ATRIX LABORATORIES INC
8-K, 1998-12-09
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K
                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


                                November 24, 1998
                        ---------------------------------
                        (Date of earliest event reported)


                            ATRIX LABORATORIES, INC.
             ------------------------------------------------------
             (Exact name of Registrant as specified in its charter)


<TABLE>
<CAPTION>
          Delaware                       0-18231                          84-1043826
- ----------------------------      ---------------------        ---------------------------------
<S>                               <C>                          <C>
(State or Other Jurisdiction      (Commission File No.)        (IRS Employer Identification No.)
      of Incorporation)
</TABLE>


                2579 Midpoint Drive, Fort Collins, Colorado 80525
          ------------------------------------------------------------
          (Address of principal executive offices, including zip code)


                                 (970) 482-5868
              ----------------------------------------------------
              (Registrant's telephone number, including area code)




                                       1
<PAGE>   2



ITEM 2.  ACQUISITION OR DISPOSITION OF ASSETS.

        On November 24, 1998 Atrix Laboratories, Inc. a Delaware corporation
(the "Registrant"), completed the acquisition of ViroTex Corporation, a Delaware
corporation ("ViroTex"), through the merger of its wholly-owned subsidiary,
Atrix Acquisition Corporation, a Delaware corporation, with and into ViroTex.
ViroTex develops over-the-counter and prescription products based on proprietary
drug delivery systems that provide topical and transmucosal delivery of
medications requiring quick onset of action.

        Under the terms of the Agreement and Plan of Reorganization dated
November 24, 1998 (the "Merger Agreement"), the stockholders of ViroTex are
entitled to receive $7.5 million in cash and $500,000 in value of shares of the
Registrant's common stock, $.001 par value (the "Common Stock"). In addition,
the ViroTex stockholders are entitled to receive additional consideration of up
to $3,000,000, payable in shares of Common Stock or cash, upon satisfaction of
certain earn-out events set forth in the Merger Agreement related to the
performance of certain products of ViroTex. The Registrant also issued a warrant
to purchase shares of Common Stock in replacement of a warrant to purchase
shares of ViroTex common stock, and agreed to replace certain options held by
employees of Virotex who will become employees or consultants of the Registrant.
Only stockholders of ViroTex who beneficially owned more than 1% of the total
outstanding shares of ViroTex, on a fully diluted basis, as of November 24,
1998, are entitled to receive Common Stock. All other stockholders will receive
cash in lieu of Common Stock. The consideration paid under the Merger Agreement
was determined through arms-length negotiations between the parties and the cash
portion of the purchase price was funded through the Registrant's cash on hand.

         The foregoing summary of the Merger Agreement does not purport to be
complete and is subject to, and qualified in its entirety by reference to, the
provisions of the Merger Agreement which is filed as an Exhibit to this Current
Report on Form 8-K .



                                       2


<PAGE>   3



ITEM 7.  FINANCIAL STATEMENT, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS

         (a)      The financial statements of ViroTex will be filed by an
                  amendment no later than 60 days from the date this Current
                  Report on Form 8-K must be filed.

         (b)      The pro forma financial statements of the Registrant will be
                  filed by an amendment no later than 60 days from the date this
                  Current Report on Form 8-K must be filed.



         (c)      Exhibits.

                  10.1     Agreement and Plan of Reorganization dated November
                           24, 1998 by and among Atrix Laboratories, Inc., Atrix
                           Acquisition Corporation and ViroTex Corporation.

                  10.2     Certificate of Merger of Atrix Acquisition
                           Corporation and ViroTex Corporation dated November
                           24, 1998.

                  99.1     Text of Press Release dated November 30, 1998



                                       3
<PAGE>   4



                                   SIGNATURES


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized, on this 8th day of December, 1998.

                                      ATRIX LABORATORIES, INC.



