GENSIA SICOR INC
DEF 14A, 1997-08-13
PHARMACEUTICAL PREPARATIONS
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<PAGE>

                        SCHEDULE 14A INFORMATION
Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant [x]
Filed by a party other than the Registrant [ ]
Check the appropriate box:
[ ] Preliminary Proxy Statement
[ ] Confidential, for Use of the Commission Only (as permitted by 
    Rule 14a-6(e)(2))
[x] Definitive Proxy Statement
[ ] Definitive Additional Materials
[ ] Soliciting Material Pursuant to Section  240.14a-11(c) or 
    Section 240.14a-12

                               GENSIA SICOR INC.
- -------------------------------------------------------------------------------
              (Name of Registrant as Specified In Its Charter)

                                     N/A 
- -------------------------------------------------------------------------------
   (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):
[x] No fee required

[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.
    1)  Title of each class of securities to which transaction applies:

        ----------------------------------------------------------------------

    2)  Aggregate number of securities to which transaction applies:

        ----------------------------------------------------------------------

    3)  Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
        filing fee is calculated and state how it was determined):

        ----------------------------------------------------------------------

    4)  Proposed maximum aggregate value of transaction:

        ----------------------------------------------------------------------

    5)  Total fee paid:

        ----------------------------------------------------------------------
[ ] Fee paid previously with preliminary materials.
[ ] Check box if any part of the fee is offset as provided by Exchange Act Rule
    0-11(a)(2) and identify the filing for which the offsetting fee was paid
    previously.  Identify the previous filing by registration statement number,
    or the Form or Schedule and the date of its filing.
    1)  Amount Previously Paid:

        ----------------------------------------------------------------------

    2)  Form, Schedule or Registration Statement No.:

        ----------------------------------------------------------------------

    3)  Filing Party:

        ----------------------------------------------------------------------

    4)  Date Filed:

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<PAGE>

                         9360 Towne Centre Drive
                           San Diego, CA 92121
                             (619) 546-8300


                             August 12, 1997




Dear Stockholder:

    You are cordially invited to attend the Annual Meeting of Stockholders
which will be held on September 9, 1997, at 11:00 a.m., at the Hyatt Regency
La Jolla, 3777 La Jolla Village Drive, La Jolla, California.

    The formal notice of the Annual Meeting and the Proxy Statement have been
made a part of this invitation.

    After reading the Proxy Statement, please mark, date, sign and return, at
an early date, the enclosed proxy in the prepaid envelope to ensure that your
shares will be represented.  YOUR SHARES CANNOT BE VOTED UNLESS YOU SIGN, DATE
AND RETURN THE ENCLOSED PROXY OR ATTEND THE ANNUAL MEETING IN PERSON.

    A copy of the Company's Annual Report to Stockholders is also enclosed.

    The Board of Directors and Management look forward to seeing you at the
meeting.

                                       Sincerely yours,



                                       David F. Hale
                                       President and Chief Executive Officer

<PAGE>

                            GENSIA SICOR INC.

                              ------------

                NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                      TO BE HELD SEPTEMBER 9, 1997

                              ------------

    The Annual Meeting of Stockholders of Gensia Sicor Inc. (the "Company")
will be held at the Hyatt Regency La Jolla, 3777 La Jolla Village Drive, La
Jolla, California, on September 9, 1997, at 11:00 a.m., for the following
purposes:

    1.   To elect three Class II directors.

    2.   To consider and vote upon a proposal to amend and restate the
         Company's Employee Stock Purchase Plan.

    3.   To consider and vote upon a proposal to amend and restate the
         Company's 1997 Long-Term Incentive Plan.

    4.   To consider and vote upon a proposal to approve the grant to the
         Chairman of the Board of options to purchase up to 500,000 shares of
         Common Stock which were granted in connection with his joining the
         Board.

    5.   To ratify the selection of Ernst & Young LLP as the Company's
         independent auditors.

    6.   To transact such other business as may properly come before the
         Annual Meeting and any adjournment of the Annual Meeting.

    The Board of Directors has fixed the close of business on July 18, 1997, as
the record date for determining the stockholders entitled to notice of and to
vote at the Meeting and any adjournment of the Annual Meeting.  A complete list
of stockholders entitled to vote will be available at the Secretary's office,
9360 Towne Centre Drive, San Diego, California, for ten days before the meeting.

    WHETHER YOU INTEND TO BE PRESENT AT THE ANNUAL MEETING OR NOT, WE URGE YOU
TO MARK, DATE, SIGN AND RETURN THE ENCLOSED PROXY PROMPTLY.


                                       By order of the Board of Directors.



                                       Wesley N. Fach
                                       Secretary

August 12, 1997
<PAGE>

                            GENSIA SICOR INC.
                              ------------

                             PROXY STATEMENT
                              ------------

    This Proxy Statement is furnished in connection with the solicitation by 
the Board of Directors of Gensia Sicor Inc., a Delaware corporation ("Gensia 
Sicor" or the "Company"), with principal executive offices at 9360 Towne 
Centre Drive, San Diego, California 92121, of proxies in the accompanying 
form to be used at the Annual Meeting of Stockholders to be held at the Hyatt 
Regency La Jolla, 3777 La Jolla Village Drive, La Jolla, California, on 
September 9, 1997, and any adjournment of the Annual Meeting (the "Annual 
Meeting").  The shares represented by the proxies received in response to 
this solicitation and not revoked will be voted at the Annual Meeting.  A 
proxy may be revoked at any time before it is exercised by filing with the 
Secretary of the Company a written revocation or a duly executed proxy 
bearing a later date or by voting in person at the Annual Meeting.  On the 
matters coming before the Annual Meeting for which a choice has been 
specified by a stockholder by means of the ballot on the proxy, the shares 
will be voted accordingly.  If no choice is specified, the shares will be 
voted FOR the election of the three nominees for Class II director listed in 
this Proxy Statement and FOR approval of proposals 2, 3, 4 and 5 described in 
the Notice of Annual Meeting and in this Proxy Statement.

    Stockholders of record at the close of business on July 18, 1997 are 
entitled to notice of and to vote at the Annual Meeting.  As of July 31, 1997 
the Company had 74,451,518 shares of Common Stock outstanding and entitled to 
vote.  Each holder of Common Stock is entitled to one vote for each share 
held as of the record date.

    Directors are elected by a plurality vote.  The other matters submitted 
for stockholder approval at the Annual Meeting will be decided by the 
affirmative vote of a majority of shares present in person or represented by 
proxy and entitled to vote on each such matter.  Abstentions with respect to 
any matter are treated as shares present or represented and entitled to vote 
on that matter and thus have the same effect as negative votes.  If shares 
are not voted by the broker who is the record holder of the shares, or if 
shares are not voted in other circumstances in which proxy authority is 
defective or has been withheld with respect to any matter, these non-voted 
shares are not deemed to be present or represented for purposes of 
determining whether stockholder approval of that matter has been obtained.

    The expense of printing and mailing proxy materials will be borne by the 
Company.  In addition to the solicitation of proxies by mail, solicitation 
may be made by certain directors, officers and other employees of the Company 
by personal interview, telephone or telegraph.  No additional compensation 
will be paid to such persons for such solicitation.  The Company will 
reimburse brokerage firms and others for their reasonable expenses in 
forwarding solicitation materials to beneficial owners of the Company's 
Common Stock. Employees of Georgeson & Co., Inc. will also solicit proxies at 
an anticipated fee of approximately $7,500 plus reasonable out-of-pocket 
expenses.

    This Proxy Statement and the accompanying form of proxy are being mailed 
to stockholders on or about August 12, 1997.

                                  IMPORTANT

     WHETHER YOU INTEND TO BE PRESENT AT THE ANNUAL MEETING OR NOT, WE URGE
     YOU TO MARK, DATE AND SIGN THE ENCLOSED PROXY AND RETURN IT AT YOUR
     EARLIEST CONVENIENCE IN THE ENCLOSED POSTAGE-PREPAID RETURN ENVELOPE. 
     THIS WILL NOT LIMIT YOUR RIGHTS TO ATTEND OR VOTE AT THE ANNUAL
     MEETING.

                                      -1-
<PAGE>

                             ELECTION OF DIRECTORS

    The Company has three classes of directors serving staggered three-year 
terms.  Class I and Class II each consist of three directors and Class III 
consists of four directors.  Currently one Class III director's seat is 
vacant. Three Class II directors are to be elected at the Annual Meeting for 
a term of three years expiring at the Annual Meeting in 2000 or until each 
such director's successor shall have been elected and qualified.  The other 
directors of the Company will continue in office for their existing terms, 
which expire in 1998 and 1999 for Class III and Class I directors, 
respectively.

COMPOSITION OF BOARD OF DIRECTORS

    On February 28, 1997, pursuant to a Stock Exchange Agreement, dated as of 
November 12, 1996, as amended on December 16, 1996 (the "Stock Exchange 
Agreement"), between Gensia, Inc. ("Gensia," currently Gensia Sicor) and 
Rakepoll Finance N.V., a corporation organized under the laws of the 
Netherlands Antilles ("Rakepoll Finance"), Gensia acquired all of the 
outstanding shares of capital stock of Rakepoll Holding B.V., a corporation 
organized under the laws of the Netherlands ("Rakepoll Holding") and (prior 
to such acquisition) a wholly-owned subsidiary of Rakepoll Finance, in 
exchange for 29,500,000 shares of common stock, $.01 par value ("Common 
Stock") of the Company and $100,000 in cash (the "Stock Exchange").  See 
"Certain Transactions."  In connection with the Stock Exchange Agreement, 
Gensia and Rakepoll Finance entered into a shareholder's agreement (as 
amended, the "Shareholder's Agreement"), concerning the governance of the 
Company after the acquisition and certain other matters concerning the 
acquisition and disposition of Gensia Sicor securities by Rakepoll Finance 
and its affiliates.  Carlo Salvi, a director of the Company, is the 
controlling beneficial owner of Rakepoll Finance.

    The Shareholder's Agreement specifies that the Company is to have a ten 
member Board of Directors (to be expanded to twelve members in the event that 
holders of Gensia Sicor's Convertible Preferred Stock (other than Rakepoll 
Finance and its affiliates) in accordance with the terms of the Convertible 
Preferred Stock, become entitled to appoint two directors).  The 
Shareholder's Agreement further specifies that the Company shall use its best 
efforts to cause the Gensia Sicor Board of Directors to consist of (i) two 
directors who are executive officers of Gensia Sicor and not affiliated with 
Rakepoll Finance ("Management Directors"), (ii) three directors designated by 
Rakepoll Finance ("Investor Directors") and (iii) five independent directors 
to be designated jointly by the Management Directors and the Investor 
Directors (the "Independent Directors"). David Hale and Patrick Walsh are the 
current Management Directors; Carlo Salvi and Michael Cannon are the current 
Investor Directors; and Donald Panoz, Chairman of the Board, James Blair, 
Herbert Conrad, Carlos Ferrer and L. John Wilkerson are the current 
Independent Directors. The Shareholder's Agreement provides for the third 
Investor Director to be appointed in the future.

    During the term of the Shareholder's Agreement, the number of Investor 
Directors that Rakepoll Finance will be entitled to designate will vary 
according to its ownership interest in Gensia Sicor as a percentage of the 
number of shares of Gensia Sicor Common Stock controlled directly or 
indirectly by Rakepoll Finance and its affiliates immediately following the 
Stock Exchange (the "Initial Interest"). See "Stock Ownership of Management 
and Certain Beneficial Owners." If Rakepoll Finance's ownership interest in 
Gensia Sicor is (i) 50% or above of its Initial Interest, Rakepoll Finance 
shall have the right to designate for nomination and approval three Investor 
Directors; the Management Directors shall have the right to designate for 
nomination and approval two Management Directors; and the five Independent 
Directors shall be designated for nomination and approval jointly by the 
Management Directors and the Investor Directors; (ii) 25% or above but less 
than 50% of its Initial Interest, Rakepoll Finance shall have the right to 
designate for nomination and approval two Investor Directors; and there shall 
be four Independent Directors who shall be designated for nomination and 
approval jointly by the Management Directors and the Investor Directors; 
(iii) 10% or above but less than 25% of its Initial Interest, Rakepoll 
Finance shall have the right to designate for nomination and approval one 
Investor Director; and there shall be three Independent Directors who shall 
be designated for nomination and approval jointly by the Management Directors 
and the Investor Directors. Once Rakepoll Finance's interest has fallen below 
10% of its Initial Interest, Rakepoll Finance shall have no further right to 
designate any Investor

                                      -2-
<PAGE>

Directors or Independent Directors and the Management Directors shall have no 
right to designate any Management Directors or Independent Directors.

    If at any time Rakepoll Finance's ownership interest in Gensia Sicor 
should be reduced with the result that, in accordance with the provisions 
described in the foregoing paragraph, the number of directors which Rakepoll 
Finance is entitled to designate is reduced, then such entitlement reduction 
shall extinguish any right Rakepoll Finance might have under the 
Shareholder's Agreement to designate a greater number of directors, 
notwithstanding any increase in Rakepoll Finance's ownership in Gensia Sicor 
which may occur after such entitlement reduction.

    The Shareholder's Agreement further specifies that vacancies on the 
Gensia Sicor Board of Directors which result from a reduction in Rakepoll 
Finance's and the Management Directors' entitlement to designate directors in 
accordance the terms of the Shareholder's Agreement shall be filled by 
election by the stockholders at large of Gensia Sicor in accordance with 
applicable law, Gensia Sicor's Certificate of Incorporation and its Bylaws.

    Mr. Ferrer was elected, and is nominated for reelection as a Class II 
director pursuant to a securities purchase agreement (the "Purchase 
Agreement") dated May 2, 1997 between the Company and Health Care Capital 
Partners L.P. ("Health Care Capital").  The Purchase Agreement requires the 
Company to nominate for election a designee of Health Care Capital so long as 
Health Care Capital, or its related entities own at least 50% of the 
convertible notes it purchased under the Purchase Agreement or the Preferred 
Stock issuable upon conversion of such notes.  See "Certain Transactions."

    Unless authority to vote for directors is withheld, it is intended that 
the shares represented by the enclosed proxy will be voted for the election 
of Carlos Ferrer, Carlo Salvi and L. John Wilkerson, Ph.D. as Class II 
directors. In accordance with the directions received from Rakepoll Finance, 
the Management Directors and the Investor Directors pursuant to the 
Shareholder's Agreement, the Nominating Committee has nominated Carlo Salvi 
and L. John Wilkerson, Ph.D., currently members of the Board of Directors of 
the Company, as Class II directors.  In accordance with the directions 
received from Health Care Capital, the Management Directors and the Investor 
Directors, the Nominating Committee has nominated Carlos Ferrer, currently a 
member of the Board of Directors of the Company, as a Class II director.  In 
the event any of such nominees becomes unable or unwilling to accept 
nomination or election, the shares represented by the enclosed proxy will be 
voted for the election of the balance of those named and such other person as 
the Board of Directors may select in accordance with the terms of the 
Shareholder's Agreement and the Purchase Agreement.  The Board of Directors 
has no reason to believe that any such nominee will be unable or unwilling to 
serve.

    Set forth below is information regarding the nominees for Class II 
director and the continuing directors of Class III and Class I, including 
information furnished by them as to their principal occupations at present 
and for the past five years, certain directorships held by each, their ages 
as of July 31, 1997, and the year in which each became a director of the 
Company.

Name                                                                      Age
- ----                                                                      ---
CLASS II

Carlos A. Ferrer ........................................................  43

   Mr. Ferrer was elected a director of the Company on May 19, 1997.  He
   has been a member of Ferrer Freeman Thompson & Co. LLC ("FFT"), the
   general partner of Health Care Capital, a private investment fund,
   since July 1995.  From July 1978 until July 1995, Mr. Ferrer was
   employed by CS First Boston Corporation, most recently as 

                                      -3-
<PAGE>

   Managing Director and Head of Global Health Care Investment Banking. 
   Mr. Ferrer is a director of Somatogen, Inc.

Carlo Salvi .............................................................  60

   Mr. Salvi has been a director of the Company and Chairman of the
   Company's executive operating committee since February 1997. 
   Additionally, since February 1997 Mr. Salvi has served as a Chairman
   of the Board of Directors and President of SICOR-Societe Italiana
   Corticosteroidi S.p.A. ("Sicor") of Milan, Italy.  Sicor is a 
   wholly-owned subsidiary of Rakepoll Holding, which is owned by Gensia 
   Sicor. From September 1995 to February 1997 he was a consultant to Alco
   Chemicals Ltd., Swiss Branch ("Alco") in Lugano, Switzerland, which
   acts as an agent and distributor of certain Sicor products.  From 1986
   to September 1995, he was General Manager of Alco.

L. John Wilkerson, Ph.D. ...............................................   54

   Dr. Wilkerson has been a director of the Company since May 1991. 
   Dr. Wilkerson was Chairman of the Board of The Wilkerson Group, a
   healthcare products consulting firm, from 1982 until May 1996 and
   currently he is a consultant to The Wilkerson Group.  Prior to joining
   The Wilkerson Group, Dr. Wilkerson was a Vice President and partner
   responsible for medical supply security analysis and research at Smith
   Barney, Harris, Upham & Co.  Dr. Wilkerson is also a director of
   British Bio-Technology Corporation, plc, and several private
   companies.  He received his doctorate from Cornell University.

CLASS III

James C. Blair, Ph.D. ..................................................   57

   Dr. Blair has been a director of the Company since 1986 and was
   Chairman of the Board of the Company from 1986 to May 1991 and Vice
   Chairman of the Board from May 1991 to March 1997.  He has been a
   General Partner of Domain Associates, a venture capital management
   company, since 1985.  Previously, Dr. Blair was employed in venture
   capital management, investment research and engineering management. 
   Dr. Blair is also a director of Amylin Pharmaceuticals, Inc., Aurora
   Biosciences Corporation, CoCensys, Inc., Dura Pharmaceuticals, Inc.
   ("Dura"), Trega Biosciences, Inc. and Vista Medical Technologies, Inc. 
   He holds a doctoral degree in engineering from the University of
   Pennsylvania.

Herbert J. Conrad ......................................................   64

   Mr. Conrad has been a director of the Company since September 1993. 
   From April 1988 to August 1993, Mr. Conrad was President of the
   Pharmaceuticals Division, and Senior Vice President, of Hoffmann-La
   Roche Inc.  Mr. Conrad was a member of the Board of Directors of
   Hoffmann-La Roche and a member of its Executive Committee from
   December 1981 through August 1993.  Mr. Conrad joined Hoffmann-La
   Roche in 1960 and held various positions over the years including 
   Senior Vice President of the Pharmaceuticals Division, Chairman of the
   Board of Medi-Physics, Inc. and Vice President, Public Affairs and
   Planning Division.  Mr. Conrad is also a director of Biotechnology
   General Corp., and Dura.

