SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Schedule 13G
Under the Securities Exchange Act of 1934
(Amendment No. 1)*
INHALE THERAPEUTIC SYSTEMS, INC.
_______________________________________
(Name of Issuer)
Common Stock
_______________________________________
(Title of Class of Securities)
457191104
_______________________________________
(CUSIP Number)
Check the following box if a fee is being paid with this statement
____. (A fee is not required only if the filing person: (1) has a
previous statement on file reporting beneficial ownership of more
than five percent of the class of securities described in Item 1; and
(2) has filed no amendment subsequent thereto reporting beneficial
ownership of five percent or less of such class.) (See Rule 13d-7.)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject
class of securities, and for any subsequent amendment containing
information which would alter the disclosures provided in a prior
cover page.
The information required in the remainder of this cover page shall
not be deemed to be "filed" for the purpose of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject to the
liabilities of that section of the Act but shall be subject to all
other provisions of the Act (however, see the Notes).
(Continued on following page(s))
Page 1 of 6 Pages
<PAGE>
CUSIP NO. 457191104 13G Page 2 of 6 Pages
1 Name of Reporting Person
S.S. or I.R.S. Identification No. of Above Person
T. ROWE PRICE ASSOCIATES, INC.
52-0556948
2 Check the Appropriate Box if a Member of a Group*
(a) ____
NOT APPLICABLE (b) ____
3 SEC Use Only
______________________________
4 Citizenship or Place of Organization
MARYLAND
Number of 5 Sole Voting Power
**
Shares 530,423
Beneficially 6 Shared Voting Power
**
Owned By Each NONE
Reporting 7 Sole Dispositive Power
**
Person 1,819,123
With 8 Shared Dispositive Power
NONE
9 Aggregate Amount Beneficially Owned by Each Reporting Person
1,819,123
10 Check Box if the Aggregate Amount in Row (9) Excludes Certain
Shares*
NOT APPLICABLE
11 Percent of Class Represented by Amount in Row 9
11.5%
12 Type of Reporting Person*
IA
*SEE INSTRUCTION BEFORE FILLING OUT!
**Any shares reported in Items 5 and 6 are also
reported in Item 7.
CUSIP NO. 457191104 13G Page 3 of 6 Pages
1 Name of Reporting Person
S.S. or I.R.S. Identification No. of Above Person
T. ROWE PRICE NEW HORIZONS FUND, INC.
52-0791372
2 Check the Appropriate Box if a Member of a Group*
(a) ____
NOT APPLICABLE (b) ____
3 SEC Use Only
______________________________
4 Citizenship or Place of Organization
Maryland
Number of 5 Sole Voting Power
**
Shares 852,550
Beneficially 6 Shared Voting Power
**
Owned By Each NONE
Reporting 7 Sole Dispositive Power
**
Person NONE
With 8 Shared Dispositive Power
NONE
9 Aggregate Amount Beneficially Owned by Each Reporting Person
852,550
10 Check Box if the Aggregate Amount in Row (9) Excludes Certain
Shares*
NOT APPLICABLE
11 Percent of Class Represented by Amount in Row 9
5.4%
12 Type of Reporting Person*
IV
*SEE INSTRUCTION BEFORE FILLING OUT!
**The aggregate amount reported on this page is also included in the
aggregate amount reported by T. Rowe Price Associates, Inc. on page 2
of this Schedule 13G.
<PAGE>
SCHEDULE 13G
PAGE 4 OF 6
Item 1(a) Name of Issuer:
Reference is made to page 1 of this Schedule 13G
Item 1(b) Address of Issuer's Principal Executive Offices:
150 Industrial Road, San Carlos, California 94070
Item 2(a) Name of Person(s) Filing:
(1) T. Rowe Price Associates, Inc. ("Price Associates")
(2) T. Rowe Price New Horizons Fund, Inc.
X Attached as Exhibit A is a copy of an agreement between
the Persons Filing (as specified hereinabove) that this
Schedule 13G is being filed on behalf of each of them.
Item 2(b) Address of Principal Business Office:
100 E. Pratt Street, Baltimore, Maryland 21202
Item 2(c) Citizenship or Place of Organization:
(1) Maryland
(2) Maryland
Item 2(d) Title of Class of Securities:
Reference is made to page 1 of this Schedule 13G
Item 2(e) CUSIP Number: 457191104
Item 3 The person filing this Schedule 13G is an:
X Investment Adviser registered under Section 203 of the
Investment Advisers Act of 1940
X Investment Company registered under Section 8 of the
Investment Company Act of 1940
Item 4 Reference is made to Items 5-11 on page 2 of this Schedule
13G.
