PSYCHEMEDICS CORP
10-K405, 2000-03-24
MEDICAL LABORATORIES
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<PAGE>   1
                    U. S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-K

         ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
                              EXCHANGE ACT OF 1934

                   FOR THE FISCAL YEAR ENDED DECEMBER 31, 1999

                         COMMISSION FILE NUMBER: 1-13738

                            PSYCHEMEDICS CORPORATION
             (exact name of registrant as specified in its charter)

           Delaware                                     58-1701987
- ---------------------------------           ------------------------------------
  (State or other jurisdiction              (I.R.S. Employer Identification No.)
of incorporation or organization)

1280 Massachusetts Ave., Cambridge, MA                    02138
- ---------------------------------------                 ----------
(Address of principal executive offices)                (Zip Code)

        Registrant's telephone number, including area code: 617-868-7455

           Securities registered pursuant to Section 12(b) of the Act:

Common Stock, $.005 Par Value                  American Stock Exchange
- -----------------------------        -------------------------------------------
     (Title of class)                (name of each exchange on which registered)

        Securities registered pursuant to Section 12(g) of the Act: None

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.
                                 YES (X) NO ( )
Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-B is not contained herein and will not be contained, to the best
of registrant's knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. (X)

On March 15, 2000 the aggregate market value of the voting stock held by
non-affiliates of the registrant (assuming for these purposes, but without
conceding, that all executive officers, directors and 10% shareholders are
"affiliates" of the Registrant) was $76,332,879 and 21,282,676 shares of Common
Stock, $.005 par value, were outstanding at such date.

                       DOCUMENTS INCORPORATED BY REFERENCE
                       -----------------------------------

Part III - Portions of the Registrant's Proxy Statement relative to the 2000
Annual Meeting of Stockholders to be held on May 11, 2000.


<PAGE>   2


                                     PART I
                                     ------

The information provided by the Company in this Report may contain
"forward-looking" information which involves risks and uncertainties, such as
statements of the Company's plans, objectives, expectations and intentions. The
cautionary statements made in this report should be read as being applicable to
all forward-looking statements wherever they appear in this report. The
Company's actual results could differ materially from those discussed herein.
Factors that could cause or contribute to such differences include those
discussed in Item 7 below, as well as those discussed elsewhere herein.

ITEM 1.   BUSINESS

GENERAL

Psychemedics Corporation ("the Company") is a Delaware corporation organized on
September 24, 1986 to provide testing services for the detection of abused
substances through the analysis of hair samples. The Company's testing methods
utilize a patented technology for performing immunoassays on enzymatically
dissolved hair samples with confirmation testing by mass spectrometry.

The Company's first application of its patented technology is a testing service
that screens for the presence of certain drugs of abuse in hair. The application
of radioimmunoassay procedures using hair differs from the more widely used
application of radioimmunoassay procedures using urine samples. The Company's
tests provide quantitative information which indicates the approximate amount of
drug ingested as well as historical data which can show a pattern of individual
drug use over a period of time. This information is useful to employers in both
applicant and employee testing, to physicians, treatment professionals, law
enforcement agencies, to the insurance industry; and to parents concerned about
drug use by their children and to other individuals and entities engaged in any
business where drug use is an issue. The Company provides commercial testing and
confirmation by mass spectrometry using industry accepted practices for cocaine,
marijuana, PCP, methamphetamine, and opiates. In addition, the Company has
developed a test for methadone for use in the drug treatment industry.

Testing services are currently performed at the Company's laboratory at 5832
Uplander Way, Culver City, California. The Company's services are marketed under
the name RIAH (Radioimmunoassay of Hair), a registered service mark.

DEVELOPMENT OF RADIOIMMUNOASSAY OF HAIR

The application of special radioimmunoassay procedures to the analysis of hair
was initially developed in 1978 by the founders of the Company, Annette
Baumgartner and Werner A. Baumgartner, Ph.D. The Baumgartners demonstrated that
when certain chemical substances enter the bloodstream, the blood carries them
to the hair where they become "entrapped" in the protein matrix in amounts
roughly proportional to the amount ingested. The Company's drugs of abuse
testing procedure involves washing the hair sample to clean it of surface
contaminants and then subjecting the cleaned hair sample to the Company's unique
proprietary process which involves the direct analysis of liquefied hair samples
by radioimmunoassay procedures utilizing special reagents and antibodies. The
antibodies detect the presence of a specific drug or metabolite in the liquefied
hair sample by reacting with the drug present in the sample solution and an
added radioactive analog of the drug. The resulting antibody-drug complex is
precipitated and analyzed. The amount of drug present in the sample is inversely
proportional to the amount of radioactive analog in the precipitate. Depending
upon both the length of hair and the hair growth rate (hair grows approximately
1.3 centimeters per month), the Company is able to provide historical
information on drug use by the person from whom the sample was obtained. Another
testing option involves


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<PAGE>   3


sectional analysis of the hair sample. In this procedure, the hair is sectioned
lengthwise to approximately correspond to certain time periods. The sections are
then labeled by time period, which allows the Company to provide trend
information on drug use.

VALIDATION OF THE COMPANY'S PROPRIETARY TESTING METHOD

The process of analyzing human hair for the presence of drugs using the
Company's patented method has been the subject of over sixty-five scientific
field studies. Results from the studies that have been published or accepted for
publication in scientific journals are generally favorable to the Company's
technology. These studies were performed with the following organizations:
Citizens for a Better Community Court, Columbia University, Koba Associates-DC
Initiative, Harvard Cocaine Recovery Project, Hutzel Hospital, ISA Associates
(Interscience America)-NIDA Workplace Study, University of California-Sleep
State Organization, Maternal/Child Substance Abuse Project, Matrix Center,
National Public Services Research Institute, Narcotic and Drug Research
Institute, San Diego State University-Chemical Dependency Center, Spectrum Inc.,
Stapleford Centre (London), Task Force on Violent Crime (Cleveland, Ohio);
University of Miami-Department of Psychiatry, University of Miami-Division of
Neonatology, University of South Florida-Operation Par Inc., University of
Washington, VA Medical Center-Georgia, U.S. Probation Parole-Santa Ana. The
above studies include research in the following areas: prenatal, treatment
evaluation, workplace drug use, the criminal justice system and epidemiology.
Many of the studies have been funded by the National Institute of Justice or the
National Institute on Drug Abuse ("NIDA"). Over 400 research articles written by
independent researchers have been published supporting the general validity and
usefulness of hair analysis.

An additional independent evaluation of the technology, favorable to the
Company's services, has been performed by submission of blind samples by Dr.
Robert DuPont, President of the Institute of Behavior and Health, Inc., the
first Director of the National Institute on Drug Abuse and presently Chairman of
the Company's Scientific Advisory Board. Some of the Company's customers have
also completed their own testing to validate the Company's proprietary hair
testing method as a prelude to utilizing the Company's services. These studies
have consistently confirmed the Company's superior detection rate. When the
results from utilizing the Company's patented hair testing method were compared
to urine results in side-by-side evaluations, 3 to 10 times as many drug abusers
were accurately identified with the Company's proprietary method. In addition to
these studies, the Company has over 1,700 clients for whom it performs testing.

In 1998, the National Institute of Justice, utilizing Psychemedics hair testing,
completed a Pennsylvania Prison study where hair analysis revealed an average
prison use level in 1996 of approximately 7.9%. Comparatively, urinalysis
revealed virtually no positives. After measures to curtail drug use were
instituted, drug sniffing dogs, searches and scanners, the use level fell to
approximately 2% according to the results of hair analysis in 1998. Again, the
urine tests had virtually no positives. The study illustrated the usefulness of
hair analysis to monitor populations and the weakness of urinalysis.

In July of 1999, the scientific validity of the Company's hair analysis for
workplace testing was reported in an article published in the Journal of
Occupational and Environmental Medicine by Benjamin Hoffman, M.D. The study
reported hair analysis and urinalysis results on a group of 1,852 candidates for
employment at a large metropolitan police department and presented the largest
analysis of pre-employment hair analysis to be published in the peer-reviewed
literature. The results demonstrated the superior capability of hair analysis
over urinalysis in detecting drug users by a three to one ratio and also showed
no evidence of a bias of hair analysis based on hair color or race.



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<PAGE>   4

ADVANTAGES OF USING THE COMPANY'S PATENTED METHOD

The Company asserts that hair testing using its patented method confers
substantive advantages relative to existing means of drug detection through
urinalysis. Although urinalysis testing can provide accurate drug use
information, the scope of the information is short-term and is generally limited
to the type of drug ingested within a few days of the test. Studies published in
many scientific publications have indicated that most drugs disappear from urine
within a few days.

In contrast to urinalysis testing, hair testing using the Company's patented
method provides long-term historical drug use information resulting in a
significantly wider "window of detection." This "window" may be three months or
longer depending on the length of the hair sample. The Company's standard test
offering, however, uses a 3.9 centimeter length cut close to the scalp;
therefore, it measures use for approximately the previous 90 days.

This wider window of detection enhances the detection efficiency of hair
analysis making it particularly useful in pre-employment testing. Hair testing
not only identifies more drug users, but can also uncover patterns and severity
of drug use, information most helpful in determining the scope of an
individual's involvement with drugs and serves as a deterrent against the use of
drugs. Hair testing using the Company's patented method greatly reduces the
incidence of "false negatives" associated with evasive measures typically
encountered with urinalysis testing. Urinalysis test results are impacted
adversely by excessive fluid intake prior to testing as well as adulteration of
the sample. Moreover, a drug user who abstains from use for a few days prior to
urinalysis testing can usually escape detection. Hair testing is effectively
free of these problems, as it cannot be thwarted by evasive measures typically
encountered with urinalysis testing. It is also attractive to customers since
sample collection is typically performed under close supervision yet is less
intrusive and less embarrassing for test subjects.

Hair testing using the Company's patented method (with mass spectrometry
confirmation) further reduces the prospects of error in conducting drug
detection tests. Urinalysis testing is more susceptible to problems such as
"evidentiary false positives" resulting from passive drug exposure (e.g. poppy
seeds). To combat this problem, in federally mandated testing the opiate cutoff
levels for urine testing were raised 667% on December 1, 1998 and testing for
the presence of a heroin metabolite, 6-AM, was required. These new results,
however, effectively reduced the detection time frame for confirmed heroin in
urine down to several hours post-use. In contrast, the metabolite 6-AM is stable
in hair and can be detected for months. In the event a positive urinalysis test
result is challenged, the only remedy is a newly collected sample. Depending on
the drug usage of the forewarned individual prior to the date of the newly
collected sample, a re-test may yield a negative result when using urinalysis
testing because of temporary abstention. In contrast, when the Company's hair
testing method is offered on a repeat hair sample the individual suspected of
drug use cannot as easily affect the results because historical drug use data
remain locked in the hair fiber.

DISADVANTAGES OF HAIR TESTING

There are some disadvantages of hair testing as compared to drug detection
through urinalysis. Because hair starts growing below the skin surface, drug
ingestion evidence does not appear in hair above the scalp until five to seven
days after use.

Thus, hair testing is not suitable for determining impairment in "for cause"
testing such as is done in connection with an accident investigation. It does,
however, provide a drug history which can complement urinalysis information in
"for cause" testing.

Currently, radioimmunoassay testing using hair samples under the Company's
patented method is only practiced by Psychemedics Corporation. The absence of
widespread familiarity and use of hair testing may adversely impact the
Company's revenue growth.