                                      -4-
<PAGE>

David F. Hale............................................................  48

   Mr. Hale has been President and Chief Executive Officer of the Company
   since June 1987 and was Chairman of the Board of Directors from May
   1991 to February 1997.  Prior to joining Gensia, Mr. Hale was
   President and Chief Executive Officer of Hybritech Incorporated, a
   biotechnology company which was acquired by Eli Lilly & Company in
   1986.  Mr. Hale joined Hybritech in 1982 as Senior Vice President of
   Marketing and Business Development, became Executive Vice President
   and Chief Operating Officer later that year, President in 1983 and
   Chief Executive Officer in 1986.  Before joining Hybritech, Mr. Hale
   was Vice President and General Manager of BBL Microbiology Systems, a
   division of Becton, Dickinson and Company.  Earlier in his career, he
   held several positions at Ortho Pharmaceutical Corporation, a division
   of Johnson & Johnson, including Director of the Ortho Dermatological
   Division and Director of Product Management.  Mr. Hale serves on the
   boards of Dura and Sequana Therapeutics, Inc.

CLASS I

Donald E. Panoz ........................................................   62

   Mr. Panoz has been Chairman of the Board of Directors of the Company 
   since February 1997.  Mr. Panoz was a founder and principal 
   shareholder of Elan Corporation, plc ("Elan") and was Chairman of the 
   Board from 1970 to December 1996.  Until January 1995, he held the 
   position of Chief Executive Officer of Elan.  Mr. Panoz was a founder 
   of Mylan Laboratories and served as its President from 1960 to 1969.  
   Mr. Panoz is executive chairman of Fountainhead Holdings Ltd. (an 
   investment holding company) and of Fountainhead Development Corp., 
   Inc.,  its principal U.S. operating subsidiary.  He also serves as 
   non-executive chairman of Warner Chilcott, plc (formerly Nale 
   Laboratories, plc).  Mr. Panoz continues to serve on the board of 
   Elan.

Michael D. Cannon ......................................................   52

   Mr. Cannon has been a director of the Company and Executive Vice 
   President of the Company since February 1997.  Mr. Cannon has been 
   employed by Sicor since its founding in 1983 and has served as a 
   member of the Board of Directors of Sicor since 1994.  From 1986 to 
   1997 he was Director of Business Development of Alco.  Mr. Cannon 
   worked in a variety of technical positions at SIRS S.p.A., a 
   manufacturer of bulk corticosteroids in Milan, Italy from 1970 to 1982.

Patrick D. Walsh .......................................................   36

   Mr. Walsh has been a director of the Company since February 1997 and 
   has been President and Chief Operating Officer of Gensia Laboratories, 
   Ltd. ("Gensia Laboratories") since November 1995.  From July 1994 to 
   November 1995, he was Executive Vice President and Chief Operating 
   Officer of Gensia Laboratories.  He was Vice President of Sales and 
   Marketing for Fujisawa U.S.A. from 1991 to 1994.  From 1984 to 1991 
   he held various sales and marketing positions at Fujisawa U.S.A.

    The Board of Directors held 14 meetings during the 1996 fiscal year.  All 
Directors then in office attended at least 75% of the aggregate number of 
meetings of the Board and of the Committees on which such Directors serve 
except for Directors Blair and Wilkerson who attended less than 75% of such 
meetings.

    The Board of Directors has appointed a Stock Option Committee, a
Compensation Committee, an Audit Committee, an Executive Committee and a
Nominating Committee.

                                      -5-
<PAGE>

    The current members of the Stock Option Committee are James Blair and 
Herbert Conrad.  The Stock Option Committee held three meetings during the 
1996 fiscal year.  The Stock Option Committee's function is to administer the 
Gensia, Inc. Amended and Restated 1990 Stock Plan (the "1990 Stock Plan") and 
the Gensia Sicor Inc. 1997 Long-Term Incentive Plan (the "1997 Stock Plan").  
See "Report to Stockholders on Executive Compensation."

    The current members of the Compensation Committee are James Blair, 
Herbert Conrad and Carlo Salvi.  The Compensation Committee held four 
meetings during the 1996 fiscal year.  The Compensation Committee's functions 
are to determine and supervise compensation to be paid to officers and 
directors of the Company. See "Report to Stockholders on Executive 
Compensation."

    The current members of the Audit Committee are James Blair, Michael 
Cannon and Herbert Conrad.  The Audit Committee held two meetings during the 
1996 fiscal year.  The Audit Committee's functions are to monitor the 
effectiveness of the audit effort, to supervise the Company's financial and 
accounting organization and financial reporting and to select a firm of 
certified public accountants whose duty it is to audit the books and accounts 
of the Company for the fiscal year for which they are appointed.

    The current members of the Executive Committee are James Blair, David 
Hale, Carlos Ferrer, Donald Panoz, Carlo Salvi and L. John Wilkerson.  The 
Executive Committee held no meeting during the 1996 fiscal year.  The 
Executive Committee has been delegated the right to exercise all the power 
and authority of the Board of Directors to the extent permitted by Delaware 
law and the Company's Charter.

    The members of the Nominating Committee are David Hale, Carlo Salvi and 
L. John Wilkerson.  The Nominating Committee held one meeting during the 1996 
fiscal year.  The Nominating Committee's function is to select and nominate 
individuals to fill vacancies in the Company's Board of Directors.  The 
Nominating Committee will not consider nominees recommended by security 
holders.

                  THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR 
                  THE CLASS II DIRECTOR NOMINEES LISTED ABOVE.

                                      -6-
<PAGE>

        STOCK OWNERSHIP OF MANAGEMENT AND CERTAIN BENEFICIAL OWNERS

    The following table sets forth information as of July 31, 1997, as to 
shares of Common Stock beneficially owned by (i) each director and nominee 
for director, (ii) the officers of the Company named in the Summary 
Compensation Table set forth herein, (iii) the directors and executive 
officers of the Company as a group and (iv) each person known by the Company 
to be the beneficial owner of more than 5% of the outstanding shares of 
Common Stock of the Company.  Except as otherwise indicated and subject to 
applicable community property laws, each person has sole investment and 
voting power with respect to the shares shown.  Ownership information is 
based upon information furnished by the respective individuals or entities, 
as the case may be.

                                                      BENEFICIAL OWNERSHIP
                                                         OF COMMON STOCK 
                                                  ----------------------------
                                                   NUMBER OF        PERCENT
                                                   SHARES(1)       OF CLASS(2)
                                                  -------------    -----------
Rakepoll Finance N.V...........................   29,500,000          39.6%
  Caracas baaiweg 201
  P.O. Box 6085
  Curacao, Netherlands Antilles
James C. Blair ................................      126,568(3)           *
Michael D. Cannon..............................            0              *
Herbert J. Conrad..............................       33,361(4)           *
Carlos A. Ferrer ..............................    6,613,756(5)        8.2%
David F. Hale. ................................    1,061,767(6)        1.4%
Donald E. Panoz................................      650,000(7)           *
Carlo Salvi. . ................................   30,090,000(8)       40.4%
Patrick  D. Walsh..............................       62,759(9)           *
L. John Wilkerson..............................       79,673(10)          *
Daniel D. Burgess..............................      127,297(11)          *
Paul K. Laikind................................      413,177(12)          *
Gene F. Tutwiler ..............................       57,820(13)          *
All directors and executive officers
   as a group (16 persons) ....................   39,231,935(14)      47.6%

- -------------
*Less than one percent

(1)  To the Company's knowledge, the persons named in the table have sole voting
     and investment power with respect to all shares of Common Stock shown as
     beneficially owned by them, subject to community property laws where
     applicable and the information contained in the footnotes to this table.

(2)  For purposes of computing the percentage of outstanding shares held by each
     person or group of persons named above on a given date, shares which such
     person or group has the right to acquire within 60 days after such date are
     deemed to be outstanding, but are not deemed to be outstanding for the
     purposes of computing the percentage ownership of any other person.

(3)  Includes 14,750 shares which Dr. Blair has the right to acquire within 60
     days of July 31, 1997 pursuant to the exercise of options and warrants. 
     Dr. Blair is a General Partner of One Palmer Square Associates, L.P., the
     general partner of Domain Partners, L.P.  Includes 50,000 shares which
     Domain Partners III, L.P. has the right to acquire within 60 days of July
     31, 1997.  Dr. Blair is a General Partner of One Palmer Square Associates
     III, L.P., the general partner of Domain Partners III, L.P.  Dr. Blair has
     an indirect beneficial interest in these shares.  Includes 1,509 shares
     beneficially owned by Domain Associates Profit Sharing Plan.  Includes
     4,125 shares which Domain Associates has the right to acquire within
     60 days of July 31, 1997 pursuant to the exercise of warrants.  Dr. Blair
     is a General Partner of Domain Associates.

(4)  Includes 33,361 shares which Mr. Conrad has the right to acquire within
     60 days of July 31, 1997 pursuant to the exercise of options.

(5)  Includes 6,613,756 shares which may be acquired within 60 days of July 31,
     1997 pursuant to the conversion of convertible notes and exercise of
     warrants owned by Health Care Capital, the general partner of which is 
     FFT. Mr. Ferrer is a member of FFT.  Mr. Ferrer disclaims beneficial 
     ownership of the notes and warrants held by Health Care Capital.

                                      -7-
<PAGE>

(6)  Includes 448,000 shares held by a trust as to which Mr. Hale has shared
     voting and investment power, 54,000 shares held by Mr. Hale as custodian
     for his minor children as to which Mr. Hale has sole voting and investment
     power, and 423,036 shares which Mr. Hale has the right to acquire within 60
     days of July 31, 1997 pursuant to the exercise of options and warrants.

(7)  Includes 200,000 shares Mr. Panoz has the right to acquire within 60 days
     of July 31, 1997 pursuant to the exercise of options.  Includes 300,000
     shares which Mr. Panoz may have the right to acquire within 60 days of July
     31, 1997 pursuant to the exercise of options that vest upon the attainment
     of certain corporate objectives.

(8)  Includes 29,500,000 shares owned by Rakepoll Finance, a majority-owned
     direct subsidiary of Korbona Industries Ltd., which is wholly-owned by
     Mr. Salvi.  Also includes 440,000 shares owned by Nora Real Estate a.A. and
     50,000 shares owned by Alco, both of which are wholly-owned by Mr. Salvi.

(9)  Includes 61,359 shares which Mr. Walsh has the right to acquire within
     60 days of July 31, 1997 pursuant to the exercise of options.

(10) Includes 2,062 shares which Dr. Wilkerson has the right to acquire within
     60 days of July 31, 1997 pursuant to the exercise of warrants.  Includes
     16,111 shares which Dr. Wilkerson has the right to acquire within 60 days
     of July 31, 1997 pursuant to the exercise of options.  Includes 41,250
     shares owned by Longbow Partners and 20,250 shares which Longbow Partners
     has the right to acquire within 60 days of July 31, 1997 pursuant to the
     exercise of options.  Longbow Partners is a partnership of which the
     partners are certain shareholders of The Wilkerson Group.  Dr. Wilkerson
     disclaims beneficial ownership of the shares and options held by Longbow
     Partners.  Dr. Wilkerson is a consultant to The Wilkerson Group.

(11) Includes 82,908 shares which Mr. Burgess has the right to acquire within 60
     days of July 31, 1997 pursuant to the exercise of options.

(12) Includes 76,636 shares which Dr. Laikind has the right to acquire within 60
     days of July 31, 1997 pursuant to the exercise of options.

(13) Includes 41,636 shares which Dr. Tutwiler has the right to acquire within
     60 days of July 31, 1997 pursuant to the exercise of options.

(14) Includes 7,939,990 shares which may be acquired within 60 days of July 31,
     1997 pursuant to the exercise of options and warrants.  Includes 562,000
     shares held by trusts for the benefit of family members of directors and
     officers as to which such directors and officers have voting and investment
     power.

                                      -8-
<PAGE>

               COMPENSATION OF EXECUTIVE OFFICERS AND DIRECTORS

   Information is set forth below concerning the annual and long-term 
compensation for services in all capacities to the Company for the fiscal 
years ended December 31, 1994, 1995, and 1996, of those persons who were at 
December 31, 1996 (i) the Chief Executive Officer and (ii) the other four 
most highly compensated executive officers of the Company whose salary and 
bonus exceeded $100,000 (the "Named Executive Officers").  Mr. Hale's base 
salary for 1997 has been set at the same level as his 1996, 1995 and 1994 
base salaries. Mr. Burgess resigned as Vice President, Finance, Chief 
Financial Office and Treasurer effective February 26, 1997 in connection with 
his appointment as President of Gensia Automedics Inc.  In connection with 
the Stock Exchange and to permit the appointment of Donald E. Panoz as 
Non-Executive Chairman of the Board, Mr. Hale resigned as Chairman of the 
Board effective February 28, 1997.

<TABLE>
<CAPTION>
                       SUMMARY COMPENSATION TABLE

                                              ANNUAL COMPENSATION                 LONG TERM COMPENSATION 
                                 ------------------------------------------  --------------------------------
                                                                                           AWARDS
                                                                             --------------------------------
                                                                                                  SECURITIES    ALL OTHER
NAME AND PRINCIPAL                                           OTHER ANNUAL     RESTRICTED STOCK    UNDERLYING     COMPEN-
    POSITION              YEAR   SALARY ($)    BONUS ($)   COMPENSATION ($)      AWARDS ($)       OPTIONS (#)   SATION ($)
- ----------------------    ----   ----------    ---------   ----------------   ----------------    -----------   -----------
<S>                       <C>    <C>           <C>         <C>                <C>                 <C>           <C>
David F. Hale             1996   $450,000         -               -                  -                -          $20,300(2)
President, Chief          1995   $450,000      $50,800            -              $149,625(1)        75,000       $19,200(2)
Executive Officer         1994   $450,000         -               -                  -             200,000(3)    $14,100(2)
and Chairman of the 
Board 

Patrick D. Walsh          1996   $208,000         -            $60,100(4)            -                -          $ 2,800(5) 
President and Chief       1995   $185,000      $35,800         $53,500(4)        $ 59,850(1)        25,000       $ 1,500(5)
Operating Officer of      1994   $ 89,400         -            $65,500(4)        $ 72,975(6)        65,000(7)    $   300(5)
Gensia Laboratories 

Daniel D. Burgess         1996   $175,000         -               -                  -                 -         $22,600(8)
Vice President,           1995   $160,000      $40,800            -              $ 59,850(1)        15,000       $22,400(8)
Finance, Chief            1994   $152,500         -               -              $ 72,975(6)        65,000(9)    $ 2,300(8)
Financial Officer 
and Treasurer

Paul K. Laikind, Ph.D     1996   $160,000         -            $ 3,000              -                  -         $ 3,500(10)
Vice President,           1995   $145,000      $25,800         $ 3,000           $ 59,850(1)        15,000       $ 3,400(10)
Corporate Development     1994   $145,000         -            $ 3,000           $ 72,975(6)        65,000(11)   $ 3,100(10)

Gene F. Tutwiler, Ph.D    1996   $ 95,700(12)  $40,000         $99,020(13)       $75,795(14)        40,000       $ 2,900(15)
Executive Vice President, 
Research and Development  
</TABLE>

(1)  Represents the aggregate of the fair market value of the shares of
     restricted stock as of the date of grant ($4.00 per share) less the
     aggregate consideration paid therefor ($.01 per share).  In December 1995,
     the Company's Board of Directors determined that in order to encourage its
     employees, including officers, to continue to play a key role in building
     long-term value at the Company, it should provide such employees with a
     restricted stock award as an incentive to stay at the Company and assist in
     creating this value.  The Board of Directors then authorized certain
     employees, including officers, the opportunity to exchange certain of their
     outstanding stock options for restricted stock awards.  In addition, each
     such employee who elected to exchange his or her options was granted
     additional restricted stock awards for a number of shares equal to two
     times the number of shares which had been exchanged.  Accordingly,
     Messrs. Hale, Burgess, Laikind and Walsh each had the right to purchase
     restricted shares of Common Stock of the Company for a nominal cash
     purchase price equal to the par value of the stock ($.01 per share) in
     exchange for certain options held by each.  The restricted shares vested in
     full on January 31, 1997.  Mr. Hale received an award of 37,500 shares of
     restricted stock and each of Messrs. Burgess, Laikind, and Walsh received
     an award of 15,000 shares of restricted stock.  The aggregate number and
     value of all restricted shares held by Mr. Hale at December 31, 1996 were
     37,500 and $173,100, respectively.  The aggregate number and value of all
     restricted shares held by each of Messrs. Burgess, Laikind and Walsh at
     December 31, 1996 were 45,000 and $207,675 respectively.

                                      -9-
<PAGE>

(2)  Represents $9,100, $14,700, and $15,800, the respective amounts paid by the
     Company for long-term disability insurance premiums for Mr. Hale in 1994,
     1995, and 1996, and $5,000, $4,500, and $4,500, the respective amounts paid
     by the Company for life insurance premiums for Mr. Hale in 1994, 1995, and
     1996.

(3)  Includes options to purchase 150,000 shares of the Company's Common Stock
     at exercise prices greater than $4.875 which were canceled in October 1994
     in exchange for an option to purchase 150,000 shares of the Company's
     Common Stock at an exercise price of $4.875 per share, the fair market
     value on the date of grant.

(4)  Represents $65,500, $53,500 and $60,100, the respective amounts paid by the
     Company to Mr. Walsh for expenses in connection with his relocation to San
     Diego in 1994, 1995 and 1996, and includes payments to Mr. Walsh for taxes
     he incurred on certain relocation expenses.  The respective amounts of
     relocation reimbursement and tax reimbursement for 1994 are $45,500 and
     $20,000.  The respective amounts of relocation reimbursement and tax
     reimbursement for 1995 are $32,500 and $21,000.

(5)  Represents $1,000 and $2,000 paid by the Company for long-term disability
     insurance premiums for Mr. Walsh in 1995 and 1996 and $300, $500 and $800,
     the respective amounts paid by the Company for certain life insurance
     premiums for Mr. Walsh in 1994, 1995, and 1996.

(6)  Represents the aggregate of the fair market value of the shares of
     restricted stock as of the date of grant ($4.875 per share) less the
     aggregate consideration paid therefor ($.01 per share).  As of October 29,
     1994, officers and certain employees were given the opportunity to exchange
     certain of their outstanding stock options for restricted stock awards. 
     Accordingly, Messrs. Walsh, Laikind and Burgess each had the right to
     purchase restricted shares of Common Stock of the Company for a nominal
     cash purchase price equal to the par value of the stock ($.01 per share) in
     exchange for certain options held by each.  The restricted shares vested in
     full on March 31, 1996. Each of Messrs. Walsh, Laikind and Burgess received
     an award of 15,000 shares of restricted stock.

(7)  Includes options to purchase 25,000 shares of the Company's Common Stock at
     exercise prices greater than $4.875 which were canceled in October 1994 in
     exchange for an option to purchase 25,000 shares of the Company's Common
     Stock at an exercise price of $4.875 per share, the fair market value on
     the date of grant.

