statement  or
             announcement  necessary to comply with the  requirements of the SEC
             or Nasdaq shall use its  reasonable  endeavours to consult with the
             other parties before making that statement or announcement.

11.          Costs

             The  Parties  shall each pay their own costs of and  incidental  to
             this  Agreement and the sale and purchase  hereby agreed to be made
             and the Company shall have no liability for such costs.

12.          Notices

             Any notice  required  to be given by any party  hereto to any other
             shall be in writing and may be served  personally  or by post or by
             facsimile  and if  served  by  post  shall  be  served  by  prepaid
             registered  letter sent  through the post  (airmail if overseas) to
             the address of the party to be served as shown in this Agreement or
             such other  address as may from time to time be  notified  for this
             purpose  and any  notice  so  served  shall be  deemed to have been
             served  48 hours  after  the time on which it is posted or 96 hours
             after the time on which it was posted in the case of  airmail  post
             and in proving  such service it shall be  sufficient  to prove that
             the notice was  properly  addressed  and posted and that before the
             notice  is  sent by post to the  Sellers  a copy  shall  be sent by
             facsimile  to the  Seller's  lawyers for the  attention of M. Denis
             Polack (fax number 00 33 1 45 61 58 39) and to the Purchaser a copy
             shall  be sent to the  Purchaser's  lawyers  for the  attention  of
             Richard  Elphick  (fax  number  00 44 171 379  6854).  If served by
             facsimile,  notice  shall  be  deemed  to  have  been  served  upon
             transmission of the communication to the relevant  facsimile number
             and production by the sending  facsimile  machine of a transmission
             report  showing  that  the  facsimile  message  has  been  properly
             received by the facsimile number to which it was transmitted.

13.          Governing Law and Jurisdiction

             13.1 This Agreement shall be governed by either: (i) the law of the
             Republic of France in which case the parties  hereby  submit to the
             non-exclusive jurisdiction of the Courts in Paris; or (ii) the laws
             of England and Wales in which case the parties hereby submit to the
             non-exclusive jurisdiction of the High Court in London.

13.2         In the event that any party  initiates any proceedings it may elect
             which of the laws  referred  to above  shall  apply  and the  other
             parties shall be bound by such election and the  appropriate  Court
             shall have jurisdiction.

AS WITNESS  whereof this  Agreement has been entered into the day and year first
above written.


TABLE>
                                                THE FIRST SCHEDULE

                             PARTICULARS OF THE SELLERS, THEIR SHAREHOLDINGS (actions)

                                       IN THE COMPANY AND THE CONSIDERATION

(1)                                                       (2)                          (3)                  (4)
Names and Addresses                   No. of Ordinary  Shares                  Capital FFr        Consideration
                                                    (actions)                                            Shares
<CAPTION>
- ----------------------------------- -------------------------- ---------------------------- --------------------
<S>                                                   <C>                    <C>                        <C>
M. Laurent                                             45,239                 4,523,900,00               75,302
Herve

Comir                                                  26,680                 2,668,000,00               44,410

M. Conquet                                             43,967                 4,396,700,00               73,185
Philippe

Melle Laurent                                              16                     1,600,00                   27
Valerie

M. Baur                                                    16                     1,600,00                   27
Charles

Succession de M. Baur                                      16                     1,600,00                   27
Francois

Melle Laurent                                              16                     1,600,00                   27
Caroline

Mme Laurent                                                16                     1,600,00                   27
Karine

Finanval                                                4,008                   400,800,00                6,671

M. Chahid-Nourai                                           15                     1,500,00                   25
Behrouz

M. Leroux                                                   5                       500,00                    8
Yvon

Mme Conquet                                                 5                       500,00                    8
Caroline

La Senlisienne                                              1                       100,00                    2
de Portefeuille
(action pretee par Comir)
</TABLE>
                               THE SECOND SCHEDULE

                    BASIC INFORMATION CONCERNING THE COMPANY

                               THE SECOND SCHEDULE


1.            Registered number               :   B 411 470 487

2.            Date of Registration            :   25 March 1997

3.            Address of registered office    :   12 rue de Lorraine
                                                   92300 Levallois Perret

4.            Registered capital              :   12,000,000 FF (120,000 shares
                                                  of 100 FF each)

5.            Directors Full Names                CONQUET Philippe
                                                  LAURENT Herve
                                                  CHAID-NOURAI Behrouz
                                                  AOUSTIN- LAURENT Karine
                                                  CONQUET Caroline
                                                  LA SENLISIENNE DE PORTEFEUILLE

6.            Auditors:                           Polack, Thierry




<TABLE>
                                                THE THIRD SCHEDULE

                                            PARTICULARS OF SUBSIDIARIES



Name                         Date   and   Place   of               Share     Held by                   Beneficially
                             Incorporation   and                 Capital                               owned by
                             Registered Number
<CAPTION>
- -------------------------------------------------------------------------------------------------------------------------
<S>                         <C>                                   <C>       <C>                                <C>
Biostat                       9 December 1985,                     5,123     PharMedicom               PharMedicom
                             B334 323 979 (81B 02180)                  1     H. Laurent                          "
                                                                       1     V. Laurent                          "
                                                                       1     C. Baur                             "
                                                                       1     C. Laurent                          "
                                                                       1     K. Laurent                          "
                                                                       1     P. Conquet                          "
                                                                       1     Comir                               "


Droit & Pharmacie            1 October 1956                        7,812     PharMedicom               PharMedicom
                             B562 108 084 (97B04948)                   1     P. Conquet                          "
                                                                       1     C. Conquet                          "
                                                                       1     B.C Nourai                          "

Cercles                      22 May 1993                                 499 Pharmedicom               Pharmedicom
                             391 324 373                                   1                                     "
                             RCS Nanterre (95B3191)
                             Paris

</TABLE>


<TABLE> 
                                               THE FOURTH SCHEDULE

                                                     PROPERTY



Short Description of Property                               Expiry of Lease                  Owner if Leasehold
<CAPTION>
- ------------------------------------------- --------------- -------------------------------- ----------------------
<S>                                                        <C>                              <C>
Offices at 12 rue de Lorraine, 92300                        30 June 2006                     Comir
Levallois Perret, Paris
15 Avenue  des  Droits de  l'Homme,  45000                  3 July 2004                      SCI Oxford
Orleans

</TABLE>















                              THE FIFTH SCHEDULE

                     PROVISIONS AFFECTING THE PENSION SCHEME



1.           The Group  contributes  to those  pension  schemes on behalf of its
             employees more particularly  described in the documents at Annex 15
             of the Disclosure Letter provided to the Purchaser.

2.           There are no schemes other than those  referred to in the paragraph
             above to which any members of the Group are  obliged to  contribute
             funds.






                                                THE SIXTH SCHEDULE

                                                SELLER'S WARRANTIES



In this Schedule (save where the context otherwise requires) the expression "the
Company" shall mean each of the Company and each of its Subsidiaries.

The Sellers  jointly and  severally  provide the following  Representations  and
Warranties.  Each  Representation  and Warranty shall be construed as a separate
representation and warranty and shall be deemed to survive Completion.

The  warranties  and  representations  referred to in Clause 5 of the  foregoing
Agreement are that:-

1.           CONSTITUTION OF THE COMPANY

1.1          Ownership of Shares; Authorisation

             (a)  Each  Seller has full and valid  title to the Shares  owned by
                  him as specified in the First Schedule  hereto and such Shares
                  are free of all Encumbrances.  The Sellers hereby deliver good
                  and  marketable  title to all of the  Shares to the  Purchaser
                  free of all Encumbrances.

             (b)  Each Seller has the power and capacity to execute, deliver and
                  carry out the terms and  provisions of this  Agreement and has
                  taken all  necessary  action to authorise  the  execution  and
                  performance of this  Agreement.  This Agreement  constitutes a
                  valid and binding  obligation  on each Seller  enforceable  in
                  accordance with its terms.

             (c)  Each  Seller  has  obtained  all the  consents,  approvals  or
                  authorisations  required in connection  with the execution and
                  performance of this Agreement by it.

             (d)  The  execution  and  performance  of  this  Agreement  and the
                  transactions  stipulated  herein  will  not,  with or  without
                  notice and/or lapse of time, result in a breach of or conflict
                  with  any  provision,  covenant  or  obligation  of any of the
                  Sellers  or in the  modification  or  termination  of any such
                  covenant or obligation.



1.2          Corporate Organisation of the Company

             (a)  The Company is a corporation  (societe anonyme) duly organised
                  and validly  existing under the laws of the Republic of France
                  with all requisite  corporate  power and authority to carry on
                  its business as it is now being conducted.

             (b)  The  articles  of  association  and by-laws  (statuts)  of the
                  Company and the Extrait  k-bis,  a copy of which is annexed to
                  the  Disclosure  Letter,  are  complete  and  up-to-date.  The
                  Company  has  been  in   compliance   with  its   articles  of
                  association and by-laws since its formation.

             (c)  The  Company  has a share  capital  of twelve  million  French
                  francs  (FRF 12,000,000)  divided  into (i)  120,000  ordinary
                  shares with a par value of 100FRF per share,  all of which are
                  validly  issued and fully paid.  The aforesaid  securities are
                  the only  outstanding  interests in the capital of the Company
                  and  there  is  no  outstanding  subscription  right,  option,
                  conversion   right,   warrant,   pre-emptive  right  or  other
                  agreement providing for the purchase,  issuance or sale of any
                  securities  representative of the capital or any voting rights
                  of the Company whatsoever.

             (d)  The Company is not the subject of any judicial, administrative
                  or   amicable   procedure   of  judicial   reorganisation   or
                  liquidation, reorganisation, winding-up or liquidation, nor is
                  it  in  a  state  of   insolvency   (cessation  de  paiements)
                  (inability  to  satisfy  its  debts  as  they  fall  due).  No
                  administrator  (mandataire ad hoc) has been  designated by any
                  court  or  been  requested  to be  designated  to  assist  the
                  Company. The Company does not fall within the scope of Article
                  241 of the Act of July 1966 with  respect to  insufficient  or
                  impaired capital.

1.3          Subsidiaries; Secondary Establishments

             The  Company has the  subsidiaries  details of which are set out in
             the Second  Schedule.  It has no investments of any kind whatsoever
             in any other  entity,  nor has it entered  into any  agreements  or
             commitments  relating to the  acquisition  of any investment in any
             other   entity.   The   Company   does  not   have  any   secondary
             establishments.

1.4          The Shares

             (a)  No one is  entitled  to receive  from the  Company any finders
                  fee,  brokerage,  or other  commission in connection  with the
                  purchase of shares in the Company or any Associate  company of
                  the Company.

             (b)  Save as provided in this  Agreement  no share or loan  capital
                  has been  issued or agreed to be issued by the  Company  since
                  the Balance Sheet Date.
1.5          Title to Assets

             The Company has good and valid  title free of any  Encumbrances  to
             all assets necessary for the operation of the Business. Such assets
             are in good  condition  and are  adequate  and  sufficient  for the
             Business  of the  Company.  No  Person  has any  right or option to
             purchase, lease or use any such assets.

             The Fourth  Schedule  contains  details of all of the various  real
             property in and on the premises of which the Company carries on the
             Business  and such real  property  in  respect  of which it holds a
             right of  occupancy  and/or  purchase  under  lease  agreements  or
             capital lease agreements.

