<PAGE> PAGE 1
000 B000000 10/31/1999
000 C000000 0000807639
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002 A000000 101 HUNTINGTON AVENUE
002 B000000 BOSTON
002 C000000 MA
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002 D020000 7603
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 Y
007 B000000 3
007 C010100 1
007 C010200 2
007 C020200 JOHN HANCOCK PACIFIC BASIN EQUITIES
007 C030200 N
007 C010300 3
007 C020300 JOHN HANCOCK GLOBAL HEALTH SCIENCES FUND
007 C030300 N
007 C010400 4
007 C010500 5
007 C020500 JOHN HANCOCK EUROPEAN EQUITY FUND
007 C030500 N
007 C010600 6
007 C010700 7
007 C010800 8
007 C010900 9
007 C011000 10
011 A00AA01 JOHN HANCOCK FUNDS, INC.
011 B00AA01 8-43582
011 C01AA01 BOSTON
011 C02AA01 MA
011 C03AA01 02199
011 C04AA01 7603
012 A00AA01 JOHN HANCOCK SIGNATURE SERVICES, INC.
012 B00AA01 84-1885
012 C01AA01 BOSTON
012 C02AA01 MA
012 C03AA01 02199
012 C04AA01 7603
<PAGE> PAGE 2
013 A00AA01 PRICEWATERHOUSECOOPERS LLP
013 B01AA01 BOSTON
013 B02AA01 MA
013 B03AA01 02110
015 A00AA01 STATE STREET BANK AND TRUST COMPANY
015 B00AA01 C
015 C01AA01 BOSTON
015 C02AA01 MA
015 C03AA01 02110
015 E01AA01 X
015 A00AA02 ERSTE BANK DER OESTERREICHISCHEN
015 B00AA02 S
015 C01AA02 VIENNA
015 D01AA02 AUSTRIA
015 E04AA02 X
015 A00AA03 FORTIS BANK N.V.
015 B00AA03 S
015 C01AA03 BRUSSELS
015 D01AA03 BELGIUM
015 E04AA03 X
015 A00AA04 STATE STREET TRUST COMPANY CANADA
015 B00AA04 S
015 C01AA04 TORONTO
015 D01AA04 CANADA
015 E04AA04 X
015 A00AA05 DEN DANSKE BANK
015 B00AA05 S
015 C01AA05 COPENHAGEN
015 D01AA05 DENMARK
015 E04AA05 X
015 A00AA06 MERITA BANK LIMITED
015 B00AA06 S
015 C01AA06 HELSINKI
015 D01AA06 FINLAND
015 E04AA06 X
015 A00AA07 BANQUE PARIBAS
015 B00AA07 S
015 C01AA07 PARIS
015 D01AA07 FRANCE
015 E04AA07 X
015 A00AA08 DRESDNER BANK AG
015 B00AA08 S
015 C01AA08 FRANKFURT
015 D01AA08 GERMANY
015 E04AA08 X
015 A00AA09 STANDARD CHARTERED BANK
015 B00AA09 S
015 C01AA09 HONG KONG
015 D01AA09 HONG KONG
015 E04AA09 X
015 A00AA10 BANK OF IRELAND
<PAGE> PAGE 3
015 B00AA10 S
015 C01AA10 DUBLIN
015 D01AA10 IRELAND
015 E04AA10 X
015 A00AA11 CITIBANK, N.A.
015 B00AA11 S
015 C01AA11 QUITO
015 D01AA11 ECUADOR
015 E04AA11 X
015 A00AA12 THE DAIWA BANK, LIMITED
015 B00AA12 S
015 C01AA12 TOKYO
015 D01AA12 JAPAN
015 E04AA12 X
015 A00AA13 WESTPAC BANKING CORPORATION
015 B00AA13 S
015 C01AA13 MELBOURNE
015 D01AA13 AUSTRALIA
015 E04AA13 X
015 A00AA14 STANDARD CHARTERED BANK
015 B00AA14 S
015 C01AA14 KUALA LAMPUR
015 D01AA14 MALAYSIA
015 E04AA14 X
015 A00AA15 CITIBANK MEXICO, S.A.
015 B00AA15 S
015 C01AA15 MEXICO CITY
015 D01AA15 MEXICO
015 E04AA15 X
015 A00AA16 MESSPIERSON N.V.
015 B00AA16 S
015 C01AA16 AMSTERDAM
015 D01AA16 NETHERLANDS
015 E04AA16 X
015 A00AA17 ANZ BANKING GROUP (NEW ZEALAND) LIMITED
015 B00AA17 S
015 C01AA17 WELLINGTON
015 D01AA17 NEW ZEALAND
015 E04AA17 X