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The Company's prices for its tests are generally somewhat higher than prices for
tests using urinalysis, but the Company believes that its superior detection
rates provide more value to the customer. This pricing policy could, however,
adversely impact the growth of the Company's sales volume.

PATENTS

In December 1987, Dr. Werner A. Baumgartner, the Company's founder and Director
of Research and Development, with the assistance of the Company's patent
counsel, filed the first in a series of patent applications in the U.S. Patent
and Trademark Office on his inventions relating to radioimmunoassay using hair.
In 1994, U.S. Patent No. 5,324,642 (the "642 Patent") was issued to the Company.
This patent pertains to the universal drug extraction procedure and immunoassay
technology for the detection of drugs in hair specimens. In 1995, the Company
was granted an additional patent covering Dr. Baumgartner's inventions
pertaining to the immuno chemical screening assay for marijuana, which is the
most difficult drug to detect.

In August 1999, the Canadian Patent Office issued the Company a patent
containing broad claims to the Company's proprietary basic hair analysis method.

In December 1999, the Company was issued European patents related to the
analysis of marijuana analyte in hair. As a result of the issuance of this
patent, national patents are in effect in Germany, France, Italy, the United
Kingdom and Spain. This follows the issuance in Europe of the Company's first
European patent on the base hair analysis method in 1996, and the issuance in
Europe, also in 1996, of a patent on another aspect of the Company's technology,
related to the use of detergents to enhance the hair digestion portion of the
methodology.

In February 2000, a third U.S. patent was issued which extends protection to yet
another aspect of the Company's methodology. This patent provides for the use of
metal salt to deactivate certain reagents used in the method, thus enhancing
efficiency.

In October 1998, the Company was informed by the Japanese Patent Office that it
had allowed the pending Japanese patent application containing broad claims to
the Company's proprietary hair test for drugs of abuse. The Japanese patent,
combined with others in place in the United States and Europe, affords the
Company the opportunity to eventually expand drugs of abuse hair testing
technology throughout the world.

Pursuant to an agreement dated January 1987, Werner A. Baumgartner and Annette
Baumgartner granted to the Company an exclusive royalty-free worldwide license
of all of their rights in and to their inventions relating to radioimmunoassay
using hair.

Most of Dr. Baumgartner's research on the inventions covered by the 642 Patent
was conducted while he was employed by the Veteran's Administration Hospital
("VA"). Dr. Baumgartner has, therefore, also granted to the U.S. government, for
all governmental purposes, a nonexclusive, irrevocable, royalty-free license to
use the basic invention during the term of the patent with respect to such
invention.

Certain aspects of the Company's hair analysis method are based on trade secrets
owned by the Company. The Company's ability to protect the confidentiality of
these trade secrets is dependent upon the Company's internal safeguards and upon
the laws protecting trade secrets and unfair competition. In the event that
patent protection or protection under the laws of trade secrets were not
sufficient and the Company's competitors succeeded in duplicating the Company's
products, the Company's business could be materially adversely affected.



                                       5
<PAGE>   6

TARGET MARKETS

1. Industry

The Company focuses its primary marketing efforts on the private sector, with
particular emphasis on job applicant and employee testing.

The number of businesses using drug testing to screen job applicants and
employees has increased significantly in the last several years. The most recent
American Management Association (AMA) survey from 1996 indicated that 81% of
surveyed firms were engaged in some form of drug testing, a 277% increase since
the initial AMA survey in 1987. The prevalence of drug screening programs
reflects a growing concern that drug use contributes to employee health problems
and costs (increased absenteeism, reduced productivity, etc.) and in certain
industries, safety hazards. It has been estimated that the cost to industry in
terms of health care costs and lost productivity is at least $60 billion
annually.

The principal criticism of employee drug screening programs centers on the
effectiveness of the testing program. Most private sector screening programs use
urinalysis. Such programs are susceptible to evasive maneuvers and the inability
to obtain identical repeat samples in the event of a challenged result.

Moreover, many employers, to accommodate concerns of their employees and to
avoid infringement of employee privacy rights, conduct their programs on a
pre-announced schedule, thereby providing an opportunity for many drug users to
abstain in order to escape detection.

The Company presents its patented hair analysis method to potential clients as a
better technology well suited to employer needs. Field studies and actual client
results support the accuracy and effectiveness of the Company's patented
technology and its ability to detect even casual drug use. This information
provides an employer with greater flexibility in assessing the scope of an
applicant's or an employee's drug problem.

The Company performs a confirmation test of all positive results through mass
spectrometry. The use of mass spectrometry is an industry accepted practice used
to confirm positive drug test results of an initial screen. In an employment
setting, mass spectrometry confirmation is typically used prior to the taking of
any disciplinary action against an employee. The Company offers its clients a
five-drug screen with mass spectrometry confirmation of cocaine, PCP, marijuana,
methamphetamine, and opiates.

2. Home Use

The Company also offers a personal drug testing service, "PDT-90"(R), for
parents concerned about drug use by their children. It allows parents to collect
a small sample from their child in the privacy of the home and have it tested
for drugs of abuse by the Company. The PDT-90 testing service uses the same
patented method that is used with the Company's workplace testing service.

3. Research

The Company is currently conducting more than forty research investigations
worldwide, including studies of: drug abuse in juveniles and children with
Attention Deficit Disorders, the relationship of drug use and HIV infection,
pre-natal drug exposure and drug abuse among the homeless. Several nationwide
treatment evaluation and outcome studies are also using hair analysis results as
the primary measure of treatment efficacy. Hair analysis is also being applied
in numerous criminal justice studies, including use in pre-trial, probation,
parole, and prison testing and community needs assessment research. These
projects are being conducted at the nation's leading research institutions,
including Boston University, Columbia University Medical School, Duke
University, University of Pennsylvania, Massachusetts General Hospital, Harvard
University, Yale University and the University of Colorado Health Sciences
Center.


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<PAGE>   7


SALES AND MARKETING

The Company markets its corporate drug testing services primarily through its
own direct sales force. The Company markets PDT-90, its home testing drug
service, primarily through retail drug stores. For both its business-to-business
and consumer direct services, the Company has undertaken an integrated marketing
campaign to enhance the market presence within each respective segment. In 1998,
the Company began marketing its testing services over the Internet at several
websites.

COMPETITION

The Company competes directly with numerous commercial laboratories that test
for drugs through urinalysis testing. Most of these laboratories, such as
Laboratory Corporation of America, have substantially greater financial
resources, market identity, marketing organizations, facilities, and numbers of
personnel than the Company. The Company has been steadily increasing its base of
corporate customers and believes that future success with new customers is
dependent on the Company's ability to communicate the advantages of implementing
a drug program utilizing the Company's patented hair analysis method.

The Company's ability to compete is also a function of pricing. The Company's
prices for its tests are generally somewhat higher than prices for tests using
urinalysis. However, the Company believes that its superior detection rates,
coupled with the customer's ability to test less frequently due to hair
testing's wider window of detection (approximately 90 days versus approximately
three days with urinalysis) provide more value to the customer. This pricing
policy could, however, lead to slower sales growth for the Company.

The Company is not aware of any other laboratories with a hair analysis
technology that is comparable in effectiveness to the Company's proprietary
procedures. The Company is aware of several laboratories that purport to test
hair samples using a method, which the Company presumes, includes the use of a
form of immunoassay procedures. The Company, however, does not believe that
immunoassay testing of hair samples is effective on a commercial basis without
using the Company's unique patented method which allows for the efficient
release of drugs from the hair through enzyme digestion without destroying the
drugs.

GOVERNMENT REGULATION

The Company is licensed as a Clinical Laboratory by the State of California as
well as certain other states. All tests are performed according to the standards
established by the Clinical Laboratories Improvement Amendments ("CLIA") and
various state licensing statutes. Presently there are no other regulations
required for the operation of a clinical laboratory in the State of California.

A substantial number of states regulate drug testing. The scope and nature of
such regulation varies greatly from state to state and is subject to change from
time to time. The Company addresses state law issues on an ongoing basis.

In November 1999, the Oklahoma State Department of Health approved employment
drug testing using hair analysis and the Company was granted a license specific
to hair analysis. As of March 15, 2000, the Company was the only clinical
laboratory to have received such a license in Oklahoma.

Shortly after the introduction of the Company's PDT-90 drug testing service in
1995, the United States Food and Drug Administration ("FDA") attempted to assert
jurisdiction over the Company's PDT-90 service by claiming that the collection
envelope distributed as part of the service was a medical device. This
ultimately led to the Company filing suit


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against the FDA contesting the FDA's position. In March 1996, the FDA agreed to
withdraw its claims against the Company in exchange for the Company's agreement
to discontinue its lawsuit. On March 5, 1998, the FDA issued a proposed rule
applicable to companies that market "drugs of abuse test sample collection
systems". Under the proposed rule, companies engaged in the business of testing
for drugs of abuse using a test (screening assay) previously recognized by the
FDA would be able to market their test sample collection systems without
pre-market approval or clearance by the FDA so long as the test is conducted at
a laboratory that is recognized by laboratory certification agencies designated
by the FDA and certain labeling and product information procedures are followed.
To date, the FDA has recognized urine-screening assays that existed prior to the
1976 Medical Device Amendments to the Federal Food, Drug and Cosmetic Act, as
well as subsequent assays which have demonstrated substantial equivalence to
such previously existing assays. Under the FDA's proposed rule, companies
engaged in the business of testing for drugs of abuse using assays not yet
recognized by the FDA would be required to submit their assay to the FDA for
recognition prior to marketing. In addition, the laboratory performing the tests
would be required to be certified by a recognized agency. In the proposed rule,
the FDA states that it intends to implement the proposed new policy through
notice and comment rulemaking. The proposed rule includes a transitional period
of one year following the publication of a final rule in order for companies not
currently in compliance with the proposed requirements to obtain the necessary
data they need for submission to the FDA. As of March 15, 2000, a final rule had
not yet been published. There is a risk that, if the rule as proposed becomes
final, the Company may be required to apply to the FDA for recognition of the
Company's screening assays, and if such application were denied (and if such
denial were upheld on appeal), the Company's business would be materially
adversely affected. The Company believes that its proprietary method of
detecting drugs of abuse using hair samples includes accurate and reliable
screening assays and should, therefore, be recognized by the FDA if necessary.
However, the Company maintains that the FDA lacks statutory authority to
regulate its hair testing service as a medical device.

SCIENTIFIC ADVISORY BOARD

The Company has established a Scientific Advisory Board which consults with
management of the Company to examine and evaluate the progress of the Company's
research and development activities, to promote independent validation studies
of the Company's patented hair analysis method technology, and to assist in
accelerating acceptance of the technology in both the public and private
sectors. The Chairman of the Scientific Advisory Board is Dr. Robert DuPont. Dr.
DuPont's career has included numerous positions in the psychiatric and substance
abuse field, including Director, Special Action Office for Drug Abuse Prevention
- - The White House; the first Director, National Institute on Drug Abuse;
President, American Council for Drug Education; and President, Phobia Society of
America. Dr. DuPont has received several national awards and presently serves as
President: Institute for behavior and Health, Inc.; Vice President, Bensinger,
DuPont and Associates, a national drug and alcohol abuse consulting firm; and he
maintains a private practice in psychiatry. Dr. DuPont has also been granted
options to acquire shares of the Company's common stock. Other members of the
Scientific Advisory Board are Edward C. Senay, M.D., a Professor in the
Department of Psychiatry at the University of Chicago, and Arthur McBay, Ph.D.,
a Forensic Toxicologist and former Professor of Pharmacy at the University of
North Carolina.