1.6          Litigation 

             (a)  There is no Proceeding pending against the Company and, to the
                  best  knowledge of the  Sellers,  there are no facts likely to
                  result in any Proceeding.

             (b)  There are not now,  nor have there been during the twenty four
                  months   prior   to  the   date   hereof,   any   governmental
                  investigations  or  disciplinary  proceedings  concerning  the
                  Company or the Business.  The last audit of the Company by the
                  tax  authorities  took place on January  1995 for  Biostat and
                  covered  the  period  up to  December  1994  and for  Droit et
                  Pharmacie  it took place in October  1994 for the period up to
                  31  December  1993.  The  Company   provided  all  information
                  requested   by  the   authorities   and  all  other   relevant
                  information  necessary in connection with such audit, and such
                  information was true and accurate.

             (c)  There has never been any issue  which could have given rise to
                  a product/service  liability claim against the Company and the
                  Sellers are not aware of any facts or matters which could give
                  rise to such claim in the future.


 .7          Compliance with Laws

             (a)  The Company has not violated any law, order,  rule,  ordinance
                  or, more generally,  any regulation relating to the use of its
                  assets or the operation of the  Business,  and the Business is
                  currently  operated in compliance  with all  applicable  laws,
                  statutes,  regulations,  orders and  decrees in force,  and in
                  particular,   statutory   provisions   relating   to  pricing,
                  competition and the obtaining of grants and subsidies.

             (b)  The Company has all permits, licences and other authorisations
                  (and is in compliance  with the terms and conditions  thereof)
                  required by the statutory and regulatory  provisions in force.
                  In particular, the Company has all permits, licences and other
                  authorisations  (and  is in  compliance  with  the  terms  and
                  conditions  thereof) required under  Environmental Law or laws
                  and regulations governing public health and safety.

             (c)  The  Company  has  not  received   written   notice  from  any
                  Governmental  Authority or other regulatory body of any matter
                  (i) relating to any breach or  non-compliance  with any law or
                  regulation,  or (ii)  which is likely to form the basis of any
                  Proceeding.

             (d)  The assets (including plant and machinery) used by the Company
                  are in compliance  with the provisions of applicable  laws and
                  regulation  governing  environmental  health and public health
                  and safety;

             (e)  All   permits,   licences  and   authorisations   required  in
                  connection  with the use and/or  occupancy  by the  Company of
                  real  property  or the  construction  of any  building  or the
                  carrying  out of any works by the  Company on such  properties
                  have been obtained and remain valid.

1.8          Effect of Agreement 

             Neither the  execution or  performance  of this  Agreement  nor the
             consummation  of the  transactions  contemplated  herein  will  (a)
             violate any law  applicable to the Company (b) result in the breach
             or termination of any  agreement,  permit or licence  applicable to
             the Company or entitle any third party to renegotiate or modify the
             terms thereof or (c) result in the creation of or imposition of any
             Encumbrance  upon the Business or any of the assets of the Company.
             Neither the  acquisition  of the Shares,  nor  compliance  with the
             terms of this Agreement will (x) result in any present indebtedness
             of the Company  becoming  due or capable of being  declared due and
             payable  prior to its stated  maturity or (y) give rise to or cause
             to become exercisable any material right in respect of the Company.
             The  Company  has not  received  any  grant or  benefited  from any
             concession made by any governmental agency or authority in relation
             to the Business which,  in the case of a grant,  will become liable
             to be repaid  in whole or in part or, in the case of a  concession,
             will be lost or  forfeited  in whole or in part as a result  of the
             transactions contemplated in this Agreement.

1.9          Sellers' other interests

             No Seller nor any Associate of any Seller has any estate,  right or
             interest,  directly or indirectly,  in any business other than that
             now carried on by the Company which is or is likely to be or become
             competitive  with the business or the proposed  business (as at the
             date  hereof)  of the  Company  save as the  registered  holder  or
             beneficial  owner of any class of securities of any company if such
             class of securities is listed on any recognised investment exchange
             and in respect  of which  such  person  holds,  or is  beneficially
             interested in,  (together with his  Associates)  less than five per
             cent. of any single class of the securities in that company.

2.           ACCOUNTS

2.1          Financial Statements

             (a)  The  Accounts,  have  been  prepared  in  accordance  with all
                  applicable laws and generally accepted accounting principles.

             (b)  As of the Balance Sheet Date,  the Company had no  liabilities
                  (including  off-balance sheet liabilities) which were required
                  to  be  reflected  in  financial   statements  that  were  not
                  reflected or  adequately  reserved  against  according to such
                  principles  in a manner  consistent  with the  Company's  past
                  practices  and  procedures.  Since the Balance  Sheet Date the
                  Company has not incurred any liability except liabilities that
                  were  incurred  in the usual  and  normal  course of  business
                  consistent with the Company's past practices.

             (c)  The Company has not  declared or paid any  dividends  or other
                  distributions  or paid any special  drawings since the Balance
                  Sheet Date.



             (d)  The  Accounts  give a true and  fair  view of the  assets  and
                  liabilities  of the Company at the Balance  Sheet Date and the
                  profits of the Company for the financial  period ended on that
                  date;

             (e)  The  Accounts  apply  accounting   policies  which  have  been
                  consistently  applied in the audited  balance sheet and profit
                  and loss  accounts  for the  three  financial  years  prior to
                  theBalance Sheet Date;

             (f)  The Accounts  properly  reflect the financial  position of the
                  Company as at the Balance Sheet Date.

2.2          US GAAP Accounts

             The balance sheets of the Company as of the Balance Sheet Date, and
             the   statements   of   operations,   cash  flows  and  changes  in
             stockholders'  equity  of the  Company  for that  fiscal  year then
             ended,  as  prepared  by  Pricewaterhouse  Coopers,  shall be known
             collectively  as the  Financial  Statements.  Each  of the  balance
             sheets included in the Financial  Statements fairly presents in all
             material  respects the financial  position of the Company as of its
             date, and the other statements included in the Financial Statements
             fairly present in all material  respects the results of operations,
             cash  flows  and  stockholders  equity,  as the case may be, of the
             Company  for  the  periods  therein  set  forth,  in  each  case in
             accordance  with generally  accepted  accounting  principles in the
             United  States  consistently  applied  during the periods  involved
             except as otherwise stated therein.

2.3          March Accounts

             The  March  Accounts  give a true and fair view of the  assets  and
             liabilities  of the  Company as at 31 March 1999 and the  projected
             profits of the Company as at that date.

2.4          Tax Provisions

             To the extent  required by the  Statements  of Standard  Accounting
             Practice and the  Financial  Reporting  Standards  applicable  to a
             French  company  provision or reserve has been made in the Accounts
             and  March  Accounts  for all  Taxation  assessed  or  liable to be
             assessed on the Company or for which it is  accountable  in respect
             of income  profits or gains earned accrued or received on or before
             the 31 March  1999 or any  event  on or  before  the 31 March  1999
             including  distributions  made down to such date or provided for in
             the Accounts and proper provision has been made in the Accounts for
             deferred taxation.

2.5          Work in progress

             In the Accounts:-

             (a)  the Company's work in progress/inventory  has been valued on a
                  basis  consistent  with that  adopted  for the  purpose of the
                  Company's audited accounts in respect of the beginning and end
                  of each of the three last preceding accounting periods;

             (b)  redundant  or obsolete  work in  progress/inventory  as at the
                  Balance Sheet Date has been wholly written off;

             (c)  the   value   attributed   to  each   item  of  the   work  in
                  progress/inventory  included in the  Accounts  does not exceed
                  the lower of cost and realisable value as at the Balance Sheet
                  Date;

2.6          Books and Records

             All  accounts,  books,  ledgers,  financial  and other  records  of
             whatsoever kind of the Company:-

             (a)  have been fully properly and accurately  maintained are in the
                  possession of the Company and contain due and accurate records
                  of all matters required to be entered into therein;

             (b)  do  not  contain  or  reflect  any  material  inaccuracies  or
                  discrepancies;

             (c)  give and  reflect  a true and fair view of the  matters  which
                  ought to appear therein.

             Debts

2.7          No amount  included  in the  Accounts as owing to the Company as at
             the Balance  Sheet Date was more than three months  overdue nor has
             any such amount been  released for an amount less than the value at
             which it was  included  in the  Accounts  nor is any such  debt now
             regarded by the Sellers as irrecoverable in whole or in part.

2.8          The Company has not factored or  discounted  its debts or agreed to
             do so.

 




3.1          Financial Position and Prospects

             There has been no material  deterioration in the financial position
             or  prospects  or turnover of the Company  since the Balance  Sheet
             Date.

3.2          Capital Commitments

             There were no  commitments  on capital  account  outstanding at the
             Balance  Sheet Date (save as disclosed in the  Accounts)  and since
             the said date the Company has not entered  into, or agreed to enter
             into, any material capital commitments.

3.3          Borrowings

             The total amount borrowed by the Company and its Subsidiaries  from
             its bankers does not exceed its overdraft  facilities and the total
             amount borrowed by the Company and its Subsidiaries from whatsoever
             source does not exceed any limitation on its borrowing contained in
             the articles of  association  and by-laws  (statuts)  of, or in any
             other instrument executed by, the Company or any Subsidiary.

3.4          Bank accounts

             A statement  of the bank  accounts of the Company and of the credit
             or debit balances on such accounts as at a date not more than seven
             days before the date hereof has been supplied to the Purchaser. The
             Company  has not any other bank or  deposit  accounts  (whether  in
             credit or  overdrawn)  not included in such  statement.  Since such
             statement  there  have been no  payments  out of any such  accounts
             except for routine payments and the balances on current account are
             not now  substantially  different  from the balances  shown on such
             statements.

3.5          Distributions and Loan Repayments

             All dividends or distributions of profits  declared,  made, or paid
             by the Company since the date of  incorporation of the Company have
             been  declared,  made, or paid in  accordance  with its articles of
             association and by-laws (statuts) or other relevant legislation.


3.6          Continuance of facilities

             In  relation to all  debentures,  acceptance  credits,  overdrafts,
             loans or other financial facilities outstanding or available to the
             Company ("facilities"):-

             (a)  the Sellers  have  supplied to the  Purchaser  in writing full
                  details  thereof and true and correct  copies of all documents
                  relating thereto;

             (b)  neither the Sellers,  nor the Company,  has done  anything nor
                  are  the  Sellers  aware  of  any  circumstances  whereby  the
                  continuance  of any facility in full force and effect might be
                  affected  or  prejudiced  or  which  might  give  rise  to any
                  detrimental  alteration  in the terms or  conditions of any of
                  the facilities;

             (c)  none of the  facilities  is  dependent  upon the  guarantee or
                  indemnity of or any  security  provided by a third party other
                  than the Company or a Subsidiary;

             (d)  no Seller has any  knowledge,  information or belief that as a
                  result of the  acquisition  of the Shares by the  Purchaser or
                  Completion any of the facilities might be terminated or mature
                  prior to its stated maturity.

3.7          Real Property Leases and Capital Leases (Credit-baux)

             Set out in the Fourth Schedule is a detailed list of all leases and
             capital  leases of real  property used in the Business (the "Leases
             and Capital  Leases").  All of the Leases and Capital Leases are in
             full force and effect.