(8)  Represents $1,900, $1,900 and $2,000, the respective amounts paid by the
     Company for long-term disability insurance premiums for Mr. Burgess in
     1994, 1995 and 1996, and $400, $500, and $600, the respective amounts paid
     by the Company for certain life insurance premiums for Mr. Burgess in 1994,
     1995 and 1996.  For 1995 and 1996, also represents certain indebtedness of
     Mr. Burgess forgiven by the Company in the amount of $20,000 each year.

(9)  Includes options to purchase 30,000 shares of the Company's Common Stock at
     exercise prices greater than $4.875 which were canceled in October 1994 in
     exchange for an option to purchase 30,000 shares of the Company's Common
     Stock at an exercise price of $4.875 per share, the fair market value on
     the date of grant.

(10) Represents $2,600, $2,600 and $2,700, the respective amounts paid by the
     Company for long-term disability insurance premiums for Dr. Laikind in
     1994, 1995 and 1996, and $500, $800, and $900, the respective amounts paid
     by the Company for certain life insurance premiums for Dr. Laikind in 1994,
     1995 and 1996.

(11) Includes options to purchase 25,000 shares of the Company's Common Stock at
     exercise prices greater than $4.875 which were canceled in October 1994 in
     exchange for an option to purchase 25,000 shares of the Company's Common
     Stock at an exercise price of $4.875 per share, the fair market value on
     the date of grant.

(12) Dr. Tutwiler joined the Company in June 1996 and his salary reflects a
     partial year of employment.

(13) Represents $64,000 paid by the Company to Dr. Tutwiler for expenses in
     connection with his relocation to San Diego in 1996 and $35,100 in taxes he
     incurred on certain relocation expenses.

(14) Represents the aggregate of the fair market value of the shares of
     restricted stock as of the date of grant ($5.063 per share) less the
     aggregate consideration paid therefor ($.01 per share).  On June 25, 1996,
     the Company's Board of Directors authorized an award of 15,000 shares of
     restricted stock to Dr. Tutwiler.  The restricted shares vested in full on
     February 28, 1997 due to a change in control of the Company.  The aggregate
     number and value of all restricted shares held by Dr. Tutwiler at
     December 31, 1996 were $15,000 and $69,225, respectively.

(15) Represents $1,400, the amount paid by the Company for long-term disability
     insurance premiums for Dr. Tutwiler in 1996, and $1,500, the amount paid by
     the Company for certain life insurance premiums for Dr. Tutwiler in 1996.


COMPENSATION OF DIRECTORS

   The members of the Board of Directors who are not employees of the Company
(other than Mr. Panoz and Mr. Salvi) receive an annual retainer of $10,000 and
they are reimbursed for reasonable expenses incurred

                                      -10-
<PAGE>

in connection with meetings of the Board of Directors and its committees.  In 
addition, continuing non-employee directors (other than Mr. Panoz and Mr. 
Salvi) receive automatic grants of options to purchase 7,500 shares of the 
Company's Common Stock at the conclusion of each annual meeting of 
stockholders.  On April 28, 1997, the non-employee directors:  Drs. Blair and 
Wilkerson, Mr. Conrad and Jerry C. Benjamin, who subsequently resigned in May 
1997 to permit the appointment of Carlos A. Ferrer in accordance with the 
Purchase Agreement, received a one-time grant of options to purchase 25,000 
shares of the Company's Common Stock.  New non-employee directors will 
receive a similar one-time grant of options to purchase 25,000 shares of the 
Company's Common Stock.  Mr. Ferrer received this one-time grant in 
connection with his joining the Board of Directors in May 1997.

   Effective February 26, 1997, the 1990 Stock Plan was amended to (i) 
accelerate all unvested options granted to non-employee directors under the 
formula grant section of the 1990 Stock Plan, (ii) permit such options to 
continue to be exercisable during the full term of such options in the event 
of termination of service, provided that such director agrees to hold any 
Common Stock acquired upon exercise of such options for a minimum of six 
months from the date of termination, and (iii) to extend the total term of 
such options from seven years to ten years.  Two non-employee directors who 
received formula grants of options under the 1990 Stock Plan have 
subsequently resigned: Mr. Benjamin and Steven C. Mendell who resigned in 
order to permit the required appointment of directors pursuant to the 
Shareholders Agreement.

   In connection with Donald Panoz agreeing to act as the non-executive 
Chairman of the Board of the Company and to provide certain other services to 
the Company, the Company agreed to pay an annual fee of $200,000 for two 
years and granted Mr. Panoz options to purchase 500,000 shares of the 
Company's Common Stock at an exercise price of $4.288 per share.  See 
Proposal 4 "Approval of the Chairman's Options."  Of these options, 200,000 
shares are fully vested, and the remaining 300,000 shares will vest in 
increments of 100,000 shares for each $100,000,000 increase in the Company's 
market capitalization, prior to February 28, 2000, over $700,000,000.  The 
agreement may be terminated by either party on 30 days' advance notice in 
writing, however if the Company terminates, it will pay Mr. Panoz the 
difference between $200,000 and any amounts previously paid.  In addition, if 
Mr. Panoz' agreement  is not earlier terminated and the Company's market 
capitalization, prior to February 28, 2000, exceeds $1,000,000,000, Mr. Panoz 
will be paid a bonus of $1,000,000, payable in equal annual installments over 
a ten-year period, in cash or, at the option of the Company, in stock of the 
Company.

   Carlo Salvi, as Chairman of the Board of Sicor is entitled to receive 
100,000,000 Italian Lira  (approximately $59,000) per year.  Michael Cannon, 
as a member of the Sicor Board of Directors, is entitled to receive 
15,000,000 Italian Lira (approximately $8,850) per year.

SEVERANCE AGREEMENTS

   The Company is a party to certain Severance Agreements (the "Severance 
Agreements") with the Chief Executive Officer and each of the Named Executive 
Officers and certain other officers and key employees.  Pursuant to the 
Severance Agreements, (i) if, within the first 12-month period after the 
occurrence of a "Change in Control" of the Company, (a) the officer 
voluntarily resigns for "Good Reason" or (b) the Company terminates the 
officer's employment for any reason other than "Cause" or "Disability," or 
(ii) if the Company terminates the officer's employment because his position 
has been eliminated in connection with a restructuring or reduction in force, 
as determined by the Company, the officer will be entitled to receive a 
severance payment during the "Continuation Period" at an annual rate equal to 
the sum of (i) the employee's base compensation at the annual rate in effect 
on the date when the termination of his employment with the Company is 
effective plus (ii) the arithmetic mean of the employee's annual bonuses for 
the last three calendar years completed prior to the date when the 
termination of his employment with the Company is effective.  Further, the 
Continuation Period is treated as employment for purposes of determining the 
employee's vesting in any stock options and shares of restricted stock 
granted to him by the Company.

                                      -11-
<PAGE>

   The "Continuation Period" is defined (except with respect to Mr. Hale's 
Severance Agreement) as the period commencing on the effective date of the 
employee's termination of employment and ending on the earlier of (i) the 
date nine months after the date when the employment termination was effective 
or (ii) the date of the employee's death.  If, however, the employee is not 
employed in a new position comparable to his position with the Company on the 
date nine months after his employment termination was effective, then the 
Continuation Period is extended to the date when the employee becomes 
employed in such a position, but in no event by more than three months.  With 
respect to Mr. Hale only, the Continuation Period is defined as the period 
commencing on the effective date of Mr. Hale's termination of employment and 
ending on the earlier of (i) 18 months after the date when the employment 
termination was effective or (ii) the date of Mr. Hale's death.

   "Change in Control" is defined as the occurrence of any of the following 
events:  (i) the first purchase of shares of the Company's Common Stock 
pursuant to a tender offer or exchange offer (other than an offer by the 
Company) for all, or any part, of such Common Stock; (ii) any acquisition of 
voting securities of the Company by any person or group, which theretofore 
did not beneficially own voting securities, representing more than 30% of the 
voting power of all outstanding voting securities of the Company, if such 
acquisition results in such entity, person or group owning beneficially 
securities representing more then 30% of the voting power of all outstanding 
voting securities of the Company; (iii) approval by the Company's 
stockholders of a merger in which the Company does not survive as an 
independent publicly-owned corporation, a consolidation, or a sale, exchange 
or other disposition of all, or substantially all, of the Company's assets; 
or (iv) a change in the composition of the Company's Board of Directors 
during any period of two consecutive years such that individuals who at the 
beginning of such period were members of the Board cease for any reason to 
constitute at least a majority thereof, unless the election, or the 
nomination for election by the Company's stockholders, of each new Director 
was approved by a vote of at least two-thirds of the Directors then still in 
office who were Directors at the beginning of the period.

   "Good Reason" means that the employee:  (i) has been demoted or has 
incurred a material reduction in his authority or responsibility as an 
employee of the Company; (ii) has incurred a reduction in his total 
compensation (including benefits) as an employee of the Company; (iii) has 
not received a contemporaneous increase in his total compensation (including 
benefits) which is commensurate with increases in total compensation 
(including benefits) received by a majority of executive-level employees of 
the Company with duties and responsibilities substantially comparable to 
those of the employee; (iv) has not received a bonus commensurate with 
bonuses (if any) received by a majority of executive-level employees of the 
Company with duties and responsibilities substantially comparable to those of 
the employee; or (v) has been notified that his principal place of work as an 
employee of the Company will be relocated by a distance of 50 miles or more.

   "Cause" means (i) a willful act by the employee which constitutes 
misconduct or fraud and which is injurious to the Company or (ii) conviction 
of, or a plea of "guilty" or "no contest" to, a felony.

STOCK OPTIONS

   The following tables summarize option grants and exercises during fiscal 
1996 to or by the Chief Executive Officer and the Named Executive Officers, 
and the value of the options held by such persons at the end of fiscal 1996.  
The Company does not grant Stock Appreciation Rights.

                                      -12-
<PAGE>


                           OPTION GRANTS IN FISCAL 1996

<TABLE>
<CAPTION>
                                                                                   POTENTIAL REALIZABLE
                                                                                     VALUE AT ASSUMED
                                                                                      ANNUAL RATES OF
                                                                                    STOCK APPRECIATION
                                   INDIVIDUAL GRANTS(1)                             FOR OPTION TERM(2)
                  ------------------------------------------------------------   ------------------------
                   NUMBER OF      % OF TOTAL
                  SECURITIES    OPTIONS GRANTED
                  UNDERLYING          TO            EXERCISE
                    OPTIONS      EMPLOYEES IN        OR BASE       EXPIRATION
NAME              GRANTED (#)   FISCAL YEAR 1996    PRICE ($/SH)      DATE          5% ($)      10% ($)
- ----              -----------   ----------------    ------------   -----------   ----------   ----------
<S>               <C>           <C>                 <C>            <C>           <C>           <C>
David F. Hale,         -              -                 -               -            -             - 
Chief Executive
Officer

Patrick D. Walsh       -              -                 -               -            -             - 

Daniel D. Burgess      -              -                 -               -            -             - 

Paul K. Laikind        -              -                 -               -            -             - 

Gene F. Tutwiler     40,000          4.7%             $5.063         6/28/06     $127,364      $322,765

</TABLE>

- --------------
(1)  Generally, options become exercisable ratably on a daily basis over a 
     four-year period and vest in full in the event of a change in control 
     with respect to the Company and in the event of the death of the 
     optionee.  As a result of the Stock Exchange, all options automatically 
     vested on February 28, 1997.  The exercise price per share of options 
     granted in 1995 represented the fair market value of the underlying 
     shares on the date of grant.  Generally, options granted have a term of 
     10 years, subject to earlier termination in certain events related to 
     termination of employment.

(2)  The 5% and 10% assumed rates of appreciation are mandated by the rules 
     of the Securities and Exchange Commission and do not represent the 
     Company's estimate or projection of the future Common Stock price.

         AGGREGATED OPTION EXERCISES IN FISCAL 1996 AND VALUE OF OPTIONS
                            AT END OF FISCAL 1996

<TABLE>
<CAPTION>
                                                                     NUMBER OF SECURITIES        VALUE OF UNEXERCISED
                                                                    UNDERLYING UNEXERCISED           IN-THE-MONEY
                                                                       OPTIONS AT END OF           OPTIONS AT END OF
                                                                        FISCAL 1996 (#)           FISCAL 1996 ($)(1)
                             SHARES ACQUIRED       VALUE          -------------------------    -------------------------
NAME                         ON EXERCISE (#)     REALIZED ($)     EXERCISABLE/UNEXERCISABLE    EXERCISABLE/UNEXERCISABLE
- ----                         ---------------     ------------     -------------------------    -------------------------
<S>                          <C>                 <C>              <C>                          <C>
David F. Hale,                       -               -                 378,523/68,977              $278,379/$43,471 
Chief Executive
Officer

Patrick D. Walsh                     -               -                 19,169/25,831                $2,812/$7,938

Daniel D. Burgess                    -               -                 60,036/22,464               $20,709/$7,011

Paul K. Laikind                      -               -                 63,815/18,685               $32,889/$7,011

Gene F. Tutwiler                     -               -                      0/40,000                    $0/$0
</TABLE>

(1)  Calculated on the basis of the fair market value of the underlying 
     securities at December 31, 1996 ($4.63), minus the exercise price.

                                      -13-
<PAGE>


             REPORT TO STOCKHOLDERS ON EXECUTIVE COMPENSATION

   The Compensation Committee of the Board of Directors of the Company (the 
"Committee") and the Stock Option Committee are pleased to present their 
report on executive compensation.  This report is provided by the Committee 
to assist stockholders in understanding the Committee's objectives and 
procedures in establishing the compensation of the Company's executive 
officers and describes the basis on which compensation determinations for 
1996 were made by the Committee.  In making its determinations, the Committee 
has relied, in part, on geographic and competitive considerations,  
independent surveys of compensation of management of companies in the 
biotechnology and pharmaceutical industries, including companies included in 
the Nasdaq Pharmaceutical Stock Index used in the Company's Stock Price 
Performance Graph set forth in this proxy statement, and recommendations of 
management.

COMPENSATION PHILOSOPHY AND OBJECTIVES

   The Committee believes that compensation of the Company's executive 
officers should:

   -    Encourage creation of stockholder value and achievement of strategic
        corporate objectives.

   -    Integrate compensation with the Company's annual and long-term
        corporate objectives and strategy, and focus executive behavior on the
        fulfillment of those objectives.

   -    Recognize individual initiative, effort and accomplishment.

   -    Provide a competitive total compensation package that enables the
        Company to attract and retain, on a long-term basis, high caliber
        personnel.

   -    Provide a total compensation opportunity that is competitive with
        companies in the biotechnology and pharmaceutical industries, taking
        into account relative company size, stage of development, performance
        and geographic location as well as individual responsibilities and
        performance.

   -    Align the interests of management and stockholders and enhance
        stockholder value by providing management with longer term incentives
        through equity ownership by management.

KEY ELEMENTS OF EXECUTIVE COMPENSATION

   Through 1996, the Company was focused on the development of proprietary
products such as the GenESA System, continuing to make progress in advancing its
research programs and investing in the long term value of Gensia Laboratories.

   The Company has not yet brought any proprietary products to market so the
use of traditional corporate performance standards, such as revenues, profits
and return on equity were not appropriate in the evaluation of executive officer
performance.  Accordingly, there is no specific relationship of traditional
corporate performance standards to executive compensation.  Therefore, the
Compensation Committee has determined that compensation of executive officers
will be based, in part, on the Company's achievements of its objectives
established with the Board of Directors as well as accomplishing other business
objectives, as well as the individual contributions and achievements of each
executive officer.  The Company's existing compensation structure for executive
officers generally includes a combination of base salary, bonus, and stock
options.

                                      -14-
<PAGE>

   BASE SALARY

   Compensation levels are largely determined through comparisons with 
companies of similar size and/or complexity in the biotechnology and 
pharmaceutical industries and/or companies with which the Company competes 
for key personnel.  Cash compensation for the Company's executive officers, 
including its Chief Executive Officer, is generally targeted at the median of 
the companies reviewed.  As stated above, because the Company is still 
developing its proprietary products and so has not yet brought any such 
products to market, the use of traditional corporate performance standards, 
such as profit levels, revenues and return on equity, was not appropriate in 
the evaluation of executive officer performance in 1996.  In establishing 
base salaries  for 1996, the Committee instead considered, among other 
things, the Company's achievements in advancing its products and 
accomplishing other business objectives, and the individual contributions and 
achievements of each executive officer.  Actual compensation is based on an 
evaluation of job responsibilities for the position, comparisons of 
compensation levels, Company achievements and individual performance.  
Individual performance is evaluated by reviewing organizational and 
management development progress against individual contributions and 
achievements and the degree to which teamwork and Company values are 
fostered.  At the beginning of fiscal 1996, goals were established for the 
Company and approved by the Board of Directors.  Goals set for 1996 included 
increasing revenues for Gensia, Inc., obtaining approval of certain 
Abbreviated New Drug Applications ("ANDAs") and filing additional ANDAs for 
approval, completing corporate partnerships to support the Company's research 
programs, beginning clinical studies of the Feedback Controlled Heparin 
System (the "FCHS") and continuing development of the Company's products that 
are in clinical development.  Further, compensation levels for the executive 
officers are competitive within a range that the Committee considers to be 
reasonable and necessary.

   BONUS

   The Committee may award bonuses under its Key Employee Incentive Plan at 
the end of the fiscal year based on the Company's achievements and the 
individual's contributions to those achievements, if it deems such an award 
to be appropriate.  This award may be in the form of restricted stock in lieu 
of cash.  While the Committee may award cash bonuses from time to time in the 
future, it currently intends to award the majority of bonuses in the form of 
restricted stock or options.  Based on the Company's achievement of a number 
of key objectives in 1996 that were important for the continued growth and 
development of the Company, including entering into the Stock Exchange 
Agreement with Rakepoll Finance; obtaining approval of certain ANDAs and the 
filing of key additional ANDAs at Gensia Laboratories, raising additional 
financial resources for the Company; and licensing-in additional products for 
commercialization by the Gensia sales and marketing organization, the 
Committee decided to award restricted stock in lieu of cash bonuses for 1996 
to certain officers and key employees.

   STOCK OPTIONS

   The Company's 1990 Stock Plan and 1997 Stock Plan are administered by the 
Company's Stock Option Committee, which is a committee of outside directors 
of the Company.  The Stock Option Committee believes that by providing those 
persons who have substantial responsibility for the management and growth of 
the Company with an opportunity to increase their ownership of Company stock, 
the best interest of stockholders and executives will be closely aligned. 
Therefore, executive officers, as well as all employees, are eligible to 
receive stock options from time to time, giving them the right to purchase 
shares of Common Stock of the Company at a specified price.  The number of 
stock options granted to executive officers, including the Chief Executive 
Officer, is based on the Company's achievements during the year and the 
individual's contributions to those achievements and a review of data on the 
range of aggregate annual option grants compared to the number of shares of 
stock outstanding for officers with similar duties and titles at 
biotechnology companies taking into account differences in such companies' 
stock prices, stage of development, achievements and the like.

