EPITOPE INC/OR/
8-K, 1997-06-04
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                -----------------

                                    FORM 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):

                                  June 3, 1997

                                -----------------


                                  EPITOPE, INC.
               (Exact name of Registrant as specified in charter)

                                     Oregon
                 (State or other jurisdiction of incorporation)

                                     1-10492
                              (Commission File No.)

                                   93-0779127
                        (IRS Employer Identification No.)

         8505 S.W. Creekside Place
             Beaverton, Oregon                             97008
 (Address of principal executive offices)                (Zip Code)

               Registrant's telephone number, including area code:

                                 (503) 641-6115




<PAGE>




Item 5.           Other Events.

                  On  June 3,  1997,  Epitope,  Inc.,  issued  a  press  release
regarding a change in management.  A copy of the press release is attached as an
exhibit to this report.

Item 7.           Financial Statements, Pro Forma Financial Information and
Exhibits.

                  (a)      Not applicable.

                  (b)      Not applicable.

                  (c)      Exhibits.

                  The  exhibits to this  report are listed in the exhibit  index
following the signature page.




<PAGE>



                                   SIGNATURES

                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  Registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                  EPITOPE, INC.


Dated:  June 4, 1997              By /s/ Gilbert N. Miller
                                     Gilbert N. Miller
                                     Executive Vice President and Chief
                                     Financial Officer



<PAGE>



                                  EXHIBIT INDEX


99       Press release of Epitope, Inc., dated June 3, 1997.




                                   Exhibit 99

FOR IMMEDIATE RELEASE                               Contact:       Gus Allen
                                                                   Mary Hagen
                                                                   503.641.6115

                       EPITOPE ANNOUNCES MANAGEMENT CHANGE

Beaverton,  Oregon, June 3, 1997 -- Epitope, Inc.  (NASDAQ:EPTO) today announced
that Adolph J. Ferro,  Ph.D., will devote full time to his position as president
and  chief  executive  officer  of  the  company's  Agritope  group,   effective
immediately.  W. Charles  Armstrong,  a member of the board of  directors,  will
serve as interim president and chief executive officer of Epitope, Inc.

"Management  and the board  have been  discussing  strategies  for  accelerating
Agritope's  development as a stand-alone  enterprise," Dr. Ferro stated. "I look
forward to turning my full attention to guiding  Agritope in its transition from
development-stage company to mature business."

Dr. Ferro was a co-founder of  Agricultural  Genetic  Systems,  Inc.,  which the
company  acquired in 1987 and renamed  Agritope,  Inc.  He is a  co-inventor  of
Agritope's  patented   ethylene-control   technology.   Agritope  is  developing
applications of the technology to control ripening in fruits and vegetables.

Roger Pringle,  chairman of the board, praised Dr. Ferro's accomplishments.  "Al
has done an  outstanding  job of  keeping  Epitope  fully  funded in the face of
regulatory  delays and other  hurdles that  prevented it from relying on product
revenues.  Now that our medical products are generating meaningful sales, we are
pleased that Al will devote his efforts to  commercializing  Agritope's  genetic
technology, which he was instrumental in developing."

The company will  immediately  initiate a search for a new  president  and chief
executive officer of Epitope, Inc. Mr. Armstrong,  who will succeed Dr. Ferro in
that capacity on an interim basis, has been a director of Epitope since 1989. He
is the former chief executive officer of Bank of America Oregon.

Mr. Pringle stated that the  management  change is part of a long-range  plan to
allow the  company's  Epitope  Medical  Products and Agritope  groups to operate
independently. The company's board of directors continues to consider a proposal
to  issue a  second,  separate  class of  common  stock  that  would  track  the
performance  of  Agritope.  The board also plans to consider  alternatives  that
could involve a spin-off or other divestiture of Agritope.

Epitope,  Inc. is a  biotechnology  company that  develops  and markets  medical
diagnostic  products  through its Epitope Medical  Products group.  Its Agritope
group is focused on the development and  commercialization of novel agricultural
products using plant genetic engineering and other modern methods.

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