4.           COMMERCIAL

4.1          Contracts 

             Save for those contracts  (including the Leases and Capital Leases)
             and other documents listed in the Disclosure Letter complete copies
             of which have been made  available for  inspection by the Buyer and
             its agents prior to the date hereof (the "Contracts"), there are no
             other material  contracts  relating to the Company or the Business.
             For these purposes,  "material  contracts"  shall mean contracts in
             respect  of which  (i) the  obligations  of  either  party  thereto
             involve expenditure in excess of one hundred thousand French francs
             (FRF 100,000) per annum, or (ii) more than three (3) months' notice
             of termination is required.


4.2          Breach of Contracts

             The  Company is not,  nor has it been in a  situation  of breach or
             default of any of the Contracts.

4.3          Insider Contracts

             (a)  There is not outstanding, and there has not at any time during
                  the last three years been  outstanding,  any  contract  (other
                  than a contract of  employment)  or  arrangement  to which the
                  Company is a party and in which any Seller or any Associate of
                  any Seller or any director of the Company or any  Associate of
                  any such director is or has been interested,  whether directly
                  or indirectly.

             (b)  The Company is not a party to, nor have its profits during the
                  last three years been affected by, any contract or arrangement
                  which is not of an entirely arms' length nature.

4.4          Other Party's Defaults

             So far as the Sellers are aware,  no party to any agreement with or
             obligation to the Company is in default  thereunder being a default
             which would be material in the context of the  financial or trading
             position  of the  Company nor (so far as the Sellers are aware) are
             there any circumstances likely to give rise to such a default.

4.5          Other Material contracts

             The  Company  is not a  party  to  nor  subject  to any  agreement,
             transaction, obligation, commitment, understanding,  arrangement or
             liability which:-

             (a)  is incapable of complete  performance  in accordance  with its
                  terms within six months after the date on which it was entered
                  into or undertaken; or

             (b)  is known by any Seller to be likely to result in a loss to the
                  Company on completion of performance; or

             (c)  cannot  readily be  fulfilled  or  performed by the Company on
                  time and without undue or unusual expenditure of money, effort
                  or personnel; or

             (d)  involves  or is likely to involve  obligations,  restrictions,
                  expenditure or receipts of an unusual,  onerous or exceptional
                  nature  and  not  in the  ordinary  course  of  the  Company's
                  business; or

             (e)  is a contract  for hire or rent hire  purchase  or purchase by
                  way of credit sale or periodical payment; or

             (f)  is a  contract  with any trade  union or body or  organisation
                  representing its employees; or

             (g)  requires an aggregate  consideration payable by the Company in
                  excess of FFr100,000; or

             (h)  involves  or is likely to involve the supply of services by or
                  to the  Company  the  aggregate  sales  value  of  which  will
                  represent  in excess of ten per cent.  of the  turnover of the
                  Company for the last financial year; or

             (i)  requires  the  Company  to pay any  commission,  finders  fee,
                  royalty or the like; or

             (j)  is in any way otherwise than in the ordinary and proper course
                  of the Company's business; or

             (k)  would have been such an agreement or  arrangement  but for its
                  cancellation  or  termination by any  counter-party  since the
                  Balance Sheet Date.

4.6          Employment Matters

             (a)  The Disclosure  Letter contains a true and complete list as of
                  the date hereof of the names, of job titles, salaries, working
                  hours per week,  date of hire and date of birth of all persons
                  who are currently  full or part-time  employees of the Company
                  and no other persons are so employed.

             (b)  The   only   collective   bargaining   agreement   (convention
                  collective)   applicable   to  the  Company  is  the  National
                  Collective Bargaining Agreement for consulting and engineering
                  activities (No. 3018).

             (c)  Since the Balance Sheet Date no change has been made or agreed
                  in the rate of remuneration,  the emoluments or the pension or
                  other  benefits of any executive or employee and no employees,
                  agents or consultants have been hired by the Company.

             (d)  No collective  lay-offs  involving more than ten employees are
                  currently in progress within the Company.

             (e)  The Company has not experienced  any strike,  labour unrest or
                  collective labour  controversies during the past two (2) years
                  and no such disturbances are currently threatened.

             (f)  The  Company has duly held all  elections  required to be held
                  for the purposes of appointing workers' representatives within
                  the Company.

             (g)  The Company does not breach, and has not breached, any laws or
                  regulations  relating to the  recruitment  of  personnel  on a
                  temporary or fixed-term basis.

4.7          Special Employee Benefits

             Except  for  the  plans,  benefits,   bonuses,   welfare,  pension,
             retirement, profit sharing and other compensation plans required to
             be  maintained by law and  described in the Fifth  Schedule  hereto
             (collectively, the "Plans"), the Company is not a party to any plan
             or  agreement  having as its  purpose or effect the payment of such
             sums or the provision of such benefits.  Each of the Plans has been
             administered in accordance with all applicable laws and regulations
             and all  payments  required  to be made  under such Plans have been
             made. The Company is not under any obligation to pay any person any
             additional  amount  over  and  above  that  provided  for by law in
             respect of any pension or early retirement benefit, gratuity, death
             benefit,  disability  benefit or similar  benefit on an  individual
             basis.

4.8          Intellectual Property

             (a)  Set forth in the  Disclosure  Letter is a list of the patents,
                  trademarks,   trade  names,  copyrights,   logos  and  designs
                  currently used by the Company in connection  with the Business
                  (together   the   "Intellectual   Property").   None   of  the
                  Intellectual Property is licensed to or from a third party. No
                  third  party  is  breaching  the   Company's   rights  to  its
                  Intellectual Property.

             (b)  The Company has good and marketable title,  (fully enforceable
                  against third parties),  free of Encumbrances  to, or the free
                  right to use,  all  intellectual  property  necessary  for the
                  conduct of its business as presently conducted. The Company is
                  not infringing any patent,  trade name, copyright or trademark
                  of  any  third  party,   nor  will  the   conclusion   of  the
                  transactions   envisaged  by  this  Agreement  result  in  the
                  infringement of any third party's rights.

             (c)  All necessary  steps have been taken by the Company to protect
                  its rights to the Intellectual Property and in particular, the
                  Intellectual  Property has been duly  registered or filed with
                  the  appropriate  authority and there are no adverse claims of
                  any  third  party   pertaining  to  any  of  the  Intellectual
                  Property.

4.9          Taxes

             (a)  All returns, declarations and reports (the "Returns") required
                  to be delivered by the Company to any taxation  authority have
                  been properly prepared and delivered and no Return is disputed
                  by the relevant Taxation Authority.  All Taxation that was due
                  and payable by the  Company  prior to the date hereof has been
                  paid.

             (b)  There  are  no  pending  audits,  investigations  or  disputes
                  involving the Company relating to Taxation.

             (c)  None of the current  activities  of the  Company  causes it to
                  have a taxable  presence  or  permanent  establishment  in any
                  country other than France.

             (d)  All social  security  charges (both  employer's and employee's
                  parts) required to be withheld in respect of compensation paid
                  to employees of the Company have been withheld and paid to the
                  relevant authority or social security institution,  and income
                  withholding  taxes, if any, payable by the Company as employer
                  have been duly paid and the relevant  tax and social  security
                  returns and records are in good order.

4.10         Debts; Loans

             (a)  Except  as  set  forth  in the  Disclosure  Letter  (which  in
                  particular sets out complete and accurate details of all loans
                  extended  to the  Company),  there  are no  sums  owed  by the
                  Company to any third party (including shareholders) other than
                  debts which have arisen in the ordinary course of business and
                  for  the  purpose  only  of  carrying  on its  normal  trading
                  activities,  nor has the  Company  lent any money to any third
                  party other than in the ordinary course of business.

             (b)  All  trade  debts  owed  by   customers  to  the  Company  are
                  collectible  within a maximum  period of ninety  days from the
                  relevant invoice date.

4.11         Insurance

             The Company has effected adequate  insurance  relating to all risks
             that companies having similar business  activities  normally cover.
             All of the  policies  of  insurance  maintained  by the  Company in
             relation  to the  Business  and  its  assets  (the  "Policies")  (a
             complete list of which is set forth in the  Disclosure  Letter) are
             in full force and effect.  All premiums  payable under the Policies
             have been paid and no  notices  of  termination,  or  intention  to
             terminate  such policies,  have been  received.  No claim under any
             insurance  policy taken out in respect of the assets of the Company
             or the Business is currently outstanding.

4.12         Conduct of Business since the Balance Sheet Date

             Since the Balance  Sheet Date,  the Business has been carried on by
             the Company in the ordinary and usual course and  substantially  in
             the  same  manner  as  conducted  during  the  twelve  (12)  months
             preceding the Balance Sheet Date.

4.13         Sureties and Guarantees 

             The Company has not been  granted any  guarantee of or security for
             any overdraft,  loan or loan facility extended to it in relation to
             the Business.  The Company has not provided any guarantee or surety
             for the performance of  undertakings  entered into by third parties
             or its shareholders, corporate officers or members of staff, nor is
             it liable to any third  party for the  performance  or  failure  to
             perform  of any  Person,  nor has it issued any  comfort  letter in
             their favour.

4.14         Inventory/Backlog

             The current  backlog of the  Company as  provided to the  Purchaser
             consists of items of a quality and quantity  usable and billable in
             the normal course of business.

4.15         Subsidies

             (a)  Set  forth in the  Disclosure  Letter is a  complete  list and
                  summary  of the  terms of  those  governmental,  regional  and
                  departmental grants,  advances,  subsidies and aids from which
                  the Company benefits as of the date hereof.

             (b)  The  Company  has not  carried  out any act that may cause the
                  refund  in  full  or in  part  of any  grant,  subsidy  or aid
                  received by the  Company in relation to the  Business or cause
                  any  application  made  by  the  Company  in  relation  to the
                  Business for such a grant, subsidy or aid to be refused wholly
                  or partly,  and the signature of this Agreement shall not have
                  such result.

4.16         Products/Services

             Except for any condition,  warranty,  representation  or obligation
             implied by law or contained  in its  standard  terms of business or
             otherwise given, made or accepted in the normal course of business,
             the  Company  has not  provided  any  other  warranty  or made  any
             representation,  or assumed any material  obligation  in respect of
             the quality of services supplied or agreed to be supplied by it.

4.17         Brokers' Fees

             All  negotiations  relating to this Agreement and the  transactions
             provided for herein have been  carried on without the  intervention
             of third  parties  acting on behalf  of any of the  Sellers  or the
             Company  who could on that basis  make a valid  claim  against  the
             Company or the  Purchaser  for any  finders' fee or  commission  or
             similar  compensation  in connection with the  transactions  hereby
             contemplated.

4.18         Year 2000;

             The Company is Year 2000 compliant in all respects.

4.19         Suppliers and Customers

             There is no supplier from whom the Company makes purchases, nor any
             customer  to whom the  Company  makes  sales,  which in either case
             represents  more than five per cent  (5%) of the  Company's  annual
             turnover.

4.20         Information

             All information in this Agreement, including the Schedules, and the
             information   provided  by  the  Company  or  the  Sellers  to  the
             Purchaser,  is true,  complete  and  correct.  The Sellers have not
             failed to disclose to the Purchaser any  determinative  information
             or item concerning the Company.