                                      By: /s/ BRIAN G. RICHMOND
                                          --------------------------------------
                                          Brian G. Richmond
                                          Vice President, Finance
                                          and Assistant Secretary



                                       4


<PAGE>   5



                                  Exhibit Index
                                  -------------


                  10.1     Agreement and Plan of Reorganization dated November
                           24, 1998 by and among Atrix Laboratories, Inc., Atrix
                           Acquisition Corporation and ViroTex Corporation.

                  10.2     Certificate of Merger of Atrix Acquisition
                           Corporation and ViroTex Corporation dated November
                           24, 1998.

                  99.1     Text of Press Release dated November 30, 1998



                                       5

<PAGE>   1
                                                                    EXHIBIT 10.1


                      AGREEMENT AND PLAN OF REORGANIZATION



                                  BY AND AMONG



                            ATRIX LABORATORIES, INC.

                          ATRIX ACQUISITION CORPORATION

                                       AND

                               VIROTEX CORPORATION







                          Dated as of November 24, 1998


<PAGE>   2



                                TABLE OF CONTENTS



<TABLE>
<CAPTION>
                                                                                                           Page No.

<S>                                                                                                       <C>
ARTICLE I DEFINITIONS.............................................................................................2


ARTICLE II THE MERGER.............................................................................................8

   Section 2.01. The Merger.......................................................................................8
   Section 2.02. Effective Time...................................................................................8
   Section 2.03. Effect of the Merger.............................................................................8
   Section 2.04. Effect of Merger on the Capital Stock of the Constituent Corporations............................9
   Section 2.05. Merger Consideration............................................................................11
   Section 2.06. Payment of Merger Consideration.................................................................16
   Section 2.07. Escrow Deposit..................................................................................17
   Section 2.08. Dissenting Shares...............................................................................17
   Section 2.09. No Further Ownership Rights in Company Capital Stock............................................18
   Section 2.10. Lost, Stolen or Destroyed Certificates..........................................................18
   Section 2.11. Fractional Shares...............................................................................18
   Section 2.12. No Liability....................................................................................18
   Section 2.13. Closing Deliveries..............................................................................19
   Section 2.14. Taking of Necessary Action; Further Action......................................................20

ARTICLE III REPRESENTATIONS AND WARRANTIES OF THE COMPANY........................................................20

   Section 3.01. Organization of the Company.....................................................................20
   Section 3.02. Subsidiaries....................................................................................21
   Section 3.03. Company Capital Structure.......................................................................21
   Section 3.04. Authority.......................................................................................22
   Section 3.05. No Conflict.....................................................................................23
   Section 3.06. Consents........................................................................................23
   Section 3.07. Company Financial Statements....................................................................23
   Section 3.08. No Undisclosed Liabilities......................................................................24
   Section 3.09. Products/Product Liability......................................................................24
   Section 3.10. Loans, Notes, Cash, Accounts Receivable and Accounts Payable....................................25
   Section 3.11. Projections.....................................................................................25
   Section 3.12. Absence of Certain Changes......................................................................26
   Section 3.13. Tax Matters.....................................................................................27
   Section 3.14. Restrictions on Business Activities.............................................................30
</TABLE>

<PAGE>   3
<TABLE>
<CAPTION>
                                                                                                           Page No.

<S>                                                                                                       <C>
   Section 3.15. Title of Properties; Absence of Liens and Encumbrances; Condition of Equipment..................30
   Section 3.16. Intellectual Property...........................................................................31
   Section 3.17. Agreements, Contracts and Commitments...........................................................35
   Section 3.18. Interested Party Transactions...................................................................37
   Section 3.19. Governmental Authorization......................................................................37
   Section 3.20. Regulatory Reports..............................................................................37
   Section 3.21. Litigation......................................................................................38
   Section 3.22. Minute Books....................................................................................38
   Section 3.23. Environmental Matters...........................................................................38
   Section 3.24. Brokers' and Finders' Fees and Third Party Expenses.............................................38
   Section 3.25. Employee Benefit Plans and Compensation.........................................................39
   Section 3.26. Insurance.......................................................................................42
   Section 3.27. Compliance with Laws............................................................................43
   Section 3.28. Warranties; Indemnities.........................................................................43
   Section 3.29. Conflicts of Interest...........................................................................43
   Section 3.30. Complete Copies of Materials....................................................................43
   Section 3.31. Representations Complete........................................................................43

