PAINEWEBBER INVESTMENT SERIES
24F-2NT, 1999-01-26
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                             UNITED STATES                     OMB APPROVAL

                                                         -----------------------
                                                         -----------------------
                   SECURITIES AND EXCHANGE COMMISSION    OMB Number: 3235-0456
                         Washington, D.C. 20549          Expires:August 31, 2000
                                                         Estimated average
                                                         burden
                                                         hours per response.1
                                                         -----------------------
                               FORM 24F-2
                    ANNUAL NOTICE OF SECURITIES SOLD
                         PURSUANT TO RULE 24F-2

                Read        instructions at end of Form before preparing Form.

- --------------------------------------------------------------------------------
    1.   Name and address of issuer:

         PaineWebber Investment Series
         1285 Avenue of the Americas
         New York, NY 10019

- --------------------------------------------------------------------------------
    2.   The name of each series or class of  securities  for which this Form is
         filed  (if the  form is being  filed  for all  series  and  classes  of
         securities  of the  issuer,  check  the box but do not list  series  or
         classes): /X/


- --------------------------------------------------------------------------------
    3.    Investment Company Act File Number:

            811-5259

         Securities Act File Number:

            33-11025


- --------------------------------------------------------------------------------
    4(a). Last day of fiscal year for which this Form is filed:

            October 31, 1998


- --------------------------------------------------------------------------------
    4(b). / /    Check box if this Form is being filed late (i.e., more than
                 90 calendar days after the end of the issuer's fiscal year).
                 (See Instruction A.2)

    NOTE:  IF THE FORM IS BEING FILED LATE, INTEREST MUST BE PAID ON THE
         REGISTRATION FEE DUE.


- --------------------------------------------------------------------------------
    4(c). / /    Check box if this is the last time the issuer will be filing
                 this Form.


<PAGE>


- --------------------------------------------------------------------------------
    5. Calculation of registration fee:

        (i)  Aggregate sale price of                             $   220,513,631
             securities sold during the                           --------------
             fiscal year pursuant to
             section 24(f):
             

        (ii) Aggregate price of
             securities redeemed or          $   390,939,942
             repurchased during the           --------------
             fiscal year


        (iii)Aggregate  price of securities
             redeemed or repurchased during  $   588,278,122
             any prior fiscal year ending     --------------
             no earlier than October 1,     
             1995 that were not               
             previously used to reduce
             registration fees payable
             to the Commission:
             

        (iv) Total available redemption credits [add Items      - $  979,218,064
             5(ii) and 5(iii)]:                                    -------------
                                                                         
         (v) Net sales - if item 5(i) is
             greater than Item 5(iv)                               
             [subtract item 5(iv) from                            $            0
             Item 5(i)]:                                           -------------
             

    ---------------------------------------------------------------
        (vi) Redemption credits
             available for use in future     $(758,704,433)
                                              -------------
             years  -- if Item 5(i) is
             less than Item 5(iv)
             [subtract Item 5(iv) from
             Item 5(i)]:
    ---------------------------------------------------------------

        (vii) Multiplier for determining
             registration fee (See                             x $      0.000278
                                                                  --------------
             Instruction C.9):

        (viii) Registration fee due [multiply Item 5(v) by Item
             5(vii)] (enter "0" if no                              = $         0
             fee is due):                                         --------------

    ---------------------------------------------------------------

     6.   Prepaid Shares

           If the response to Item 5(i) was determined by deducting an amount of
           securities  that were  registered  under the  Securities  Act of 1933
           pursuant to rule 24e-2 as in effect  before  October 11,  1997,  then
           report the  amount of  securities  (number of shares or other  units)
           deducted  here: 0. If there is a number of shares or other units that
           were registered pursuant to rule 24e-2 remaining unsold at the end of
           the fiscal year for which this form is filed that are  available  for
           use by the issuer in future  fiscal  years,  then  state that  number
           here: 150,284,728.

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    7.    Interest due - if this Form is being filed more than 90 days after the
          end of the Issuer's fiscal year (see Instruction D):

                                                                   + $         0
                                                                      ----------

- --------------------------------------------------------------------------------
     8.   Total of the amount of the  registration fee due plus any interest due
          [line 5(viii) plus line 7]:

                                                                   = $         0
                                                                      ==========


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<PAGE>

- --------------------------------------------------------------------------------
     9. Date  the  registration  fee and any  interest  payment  was sent to the
        Commission's lockbox depository:



                Method of Delivery:

                           / / Wire Transfer

                           / / Mail or other means

- --------------------------------------------------------------------------------

                                  SIGNATURES


This  report has been  signed  below by the  following  persons on behalf of the
issuer and in the capacities and on the dates indicated.


By (Signature and Title)*     /s/ John J. Lee
                              ---------------
                              JOHN J. LEE

                              VICE PRESIDENT AND ASSISTANT TREASURER

Date: JANUARY 26, 1999

 *Please print the name and title of the signing officer below the signature.


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<PAGE>


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