PAINEWEBBER INVESTMENT SERIES
497, 1995-04-03
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                           PAINEWEBBER EUROPE GROWTH FUND 
                      PAINEWEBBER GLOBAL GROWTH AND INCOME FUND

                    SUPPLEMENT TO PROSPECTUS DATED MARCH 1, 1995 


     The following amends the information appearing under the caption
     "Management" on page 36 of the Prospectus:

              GE Investment Management Incorporated ("GEIM") now serves as sub-
     adviser for PaineWebber Europe Growth ("Europe Growth Fund") and for the
     equity securities portion of the portfolio of PaineWebber Global Growth
     and Income Fund ("Global Growth and Income Fund") pursuant to an interim
     sub-advisory agreement ("Interim Agreement") between Mitchell Hutchins
     Asset Management Inc. ("Mitchell Hutchins") and GEIM that was approved by
     the board of trustees of PaineWebber Investment Series ("Trust").  Under
     the Interim Agreement, GEIM makes and implements all investment decisions
     with respect to the securities held in Europe Growth Fund's portfolio and
     the equity securities held in Global Growth and Income Fund's portfolio. 
     Under its existing Investment Advisory and Administration Contract with
     respect to the two Funds, Mitchell Hutchins supervises the activities of
     GEIM with respect to each Fund and continues to supervise all other
     aspects of that Fund's operations.  Mitchell Hutchins also continues to
     make all decisions concerning the allocation of the Global Growth and
     Income Fund's portfolio between debt and equity securities and to
     implement all investment decisions with respect to the non-equity
     securities portion of that Fund's portfolio.  With respect to Europe
     Growth Fund, Mitchell Hutchins (not the Fund) pays GEIM for its services
     under the Interim Agreement at the annual rate of 0.31% of Europe Growth
     Fund's average daily net assets up to $500 million, 0.29% of the Fund's
     average daily net assets in excess of $500 million to $1 billion and
     0.265% of the Fund's average daily net assets in excess of $1 billion. 
     Europe Growth Fund had approximately $105.7 million in net assets as of
     February 28, 1995.  With respect to Global Growth and Income Fund,
     Mitchell Hutchins (not the Fund) pays GEIM for its services under the
     Interim Agreement at the annual rate of 0.29% of Global Growth and Income
     Fund's average daily net assets attributable to the equity securities
     portion of that Fund's portfolio.  The Interim Agreement will continue in
     effect with respect to each Fund for the shorter of 120 days from March
     23, 1995 (the date of the Interim Agreement) or the date that a new sub-
     advisory agreement is approved by that Fund's shareholders.

              GEIM is located at 3003 Summer Street, P.O. Box 7900, Stamford
     Connecticut 06904 and is a wholly owned subsidiary of General Electric
     Company.  GEIM is a registered investment adviser, and its principal
     officers and directors serve in similar capacities with respect to General
     Electric Investment Corporation ("GEIC"), also a registered investment
     adviser and a wholly owned subsidiary of General Electric Company.  GEIM
     and GEIC together provide investment management services to various
     institutional accounts with total assets of approximately $45.8 billion as
     of February 28, 1995.
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              The Trust's board of trustees expects to call a special meeting
     of shareholders of each Fund prior to the termination of the Interim
     Agreement.

     The following replaces the fourth and fifth paragraphs appearing under the
     caption "Management" on page 37 of the Prospectus.

              Effective March 23, 1995, Ralph R. Layman became the individual
     primarily responsible for the day-to-day management of Europe Growth
     Fund's portfolio and the equity securities portion of Global Growth and
     Income Fund's portfolio.  Mr. Layman is an executive vice president and a
     senior investment manager of GEIM and GEIC.  From 1989 to 1991, Mr. Layman
     served as executive vice president, partner and portfolio manager of
     Northern Capital Management Co. and, prior thereto, served as vice
     president and portfolio manager of Templeton Investment Counsel.  Stuart
     Waugh, a vice president of the Trust and a managing director of global
     fixed income investments of Mitchell Hutchins, continues to be responsible
     for the day-to-day management of the debt securities portion of Global
     Growth and Income Fund's portfolio.  Mr. Waugh has been employed by
     Mitchell Hutchins as a portfolio manager for the last eight years.

     Dated:  March 23, 1995
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