EPITOPE INC/OR/
DEFA14A, 1997-05-28
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                           SCHEDULE 14A INFORMATION
Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
(Amendment No.  )

Filed by the Registrant [x]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[ ] Preliminary Proxy Statement          [ ] Confidential, for Use of 
[ ] Definitive Proxy Statement                 the Commission Only (as
[x] Definitive Additional Materials            permitted by 
[ ] Soliciting Material Pursuant to            Rule 14a-6(e)(2))
            Section 240.14a-11(c) 
            or Section 240.14a-12

                                  Epitope, Inc.
- --------------------------------------------------------------------------------

                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------

    (Name of  Person(s)  Filing Proxy  Statement  if other than the  Registrant)
Payment of Filing Fee (Check the appropriate box):
[x] No fee required.
[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

    1)  Title of each class of securities to which transaction applies:

- --------------------------------------------------------------------------------
    2)  Aggregate number of securities to which transaction applies:

- --------------------------------------------------------------------------------
    3)  Per unit  price  or  other  underlying  value  of  transaction  computed
    pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing
    fee is calculated and state how it was determined):

- --------------------------------------------------------------------------------
    4)  Proposed maximum aggregate value of transaction:
    
- --------------------------------------------------------------------------------
    5)  Total fee paid:
    
- --------------------------------------------------------------------------------

[ ] Fee paid previously with preliminary materials.

[ ] Check box if any part of the fee is offset as provided by Exchange  Act Rule
0-11(a)(2)  and  identify  the  filing  for  which the  offsetting  fee was paid
previously.  Identify the previous filing by registration  statement  number, or
the Form or Schedule and the date of its filing.

<PAGE>

    1)  Amount Previously Paid:
    
- --------------------------------------------------------------------------------
    2)  Form, Schedule or Registration Statement No.:
    
- --------------------------------------------------------------------------------
    3)  Filing Party:
    
- --------------------------------------------------------------------------------
    4)  Date Filed:
    
- --------------------------------------------------------------------------------


<PAGE>
[LOGO]
                                  Epitope, Inc.
                             8505 SW Creekside Place
                             Beaverton, Oregon 97008

                                 (503) 641-6115
                               Fax (503) 643-2781



                                  May 27, 1997


Dear Shareholder:

As you know, the 1997 annual meeting of shareholders  of Epitope,  Inc. has been
adjourned from its originally  scheduled date. The meeting will be reconvened on
Tuesday,  June 17, 1997, at 9:00 a.m., at the Greenwood  Inn,  10700 S.W.  Allen
Blvd., Beaverton, Oregon. Holders of Epitope Common Stock of record at the close
of business on March 7, 1997, are entitled to vote at the reconvened meeting. We
hope that you will be able to attend.

A new proxy card is included with this letter,  as explained  below. You may use
the new card to vote on the items to be considered at the reconvened meeting. IF
YOU PREVIOUSLY DATED,  SIGNED, AND RETURNED THE PROXY CARD SENT TO YOU IN MARCH,
YOU DO NOT NEED TO SEND US THE  ENCLOSED  CARD  UNLESS  YOU WANT TO CHANGE  YOUR
VOTING INSTRUCTIONS.

Reasons for Adjournment
- -----------------------

We are in the process of rescinding  our  acquisition  of Andrew and  Williamson
Sales,  Co.  (A&W).  We have also decided to withdraw,  for the time being,  the
proposal to create a new class of common stock called Agritope Stock.  The board
of directors  adjourned the annual  meeting to June 17 so that we could send you
additional information about these developments.

A&W Rescission.  As you know, we acquired A&W in December 1996. After A&W frozen
strawberries  grown in Mexico were alleged to be associated  with an outbreak of
Hepatitis A in Michigan,  we learned that Fred L.  Williamson,  president  and a
former  owner  of  A&W,  had  certified  the  strawberries  as U.S.  grown.  The
certification  occurred  before we acquired A&W. Mr.  Williamson is no longer an
executive officer of Epitope.

We recently  entered into an agreement with A&W and the former owners to rescind
the  acquisition.  The former owners have agreed to return the 520,000 shares of
Epitope Common Stock we used to acquire A&W, in exchange for the outstanding A&W
common stock. Under the agreement,  we will also receive A&W nonvoting preferred
stock with a liquidation  preference of $5.7 million, in return for cancellation
of loans made to A&W.

One of the former owners of A&W died on April 11, 1997.  The other former owners
have agreed to personally guarantee the $6.5 million credit facility provided by
A&W's bank in connection  with the  rescission  agreement.  The facility is also
secured by A&W accounts

<PAGE>



                                      - 2 -                         May 27, 1997


receivable  and inventory.  Our guarantee of the facility will continue  through
November 1, 1998.  The former  owners  guaranteeing  the facility have agreed to
reimburse us for any amounts we are required to pay under our guarantee. Closing
of the recission transaction is expected to occur shortly.