5.           BUSINESS OF THE COMPANY

5.1          Changes since the Balance Sheet Date

             Since the Balance Sheet Date the Company:-

             (a)  has carried on its business in the ordinary and usual course;

             (b)  has not entered into any transaction nor assumed any liability
                  nor made any payment not provided for in the Accounts which is
                  material and is not in the ordinary course of its business;

             (c)  has  carried  on the  business  without  any  interruption  or
                  alteration in the nature scope or manner of its business;

             (d)  has not  borrowed  or raised any money or taken any  financial
                  facility  (except such short term  borrowings from its bankers
                  as are disclosed in the Disclosure Letter);

             (e)  has paid its  creditors  within  the  times  agreed  with such
                  creditors and there are not debts  outstanding  by the Company
                  which have been due for more than four weeks;

5.2          Fair Trading etc.

             No agreement  practice or arrangement  carried on by the Company or
             to which the Company is a party infringes  Article 85 of the Treaty
             establishing  the European  Economic  Community or  constitutes  an
             abuse of  dominant  position  contrary  to  Article  86 of the said
             Treaty or infringes or contravenes  any provisions of the Treaty of
             Rome;

5.3          Guarantees, Options, etc.

             Company is not a party to any  option or  pre-emption  right,  or a
             party  to any  guarantee  or  suretyship  or any  other  obligation
             (howsoever  called) to pay,  purchase or provide funds  (whether by
             the advance of money, the purchase of or subscription for shares or
             other securities, the purchase of assets or services, or otherwise)
             for the payment of, indemnity against the consequence of default in
             the  payment  of,  or   otherwise  to  be   responsible   for,  any
             indebtedness of any other person.

5.4          Tenders, etc.

             No  offer,  tender,  or the  like  not in the  ordinary  course  of
             business is outstanding which is capable of being converted into an
             obligation  of the  Company by an  acceptance  or other act of some
             other person.

5.5          Powers of Attorney, etc.

             There are no  powers  of  attorney  given by the  Company  in force
             (other than to the holder of an  Encumbrance  solely to  facilitate
             its  enforcement)  and no  person,  as  agent or  otherwise  of the
             Company, is entitled or authorised to bind or commit the Company to
             any  obligations  not  in the  ordinary  course  of  the  Company's
             business.

5.6          Grants

             No grant made to the  Company is liable to be  refunded in whole or
             in part in consequence of any action or omission of the Company.

6.           GENERAL

6.1          Material Disclosure

             The  contents  of the  Disclosure  Letter  and of all  accompanying
             documents  are true  and  accurate  in all  material  respects  and
             clearly and  accurately  disclose in all  material  respects  every
             matter to which they relate.

6.2          Loans to Sellers

             Save  as  set  out  in  the   Disclosure   Letter   there  are  not
             outstanding:-

             (a)  any  loans  made by the  Company  to the  Sellers  and/or  any
                  director of the Company and/or any Associate of the Sellers or
                  of any such director;

             (b)  any debts  owing to the  Company  by the  Sellers  and/or  any
                  director of the Company and/or  Associate of the Sellers or of
                  any such director;

             (c)  any securities for any such loans or debts as aforesaid.

6.3          Net Assets

             The  value  of  current  assets  less  current  liabilities  as  at
             Completion  is not less than their  value as at the  Balance  Sheet
             Date.

6.4          Investment, associations

             The Company:-

             (a)  is not the holder or beneficial owner of and has not agreed to
                  acquire  any class of the share or other  capital of any other
                  company or corporation  (whether  incorporated in the Republic
                  of France or elsewhere) other than the Subsidiaries;

             (b)  is  not  and  has  not  agreed  to  become  a  member  of  any
                  partnership, joint venture, consortium or other unincorporated
                  association;

6.5          Forecast

             The 12 month  forecast/budget as at 31 March 1999 was carefully and
             consistently  prepared  and does not  include any items that cannot
             reasonably be justified.  There is in existence valid documentation
             supporting  the  valuation  of   FFr28.913million  of  current  new
             business  (contracts  signed and/or  regular repeat  business);  of
             FFr16.625million  of proposed new business  (contracts not signed);
             and     FFr16.628million     of    new     business     opportunity
             (IBM/IPN/Convergence projects).


                             THE SEVENTH SCHEDULE

                    LIMITS ON CLAIMS UNDER SELLERS WARRANTIES

1.           The Sellers  shall not have any  liability  under or in relation to
             the Sellers Warranties:-

             1.1         as regards any single  claim,  unless the amount of the
                         liability thereunder exceeds FFr20,000;

             1.2         except to the extent that the  aggregate  amount of the
                         Sellers'  liability in respect of all claims  hereunder
                         exceeds  FFr100,000  and for this purpose single claims
                         excluded  by Clause 1.1 above will not to be taken into
                         account;

             1.3         as  regards   any  claim   unless   notice  in  writing
                         specifying   particulars  and  the  amount  thereof  is
                         received by the  Sellers by 2 Business  Days before the
                         earlier of (i) the delivery by Pricewaterhouse  Coopers
                         LLP  of  its  report  on  the   Purchaser's   financial
                         statements  for the  fiscal  year ended 30 June 1999 or
                         (ii) 31 March 2000;

             1.4         as regards  any claim to the extent  that such claim or
                         liability   arises  or  that  the  amount   thereof  is
                         increased  as a result of any  change in the basis rate
                         or method of calculation of any Taxation or as a result
                         of  any  other   legislation   decision  or  regulation
                         (whether or not in relation to  Taxation) or any change
                         in or in the  interpretation  of any  such  legislation
                         decision or  regulation  occurring or coming into force
                         after the date hereof.

2.           The liability of the Sellers under the Sellers  Warranties shall be
             reduced to the extent that  provision  or allowance  therefore  has
             been made in the Accounts.

3.           No  claim  shall  lie in  respect  of  any  breach  of the  Sellers
             Warranties  to the extent that the same is capable of remedy unless
             the   Purchaser   shall  first  afford  the  Sellers  a  reasonable
             opportunity  to remedy the  breach  complained  of in a  reasonable
             fashion.

4.           The  aggregate  liability of the Sellers in relation to the Sellers
             Warranties  shall in any  event be  restricted  to the value of the
             Holdback  Shares as at the date of Completion.  The recourse of the
             Purchaser  in respect  of any claim  under the  Sellers  Warranties
             shall be limited  to the  exercise  of its rights  under the Eighth
             Schedule in respect of the Holdback Shares.

5.           The amount of any  settlement  made by each Seller to the Purchaser
             in  respect  of any claim  under the  Sellers  Warranties  shall be
             deemed  a  reduction   dollar  for  dollar  in  the  value  of  the
             consideration payable to the Sellers under this Agreement.

6.           Nothing in this Seventh  Schedule shall operate to limit or exclude
             the liability of the Sellers for fraud or misrepresentation.

7.           Any  settlement  made by the Sellers  pursuant to the provisions of
             this Schedule shall be made in accordance  with, and be subject to,
             the provisions of the Eighth Schedule.

 




                               THE EIGHTH SCHEDULE

                                    HOLDBACK

1.1          On  Completion,  each Seller  shall be deemed to have  directed the
             Purchaser  to  withhold  from  delivery  ten per cent  (10%) of the
             Consideration  Shares  issued to such Seller  against the  Seller's
             liabilities under the Seller's Warranties. The Consideration Shares
             withheld  are herein  referred  to as the  "Holdback  Shares".  The
             Holdback  Shares  shall be deemed to be issued to the  Sellers  but
             held by the Purchaser  subject to the terms and  conditions set out
             below.  Holdback Shares shall be considered as issued share capital
             of the Purchaser and shall have the rights set out below.

1.2          All  dividends  and  distributions  (other than cash  dividends and
             distributions)  made by the Purchaser  with respect to the Holdback
             Shares will be held by the Purchaser with the other Holdback Shares
             as  provided  herein as  additional  assets of the  withholding  to
             satisfy any claims arising from a breach of the Sellers  Warranties
             ("a Claim"). Cash dividends and distributions, if any, will be made
             by the  Purchaser  to each  Seller,  pro  rata  according  to their
             respective interests in the Holdback Shares.

1.3          If a meeting or written  action of  shareholders  of the  Purchaser
             occurs while the  provisions  of this Schedule are still in effect,
             the  Purchaser  shall  promptly  send to each Seller  copies of any
             notices,  proxies  and  proxy  materials  in  connection  with such
             meeting or written  action.  At the time of any such  meeting,  the
             Purchaser shall, if deemed necessary by any of the Sellers, execute
             and  deliver  a proxy  authorising  each  Seller  to vote the whole
             number of their Holdback Shares (eliminating any fractions).

2.           The withholding of the Holdback Shares hereunder is for the purpose
             of providing a source of  indemnification  to the Purchaser and the
             other members of the  Purchaser's  Group  pursuant to the terms and
             conditions of this Agreement, from and against all Claims.

3.1          The Holdback  Shares shall be retained by the  Purchaser  until the
             earlier to occur of (i) the delivery by Pricewaterhouse Coopers LLP
             of its  report  on the  Purchaser's  financial  statements  for the
             fiscal year ended 30 June 1999 or (ii) 31 March 2000 ("the Holdback
             Termination  Date") when,  subject to Clauses 3.2 and 3.3 below the
             Holdback Shares, less the Payment Shares (as defined below) if any,
             shall be distributed to the Sellers.

3.2          The  Holdback  Shares shall not be  distributed  to a Seller on the
             Holdback Termination Date in the event that:

             3.2.1       a Seller has either  agreed  liability for a Claim or a
                         counsel  appointed  pursuant  to  Clause  4  below  has
                         determined  the  amount of a Claim  and in either  case
                         such Claim has not been satisfied in full; and/or

             3.2.2       the  Purchaser  has made a Claim  which is  subject  to
                         determination in accordance with Clause 4 below.



4.1          If the  Purchaser  and/or the Company has a Claim the Purchaser (on
             its own behalf  and/or on the behalf of the Company) will deliver a
             written notice thereof to the Sellers  Representative  (which shall
             be valid  notice to all  Sellers) (a "Notice of Claim") and setting
             forth the number of Holdback Shares  necessary to satisfy the claim
             in question, which will be determined by dividing (x) the amount of
             such  Claim by (y) the value of one of the  Holdback  Shares on the
             date of Completion (the "Payment Shares").  A good faith failure to
             state  correctly in a Notice of Claim the full amount of the damage
             suffered by the  Purchaser  and/or the Company  will not  prejudice
             their claim for damages in respect of such Claim, and the Purchaser
             may deliver an additional  Notice of Claim as provided  herein with
             respect to any amount of  damages  not stated (in good  faith) in a
             previous Notice of Claim.