015 A00AA18 CHRISTIANIA BANK OG KREDITKASSE
015 B00AA18 S
015 C01AA18 OSLO
015 D01AA18 NORWAY
015 E04AA18 X
015 A00AA19 STANDARD CHARTERED BANK
015 B00AA19 S
015 C01AA19 MANILA
015 D01AA19 PHILIPPINES
015 E04AA19 X
015 A00AA20 BANCO COMERCIAL PORTUGUES
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<PAGE> PAGE 4
015 C01AA20 LISBON
015 D01AA20 PORTUGAL
015 E04AA20 X
015 A00AA21 THE DEVELOPMENT BANK OF SINGAPORE LTD.
015 B00AA21 S
015 C01AA21 SINGAPORE
015 D01AA21 SINGAPORE
015 E04AA21 X
015 A00AA22 BANCO SANTANDER CENTRAL HISPANO, S.A.
015 B00AA22 S
015 C01AA22 MADRID
015 D01AA22 SPAIN
015 E04AA22 X
015 A00AA23 SKANDINAVISKA ENSKILDA BANKEN
015 B00AA23 S
015 C01AA23 STOCKHOLM
015 D01AA23 SWEDEN
015 E04AA23 X
015 A00AA24 UBS AG
015 B00AA24 S
015 C01AA24 ZURICH
015 D01AA24 SWITZERLAND
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015 A00AA25 STANDARD CHARTERED BANK
015 B00AA25 S
015 C01AA25 BANGKOK
015 D01AA25 THAILAND
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015 A00AA26 STATE STREET BANK AND TRUST COMPANY
015 B00AA26 S
015 C01AA26 LONDON
015 D01AA26 UNITED KINGDOM
015 E04AA26 X
015 A00AA27 CITIBANK, N.A.
015 B00AA27 S
015 C01AA27 BUENOS AIRES
015 D01AA27 ARGENTINA
015 E04AA27 X
015 A00AA28 CITIBANK, N.A.
015 B00AA28 S
015 C01AA28 BRASILIA
015 D01AA28 BRAZIL
015 E04AA28 X
015 A00AA29 CITIBANK, N.A.
015 B00AA29 S
015 C01AA29 SANTIAGO
015 D01AA29 CHILE
015 E04AA29 X
015 A00AA30 NATIONAL BANK OF GREECE S.A.
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<PAGE> PAGE 5
015 D01AA30 GREECE
015 E04AA30 X
015 A00AA31 STANDARD CHARTERED BANK
015 B00AA31 S
015 C01AA31 DJAKARTA
015 D01AA31 INDONESIA
015 E04AA31 X
015 A00AA32 THE HONGKONG AND SHANGHAI BANKING CORP. LTD.
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015 C01AA32 PORT LOUIS
015 D01AA32 MAURITIUS
015 E04AA32 X
015 A00AA33 CITIBANK, N.A.
015 B00AA33 S
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015 D01AA33 TURKEY
015 E04AA33 X
015 A00AA34 CITIBANK, N.A.
015 B00AA34 S
015 C01AA34 CARACAS
015 D01AA34 VENEZUELA
015 E04AA34 X
015 A00AA35 THE HONGKONG AND SHANGHAI BANKING
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015 C01AA35 SEOUL
015 D01AA35 REPUBLIC OF KOREA
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015 A00AA36 STANDARD CHARTERED BANK
015 B00AA36 S
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015 D01AA36 BANGLADESH
015 E04AA36 X
015 A00AA37 THE HONGKONG AND SHANGHAI BANKING CORP. LTD.
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015 D01AA37 PEOPLES REP.OF CHINA
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<PAGE> PAGE 6
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015 A00AA42 BANK HAPOALIM B.M.
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015 D01AA43 PAKISTAN
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015 A00AA44 CITIBANK, N.A.