Withdrawal of Item 2, the Agritope  Stock  Proposal.  The  rescission of the A&W
acquisition  will  substantially  change  the  composition  of our  agricultural
biotechnology  group,  Agritope.  Consequently,  we have decided to withdraw the
Agritope Stock  proposal,  which appeared as item 2 in the 1997 Notice of Annual
Meeting  and  Prospectus/Proxy  Statement  we sent you in March (the March Proxy
Materials).  Accordingly,  the proposal will not be acted upon at the reconvened
meeting.  The board of directors  intends to study the Agritope  Stock  proposal
further  and may  submit  a  revised  proposal  to you for  approval  at a later
meeting.

Items to be Voted On
- --------------------

The remaining items that will be submitted for a vote at the reconvened  meeting
are item 1, the  election of three Class I directors,  item 3,  amendment of the
Epitope,  Inc. 1991 Stock Award Plan (the Award Plan),  and item 4, amendment of
the Epitope, Inc. 1993 Employee Stock Purchase Plan (the Purchase Plan).

Item 1. With  respect to item 1,  complete  information  about the  nominees for
director appears in the March Proxy Materials. If you would like another copy of
the March Proxy  Materials,  contact us as  described  below  under  "Additional
Information."

Items 3 and 4. Items 3 and 4, the proposals to amend the Award Plan and Purchase
Plan, are also described in the March Proxy Materials.  The proposed  amendments
to each plan include provisions  relating to Agritope Stock, which were intended
to  dovetail  with the  Agritope  Stock  proposal.  Among  other  things,  these
provisions  authorize  grants  of new  awards  under  the  Award  Plan for up to
1,000,000  shares of Agritope  Stock and the issuance of up to 250,000 shares of
Agritope Stock  pursuant to new  subscriptions  under the Purchase  Plan.  Until
shareholders  approve a revised  proposal  authorizing  the creation of Agritope
Stock as a class of common stock of Epitope,  these provisions in the Award Plan
and the Purchase  Plan will not take effect,  even if items 3 and 4 are approved
at the reconvened meeting.

Item 3: Award Plan Amendments.  Other  provisions of the proposed  amendments to
the Award Plan do not depend on approval of the Agritope Stock proposal and will
take effect if Item 3 is approved at the reconvened  meeting.  These  provisions
include:

         1. An  increase  in the  number  of  shares  of  Epitope  Common  Stock
authorized for issuance under the Award Plan by 1,000,000 shares;

         2. The  addition  of a  limitation  on the number of shares  subject to
options that may be granted under the Award Plan to a single individual during a
given fiscal year to 500,000 shares; and

<PAGE>


                                      - 3 -                         May 27, 1997



         3. The  deletion  of Article 14 of the Award Plan  regarding  awards to
nonemployee  directors,  which will have the effect of authorizing  the board of
directors to grant awards to  nonemployee  directors  pursuant to the Award Plan
from  time  to time in its  discretion  and in  accordance  with  its  fiduciary
obligations to Epitope and its shareholders.

If the Agritope Stock proposal had been adopted, Epitope Common Stock would have
been renamed Epitope Medical  Products Common Stock.  Accordingly,  the proposed
amendments to the Award Plan refer to Epitope Medical  Products Common Stock. If
the  amendments  are approved,  references in the Award Plan to Epitope  Medical
Products  Common Stock will be treated as references to Epitope  Common Stock so
long as Epitope has only one class of common stock outstanding.

As a result of the withdrawal of the Agritope Stock proposal,  the options shown
in the New Plan Benefits table on page 58 of the March Proxy  Materials will not
be  granted.  No  decisions  have been made  concerning  awards  relating to the
additional  1,000,000  shares of Epitope Common Stock that will become available
for grant upon approval of the proposed amendments to the Award Plan.

Item 4: Purchase Plan  Amendment.  If amendment of the Purchase Plan is approved
at the reconvened meeting,  the number of shares of Epitope Common Stock subject
to the Purchase Plan will be increased by 250,000  shares.  The number of shares
presently  available  for new  subscriptions  under the Purchase Plan is 199,405
shares.

As with the Award Plan,  references to Epitope Medical  Products Common Stock in
the  Purchase  Plan as proposed to be amended will be treated as  references  to
Epitope  Common  Stock so long as  Epitope  continues  to have only one class of
common stock outstanding.

Additional Information
- ----------------------

The March Proxy Materials included detailed  information  regarding Epitope, its
directors  and executive  officers,  executive  compensation  for the past three
fiscal years,  and the Award Plan and Purchase  Plan; a description of Epitope's
business;  an analysis of its results of operations and financial  condition for
the past three fiscal years;  and its audited  financial  statements and related
notes for the years ended September 30, 1996,  1995 and 1994 (including  audited
balance sheets at September 30, 1996 and 1995); as well as extensive information
concerning the Agritope Stock proposal and A&W. Additional information regarding
items 1, 3, and 4 appears on pages 29-32, 55-60, and 61-63, respectively, of the
March Proxy Materials.