ARTICLE IV REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB...............................................44

   Section 4.01. Organization, Standing and Power................................................................44
   Section 4.02. Authority.......................................................................................44
   Section 4.03. Brokers' and Finders Fees.......................................................................44
   Section 4.04. No Conflict.....................................................................................44
   Section 4.05. Consents........................................................................................45
   Section 4.06. Compliance with Laws............................................................................45
   Section 4.07. SEC Reports.....................................................................................45
   Section 4.08. Financial Capability............................................................................46
   Section 4.09. Parent Capital Structure........................................................................46

ARTICLE V ADDITIONAL AGREEMENTS..................................................................................47

   Section 5.01. Expenses........................................................................................47
   Section 5.02. Public Disclosure...............................................................................47
   Section 5.03. S-8 Registration................................................................................47
   Section 5.04. Registration Statement..........................................................................47
   Section 5.05. Registration Procedures.........................................................................48
   Section 5.06. Indemnification.................................................................................50
   Section 5.07. Exculpation for Director Liability..............................................................50
   Section 5.08. Lease Termination...............................................................................50
   Section 5.09. Products Liability Insurance....................................................................51

ARTICLE VI SURVIVAL, INDEMNIFICATION.............................................................................51
</TABLE>



                                       2
<PAGE>   4
<TABLE>
<CAPTION>
                                                                                                           Page No.

<S>                                                                                                       <C>
ARTICLE VII GENERAL PROVISIONS...................................................................................52

   Section 7.01. Notices.........................................................................................52
   Section 7.02. Disclosure Schedule.............................................................................53
   Section 7.03. Interpretation..................................................................................53
   Section 7.04. Counterparts....................................................................................54
   Section 7.05. Entire Agreement; Assignment....................................................................54
   Section 7.06. Third Party Beneficiaries.......................................................................54
   Section 7.07. Severability....................................................................................54
   Section 7.08. Other Remedies..................................................................................54
   Section 7.09. Governing Law...................................................................................55
   Section 7.10. Arbitration.....................................................................................55
   Section 7.11. Amendment.......................................................................................55
   Section 7.12. Extension: Waiver...............................................................................56
   Section 7.13. Rules of Construction...........................................................................56
   Section 7.14. Knowledge.......................................................................................56




Exhibit A                  Form of Personal Services Agreement..................................................A-1
Exhibit B                  Form of Investment Letter............................................................B-1
Exhibit C                  Forms of Transmittal Letters.........................................................C-1
Exhibit D                  Form of Certificate of Merger........................................................D-1
Exhibit E                  Form of Contingent Escrow Agreement..................................................E-1
Exhibit F                  Form of Indemnity and Escrow Agreement...............................................F-1
Exhibit G                  Financial Projections................................................................G-1
Exhibit H                  Form of Cooley Godward LLP Opinion...................................................H-1
Exhibit I                  Key Employees........................................................................I-1
Exhibit J                  Form of Non-Competition Agreement....................................................J-1
Exhibit K                  Person Executing Personal Services Agreement.........................................K-1
Exhibit L                  Form of Company Officer's Certificate................................................L-1
Exhibit M                  [Reserved]...........................................................................M-1
Exhibit N                  Form of Parent Officer's Certificate.................................................N-1
Exhibit O                  Form of Morrison & Foerster LLP Opinion..............................................O-1
Exhibit P                  Form of Assignment and Transfer Agreement............................................P-1
Exhibit Q                  Form of Consent to Conversion of Preferred Stock.....................................Q-1
Exhibit R                  Form of Substitute Option Agreement..................................................R-1
Exhibit S                  Form of Parent Warrant...............................................................S-1
Exhibit T                  Form of Option Exercise..............................................................T-1
</TABLE>



