PAINEWEBBER INVESTMENT SERIES
24F-2NT, 1995-12-28
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                       U.S. SECURITIES AND EXCHANGE COMMISSION
                                Washington, D.C. 20549

                                     FORM 24F-2
                           Annual Notice of Securities Sold
                                Pursuant to Rule 24f-2


       1.      Name and address of issuer:

               PaineWebber Investment Series
               1285 Avenue of the Americas
               New York, NY  10019

       2.      Name of each series or class of funds for which this notice is
               filed:

               PaineWebber Global Income Fund (Class A, B, C and D shares)

               PaineWebber Global Energy Fund (Class A, B and D shares)

               PaineWebber Global Growth and Income Fund (Class A, B and D
               shares)

               PaineWebber Europe Growth Fund (Class A, B and D shares)

       3.      Investment Company Act File Number:  811-5259

               Securities Act File Number:  33-11025


       4.      Last day of fiscal year for which this notice is filed:

               October 31, 1995

       5.      Check box if this notice is being filed more than 180 days
               after the close of the issuer's fiscal year for purposes of
               reporting securities sold after the close of the fiscal year
               but before termination of the issuer's 24f-2 declaration:
                                                                           /_/

       6.      Date of termination of issuer's declaration rule 24f-2(a)(1),
               if applicable (see Instruction A.6):


       7.      Number and amount of securities of the same class or series
               which had been registered under the Securities Act of 1933
               other than pursuant to rule 24f-2 in a prior fiscal year, but
               which remained unsold at the beginning of the fiscal year:

               59,739,437 shares representing $592,615,214
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       8.      Number and amount of securities registered during the fiscal
               year other than pursuant to rule 24f-2:

               45,886,686 shares representing $452,901,590

       9.      Number and aggregate sale price of securities sold during the
               fiscal year:

               34,807,847 shares representing $366,659,354

       10.     Number and aggregate sale price of securities sold during the
               fiscal year in reliance upon registration pursuant to rule 24f-
               2:

               34,807,847 shares representing $366,659,354

       11.     Number and aggregate sale price of securities issued during the
               fiscal year in connection with dividend reinvestment plans, if
               applicable (see Instruction B.7):

               6,430,007 shares representing $64,080,795

       12.     Calculation of registration fee:

               (i)      Aggregate sale price of securities
                        sold during the fiscal year in
                        reliance on rule 24f-2 (from Item 10):   $ 366,659,354
                                                                 -------------

               (ii)     Aggregate price of shares issued in
                        connection with dividend reinvestment
                        plans (from Item 11, if applicable):     $  64,080,795
                                                                 -------------

               (iii)    Aggregate price of shares redeemed or 
                        repurchased during the fiscal year
                        (if applicable):                         $ 430,740,149
                                                                 -------------

               (iv)     Aggregate price of shares redeemed
                        or repurchased and previously applied

                        as a reduction to filing fees pursuant   $            
                        to rule 24e-2 (if applicable):           -------------

               (v)      Net aggregate price of securities
                        sold and issued during the fiscal
                        year in reliance on rule 24f-2 [line
                        (i), plus line (ii), less line (iii),
                        plus line (iv)] (if applicable):         $           0
                                                                 -------------


                                                                               2
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           (vi)         Multiplier prescribed by Section 6(b)
                        of the Securities Act of 1933 or
                        other applicable law or regulation
                        (see Instruction C.6):                   $           0
                                                                 -------------

       13.     Check box if fees are being remitted to the Commission's
               lockbox depository as described in section 3a of the
               Commission's Rules of Informal and Other Procedures (17 CFR
               202.3a).
                                                                           /_/

               Date of mailing or wire transfer of filing fees to the
               Commission's lockbox depository:




                                     SIGNATURES

       This report has been signed below by the following persons on behalf of
       the issuer and in the capacities and on the dates indicated.

       By (Signature and Title)                  /s/ Paul H. Schubert
                                                 --------------------------
                                                 Paul H. Schubert
                                                 Vice President and Assistant
                                                 Treasurer
                                                 ---------------------------

       Date:  December 27, 1995
              ------------------------





















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                             KIRKPATRICK & LOCKHART LLP
                                 1800 M Street, N.W.
                               Washington, D.C.  20036
                                    (202) 778-9000

     ELINOR W. GAMMON
     (202) 778-9090

                                  December 28, 1995


     PaineWebber Investment Series
     1285 Avenue of the Americas
     New York, New York  10019

     Dear Sir or Madam:

              PaineWebber Investment Series ("Trust") is an unincorporated
     voluntary association organized under the laws of the Commonwealth of
     Massachusetts on December 22, 1986.  During the its fiscal year ended
     October 31, 1995, the Trust had four operating series of shares of
     beneficial interest:  PaineWebber Global Income Fund, PaineWebber Global
     Energy Fund, PaineWebber Global Growth and Income and PaineWebber Europe
     Growth Fund.  We understand that the Trust is about to file a Rule 24f-2
     Notice pursuant to Rule 24f-2 under the Investment Company Act of 1940, as
     amended ("1940 Act"), for the purpose of making definite the number of
     shares of each series which it has registered under the Securities Act of
     1933, as amended ("1933 Act"), and which were sold during the fiscal year
     ended October 31, 1995.

              We have, as counsel, participated in various business and other
     matters relating to the Trust.  We have examined copies, either certified
     or otherwise proved to be genuine, of the Declaration of Trust and By-Laws
     of the Trust, the minutes of meetings of the trustees and other documents
     relating to the organization and operation of the Trust, and we are
     generally familiar with its business affairs.  Based on the foregoing, it
     is our opinion that the shares of the Trust sold during its fiscal year
     ended October 31, 1995, the registration of which will be made definite by
     the filing of the Rule 24f-2 Notice, were legally issued, fully paid and
     non-assessable.  

          The Trust is an entity of the type commonly known as a "Massachusetts
     business trust."  Under Massachusetts law, shareholders could, under
     certain circumstances, be held personally liable for the obligations of
     the Trust.  The Declaration of Trust states that creditors of, contractors
     with, and claimants against the Trust or a particular series shall look
     only to the assets of the Trust or such series for payment.  It also
     requires that notice of such disclaimer be given in each note, bond,
     contact, certificate, undertaking or instrument made or issued by the
     officers or the trustees of the Trust on behalf of the Trust.  The
     Declaration of Trust further provides:  (i) for indemnification from the
     assets of the series for all loss and expense of any shareholder held
     personally liable for the obligations of the Trust or a particular series
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     PaineWebber Investment Series
     December 28, 1995
     Page 2


     by virtue of ownership of shares of such series; and (ii) for such series
     to assume the defense of any claim against the shareholder for any act or
     obligation of such series.  Thus, the risk of a shareholder incurring
     financial loss on account of shareholder liability is limited to
     circumstances in which the Trust or series would be unable to meet its
     obligations.
       
          We hereby consent to this opinion accompanying the Rule 24f-2 Notice
     which you are about to file with the Securities and Exchange Commission.

                                       Very truly yours,

                                       KIRKPATRICK & LOCKHART LLP


                                            /s/ Elinor W. Gammon
                                       By:--------------------------
                                                Elinor W. Gammon
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