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OMB APPROVAL
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OMB Number: 3235-0145
Expires: August 31, 1999
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. )*
InSite Vision Incorporated
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(Name of Issuer)
Common Stock, Par Value $0.01 Per Share
- --------------------------------------------------------------------------------
(Title of Class of Securities)
457660 10 8
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(CUSIP Number)
February 16, 1999
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Date of Event Which Requires Filing of this Statement
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[ ] Rule 13d-1(b)
[X] Rule 13d-1(c)
[ ] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED
IN THIS FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY
VALID OMB CONTROL NUMBER.
<PAGE>
SCHEDULE 13G
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CUSIP NO. 457660 10 8 PAGE 2 OF 9 PAGES
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1. NAME OF REPORTING PERSONS
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
(ENTITIES ONLY)
Pharmacia & Upjohn AB
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
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4. CITIZENSHIP OR PLACE OF ORGANIZATION
Sweden
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5. SOLE VOTING POWER
NUMBER OF 1,095,506
SHARES --------------------------------------------------------------
BENEFICIALLY 6. SHARED VOTING POWER
OWNED BY -0-
EACH --------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON 1,095,506
WITH: --------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
-0-
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,095,506
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10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.0%
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12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
CO
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<PAGE>
SCHEDULE 13G
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CUSIP NO. 457660 10 8 PAGE 3 OF 9 PAGES
- -------------------------- -------------------------
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSONS
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
(ENTITIES ONLY)
Pharmacia & Upjohn Holdings B.V.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Netherlands
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5. SOLE VOTING POWER
NUMBER OF 1,095,506
SHARES --------------------------------------------------------------
BENEFICIALLY 6. SHARED VOTING POWER
OWNED BY -0-
EACH --------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON 1,095,506
WITH: --------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
-0-
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,095,506
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
OO
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<PAGE>
SCHEDULE 13G
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CUSIP NO. 457660 10 8 PAGE 4 OF 9 PAGES
- -------------------------- -------------------------
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSONS
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
(ENTITIES ONLY)
Pharmacia & Upjohn Inc.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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5. SOLE VOTING POWER
NUMBER OF 1,095,506
SHARES --------------------------------------------------------------
BENEFICIALLY 6. SHARED VOTING POWER
OWNED BY -0-
EACH --------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON 1,095,506
WITH: --------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
-0-
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,095,506
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
CO, HC
- --------------------------------------------------------------------------------
<PAGE>
CUSIP Number: 457660 10 8 Page 5 of 9
ITEM 1
(a). NAME OF ISSUER: InSite Vision Incorporated, a Delaware
corporation ("InSite").
(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 965
Atlantic Avenue, Alameda, California 94501.
ITEM 2.
(a). NAME OF PERSON FILING: Pharmacia & Upjohn AB, a Swedish
corporation ("P&U AB"), Pharmacia & Upjohn Holdings B.V., a "check the box"
entity incorporated in the Netherlands ("P&U BV") and Pharmacia & Upjohn, Inc.,
a Delaware corporation ("P&U Inc.", and together with P&U AB and P&U BV, the
"Reporting Persons").
(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE: The principal business
address of P&U AB is Pharmacia & Upjohn AB, S-171 97 Stockholm, Sweden. The
principal business address of P&U BV is Pharmacia & Upjohn Holdings B.V.,
Houttuinlaan 4, NL - 3447 GM Woerden, the Netherlands. The principal business
address of P&U Inc. is Pharmacia & Upjohn, Inc., 95 Corporate Drive,
Bridgewater, New Jersey 08807.
(c). CITIZENSHIP: P&U AB, is a Swedish corporation, P&U BV
is a "check the box" entity incorporated in the Netherlands and
P&U Inc. is a Delaware corporation.
(d). TITLE OF CLASS OF SECURITIES: Common stock, par value
$0.01 per share (the "Shares").
(e). CUSIP NUMBER: 457660 10 8
ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B) OR 13D-2(B) OR (C),
CHECK WHETHER THE PERSON FILING IS A:
(a). [ ] Broker or dealer registered under Section 15 of
the Exchange Act;
(b). [ ] Bank as defined in Section 3(a)(6) of the Exchange
Act;
<PAGE>
CUSIP Number: 457660 10 8 Page 6 of 9
(c). [ ] Insurance company as defined in Section 3(a)(19)
of the Exchange Act;
(d). [ ] Investment company registered under Section 8 of
the Investment Company Act;
(e). [ ] An investment advisor in accordance with Rule 13d-
1(b)(1)(ii)(E);
(f). [ ] An employee benefit plan or endowment fund in
accordance with Rule 13d-1(b)(1)(ii)(F);
(g). [ ] A parent holding company or control person in
accordance with Rule 13d-1(b)(1)(ii)(G);
(h). [ ] A savings association as defined in Section 3(b)
of the Federal Deposit Insurance Act;
(i). [ ] A church plan that is excluded from the definition
of an investment company under Section 3(c)(14) of
the Investment Company Act;
(j). [ ] Group in accordance with Rule 13d-1(b)(1)(ii)(j).