                                       3
<PAGE>   5


                      AGREEMENT AND PLAN OF REORGANIZATION

         This Agreement and Plan of Reorganization (the "Agreement") is made and
entered into as of November 24, 1998 among Atrix Laboratories, Inc., a Delaware
corporation ("Parent"), Atrix Acquisition Corporation, a Delaware corporation
and a wholly-owned subsidiary of Parent ("Merger Sub"), and ViroTex Corporation,
a Delaware corporation (the "Company").

                                    RECITALS

         A. The Boards of Directors of each of the Company, Parent and Merger
Sub believe it is in the best interests of each company and its respective
shareholders that Parent acquire the Company through the statutory merger of
Merger Sub with and into the Company (the "Merger") and, in furtherance thereof,
have approved the Merger.

         B. Pursuant to the Merger, among other things, all of the issued and
outstanding common stock of the Company shall be converted into the right to
receive cash and/or shares of the $.001 par value common stock of Parent
("Parent Common Stock"). All outstanding preferred stock, warrants, Cash-Out
Options (defined below) and other securities or instruments convertible into
capital stock of the Company that are not converted into common stock of the
Company or exercised, as applicable, on or prior to the Closing Date shall be
assumed by Parent as set forth herein.

         C. A portion of the cash consideration otherwise payable by Parent to
the Principal Stockholders (defined below) in connection with the Merger shall
be placed in escrow by Parent for purposes of satisfying damages, losses,
expenses and other similar charges which result from breaches of
representations, warranties and covenants.

         D. The Company and the Principal Stockholders, on the one hand, and
Parent and Merger Sub, on the other hand, desire to make certain
representations, warranties, covenants and other agreements in connection with
the Merger.

         NOW, THEREFORE, in consideration of the foregoing recitals and the
covenants, promises and representations set forth herein, and for other good and
valuable consideration, the parties agree as follows:



<PAGE>   6

                                    ARTICLE I

                                   DEFINITIONS

          (a) The following terms, as used herein, have the following meanings:

               "Acne Product" means the product using the Company's
          solvent/microparticulate drug delivery technology containing dapsone
          for the topical treatment of human skin disease with an initial
          indication for acne.

               "Affiliate" means, with respect to any Person, any other Person
          directly or indirectly controlling, controlled by, or under common
          control with such Person or an officer, director, holder of 10% or
          more of the outstanding equity securities of such Person, or an
          Immediate Family Member of any of the foregoing.

               "Assumed Options" shall mean all unexercised Company Options held
          by Jeffrey M. Soinski, Anthony A. Brown, David W. Osborne, Ph.D.,
          Meidong Yang, Ph.D. and Gilles Tapolsky, Ph.D. immediately prior to
          the Effective Time.

               "Balance Sheet Date" means September 30, 1998.

               "BEMA" means the Company's proprietary bioerodible mucoadhesive
          film.

               "BEMA-Dyclonine Canker Sore Disc" means a product using BEMA
          technology containing dyclonine cut into discs for the treatment of
          canker sores under the OTC monograph for oral care topical analgesics.

               "BEMA-Dyclonine Strips" means a proposed Rx product using BEMA
          technology containing dyclonine cut into strips for local dental
          anesthesia, and requiring submission of a New Drug Application under
          current FDA regulations.

               "BEMA-Nicotine" means a proposed Rx product using BEMA technology
          containing nicotine for smoking cessation, and requiring submission of
          a New Drug Application under current FDA regulations.

               "Benzocaine Canker Sore Product" means a product using the
          Company's proprietary mucocutaneous absorption gel drug delivery
          technology containing benzocaine for the topical treatment of canker
          sores.

