EPITOPE INC/OR/
425, 2000-05-09
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                                       Filed  by  Epitope,  Inc.
                                                       pursuant   to  Rule   425
                                                       under the  Securities Act
                                                       of 1933, as amended

                                         Subject Company: STC Technologies, Inc.
                                         Epitope's Commission File No. 1-10492

[Logo] EPITOPE                           [Logo] STC Technologies Inc.




COMPANY CONTACTS:                           REPRESENTING EPITOPE:
Epitope, Inc.                               Lippert/Heilshorn & Associates
<TABLE>
<S>                                         <C>                          <C>                <C>
Charles E. Bergeron                         Bruce Voss                   310-575-4848       [email protected]
Chief Financial Officer                     Kim Sutton Golodetz          212-838-3777       [email protected]
503-641-6115                                Keith Lippert                212-838-3777       [email protected]
www.epitope.com                             MEDIA CONTACT:
                                            Pamela Rigler                212-838-3777       [email protected]
                                                                                            www.lhai.com
</TABLE>

                         STC Technologies, Inc.
Mike Gausling                      Rich Hooper
([email protected])            ([email protected])
Chief Executive Officer            Chief Financial Officer
610-882-1820                       610-882-1820
www.stctech.com



                      EPITOPE AND STC TECHNOLOGIES TO MERGE

               $200 MILLION ALL-STOCK DEAL CREATES ORAL FLUID AND
                    POINT-OF-CARE MEDICAL DIAGNOSTICS LEADER


BEAVERTON,  ORE. (MAY 8, 2000) - EPITOPE, INC. (NASDAQ NM: EPTO) today announced
that the Company has signed a definitive merger agreement with STC Technologies,
Inc., a privately-held company based in Bethlehem, Pennsylvania, under which the
two  companies  will  become  a  leader  in  the  fast-growing  oral  fluid  and
point-of-care medical diagnostics  industry.  The agreement has been approved by
the Board of  Directors  of each  company,  and is subject to typical  terms and
conditions,  including a vote of Epitope and STC  shareholders  expected to take
place in August  2000.  The  holders  of  approximately  52 percent of the STC's
shares have given irrevocable proxies to vote in favor of the merger.

STC  shareholders  will receive  Epitope  common stock in the merger.  The total
number of Epitope shares to be issued will be based on the average closing price
of Epitope common stock over a 20 trading-day  period prior to the completion of
the merger. At the current stock price, it is estimated that Epitope would issue
a total of 20 million shares to holders of STC's outstanding shares and options.

On a proforma  basis,  the new company  will have more than $20 million in cash,
trailing  12-month  revenues of $26.3 million,  a gross margin of 65%, and a net
loss of $4.1 million. Combining

                                     -more-
<PAGE>


operations  is  expected to result in at least $2 million in savings due to cost
synergies from the  consolidation  of duplicate  overhead and  consolidation  of
certain  manufacturing  operations.  For the 12 months ended March 31, 2000, STC
Technologies posted revenues of $14.8 million and a net loss of $1.0 million.

The  combined  company  will be  renamed  OraSure  Technologies,  Inc.,  will be
incorporated  under  Delaware  law,  and  will be  headquartered  in  Bethlehem,
Pennsylvania.  Robert D.  Thompson,  Epitope's  president  and  chief  executive
officer,  will be chief executive officer at the new company.  Michael Gausling,
STC's  president  and  chief  executive  officer,  will be  president  and chief
operating  officer.  The Epitope facility in Beaverton,  Oregon will continue to
focus on its current activities in the field of infectious disease.

Together,   Epitope  and  STC  will  leverage  their  expertise  in  oral  fluid
technology,  infectious disease testing and substance abuse testing.  The merger
combines the  developers  of the premier oral fluid  collection  device with the
leaders in oral fluid  assay  development.  Epitope's  OraQuick(R)  rapid  assay
platform and STC's Up-Converting Phosphor Technology (UPT(TM)),  which are under
development for a broad range of medical diagnostic applications, will provide a
substantial product pipeline for the combined company.

"Merging  these two great  companies  hits  dead-center on our shared mission to
become  the  world's  pre-eminent  oral  fluid  diagnostic  company,"  said  Mr.
Thompson.  "OraSure  Technologies  will have the  intellectual  capital  and the
technology  platforms  to  extend  the  reach of oral  fluid  testing,  touching
millions of lives. With our three platform technologies-  OraSure(R),  OraQuick,
and  UPlink(TM),  - we will be extremely  well  positioned  to  commercialize  a
variety of oral fluid testing  platforms for new and existing-use  applications.
The combination of laboratory  accuracy,  point-of-care  speed and  convenience,
non-invasive  anytime-anywhere  collection,  and competitive economics ensures a
prominent  place  for  rapid  oral  fluid  testing  in the  future  of  in-vitro
diagnostics. We intend to be the company that makes it happen."