If this statement is filed pursuant to Rule 13d-1(c), check
this box. [x]
ITEM 4. OWNERSHIP.
(a). P&U AB beneficially owns 1,095,506 Shares of InSite.
P&U BV and P&U Inc. may be each deemed to beneficially own
1,095,506 Shares of InSite.
(b). The percentage interest held by each Reporting Person presented
below is based on the number of Shares that InSite represented to the
Reporting Persons to be issued and outstanding on February 16, 1999, as
adjusted to give effect to the issuance of the Shares to the Reporting
Persons by InSite (the "Outstanding Shares").
P&U AB beneficially owns approximately 6.0% of the Outstanding
Shares. P&U BV and P&U Inc. may be each deemed to beneficially own
approximately 6.0% of the Outstanding Shares.
<PAGE>
CUSIP Number: 457660 10 8 Page 7 of 9
(c). Each Reporting Person has the power to vote or direct the vote and
dispose or direct the disposition of the Shares beneficially owned by
such Reporting Persons as indicated in pages 2 through 4 above.
ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
If this statement is being filed to report the fact that as of the
date hereof the reporting person has ceased to be the beneficial owner
of more than five percent of the class of securities check the
following [ ].
ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF
ANOTHER PERSON.
Not Applicable.
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY
WHICH ACQUIRED THE SECURITY BEING REPORTED BY THE
PARENT HOLDING COMPANY.
See Exhibit 99.2.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF THE MEMBERS OF THE
GROUP.
Not Applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP.
Not Applicable.
<PAGE>
CUSIP Number: 457660 10 8 Page 8 of 9
ITEM 10. CERTIFICATION.
By signing below we certify that, to the best of our knowledge and
belief, the securities referred to above were not acquired and are not
held for the purpose of or with the effect of changing or influencing
the control of the issuer of the securities and were not acquired and
are not held in connection with or as a participant in any transaction
having that purpose or effect.
<PAGE>
CUSIP Number: 457660 10 8 Page 9 of 9
SIGNATURE
After reasonable inquiry and to the best of our knowledge and belief,
we certify that the information set forth in this statement is true, complete
and correct.
Dated: February 26, 1999
PHARMACIA & UPJOHN AB
By: /s/ Don W. Schmitz
---------------------------------
Title: Attorney-In-Fact
PHARMACIA & UPJOHN HOLDINGS B.V.
By: /s/ Don W. Schmitz
----------------------------------
Title: Attorney-In-Fact
PHARMACIA & UPJOHN, INC.
By: /s/ Don W. Schmitz
-----------------------------------
Title: Vice President and Secretary
<PAGE>
INDEX TO EXHIBITS
Exhibit No. Exhibit
- ----------- -------
99.1 Joint Filing Statement, dated February 26,
1999, between Pharmacia & Upjohn AB,
Pharmacia & Upjohn Holdings BV and Pharmacia
& Upjohn, Inc.
99.2 Item 7 Information
EXHIBIT 99.1
JOINT FILING STATEMENT
In accordance with Rule 13d-1(k)(1) promulgated under the Securities
Exchange Act of 1934, the undersigned agree to the joint filing of a Statement
on Schedule 13G (including any and all amendments thereto) with respect to the
Common Stock, $0.01 par value, of InSite Vision Incorporated, and further agree
to the filing of this agreement as an Exhibit thereto. In addition, each party
to this Agreement expressly authorizes each other party to this Agreement to
file on its behalf any and all amendments to such Statement on Schedule 13G.
Dated: February 26, 1999
PHARMACIA & UPJOHN AB
By: /s/ Don W. Schmitz
---------------------------------
Title: Attorney-In-Fact
PHARMACIA & UPJOHN HOLDINGS B.V.
By: /s/ Don W. Schmitz
----------------------------------
Title: Attorney-In-Fact
PHARMACIA & UPJOHN, INC.
By: /s/ Don W. Schmitz
-----------------------------------
Title: Vice President and Secretary
EXHIBIT 99.2
ITEM 7 INFORMATION
The securities being reported on by P&U Inc., as a parent holding company, are
all owned by P&U AB, a Swedish corporation, which is a wholly owned subsidiary
of P&U BV, a "check the box" entity incorporated in the Netherlands. P&U BV is a
wholly owned subsidiary of P&U Inc., a Delaware corporation.