4.2          If the Sellers  object (and for this purpose an objection will only
             be valid if it is made by Seller(s)  representing 75% of the Shares
             formerly  held) to such Notice of Claim (whether as to liability or
             the amount claimed), the Seller's  Representative will give written
             notice to the Purchaser, within 7 Business Days, of receipt of such
             Notice of Claim  advising the Purchaser of its objection (a "Notice
             of  Objection").  If no Notice of  Objection  is received  from the
             Sellers'  Representative  by the Purchaser  within such period (and
             time shall be of the essence), the Purchaser will effect payment of
             the  amount of such  Claim as  provided  in Clause 5 below.  If the
             Seller's  Representative delivers a Notice of Objection within such
             period (and time shall be of the  essence),  the  Purchaser and the
             Sellers will  promptly  meet and use their best  endeavours in good
             faith to settle the dispute.  If the  Purchaser and the Sellers are
             able to settle the dispute,  in whole or in part,  they will record
             such settlement in writing and the Purchaser will effect payment of
             that Claim (or other agreed  amount) as provided in Clause 5 below.
             If the Purchaser and Sellers are unable to reach  agreement  within
             10 Business  Days after the  delivery  of the Notice of  Objection,
             then the dispute shall be referred to the determination of a Senior
             Commercial  Counsel/Independent  Accountant ("the Appointee").  The
             Appointee shall be asked whether in his opinion that Claim would on
             the balance of  probability be likely to succeed and the quantum of
             such Claim. Such opinion to be available within 10 Business Days of
             submission  of  argument  from  all  parties  such  argument  to be
             provided to the  Appointee  by all parties no later than 5 Business
             Days following the day of the Appointee's  appointment.  Time shall
             be of the essence.

4.3          If the  Purchaser  is  entitled  to  any  damages  pursuant  to the
             determination  of the Appointee in accordance with Clause 4.2 above
             payment of the amount of such  damages  which is  specified in such
             determination  will be made in the  manner  prescribed  in Clause 5
             below.  Notwithstanding the foregoing,  the Purchaser shall deliver
             to the Sellers a notice  specifying  the amount and the  equivalent
             number of Payment  Shares which will be deducted  from the Holdback
             Shares.

5.           If the Purchaser is entitled  pursuant to Clause 4 above to receive
             damages in respect of a Claim,  the  Purchaser  will  exchange  the
             certificate  representing  the  Holdback  Shares  for a  new  share
             certificate representing a number of shares of the Purchaser (which
             will remain Holdback Shares) equal to the number of Holdback Shares
             previously held by the Purchaser less the number of Payment Shares.
             The number of Holdback  Shares  attributable to each Seller will be
             reduced  (and the number of  Payment  Shares  determined)  pro rata
             (subject to  appropriate  adjustment  in respect of fractions) to a
             Seller's  entitlement  to  Consideration  Shares  as set out in the
             First Schedule.


                               THE NINTH SCHEDULE

                             SPECIFIC CONTINGENCIES

1.           The following are identified as specific  contingencies in relation
             to the acquisition of the Shares:

             (i)         In or about October 1998 five employees of Biostat were
                         made redundant for economic  reasons.  Liability to the
                         Company may arise out of the  inadequacy of the reasons
                         and/or the redundancy  letters sent to those  employees
                         should those  former  employees  initiate  proceedings:
                         FF600,000;

             (ii)        The  employment by Biostat of Dr. Kharat was terminated
                         in  or  about   September   1997.  Dr.  Kharat  brought
                         proceedings  against  Biostat  inter alia for  wrongful
                         dismissal and termination indemnities: FF475,000;

             (iii)       During  1998  Biostat  paid fees to a number of doctors
                         which fees are  required to be reported on a particular
                         annual  return.   Certain  doctors  were  employees  of
                         clinics or  hospitals  and in those  circumstances  any
                         payment  to those  doctors  would be  subject to proper
                         payroll  taxes.  Liability  to account for such payroll
                         taxes falls on Biostat: FF200,000

             (iv)        Droit et Pharmacie  publishes two reviews;  the persons
                         who are responsible for producing the articles for such
                         publications  may claim the  status of  journalist.  In
                         this event and were they to seek  termination  of their
                         employment  agreements  with that company they would be
                         entitled to certain termination indemnities: FF950,000;

             (v)         Proceedings  have been  issued  against  Biostat by Mr.
                         Boinet  in or about  July 1998 in which a claim is made
                         against  the Company for breach of patent in respect of
                         an  electronic  pill box. Mr.  Boinet inter alia claims
                         damages against Biostat: FF600,000

             (vi)        Proceedings  have been  issued  against  Biostat by Mr.
                         Maraschli  in which it is  claimed  inter alia that the
                         software   installed  by  Biostat  is  defective.   Mr.
                         Maraschli  claims against the Company damages  together
                         with  repayment  of the sum paid by him to the Company:
                         FF250,000;

             (vii)       Proceedings   have  been  issued  against   Biostat  by
                         Syndicate  National des  Gynecologues  Obstetriciens de
                         France (SNGOF) by way of  counterclaim  for damages and
                         maintenance obligations: FF800,000;

             (viii)      Proceedings  have been issued against Biostat by Solvay
                         Pharma by way of counterclaim for wrongful  termination
                         of contract by Biostat.  Solvay Pharma  claims  damages
                         and costs: FF186,000.

             together or individually the "Specific Contingencies".

2.           The Sellers jointly and severally  indemnify the Purchaser  against
             any   liability   suffered  or  incurred  by  the  Purchaser  as  a
             consequence of or arising out of any of the Specific Contingencies.

3.           On  Completion,  each Seller  shall be deemed to have  directed the
             Purchaser to withhold  from  delivery in  aggregate  an  additional
             fifteen per cent of the Consideration  Shares issued to such Seller
             against  the  Sellers  liabilities  in  relation  to  the  Specific
             Contingencies  identified above. The Consideration  Shares withheld
             pursuant hereto are herein referred to as the "Additional  Holdback
             Shares".

4.           The  provisions  of  Clauses  1.2 to 5  (inclusive)  of the  Eighth
             Schedule  shall apply to this Ninth  Schedule as if set out in full
             herein provided that the Additional Holdback Shares may be retained
             by  the   Purchaser   until  31  March  2000  unless  the  Specific
             Contingency is still outstanding in which event the relevant shares
             may be  withheld  for a  further  year  (the  "Additional  Holdback
             Termination Date" and the Sellers will continue to be liable to the
             Purchaser hereunder until that date).




SIGNED by                       )
in the presence of:             )        /s/ Herve Laurent
Denis Polack, Lawyer


SIGNED by                       )
in the presence of:             )       /s/ Philippe Conquet
Denis Polack, Lawyer


SIGNED by                       )
in the presence of              )        /s/ Christian Haas, for COMIR
Denis Polack, Lawyer


SIGNED by                       )
in the presence of:             )        /s/ Christian Haas, for SENLISIENNE de
Denis Polack, Lawyer                     PORTEFEUILLE


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     B. Chahid-Nourai


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     FINANVAL


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     Caroline Conquet


SIGNED by                       )
in the presence of:             )        /s/ Herve Laurent, as attorney for
Denis Polack, Lawyer                     Karine Laurent


SIGNED by                       )
in the presence of:             )        /s/ Herve Laurent, as attorney for
Denis Polack, Lawyer                     Valerie Laurent




SIGNED by                       )
for and on behalf of            )
PAREXEL INTERNATIONAL           )
CORPORATION                     )
in the presence of:             )        /s/ Barry R. Philpott
Richard Elphick
Lawrence Graham
190 Strand
WC2R 1JN


SIGNED by                       )
in the presence of:             )        /s/ Herve Laurent, as attorney for
Denis Polack, Lawyer                     Caroline Laurent


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     Yvon Leroux


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     Succession de Francois Baur


SIGNED by                       )
in the presence of:             )        /s/ Philippe Conquet, as attorney for
Denis Polack, Lawyer                     Charles Baur


<PAGE>
EXHIBIT 4.1
   


                                                                Draft of 3/25/99

                          REGISTRATION RIGHTS AGREEMENT

         AGREEMENT  dated as of  March  31,  1999  among  PAREXEL  International
Corporation,  a Massachusetts  corporation  (the "Company") and the stockholders
listed on Schedule A hereto  (individually,  a "Stockholder,"  and collectively,
the "Stockholders").

                              W I T N E S S E T H:

         WHEREAS,  pursuant to the Share Acquisition Agreement dated as of March
31,  1999 (the  "Acquisition  Agreement")  among  the  Company,  Herve  Laurent,
Philippe  Conquet and the other parties named therein,  the Company will acquire
all of the outstanding  capital stock of Group PharMedicom S.A.  ("PharMedicom")
and PharMedicom will become a wholly-owned subsidiary of the Company;

         WHEREAS, in connection therewith,  the Stockholders will receive shares
of Common Stock of the Company (the "Shares") that are being issued  pursuant to
an exemption from registration under the Securities Act; and

         WHEREAS,  the Company and the  Stockholders  wish to set forth  certain
rights and obligations with regard to the registration of the Shares pursuant to
the Securities Act;

         NOW, THEREFORE, the parties hereto agree as follows:

         1.       Certain Definitions.  As used in this Agreement, the following
                  terms shall have the following respective meanings:

                  "Commission"  shall  mean the  United  States  Securities  and
                  Exchange  Commission or any other  federal  agency at the time
                  administering the Securities Act.

                  "Shares"  shall mean the shares of Common Stock of the Company
                  issued to the  Stockholders on even date herewith  pursuant to
                  the Acquisition Agreement.

                  "Common Stock" shall mean the common stock, $.01 par value, of
                  the Company,  as constituted as of the date of this Agreement.
                  "Exchange  Act"  shall  mean  the  United  States   Securities
                  Exchange Act of 1934,  as amended,  or any  successor  federal
                  statute,  and the  rules  and  regulations  of the  Commission
                  thereunder, all as the same shall be in effect at the time.

                  "Registration  Expenses"  shall mean the expenses so described
                  in Section 9.

                  "Securities  Act" shall mean the United States  Securities Act
                  of 1933, as amended, or any successor federal statute, and the
                  rules and regulations of the Commission thereunder, all as the
                  same shall be in effect at the time.

                  "Selling  Expenses"  shall mean the  expenses so  described in
                  Section 8.

         2.       Securities Act Matters. The Stockholders acknowledge and agree
                  that the Shares have not been registered  under the Securities
                  Act, in reliance on the  provisions  of Regulation S under the
                  Securities  Act, or under the securities laws of any state, in
                  reliance upon certain exemptive provisions of such state laws.
                  The   Stockholders   recognize   and   acknowledge   that  the
                  availability  of  Regulation  S and claims of  exemption  from
                  state  laws  are  based,  in  part,  upon  the   Stockholders'
                  representations  contained in the Acquisition Agreement and in
                  each Stockholder's New Owner  Questionnaire  (attached as page
                  12 of this Agreement.  The Stockholders  further recognize and
                  acknowledge  that,  because the Shares were issued pursuant to
                  Regulation S and the Shares were not registered  under federal
                  and state  laws,  the Shares are not  presently  eligible  for
                  public resale,  and may only be resold in the future  pursuant
                  to the  provisions  of  Regulation S, pursuant to an effective
                  registration  statement  under  the  Securities  Act  and  any
                  applicable  state  securities  laws,  or  pursuant  to a valid
                  exemption   from   such   registration    requirements.    The
                  Stockholders  further  acknowledge and agree that they may not
                  engage in  hedging  transactions  with  respect  to the Shares
                  unless in compliance with the Securities Act. The Stockholders
                  recognize  and  acknowledge  that Rule 144 (which  facilitates
                  routine sales of  securities in accordance  with the terms and
                  conditions   of  that  Rule,   including   a  holding   period
                  requirement)  is not now  available  for resale of the Shares,
                  and the  Stockholders  recognize and acknowledge  that, in the
                  absence of the  availability of Rule 144, a sale pursuant to a
                  claim of exemption from registration  under the Securities Act
                  would require  compliance  with some other exemption under the
                  Securities  Act,  which may not be available for resale of the
                  Shares.  The  Stockholders  recognize  and  acknowledge  that,
                  except as set forth in this Agreement, the Company is under no
                  obligation  to  register  the Shares,  either  pursuant to the
                  Securities Act or the securities laws of any state.