RESEARCH AND DEVELOPMENT

The Company is continuously engaged in research and development activities.
During the years ended December 31, 1999, 1998 and 1997, $526,212, $499,895, and
$437,626, respectively, were expended for research and development. The Company
continues to perform research activities to develop new products and services
and to improve existing products and services utilizing the Company's
proprietary technology.


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<PAGE>   9


Additional research using the Company's proprietary technology is being
conducted by outside research organizations through government-funded studies.

The Company's research includes "controlled studies" to determine the advantages
of hair testing in the forensic and criminal justice markets. The Company has
also furnished technical assistance to several distinguished independent
researchers whose studies have been funded through government grants. Many such
studies are currently in progress. The Company continues to conduct its own
research toward the development of new inventions, services and products derived
from the Company's patented technology.

SOURCES AND AVAILABILITY OF RAW MATERIALS

Since its inception, the Company has purchased raw materials for its laboratory
services from outside suppliers. The most critical of these raw materials are
the radio-labeled drugs which the Company purchases from a single supplier,
although other suppliers of radio-labeled drugs exist. The Company has entered
into an agreement with its principal supplier to purchase certain proprietary
information regarding the manufacture of such radio-labeled drugs owned by the
supplier in the event that the supplier ceases to be able to supply such
radio-labeled drugs to the Company.

EMPLOYEES

As of December 31, 1999, the Company had 123 full-time equivalent employees, of
whom four full-time employees were in research and development. None of the
Company's employees is subject to a collective bargaining agreement.

ITEM 2.   PROPERTIES.

The Company maintains its corporate office and northeast sales office at 1280
Massachusetts Avenue, Cambridge, Massachusetts; the office is leased through
September 2003.

The Company leases 18,000 square feet of space in Culver City, California, for
laboratory purposes. This facility is leased through December 31, 2005 with an
option to renew for an additional two years. The Company also leases an
additional 5,400 square feet of space in Culver City, California for customer
service and information technology purposes. This office space is leased through
December 31, 2005.

ITEM 3.   LEGAL PROCEEDINGS.

The Company is involved in various suits and claims in the ordinary course of
business. The Company does not believe that the disposition of any such suits or
claims will have a material adverse effect on the continuing operations or
financial position of the Company.

ITEM 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

Not applicable.


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<PAGE>   10


                                     PART II
                                     -------

ITEM 5.   MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED SHAREHOLDER MATTERS.

The Company's common stock is traded on the American Stock Exchange under the
symbol "PMD". As of March 15, 2000, there were 406 record holders of the
Company's common stock. The following table sets forth for the periods indicated
the range of prices for the Company's common stock as reported by the American
Stock Exchange and dividends declared by the Company.

<TABLE>
<CAPTION>
Calendar Period                                 High                       Low                    Dividends
- ---------------                                 ----                       ---                    ---------

<S>                                           <C>                        <C> <C>                   <C>
1999
- ----
Fourth Quarter                                $ 5                        $ 4 1/8                   $ 0.04
Third Quarter                                 $ 5 1/8                    $ 4 1/8                   $ 0.04
Second Quarter                                $ 5 3/8                    $ 4                       $ 0.04
First Quarter                                 $ 5 5/16                   $ 4                       $ 0.04


1998
- ----
Fourth Quarter                                $ 5 1/8                    $ 4 1/16                  $ 0.03
Third Quarter                                 $ 5 5/16                   $ 4 1/8                   $ 0.03
Second Quarter                                $ 5 7/8                    $ 4 3/4                   $ 0.03
First Quarter                                 $ 6                        $ 5 5/16                  $ 0.02
</TABLE>

Future cash dividends may be declared at the discretion of the Board of
Directors.

ITEM 6.   SELECTED FINANCIAL DATA

The following selected financial data has been derived from the financial
statements of the Company and should be read in conjunction with, and is
qualified in its entirety by reference to, the financial statements and related
notes thereto.

<TABLE>
<CAPTION>
                                                                         AS OF AND FOR THE YEARS ENDED
                                                        ----------------------------------------------------------------
                                                                                  DECEMBER 31,
                                                        ----------------------------------------------------------------
                                                         1999          1998          1997           1996          1995
                                                         ----          ----          ----           ----          ----
                                                                 (IN THOUSANDS, EXCEPT FOR PER SHARE DATA)
<S>                                                     <C>           <C>           <C>            <C>           <C>
Revenue                                                 $19,623       $17,670       $15,398        $12,214       $10,111
Gross profit                                            $11,169       $10,201       $ 9,341        $ 7,233       $ 5,422
Income from operations                                  $ 3,547       $ 3,307       $ 3,056        $ 2,409       $ 1,301
Net income                                              $ 2,326       $ 2,397       $ 2,501        $ 2,492       $ 1,559
Basic net income per share                              $  0.11       $  0.11       $  0.11        $  0.12       $  0.07
Diluted net income per share                            $  0.11       $  0.11       $  0.11        $  0.11       $  0.07
Total Assets                                            $14,191       $19,083       $18,855        $15,745       $10,217
Working Capital                                         $ 8,184       $11,609       $13,090        $11,403       $ 6,789
Shareholders' Equity                                    $11,806       $15,883       $16,733        $14,296       $ 9,484
Cash dividends declared per
   common share                                         $  0.16       $  0.11       $  0.08        $  0.02            --
</TABLE>


                                       10
<PAGE>   11


ITEM 7.   MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
RESULTS OF OPERATIONS.

FACTORS THAT MAY AFFECT FUTURE RESULTS

From time to time, information provided by the Company or statements made by its
employees may contain "forward-looking" information which involves risks and
uncertainties. In particular, statements contained in this report which are not
historical facts (including, but not limited to, the Company's expectations
regarding revenues, business strategy, anticipated operating results, cash
dividends and anticipated cash requirements) may be "forward-looking"
statements. The Company's actual results may differ from those stated in any
"forward-looking" statements. Factors that may cause such differences include,
but are not limited to, risks associated with the continued expansion of the
Company's sales and marketing network, development of markets for new products
and services offered by the Company, the economic health of principal customers
of the Company, financial and operational risks associated with possible
expansion of testing facilities used by the Company, government regulation
(including, but not limited to, Food and Drug Administration regulations),
competition and general economic conditions.

RESULTS OF OPERATIONS

Revenue was $19.6 million in 1999, as compared to $17.7 million in 1998 and
$15.4 million in 1997, representing increases of 11% in 1999 and 15% in 1998
above prior year levels. These increases were due primarily to increases in
volume from both new and existing clients of 10% in 1999 and 17% in 1998. An
average price increase of 1% also added to revenue growth in 1999 as the Company
added new customers that were not subject to volume discounts. The 17% increase
in volume in 1998 was offset by an average price decrease of 2% in 1998
primarily as the result of volume discounts granted to large customers. Gross
margin was 57% of sales in 1999 compared to 58% of sales in 1998 and 61% in
1997. The decrease in 1999 and 1998 was due primarily to the addition of
production capacity during the latter part of 1998, in anticipation of future
sample volume increases.

General and administrative ("G&A") expenses represented 16% of revenue in 1999
and 1998, as compared to 15% of revenue in 1997. G&A expenses increased by
$159,000 to $3.1 million from 1998 to 1999 and increased by $634,000 to $2.9
million from 1997 to 1998. The increase in G&A expenses for 1999 was due
primarily to greater personnel costs, costs related to the implementation of a
new billing system and increased facilities expenses (rent, taxes).
Approximately half of the 1998 increase was personnel related and consisted
primarily of additions to staff and costs pertaining to the introduction of a
401(k) retirement plan. Greater professional fees for legal and accounting
services also contributed to the increase for 1998.

Marketing and selling expenses for the year ended December 31, 1999 increased to
21% of revenue versus 20% in 1998 and 23% in 1997. Marketing and selling
expenses increased by $542,000 to $4.0 million from 1998 to 1999, and decreased
by $87,000 to $3.5 million from 1997 to 1998. The increase in 1999 was primarily
due to greater customer service and marketing costs resulting from the Company's
growth. Although the Company continued to expand marketing activities related to
the corporate market in 1998, total marketing and selling expenses decreased
from 1997 levels because a significant amount of expenditures made in the second
quarter of 1997 to initially penetrate the retail home testing market were
non-recurring. The Company expects to continue to aggressively promote its drug
testing services in future years in order to expand its client base.

Research and development expenses increased by $26,000 from 1998 to 1999 and
$62,000 from 1997 to 1998, but remained constant as a percentage of revenue at
3% in 1999, 1998 and 1997.


                                       11
<PAGE>   12


Net interest income decreased by $173,000 in 1999 as compared to 1998, due to
lower average investment balances in 1999 as compared to 1998 along with
decreased yields on these investments. Net interest income increased by $43,000
in 1998, as compared to 1997, due to slightly higher average investment balances
in 1998, as compared to 1997 and improved cash management procedures that were
put in place during 1998.

During 1999, the Company recorded a tax provision of $1.6 million, reflecting an
effective tax rate of 40.9%, as compared to tax provisions of $1.5 million and
$1.1 million and effective tax rates of 38.0% and 30.0% for the years ended
December 31, 1998 and December 31, 1997, respectively. The increases in the
effective tax rate in 1999 and 1998 resulted from the reduction in net operating
loss carryforwards available to offset the provision for income taxes, partially
offset by tax credits generated in 1998.

LIQUIDITY AND CAPITAL RESOURCES

At December 31, 1999, the Company had $5.8 million of cash, cash equivalents and
short-term investments, compared to $9.8 million at December 31, 1998. The
Company's operating activities generated net cash of $2.9 million in 1999, $5.0
million in 1998, and $2.1 million in 1997. Investing activities generated $3.7
million in 1999, and used $1.6 million in 1998 and $2.5 million in 1997.
Financing activities used $6.4 million in 1999, $3.3 million in 1998, and
$501,000 in 1997.

Operating cash flows decreased by $2.1 million in 1999 as compared to 1998, due
primarily to a significant decrease in deferred revenue, lesser decreases in
accounts payable and accrued expenses and an increase in accounts receivable.
Net income in 1999 was $71,000 less than the 1998 amount, which also contributed
to the decrease in operating cash flows for 1999. The non-cash effect of
depreciation and amortization in 1999, 1998 and 1997 was $1,323,000, $991,000,
and $696,000, respectively.

Capital expenditures in 1999 were $496,000, a decrease of $1.4 million from 1998
expenditures of $1.9 million. The expenditures related principally to new
equipment, including laboratory and computer equipment. The Company currently
plans to make capital expenditures of approximately $800,000 in 2000, primarily
in connection with the purchase of additional laboratory and computer equipment.
The Company believes that within the next two years it may be required to expand
its existing laboratory or develop a second laboratory, the cost of which is
currently believed to range from $2 million to $4 million.

During 1999, the Company repurchased a total of 638,800 shares for treasury at
an aggregate cost of $2.9 million. In 1998, 349,981 shares were repurchased for
treasury at an aggregate cost of $1.6 million.

The Company distributed $3,486,268 and $2,444,957 of cash dividends to its
shareholders in 1999 and 1998, respectively. The Company commenced paying cash
dividends in 1997 and distributed $2,194,832 (including $437,221 of dividends
declared in 1996) during the year ended December 31, 1997.

