H&Q HEALTHCARE INVESTORS
13F-HR, 2000-11-07
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<PAGE>
                                                               -------------
                                    FORM 13F                   SEC USE ONLY
                                                               -------------

Page of        Name of Reporting Manager: HAMBRECHT & QUIST CAPITAL MANAGEMENT

<TABLE>
<CAPTION>
---------------------------------------------------------------------------------------------------------------------
                                                                                                     Item 5:
Item 1:                            Item 2:              Item 3:                 Item 4:              Shares of
Name of Issuer                     Title of Class       CUSIP                   Fair Market          Principal
                                                        Number                  Value                Amount
---------------------------------------------------------------------------------------------------------------------

<S>                                <C>                  <C>                     <C>                 <C>
Affymetrix                         Common               00826T108                4,987,500            100,000
---------------------------------------------------------------------------------------------------------------------
Amgen                              Common               031162100               10,474,219            150,000
---------------------------------------------------------------------------------------------------------------------
Aradigm                            Common               038505103                8,028,126            350,000
---------------------------------------------------------------------------------------------------------------------
ATS Medical                        Common               002083103                9,585,233            636,364
---------------------------------------------------------------------------------------------------------------------
Biofield                           Common               090591207                  878,766            878,766
---------------------------------------------------------------------------------------------------------------------
Biomatrix                          Common               09060P102                4,879,700            278,840
---------------------------------------------------------------------------------------------------------------------
Biopure                            Common               09065H915                3,066,038            169,746
---------------------------------------------------------------------------------------------------------------------
BioTransplant                      Common               09066Y107               12,157,339            712,519
---------------------------------------------------------------------------------------------------------------------
Biovail                            Common               09067K106               37,516,139            460,674
---------------------------------------------------------------------------------------------------------------------
Calypte Biomedical                 Common               131722100                2,495,671          1,093,993
---------------------------------------------------------------------------------------------------------------------
Catalytica                         Common               148885106               14,932,492          1,206,666
---------------------------------------------------------------------------------------------------------------------
Celgene                            Common               151020104               41,055,000            690,000
---------------------------------------------------------------------------------------------------------------------
Cor Therapeutics                   Common               217753102               18,693,751            300,000
---------------------------------------------------------------------------------------------------------------------
Corixa                             Common               21887F100                6,314,666            125,665
---------------------------------------------------------------------------------------------------------------------
Coulter Pharmaceutical             Common               222116105                7,651,875            265,000
---------------------------------------------------------------------------------------------------------------------
Cubist Pharmaceuticals             Common               229990981               49,876,142            958,005
---------------------------------------------------------------------------------------------------------------------
Curis                              Common               231269101               11,677,095            585,685
---------------------------------------------------------------------------------------------------------------------
CV Therapeutics                    Common               126667104               41,515,742            533,750
---------------------------------------------------------------------------------------------------------------------
Cytyc                              Common               232946103               23,492,861            544,762
---------------------------------------------------------------------------------------------------------------------
Digene                             Common               253752109                8,280,000            230,000
---------------------------------------------------------------------------------------------------------------------
Dyax (Restricted)                  Common               26746E103               17,939,360            546,765
---------------------------------------------------------------------------------------------------------------------
Elan                               Warrants             284131802                4,117,500             75,000
---------------------------------------------------------------------------------------------------------------------
Emisphere Technologies             Common               291345106                4,520,562            151,000
---------------------------------------------------------------------------------------------------------------------
Envirogen                          Common               294040100                   44,270             20,833
---------------------------------------------------------------------------------------------------------------------
EP MedSystems                      Common               26899B914                5,106,250          1,075,000
---------------------------------------------------------------------------------------------------------------------
Exelixis  (Restricted)             Common               30161Q104               45,005,625          1,687,500
---------------------------------------------------------------------------------------------------------------------
Focal                              Common               343909107                  696,941            271,977
---------------------------------------------------------------------------------------------------------------------
Gene Logic                         Common               368689105                5,175,000            225,000
---------------------------------------------------------------------------------------------------------------------
Genzyme                            Common               372917104               13,126,094            192,500
---------------------------------------------------------------------------------------------------------------------
Gilead Sciences                    Common               37555B103               39,121,034            356,659
---------------------------------------------------------------------------------------------------------------------
IDEXX Laboratories                 Common               45168D104                6,687,500            250,000
---------------------------------------------------------------------------------------------------------------------
ImClone Systems                    Common               45245W109               31,899,531            272,500
---------------------------------------------------------------------------------------------------------------------
Interpore Cross                    Common               46062W107                2,850,000            380,000
---------------------------------------------------------------------------------------------------------------------
KeraVision                         Common               648990992                  657,215            206,185
---------------------------------------------------------------------------------------------------------------------
Landec                             Common               514766104                2,928,612            526,492
---------------------------------------------------------------------------------------------------------------------
Lynx Therapeutics                  Common               551812308               11,742,188            375,000
---------------------------------------------------------------------------------------------------------------------
Martek Biosciences                 Common               572901106               15,214,369            780,224
---------------------------------------------------------------------------------------------------------------------
MedImmune                          Common               584699102               25,492,500            330,000
---------------------------------------------------------------------------------------------------------------------
Molecular Devices                  Common               60851C107               28,567,956            290,768
---------------------------------------------------------------------------------------------------------------------
Quintiles Transnational            Common               748767100                2,436,844            152,900
</TABLE>