                                      -15-
<PAGE>

1996 CEO COMPENSATION

   Because the Company did not achieve all of its major objectives and 
because of the difficult financing environment for the Company, the Committee 
did not award a salary increase to Mr. Hale for 1997.  As the Company is 
still developing its proprietary products and so has not yet brought any such 
products to market, the use of traditional performance standards, such as 
revenues, profits and return on equity, are not appropriate in the evaluation 
of Mr. Hale's performance.  The Company and Mr. Hale achieved a number of the 
corporate objectives for 1996.  Some of these achievements were as follows:  
the filing of six ANDAs at Gensia Laboratories, establishment of a strategic 
partnership with Pfizer, Inc. to develop compounds for the treatment of pain 
which supported certain of the company's research and development expenses, 
submission of a New Drug Application amendment for the GenESA System with 
additional clinical data on over 1,000 patients, completion of prototype 
development and the beginning of clinical studies of the FCHS, continuing 
development of its proprietary products, and negotiation and consummation of 
a stock exchange agreement with Rakepoll Finance.  The Compensation Committee 
determined that these achievements were critical to the Company's future 
growth and could assist the Company in enhancing stockholder value and 
determined to compensate Mr. Hale for his role in achieving these 
accomplishments. Accordingly, the Committee awarded a bonus under the 
Company's Key Employee Incentive Compensation Plan in the form of restricted 
stock of 18,804 shares of Common Stock.

   The Stock Option Committee did not grant Mr. Hale any new options to 
purchase shares of the Company's Common Stock in 1996.

MISCELLANEOUS

   Section 162(m) of the Internal Revenue Code was enacted in 1993 and took 
effect for fiscal years beginning in 1994.  Section 162(m) disallows the 
deductibility by the Company of any compensation over $1 million per year 
paid to each of the chief executive officer and the four other most highly 
compensated executive officers, unless certain criteria are satisfied.  The 
Board of Directors has approved the amendment of the Company's 1990 Stock 
Plan to, among other things, qualify for an exemption from the $1 million 
limit on deductions under Section 162(m) with respect to option grants under 
the 1990 Stock Plan.  The 1997 Long-Term Incentive Plan, which replaced the 
1990 Stock Plan in February 1997 also qualifies for such exemption with 
respect to grants under such plan.

   This Compensation Committee Report shall not be deemed incorporated by 
reference by any general statement incorporating by reference this proxy 
statement into any filing under the Securities Act of 1933 or under the 
Securities Exchange Act of 1934, except to the extent the Company 
specifically incorporates this report by reference, and shall not otherwise 
be deemed filed under such Acts.

   COMPENSATION COMMITTEE             STOCK OPTION COMMITTEE

   James C. Blair                     James C. Blair
   Herbert J. Conrad                  Herbert J. Conrad
   Carlo Salvi

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

   The members of the Compensation Committee and Stock Option Committee 
during 1996 were James C. Blair, Herbert J. Conrad, Steven C. Mendell and 
Jerry C. Benjamin.  Mr. Mendell and Mr. Benjamin resigned as directors and 
committee members in March 1997 and May 1997, respectively in order to permit 
the required appointment of directors pursuant to the Shareholders Agreement 
and the Purchase Agreement.

                                      -16-
<PAGE>

                        STOCK PRICE PERFORMANCE GRAPH

   The following graph illustrates a comparison of the cumulative total 
stockholder return (change in stock price plus reinvested dividends) of the 
Company's Common Stock with the CRSP Total Return Index for The Nasdaq Stock 
Market (U.S. and Foreign) (the "Nasdaq Composite Index") and the CRSP Total 
Return Index for Nasdaq Pharmaceutical Stocks (the "Nasdaq Pharmaceutical 
Index").  The comparisons in the graph are required by the Securities and 
Exchange Commission and are not intended to forecast or be indicative of 
possible future performance of the Company's Common Stock.

<TABLE>
<CAPTION>

                           12/31/91  12/31/92  12/31/93  12/31/94  12/30/95  12/31/96
                           --------  --------  --------  --------  --------  --------
<S>                        <C>       <C>       <C>       <C>       <C>       <C>
Gensia Sicor                $100.00   $ 70.67   $ 71.39   $ 12.25   $ 15.14   $ 13.35
Nasdaq Composite             100.00    116.03    134.32    130.28    182.96    224.06
Nasdaq Pharmaceutical        100.00     83.22     74.17     55.83    102.13    102.44
</TABLE>

   Assumes a $100 investment on December 31, 1991 in each of the Company's 
Common Stock, the securities comprising the Nasdaq Composite Index, and the 
securities comprising the Nasdaq Pharmaceutical Index.

   The Nasdaq Pharmaceutical Index includes all companies listed on The 
Nasdaq Stock Market within SIC Code 283.  A list of those companies included 
in the Nasdaq Pharmaceutical Index may be obtained by contacting Wesley N. 
Fach, Secretary, at (619) 546-8300.

                                      -17-
<PAGE>

                             CERTAIN TRANSACTIONS

THE STOCK EXCHANGE

   On February 26, 1997 the stockholders of Gensia approved the Stock 
Exchange Agreement between Gensia and Rakepoll Finance pursuant to which, 
Gensia acquired all of the outstanding shares of capital stock of Rakepoll 
Holding pursuant to the Stock Exchange.  As a result of the Stock Exchange, 
Rakepoll Holding became a wholly-owned subsidiary of Gensia Sicor.  Rakepoll 
Holding is a Netherlands holding company which owns a group of three 
specialty pharmaceutical companies (the "Rakepoll Operating Group") comprised 
of Sicor, located in Milan, Italy, and two companies located in Mexico, 
Lemery, S.A. de C.V. ("Lemery"), and Sicor de Mexico, S.A. de C.V. ("Sicor de 
Mexico").  Sicor and Sicor de Mexico manufacture specialty bulk drug 
substances. Lemery produces oral and injectable finished multisource drug 
products (also called finished dosage forms) utilizing specialty bulk drug 
substances produced by the other companies in the Rakepoll Operating Group 
and/or purchased from third parties.  The specialty bulk drug substances 
manufactured by the Rakepoll Operating Group are almost entirely destined for 
parenteral or topical administration, including inhalation therapy, and 
almost all belong to one of three categories: (i) oncolytic agents, (ii) 
steroids or (iii) non-depolarizing muscle relaxants.

   In addition, pursuant to the Shareholder's Agreement entered into in 
connection with the Stock Exchange Agreement, if Rakepoll Finance maintains 
certain equity ownership levels in Gensia Sicor, Rakepoll Finance will be 
entitled to designate three of Gensia Sicor's 10 directors who will in turn 
designate (jointly with two executive officer directors of Gensia Sicor) five 
additional directors.  See "Election of Directors."  The Shareholder's 
Agreement further granted to Rakepoll Finance the right to initially 
designate a majority of the directors and the senior managers of each of 
Sicor, Sicor de Mexico and Lemery, and grants to the Investor Directors the 
right to nominate for the consideration of the Gensia Sicor Board of 
Directors replacements for all directors and senior managers so designated. 
The Management Directors are entitled to designate the balance of the 
directors and senior managers of each such company. Each such director and 
senior manager shall serve at the pleasure of the Board of Directors of 
Gensia Sicor. Additionally, with respect to Gensia Laboratories, the 
Shareholder's Agreement set forth the composition of the Board of Directors 
thereof upon consummation of the Stock Exchange (the "Closing Date") and 
provided that Rakepoll Finance has the right to designate one of the 
directors thereof.

   The Shareholder's Agreement provided that, at the Closing Date (i) an 
Independent Director shall serve as the non-executive Chairman of the Gensia 
Sicor Board of Directors, (ii) David F. Hale shall serve as President and 
Chief Executive Officer of Gensia Sicor and (iii) Michael D. Cannon shall 
serve as Executive Vice President of Gensia Sicor.  The Shareholder's 
Agreement further provides for the creation of an Executive Operating 
Committee, to be a management committee and not a committee of the Board of 
Directors of Gensia Sicor, consisting of Carlo Salvi (to serve as the 
Executive Operating Committee's Chairman), the President and Chief Executive 
Officer of Gensia Sicor, the President of Gensia Laboratories and the 
Executive Vice President of Gensia Sicor.

   Pursuant to the Shareholder's Agreement, the consent of the Investor 
Directors will be required for Gensia Sicor to take certain actions, such as 
a merger or sale of all or substantially all of the business or assets of 
Gensia Sicor and certain issuances of securities.   The Shareholder's 
Agreement also grants certain anti-dilution privileges to Rakepoll Finance 
and places limitations on Rakepoll Finance's ability to acquire or dispose of 
any Gensia Sicor Common Stock for eighteen months from the Closing Date.

   As a result of the Stock Exchange all options to acquire Gensia Common 
Stock held by each of the executive officers and directors of Gensia Sicor 
became fully vested upon the consummation of the Stock Exchange.  In addition 
because the Stock Exchange constituted a change in control pursuant to 
agreements Gensia had executed with its officers and certain key employees of 
Gensia, including David F. Hale, President and Chief Executive Officer of 
Gensia Sicor, each such individual became entitled to certain benefits, 
including salary continuation and healthcare coverage upon, within a certain 
period of time, their resignation for good

                                      -18-
<PAGE>

reason, including, without limitation, changes in job authority or 
responsibility or employer's physical location, or termination of their 
employment for other than cause or disability.  Also, in November 1996, the 
Gensia Board of Directors (with Mr. Hale not present) agreed to forgive, upon 
consummation of the Stock Exchange, a loan made by Gensia to Mr. Hale in 
April 1995, upon terms to be determined by the Company's Compensation 
Committee. The outstanding principal and interest on such loan was 
approximately $150,000.  In addition, Gensia and Rakepoll Finance have each 
agreed to cause Gensia Sicor to (a) maintain and perform in the same manner 
as prior to the execution date of the Stock Exchange Agreement Gensia's 
existing indemnification provisions with respect to its present and former 
directors and officers for acts or omissions or alleged acts or omissions 
occurring at or prior to the Closing Date, subject to certain limitations, 
(b) to provide, maintain and perform in the same manner as prior to the 
execution date of the Stock Exchange Agreement Gensia's existing 
indemnification provisions with respect to its present and future directors 
and officers for acts or omissions or alleged acts or omissions occurring 
after the Closing Date, subject to certain limitations, and (c) maintain for 
a period of no less than three years after the Closing Date, directors and 
officers liability coverage with limits, terms and conditions no less 
advantageous than Gensia had in effect as of the execution date of the Stock 
Exchange Agreement. The Gensia Board of Directors was aware of these 
interests and took these interests into account in approving the Stock 
Exchange Agreement and the transactions contemplated thereby, including the 
Stock Exchange and the Shareholder's Agreement.

   Mr. Salvi is the beneficial owner of a majority of Rakepoll Finance.  Mr. 
Cannon is the beneficial owner of less than ten percent of Rakepoll Finance.

RELATIONSHIP WITH GENSIA CLINICAL PARTNERS

   In July 1991, the Company organized Gensia Clinical Partners to provide 
funding for further research and clinical development of the Company's 
GenESA-Registered Trademark- System technology.  Gensia Clinical Partners 
received net proceeds of approximately $23.0 million from its limited 
partners, all of which has been paid to the Company pursuant to a research 
and development contract.  Gensia Development Corporation, a wholly-owned 
subsidiary of the Company, is the sole general partner of Gensia Clinical 
Partners.

   The Company has granted Gensia Clinical Partners an exclusive royalty-free 
license to use certain patent rights and technology that are related to the 
GenESA System in the United States, Canada and Europe.  Under its development 
and marketing agreement with Gensia Clinical Partners, the Company conducts 
research and development relating to the GenESA System, and Gensia Clinical 
Partners reimbursed the Company for these services through May 1993.  The 
full amount of proceeds from the partnership were utilized as of May 1993 and 
the Company has continued funding all further expenses related to the GenESA 
System. The Company is obligated under the agreements to market the GenESA 
System in the United States, Canada and certain countries in Europe, if 
approved by regulatory authorities in these countries, and to pay royalties 
based on those sales.  In addition, the Company is required to make a 
milestone payment of approximately $5 million payable in cash or Common Stock 
of the Company upon approval of the GenESA System by the United States Food 
and Drug Administration.  In the second quarter of 1997, the FDA advised 
Gensia Sicor that the GenESA System is approvable for use in conjunction with 
radionuclide perfusion imaging and echocardiography for patients unable to 
exercise adequately.  Approval of the produce in the U.S. is contingent on 
acceptance by the FDA of final labeling. The Company expects to launch the 
product in the U.S. through its hospital base sales organization in the third 
quarter of 1997.

   During the two to four-year period following the initial commercialization 
of the GenESA System, the Company has the option to purchase the limited 
partners' interests in Gensia Clinical Partners.  If the Company exercises 
this option, it will pay the limited partners approximately $22 million 
payable in cash or shares of Common Stock of the Company (the "Advance 
Payment"), and a royalty on product sales of the GenESA System for an 
eleven-year period following the purchase of the interests.  At a limited 
partner's option, in lieu of the right to receive the Advance Payment and 
royalty, a limited partner may elect to receive a predetermined number of 
shares of Common Stock of the Company.  If all limited partners were to elect 
this option, the Company would issue 1,976,250 shares of Common Stock of the 
Company (and would not be required to

                                      -19-
<PAGE>

make the Advance Payment or pay any royalty).  In return for the option to 
purchase the partnership interests in Gensia Clinical Partners, the Company 
issued warrants to the limited partners to purchase 2,249,175 shares of 
Common Stock of the Company.  If the Company fails to exercise its option, 
the Company will lose all rights to the GenESA System in the United States, 
Canada and Europe.  The Company contributed approximately $3.2 million for 
funding of expenses related to the GenESA System during 1996.

RELATIONSHIP WITH GENTA/JAGOTEC JOINT VENTURE

   In January 1993, Gensia and a joint venture ("Genta-Jago") between Genta 
Incorporated and Jagotec AG, an affiliate of Jago Pharma AG which was 
acquired by SkyePharma PLC ("SkyePharma") in May 1996, formed a collaboration 
to develop and market certain oral products for the treatment of 
cardiovascular disease using Geomatrix controlled-release drug delivery 
technology.  In February 1996, Gensia informed Genta-Jago that it would be 
focusing its efforts in the future on Geomatrix nifedipine and that it would 
not pursue development of the Geomatrix formulations of verapamil and 
metaprolol.  Effective on October 1, 1996 Gensia Sicor transferred its rights 
under the collaboration to Brightstone Pharma, Inc. ("Brightstone"), 
SkyePharma's U.S. subsidiary.  Brightstone Pharma Inc. will pay Gensia Sicor 
a royalty from its share of operating income, if any, derived from any 
Geomatrix nifedipine products marketed by Brightstone and Boehringer Mannheim 
Corporation.  In 1996 Gensia paid $2.3 million in development funding prior 
to transferring its rights.

   David F. Hale, President and Chief Executive Officer of the Company and 
James C. Blair, a director of the Company, were directors of Genta 
Incorporated until their resignations in October 1996 and January 1997, 
respectively, and Thomas H. Adams, the former chairman of the Board and 
former Chief Executive Officer of Genta Incorporated, was a member of 
Gensia's Scientific Advisory Board until 1996.

RELATIONSHIP WITH ALCO CHEMICALS, LTD.

   Alco, an affiliate of Rakepoll Finance and wholly-owned by Carlo Salvi, 
acts as a non-exclusive sales agent for certain bulk pharmaceutical products 
produced by certain subsidiaries of the Company, in exchange for a commission 
of 4% of sales.  The parties will determine, from time to time, those bulk 
pharmaceutical products for which Alco will act as a sales agent.

OTHER TRANSACTIONS

   The Company paid Domain Partners III, L.P. ("Domain III") $75,000 as 
partial consideration for financial commitments made by Domain III in 
connection with the possible funding of the development of a new product 
opportunity involving a feedback controlled heparin drug delivery system (the 
"Automedics Project").  In February 1996, the Board authorized the issuance 
of a warrant to purchase up to 50,000 shares of the Company's Common Stock to 
Domain III as partial consideration for financial commitments made in 
furtherance of the Automedics Project.  During 1995, Domain III made a loan 
in the principal amount of $250,000 to Gensia Automedics, in connection with 
the Automedics Project. The loan, along with accrued interest in the amount 
of $13,636, was repaid on January 2, 1996.  Dr. Blair, a director of the 
Company, is a general partner of One Palmer Square Associates III, L.P., the 
general partner of Domain III.

   Ian McBeath, Vice President of Gensia Europe Limited until April 8, 1996, 
was indebted to the Company in the aggregate amount of approximately L47,400. 
The indebtedness was evidenced by two loans, one secured by real property and 
the other unsecured.  The principal amount of the secured loan was L27,000 
with an interest rate of 5% per annum.  The principal amount of the unsecured 
loan, an interest free loan, was L18,014.  Although Mr. McBeath resigned as 
an officer of the Company on April 8, 1996, he continued to render consulting 
services through July 1, 1996, at which time the secured loan and the 
unsecured loan and L2,700 in interest thereon became due and was paid.

                                      -20-
<PAGE>

   The Wilkerson Group has provided market research and consulting services 
to the Company in 1996 for which the Company has paid The Wilkerson Group 
approximately $102,000.  Dr. Wilkerson, a director of the Company, was an 
affiliate of The Wilkerson Group until May 1996.

   Two relocation loans were previously made by the Company to Patrick D. 
Walsh, President and Chief Operating Officer of Gensia Laboratories.  One of 
the loans, in the principal amount of $35,000 was repaid in 1996.  Mr. Walsh 
is indebted to the Company in the aggregate principal amount of $100,000 with 
respect to the other loan.  Interest at the rate of 5% per annum is payable 
on the loan.  Accrued interest as of March 31, 1997 is approximately $13,000. 
The loan is secured by real property and is due on October 12, 1999.

   On June 26, 1996 the Company made an interest free relocation loan to Gene 
F. Tutwiler, Vice President, Corporate Development.  Dr. Tutwiler is indebted 
to the Company in the principal amount of $100,000 with respect to the loan.  
The loan is secured by real property and is due on June 25, 2001.  Commencing 
July 1, 1996 the Company has agreed to forgive 25% of the loan each year Dr. 
Tutwiler continues to be employed by the Company.

   In March and April 1997 the Company sold 4,150,440 Units to certain 
accredited investors in a private placement, at a purchase price of $4.1875 
per Unit.  Each Unit consists of one share of Common Stock and a warrant for 
the purchase of one-half share of Common Stock, at an exercise price of 
$4.1875 per share, for each share of Common Stock purchased in the Unit 
offering and held until December 31, 1997.  The following Gensia Sicor 
directors participated in the Unit offering:  Mr. Salvi, 100,000 Units; Mr. 
Panoz, 50,000 Units; Dr. Blair, 24,000 Units; and Mr. Hale, 10,000 Units.