At December 31, 1999, the Company's principal sources of liquidity included $5.8
million of cash, cash equivalents and short-term investments. Management
currently believes that such funds, together with future operating profits,
should be adequate to fund anticipated working capital requirements and capital
expenditures in the near term. Depending upon the Company's results of
operations, its future capital needs and available marketing opportunities, the
Company may use various financing sources to raise additional funds. Such
sources could include joint ventures, issuance of common stock or debt
financing. At December 31, 1999, the Company had no debt.



                                       12
<PAGE>   13

IMPACT OF YEAR 2000 ISSUE

The Year 2000 issue results from computer programs written using two digits
rather than four to define the applicable year. Any of the Company's computer
programs or hardware and equipment that have date-sensitive software may
recognize a date using "00" as the year 1900 rather than the year 2000. This
could result in a system failure or miscalculations causing disruptions of
operations, including, among other things, a temporary inability to process
transactions, send invoices, or engage in similar normal business activities.

With regards to the Year 2000 issue, the Company has not experienced any
problems with any of the existing software used in its internal systems and
operations or with the various hardware and equipment components used in its
laboratory operations.

The Company has not experienced any material shipment delays from its major
product suppliers or any material payment delays from its major customers due to
Year 2000 issues. However, there can be no assurance that these third parties
will not experience Year 2000 problems or that any problems would not have a
material effect on the Company's business. Because the cost and timing of Year
2000 compliance by third parties such as suppliers, customers and service
providers is not within the Company's control, no assurance can be given with
respect to the cost or timing of such efforts or any potential adverse effects
on the Company of any failure by these third parties to achieve Year 2000
compliance.

ITEM 7A.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The following discussion about the Company's market risk disclosures involves
forward-looking statements. Actual results could differ materially from those
projected in the forward-looking statements. The Company is exposed to market
risk related to changes in interest rates. The Company does not use derivative
financial instruments for speculative or trading purposes.

Interest Rate Sensitivity. The Company maintains a short-term investment
portfolio consisting principally of securities issued by the U.S. Government
with an average maturity of less than six months. These held-to-maturity
securities are subject to interest rate risk and will fall in value if market
rates increase. If market interest rates were to increase immediately and
uniformly by 10 percent from levels at December 31, 1999, the fair value of the
portfolio would decline by an immaterial amount. The Company has the ability to
hold its fixed income investments until maturity, and therefore the Company
would not expect its operating results or cash flows to be affected to any
significant degree by the effect of a sudden change in market interest rates on
its securities portfolio.

ITEM 8.   FINANCIAL STATEMENT AND SUPPLEMENTARY DATA

The financial statements and financial statement schedule are included in this
report on pages F-1 through F-15.

ITEM 9.   CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND
FINANCIAL DISCLOSURE

None.


                                       13
<PAGE>   14


                                    PART III
                                    --------

ITEM 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT.

Following is a list that sets forth as of March 15, 2000 the names, ages and
positions within the Company of all of the Executive Officers of the Company
persons chosen to become executive officers of the Company, and the Directors of
the Company. Each such director has been nominated for reelection at the
Company's 2000 Annual Meeting, to be held on May 11, 2000 at 2:00 P.M. at the
Charles Hotel, 1 Bennett Street, Cambridge, Massachusetts.

<TABLE>
<CAPTION>
NAME                                        AGE                  POSITION
- ----                                        ---                  --------

<S>                                         <C>               <C>
Raymond C. Kubacki, Jr.                     55                Chief Executive
                                                              Officer, President,
                                                              Director

Werner A. Baumgartner, Ph.D.                64                Chairman of the
                                                              Board, Director

A. Clinton Allen                            56                Vice Chairman of
                                                              the Board, Director

Peter C. Monson                             44                Vice President,
                                                              Treasurer, Controller

William Thistle, Esq.                       50                Vice President,
                                                              General Counsel

Michael I. Schaffer, Ph.D                   55                Vice President,
                                                              Laboratory Operations

Michael J. Lamb                             50                Vice President, Sales

Donald F. Flynn                             60                Director,
                                                              Audit Committee member,
                                                              Options Committee member

Walter S. Tomenson, Jr.                     53                Director,
                                                              Audit Committee member,
                                                              Options Committee member

Fred J. Weinert                             52                Director,
                                                              Audit Committee member,
                                                              Options Committee member
</TABLE>

All Directors hold office until the next annual meeting of stockholders or until
their successors are elected. Officers serve at the discretion of the Board of
Directors.

Mr. Kubacki has served as President and Chief Executive Officer and as a
Director of the Company since July 1991. Prior to joining the Company, he served
as Vice President-National Accounts and Director of Sales and Marketing for
Reliance COMM/TEC Corporation, a subsidiary of Reliance Electric Co.

Dr. Baumgartner, a founder of the Company, has served as Chairman of the Board
and a Director of the Company since its organization in September 1986. Dr.
Baumgartner has served as the Company's Director of Scientific and Regulatory
Affairs since May 1989. Dr. Baumgartner received his Ph.D. in physical chemistry
in 1963 from the University of New South Wales, Sydney, Australia, and has been
engaged in physical


                                       14
<PAGE>   15


and biophysical chemistry research since 1960, holding research and teaching
positions at University of New South Wales; Long Beach State University; Jet
Propulsion Laboratory at California Institute of Technology; University of
California, Los Angeles; and University of Southern California. Dr. Baumgartner
has been the director of the Radioimmunoassay and In Vitro Laboratory of the
Nuclear Medicine Service, Veterans Administration Hospital, Wadsworth, Los
Angeles, California, since 1976, serving in such capacity on a part-time basis
since February 1987.

Mr. Allen has served as Vice Chairman and as a Director of the Company since
1989. He is also Chairman and Chief Executive Officer of A.C. Allen & Company,
Inc., an investment banking consulting firm located in Cambridge, Massachusetts.
He is a director of Swiss Army Brands, Inc., Legal Club of America, Inc.,
Steinway Musical Instruments, Inc., Response USA Inc., Diversified Corporate
Resources, Inc., and The DeWolfe Companies, Inc., where he serves as Vice
Chairman.

Mr. Monson joined the Company effective March 30, 1998 as Vice President,
Treasurer and Controller. From November 1996 until joining the Company, Mr.
Monson was a financial consultant to several different companies, most recently
with GTE Internetworking. From 1994 to 1996, Mr. Monson was Chief Financial
Officer of Bet Systems, Inc. From 1991 to 1994, Mr. Monson was the Corporate
Controller and Treasurer of Gamma International, Ltd., a publicly traded gaming
company.

Mr. Thistle joined the Company in September 1995 as Vice President and General
Counsel. Prior to joining the Company, he served as Associate General Counsel
for MGM Grand in Las Vegas from 1993 to 1995. From 1989 to 1993, Mr. Thistle was
Associate General Counsel for Harrah's Casino Resorts. Mr. Thistle is on the
Legal Advisory Board of the Institute for a Drug Free Workplace and is a board
member of the Drug and Alcohol Testing Industry Association ("DATIA").

Dr. Schaffer joined the Company in April 1999 as Vice President of Laboratory
Operations. Prior to joining the Company, he served as Director of Toxicology,
Technical Manager and Responsible Person for the Leesburg, Florida laboratory of
SmithKline Beecham Clinical Laboratories, from 1990 to 1999. Dr. Schaffer has
been an inspector for the Substance Abuse and Mental Health Services
Administration's National Laboratory Certification Program since 1989. Dr.
Schaffer was also a member of the Board of Directors of the American Board of
Forensic Toxicologists from 1990 to 1999.

Mr. Lamb joined the Company in June 1997 as Vice President, Sales. Prior to
joining the Company, he served as Director, Sales and Marketing for Polaroid
Corporation located in Cambridge, Massachusetts, from 1990 to 1996. From 1986 to
1990, Mr. Lamb was Director, National Accounts for Polaroid Corporation, U.S.A.

Mr. Flynn has been the sole stockholder of Flynn Enterprises, Inc., a venture
capital, hedging and consulting firm based in Chicago, Illinois since its
inception in February 1988. He was the Vice Chairman of the Blue Chip Casino,
Inc., an owner and operator of a riverboat gaming vessel in Michigan City,
Indiana from February 1997 until November 1999 when Blue Chip was sold to Boyd
Gaming Corporation. Mr. Flynn also was Chairman of the Board from July 1992
until February 1996 and Chief Executive Officer from July 1992 until May 1995 of
Discovery Zone, Inc., an operator of indoor entertainment and fitness facilities
for children. On March 25, 1996, Discovery Zone, Inc. filed a voluntary petition
under Chapter 11 of the U.S. Bankruptcy Code. Discovery Zone emerged from
bankruptcy with a Plan of Reorganization that was approved by the Bankruptcy
Court in July 1997. From 1972 to 1990, Mr. Flynn served in various positions
with Waste Management, Inc. including Senior Vice President and Chief Financial
Officer. Mr. Flynn serves as a Director of Extended Stay America, Inc., an owner
and operator of extended-stay lodging facilities. Mr. Flynn has been a director
of the Company since 1989.


                                       15
<PAGE>   16


Mr. Tomenson has been Managing Director and Chairman of Client Development of
Marsh, Inc. since 1998. From 1993 to 1998, he was chairman of FINPRO, the
financial services division of Marsh, Inc. In addition, he is a member of the
Board of Directors of Marsh, Inc. Mr. Tomenson is a Director of Ronald McDonald
House and a Trustee of the Children's Oncology Society of New York, Inc. He is a
Director of the Trinity College School Fund, Inc. He also serves on the
Executive Council of the Inner-City Scholarship Fund.

Mr. Weinert is the majority shareholder and serves as CEO of San Telmo, Inc.,
Barrington Services Group, Inc., San Telmo L.L.C. and H20 Plus, S.R.L. From 1989
to 1995, he was President of H20 Plus L.P., MW Partners, and Century
Entertainment Ltd. Previous to that, he was President of Waste Management
International, Inc. from 1983 to 1989. For the last 15 years he has served on
the Business Advisory Council for the University of Dayton. Mr. Weinert has been
a director of the Company since 1991.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

Based solely on its reviews of copies of reports filed pursuant to Section 16(a)
of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or
written representations from persons required to file such reports ("Reporting
Persons"), the Company believes that, all such filings required to be made by
such Reporting Persons were timely made in accordance with the requirements of
the Exchange Act

ITEM 11.  EXECUTIVE COMPENSATION

The information required by this item will be set forth in the Proxy Statement
of the Company relating to the 2000 Annual Meeting of Stockholders to be held on
May 11, 2000 and is incorporated herein by reference.


                                       16
<PAGE>   17


ITEM 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

The information required by this item will be set forth in the Proxy Statement
of the Company relating to the 2000 Annual Meeting of Stockholders to be held on
May 11, 2000 and is incorporated herein by reference.

ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

The information required by this item will be set forth in the Proxy Statement
of the Company relating to the 2000 Annual Meeting of Stockholders to be held on
May 11, 2000 and is incorporated herein by reference.


                                       17
<PAGE>   18


                                     PART IV
                                     -------

ITEM 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K.