         3.       Restrictive  Legend.  Each  certificate   representing  Shares
                  shall,  except as  otherwise  provided in this Section 3 or in
                  Section  4, be stamped or  otherwise  imprinted  with a legend
                  substantially in the following form:

                  "The  securities  represented  hereby have not been registered
                  under the Securities Act of 1933, as amended (the  "Securities
                  Act"),  and the sale,  transfer or other  disposition  of such
                  securities  is  prohibited   except  in  accordance  with  the
                  provisions of Regulation S, pursuant to registration under the
                  Securities Act and the securities laws of certain  states,  or
                  pursuant to an  available  exemption  from such  registration.
                  Hedging  transactions  involving  the  securities  represented
                  hereby  may not be  conducted  unless in  compliance  with the
                  Securities Act."

         Such  certificates  shall not bear such  legend  if in the  opinion  of
         counsel satisfactory to the Company the securities  represented thereby
         may be publicly sold without  registration  under the Securities Act or
         if such  securities  have been  sold  pursuant  to Rule 144,  any other
         exemption  under  the  Securities  Act  or  an  effective  registration
         statement.

         4.       Notice of Proposed Transfer. Prior to any proposed transfer of
                  any Shares  before the  expiration of the  applicable  holding
                  period  set forth in Rule 144,  each  Stockholder  shall  give
                  written  notice to the Company of his intention to effect such
                  transfer.  Prior to any  registration  statement  described in
                  Section 5 becoming effective,  each such notice shall describe
                  the manner of the proposed  transfer  and, if requested by the
                  Company,  shall  be  accompanied  by  an  opinion  of  counsel
                  satisfactory  to the Company to the effect  that the  proposed
                  transfer  may  be  effected  without  registration  under  the
                  Securities Act, whereupon the Stockholder shall be entitled to
                  transfer  such  security in  accordance  with the terms of his
                  notice. Each certificate for Shares transferred as above shall
                  bear the  legend  set forth in  Section  3,  except  that such
                  certificate shall not bear such legend if (i) such transfer is
                  in  accordance  with the  provisions of Rule 144 (or any other
                  rule  permitting  public sale without  registration  under the
                  Securities  Act),  or (ii)  such  transfer  is  pursuant  to a
                  registration under the Securities Act, or (iii) the opinion of
                  counsel  referred to above is to the  further  effect that the
                  transferee  and  any  subsequent  transferee  (other  than  an
                  affiliate of the Company)  would be entitled to transfer  such
                  securities  in a public sale  without  registration  under the
                  Securities Act.

         5.       Required  Registration.  The Company  agrees to use reasonable
                  efforts to (i) cause a registration statement on Form S-3 (the
                  "Registration  Statement") or any successor form thereto under
                  the  Securities  Act  relating to the resale of fifty  percent
                  (50%) of the  Shares  to be  filed no later  than the 10th day
                  following  the  date on  which  the  Company  files  with  the
                  Commission  its Annual Report on Form 10-K for the fiscal year
                  ending  June  30,  1999;  and  (ii)  cause  the   Registration
                  Statement to become effective as soon as practicable after the
                  filing  thereof  and  thereafter  remain  effective  until the
                  earlier of (A) one year after  Completion  (as  defined in the
                  Acquisition  Agreement) or (B) the sale of all Shares  covered
                  thereby. Anything to the contrary herein notwithstanding,  the
                  Company  shall not be required to take any action to cause any
                  registration   statement  to  be  declared  effective  by  the
                  Commission at any time prior to the publication by the Company
                  of   financial   results   including   at   least   30   days'
                  post-Completion  combined operating results of the Company and
                  PharMedicom,  and the Company may suspend  sales in accordance
                  with  Section 7 at any time under the  Registration  Statement
                  immediately  upon written notice to the  Stockholders at their
                  last known  address,  for any of the  reasons and for the time
                  periods set forth in Section 7.

         6.       Registration  Procedures.  If and when the Company is required
                  by the  provisions of Section 5 to use  reasonable  efforts to
                  effect the  registration  of any Shares  under the  Securities
                  Act, the Company will, as expeditiously as possible:

                  (a)      prepare and file with the Commission  such amendments
                           and supplements to the  Registration  Statement,  and
                           the prospectus used in connection  therewith,  as may
                           be necessary to comply with the Securities Act;

                  (b)      furnish to the Stockholders  such number of copies of
                           the  Registration  Statement  and each  amendment and
                           supplement thereto (in each case including  exhibits)
                           and the prospectus  included therein  (including each
                           preliminary   prospectus)  as  they   reasonably  may
                           request in order to  facilitate  the  public  sale or
                           other  disposition  of  the  Shares  covered  by  the
                           Registration Statement;

                  (c)      register  or  qualify  the  Shares   covered  by  the
                           applicable    registration    statement   under   the
                           securities  or "blue  sky" laws of the  jurisdictions
                           where  the  Company  is   currently   registered   or
                           qualified or its Common Stock is currently registered
                           or qualified for resale and provide each  Stockholder
                           with a list of such jurisdictions; provided, however,
                           that the  Company  shall not for any such  purpose be
                           required to qualify generally to transact business as
                           a foreign corporation in any jurisdiction where it is
                           not so qualified or to consent to general  service of
                           process in any such jurisdiction;

                  (d)      have the Shares covered by the Registration Statement
                           quoted or traded on the NASDAQ National Market or any
                           other   quotation   system  or  exchange   where  the
                           Company's Common Stock is then quoted or traded; and

                  (e)      promptly  notify each  Stockholder (at his last known
                           address)   (i)  of   the   effective   date   of  the
                           Registration   Statement   and  the  date   when  any
                           post-effective    amendment   to   the   Registration
                           Statement becomes  effective,  (ii) of any stop order
                           or  notification  from the  Commission  or any  other
                           jurisdiction    as   to   the   suspension   of   the
                           effectiveness of the Registration Statement, or (iii)
                           of the institution and ending of any suspension under
                           Section 7.

         7.       Suspension.

                  (a)      The rights of the  Stockholders  to resell the Shares
                           pursuant  to  this  Agreement  and  the  Registration
                           Statement  may be  suspended  by the  Company  on the
                           occurrence of any of the following events:

                           (i)      the Board of  Directors  of the  Company has
                                    voted to  conduct a public  offering  or the
                                    Company   is   holding   or  has   held   an
                                    "organizational"   or  "all  hands"  meeting
                                    relating  to a  public  offering,  whichever
                                    first occurs;

                           (ii)     the  Company  is  about  to  make  a  public
                                    disclosure  of  information  of  a  material
                                    nature;

                           (iii)    there  then  exists   material,   non-public
                                    information  relating  to  the  Company  the
                                    disclosure of which, in the determination of
                                    its Board of Directors,  would not be in the
                                    interests of the Company or its stockholders
                                    during  that time and which the  Company  is
                                    not  otherwise,   after   consultation  with
                                    counsel, obligated to disclose; or

                           (iv)     the  Company is engaged in any  activity  or
                                    transaction   at  any  time  that,   in  the
                                    determination  of its  Board  of  Directors,
                                    would be  materially  adversely  affected by
                                    the continued compliance with this Agreement
                                    or the continued  distribution of the Shares
                                    by the Stockholders.

                  (b)      The Company shall use reasonable  efforts to minimize
                           the length of any suspension under Section 7(a).

                  (c)      The period  during which the  Registration  Statement
                           filed pursuant to Section 5 remains  effective  shall
                           be extended  by any period  during  which  resales of
                           Shares  pursuant to the  Registration  Statement  are
                           suspended pursuant to this Section 7.

         8.       Expenses.  All  expenses  incurred by the Company in complying
                  with   Section   5,   including,   without   limitation,   all
                  registration  and filing  fees,  printing  expenses,  fees and
                  disbursements  of counsel and independent  public  accountants
                  for the Company, fees and expenses incurred in connection with
                  complying  with state  securities or "blue sky" laws,  fees of
                  the National Association of Securities Dealers, Inc., transfer
                  taxes,  fees of transfer agents and  registrars,  and costs of
                  issuance,  but  excluding  any  Selling  Expenses,  are called
                  "Registration  Expenses".  All underwriting discounts (if any)
                  and selling  commissions  applicable to the sale of the Shares
                  covered  by  the  Registration   Statement,  as  well  as  all
                  professional  service fees incurred by the  Stockholders,  are
                  called "Selling Expenses".

                  All Selling Expenses shall be borne by the  Stockholders.  The
                  Company will pay all Registration  Expenses in connection with
                  the  preparation  and  filing of the  Registration  Statement;
                  provided,  however,  that in the event  that the  Registration
                  Statement  is  withdrawn  or  abandoned  for any reason at the
                  request of the Stockholders,  then the Stockholders shall bear
                  all Registration  Expenses paid or incurred in connection with
                  such abandoned Registration  Statement.  The Company shall not
                  be  obligated  to pay any  reasonably  verifiable  increase in
                  Registration  Expenses in connection  with the preparation and
                  filing  of the  Registration  Statement  if  the  Registration
                  Statement  is  delayed  for any  reason at the  request of the
                  Stockholders;  such increased  Registration  Expenses shall be
                  borne by the Stockholders.

         9.       Indemnification and Contribution.

                  (a)      In  connection  with the  registration  of the Shares
                           under the  Securities  Act pursuant to Section 5, the
                           Company  will   indemnify   and  hold  harmless  each
                           Stockholder,   each   underwriter   of  such   Shares
                           thereunder  and  each  other  person,   if  any,  who
                           controls such  Stockholder or underwriter  within the
                           meaning of the  Securities  Act,  against any losses,
                           claims, damages or liabilities,  joint or several, to
                           which such  Stockholder,  underwriter  or controlling
                           person may become subject under the  Securities  Act,
                           Exchange  Act,  state  securities  laws or otherwise,
                           insofar   as  such   losses,   claims,   damages   or
                           liabilities (or actions in respect thereof) arise out
                           of or are  based  upon (i) any  untrue  statement  or
                           alleged  untrue  statement of material fact contained
                           in  the  Registration   Statement,   any  preliminary
                           prospectus or final prospectus  contained therein, or
                           any  amendment  or  supplement   thereto,   (ii)  the
                           omission  or  alleged  omission  of a  material  fact
                           required to be stated  therein or  necessary  to make
                           the  statements  therein not  misleading or (iii) any
                           violation by the Company or its agents of any rule or
                           regulation  promulgated  under  the  Securities  Act,
                           Exchange Act or state  securities  laws applicable to
                           the  Company or its agents and  relating to action or
                           inaction  required of the Company in connection  with
                           such  registration,  and the Company  will  reimburse
                           each such Stockholder, each such underwriter and each
                           such  controlling  person  for  any  legal  or  other
                           expenses  reasonably  incurred by them in  connection
                           with investigating or defending any such loss, claim,
                           damage,  liability  or action,  as such  expenses are
                           incurred;  provided,  however,  that the Company will
                           not be liable  in any such case if and to the  extent
                           that any such loss, claim, damage or liability arises
                           out  of or is  based  upon  an  untrue  statement  or
                           alleged  untrue  statement  or  omission  or  alleged
                           omission  so  made  based  upon  written  information
                           furnished  by or for any such  Stockholder,  any such
                           underwriter   or   any   such   controlling    person
                           specifically for use in the Registration Statement.