If you would like to receive another copy of the March Proxy  Materials,  please
call Mary W. Hagen at (503) 641-6115, or write the Investor Relations Department
at Epitope, Inc., 8505 S.W. Creekside Place, Beaverton, Oregon 97008.

On May 22, 1997,  the closing  price of Epitope  Common Stock as reported on the
National Market tier of The Nasdaq Stock Market was $9.6875.


<PAGE>


                                      - 4 -                         May 27, 1997



Board Recommendations
- ---------------------

The board of directors recommends that you vote:

         1. FOR ITEM 1,  which  will  result in the  re-election  of W.  Charles
Armstrong, Adolph J. Ferro, Ph.D., and Roger L. Pringle as Class I directors for
a term of office expiring at the annual meeting in the year 2000;

         2. FOR ITEM 3, which, among other matters,  will increase the number of
shares of Epitope  Common Stock  available for issuance  under the Award Plan by
1,000,000 shares; and

         3. FOR ITEM 4, which, among other matters,  will increase the number of
shares of Epitope Common Stock available for issuance under the Purchase Plan by
250,000 shares.

Proxy Cards
- -----------

A proxy card and a pre-addressed, postage prepaid envelope are enclosed for your
use in voting at the reconvened  meeting.  IF YOU PREVIOUSLY DATED,  SIGNED, AND
RETURNED THE PROXY CARD SENT TO YOU WITH THE MARCH PROXY  MATERIALS,  YOU DO NOT
NEED TO DATE,  SIGN AND RETURN THE ENCLOSED PROXY CARD UNLESS YOU WISH TO CHANGE
YOUR VOTING INSTRUCTIONS.

Thank you for your continued interest and support.

Sincerely,


/s/ Adolph J. Ferro                                   /s/ Roger L. Pringle
Adolph J. Ferro, Ph.D.                                Roger L. Pringle
President and Chief Executive Officer                 Chairman




<PAGE>
PROXY

                                  EPITOPE, INC.
                       1997 ANNUAL MEETING OF SHAREHOLDERS
               PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS


The undersigned  hereby appoints Adolph J. Ferro,  Ph.D., and Gilbert N. Miller,
and each of them,  proxies with full power of  substitution,  to vote all of the
shares which the  undersigned  is entitled to vote at the 1997 Annual Meeting of
Shareholders of Epitope, Inc. (the "Company"),  which has been adjourned to June
17, 1997, and at any further adjournment or adjournments  thereof,  with all the
powers the undersigned would possess if personally present,  with respect to the
matters listed on the reverse side.

THE SHARES  REPRESENTED BY THIS PROXY,  IF PROPERLY  EXECUTED,  WILL BE VOTED AS
SPECIFIED ON THE REVERSE SIDE OR, IF NO SPECIFICATION IS MADE, WILL BE VOTED FOR
THE  ELECTION OF THE NOMINEES  LISTED ON THE REVERSE  SIDE AS DIRECTORS  AND FOR
ITEMS 3 AND 4. Item 2, the Agritope Stock Proposal,  has been withdrawn and will
not be acted upon at the meeting.  If any other  business  properly comes before
the meeting,  the proxies named above will have discretionary  authority to vote
thereon in accordance with their best judgment.

          PLEASE MARK, DATE, SIGN, AND RETURN THE PROXY CARD PROMPTLY.
                  (Continued and to be signed on reverse side.)



                              FOLD AND DETACH HERE






                                  EPITOPE, INC.


                       1997 ANNUAL MEETING OF SHAREHOLDERS

                                  ADJOURNED TO
                             TUESDAY, JUNE 17, 1997



<PAGE>



                         Please mark your votes as indicated in this example [X]

1.       Election of Class I Directors      FOR      WITHHOLD
         (Term Expiring 2000)               [ ]          [ ]
         W. Charles Armstrong
         Adolph J. Ferro, Ph.D.
         Roger L. Pringle
(Instruction: To withhold authority to vote for any individual nominee, mark FOR
and strike a line  through the  nominee's  name in the list  above.  To withhold
authority to vote for all nominees, mark WITHHOLD.)

2.       Agritope Stock Proposal -
         WITHDRAWN

3.       Approval of amendments
         to the Company's 1991
         Stock Award Plan.

         FOR      AGAINST     ABSTAIN
         [ ]        [ ]         [ ]

4.       Approval of amendments to the
         Company's 1993 Employee Stock
         Purchase Plan.

         FOR      AGAINST     ABSTAIN
         [ ]        [ ]         [ ]




Signature(s) --------------------------------------- Dated: --------------, 1997

         Please date and sign exactly as your name ppears on this Proxy.
If signing for estates, trusts, partnerships or corporations, title or capacity
     should be stated. If shares are held jointly, each holder should sign.







                              FOLD AND DETACH HERE






                                  EPITOPE, INC.



                       1997 ANNUAL MEETING OF SHAREHOLDERS

                                  ADJOURNED TO
                             TUESDAY, JUNE 17, 1997







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