"Over the past several  years,  Epitope and STC pioneered  oral fluid testing in
the  life  insurance  market.  Most  recently,  the  companies  collaborated  to
commercialize  Intercept(TM),  the first  laboratory  based  oral fluid test for
drugs of abuse, using the OraSure platform technology," said Mr. Gausling. "This
heritage gives us a great foundation for  commercializing  exciting new products
and technologies with a broad range of licensing opportunities."

OraQuick HIV is under development as the first product in the OraQuick line. The
product is a visually  read,  oral fluid  testing  device,  which can detect HIV
antibodies  within  20  minutes.  The  company  expects  to launch  the  product
internationally  in July 2000 and is preparing to enter  clinical  trials in the
United States.  The company plans to expand the OraQuick product line to include
tests for a variety of medical diagnostic applications.

UPT is a proprietary  label  detection  technology  being developed by STC. This
enabling  technology utilizes submicron phosphor particles that convert infrared
light to visible  light.  When used in conjunction  with  antibodies or DNA as a
probe  label,  UPT  assays  produce no  background  signal,  which  dramatically
increases  the  sensitivity  of the test  system.  In  addition  to  eliminating
background  signal,  these  particles allow  simultaneous  detection of multiple
biological  markers by the use of  different  UPT  particle  colors,  as well as
miniaturization  of the test platform and a permanent record of the test results
because of the stability of the UPT particles.  STC has demonstrated the utility
of UPT  labels in a lateral  flow  format  for use in a  variety  of  diagnostic
applications  under the  UPlinktrademark.  The first  UPlink  product  will be a
point-of-care  system  used to detect  drugs of abuse in oral  fluids,  which is
expected to be launched in the second half of 2001. STC has

                                     -more-
<PAGE>

collaborated with SRI International,  Menlo Park, CA, and Leiden University, the
Netherlands,  on the  development of the UPT  technology.  The Company has broad
patent protection for the use of UPT for biological applications.

The actual  number of shares to be issued in the merger is subject to adjustment
as follows: (i) issuance of 25 million shares if the average Epitope stock price
is between $6 and $8 per  share,  (ii)  issuance  of  Epitope  stock  worth $200
million  if the  average  Epitope  stock  price is between $8 and $10 per share,
(iii)  issuance  of 20 million  shares if the  average  Epitope  stock  price is
between $10 and $13 per share,  and (iv)  issuance  of Epitope  stock worth $260
million  if the  average  Epitope  stock  price is above  $13 per  share.  It is
anticipated  that  Epitope  shareholders  will own,  on a fully  diluted  basis,
approximately  50% of the  combined  company at the time the merger is affected,
subject to the average Epitope stock price prior to the merger.  The merger will
be tax  free  to the  stockholders  of  both  companies  and is  expected  to be
accounted for as a pooling of interests.

Deutsche Banc Alex. Brown advised Epitope in this  transaction,  while Robertson
Stephens advised STC  Technologies.  Robert Thompson,  Mike Gausling and Dr. Sam
Niedbala, chief science officer of STC, will be presenting at the DB Alex. Brown
healthcare conference on May 11, 2000.

The company will hold a conference call to discuss this  announcement  beginning
at 11:00 a.m. Eastern Time today.  Individual investors are invited to listen to
the conference  call over the Internet  through Vcall, a service of the Investor
Broadcast  Network,  at www.vcall.com.  To listen to the live call, please go to
the Web site at least 15  minutes  prior to the  start of the call to  register,
download and install any necessary  audio software.  In addition,  a replay will
begin shortly after the call has ended and will be available for 90 days.

STC Technologies,  Inc. develops,  manufactures and markets proprietary in vitro
diagnostic  products  and  medical  devices  for use in  clinical  laboratories,
physician  offices and workplace  testing.  STC is the leading  supplier of oral
fluid  assays  to  the  insurance  risk  assessment   testing  market  and  also
manufactures and markets other substance abuse testing products.  Epitope,  Inc.
develops,  manufactures  and markets  medical  devices and  diagnostic  products
utilizing  its  proprietary  oral fluid  technologies  for sale to  public-  and
private-sector  clients  worldwide.  The  Company's  primary  focus  is  on  the
detection of HIV antibodies, with emphasis in the U.S. life insurance and global
public health markets, and on the use of oral fluid testing for the detection of
drugs of abuse and other analytes.