   On May 19, 1997 Health Care Capital purchased $20 million in convertible 
notes due in 2004 and warrants to purchase up to 2,645,503 shares of Gensia 
Sicor Common Stock at $4.35 per share.  The notes bear a coupon of 2.675%.  
The notes are convertible into Gensia Sicor Convertible Preferred Stock or 
Common Stock at a conversion price of $3.78 per share.  Fifty percent of the 
warrants are conditional warrants that may not be exercised for three years 
and will be cancelled if the Gensia Sicor Common Stock price exceeds certain 
levels during the first three years of the loan.  Pursuant to the terms of 
the Purchase Agreement so long as Health Care Capital or its related entities 
own at least $10 million of the notes or the Convertible Preferred Stock the 
notes are convertible into, it is entitled to have one Class II director 
nominated for election and such director shall be a member of the Company's 
Executive Committee.  See "Election of Directors."

   The Company believes that the foregoing transactions were in its best 
interests.  It is the Company's current policy that all transactions by the 
Company with officers, directors, 5% stockholders or their affiliates will be 
entered into only if such transactions are approved by a majority of the 
disinterested directors, and are on terms no less favorable to the Company 
than could be obtained from unaffiliated parties.

                                  PROPOSAL 2
               APPROVAL OF THE AMENDMENT AND RESTATEMENT OF THE
                GENSIA SICOR INC. EMPLOYEE STOCK PURCHASE PLAN

   In order to provide employees of the Company with an opportunity to
purchase Common Stock through payroll deductions, the Board of Directors
originally adopted the Gensia, Inc. Employee Stock Purchase Plan in 1992 under
which 300,000 shares of Common Stock were reserved for issuance.  The plan was
amended and restated in 1996 to reserve an additional 100,000 shares for
issuance.  In June 1997, the Board of Directors amended and restated the plan
(as amended and restated, the "ESPP") to reserve an additional 100,000 shares
for issuance under the ESPP and to rename the ESPP the Gensia Sicor Inc.
Employee Stock Purchase Plan, subject to the approval of the Company's
stockholders at the Annual Meeting.  As of July 31, 1997, an aggregate of 27,883
shares were available for issuance under the ESPP.

                                      -21-
<PAGE>

   The full text of the ESPP, substantially in the form in which it will take 
effect if the ESPP is approved by the stockholders, is set forth in Exhibit A 
to this Proxy Statement.  The following description of the ESPP is a summary 
only. It is subject to, and qualified in its entirety by, Exhibit A.

   Under the ESPP, an aggregate of 500,000 shares of Common Stock (which 
number includes the 100,000 share increase that stockholders are being asked 
to approve) have been reserved for issuance, subject to anti-dilution 
adjustments. Any full-time employee will be eligible to participate in the 
ESPP after he or she has been continuously employed by the Company for three 
consecutive months. Eligible employees may elect to contribute up to 12% of 
their total compensation during each six-month offering period, subject to 
certain statutory limits.  At the end of each six-month offering period, the 
Company will apply the amount contributed by the participant during the 
offering period to purchase whole shares of Common Stock, but not more than 
1,000 shares.  Shares of Common Stock are purchased for 85% of the lower of 
(i) the market price of the Common Stock immediately before the beginning of 
the purchase period or (ii) the market price of such Common Stock on the last 
business day of the purchase period.  All expenses incurred in connection 
with the implementation and administration of the ESPP will be paid by the 
Company.

FEDERAL INCOME TAX CONSEQUENCES

   The ESPP is intended to qualify as an "employee stock purchase plan" under 
section 423 of the Code.  No income is recognized by a participant at the 
time a right to purchase Company Common Stock is granted.  Likewise, no 
taxable income is recognized at the time of the purchase, even though the 
purchase price reflects a discount from the market value of the shares at 
that time.

   A participant must recognize taxable income upon a disposition of shares 
acquired under the ESPP.  The tax treatment may be more favorable if the 
disposition occurs after the holding-period requirements of section 423 have 
been satisfied.  To satisfy the holding-period requirements of section 423, 
shares acquired under the Plan cannot be disposed of within two years after 
the FIRST day of the offering period during which the shares are purchased.  
They also cannot be disposed of within one year after they are purchased.

   If the holding period is met, the participant recognizes ordinary income 
equal to the LOWER of (a) the excess of the fair market value of the shares 
on the date of the disposition over the actual purchase price or (b) 15% of 
the fair market value of the shares immediately before the applicable 
offering period.  The Company will not be entitled to any deduction under 
these circumstances.

   The excess, if any, of the fair market value of the shares on the date of 
the disposition over the sum of the purchase price plus the amount of 
ordinary income recognized (as described above) will be taxed as a long-term 
capital gain.  If a taxable disposition produces a loss (i.e., the fair 
market value of the shares on the date of the disposition is less than the 
purchase price) and the disposition involves certain unrelated parties, then 
the loss will be a long-term capital loss.

   If the holding period is not met, the entire difference between the 
purchase price and the market value of the shares on the date of purchase 
will be taxed to the participant as ordinary income in the year of 
disposition.  The Company will generally be entitled to a deduction for the 
same amount.

   The excess, if any, of the market value of the shares on the date of 
disposition over their market value on the date of purchase will be taxed as 
a capital gain (long term or short-term, depending on how long the shares 
have been held).  If the value of the shares on the date of disposition is 
less than their value on the date of purchase, then the difference will 
result in a capital loss (long-term or short-term, depending upon the holding 
period), provided the disposition involves certain unrelated parties.  Any 
such loss will not affect the ordinary income recognized upon the disposition.

                                      -22-
<PAGE>

   1997 TAX LAW

   In August 1997 new tax legislation was enacted (the "1997 Tax Law") which 
provides for lower capital gains rates if stock is held for eighteen months. 
The 1997 Tax Law also provides for even lower applicable capital gains rates 
for stock acquired after December 31, 2000 in certain circumstances if the 
stock is held for at least five years.

  THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE ADOPTION OF THE AMENDMENT
    AND RESTATEMENT OF THE GENSIA SICOR INC. EMPLOYEE STOCK PURCHASE PLAN.

                                  PROPOSAL 3
               APPROVAL OF THE AMENDMENT AND RESTATEMENT OF THE
                GENSIA SICOR INC. 1997 LONG-TERM INCENTIVE PLAN

   At the special meeting of stockholders approving the Stock Exchange, the 
stockholders of the Company also approved the adoption of the Gensia Sicor 
Inc. Long-Term Incentive Plan, under which 2,000,000 shares of Common Stock 
have been reserved for issuance under the such plan.  On June 20, 1997, the 
Board of Directors amended and restated the plan (as amended and restated, 
the "1997 Stock Plan") to reserve an additional 1,000,000 shares for issuance 
under the plan, subject to the approval of the Company's stockholders at the 
Annual Meeting.  The 1997 Stock Plan replaced the Company's 1990 Stock Plan 
(the "1990 Stock Plan") effective February 26, 1997 and any shares not 
subject to exercise under the 1990 Stock Plan or which are not exercised 
because of forfeiture or termination of options granted under the 1990 Stock 
Plan are added to the shares available under the 1997 Stock Plan.  The full 
text of the 1997 Stock Plan, substantially in the form in which it will take 
effect if approved by the Company's stockholders, is set forth in Exhibit B 
to this Proxy Statement. The following summary of the principal features of 
the 1997 Stock Plan is subject to, and qualified in its entirety by, Exhibit 
B.

DESCRIPTION OF 1997 STOCK PLAN

   PURPOSE

   The purpose of the 1997 Stock Plan is to promote the interests of the 
Company and its stockholders by encouraging key individuals to acquire stock 
or to increase their proprietary interest in the Company. By providing the 
opportunity to acquire stock or receive other incentives, the Company seeks 
to attract and retain those key employees upon whose judgment, initiative and 
leadership the success of the Company largely depends.  While the maximum 
number of shares available for award is modest in comparison to the total 
number of shares of the Company Common Stock outstanding, the Company's Board 
of Directors believes that the 1997 Stock Plan will constitute an important 
means of compensating key employees.

   SHARES SUBJECT TO 1997 STOCK PLAN

   There are 3,000,000 shares of Company Common Stock reserved for issuance 
under the 1997 Stock Plan.  The 1997 Stock Plan replaced the 1990 Stock Plan. 
Under the 1990 Stock Plan, 6,383,334 shares of Company Common Stock have been 
reserved for issuance.  The 1990 Stock Plan provided for the grant of both 
incentive stock options to employees only and nonstatutory stock options to 
employees, directors and independent consultants.  The 1990 Stock Plan also 
provided for direct sale of shares to employees, directors and outside 
consultants.  If any options granted under the 1990 Stock Plan for any reason 
expire or are cancelled or otherwise terminated without having been exercised 
in full, the shares allocable to the unexercised

                                      -23-
<PAGE>

portion of such options again become available for new grants under the 1997 
Stock Plan.  If shares issued under the 1990 Stock Plan are forfeited, they 
also become available for new grants under the 1997 Stock Plan.

   OUTSTANDING GRANTS

   As of July 31, 1997, options to purchase an aggregate of 4,786,356 shares 
of Company Common Stock at a weighted average exercise price of $5.69 per 
share were outstanding under both the 1990 Stock Plan and the 1997 Stock 
Plan.  The foregoing numbers do not include options granted to former 
employees.  As of July 31, 1997, approximately 551 employees, 9 directors and 
43 consultants or advisors were eligible to participate in both plans.  On 
August 8, 1997, the closing price of the Company's Common Stock on the Nasdaq 
National Market was $4.50 per share. To date, all employee stock options have 
been granted with exercise prices equal to the fair market value of the 
Company's Common Stock on the date of grant, as determined by the Stock 
Option Committee in accordance with the provisions of the plans.  Of the 
options granted, 1,098,033 shares have been exercised.  As of July 31, 1997, 
86,250 shares of Company Common Stock had been issued for direct sale under 
the plans.  As of July 31, 1997, a total of 893,330 shares of Company Common 
Stock were available for future awards under the 1997 Stock Plan.  No shares 
remain available for grant under the 1990 Stock Plan.

   As of July 31, 1997, the following persons or groups had in total received 
options to purchase shares of Company Common Stock under either the 1990 
Stock Plan or the 1997 Stock Plan:  (i) the Chief Executive Officer and the 
other remaining officers named in the Summary Compensation Table:  Mr. Hale 
647,500 shares, Mr. Walsh 145,000 shares, Mr. Burgess 112,500 shares, Dr. 
Laikind 92,500 shares, and Dr. Tutwiler 50,000 shares; (ii) all current 
executive officers of the Company as a group:  1,434,600 shares; (iii) all 
current directors who are not officers as a group 850,500 shares; (iv) each 
associate of any of such current directors, executive officers or nominees:  
0 shares; (v) each person who has received five percent of options granted 
other than those included above: 0 shares; and (vi) all employees and 
consultants of the Company 4,019,369 shares.  The foregoing numbers do not 
include options that were surrendered in connection with the grant of 
restricted stock awards.

   ADMINISTRATION

   The 1997 Stock Plan is administered by the Stock Option Committee (the 
"Committee"), composed of directors who are disinterested persons under Rule 
16b-3 of the Exchange Act ("Rule 16b-3") or Code Section 162(m) and smaller 
committees of directors as established by the Company's Board.  In the case 
of grants to persons who are not also insiders for purposes of Section 16 of 
the Exchange Act, the 1997 Stock Plan may be administered by officers who are 
not directors.  The Company's Board may fill vacancies from time to time to 
remove or add members.

   The Committee selects those employees of the Company or its subsidiaries 
who will be eligible to receive awards under the 1997 Stock Plan.  The 1997 
Stock Plan provides that the Committee may grant to eligible individuals any 
combination of nonqualified stock options, incentive stock options, 
restricted stock, stock appreciation rights, performance awards, stock 
payments or dividend equivalents.  Each grant will be memorialized in a 
separate agreement with the person receiving the grant.  This agreement will 
indicate the type and terms of the award.

   NON-EMPLOYEE DIRECTOR GRANTS

   Non-employee directors are eligible to receive nonqualified stock options 
under the 1997 Stock Plan in the sole discretion of the Company's full Board. 
These grants are designed to comply with the provisions of Rule 16b-3 and are 
made at the conclusion of each regular annual meeting of stockholders to 
selected

                                      -24-
<PAGE>

incumbent non-employee directors who will continue to serve on the Company's 
Board thereafter.  The shares of Company Common Stock may be issued for past 
service by the non-employee directors and without payment of any purchase 
price.  New non-employee directors may receive initial grants of nonqualified 
stock options unless they had received an initial grant at the conclusion of 
the annual stockholder meeting in the same calendar year.

   Total shares available to non-employee directors may not exceed 15% of the 
maximum number of shares available under the 1997 Stock Plan.

   STOCK OPTIONS

   Nonqualified stock options provide the right to purchase shares of Company 
Common Stock at a price which is not less than 85% of the fair market value 
of Company Common Stock subject to the option on the effective date of the 
grant. These options are granted for a term which may not exceed ten years.

   Incentive stock options comply with the provisions of the Code and are 
subject to restrictions contained in the Code.  Incentive stock options are 
granted with an exercise price of not less than 100% of the fair market value 
of the Company Common Stock subject to the option on the date of grant and 
will extend for a term of up to ten years. Incentive stock options granted to 
persons who own more than 10% of the combined voting power of the Company's 
outstanding securities must be granted at prices which are not less than 110% 
of fair market value on the date of grant and may not extend for more than 
five years from the date of grant.

   The option exercise price must be paid in full at the time of exercise. 
The price may be paid in cash or, as acceptable to the Committee, by loan 
made by the Company to the participant, by arrangement with a broker where 
payment of the option price is guaranteed by the broker, by the surrender of 
shares of the Company owned by the participant exercising the option and 
having a fair market value on the date of exercise equal to the option price, 
or by any combination of the foregoing equal to the option price.

   Options for employees have such other terms and are exercisable in such 
manner and at such times as the Committee may determine.  As noted below, all 
awards under the 1997 Stock Plan vest fully and immediately upon death, 
disability or upon a change in control. In addition, an option agreement for 
an employee may provide for accelerated exercisability in the case of other 
events as determined by the Committee.

   The Committee may, at any time prior to exercise and subject to consent of 
the participant, amend, modify or cancel any options previously granted and 
may or may not substitute in their place options at a different price and of 
a different type under different terms or in different amounts.

   RESTRICTED STOCK

   Restricted stock may be granted or sold to employees for prices determined 
by the Committee and subject to such restrictions as may be appropriate. 
Typically restricted stock is forfeited and is resold to the Company at cost 
in the event that "vesting" is not achieved by virtue of seniority or 
performance or other criteria.  In general, restricted shares may not be 
sold, transferred or hypothecated until restrictions are removed or expire.  
Purchasers of restricted stock, unlike recipients of options, have voting 
rights and receive dividends, if any, prior to the time when the restrictions 
lapse.

                                      -25-
<PAGE>

   STOCK APPRECIATION RIGHTS

   Stock appreciation rights ("SARs") may be granted in tandem with stock 
options or separately.  If SARs are granted in tandem with options, the 
options may be either nonqualified or incentive stock options.  SARs granted 
by the Committee in tandem with stock options will provide for payments to 
grantees based upon increases in the price of Company Common Stock over the 
exercise price of the related option.  The SARs will provide that the holder 
of the SARs may exercise the SARs or the option in whole or in part, but the 
aggregate exercise may not cover more than the aggregate number of shares 
upon which the value of the SARs is based.  SARs granted in tandem with 
options may not extend beyond the term of the related option.  SARs will be 
transferable only to the extent that the related option is transferable.  The 
Committee may elect to pay SARs in cash or in Company Common Stock or in a 
combination of cash and Company Common Stock.

   SARs which are issued separately from options will provide for payments 
based upon increases in the price of Company Common Stock over the fair 
market value of Company Common Stock or the book value of Company Common 
Stock on the date of grant. The Committee will determine whether fair market 
value or book value will be the appropriate measure. As with other SARs, upon 
exercise the Committee may determine to pay the SARs in cash or in Company 
Common Stock or in a combination of cash and Company Common Stock.

   PERFORMANCE AWARDS, COMMON STOCK PAYMENTS AND DIVIDEND EQUIVALENTS

   Performance awards may be granted by the Committee on an individual basis. 
Generally these awards will be paid in cash and will be based upon specific 
agreements.

   The Committee may approve a payment in Company Common Stock to any 
employee who otherwise may be entitled to a cash payment other than base 
salary (e.g., a bonus).  Similarly, the Committee may award shares as 
dividend equivalents with respect to grants of options or SARs.

   SECTION 162(m)

   In order to permit maximum deductibility of compensation relating to 
awards of stock options and SARs, a limitation has been imposed upon the 
number of such awards which may be made under the 1997 Stock Plan.  
Specifically, no more than 250,000 (350,000 in the event of an option 
repricing) shares of Company Common Stock shall be subject to stock options 
and SARs that are granted annually under the 1997 Stock Plan to any one 
employee.  A maximum of 3,000,000 shares has been authorized for award under 
the 1997 Stock Plan plus shares which are not subject to grants under the 
1990 Stock Plan as of the effective date, and shares which become available 
because options under the 1990 Stock Plan are forfeited or terminate.

   OTHER PROVISIONS

   The 1997 Stock Plan contains customary provisions relating to adjustments 
for increases or decreases in the number and kind of Company securities. 
Furthermore, all awards under the 1997 Stock Plan vest fully and immediately 
upon death, disability or upon a change in control.  "Change in control" 
includes tender offers, mergers, sales of substantially all Company assets, 
change in a majority of the Company Board over a two-year period and the 
acquisition of more than 30% of the outstanding shares of Company Common 
Stock by a person who did not previously own 30% of such stock.

   The 1997 Stock Plan will expire ten years after its initial effective 
date, unless it is terminated before then by the Company's Board of Directors.

                                      -26-
<PAGE>

   The Company's Board of Directors may amend, suspend or terminate the 1997 
Stock Plan at any time without further action of the Company's stockholders 
except with respect to the accelerated vesting or share adjustment provisions 
and as required by applicable law.

FEDERAL INCOME TAX CONSEQUENCES

   The following discussion of the federal income tax consequences of the 
1997 Stock Plan as it relates to nonqualified stock options, incentive stock 
options and share awards is intended to be a summary of applicable federal 
law. State and local tax consequences may differ.

   OPTIONS

   Incentive stock options and nonqualified stock options are treated 
differently for federal income tax purposes. Incentive stock options are 
intended to comply with the requirements of Section 422 of the Code. 
Nonqualified stock options need not comply with such requirements.

   An optionee is generally not taxed on the grant or exercise of an 
incentive stock option. The difference between the exercise price and the 
fair market value of the shares on the exercise date will, however, be a 
preference item for purposes of the alternative minimum tax. If an optionee 
holds the shares acquired upon exercise of an incentive stock option for at 
least two years following grant and at least one year following exercise, the 
optionee's gain, if any, upon a subsequent disposition of such shares is a 
long-term capital gain (or loss). The measure of the gain is the difference 
between the proceeds received on disposition and the optionee's basis in the 
shares (which generally equals the exercise price). If an optionee disposes 
of stock acquired pursuant to exercise of an incentive stock option before 
satisfying the one and two-year holding periods described above, the optionee 
will recognize both ordinary income and capital gain (or loss) in the year of 
disposition. The amount of the ordinary income will be the lesser of (i) the 
amount realized on disposition less the optionee's adjusted basis in the 
stock (usually the option price) or (ii) the difference between the fair 
market value of the stock on the exercise date and the option price. The 
balance of the consideration received on such a disposition will be long-term 
capital gain if the stock had been held for at least one year following 
exercise of the incentive stock option.  The Company is not entitled to an 
income tax deduction on the grant or exercise of an incentive stock option or 
on the optionee's disposition of the shares after satisfying the holding 
period requirement described above.  If the holding periods are not 
satisfied, the Company will be entitled to a deduction in the year the 
optionee disposes of the shares, in an amount equal to the ordinary income 
recognized by the optionee.