<TABLE>
<CAPTION>
(a)  (1)  Financial Statements:                                                Page
                                                                               ----

<S>                                                                             <C>
          Report of Independent Public Accountants                              F-1

          Balance Sheets as of December 31, 1999 and 1998                       F-2

          Statements of Income for the Years

          Ended December 31, 1999, 1998 and 1997                                F-3

          Statements of Shareholders' Equity for the Years

          Ended December 31, 1999, 1998 and 1997                                F-4

          Statements of Cash Flows for the Years

          Ended December 31, 1999, 1998 and 1997                                F-5

          Notes to Financial Statements                                         F-6

     (2)  Schedules

          None

     (3)  Exhibits (see the Index to Exhibits included elsewhere in this Report)

(b)       REPORTS ON FORM 8-K

          None
</TABLE>


<PAGE>   19


                                   SIGNATURES

Pursuant to the requirements of Section 13 or 15 (d) of the Securities Exchange
Act of 1934, the registrant has duly caused this Report to be signed on its
behalf by the undersigned, thereunto duly authorized.

                                                PSYCHEMEDICS CORPORATION

                                                By: /s/ Raymond C. Kubacki, Jr.
                                                   -----------------------------
                                                Raymond C. Kubacki, Jr.
                                                President and Chief Executive
                                                 Officer

Date:     March 24, 2000

Pursuant to the requirements of the Securities Exchange Act of 1934, this Report
has been signed below by the following persons on behalf of the Registrant and
in the capacities and on the dates indicated.

/s/ Raymond C. Kubacki, Jr.                          March 24, 2000
- ------------------------------------
Raymond C. Kubacki, Jr.
President and Chief Executive
Officer, Director
(Principal Executive Officer)

/s/ Peter C. Monson                                  March 24, 2000
- ------------------------------------
Peter C. Monson
Vice President, Treasurer, & Controller
(Principal Financial and Accounting Officer)

/s/ Werner A. Baumgartner, Ph.D.                     March 24, 2000
- ------------------------------------
Werner A. Baumgartner, Ph.D.
Director

/s/ A. Clinton Allen                                 March 24, 2000
- ------------------------------------
A. Clinton Allen
Director

/s/ Donald F. Flynn                                  March 24, 2000
- ------------------------------------
Donald F. Flynn
Director

/s/ Walter S. Tomenson, Jr.                          March 24, 2000
- ------------------------------------
Walter S. Tomenson, Jr.
Director

/s/ Fred J. Weinert                                  March 24, 2000
- ------------------------------------
Fred J. Weinert
Director


                                       19
<PAGE>   20


                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS
                    ----------------------------------------

To Psychemedics Corporation:

We have audited the accompanying balance sheets of Psychemedics Corporation (a
Delaware corporation) as of December 31, 1999 and 1998 and the related
statements of income, shareholders' equity and cash flows for each of the three
years in the period ended December 31, 1999. These financial statements are the
responsibility of the Company's management. Our responsibility is to express an
opinion on these financial statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to obtain reasonable assurance about whether the financial statements are free
of material misstatement. An audit includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial statements. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.

In our opinion, the financial statements referred to above present fairly, in
all material respects, the financial position of Psychemedics Corporation as of
December 31, 1999 and 1998 and the results of its operations and its cash flows
for each of the three years in the period ended December 31, 1999 in conformity
with accounting principles generally accepted in the United States.


                                                        ARTHUR ANDERSEN LLP


Boston, Massachusetts
February 8, 2000


                                      F-1
<PAGE>   21


                            PSYCHEMEDICS CORPORATION
                                 BALANCE SHEETS

<TABLE>
<CAPTION>
                                                                                   DECEMBER 31,
                                                                         -----------------------------------
                                                                             1999                   1998
                                                                             ----                   ----
<S>                                                                      <C>                    <C>
                                     ASSETS
CURRENT ASSETS:
    Cash and cash equivalents                                            $    899,387           $    724,738
    Short-term investments                                                  4,938,463              9,088,436
    Accounts receivable, net of allowance for doubtful accounts
      of $312,169 and $377,000 in 1999 and 1998, respectively               3,219,511              3,075,619
    Laboratory supplies                                                       449,103                510,016
    Deferred tax asset                                                        337,752                585,000
    Prepaid expenses and other current assets                                 557,276                482,388
                                                                         ------------           ------------
       Total current assets                                                10,401,492             14,466,197
                                                                         ------------           ------------
PROPERTY AND EQUIPMENT, AT COST:
    Computer software                                                       1,205,840              1,205,840
    Office furniture and equipment                                          1,510,647              1,277,519
    Laboratory equipment                                                    5,144,292              4,968,196
    Leasehold improvements                                                    711,707                679,810
                                                                         ------------           ------------
                                                                            8,572,486              8,131,365
    Less - Accumulated depreciation and amortization                        5,154,038              3,949,128
                                                                         ------------           ------------
                                                                            3,418,448              4,182,237
                                                                         ------------           ------------
OTHER ASSETS - NET                                                            370,965                434,925
                                                                         ------------           ------------
                                                                         $ 14,190,905           $ 19,083,359
                                                                         ============           ============
                      LIABILITIES AND SHAREHOLDERS' EQUITY
CURRENT LIABILITIES:
    Accounts payable                                                     $    512,580           $    675,072
    Accrued expenses                                                          473,725                582,754
    Accrued income taxes                                                      369,065                162,357
    Deferred revenue                                                          862,088              1,436,667
                                                                         ------------           ------------
       Total current liabilities                                            2,217,458              2,856,850
                                                                         ------------           ------------
DEFERRED TAX LIABILITY                                                        167,520                344,000
COMMITMENTS (Note 6)
SHAREHOLDERS' EQUITY:
    Preferred stock, $.005 par value; authorized 1,000,000
      shares; none outstanding                                                     --                     --
    Common stock, $.005 par value; authorized 50,000,000
      shares; issued and outstanding 22,612,440 and 22,607,290
      shares  in 1999 and 1998, respectively                                  113,062                113,036
    Paid-in capital                                                        24,414,985             24,403,949
    Accumulated deficit                                                    (6,746,157)            (5,585,453)
    Less - Treasury stock, at cost; 1,172,464 shares in 1999
      and 533,664 shares in 1998                                           (5,580,293)            (2,645,232)
    Less - Receivable from officer                                           (395,670)              (403,791)
                                                                         ------------           ------------
       Total shareholders' equity                                          11,805,927             15,882,509
                                                                         ------------           ------------
                                                                         $ 14,190,905           $ 19,083,359
                                                                         ============           ============
</TABLE>
   The accompanying notes are an integral part of these financial statements.


                                      F-2
<PAGE>   22


                            PSYCHEMEDICS CORPORATION
                              STATEMENTS OF INCOME

<TABLE>
<CAPTION>
                                                              YEARS ENDED DECEMBER 31,
                                              ----------------------------------------------------

                                                 1999                 1998                 1997
                                                 ----                 ----                 ----


<S>                                          <C>                  <C>                  <C>
REVENUE                                      $19,622,625          $17,669,975          $15,398,952
COST OF REVENUE                                8,453,261            7,468,574            6,057,606
                                             -----------          -----------          -----------
     Gross profit                             11,169,364           10,201,401            9,341,346
                                             -----------          -----------          -----------

EXPENSES:
     General and administrative                3,067,062            2,907,803            2,273,780
     Marketing and selling                     4,029,219            3,486,929            3,573,920
     Research and development                    526,212              499,895              437,626
                                             -----------          -----------          -----------
                                               7,622,493            6,894,627            6,285,326
                                             -----------          -----------          -----------
     Income from operations                    3,546,871            3,306,774            3,056,020
INTEREST INCOME, net                             387,693              560,235              517,133
                                             -----------          -----------          -----------

INCOME BEFORE PROVISION
     FOR INCOME TAXES                          3,934,564            3,867,009            3,573,153
PROVISION FOR INCOME TAXES                     1,609,000            1,470,000            1,072,000
                                             -----------          -----------          -----------

NET INCOME                                   $ 2,325,564          $ 2,397,009          $ 2,501,153
                                             ===========          ===========          ===========

BASIC NET INCOME PER SHARE                   $      0.11          $      0.11          $      0.11
                                             ===========          ===========          ===========

DILUTED NET INCOME PER SHARE                 $      0.11          $      0.11          $      0.11
                                             ===========          ===========          ===========

WEIGHTED AVERAGE COMMON SHARES
     OUTSTANDING                              21,823,650           22,205,626           21,963,116

WEIGHTED AVERAGE COMMON SHARES
     OUTSTANDING, ASSUMING DILUTION           22,055,990           22,586,705           22,540,841
</TABLE>


The accompanying notes are an integral part of these financial statements.


                                      F-3
<PAGE>   23


                            PSYCHEMEDICS CORPORATION
                       STATEMENTS OF SHAREHOLDERS' EQUITY

<TABLE>
<CAPTION>
                                           COMMON STOCK                                                   TREASURY STOCK
                                     -------------------------                                      ------------------------
                                                    $0.005         PAID-IN       ACCUMULATED
                                       SHARES      PAR VALUE       CAPITAL         DEFICIT            SHARES        COST
                                     ---------------------------------------------------------------------------------------

<S>                                  <C>          <C>            <C>            <C>                   <C>      <C>
BALANCE, December 31, 1996           21,758,087   $    108,790   $ 20,722,137   $ (6,281,047)         66,381   $   (254,063)

   Exercise of stock options,
       including tax benefits           624,633          3,123      2,859,412             --              --             --
   Cash dividends declared
       ($0.08 per share)                     --             --             --     (1,757,611)             --             --
   Acquisition of treasury stock             --             --             --             --         117,302       (751,376)
   Net income                                --             --             --      2,501,153              --             --
                                     ---------------------------------------------------------------------------------------
BALANCE, December 31, 1997           22,382,720        111,913     23,581,549     (5,537,505)        183,683     (1,005,439)

   Exercise of stock options,
       including tax benefits           224,570          1,123        822,400             --              --             --
   Payments on receivable from
       officer                               --             --             --             --              --             --
   Cash dividends declared
       ($0.11 per share)                     --             --             --     (2,444,957)             --             --
   Acquisition of treasury stock             --             --             --             --         349,981     (1,639,793)
   Net income                                --             --             --      2,397,009              --             --
                                     ---------------------------------------------------------------------------------------
BALANCE, December 31, 1998           22,607,290        113,036     24,403,949     (5,585,453)        533,664     (2,645,232)
                                     ---------------------------------------------------------------------------------------

   Exercise of stock options,
       including tax benefits             5,150             26         11,036             --              --             --
   Payments on receivable from
       officer                               --             --             --             --              --             --
   Cash dividends declared
       ($0.16 per share)                     --             --             --     (3,486,268)             --             --
   Acquisition of treasury stock             --             --             --             --         638,800     (2,935,061)
   Net income                                --             --             --      2,325,564              --             --
                                     ---------------------------------------------------------------------------------------
BALANCE, December 31, 1999           22,612,440   $    113,062   $ 24,414,985   $ (6,746,157)      1,172,464   $ (5,580,293)
                                     =======================================================================================
</TABLE>


<TABLE>
<CAPTION>
                                      RECEIVABLE
                                     FROM OFFICER      TOTAL
                                     ---------------------------

<S>                                    <C>         <C>
BALANCE, December 31, 1996                   --    $ 14,295,817

   Exercise of stock options,
       including tax benefits          (417,611)      2,444,924
   Cash dividends declared
       ($0.08 per share)                     --      (1,757,611)
   Acquisition of treasury stock             --        (751,376)
   Net income                                --       2,501,153

                                   ----------------------------
BALANCE, December 31, 1997             (417,611)     16,732,907

   Exercise of stock options,
       including tax benefits                --         823,523
   Payments on receivable from
       officer                           13,820          13,820
   Cash dividends declared
       ($0.11 per share)                     --      (2,444,957)
   Acquisition of treasury stock             --      (1,639,793)
   Net income                                --       2,397,009

                                   ----------------------------
BALANCE, December 31, 1998             (403,791)     15,882,509
                                   ----------------------------

   Exercise of stock options,
       including tax benefits                --          11,062
   Payments on receivable from
       officer                            8,121           8,121
   Cash dividends declared
       ($0.16 per share)                     --      (3,486,268)
   Acquisition of treasury stock             --      (2,935,061)
   Net income                                --       2,325,564

                                   ----------------------------
BALANCE, December 31, 1999         $   (395,670)   $ 11,805,927
                                   ============================
</TABLE>


   The accompanying notes are an integral part of these financial statements.


