<PAGE> 1
JOHN HANCOCK GLOBAL RX FUND
CLASS A AND CLASS B SHARES
SUPPLEMENT TO PROSPECTUS DATED JANUARY 1, 1995
ORGANIZATION AND MANAGEMENT OF THE FUND
The fourth paragraph under this heading (on p. 9) is deleted in its
entirety and replaced by:
Day to day management of the Fund is carried out by Michael P.
DiCarlo, supported by an investment team of sector and global
specialists from the Adviser's equity group. Mr. DiCarlo also
manages John Hancock Special Equities Fund, John Hancock Special
Opportunities Fund, and oversees the Adviser's equity management
operation. Mr. DiCarlo is a Senior Vice President of the Adviser
and has been associated with the Adviser since 1984.
July 1, 1995
2800S 7/95