   An optionee is not taxed on the grant of a nonqualified stock option. On 
exercise, however, the optionee recognizes ordinary income equal to the 
difference between the option price and the fair market value of the shares 
on the date of exercise.  The Company is entitled to an income tax deduction 
in the year of exercise in the amount recognized by the optionee as ordinary 
income. Any gain on subsequent disposition of the shares is a long-term 
capital gain if the shares are held for at least one year following exercise. 
 The Company does not receive a deduction for this gain.

   SHARE AWARDS

   If a participant is awarded or purchases shares, the amount by which the 
fair market value of the shares on the date of award or purchase exceeds the 
amount paid for the shares will be taxed to the participant as ordinary 
income. The Company will be entitled to a deduction in the same amount 
provided it makes all required withholdings on the compensation element of 
the sale or award. The participant's tax basis in the shares acquired is 
equal to the share's fair market value on the date of acquisition. Upon a 
subsequent sale of any shares, the participant will realize capital gain or 
loss (long-term or short-term, depending on whether the

                                      -27-
<PAGE>

shares were held for more than one year before the sale) in an amount equal 
to the difference between his or her basis in the shares and the sale price.

   If a participant is awarded or purchases shares that are subject to a 
vesting schedule, the participant is deemed to receive an amount of ordinary 
income equal to the excess of the fair market value of the shares at the time 
they vest over the amount (if any) paid for such shares by the participant.  
The Company is entitled to a deduction equal to the amount of the income 
recognized by the participant.

   Code Section 83(b) permits a participant to elect, within 30 days after 
the transfer of any shares subject to a vesting schedule to him or her, to be 
taxed at ordinary income rates on the excess of the fair market value of the 
shares at the time of the transfer over the amount (if any) paid by the 
participant for such shares. Withholding taxes apply at that time. If the 
participant makes a Section 83(b) election, any later appreciation in the 
value of the shares is not taxed as ordinary income, but instead is taxed as 
capital gain when the shares are sold or transferred.

   1997 TAX LAW

   The recently enacted 1997 Tax Law provides for lower capital gains rates 
if stock is held for eighteen months.  The 1997 Tax Law also provides for 
even lower applicable capital gains rates for stock acquired after December 
31, 2000 in certain circumstances if the stock is held for at least five 
years.

1997 STOCK PLAN BENEFITS

   The Committee has full discretion to determine the number, type and value 
of awards to be granted to key employees under the 1997 Stock Plan. 
Therefore, the benefits and amounts that will be received by each of the 
named executive officers, the executive officers as a group and all other key 
employees are not determinable.

  THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE ADOPTION OF THE AMENDMENT
    AND RESTATEMENT OF THE GENSIA SICOR INC. 1997 LONG-TERM INCENTIVE PLAN.

                                  PROPOSAL 4
                      APPROVAL OF THE CHAIRMAN'S OPTIONS

   Donald E. Panoz became the non-executive Chairman of the Board of the 
Company on February 28, 1997.  Prior to that time Mr. Panoz had not been a 
director or a consultant of Gensia Sicor or otherwise employed in any 
capacity by Gensia Sicor.  In order to induce Mr. Panoz to act as 
non-executive Chairman and provide certain other services to the Company, 
including, among other things, consulting on strategic planning and assisting 
with positioning Gensia Sicor in the financial community, the Company has, 
among other things, granted Mr. Panoz non-statutory stock options ("NSOs") to 
purchase 500,000 shares of the Company's Common Stock at an exercise price 
equal to $4.288 per share (the ten day average closing market price per share 
through February 24, 1997) (the "Chairman's Options").  The Chairman's 
Options were granted subject to the approval of the Company's stockholders 
because they were granted outside of Gensia Sicor's 1997 Long-Term Incentive 
Plan, which was approved by the Company's stockholders on February 26, 1997.  
For a description of other compensation payable to Mr. Panoz which is not 
subject to stockholder approval see "Compensation of Executive Officers and 
Directors - Compensation of Directors."  The Company believes that the 
granting of the Chairman's Options as well as the other compensation the 
Company has agreed to pay Mr. Panoz was necessary in order to attract a 
Chairman with the qualifications of Mr. Panoz.

   Of the 500,000 shares subject to the Chairman's Options, 200,000 shares 
are fully vested, and the remaining 300,000 shares will vest in increments of 
100,000 shares for each $100,000,000 increase in the

                                      -28-
<PAGE>

Company's market capitalization over $700,000,000 prior to February 28, 2000. 
Consequently Mr. Panoz will be fully vested in the event the Company's 
market capitalization exceeds $1.0 billion at any time prior to February 28, 
2000.  The Chairman's Options must be exercised by February 28, 2007.  On 
August 8, 1997, the closing price for the Company's Common Stock on the 
Nasdaq National Market was $4.50 per share and current market capitalization 
(based on shares of Common Stock outstanding as of July 31, 1997) was 
approximately $335,032,000.   No other director or officer has been granted 
any options with similar performance vesting requirements.

   The exercise price of the Chairman's Options is payable in cash.  The 
Chairman's Options also permit the optionee to pay the exercise price of an 
option by delivery (on a form prescribed by the Company) of an irrevocable 
direction to a securities broker approved by the Company to sell the 
optionee's shares and deliver all or a part of the sale proceeds to the 
Company in payment of all or part of the exercise price and any withholding 
taxes ("exercise/sale" directions) or by delivery of an irrevocable direction 
to pledge the optionee's shares to a securities broker or lender approved by 
the Company as security for a loan and to deliver all or part of the loan 
proceeds to the Company in payment of all or part of the exercise price and 
any withholding taxes ("exercise/pledge" directions).  The optionee may also 
exercise by transferring Shares already owned for six months by the optionee.

   In the event of a subdivision of the outstanding Common Stock or a 
combination or consolidation of the outstanding Common Stock (by 
reclassification or otherwise) into a lesser number of shares, or a similar 
occurrence, or declaration of a dividend payable in Common Stock or, if in an 
amount that has a material effect on the price of the shares, in cash, the 
Stock Option Committee will make adjustments in the number and/or the number 
of shares available under the Chairman's Options, as appropriate.

   In the event of a merger or other reorganization, any unexercised shares 
under the Chairman's Options will be subject to the agreement of merger or 
reorganization.  Such agreement may provide for the assumption of the 
unexercised portion by the surviving corporation or its parent, for 
continuation by the Company (if the Company is the surviving corporation), 
for payment of a cash settlement equal to the difference between the amount 
to be paid for one share under the agreement of merger or reorganization and 
the exercise price, or for the acceleration of exercisability followed by the 
cancellation of any portion of the option not exercised, in all cases without 
the optionee's consent.

FEDERAL INCOME TAX CONSEQUENCES OF OPTIONS

   Neither the optionee nor the Company will incur any federal tax 
consequences as a result of the grant of an option.  Upon exercising an NSO, 
the optionee must recognize ordinary income equal to the "spread" between the 
exercise price and the fair market value of Common Stock on the date of 
exercise; the Company will be entitled to a deduction for the same amount.

       THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE APPROVAL OF THE 
                              CHAIRMAN'S OPTIONS.

                                  PROPOSAL 5
                     RATIFICATION OF INDEPENDENT AUDITORS

   The Board of Directors, upon recommendation of the Audit Committee, has
appointed the firm of Ernst & Young LLP ("Ernst & Young") as the Company's
independent auditors for the fiscal year ended December 31, 1997, subject to
ratification by the stockholders.  Representatives of Ernst & Young are expected
to be present at the Company's Annual Meeting.  They will have an opportunity to
make a statement, if they desire to do so, and will be available to respond to
appropriate questions.

 THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR RATIFICATION OF THE APPOINTMENT 
                            OF ERNST & YOUNG LLP.

                                      -29-
<PAGE>

                             STOCKHOLDER PROPOSALS

   To be considered for inclusion in the proxy statement for presentation at
the Annual Meeting of Stockholders to be held in 1997 a stockholder proposal
must be received at the offices of the Company, 9360 Towne Centre Drive, San
Diego, CA 92121 not later than December 21, 1997.  The Company presently intends
to have its next Annual Meeting of Stockholders in May 1997.

            SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

   Under Section 16(a) under the Securities Exchange Act of 1934, as amended 
(the "Exchange Act"),  the Company's directors, executive officers, and any 
persons holding more than 10% of the Company's Common Stock are required to 
report their initial ownership of the Company's Common Stock and any 
subsequent changes in that ownership to the SEC.  Specific due dates for 
these reports have been established and the Company is required to identify 
in this Proxy Statement those persons who failed to timely file these 
reports.  All of the filing requirements were satisfied for 1996.

                                OTHER MATTERS

   The Board of Directors knows of no other business that will be presented 
at the Annual Meeting.  If any other business is properly brought before the 
Annual Meeting, it is intended that proxies in the enclosed form will be 
voted in accordance with the judgment of the persons voting the proxies.

   Any stockholder or stockholder's representative who, because of a 
disability, may need special assistance or accommodation to allow him or her 
to participate at the Annual Meeting may request reasonable assistance or 
accommodation from the Company by contacting Gensia Sicor Inc., 9360 Towne 
Centre Drive, San Diego, California, (619) 546-8300.  To provide the Company 
sufficient time to arrange for reasonable assistance or accommodation, please 
submit all requests by August 26, 1997.

   Whether you intend to be present at the Annual Meeting or not, we urge you 
to return your signed proxy promptly.

                                       By order of the Board of Directors.



                                       Wesley N. Fach
                                       Secretary




                                      -30-
<PAGE>

                                                                     EXHIBIT A

                               GENSIA SICOR INC.

               AMENDED AND RESTATED EMPLOYEE STOCK PURCHASE PLAN


   SECTION 1.     PURPOSE OF THE PLAN.

   The Plan was established effective as of July 1, 1992, subject to the 
approval of the Company's stockholders.  The purpose of the Plan is to 
provide Eligible Employees with an opportunity to increase their proprietary 
interest in the success of the Company by purchasing Stock from the Company 
on favorable terms and to pay for such purchases through payroll deductions.  
The Plan was restated and amended by the Board of Directors effective 
February 22, 1996 and June 20, 1997.  The Plan is intended to qualify under 
section 423 of the Internal Revenue Code of 1986, as amended.

   SECTION 2.     ADMINISTRATION OF THE PLAN.

   (a)  THE COMMITTEE.  The Plan shall be administered by the Committee.  The 
interpretation and construction by the Committee of any provision of the Plan 
or of any right to purchase Stock granted under the Plan shall be conclusive 
and binding on all persons.

   (b)  RULES AND FORMS.  The Committee may adopt such rules and forms under 
the Plan as it considers appropriate.

   SECTION 3.    ENROLLMENT AND PARTICIPATION.

   (a)  PARTICIPATION PERIODS.  While the Plan is in effect, there shall be 
two Participation Periods in each calendar year, consisting of the six-month 
periods commencing on each January 1 and July 1.

   (b)  ENROLLMENT.  Any individual who, on the date preceding the first day 
of a Participation Period, qualifies as an Eligible Employee may elect to 
become a Participant in the Plan for such Participation Period by executing 
the enrollment form prescribed for this purpose by the Committee.  The 
enrollment form shall be filed with the Company not later than the last 
working day prior to the commencement of such Participation Period.

   (c)  DURATION OF PARTICIPATION.  Once enrolled, a Participant shall 
continue to participate in the Plan for each succeeding Participation Period 
until he or she discontinues contributions, withdraws from the Plan or ceases 
to be an Eligible Employee.  A Participant who discontinues contributions 
under Section 4(d) or withdraws from the Plan under Section 5(a) may again 
become a Participant, if he or she then is an Eligible Employee, by following 
the procedure described in Subsection (b) above.

   SECTION 4.     EMPLOYEE CONTRIBUTIONS.

   (a)  FREQUENCY OF PAYROLL DEDUCTIONS.  A Participant may purchase shares 
of Stock under the Plan solely by means of payroll deductions.  Payroll 
deductions, as designated by the Participant pursuant to Subsection (b) 
below, shall commence with the first payday in the Participation Period and 
shall continue on each subsequent payday during participation in the Plan.

   (b)  AMOUNT OF PAYROLL DEDUCTIONS.  An Eligible Employee shall designate 
on the enrollment form the portion of his or her Compensation that he or she 
elects to have withheld for the purchase of Stock.  Such portion shall be a 
whole percentage of the Eligible Employee's Compensation, but not less than 
1% nor more than 12%.

                                      A-1
<PAGE>

   (c)  CHANGING WITHHOLDING RATE.  If a Participant wishes to change the 
rate of payroll withholding, he or she may do so by filing a new enrollment 
form with the Company not later than the last working day prior to the 
commencement of the Participation Period for which such change is to be 
effective.

   (d)  DISCONTINUING PAYROLL DEDUCTIONS.  If a Participant wishes to 
discontinue employee contributions entirely, he or she may do so by filing a 
new enrollment form at any time.  Payroll withholding shall cease as soon as 
reasonably practicable after such form has been received by the Company.

   SECTION 5.     WITHDRAWAL FROM THE PLAN.

   (a)  WITHDRAWAL.  A Participant may elect to withdraw from the Plan by 
filing the prescribed form with the Company at any time before the last day 
of a Participation Period.  As soon as reasonably practicable thereafter, 
payroll deductions shall cease and the entire amount credited to the 
Participant's Plan Account shall be refunded to him or her in cash, without 
interest.  No partial withdrawals shall be permitted.

   (b)  RE-ENROLLMENT AFTER WITHDRAWAL.  A former Participant who has 
withdrawn from the Plan shall not be a Participant until he or she re-enrolls 
for a subsequent Participation Period under Section 3(b).

   SECTION 6.     TERMINATION OF EMPLOYMENT AND DEATH.

   (a)  TERMINATION OF EMPLOYMENT.  Termination of employment as an Eligible 
Employee for any reason, including death, shall be treated as an automatic 
withdrawal from the Plan under Section 5(a).  (A transfer from one 
Participating Company to another shall not be treated as a termination of 
employment.)

   (b)  DEATH.  In the event of the Participant's death, the amount credited 
to his or her Plan Account shall be paid to a beneficiary designated by him 
or her for this purpose on the prescribed form or, if none, to the 
Participant's estate.

   SECTION 7.     PLAN ACCOUNTS AND PURCHASE OF SHARES.

   (a)  PLAN ACCOUNTS.  The Company shall maintain a Plan Account on its 
books in the name of each Participant.  As of each payday in a Participation 
Period, the amount deducted from the Participant's Compensation shall be 
credited to the Participant's Plan Account.  No interest shall be credited to 
Plan Accounts.

   (b)  PURCHASE PRICE.  The Purchase Price for each share of Stock shall be 
the lower of (i) 85% of the Fair Market Value of such share on the last 
trading day before the Participation Period commences or (ii) 85% of the Fair 
Market Value of such share on the last trading day in the Participation 
Period.

   (c)  NUMBER OF SHARES PURCHASED.  As of the last day of each Participation 
Period, each Participant shall be deemed to have elected to purchase the 
number of whole shares of Stock calculated in accordance with this Subsection 
(c), unless the Participant has previously elected to withdraw from the Plan 
in accordance with Section 5(a).  The amount then in the Participant's Plan 
Account shall be divided by the Purchase Price, and the number of whole 
shares that results shall be purchased from the Company with the funds in the 
Participant's Plan Account.  The foregoing notwithstanding, no Participant 
shall purchase more than a maximum of 1,000 shares of Stock with respect to 
any Participation Period nor shares of Stock in excess of the amounts set 
forth in Sections 8 and 12(a).

   (d)  AVAILABLE SHARES INSUFFICIENT.  In the event that the aggregate 
number of shares that all Participants elect to purchase during a 
Participation Period exceeds the maximum number of shares remaining available 
for issuance under Section 12(a), then the number of shares to which each 
Participant is entitled shall be determined by multiplying the number of 
shares available for issuance by a fraction, the numerator of which is the 
number of shares that such Participant has elected to purchase and the 
denominator of which is the number of shares that all Participants have 
elected to purchase.

                                      A-2
<PAGE>

   (e)  ISSUANCE OF STOCK.  Certificates representing the number of shares of 
Stock purchased shall be issued as soon as reasonably practicable after the 
close of the Participation Period.  Shares may be registered in the name of 
the Participant or jointly in the name of the Participant and his or her 
spouse as joint tenants with right of survivorship or as community property.

   (f)  UNUSED CASH BALANCES.  Any amount remaining in the Participant's Plan 
Account that represents the Purchase Price for a fractional share shall be 
carried over in the Participant's Plan Account to the next Participation 
Period. Any amount remaining in the Participant's Plan Account that 
represents the Purchase Price for whole shares which could not be purchased 
under Subsection (c) above or Section 12(a) shall be refunded to the 
Participant in cash, without interest.

   SECTION 8.     LIMITATIONS ON STOCK OWNERSHIP.

   Any other provision of the Plan notwithstanding, no Participant shall be 
granted a right to purchase Stock under the Plan if:

        (a)  Such Participant, immediately after his or her election to
   purchase such Stock, would own stock possessing more than 5% of the total
   combined voting power or value of all classes of stock of the Company or
   any parent or Subsidiary of the Company; or

        (b)  Under the terms of the Plan, such Participant's rights to
   purchase stock under this and all other qualified employee stock purchase
   plans of the Company or any parent or Subsidiary of the Company would
   accrue at a rate that exceeds $25,000 of the fair market value of such
   stock (determined at the time when such right is granted) for each calendar
   year for which such right or option is outstanding at any time.

Ownership of stock shall be determined after applying the attribution rules 
of section 424(d) of the Internal Revenue Code of 1986, as amended.  For 
purposes of this Section 8, each Participant shall be considered to own any 
stock that he or she has a right or option to purchase under this or any 
other plan, and each Participant shall be considered to have the right to 
purchase 1,000 shares of Stock under this Plan with respect to each 
Participation Period.

   SECTION 9.     RIGHTS NOT TRANSFERABLE.

   The rights of any Participant under the Plan, or any Participant's 
interest in any Stock or moneys to which he or she may be entitled under the 
Plan, shall not be transferable by voluntary or involuntary assignment or by 
operation of law, or in any other manner other than by will or the laws of 
descent and distribution.  If a Participant in any manner attempts to 
transfer, assign or otherwise encumber his or her rights or interest under 
the Plan, other than by will or the laws of descent and distribution, then 
such act shall be treated as an election by the Participant to withdraw from 
the Plan under Section 5(a).