<TABLE>
<CAPTION>

--------------------------------------------------------------------------------------------------------------------------------
                                              Item 6:                                                   Item 8:
                                       Investment Discretion                Item 7:              Voting Authority (Shares)
                                           (b) Shared-                      Managers
                                (a) Sole   As Defined    (c) Shared-       See Instr. V        (a) Sole   (b) Shared   (c) None
                                           in Instr. V       Other
---------------------------------------------------------------------------------------------------------------------------------
<S>                             <C>        <C>           <C>               <C>                 <C>        <C>          <C>
Affymetrix                           X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Amgen                                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Aradigm                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
ATS Medical                          X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Biofield                             X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Biomatrix                            X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Biopure                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
BioTransplant                        X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Biovail                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Calypte Biomedical                   X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Catalytica                           X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Celgene                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Cor Therapeutics                     X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Corixa                               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Coulter Pharmaceutical               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Cubist Pharmaceuticals               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Curis                                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
CV Therapeutics                      X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Cytyc                                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Digene                               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Dyax (Restricted)                    X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Elan                                 X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Emisphere Technologies               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Envirogen                            X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
EP MedSystems                        X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Exelixis  (Restricted)               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Focal                                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Gene Logic                           X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Genzyme                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Gilead Sciences                      X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
IDEXX Laboratories                   X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
ImClone Systems                      X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Interpore Cross                      X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
KeraVision                           X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Landec                               X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Lynx Therapeutics                    X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Martek Biosciences                   X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
MedImmune                            X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Molecular Devices                    X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Quintiles Transnational              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------

--------------------------------------------------------------------------------------------------------------------------------
</TABLE>



<PAGE>



<TABLE>
<CAPTION>

Page of        Name of Reporting Manager: HAMBRECHT & QUIST CAPITAL MANAGEMENT
---------------------------------------------------------------------------------------------------------------------
                                                                                                     Item 5:
Item 1:                                  Item 2:              Item 3:                 Item 4:              Shares of
Name of Issuer                           Title of Class       CUSIP                   Fair Market          Principal
                                                              Number                  Value                Amount
---------------------------------------------------------------------------------------------------------------------

<S>                                      <C>                  <C>                     <C>                 <C>
---------------------------------------------------------------------------------------------------------------------
Scios                                    Common               808905103                5,784,063            557,500
---------------------------------------------------------------------------------------------------------------------
Sepracor                                 Common               817315104               43,817,568            357,138
---------------------------------------------------------------------------------------------------------------------
Telik (Restricted)                       Common               87959M109                4,559,996            666,666
---------------------------------------------------------------------------------------------------------------------
Teva Pharmaceutical Industries           Common               881624209                7,318,750            100,000
---------------------------------------------------------------------------------------------------------------------
Transkaryotic Therapies                  Common               893735100                8,610,089            199,944
---------------------------------------------------------------------------------------------------------------------
Transkaryotic Therapies (Restricted)     Common               893735100                  830,452             24,106
---------------------------------------------------------------------------------------------------------------------
Tularik                                  Common               899165104               13,378,365            405,405
---------------------------------------------------------------------------------------------------------------------
Verdant Brands                           Common               923366108                    9,500             38,000
---------------------------------------------------------------------------------------------------------------------
Versicor (Restricted)                    Common               925314106               11,778,086          1,046,941
---------------------------------------------------------------------------------------------------------------------

---------------------------------------------------------------------------------------------------------------------
COLUMN TOTALS                                                                        676,974,575
---------------------------------------------------------------------------------------------------------------------

---------------------------------------------------------------------------------------------------------------------


--------------------------------------------------------------------------------------------------------------------------------
                                              Item 6:                                                   Item 8:
                                       Investment Discretion                Item 7:              Voting Authority (Shares)
                                           (b) Shared-                      Managers
                                (a) Sole   As Defined    (c) Shared-       See Instr. V        (a) Sole   (b) Shared   (c) None
                                           in Instr. V       Other
---------------------------------------------------------------------------------------------------------------------------------
<S>                             <C>        <C>           <C>               <C>                 <C>        <C>          <C>
Scios                                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Sepracor                             X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Telik (Restricted)                   X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Teva Pharmaceutical Industries       X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Transkaryotic Therapies              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Transkaryotic Therapies (Restricted) X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Tularik                              X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Verdant Brands                       X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------
Versicor (Restricted)                X                                         NA                   X
--------------------------------------------------------------------------------------------------------------------------------

--------------------------------------------------------------------------------------------------------------------------------
COLUMN TOTALS
--------------------------------------------------------------------------------------------------------------------------------

--------------------------------------------------------------------------------------------------------------------------------
</TABLE>


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