                  (b)      In  connection  with the  registration  of the Shares
                           under the  Securities Act pursuant to Section 5, each
                           Stockholder  will  indemnify  and hold  harmless  the
                           Company,  each  person,  if  any,  who  controls  the
                           Company  within the  meaning of the  Securities  Act,
                           each   officer   of  the   Company   who   signs  the
                           Registration Statement, each director of the Company,
                           each  underwriter  and each person who  controls  any
                           underwriter within the meaning of the Securities Act,
                           against all losses,  claims,  damages or liabilities,
                           joint  or  several,  to  which  the  Company  or such
                           officer, director,  underwriter or controlling person
                           may  become  subject  under  the  Securities  Act  or
                           otherwise, insofar as such losses, claims, damages or
                           liabilities (or actions in respect thereof) arise out
                           of  or  are  based  upon  (i)  the  failure  of  such
                           Stockholder  to comply with the provisions of Section
                           12 herein or (ii) any  untrue  statement  or  alleged
                           untrue  statement of any material  fact  contained in
                           the   Registration    Statement,    any   preliminary
                           prospectus or final prospectus  contained therein, or
                           any  amendment or  supplement  thereto,  or (iii) the
                           omission  or  alleged  omission  to state  therein  a
                           material  fact  required  to  be  stated  therein  or
                           necessary   to  make  the   statements   therein  not
                           misleading,  and will  reimburse the Company and each
                           such officer,  director,  underwriter and controlling
                           person  for any  legal or other  expenses  reasonably
                           incurred by them in connection with  investigating or
                           defending any such loss, claim, damage,  liability or
                           action,  as such  expenses  are  incurred,  provided,
                           however,   that  such   Stockholder  will  be  liable
                           hereunder  in any such case if and only to the extent
                           that any such loss, claim, damage or liability arises
                           out  of or is  based  upon  an  untrue  statement  or
                           alleged  untrue  statement  or  omission  or  alleged
                           omission made in reliance upon and in conformity with
                           written  information  pertaining to such Stockholder,
                           furnished by or for such Stockholder specifically for
                           use in the Registration Statement.

                  (c)      Promptly  after  receipt  by  an  indemnified   party
                           hereunder  of  notice  of  the  commencement  of  any
                           action,  such indemnified  party shall, if a claim in
                           respect   thereof   is  to  be   made   against   the
                           indemnifying party hereunder, notify the indemnifying
                           party in  writing  thereof,  but the  omission  so to
                           notify the  indemnifying  party  shall not relieve it
                           from  any  liability   which  it  may  have  to  such
                           indemnified party other than under this Section 9 and
                           shall only relieve it from any liability which it may
                           have to such indemnified party under this Section 9if
                           and  to  the   extent  the   indemnifying   party  is
                           prejudiced by such omission.  In case any such action
                           shall be brought against any indemnified party and it
                           shall   notify   the   indemnifying   party   of  the
                           commencement thereof, the indemnifying party shall be
                           entitled  to  participate  in and,  to the  extent it
                           shall  wish,  to assume  and  undertake  the  defense
                           thereof with counsel  satisfactory to reasonably such
                           indemnified   party,   and,  after  notice  from  the
                           indemnifying  party to such indemnified  party of its
                           election  so to  assume  and  undertake  the  defense
                           thereof and the approval by the indemnified  party of
                           the counsel chosen by the  indemnifying  party (which
                           approval  shall  not  be  unreasonably   withheld  or
                           delayed),  the indemnifying party shall not be liable
                           to such  indemnified  party under this  Section 9 for
                           any  legal  expenses  subsequently  incurred  by such
                           indemnified  party in  connection  with  the  defense
                           thereof other than reasonable  costs of investigation
                           and of liaison with  counsel so  selected;  provided,
                           however,  that, if the  defendants in any such action
                           include   both   the   indemnified   party   and  the
                           indemnifying  party  and  if  the  interests  of  the
                           indemnified   party   reasonably  may  be  deemed  to
                           conflict  with  the  interests  of  the  indemnifying
                           party, the indemnified  party shall have the right to
                           select one separate  counsel and to assume such legal
                           defenses and otherwise to  participate in the defense
                           of such action, with the reasonable expenses and fees
                           of  such  separate   counsel  and  other   reasonable
                           expenses   related  to  such   participation   to  be
                           reimbursed by the indemnifying party as incurred.  No
                           indemnifying  party will consent to entry of judgment
                           or enter into any settlement that does not include as
                           an  unconditional  term  thereof  the  giving  by the
                           claimant or plaintiff to such indemnified  party of a
                           release from all liability with respect to such claim
                           or litigation.

                  (d)      In  order   to   provide   for  just  and   equitable
                           contribution  to joint liability in any case in which
                           either (i) a Stockholder  exercises rights under this
                           Agreement  and  makes  a  claim  for  indemnification
                           pursuant  to  this  Section  9 but  it is  judicially
                           determined  (by  the  entry  of a final  judgment  or
                           decree by a court of competent  jurisdiction  and the
                           expiration  of time to  appeal  or the  denial of the
                           last right of appeal) that such  indemnification  may
                           not be enforced in such case notwithstanding the fact
                           that this Section 9 provides for  indemnification  in
                           such case, or (ii) contribution  under the Securities
                           Act may be required on the part of the Stockholder in
                           circumstances for which  indemnification  is provided
                           under this  Section  9; then,  and in each such case,
                           the Company and the  Stockholders  will contribute to
                           the aggregate losses,  claims, damages or liabilities
                           to which they may be subject (after contribution from
                           others) in  proportion  to the relative  fault of the
                           Company,  on the one hand, and the  Stockholders,  on
                           the other hand; provided,  however, that, in any such
                           case,  no  person  or  entity  guilty  of  fraudulent
                           misrepresentation  (within  the  meaning  of  Section
                           10(f)of  the  Securities  Act)  will be  entitled  to
                           contribution  from any  person or entity  who was not
                           guilty of such fraudulent misrepresentation.

                  (e)      The  indemnities  provided  in this  Section  9 shall
                           survive the transfer of any Shares by a Stockholder.


         10.      Reports Under Securities  Exchange Act of 1934. With a view to
                  making  available to each of the  Stockholders the benefits of
                  Rule 144  promulgated  under the  Securities Act and any other
                  rule or regulation  thereunder that may at any time permit any
                  such  Stockholder  to sell  securities  of the  Company to the
                  public without registration, the Company agrees to:

                  (a)      make and keep public information available,  as those
                           terms are understood and defined in Rule 144;

                  (b)      maintain the  registration  of its Common Stock under
                           Section 12 of the Exchange Act;

                  (c)      file  in  a  timely  manner  all  reports  and  other
                           documents   required   of  the   Company   under  the
                           Securities Act and the Exchange Act; and

                  (d)      furnish  to any  such  Stockholder,  so  long  as the
                           Stockholder owns any Shares,  forthwith upon request:
                           (i) a written  statement  by the Company  that it has
                           complied with the reporting requirements of Rule 144,
                           (ii) a copy of the most  recent  annual or  quarterly
                           report of the  Company  and such  other  reports  and
                           documents  so filed by the  Company;  and (iii)  such
                           other  information as may be reasonably  requested in
                           availing the  Stockholder  of any rule or  regulation
                           under the Securities Act which permits the selling of
                           any such securities without  registration or pursuant
                           to such form.

                  Notwithstanding  anything in this  Agreement to the  contrary,
                  the  Company's  obligations   identified  in  subsections  (a)
                  through (d) of this Section 10 shall cease at such time as the
                  Stockholders  may resell their Shares pursuant to Rule 144(k),
                  if  and  to the  extent  that  the  fulfillment  of  any  such
                  obligation  is not a  condition  to the  resale of the  Shares
                  pursuant to Rule 144(k).

         11.      Changes in Common  Stock.  If,  and as often as,  there is any
                  change  in the  Common  Stock by way of a stock  split,  stock
                  dividend,  combination  or  reclassification,   or  through  a
                  merger, consolidation,  reorganization or recapitalization, or
                  by any other means,  appropriate  adjustment  shall be made in
                  the  provisions  hereof  so that  the  rights  and  privileges
                  granted hereby shall continue with respect to the Shares as so
                  changed.

         12.      Stockholder's  Conduct.  With  respect  to any sale of  Shares
                  covered  by  the  Registration  Statement,   each  Stockholder
                  understands and agrees as follows:

                  (a)      Each    Stockholder   will   carefully   review   the
                           information   concerning   him   contained   in   the
                           Registration  Statement and will promptly  notify the
                           Company  if  such  information  is not  complete  and
                           accurate in all material  respects,  including having
                           properly  disclosed  any  position,  office  or other
                           material  relationship  within the past  three  years
                           with the Company or its affiliates;

                  (b)      Each  Stockholder  agrees to sell  Shares only in the
                           manner  set forth in (i) the  Registration  Statement
                           (or in  compliance  with Section 4 hereof),  (ii) the
                           Affiliate  Agreement  (as defined in the  Acquisition
                           Agreement)  (if the  Stockholder  is a party thereto)
                           and (iii) Section 13 of this Agreement;

                  (c)      Each   Stockholder   agrees   to   comply   with  the
                           anti-manipulation  rules  under the  Exchange  Act in
                           connection  with purchases and sales of securities of
                           the   Company   during  the  time  the   Registration
                           Statement remains effective;

                  (d)      Each  Stockholder  agrees  to only  sell  Shares in a
                           jurisdiction   after  counsel  for  the  Company  has
                           advised  that  such  sale is  permissible  under  the
                           applicable state securities or "blue sky" laws;

                  (e)      Each Stockholder agrees to comply with the prospectus
                           delivery requirements of the Securities Act;

                  (f)      Each Stockholder  agrees to notify the Company of any
                           and all planned sales and  completed  sales of Shares
                           in accordance with the terms of this Agreement; and

                  (g)      Each  Stockholder  agrees to suspend sales during the
                           periods  when sales are to be  suspended  pursuant to
                           Section 7.

                  (h)      In connection  with the  registration  of the Shares,
                           each  Stockholder  will  furnish  to the  Company  in
                           writing  such  information  requested  by the Company
                           with respect to himself and the proposed distribution
                           by him as shall be  necessary in order to comply with
                           federal and applicable state securities laws.

                  (i)      Each Stockholder hereby agrees that he will not sell,
                           exchange,  transfer,  pledge,  dispose  or  otherwise
                           reduce his risk  relative to any Shares  owned by him
                           during the period which begins on the date hereof and
                           ends at such time as the Company  publicly  announces
                           financial  results  covering  at  least  30  days  of
                           combined  operations of the Company and  PharMedicom.
                           The  Company,  at  its  discretion,  may  cause  stop
                           transfer  orders to be placed with its transfer agent
                           with  respect to the  certificates  representing  the
                           Shares;  provided,  however,  that such stop transfer
                           orders shall be consistent with the other  provisions
                           of this Agreement.