   SECTION 10.    NO RIGHTS AS AN EMPLOYEE.

   Nothing in the Plan shall be construed to give any person the right to 
remain in the employ of a Participating Company.  Each Participating Company 
reserves the right to terminate the employment of any person at any time, 
with or without cause.

   SECTION 11.   NO RIGHTS AS A STOCKHOLDER.

   A Participant shall have no rights as a stockholder with respect to any 
shares that he or she has purchased, or may have a right to purchase, under 
the Plan until the date of issuance of a stock certificate for such shares.

                                      A-3
<PAGE>

   SECTION 12.   STOCK OFFERED UNDER THE PLAN.

   (a)  AUTHORIZED SHARES.  The aggregate number of shares of Stock available 
for purchase under the Plan shall be 500,000, subject to adjustment pursuant 
to this Section 12.

   (b)  ANTI-DILUTION ADJUSTMENTS.  The aggregate number of shares of Stock 
offered under the Plan, the 1,000-share limitation described in Section 7(c) 
and the price of shares that any Participant has elected to purchase shall be 
adjusted proportionately by the Committee for any increase or decrease in the 
number of outstanding shares of Stock resulting from a subdivision or 
consolidation of shares, the payment of a stock dividend, any other increase 
or decrease in such shares effected without receipt or payment of 
consideration by the Company or the distribution of the shares of a 
Subsidiary to the Company's stockholders.

   (c)  REORGANIZATIONS.  In the event of a dissolution or liquidation of the 
Company, or a merger or consolidation to which the Company is a constituent 
corporation, the Plan shall terminate unless the plan of merger, 
consolidation or reorganization provides otherwise, and all amounts that have 
been withheld but not yet applied to purchase Stock hereunder shall be 
refunded, without interest.  The Plan shall in no event be construed to 
restrict in any way the Company's right to undertake a dissolution, 
liquidation, merger, consolidation or other reorganization.

   SECTION 13.   AMENDMENT OR DISCONTINUANCE.

   The Board of Directors shall have the right to amend, suspend or terminate 
the Plan at any time and without notice; provided that no Participant's 
existing rights are adversely affected thereby and that, except as provided 
in Section 12, any increase in the aggregate number of shares of Stock to be 
issued under the Plan shall be subject to approval by a vote of the 
stockholders of the Company.

   SECTION 14.    STOCKHOLDER APPROVAL.

   (a)  STOCKHOLDER APPROVAL REQUIRED.  The Plan and any rights to purchase 
shares hereunder shall be void if the Plan is not approved by the Company's 
stockholders on or before the earlier of (i) the date of the 1996 annual 
meeting of the Company's stockholders or (ii) the date 12 months after the 
adoption of the Plan by the Board of Directors.  Until stockholder approval 
is obtained, all shares purchased under the Plan shall be held in escrow by 
the Company or its designee as agent for the Participants and spouses who own 
such shares and shall not be transferable or assignable.

   (b)  STOCKHOLDER APPROVAL NOT OBTAINED.  In the event that stockholder 
approval is not obtained on or before the prescribed date, the Plan shall 
terminate, all shares then held in escrow shall be repurchased by the Company 
for an amount equal to the Purchase Price paid by the Participants, and all 
amounts then held in Plan Accounts shall be refunded to the Participants 
without interest.

   SECTION 15.    DEFINITIONS.

   (a)  "Board of Directors" means the Board of Directors of the Company, as 
constituted from time to time.

   (b)  "Committee" means the Stock Option Committee of the Board of 
Directors.

   (c)  "Company" means Gensia Sicor Inc., a Delaware corporation.

   (d)  "Compensation" means the base compensation paid in cash to a 
Participant by a Participating Company, including salaries and wages, but 
excluding bonuses, incentive compensation, commissions, overtime pay, moving 
or relocation allowances, car allowances, imputed income attributable to 
cars, taxable fringe benefits and similar items, all as determined by the 
Committee.

                                      A-4
<PAGE>

   (e)  "Eligible Employee" means any employee of a Participating Company 
(i) whose customary employment is for more than five months per calendar year 
and for more than 20 hours per week and (ii) who has been an employee of a 
Participating Company for not less than three consecutive months.

   (f)  "Fair Market Value" shall mean the market price of Stock, determined 
by the Committee as follows:

        (i) If the Stock was traded over-the-counter on the date in question
   but was not traded on the Nasdaq system or the Nasdaq National Market
   System, then the Fair Market Value shall be equal to the mean between the
   last reported representative bid and asked prices quoted for such date by
   the principal automated inter-dealer quotation system on which the Stock is
   quoted or, if the Stock is not quoted on any such system, by the "Pink
   Sheets" published by the National Quotation Bureau, Inc.;

       (ii) If the Stock was traded over-the-counter on the date in question
   and was traded on the Nasdaq system or the Nasdaq National Market System,
   then the Fair Market Value shall be equal to the last-transaction price
   quoted for such date by the Nasdaq system or the Nasdaq National Market
   System;

      (iii) If the Stock was traded on a stock exchange on the date in
   question, then the Fair Market Value shall be equal to the closing price
   reported by the applicable composite transactions report for such date; and

       (iv) If none of the foregoing provisions is applicable, then the Fair
   Market Value shall be determined by the Committee in good faith on such
   basis as it deems appropriate.

Whenever possible, the determination of Fair Market Value by the Committee 
shall be based on the prices reported in the Western Edition of THE WALL 
STREET JOURNAL.  Such determination shall be conclusive and binding on all 
persons.

   (g)  "Participant" means an Eligible Employee who elects to participate 
in the Plan, as provided in Section 3(b).

   (h)  "Participating Company" means the Company and each present or future 
Subsidiary, except Subsidiaries excluded by the Committee.

   (i)  "Participation Period" means a period during which contributions may 
be made toward the purchase of Stock under the Plan, as determined pursuant 
to Section 3(a).

   (j)  "Plan" means this Gensia Sicor Inc. Employee Stock Purchase Plan, as 
amended from time to time.

   (k)  "Plan Account" means the account established for each Participant 
pursuant to Section 6(a).

   (l)  "Purchase Price" means the price at which Participants may purchase 
Stock under the Plan, as determined pursuant to Section 7(b).

   (m)  "Stock" means the Common Stock of the Company.

   (n)  "Subsidiary" means a corporation, 50% or more of the total combined 
voting power of all classes of stock of which is owned by the Company or by 
another Subsidiary.

                                      A-5
<PAGE>

   SECTION 16.   EXECUTION.

   To record the amendment and restatement of the Plan by the Board of 
Directors on June 20, 1997, the Company has caused its duly authorized 
officer to affix the corporate name and seal hereto.

                                       GENSIA SICOR INC.




                                       By  /s/ David F. Hale
                                          -------------------------------
                                          President



                                      A-6
<PAGE>

                                                                     EXHIBIT B

                               GENSIA SICOR INC.

                         1997 LONG-TERM INCENTIVE PLAN

   1.   INTRODUCTION AND PURPOSE OF THE PLAN.

   The Plan was adopted by the Board on November 12, 1996, and approved by 
the Company's stockholders February 26, 1997.  The Plan is effective as of 
February 26, 1997.  The Plan replaces the Amended and Restated 1990 Stock 
Plan of Gensia, Inc. (the "1990 Stock Plan"). The Plan was amended by the 
Board on June 20, 1997.

   The purpose of the Plan is to promote the interests of Gensia Sicor Inc., 
and its stockholders by encouraging officers and Key Employees to acquire 
stock or increase their proprietary interest in the Company.  By thus 
providing the opportunity to acquire Company stock and receive incentive 
payments, the Company seeks to attract and retain such Key Employees upon 
whose judgment, initiative, and leadership the success of the Company largely 
depends.

   The Plan shall be governed by, and construed in accordance with, the laws 
of the State of California.

   2.   DEFINITIONS.

   Whenever the following terms are used in this Plan, they will have the 
meanings specified below unless the context clearly indicates the contrary.

   (a)  "Board of Directors" or "Board" means the Board of Directors of the 
Company, as constituted from time to time.

   (b)  "Change-in-Control" occurs in the following instances (1) a tender or 
exchange for all or part of Company Common Stock (except an offer by the 
Company itself); (2) Company stockholder approval of a merger in which the 
Company does not survive as an independent and publicly owned corporation 
(except a merger which leaves Company stockholders with substantially the 
same ownership in the new corporation); (3) Company stockholder approval of a 
consolidation or sale, exchange or other disposition of all, or substantially 
all, of the Company's assets; (4) change in the composition of the Board over 
a two consecutive year period so that individuals who were directors at the 
beginning of that period no longer constitute a majority of the Board (unless 
the election or nomination of each new director was approved by at least 
two-thirds of the directors who had been directors at the beginning of the 
period and who were still in office at the time of the election or 
nomination); or (5) the acquisition of sufficient Common Shares such that a 
person who previously did not own at least 30% of Company Common Shares, 
thereafter owns at least 30% (except an acquisition by the Company itself, by 
a subsidiary of the Company or a benefit plan maintained by the Company).

   (c)  "Code" means the Internal Revenue Code of 1986, as amended.

   (d)  "Committee" means the committee appointed to administer the Plan 
pursuant to Section 4.

   (e)  "Company" means Gensia Sicor Inc., a Delaware corporation.

   (f)  "Common Shares" or "Common Stock" means the common shares of Gensia 
Sicor Inc., and any class of common shares into which such common shares may 
hereafter be converted.

   (g)  "Dividend Equivalent" means the additional amount of Common Stock 
issued in connection with an Option, as described in Section 14.

                                      B-1
<PAGE>

   (h)  "Eligible Person" means a Key Employee eligible to receive an 
Incentive Award.

   (i)  "Exchange Act" means the Securities and Exchange Act of 1934, as 
amended.

   (j)  "Fair Market Value" means the market price of Common Shares, 
determined by the Committee as follows:

       (i) If the Common Shares were traded over-the-counter on the date in
   question but were not traded on the Nasdaq system or the Nasdaq National
   Market System, then the Fair Market Value shall be equal to the mean
   between the last reported representative bid and asked prices quoted for
   such date by the principal automated inter-dealer quotation system on which
   the Common Shares are quoted or, if the Common Shares are not quoted on any
   such system, by the "Pink Sheets" published by the National Quotation
   Bureau, Inc.;

      (ii) If the Common Shares were traded over-the-counter on the date in
   question and were traded on the Nasdaq system or the Nasdaq National Market
   System, then the Fair Market Value shall be equal to the last-transaction
   price quoted for such date by the Nasdaq system or the Nasdaq National
   Market System;

     (iii) If the Common Shares were traded on a stock exchange on the date
   in question, then the Fair Market Value shall be equal to the closing price
   reported by the applicable composite transactions report for such date; and

      (iv) If none of the foregoing provisions is applicable, then the Fair
   Market Value shall be determined by the Committee in good faith on such
   basis as it deems appropriate.

        In all cases, the determination of Fair Market Value by the Committee 
shall be conclusive and binding on all persons.

   (k)  "Holder" means a person, estate, trust or entity holding an Incentive 
Award.

   (l)  "Incentive Award" means any Nonqualified Stock Option, Incentive 
Stock Option, Common Stock, Restricted Stock, Stock Appreciation Right, 
Dividend Equivalent, Stock Payment or Performance Award granted under the 
Plan.

   (m)  "Incentive Stock Option" means an Option as defined under Section 422 
of the Code, including an Incentive Stock Option granted pursuant to Section 
8 of the Plan.

   (n) "Key Employee" shall mean (i) any individual who is a common-law 
employee of the Company or of a Subsidiary, (ii) a member of the Board of 
Directors, including (without limitation) an Outside Director, or an 
affiliate of a member of the Board of Directors, (iii) a member of the board 
of directors of a Subsidiary and (iv) an independent contractor who performs 
services for the Company or a Subsidiary.  Service as a member of the Board 
of Directors, a member of the board of directors of a Subsidiary or as an 
independent contractor shall be considered employment for all purposes of the 
Plan, except as provided in Sections 5(b) and 6.

   (o)  "Nonqualified Stock Option" means an Option other than an Incentive 
Stock Option granted pursuant to Section 8 of the Plan.

   (p)  "Option" means either a Nonqualified Stock Option or Incentive Stock 
Option.

   (q)  "Outside Director" shall mean a member of the Board of Directors who 
is not a common-law employee of the Company or a Subsidiary.

                                      B-2
<PAGE>

   (r)  "Performance Award" means an award whose value may be linked to stock 
value, book value, or other specific performance criteria which may be set by 
the Board of Directors, but which is paid in cash, stock, or a combination of 
both.

   (s)  "Plan" means the 1997 Long-Term Incentive Plan, which may be amended 
from time to time.

   (t)  "Restricted Stock" means Company stock sold or granted to an Eligible 
Person, which is nontransferable and subject to substantial risk of 
forfeiture until restrictions lapse.

   (u)  "Stock Appreciation Right" or "Right" means a right granted pursuant 
to Section 11 of the Plan to receive a number of shares of Common Stock or, 
in the discretion of the Committee, an amount of cash or a combination of 
shares and cash, based on the increase in the Fair Market Value or book value 
of the shares subject to the right.

   (v)  "Stock Payment" means a payment in shares of the Common Stock to 
replace all or any portion of the compensation (other than base salary) that 
would otherwise become payable to an employee in cash.

   (w)  "Subsidiary" means any corporation (other than the Company) in an 
unbroken chain of corporations beginning with the Company, if each of the 
corporations other than the last corporation in the unbroken chain owns stock 
possessing 50% or more of the total combined voting power of all classes of 
stock in one of the other corporations in such chain.  A corporation that 
attains the status of a Subsidiary on a date after the adoption of the Plan 
shall be considered a Subsidiary commencing as of such date.

   (x)  "Total and Permanent Disability" means that the Holder is unable to 
engage in any substantial gainful activity by reason of any medically 
determinable physical or mental impairment which can be expected to result in 
death or which has lasted, or can be expected to last, for a continuous 
period of not less than one year.

   3.   SHARES OF COMMON STOCK SUBJECT TO THE PLAN.

   (a)  Subject to the provisions of Sections 3(c) and 15 of the Plan, the 
aggregate number of shares of Common Stock that may be issued or transferred 
pursuant to Incentive Awards or covered by Stock Appreciation Rights 
unrelated to Options under the Plan shall not exceed 3,000,000, and the 
number of shares that may be issued or transferred during any 12-month period 
to any Eligible Person pursuant to an Incentive Award or a Stock Appreciation 
Right unrelated to an Option shall not exceed 250,000 (or 350,000 in the 
event of an Option repricing during that 12-month period).  Additionally, the 
number of shares of Common Stock available under the Company's 1990 Stock 
Plan (whether by forfeiture, termination or nongrant) shall also become 
available under this Plan.

   (b)  The shares to be delivered under the Plan will be made available, at 
the discretion of the Board of Directors or the Committee, either from 
authorized but unissued shares of Common Stock or from previously issued 
shares of Common Stock reacquired by the Company, including shares purchased 
on the open market.

   (c)  If Incentive Awards are forfeited or if Incentive Awards terminate 
for any other reason before being exercised, then such Incentive Awards shall 
again become available for award under the Plan. If Stock Appreciation Rights 
are exercised, then only the number of Common Shares (if any) actually issued 
in settlement of such Stock Appreciation Rights shall reduce the number of 
Common Shares available under Section 3(a) and the balance shall again become 
available for award under the Plan.  If Restricted Stock is forfeited, then 
such Restricted Stock shall again become available for award under the Plan.

                                      B-3
<PAGE>

   4.   ADMINISTRATION OF THE PLAN.

   (a) The Plan shall be administered by the Committee.  The Committee shall 
consist exclusively of directors of the Company, who shall be appointed by 
the Board.  In addition, the composition of the Committee shall satisfy:

       (1)  Such requirements, if any, as the Securities and Exchange
   Commission may establish for administrators acting under plans intended to
   qualify for exemption under Rule 16b-3 (or its successor) under the
   Exchange Act; and

       (2)  Such requirements as the Internal Revenue Service may establish
   for outside directors acting under plans intended to qualify for exemption
   under Section 162(m) of the Code.

The Board shall act on its own behalf with respect to the grant or amendment 
of Incentive Awards to Outside Directors and may also appoint separate 
committees of the Board, each composed of one or more officers of the Company 
who need not be directors of the Company, to administer the Plan with respect 
to Key Employees who are not "covered employees" under Section 162(m) of the 
Code and who are not required to report pursuant to Section 16(a) of the 
Exchange Act.

   (b)  The Committee has and may exercise such powers and authority as may 
be necessary or appropriate for the Committee to carry out its functions as 
described in the Plan.  The Committee has authority in its discretion to 
determine the Eligible Persons to whom, and the time or times at which, 
Incentive Awards may be granted and the number of shares or Rights subject to 
each award.  Subject to the express provisions of the Plan, the Committee 
also has authority to interpret the Plan, and to determine the terms and 
provisions of the respective Incentive Award agreements (which need not be 
identical) and to make all other determinations necessary or advisable for 
Plan administration. The Committee has authority to prescribe, amend, and 
rescind rules and regulations relating to the Plan.  All interpretations, 
determinations, and actions by the Committee will be final, conclusive, and 
binding upon all parties.

   (c)  No member of the Board of Directors or the Committee will be liable 
for any action or determination made in good faith by the Committee with 
respect to the Plan or any Incentive and Performance Award under it.

   5.   ELIGIBILITY AND DATE OF GRANT.

   The date of grant of an Incentive Award will be the date the Committee 
takes the necessary action to approve the grant; provided, however, that if 
the minutes or appropriate resolutions of the Committee provide that an 
Incentive Award is to be granted as of a date in the future, the date of 
grant will be such future date.

   6.   OUTSIDE DIRECTOR PARTICIPATION.

   Outside Directors shall receive Option grants under the Plan as described 
below:

   (a)  Upon the conclusion of each regular annual meeting of the Company's 
stockholders, each incumbent Outside Director who will continue serving as a 
member of the Board thereafter may receive a grant of a Nonstatutory Option 
for such number of Common Shares (subject to adjustment under Section 15 and 
prorated for partial year service) as the Board shall determine in its sole 
discretion.

   (b)  New Outside Directors shall receive a one-time grant of a 
Nonstatutory Option for a number of Common Shares as determined in the sole 
discretion of the Board; provided, however, that such grant shall not be made 
in any calendar year in which the same individual receives an Option under 
(a) above.  Such Option, if any, shall be granted on the date when such 
Outside Director first joins the Board of Directors of the Company or the 
board of directors of a Subsidiary.

                                      B-4
<PAGE>

   (c) Total grants under this Section 6 (less forfeitures) shall not exceed 
15% of the maximum number of Common Shares available for grant under Section 
3(a) of the Plan (subject to adjustment under Section 15).

   7.   NONQUALIFIED STOCK OPTIONS.

   The Committee may approve the grant of Nonqualified Stock Options to 
Eligible Persons, subject to the following terms and conditions:

       (a)  The purchase price of Common Stock under each Nonqualified Stock
   Option may not be less than eighty-five percent (85%) of the Fair Market
   Value of the Common Stock on the date the Nonqualified Stock Option is
   granted.