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015 D01AA44 PERU
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015 B00AA45 S
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015 D01AA45 SRI LANKA
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015 A00AA46 BANKBOSTON
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015 C01AA46 MONTEVIDEO
015 D01AA46 URUGUAY
015 E04AA46 X
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015 C01AA47 GARBORNE
015 D01AA47 BOTSWANA
015 E04AA47 X
015 A00AA48 CESKOSLOVENSKA OBCHODNI BANKA, A.S.
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015 D01AA48 CZECH REPUBLIC
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015 A00AA49 BARCLAYS BANK OF GHANA LIMITED
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015 E04AA49 X
015 A00AA50 CESKOSLOVENSKA OBCHODNA BANKA A.S.
015 B00AA50 S
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015 D01AA50 SLOVAK REPUBLIC
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<PAGE> PAGE 7
015 A00AA51 THE BRITISH BANK OF THE MIDDLE EAST
015 B00AA51 S
015 C01AA51 AMMAN
015 D01AA51 JORDAN
015 E04AA51 X
015 A00AA52 BARCLAYS BANK OF KENYA LIMITED
015 B00AA52 S
015 C01AA52 NAIROBI
015 D01AA52 KENYA
015 E04AA52 X
015 A00AA53 BANQUE COMMERCIALE DU MAROC
015 B00AA53 S
015 C01AA53 RABAT
015 D01AA53 MOROCCO
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015 A00AA54 CITIBANK POLAND S.A.
015 B00AA54 S
015 C01AA54 WARSAW
015 D01AA54 POLAND
015 E04AA54 X
015 A00AA55 STANDARD BANK OF SOUTH AFRICA LIMITED
015 B00AA55 S
015 C01AA55 CAPETOWN PRETORIA
015 D01AA55 SOUTH AFRICA
015 E04AA55 X
015 A00AA56 BARCLAYS BANK OF ZAMBIA LIMITED
015 B00AA56 S
015 C01AA56 LUSAKA
015 D01AA56 ZAMBIA
015 E04AA56 X
015 A00AA57 BARCLAYS BANK OF ZIMBABWE LIMITED
015 B00AA57 S
015 C01AA57 HARARE
015 D01AA57 ZIMBABWE
015 E04AA57 X
015 A00AA58 STANDARD BANK SWAZILAND LIMITED
015 B00AA58 S
015 C01AA58 MBABANE
015 D01AA58 SWAZILAND
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015 A00AA59 NATIONAL BANK OF EGYPT
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015 C01AA59 CAIRO
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015 A00AA60 THE BRITISH BANK OF THE MIDLLE EAST
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015 D01AA60 LEBANON
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<PAGE> PAGE 8
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015 C01AA61 TAI PEI
015 D01AA61 TAIWAN - R.O.C.
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015 A00AA67 BRITISH BANK OF THE MIDDLE EAST
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<PAGE> PAGE 9
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015 E04AA72 X
015 A00AA73 ICEBANK LTD
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015 C01AA73 REYKJAVIK
015 D01AA73 ICELAND
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015 D01AA74 INDIA
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015 A00AA75 SCOTIABANK JAMAICA TRUST AND MERCHANT BANK
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015 A00AA78 STANDARD BANK OF SOUTH AFRICA
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015 A00AA80 ING BANK N.V.
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<PAGE> PAGE 10
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<PAGE> PAGE 11
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<PAGE> PAGE 12
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054 F00AA00 N
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054 H00AA00 Y
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<PAGE> PAGE 13
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<PAGE> PAGE 14
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<PAGE> PAGE 15
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<PAGE> PAGE 16
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<PAGE> PAGE 17
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<NAME> JOHN HANCOCK PACIFIC BASIN EQUITIES FUND - CLASS B
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-START> NOV-01-1998
<PERIOD-END> OCT-31-1999
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</TABLE>
<TABLE> <S> <C>
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<SERIES>
<NUMBER> 023
<NAME> JOHN HANCOCK PACIFIC BASIN EQUITIES FUND - CLASS C
<S> <C>
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<PERIOD-START> NOV-01-1998
<PERIOD-END> OCT-31-1999
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</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<SERIES>
<NUMBER> 051
<NAME> JOHN HANCOCK EUROPEAN EQUITY FUND - CLASS A
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-START> NOV-01-1998
<PERIOD-END> OCT-31-1999
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</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<SERIES>
<NUMBER> 052
<NAME> JOHN HANCOCK EUROPEAN EQUITY FUND - CLASS B
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-START> NOV-01-1998
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<INVESTMENTS-AT-COST> 27,855,146
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</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<SERIES>
<NUMBER> 053
<NAME> JOHN HANCOCK EUROPEAN EQUITY FUND - CLASS C
<S> <C>
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<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-START> NOV-01-1998
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<INVESTMENTS-AT-COST> 27,855,146
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</TABLE>