13.      Selling Procedures.

                  (a)      Each  Stockholder  will  notify  the  Company  of his
                           intention  to  sell  Shares  under  the  Registration
                           Statement  not  fewer  than  five  nor  more  than 15
                           business days prior to the expected date of such sale
                           by faxing the "Takedown  Request"  attached hereto as
                           Exhibit A to:

                                 Carl F. Barnes
                       Vice President and General Counsel
                        PAREXEL International Corporation
                                 195 West Street
                          Waltham, Massachusetts 02451
                          Phone: (781) 487-9904 x 4158
                            Facsimile: (781) 890-4813

During this  period,  the Company will review the  prospectus  to determine if a
suspension  pursuant to Section 7 is  necessary or  appropriate.  If the Company
does not notify  the  Stockholder  of a  suspension  pursuant  to Section 7, the
Stockholder  may conclude the proposed  sale,  on the proposed  date of sale, in
accordance with the Takedown Request.

                  (b)      Each Stockholder will notify the Company of each sale
                           under  Registration  Statement in accordance with the
                           Takedown  Request  within  24  hours  of the  sale by
                           faxing the  "Notification of Sale" attached hereto as
                           Exhibit B to:

                                 Carl F. Barnes
                       Vice President and General Counsel
                        PAREXEL International Corporation
                                 195 West Street
                          Waltham, Massachusetts 02451
                          Phone: (781) 487-9904 x 4158
                            Facsimile: (781) 890-4813

Based on the information set forth on the Notification of Sale, the Company will
prepare or cause to be prepared the  appropriate  notifications  to its Transfer
Agent to remove the legend described in Section 3 from the Shares so sold.

         14.      Miscellaneous.

                  (a)      All  covenants  and  agreements   contained  in  this
                           Agreement  by or on  behalf  of any  of  the  parties
                           hereto  shall  bind and inure to the  benefit  of the
                           respective  successors  and  assigns  of the  parties
                           hereto (including without  limitation  transferees of
                           any Shares,  provided that such transferee executes a
                           counterpart   signature  page  to  this   Agreement),
                           whether so expressed or not.

                  (b)      All  notices  and other  communications  which by any
                           provision of this Agreement are required or permitted
                           to be given  shall be given in  writing  and shall be
                           (i) mailed by  first-class  or express mail,  postage
                           prepaid, (ii) sent by telex,  telegram,  telescope or
                           other  form  of  rapid  transmission,   confirmed  by
                           mailing  (by first  class or  express  mail,  postage
                           prepaid) written  confirmation at  substantially  the
                           same  time  as  such  rapid  transmission,  or  (iii)
                           personally delivered to the receiving party (which if
                           other than an individual shall be an officer or other
                           responsible party of the receiving  party).  All such
                           notices and communications  shall be mailed,  sent or
                           delivered as follows:

         if to the Company, to:

         PAREXEL   International    Corporation
         195   West   Street   Waltham,
         Massachusetts  02451 
         Attn:  William T. Sobo, Jr., Senior Vice President and Chief Financial
         Officer 
         Facsimile: (781) 487-9931


         with a copy to:

                  Carl F. Barnes
                  Vice President and General Counsel
                  PAREXEL International Corporation
                  195 West Street
                  Waltham, Massachusetts  02451
                  United States of America
                  Facsimile: (781) 890-4813

         if to the  Stockholders,  to their addresses as set forth on Schedule A
         hereto;

         with a copy to:

                  Maitre Denis Polack
                  Amperal
                  155 Boulevard Haussmann
                  75008 Paris
                  FRANCE
                  Facsimile: 33-1-45-61-58-39

if to any  subsequent  holder of Shares,  to it at such address as may have been
furnished  to the Company in writing by such  Stockholder;  or, in any case,  at
such other  address or addresses as shall have been  furnished in writing to the
Company (in the case of a Stockholder)  or to the  Stockholders  (in the case of
the Company)in  accordance with the provisions of this paragraph.  Notices shall
be deemed  duly  delivered  five  business  days after being sent by first class
mail,  postage  prepaid,  or two business  days after being sent via a reputable
nationwide express mail service.  Notices delivered via any other means shall be
deemed duly delivered upon actual receipt by the individual for whom such notice
is  intended.   Any  notice  delivered  to  a  party  hereunder  shall  be  sent
simultaneously, by the same means, to such party's counsel as set forth above.

                  (c)      This Agreement  shall be governed by and construed in
                           accordance  with  the  laws  of the  Commonwealth  of
                           Massachusetts.

                  (d)      This  Agreement  may  be  amended  or  modified,  and
                           provisions  hereof  may be waived,  with the  written
                           consent of the Company and of  Stockholders  who hold
                           (from  time  to  time)  at  least a  majority  of the
                           outstanding Shares.

                  (e)      This  Agreement  may  be  executed  in  two  or  more
                           counterparts,  each  of  which  shall  be  deemed  an
                           original,  but all of which together shall constitute
                           one and the same instrument.

                  (f)      If any provision of this  Agreement  shall be held to
                           be   illegal,   invalid   or   unenforceable,    such
                           illegality,   invalidity  or  unenforceability  shall
                           attach  only to such  provision  and shall not in any
                           manner   affect  or  render   illegal,   invalid   or
                           unenforceable  any other provision of this Agreement,
                           and this  Agreement  shall be  carried  out as if any
                           such illegal, invalid or unenforceable provision were
                           not contained herein.

                  (g)      This   Agreement   shall   become    effective   upon
                           Completion.


     IN WITNESS WHEREOF, the parties hereto have duly executed this Agreement as
     of the day and year first above written.

                                           THE COMPANY:

                                           PAREXEL INTERNATIONAL CORPORATION

                                           By:      /s/ Barry Raymond Philpott
                                           Name     Barry Raymond Philpott
                                           Title:   Chief Administrative Officer

                                           STOCKHOLDERS:

                                           /s/ Herve Laurent
                                               Herve Laurent


                                           COMIR
                                           By: /s/ Christian Haas
                                           Title:  Attorney


                                           /s/ Philippe Conquet
                                               Philippe Conquet


                                           FINANVAL
                                           By: /s/ Philippe Conquet
                                           Title: Attorney




           [Each Stockholder must complete page 12 of this Agreement]


                             New Owner Questionnaire

          [Each Stockholder must complete this page of this Agreement]


Stockholder Name: ______________________________

Principal Residence Address:
Note: Non-principal residence addresses and post office boxes cannot be accepted

_______________________________________________
(Number and Street)

_______________________________________________
(City, State/Province) (Country)

_______________________________________________
(Residence Telephone)


Mailing Address (if different from above):

_______________________________________________
(Number and Street)

_______________________________________________
(City, State/Province) (Country)



Citizenship:_____________________________________


Social Security or Taxpayer I.D. No. (U.S. Persons only):_________________


<TABLE>


                                              Schedule A to Registration Rights Agreement

<CAPTION>
- -------------------------------------- -------------------------------------- ---------------------- -----------------------
                                                                                     Phone                    Fax
          Stockholder Name                            Address                        Number                  Number

- -------------------------------------- -------------------------------------- ---------------------- -----------------------
<S>                                   <C>                                    <C>                    <C>
Dr. Herve Laurent                      5, Avenue Rodin                        33/1 40 72 52 22       33/1 40 72 52 21
                                       75016 Paris, FRANCE

- -------------------------------------- -------------------------------------- ---------------------- -----------------------
Comir                                  27, Avenue Etienne Audibert BP 100
                                       60304 Senlis, FRANCE

- -------------------------------------- -------------------------------------- ---------------------- -----------------------
- -------------------------------------- -------------------------------------- ---------------------- -----------------------
Philippe Conquet                       12, rue de Madrid                      33/1 45 22 78 34
                                       75008 Paris, FRANCE

- -------------------------------------- -------------------------------------- ---------------------- -----------------------
- -------------------------------------- -------------------------------------- ---------------------- -----------------------
Finanval                               38, rue Bassano
                                       75008 Paris, FRANCE
- -------------------------------------- -------------------------------------- ---------------------- -----------------------

 


</TABLE>
<TABLE>
                   Exhibit A to Registration Rights Agreement

                                TAKEDOWN REQUEST

         The undersigned Stockholder intends to offer and sell to the public Shares of PAREXEL International Corporation registered
under a certain Registration Statement on Form S-3, File No. 333- _______.

<CAPTION>
- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------
 <S>                     <C>                            <C>                    <C>                   <C> 
                             Name, Address,
                          Telephone Number and                                  Number
     Name, Address,        Facsimile Number of                                    Of
  Telephone Number and    Agent, Broker-Dealer           Number                 Shares                Proposed
  Facsimile Number of        or Underwriter                Of                     To                    Date
      Stockholder                                        Shares                   Be                     Of
                                                         Owned                   Sold                   Sale*
- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------

- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------

- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------
</TABLE>
*        MUST BE AT LEAST FIVE AND NOT MORE THAN 15 BUSINESS DAYS AFTER THE DATE
         HEREOF.

Other Information:



                  The undersigned  Stockholder  agrees to provide all reasonably
         necessary  information and reasonably  necessary  materials and to take
         all  reasonably  necessary  actions  as may be  required  in order  for
         PAREXEL  International   Corporation  to  comply  with  all  applicable
         securities laws.


                                         _______________________________________
                                          Signature of Stockholder

                                         _______________________________________
                                          Print Name

                                         _______________________________________
                                          Date


           ALL TAKEDOWN REQUESTS SHOULD BE FORWARDED BY FACSIMILE TO:

                                 CARL F. BARNES
                       VICE PRESIDENT AND GENERAL COUNSEL
                        PAREXEL INTERNATIONAL CORPORATION
                                 195 WEST STREET
                          WALTHAM, MASSACHUSETTS 02451
                            UNITED STATES OF AMERICA
                          PHONE: (781) 487-9904 X 4158
                            FACSIMILE: (781) 890-4813

    AT LEAST FIVE AND NOT MORE THAN 15 BUSINESS DAYS PRIOR TO A PROPOSED SALE
<TABLE>
                                             Exhibit B to Registration Rights Agreement

                                                         NOTIFICATION OF SALE

The undersigned Stockholder sold to the public Shares of PAREXEL International Corporation registered under a certain Registration
Statement on Form S-3, File No. 333-_______, as follows.
<CAPTION>
- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------
 <S>                     <C>                            <C>                     <C>                   <C>             
                             Name, Address,
                          Telephone Number and
     Name, Address,        Facsimile Number of                                                         Number
  Telephone Number and    Agent, Broker-Dealer                                                           Of
  Facsimile Number of        or Underwriter              Number                                        Shares
      Stockholder                                          Of                    Date                   Owned
                                                         Shares                   Of                    After
                                                          Sold                   Sale                   Sale
- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------

- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------

- ------------------------- ---------------------- ----------------------- ---------------------- ----------------------

</TABLE>
Other Information:



                                         _______________________________________
                                         Signature of Stockholder

                                         _______________________________________
                                         Print Name

                                         _______________________________________
                                         Date



         ALL NOTIFICATIONS OF SALE SHOULD BE FORWARDED BY FACSIMILE TO:

                                 CARL F. BARNES
                       VICE PRESIDENT AND GENERAL COUNSEL
                        PAREXEL INTERNATIONAL CORPORATION
                                 195 WEST STREET
                          WALTHAM, MASSACHUSETTS 02451
                            UNITED STATES OF AMERICA
                          PHONE: (781) 487-9904 X 4158
                            FACSIMILE: (781) 890-4813

                        WITHIN 24 HOURS FOLLOWING A SALE



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