       (b)  No Nonqualified Stock Option may be exercised after ten (10)
   years from the date of grant.

       (c)  No fractional shares will be issued pursuant to the exercise of a
   Nonqualified Stock Option nor will any cash payment be made in lieu of
   fractional shares.

   8.   INCENTIVE STOCK OPTIONS.

   The Committee may approve the grant of Incentive Stock Options to Eligible
Persons, subject to the following terms and conditions:

       (a)  The purchase price of each share of Common Stock under an
   Incentive Stock Option will be at least equal to the Fair Market Value of a
   share of the Common Stock on the date of grant; provided, however, that if
   an employee, at the time an Incentive Stock Option is granted, owns stock
   representing more than ten percent (10%) of the total combined voting power
   of all classes of stock of the Company (as defined in Section 424 of the
   Code), then the Exercise Price of each share of Common Stock subject to
   such Incentive Stock Option shall be at least one hundred and ten percent
   (110%) of the Fair Market Value of such share of Common Stock, as
   determined in the manner stated above.

       (b)  No Incentive Stock Option may be exercised after ten (10) years
   from the date of grant; provided, however, that if any employee, at the
   time an Incentive Stock Option is granted to him, owns stock representing
   more than ten percent (10%) of the total combined voting power of all
   classes of stock of the Company (as defined in Section 424 of the Code),
   the Incentive Stock Option granted shall not be exercisable after the
   expiration of five (5) years from the date of grant.

       (c)  No fractional shares will be issued pursuant to the exercise of
   an Incentive Stock Option nor will any cash payment be made in lieu of
   fractional shares.

   9.   OPTION RULES.

   The purchase price under each Option may be paid in cash, cash equivalents 
or notes acceptable to the Committee, by arrangement with a broker which is 
acceptable to the Committee where payment of the Option price is made 
pursuant to an irrevocable direction to the broker to deliver all or part of 
the proceeds from the sale of the Option shares to the Company, by the 
surrender of shares of Common Stock owned by the Holder exercising the Option 
and having a Fair Market Value on the date of exercise equal to the purchase 
price or in any combination of the foregoing.  Each Option granted to an 
Eligible Person shall be exercisable in such manner and at such times as the 
Committee shall determine. The Committee may modify, accelerate the 
exercisability of, extend or assume outstanding Options or may accept the 
cancellation of outstanding Options (whether granted by the Company or by 
another issuer) in return for the grant of new Options for the same or a 
different number of shares and at the same or a different purchase price.  
The foregoing notwithstanding, no modification of an Option shall, without 
the consent of the Holder, alter or impair his or her rights or obligations 
under such Option.

                                      B-5
<PAGE>

   10.  RESTRICTED STOCK.

   The Committee may approve the grant of Restricted Stock related or 
unrelated to Nonqualified Stock Options or Stock Appreciation Rights to 
Eligible Persons, subject to the following terms and conditions:

   (a)  The Committee in its discretion will determine the purchase price.

   (b)  All shares of Restricted Stock sold or granted pursuant to the Plan 
(including any shares of Restricted Stock received by the Holder as a result 
of stock dividends, stock splits, or any other forms of capitalization) will 
be subject to the following restrictions:

       (i)  The shares may not be sold, transferred, or otherwise alienated
   or hypothecated until the restrictions are removed or expire.

      (ii)  The Committee may require the Holder to enter into an escrow
   agreement providing that the certificates representing Restricted Stock
   sold or granted pursuant to the Plan will remain in the physical custody of
   an escrow holder until all restrictions are removed or expire.

     (iii)  Each certificate representing Restricted Stock sold or granted
   pursuant to the Plan will bear a legend making appropriate reference to the
   restrictions imposed on the Restricted Stock.

      (iv)  The Committee may impose restrictions on any shares sold pursuant
   to the Plan as it may deem advisable, including, without limitation,
   restrictions designed to facilitate exemption from or compliance with the
   Securities Exchange Act of 1934, as amended, with requirements of any stock
   exchange upon which such shares or shares of the same class are then listed
   and with any blue sky or other securities laws applicable to such shares.

   (c)  The restrictions imposed under subparagraph (b) above upon Restricted 
Stock will lapse in accordance with a schedule or other conditions as 
determined by the Committee, subject to the provisions of Section 17, 
subparagraph (d).

   (d)  Subject to the provisions of subparagraph (b) above and Section 17, 
subparagraph (d), the Holder will have all rights of a stockholder with 
respect to the Restricted Stock granted or sold, including the right to vote 
the shares and receive all dividends and other distributions paid or made 
with respect thereto.

   (e)  Notwithstanding the provisions of subparagraph (b) above and Section 
17, subparagraph (d), Restricted Stock granted or sold may be held by the 
trustee of a revocable inter vivos trust (or other trust if such transfer 
associated therewith does not cause income to be recognized pursuant to Code 
Section 83 and if the trust takes subject to the forfeiture provisions of the 
Restricted Stock), approved by the Company, established in whole or in part 
by the Holder and/or the Holder's spouse.  So long as the Holder is still an 
employee, transfer to such trust shall not violate the provisions of 
subparagraph (b) above and ownership by such trust shall not invoke any right 
or obligation of the Company under Section 17, subparagraph (d).

   11.  STOCK APPRECIATION RIGHTS.

   The Committee may approve the grant of Rights related or unrelated to 
Options to Eligible Persons, subject to the following terms and conditions:

   (a)  A Stock Appreciation Right may be granted

         (i)  at any time if unrelated to an Option;

        (ii)  either at the time of grant, or at any time thereafter during 
    the Option term if related to a Nonqualified Stock Option; or

                                      B-6
<PAGE>

       (iii)  only at the time of grant if related to an Incentive Stock
    Option.

   (b)  A Stock Appreciation Right granted in connection with an Option will 
entitle the Holder of the related Option, upon exercise of the Stock 
Appreciation Right, to surrender such Option, or any portion thereof to the 
extent unexercised, with respect to the number of shares as to which such 
Stock Appreciation Right is exercised, and to receive payment of an amount 
computed pursuant to Section 11(d).  Such Option will, to the extent 
surrendered, then cease to be exercisable.

   (c)  Subject to Section 11(g), a Stock Appreciation Right granted in 
connection with an Option hereunder will be exercisable at such time or times 
as the Committee in its discretion may determine, and only to the extent that 
a related Option is exercisable, and will not be transferable except to the 
extent that such related Option is exercisable.

   (d)  Upon the exercise of a Stock Appreciation Right related to an Option, 
the Holder will be entitled to receive payment of an amount determined by 
multiplying:

        (i)  The difference obtained by subtracting the purchase price of a
    share of Common Stock specified in the related Option from the Fair Market
    Value of a share of Common Stock on the date of exercise of such Stock
    Appreciation Right, by

       (ii)  The number of shares as to which such Stock Appreciation Right has
    been exercised.

   (e)  The Committee may grant Stock Appreciation Rights unrelated to 
Options to Eligible Persons which will be exercisable at such times as the 
Committee shall determine.  Section 11(d) shall be used to determine the 
amount payable at exercise under such Stock Appreciation Right if Fair Market 
Value is used, except that Fair Market Value shall not be used if the 
Committee specifies in the grant of the Right that book value or other 
measure as deemed appropriate by the Committee is to be used, and the initial 
share value specified in the award shall be used in lieu of "price of a share 
of Common Stock specified in the related Option," as provided in Section 
11(d).

   (f)  Payment of the amount determined under Section 11(d) or (e) may be 
made solely in whole shares of Common Stock in a number determined at their 
Fair Market Value on the date of exercise of the Stock Appreciation Right or 
alternatively, at the sole discretion of the Committee, solely in cash or in 
a combination of cash and shares as the Committee deems advisable.  If the 
Committee decides to make full payment in shares of Common Stock, and the 
amount payable results in a fractional share, payment for the fractional 
share will be made in cash.

   (g)  The Committee shall, at the time a Stock Appreciation Right is 
granted, impose such conditions on the exercise of the Stock Appreciation 
Right as may be required to satisfy the requirements of Rule 16b-3 under the 
Securities Exchange Act of 1934 (or any other comparable provisions in effect 
at the time or times in question).  In addition, a Stock Appreciation Right 
granted under the Plan may provide that it will be exercisable only in the 
event of a Change-in-Control.

   12.  PERFORMANCE AWARDS.

   The Committee may approve Performance Awards to Eligible Persons.  Such 
awards may be based on Common Stock performance over a period determined in 
advance by the Committee or any other measures as determined appropriate by 
the Committee.  Payment will be in cash unless replaced by a Stock Payment in 
full or in part as determined by the Committee.

                                      B-7
<PAGE>

   13.  STOCK PAYMENT.

   The Committee may approve Stock Payments of Common Stock to Eligible 
Persons for all or any portion of the compensation (other than base salary) 
that would otherwise become payable to an employee in cash.

   14.  DIVIDEND EQUIVALENTS.

   A Holder may also be granted at no additional cost "Dividend Equivalents" 
based on the dividends declared on the Common Stock on record dates during 
the period between the date an Option is granted and the date such Option is 
exercised, or such other equivalent period, as determined by the Committee. 
Such Dividend Equivalents shall be converted to additional shares or cash by 
such formula as may be determined by the Committee.

   Dividend Equivalents shall be computed, as of each dividend record date, 
both with respect to the number of shares under the Option and with respect 
to the number of Dividend Equivalent shares previously earned by the Holder 
(or his successor in interest) and not issued during the period prior to the 
dividend record date.

   15.  ADJUSTMENT PROVISIONS.

   (a)  Subject to Section 15(b), if the outstanding shares of Common Stock 
are increased, decreased, or exchanged for a different number or kind of 
shares or other securities, or if additional shares or new or different 
shares or other securities are distributed with respect to such shares of 
Common Stock or other securities, through merger, consolidation, sale of all 
or substantially all of the property of the Company, reorganization, 
recapitalization, reclassification, stock dividend, stock split, reverse 
stock split or other distribution with respect to such shares of Common 
Stock, or other securities, an appropriate and proportionate adjustment shall 
be made in (i) the maximum number and kind of shares provided in Section 3 of 
the Plan, (ii) the number and kind of shares or other securities subject to 
the then outstanding Incentive Awards, and (iii) the price for each share or 
other unit of any other securities subject to then outstanding Incentive 
Awards without change in the aggregate purchase price or value as to which 
Incentive Awards remain exercisable or subject to restrictions.

   (b)  In addition, upon a Change-in-Control, all Options, Stock 
Appreciation Rights, and Performance Awards then outstanding under the Plan 
will be fully vested and exercisable and all restrictions on Restricted Stock 
will immediately cease.  The Committee or any agreement of merger or 
reorganization may offer the Holder the right to exchange such vested 
Incentive Awards for fully vested and equivalent value awards under a 
successor plan.

   16.  GENERAL PROVISIONS.

   (a)  With respect to any shares of Common Stock issued or transferred 
under any provision of the Plan, such shares may be issued or transferred 
subject to such conditions, in addition to those specifically provided in the 
Plan, as the Committee may direct.

   (b)  Nothing in the Plan or in any instrument executed pursuant to the 
Plan will confer upon any Holder any right to continue in the employ of the 
Company or any of its Subsidiaries or affect the right of the Company to 
terminate the employment of any Holder at any time and for any reason.

   (c)  No shares of Common Stock will be issued or transferred pursuant to 
an Incentive Award unless and until all then applicable requirements imposed 
by federal and state securities and other laws, rules, and regulations and by 
any regulatory agencies having jurisdiction, and by any stock exchanges upon 
which the Common Stock may be listed, have been fully met.  As a condition 
precedent to the issue of shares pursuant to

                                      B-8
<PAGE>

the grant or exercise of an Incentive Award, the Company may require the 
Holder to take any reasonable action to meet such requirements.

   (d)  No Holder (individually or as a member of a group) and no beneficiary 
or other person claiming under or through such Holder will have any right, 
title, or interest in or to any shares of Common Stock allocated or reserved 
under the Plan or subject to any Incentive Award except as to such shares of 
Common Stock, if any, that have been issued or transferred to such Holder.

   (e)  The Company may make such provisions as it deems appropriate to 
withhold any taxes which it determines it is required to withhold in 
connection with any Incentive or Performance Award.

   (f)  No Incentive Award and no right under the Plan, contingent or 
otherwise, will be assignable or subject to any encumbrance, pledge (other 
than a pledge to secure a loan from the Company), or charge of any nature 
except that, under such rules and regulations as the Company may establish 
pursuant to the terms of the Plan, a beneficiary may be designated with 
respect to an Incentive Award in the event of death of a Holder of such 
Incentive Award.  If such beneficiary is the executor or administrator of the 
estate of the Holder of such Incentive Award, any rights with respect to such 
Incentive Award may be transferred to the person or persons or entity 
(including a trust) entitled thereto under the will of the Holder of such 
Incentive Award, or, in the case of intestacy, under the laws relating to 
intestacy.  Except as determined by the Committee, no Incentive Award shall 
be transferable by any Eligible Person other than by will or the laws of 
descent and distribution or pursuant to a qualified domestic relations order. 
 In considering transferability of an Incentive Award, the Committee may also 
consider the registration limitation of SEC Form S-8 and on that basis may in 
its discretion determine whether to prohibit transferability, permit 
alternative registration of the Incentive Award, treat the Incentive Award as 
SEC Rule 144 "restricted stock," or take such other measures as the Committee 
deems appropriate.

   (g)  The Committee may permit a Holder to satisfy all or part of his or 
her withholding or income tax obligations by having the Company withhold all 
or a portion of any Common Stock that otherwise would be issued to him or her 
or by surrendering all or a portion of any Common Stock that he or she 
previously acquired.  Such Common Stock shall be valued at its Fair Market 
Value on the date when taxes otherwise would be withheld in cash.  Any 
payment of taxes by assigning Common Stock to the Company may be subject to 
restrictions, including any restrictions required by rules of the Securities 
and Exchange Commission.

   (h)  All Incentive Awards shall become 100% vested in the event of death 
or total and permanent disability.

   17.  AMENDMENT AND TERMINATION.

   (a)  The Board of Directors may, in its discretion, amend, suspend, or 
terminate the Plan at any time.  An amendment of the Plan shall be subject to 
the approval of the Company's stockholders to the extent it affects the 
application of the accelerated vesting provisions herein, Section 15, or to 
the extent required by applicable laws, regulations and or rules.

   (b)  The Committee may, with the consent of a Holder, make such 
modifications in the terms and conditions of the Incentive Award as it deems 
advisable or cancel the Incentive Award (with or without consideration) with 
the consent of the Holder.

   (c)  No amendment, suspension, or termination of the Plan will, without 
the consent of the Holder, alter, terminate, impair, or adversely affect any 
right or obligation under any Incentive Award previously granted under the 
Plan.

   (d)  In the event a Holder of Restricted Stock ceases to be an employee, 
all such Holder's Restricted Stock which remains subject to substantial risk 
of forfeiture at the time his or her employment

                                      B-9
<PAGE>

terminates will be repurchased by the Company at the original price at which 
such Restricted Stock had been purchased unless the Committee determines 
otherwise.

   (e)  In the event a Holder of a Performance Award ceases to be an 
employee, all such Holder's Performance Awards will terminate except in the 
case of retirement, death, or Total and Permanent Disability.  The Committee, 
in its discretion, may authorize full or partial payment of Performance 
Awards in all cases involving retirement, death, or permanent and total 
disability.

   (f)  The Committee may in its sole discretion determine, with respect to 
an Incentive Award, that any Holder who is on unpaid leave of absence for any 
reason will be considered as still in the employ of the Company, provided 
that rights to such Incentive Award during an unpaid leave of absence will be 
limited to the extent to which such right was earned or vested at the 
commencement of such leave of absence.

   18.  EFFECTIVE DATE OF PLAN AND DURATION OF PLAN.

   This Plan will become effective upon approval by the stockholders of the 
Company within twelve (12) months following the date of its adoption by the 
Board of Directors.  Unless previously terminated by the Board of Directors, 
the Plan will terminate ten (10) years after its approval by the stockholders 
of the Company.




                                      B-10
<PAGE>

                            GENSIA SICOR INC.

           PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS 
                FOR THE ANNUAL MEETING - SEPTEMBER 9, 1997

    DAVID F. HALE and WESLEY N. FACH, or each of them, each with the power of
substitution, are hereby authorized to represent as proxies and vote all 
shares of stock of Gensia Sicor Inc. (the "Company") the undersigned is 
entitled to vote at the Annual Meeting of Stockholders of the Company to be 
held at the Hyatt Regency La Jolla, 3777 La Jolla Village Drive, La Jolla, 
California on Tuesday, September 9, 1997 at 11:00 a.m. or at any postponement 
or adjournment thereof, and instructs said proxies to vote as follows:

Shares represented by this proxy will be voted as directed by the 
stockholder. IF NO SUCH DIRECTIONS ARE INDICATED, THE PROXIES WILL HAVE 
AUTHORITY TO VOTE FOR THE ELECTION OF THE THREE NOMINEES FOR CLASS II 
DIRECTORS AND FOR ITEMS 2, 3, 4 AND 5.

               (continued and to be signed on reverse side)

- -------------------------------------------------------------------------------
                           FOLD AND DETACH HERE

<PAGE>

THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE ELECTION OF THE THREE 
NOMINEES FOR CLASS II DIRECTORS AND FOR ITEMS 2, 3, 4 AND 5.

                                                             Please mark 
                                                              your votes
                                                             as indicated 
                                                           in this example  /X/



                                      FOR                     WITHHOLD    
                              all nominees listed             AUTHORITY   
                               below (except as            to vote for all
                            marked to the contrary)     nominees listed below

1. ELECTION OF DIRECTORS.

   Nominees:  Carlos A. Ferrer    Carlo Salvi
              L. John Wilkerson


(INSTRUCTION: To withhold authority 
to vote for any individual nominee, 
write that nominee's name in the 
space provided below.)


- ---------------------------------------------


                                                      FOR   AGAINST   ABSTAIN
2. To approve the amendment and restatement of 
   the ESPP:

                                                      FOR   AGAINST   ABSTAIN
3. To approve the amendment and restatement of 
   the 1997 Stock Plan:

                                                      FOR   AGAINST   ABSTAIN
4. To approve the Chairman's Options:

                                                      FOR   AGAINST   ABSTAIN

5. To ratify the appointment of Ernst & Young LLP
   as the Company's independent auditors:

6. In their discretion, upon such other business as may properly come 
   before the meeting

PLEASE MARK, SIGN, DATE AND MAIL THIS PROXY CARD
PROMPTLY, USING THE ENCLOSED ENVELOPE.


Signature(s)                                       Dated:               , 1997
            ---------------------------------------       --------------
Please sign exactly as your name or name(s) appear on this proxy. When signing
as attorney, executor, administrator, trustee or guardian, please give full 
title as such. If shares are held jointly, each holder should sign.

- -------------------------------------------------------------------------------
                           FOLD AND DETACH HERE


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