                                      F-4
<PAGE>   24


                            PSYCHEMEDICS CORPORATION
                            STATEMENTS OF CASH FLOWS

<TABLE>
<CAPTION>
                                                                                      YEARS ENDED DECEMBER 31,
                                                                     -------------------------------------------------------
                                                                         1999                  1998                  1997
                                                                         ----                  ----                  ----
<S>                                                                  <C>                   <C>                   <C>
CASH FLOWS FROM OPERATING ACTIVITIES:
   Net income                                                        $ 2,325,564           $ 2,397,009           $ 2,501,153
   Adjustments to reconcile net income to net
    cash provided by operating activities:
     Depreciation and amortization                                     1,323,411               990,807               696,514
     Deferred income taxes                                                70,768               139,000              (380,000)
     Changes in current assets and liabilities:
      Accounts receivable                                               (143,892)              708,869            (1,127,072)
      Laboratory supplies                                                 60,913                (9,691)             (269,548)
      Prepaid expenses and other current assets                          (74,888)               33,486              (386,046)
      Accounts payable                                                  (162,492)              478,813              (199,175)
      Accrued expenses                                                  (109,029)              361,934              (111,424)
      Accrued income taxes                                               206,708               (54,886)              (18,040)
      Deferred revenue                                                  (574,579)              (51,343)            1,439,485
                                                                     -----------           -----------           -----------
       Net cash provided by operating activities                       2,922,484             4,993,998             2,145,847
                                                                     -----------           -----------           -----------

CASH FLOWS FROM INVESTING ACTIVITIES:
   Net sales (purchases) of short-term investments                     4,149,973               357,982            (1,075,691)
   Purchases of property and equipment                                  (495,662)           (1,889,849)           (1,412,695)
   Increase in other assets                                                   --               (75,128)              (33,717)
                                                                     -----------           -----------           -----------
       Net cash provided by (used in) investing activities             3,654,311            (1,606,995)           (2,522,103)
                                                                     -----------           -----------           -----------


CASH FLOWS FROM FINANCING ACTIVITIES:
   Proceeds from the exercise of stock options, including
       tax benefits                                                       11,062               823,523             2,444,924
   Proceeds from the receivable from officer                               8,121                13,820                    --
   Dividends paid                                                     (3,486,268)           (2,444,957)           (2,194,828)
   Acquisition of treasury stock                                      (2,935,061)           (1,639,793)             (751,376)
                                                                     -----------           -----------           -----------
       Net cash used in financing activities                          (6,402,146)           (3,247,407)             (501,280)
                                                                     -----------           -----------           -----------


NET INCREASE (DECREASE) IN CASH AND CASH
       EQUIVALENTS                                                       174,649               139,596              (877,536)
CASH AND CASH EQUIVALENTS, beginning of year                             724,738               585,142             1,462,678
                                                                     -----------           -----------           -----------

CASH AND CASH EQUIVALENTS, end of year                               $   899,387           $   724,738           $   585,142
                                                                     ===========           ===========           ===========

Supplemental Disclosure of Cash Flow Information:
- -------------------------------------------------
       Cash paid for income taxes                                    $ 1,334,985           $ 1,073,000           $   156,000
                                                                     ===========           ===========           ===========

Supplemental Disclosure of Non-Cash Financing Activity:
- -------------------------------------------------------
       Issuance of common stock for receivable from officer          $        --           $        --           $   417,611
                                                                     ===========           ===========           ===========
</TABLE>


   The accompanying notes are an integral part of these financial statements.


                                      F-5
<PAGE>   25


                            PSYCHEMEDICS CORPORATION

                          NOTES TO FINANCIAL STATEMENTS

                                DECEMBER 31, 1999

1.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

     The Company

Psychemedics Corporation (the Company) was incorporated in 1986. The Company
utilizes a patented hair analysis method involving radioimmunoassay technology
to analyze human hair to detect abused substances. The founder of the Company
has granted to the Company an exclusive license to all his rights in this hair
analysis technology, including his rights to the drug extraction method (see
Note 3).

     Management Estimates and Uncertainties

The preparation of financial statements in conformity with generally accepted
accounting principles requires management to make estimates and assumptions that
affect the reported amounts of assets and liabilities and disclosure of
contingent assets and liabilities at the date of the financial statements and
the reported amounts of revenues and expenses during the reporting period.
Actual results could differ from those estimates.

The Company is subject to a number of risks and uncertainties similar to those
of other companies, such as those associated with the continued expansion of the
Company's sales and marketing network, development of markets for new products
and services offered by the Company, the economic health of principal customers
of the Company, financial and operational risks associated with possible
expansion of testing facilities used by the Company, government regulation
(including, but not limited to, Food and Drug Administration regulations),
competition and general economic conditions.

     Cash Equivalents and Short-Term Investments

The Company considers all highly liquid investments with original maturities of
90 days or less from the date of purchase to be cash equivalents. Cash
equivalents consist principally of money market accounts at December 31, 1999
and 1998.

The Company accounts for investment securities in accordance with Statement of
Financial Accounting Standards (SFAS) No. 115, Accounting for Certain
Investments in Debt and Equity Securities. Under SFAS No. 115, investments that
the Company has the positive intent and ability to hold to maturity are
classified as held-to-maturity and are reported at amortized cost, which
approximates fair market value. All short-term investments were classified as
held-to-maturity at December 31, 1999 and 1998. Short-term investments have
maturities between three months and one year and consist principally of
securities issued by the U.S. Government at December 31, 1999 and 1998.


                                      F-6
<PAGE>   26


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

At December 31, 1999 and 1998, held-to-maturity marketable securities consisted
of the following:
<TABLE>
<CAPTION>
                                                   1999                                    1998
                                      ------------------------------          ------------------------------
                                         Market            Amortized             Market            Amortized
                                         Value               Cost                Value               Cost
                                         ------            ---------             ------            ---------

<S>                                   <C>                 <C>                 <C>                 <C>
US Treasury obligations
   (maturity 3-8 months)              $  868,221          $  871,308          $3,444,330          $3,437,161
Federal agency obligations
   (maturity 3-9 months)               4,055,441           4,067,155           4,659,820           4,656,345
Commercial paper obligations
   (maturity 2 months)                        --                  --             995,149             994,930
                                      ------------------------------          ------------------------------
                                      $4,923,662          $4,938,463          $9,099,299          $9,088,436
                                      ==============================          ==============================
</TABLE>

     Property and Equipment

Property and equipment are stated at cost. Depreciation and amortization are
provided over the estimated useful lives of the assets, using the straight-line
method. The estimated useful lives of the assets are as follows:

<TABLE>
<CAPTION>
<S>                                                  <C>
         Computer software                           5 years
         Office furniture and equipment              5 to 7 years
         Laboratory equipment                        5 to 7 years
         Leasehold improvements                      Lesser of 5 years or life of lease
</TABLE>

     Other Assets

Other assets consist primarily of capitalized legal costs relating to patent
applications on the Company's drug extraction method. The Company is amortizing
the cost of these patents over 10 years from the date of grant. The Company
recorded amortization of $63,960 and $63,521 in 1999 and 1998, respectively. In
accordance with SFAS No. 121, Accounting for the Impairment of Long-Lived Assets
and for Long-Lived Assets to Be Disposed Of, the Company evaluates the
realizability of its patents based on estimated cash flows to be generated from
such assets as compared to the original estimates. To the extent an impairment
is identified, the Company will recognize a write-down of the related assets. To
date, no impairment has been identified.

     Revenue Recognition

Except as described herein, revenues from the Company's services are recognized
upon reporting of drug test results to the customer. Revenues related to sample
collection kits not returned for processing by customers are recognized when the
likelihood of the Company performing any service obligation is deemed remote.
During 1999, 1998, and 1997, the Company recorded $625,000, $599,000, and $0,
respectively, of revenue related to test kits that were sold for which the
Company's obligations to provide service was deemed remote. At December 31, 1999
and 1998, the Company had deferred revenue balances of approximately $862,000
and $1,437,000, respectively, reflecting payments for its personal drug testing
service received prior to the performance of the related test.



                                      F-7
<PAGE>   27


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

     Income Taxes

The Company accounts for income taxes in accordance with the provisions of SFAS
No. 109, Accounting for Income Taxes. This statement requires the Company to
recognize a current tax liability or asset for current taxes payable or
refundable and a deferred tax liability or asset for the estimated future tax
effects of temporary differences between the financial statement and tax
reporting of assets and liabilities to the extent that they are realizable.
Deferred tax expense (benefit) results from the net change in deferred tax
assets and liabilities during the year. A deferred tax valuation allowance is
required if it is more likely than not that all or a portion of the recorded
deferred tax assets will not be realized.

     Research and Development Expenses

The Company charges all research and development expenses to operations as
incurred.

     Concentration of Credit Risk

SFAS No. 105, Disclosure of Information About Financial Instruments with
Off-Balance-Sheet Risk and Financial Instruments with Concentrations of Credit
Risk, requires disclosure of any significant off-balance-sheet and credit risk
concentrations. The Company has no significant off-balance-sheet or
concentration of credit risk. Financial instruments that potentially subject the
Company to concentrations of credit risk are principally cash equivalents,
short-term investments and accounts receivable. The Company places its
investments in highly rated institutions. Concentration of credit risk with
respect to accounts receivable is limited to certain customers to whom the
Company makes substantial sales. To reduce risk, the Company routinely assesses
the financial strength of its customers and, as a consequence, believes that its
accounts receivable credit risk exposure is limited. The Company maintains an
allowance for potential credit losses but historically has not experienced any
significant losses related to individual customers or groups of customers in any
particular industry or geographic area.

     Significant Customers

No single customer accounted for greater than 10% of revenues in 1999 and 1998,
respectively. One of the Company's customers accounted for 10% of total revenues
in 1997. As of December 31, 1999 and 1998, the same customer accounted for 6%
and 10% of total accounts receivable, respectively.

     Basic and Diluted Net Income per Share

In accordance with SFAS No. 128, Earnings per Share, basic net income per share
is computed by dividing net income by the weighted average number of common
shares outstanding during the period. Diluted net income per share was computed
by dividing net income by the weighted average number of common and dilutive
common equivalent shares outstanding during the period. The number of dilutive
common equivalent shares outstanding during the period has been determined in
accordance with the treasury-stock method. Common equivalent shares consist of
common stock issuable upon the exercise of outstanding options.