<PAGE>
SCHEDULE 13G
PAGE 5 OF 6
Item 5 Ownership of Five Percent or Less of a Class.
X Not Applicable.
_____ This statement is being filed to report the fact that, as of
the date of this report, the reporting person(s) has (have)
ceased to be the beneficial owner of more than five percent
of the class of securities.
Item 6 Ownership of More than Five Percent on Behalf of Another
Person
(1) Price Associates does not serve as custodian of the
assets of any of its clients; accordingly, in each
instance only the client or the client's custodian or
trustee bank has the right to receive dividends paid with
respect to, and proceeds from the sale of, such
securities.
The ultimate power to direct the receipt of dividends
paid with respect to, and the proceeds from the sale of,
such securities, is vested in the individual and
institutional clients which Price Associates serves as
investment adviser. Any and all discretionary authority
which has been delegated to Price Associates may be
revoked in whole or in part at any time.
Except as may be indicated if this is a joint filing with
one of the registered investment companies sponsored by
Price Associates which it also serves as investment
adviser ("T. Rowe Price Funds"), not more than 5% of the
class of such securities is owned by any one client
subject to the investment advice of Price Associates.
(2) With respect to securities owned by any one of the T.
Rowe Price Funds, only State Street Bank and Trust
Company, as custodian for each of such Funds, has the
right to receive dividends paid with respect to, and
proceeds from the sale of, such securities. No other
person is known to have such right, except that the
shareholders of each such Fund participate
proportionately in any dividends and distributions so
paid.
Item 7 Identification and Classification of the Subsidiary Which
Acquired the Security Being Reported on By the Parent Holding
Company.
Not Applicable.
Item 8 Identification and Classification of Members of the Group.
Not Applicable.
<PAGE>
SCHEDULE 13G
PAGE 6 OF 6
Item 9 Notice of Dissolution of Group.
Not Applicable.
Item 10 Certification.
By signing below I (we) certify that, to the best of my
(our) knowledge and belief, the securities referred to
above were acquired in the ordinary course of business and
were not acquired for the purpose of and do not have the
effect of changing or influencing the control of the issuer
of such securities and were not acquired in connection with
or as a participant in any transaction having such purpose
or effect. T. Rowe Price Associates, Inc. hereby declares
and affirms that the filing of Schedule 13G shall not be
construed as an admission that Price Associates is the
beneficial owner of the securities referred to, which
beneficial ownership is expressly denied.
Signature.
After reasonable inquiry and to the best of my (our)
knowledge and belief, I (we) certify that the information
set forth in this statement is true, complete and correct.
Dated: February 12, 1999 Dated: February 12, 1999
T. ROWE PRICE NEW HORIZONS T. ROWE PRICE ASSOCIATES, INC.
FUND, INC.
By: /s/ Carmen F. Deyesu By: /s/ Henry H. Hopkins
Carmen F. Deyesu, Henry H. Hopkins,
Treasurer Managing Director
Note: This Schedule 13G, including all exhibits, must be filed
with the Securities and Exchange Commission, and a copy
hereof must be sent to the issuer by registered or
certified mail not later than February 14th following the
calendar year covered by the statement or within the time
specified in Rule 13d-1(b)(2), if applicable.
12/31/1998
<PAGE>
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
T. Rowe Price Associates, Inc. (an investment adviser
registered under the Investment Advisers Act of 1940) and T. Rowe
Price New Horizons Fund, Inc., a Maryland corporation, hereby agree
to file jointly the statement on Schedule 13G to which this Agreement
is attached, and any amendments thereto which may be deemed
necessary, pursuant to Regulation 13D-G under the Securities Exchange
Act of 1934.
It is understood and agreed that each of the parties hereto is
responsible for the timely filing of such statement and any
amendments thereto, and for the completeness and accuracy of the
information concerning such party contained therein, but such party
is not responsible for the completeness or accuracy of information
concerning the other party unless such party knows or has reason to
believe that such information is inaccurate.
It is understood and agreed that a copy of this Agreement shall
be attached as an exhibit to the statement on Schedule 13G, and any
amendments hereto, filed on behalf of each of the parties hereto.
Dated: February 12, 1999 Dated: February 12, 1999
T. ROWE PRICE NEW HORIZONS T. ROWE PRICE ASSOCIATES, INC.
FUND, INC.
By: /s/ Carmen F. Deyesu By: /s/ Henry H. Hopkins
Carmen F. Deyesu, Henry H. Hopkins,
Treasurer Managing Director