This press release contains forward-looking statements.  Actual results could be
significantly  different.  Factors  that  could  affect  results  include  those
relating  to  the  proposed  merger,   including  failure  to  achieve  expected
synergies,  failure to obtain required regulatory or shareholder  approval,  and
unexpected  liabilities resulting from the two companies' operations prior to or
after the merger occurs. Other factors that could affect results include loss of
key personnel; failure to comply with regulations of the FDA or other regulatory
agencies;  obstacles to international  marketing of products; loss or impairment
of sources of capital; ability to develop product distribution channels; ability
to develop new products; development of competing products; market acceptance of
oral fluid testing products; and changes in international, federal or state laws
or regulations.  Although  forward-looking  statements help to provide  complete
information   about  future   prospects,   readers  should  keep  in  mind  that
forward-looking statements are much less reliable than historical information.

ADDITIONAL INFORMATION AND WHERE TO FIND IT:

EPITOPE  PLANS TO FILE A  REGISTRATION  STATEMENT ON SEC FORM S-4 IN  CONNECTION
WITH THE MERGER  AND TO MAIL A PROXY  STATEMENT/PROSPECTUS  TO  EPITOPE  AND STC
SHAREHOLDERS  CONTAINING  INFORMATION  ABOUT THE MERGER.  INVESTORS AND SECURITY
HOLDERS   ARE  URGED  TO  READ  THE   REGISTRATION   STATEMENT   AND  THE  PROXY
STATEMENT/PROSPECTUS   CAREFULLY  WHEN  THEY  ARE  AVAILABLE.  THE  REGISTRATION
STATEMENT AND THE PROXY  STATEMENT/PROSPECTUS WILL CONTAIN IMPORTANT INFORMATION
ABOUT  EPITOPE,  STC,  THE MERGER AND RELATED  MATTERS.  INVESTORS  AND SECURITY
HOLDERS  WILL BE ABLE TO OBTAIN FREE COPIES OF THESE  DOCUMENTS  THROUGH THE WEB
SITE   MAINTAINED   BY  THE  U.S.   SECURITIES   AND  EXCHANGE   COMMISSION   AT
HTTP//WWW.SEC.GOV.

                                     -more-
<PAGE>

EPITOPE FILES ANNUAL,  QUARTERLY AND SPECIAL REPORTS, PROXY STATEMENTS AND OTHER
INFORMATION WITH THE SECURITIES AND EXCHANGE  COMMISSION.  YOU MAY READ AND COPY
ANY REPORTS, STATEMENTS AND OTHER INFORMATION FILED BY EPITOPE AT THE SEC PUBLIC
REFERENCE  ROOMS  AT 450  FIFTH  ST.,  N.W.,  WASHINGTON,  D.C.  20549 OR AT THE
COMMISSION'S  OTHER PUBLIC REFERENCE ROOMS IN NEW YORK AND CHICAGO.  PLEASE CALL
THE  COMMISSION AT  800/SEC-0330  FOR FURTHER  INFORMATION  ON PUBLIC  REFERENCE
ROOMS. COPIES OF EPITOPE'S FILINGS WITH THE COMMISSION ALSO ARE AVAILABLE TO THE
PUBLIC FROM COMMERCIAL  DOCUMENT-RETRIEVAL SERVICES AND MAY BE OBTAINED FOR FREE
AT THE WEB SITE MAINTAINED BY THE COMMISSION AT HTTP//WWW.SEC.GOV, OR BY WRITING
EPITOPE AT: EPITOPE  INVESTOR  RELATIONS,  8505 SW CREEKSIDE  PLACE,  BEAVERTON,
OREGON 97008.

EPITOPE, ITS DIRECTORS, EXECUTIVE OFFICERS AND CERTAIN MEMBERS OF MANAGEMENT AND
EMPLOYEES MAY BE SOLICITING  PROXIES FROM EPITOPE  SHAREHOLDERS  IN FAVOR OF THE
APPROVAL OF THE MERGER  AGREEMENT.  A DESCRIPTION  OF ANY  INTERESTS,  DIRECT OR
INDIRECT,  THAT  EPITOPE'S  DIRECTORS AND EXECUTIVE  OFFICERS HAVE IN THE MERGER
WILL BE INCLUDED IN THE PROXY STATEMENT/PROSPECTUS.

                                      # # #


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