                                      F-8
<PAGE>   28


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)


Basic and diluted weighted average common shares outstanding are as follows:

<TABLE>
<CAPTION>
                                              1999                1998               1997
                                              ----                ----               ----

<S>                                        <C>                 <C>                 <C>
Weighted average common shares
   outstanding                             21,823,650          22,205,626          21,963,116
Dilutive common equivalent shares             232,340             381,079             577,725
                                           ----------          ----------          ----------
Weighted average common shares
   outstanding, assuming dilution          22,055,990          22,586,705          22,540,841
                                           ==========          ==========          ==========
</TABLE>


As of December 31, 1999, 1998 and 1997, options to purchase 752,570, 553,666,
and 113,000 common shares, respectively, were outstanding but not included in
the dilutive common equivalent share calculation as their effect would have been
antidilutive.

     Financial Instruments

SFAS No. 107, Disclosures about Fair Value of Financial Instruments, requires
disclosure about the fair value of financial instruments. Financial instruments
consist principally of cash equivalents, short-term investments, accounts
receivable and accounts payable. The estimated fair value of these financial
instruments approximates their carrying value and, except for accounts
receivable, is based primarily on market quotes. The Company's cash equivalents
and short-term investments are generally money market accounts and securities
issued by the U.S. Government.

     Comprehensive Income

Effective January 1, 1998, the Company adopted the provisions of SFAS No. 130,
Reporting Comprehensive Income. SFAS No. 130 requires disclosure of all
components of comprehensive income on an annual and interim basis. Comprehensive
income is defined as the change in equity of a business enterprise during a
period from transactions and other events and circumstances from nonowner
sources. The Company's total comprehensive income was the same as reported net
income for all periods presented.

     Segment Reporting

The Company adopted SFAS No. 131, Disclosures About Segments of an Enterprise
and Related Information, in the fiscal year ended December 31, 1998. SFAS No.
131 establishes standards for reporting information regarding operating segments
in annual financial statements and requires selected information for those
segments to be presented in interim financial reports issued to stockholders.
SFAS No. 131 also establishes standards for related disclosures about products
and services and geographic areas. To date, the Company has managed its
operations as one segment, drug testing services. As a result, the financial
information disclosed herein materially represents all of the financial
information related to the Company's principal operating segment. Substantially
all of the Company's revenues are generated in the United States. All of the
Company's assets are located in the United States.

     Software Development Costs

In March 1998, the American Institute of Certified Public Accountants (AICPA)
issued Statement of Position (SOP) 98-1, Accounting for the Costs of Computer
Software Developed or Obtained for Internal Use. SOP 98-1 requires computer
software costs associated with internal use software to be charged to operations
as incurred until certain capitalization criteria have been met. The Company
adopted SOP 98-1 beginning January 1, 1998. SOP 98-1 had no effect upon
adoption. As of December 31, 1999 and 1998, $1,205,540 of software development
costs have been capitalized. During the years ended December 31, 1999, 1998 and
1997, $240,848, $43,930 and $20,848 of related amortization was charged to
operations, respectively.

     Derivative Instruments and Hedging Activities


                                      F-9
<PAGE>   29


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

In June 1999, the Financial Accounting Standards Board ("FASB") issued SFAS No.
137, Accounting for Derivative Financial Instruments and Hedging Activities -
Deferral of the Effective Date of FASB Statement No. 133, which defers the
effective date of SFAS No. 133 to all fiscal quarters of all fiscal years
beginning after June 15, 2000. SFAS No. 133, Accounting for Derivative
Instruments and Hedging Activities, establishes accounting and reporting
standards for derivative instruments, including certain derivative instruments
embedded in other contracts, and for hedging activities. It requires entities to
recognize all derivatives as either assets or liabilities in the statement of
financial position and to measure those instruments at fair value. The Company
does not anticipate the adoption of these statements to have a material impact
on its financial position or results of operations. As of December 31, 1999, the
Company did not have any derivatives or other financial instruments as defined
by SFAS No. 119, Disclosures about Derivative Financial Instruments and Fair
Value of Financial Instruments.

     Reclassifications

Certain amounts in the prior year's financial statements have been reclassified
to conform with the current year's presentation.

2.   RECEIVABLE FROM OFFICER

The amounts receivable from officer represent advances for the purchase of
common stock. The notes bear interest at 5.82% and 6.13% and are full recourse.
The notes, together with accrued interest, are payable approximately $197,000 on
November 12, 2000 and approximately $199,000 on January 6, 2001.


                                      F-10
<PAGE>   30


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

3.   ROYALTY AGREEMENTS

The Company has a royalty-free license from the founder for the proprietary
rights to the patented hair analysis technology used by the Company in its drug
testing services. The Company has two agreements to sublicense its technology,
which have not generated significant royalties to date.

4.   INCOME TAXES

The income tax provisions for the years ended December 31, 1999, 1998 and 1997
consist of the following:
<TABLE>
<CAPTION>
                        1999                 1998                  1997
                        ----                 ----                  ----
<S>                 <C>                  <C>                   <C>
Current -
   Federal          $ 1,181,000          $   998,000           $ 1,197,400
   State                357,000              333,000               254,600
                    -----------          -----------           -----------
                      1,538,000            1,331,000             1,452,000
                    -----------          -----------           -----------
Deferred -
   Federal               56,000              104,000              (290,300)
   State                 15,000               35,000               (89,700)
                    -----------          -----------           -----------
                         71,000              139,000              (380,000)
                    -----------          -----------           -----------

                    $ 1,609,000          $ 1,470,000           $ 1,072,000
                    ===========          ===========           ===========
</TABLE>

The provisions for income taxes differ from the amount computed by applying the
statutory federal income tax rate as follows:
<TABLE>
<CAPTION>
                                                              1999            1998            1997
                                                              ----            ----            ----

<S>                                                           <C>             <C>             <C>
Federal statutory rate                                        34.0%           34.0%           34.0%
Increase (decrease) resulting from -
   State tax provision, net of federal benefit                 6.3             5.9             6.3
   Utilization of net operating loss carryforwards
      previously not benefitted                                 --              --           (10.6)
   Utilization of tax credits                                 (1.3)           (5.7)             --
   Non-deductible expenses                                     1.9             3.8             3.6
   Other, net                                                   --              --            (3.3)
                                                              ----            ----            ----
Effective tax rate                                            40.9%           38.0%           30.0%
                                                              ====            ====            ====
</TABLE>

The components of the net deferred tax assets included in the accompanying
balance sheets are approximately as follows:

<TABLE>
<CAPTION>
                                                1999                1998
                                                ----                ----
<S>                                          <C>                 <C>
Deferred revenue                             $ 239,000           $ 442,000
Nondeductible reserves and accruals             99,000             143,000
Property basis differences                    (168,000)           (344,000)
                                             ---------           ---------
      Net asset                              $ 170,000           $ 241,000
                                             =========           =========
</TABLE>

The long term deferred tax liability on the Company's balance sheet principally
represents property basis differences.


                                      F-11
<PAGE>   31


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

5.   STOCK OPTIONS

The Company has various stock option plans under which options to acquire shares
of the Company's common stock may be granted to directors, officers and certain
employees of the Company. Options granted under the plans are non-qualified or
incentive stock options, and are granted at a price that is not less than the
fair market value of the common stock at the date of grant. These options have
lives of five or ten years and vest over periods from zero to ten years.

A summary of all stock option transactions for the years ended December 31,
1999, 1998 and 1997 is as follows (in thousands, except per share amounts):

<TABLE>
<CAPTION>
                                                                       WEIGHTED AVERAGE
                                             NUMBER OF SHARES           EXERCISE PRICE
                                             ----------------          ----------------
<S>                                              <C>                       <C>
Outstanding, December 31,1996                     1,907                     $   2.98
   Granted                                          173                         6.89
   Exercised                                       (625)                        2.48
   Terminated                                       (31)                        4.16
                                                 ------                     --------
Outstanding, December 31,1997                     1,424                         4.02
   Granted                                          337                         5.17
   Exercised                                       (225)                        2.27
   Terminated                                       (70)                        5.14
                                                 ------                     --------
Outstanding, December 31,1998                     1,466                         4.43
   Granted                                          391                         4.45
   Exercised                                         (5)                        2.82
   Terminated                                      (110)                        5.66
                                                 ------                     --------
Outstanding, December 31,1999                     1,742                     $   4.37
                                                 ======                     ========
Exercisable, December 31,1999                     1,122                     $   4.07
                                                 ======                     ========
Exercisable, December 31,1998                       903                     $   3.93
                                                 ======                     ========
Exercisable, December 31,1997                       758                     $   3.04
                                                 ======                     ========
</TABLE>

The following table summarizes information about stock options outstanding at
December 31, 1999 (in thousands, except per share amounts):

<TABLE>
<CAPTION>
                                     OPTIONS OUTSTANDING                             OPTIONS EXERCISABLE
                      ---------------------------------------------------         ----------------------------
                       NUMBER         WEIGHTED AVERAGE        WEIGHTED            NUMBER           WEIGHTED
 EXERCISE PRICE          OF              REMAINING             AVERAGE              OF              AVERAGE
     RANGE            OPTIONS         CONTRACTUAL LIFE     EXERCISE PRICE         OPTIONS       EXERCISE PRICE
 --------------       -------         ----------------     --------------         -------       --------------
<S>                    <C>                  <C>                <C>                 <C>              <C>
     $1.85               221                 3.93               $1.85               221              $1.85
  2.82 - 3.63            397                 5.10                3.00               397               3.00
  4.28 - 6.22          1,033                 8.01                5.16               438               5.69
  7.06 - 7.69             91                 7.33                7.41                66               7.30
</TABLE>

The weighted average remaining contractual life of options outstanding at
December 31, 1999, 1998 and 1997 was 6.79 years, 7.14 years, and 7.63 years,
respectively.



                                      F-12
<PAGE>   32


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)


     Accounting for Stock-Based Compensation

SFAS No. 123, Accounting for Stock-Based Compensation, requires the measurement
of the fair value of stock options or warrants to be included in the statement
of income or disclosed in the notes to financial statements. The Company has
determined that it will continue to account for stock-based compensation for
employees under Accounting Principles Board Opinion No. 25, Accounting for Stock
Issued to Employees, and elect the disclosure-only alternative under SFAS No.
123. The Company has computed the value of options using the Black-Scholes
option pricing model prescribed by SFAS No. 123.

The assumptions used and the weighted average information for the years ended
December 31, 1998, 1997 and 1996 are as follows:

<TABLE>
<CAPTION>
                                                               1999              1998               1997
                                                               ----              ----               ----
<S>                                                             <C>               <C>                <C>
Risk-free interest rates                                        5.54%             5.15%              6.32%
Expected dividend yield                                          3.5%                2%                 1%
Expected lives                                                5 years           5 years            5 years
Expected volatility                                            42.23%            42.68%             69.70%
Weighted average grant-date fair value of
   options granted during the period                           $1.62             $2.14              $4.44
</TABLE>

Had compensation cost for the Company's stock option plans been determined
consistent with SFAS No. 123, net income and basic and diluted net income per
share would have been approximately as follows:

<TABLE>
<CAPTION>
                                                            1999                 1998                 1997
                                                            ----                 ----                 ----
<S>                                                      <C>                  <C>                  <C>
As reported -
   Net income                                            $2,325,564           $2,397,009           $2,501,153
   Basic net income per share                            $     0.11           $     0.11           $     0.11
   Diluted net income per share                          $     0.11           $     0.11           $     0.11
Pro forma -
   Net income                                            $1,719,967           $1,713,342           $1,892,035
   Basic net income per share                            $     0.08           $     0.08           $     0.09
   Diluted net income per share                          $     0.08           $     0.08           $     0.08
</TABLE>

6.   COMMITMENTS

     Lease Agreements

The Company leases certain of its facilities and equipment under operating lease
agreements expiring on various dates through December 2005. Total minimum lease
payments, including scheduled increases, are charged to operations on the
straight-line basis over the life of the respective lease. Rent expense for the
years ended December 31, 1999, 1998 and 1997 was approximately $473,000,
$441,000, and $475,000, respectively.


                                      F-13
<PAGE>   33


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

At December 31, 1999, minimum commitments remaining under lease agreements were
as follows:

<TABLE>
<CAPTION>
                                                                             Amount
                                                                             ------
<S>                                                                       <C>
         Years ending December 31:
                  2000                                                    $  503,000
                  2001                                                       472,000
                  2002                                                       460,000
                  2003                                                       440,000
                  2004                                                       341,000
                  Thereafter                                                 354,000
                                                                          ----------
                                                                          $2,570,000
                                                                          ==========
</TABLE>

7.   EMPLOYEE BENEFIT PLAN

On November 1, 1997, the Company adopted the Psychemedics Corporation 401(k)
Savings and Retirement Plan (the 401(k) Plan). The 401(k) Plan is a qualified
defined contribution plan in accordance with Section 401(k) of the Internal
Revenue Code. All employees over the age of 21 who have completed one year of
service are eligible to make pre-tax contributions up to a specified percentage
of their compensation. Under the 401(k) Plan, the Company may, but is not
obligated to, match a portion of the employees' contribution up to a defined
maximum. A matching contribution of $99,683 and $94,111 was made in 1999 and
1998, respectively, while no contribution was made in 1997.

8.   ACCRUED EXPENSES

Accrued expenses consist of the following:

<TABLE>
<CAPTION>
                                                                         December 31,
                                                            -------------------------------------
                                                               1999                        1998
                                                               ----                        ----
<S>                                                         <C>                         <C>
Accrued payroll and employee benefits                       $ 371,095                   $ 246,277
Other accrued expenses                                        102,630                     336,477
                                                            ---------                   ---------
                                                            $ 473,725                   $ 582,754
                                                            =========                   =========
</TABLE>


                                      F-14
<PAGE>   34


                            PSYCHEMEDICS CORPORATION
                   NOTES TO FINANCIAL STATEMENTS - (CONTINUED)

9.   SELECTED QUARTERLY FINANCIAL DATA (UNAUDITED)

The following are selected quarterly financial data for the years ended December
31, 1999 and 1998:

<TABLE>
<CAPTION>
                                                                               QUARTER ENDED
                                                  --------------------------------------------------------------------------
                                                    MARCH 31,            JUNE 30,          SEPTEMBER 30,        DECEMBER 31,
                                                      1999                 1999                1999                 1999
                                                   ----------           ----------         -------------        ------------
<S>                                                <C>                  <C>                 <C>                  <C>
Revenues                                           $4,680,257           $5,854,999          $4,904,275           $4,183,094
Gross profit                                        2,737,158            3,567,940           2,708,310            2,155,956
Income from operations                                844,764            1,535,736             916,450              249,921
Net income                                            567,239              960,844             596,595              200,886
Basic net income per share                               0.03                 0.04                0.03                 0.01
Diluted net income per share                             0.03                 0.04                0.03                 0.01
</TABLE>

<TABLE>
<CAPTION>
                                                                               QUARTER ENDED
                                                   -------------------------------------------------------------------------
                                                    MARCH 31,            JUNE 30,          SEPTEMBER 30,        DECEMBER 31,
                                                      1998                 1998                1998                 1998
                                                   ----------           ----------         -------------        ------------
<S>                                                <C>                  <C>                 <C>                  <C>
Revenues                                           $4,121,903           $4,834,720          $4,571,820           $4,141,532
Gross profit                                        2,427,015            2,924,394           2,623,795            2,226,197
Income from operations                                944,034            1,175,911             826,078              360,751
Net income                                            641,278              782,186             575,409              398,136
Basic net income per share                               0.03                 0.04                0.03                 0.02
Diluted net income per share                             0.03                 0.03                0.03                 0.02
</TABLE>

10.  ALLOWANCE FOR DOUBTFUL ACCOUNTS

A summary of the allowance for doubtful accounts is as follows:

<TABLE>
<CAPTION>
                                                             1999                 1998                 1997
                                                             ----                 ----                 ----
<S>                                                       <C>                  <C>                  <C>
Balance, beginning of period                              $ 377,000            $ 264,429            $ 163,991
Provision for doubtful accounts                             178,377              165,000              162,000
Write-offs                                                 (243,208)             (52,429)             (61,562)
                                                          ---------            ---------            ---------
Balance, end of period                                    $ 312,169            $ 377,000            $ 264,429
                                                          ---------            ---------            ---------
</TABLE>


                                      F-15
<PAGE>   35


                            PSYCHEMEDICS CORPORATION

                                      10-K

                                INDEX TO EXHIBITS

<TABLE>
<CAPTION>
Exhibit
Number                              Description
- -------                             -----------

<S>               <C>
3                 Articles of Incorporation and By-Laws
                  -------------------------------------

3.1               Certificate of Incorporation filed
                  September 24, 1986 - (Incorporated by reference from
                  the Registrant's Registration Statement on Form S-18,
                  File No. 33-10186 LA).

3.2               Amendment to Certificate of Incorporation filed
                  October 29, 1986 - (Incorporated by reference from
                  the Registrant's Registration Statement on Form S-18,
                  File No. 33-10186 LA).

3.3               Amendment to Certificate of Incorporation filed
                  July 12, 1989 - (Incorporated by reference from
                  the Registrant's Annual Report on Form 10-K
                  for the fiscal year ended June 30, 1989.)

3.4               Amendment to Certificate of Incorporation filed
                  August 7, 1990 - (Incorporated by reference from the
                  Registrant's Quarterly Report on Form 10-Q for the
                  Quarter ended September 30, 1990 as amended by
                  a First Amendment on Form 8 filed December 15, 1990.)

3.5               Amendment to Certificate of Incorporation filed
                  May 9, 1991 - (Incorporated by reference from the
                  Registrant's Quarterly Report on Form 10-Q for the
                  quarter ended June 30, 1991.)

3.6               By-Laws of the Company - (Incorporated by reference
                  from the Registrant's Registration Statement on Form S-18,
                  File No. 33-10186 LA).

4                 Instruments Defining the Rights of Security Holders
                  ---------------------------------------------------

4.1               Specimen Stock Certificate - (Incorporated by reference
                  from the Registrant's Registration Statement on Form S-18,
                  File No. 33-10186 LA).
</TABLE>



<PAGE>   36


                            PSYCHEMEDICS CORPORATION

                                      10-K

                                INDEX TO EXHIBITS

<TABLE>
<CAPTION>
Exhibit
Number                              Description
- -------                             -----------

<S>               <C>
10                Material Contracts

10.1              License Agreement  with Werner
                  Baumgartner, Ph.D. and Annette Baumgartner
                  dated January 17, 1987 - (Incorporated by reference
                  from the Registrant's Registration Statement on Form
                  S-18, File No. 33-10186 LA).

10.2*             1989 Employee Stock Option Plan,
                  as amended - (Incorporated by reference from the
                  Registrant's 1997 Annual Proxy Statement.)

10.3*             1989 Non-Qualified Stock Option Plan,
                  as amended (Incorporated by reference from the
                  Registrant's Annual Report on Form 10-K for the
                  fiscal year ended December 31, 1996.

10.4*             1991 Non-Qualified Stock Option Plan -
                  (Incorporated by reference from the Registrant's
                  Annual Report on Form 10-K for the fiscal year
                  ended December 31, 1991.)

10.5              Lease dated October 6, 1992 with Mitchell H.
                  Hersch, et. al with respect to premises in
                  Culver City, California - (Incorporated by reference from
                  the Registrant's Annual Report on Form 10-KSB for
                  for the fiscal year ended December 31, 1992.)

10.5.1            Security Agreement dated October 6, 1992 with Mitchell H.
                  Hersch et. al - (Incorporated by reference from the
                  Registrant's Annual Report on Form 10-KSB for the fiscal year
                  ended December 31, 1992.)

10.5.2            First Amendment to Lease dated with Mitchell H. Hersch, et.al
                  California - (Incorporated by reference from the Registrant's
                  Annual Report on Form 10-K for for the fiscal year ended
                  December 31, 1997.)

10.5.3            Second Amendment to Lease dated with Mitchell H. Hersch,
                  et.al. California - (Incorporated by reference from the
                  Registrant's Annual Report on Form 10-K for for the fiscal
                  year ended December 31, 1997.)

10.5.4            Third Amendment to Lease dated December 31, 1997
                  with Mitchell H. Hersch, et.al. California - (Incorporated by
                  reference from the Registrant's Annual Report on Form 10-K for
                  for the fiscal year ended December 31, 1997.)

10.6*             2000 Employee Stock Option Plan,
                  as amended - (Incorporated by reference from the
                  Registrant's 2000 Annual Proxy Statement.)
</TABLE>


<PAGE>   37


                            PSYCHEMEDICS CORPORATION

                                      10-K

                                INDEX TO EXHIBITS

<TABLE>
<CAPTION>
Exhibit
Number                              Description
- -------                             -----------

<S>               <C>
23                Consents of Experts and Counsel

23.1              Consent of Arthur Andersen LLP                  Filed herewith

27                Financial Data Schedule                         Filed herewith
</TABLE>

                  *Represents a management contract or compensatory plan in
                  which a director or named executive officer of the Registrant
                  participates.



<PAGE>   1

EXHIBIT 23.1


                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS


As independent public accountants, we hereby consent to the incorporation of our
report dated February 8, 2000, included in this Form 10-K, into Psychemedics
Corporation's previously filed Registration Statements File Nos. 33-41787,
33-50712, 33-45332, 33-66942, 33-58970 and 333-12403.



                                                     ARTHUR ANDERSEN LLP

Boston, Massachusetts
March 21, 2000


<TABLE> <S> <C>

<ARTICLE> 5

<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-START>                             JAN-01-1999
<PERIOD-END>                               DEC-31-1999
<CASH>                                         899,387
<SECURITIES>                                 4,938,463
<RECEIVABLES>                                3,219,511
<ALLOWANCES>                                   312,169
<INVENTORY>                                    449,103
<CURRENT-ASSETS>                            10,401,492
<PP&E>                                       8,572,486
<DEPRECIATION>                               5,154,038
<TOTAL-ASSETS>                              14,190,905
<CURRENT-LIABILITIES>                        2,217,458
<BONDS>                                              0
                                0
                                          0
<COMMON>                                       113,062
<OTHER-SE>                                  11,805,927
<TOTAL-LIABILITY-AND-EQUITY>                14,190,905
<SALES>                                     19,622,625
<TOTAL-REVENUES>                            19,622,625
<CGS>                                        8,453,261
<TOTAL-COSTS>                                8,453,261
<OTHER-EXPENSES>                             7,622,493
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                              3,934,564
<INCOME-TAX>                                 1,609,000
<INCOME-CONTINUING>                          2,325,564
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                 2,325,564
<EPS-BASIC>                                       0.11
<EPS-DILUTED>                                     0.11


</TABLE>


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