               "Cash-Out Options" shall mean all Company Options that are not
          Assumed Options.

               "CERCLA" means the Comprehensive Environmental Response,
          Compensation and Liability Act of 1980, as amended, and any
          regulations promulgated thereunder.



                                       2
<PAGE>   7

               "Closing Date" means the date of the Closing.

               "Code" means the Internal Revenue Code of 1986, as amended.

               "Commercialized" means the date on which the Company, its
          Affiliates or its sublicensee first sells the relevant Company Product
          for use or consumption to an unaffiliated third party in an arms'
          length transaction.

               "Company Capital Stock" shall mean (i) shares of Company Common
          Stock, (ii) shares of Preferred Stock, and (iii) any other capital
          stock of the Company.

               "Company Common Stock" shall mean shares of common stock of the
          Company, $.001 par value per share.

               "Company Options" shall mean all issued and outstanding options,
          warrants (other than the GulfStar Warrant) or other rights to purchase
          Company Capital Stock (whether or not vested) held by consultants,
          employees or directors of the Company or any other person.

               "Confidential Information" means any information relating to the
          properties, prospects, products, services or operations of the Company
          or any direct or indirect Affiliate thereof that is not generally
          known, is proprietary to the Company or such Affiliate and is made
          known to such Person or learned or acquired by such Person while such
          Person was an officer, director, employee or independent contractor of
          the Company, including, without limitation, information relating to
          the software developed by the Company, information as to sources of,
          and arrangements for, hardware supplied to customers or clients of the
          Company, submission and proposal procedures of the Company, customer
          or contact lists, information concerning trade secrets of the Company,
          or any of its Affiliates, any improvements relating to the products of
          the Company in accounting, marketing, selling, leasing, financing and
          other business methods and techniques, and any information obtained by
          the Stockholders' Representatives under Section 2.05(e), whether such
          information relates to the Company or Parent.

               However, Confidential Information shall not include (i) at the
          time of disclosure to any Person such information that was in the
          public domain or later entered the public domain other than as a
          result of a breach of an obligation herein; or (ii) subsequent to
          disclosure to any Person, such Person received such information from a
          third party under no obligation to maintain such information in
          confidence, and the third party came into possession of such
          information other than as a result of a breach of an obligation
          herein.

               "Current Balance Sheet" means the balance sheet of the Company as
          of September 30, 1998.



                                       3
<PAGE>   8

               "Environmental Laws" means any and all federal, state, local and
          foreign statutes, laws, judicial decisions, regulations, ordinances,
          rules, judgments, orders, decrees, codes, plans, injunctions, permits,
          concessions, grants, franchises, licenses, agreements and governmental
          restrictions, now in effect, relating to human health, the environment
          or to emissions, discharges or releases of pollutants, contaminants,
          Hazardous Substances or wastes into the environment, including without
          limitation ambient air, surface water, ground water or land, or
          otherwise relating to the manufacture, processing, distribution, use,
          treatment, storage, disposal, transport or handling of pollutants,
          contaminants, Hazardous Substances or wastes or the clean-up or other
          remediation thereof.

               "Environmental Liabilities" means any and all liabilities of or
          relating to the Company (including any entity which is, in whole or in
          part, a predecessor of the Company), whether vested or unvested,
          contingent or fixed, actual or potential, known or unknown, which (a)
          arise under or relate to matters covered by Environmental Laws and (b)
          relate to actions occurring or conditions existing on or prior to the
          Closing Date.

               "Environmental Permits" means all permits, licenses,
          authorizations, certificates and approvals of governmental authorities
          relating to or required by Environmental Laws and necessary or proper
          for the business of the Company as currently conducted.

               "ERISA" means the Employee Retirement Income Security Act of
          1974, as amended, together with all regulations promulgated
          thereunder.

               "Estimated Third Party Expenses" shall equal the amount of Third
          Party Expenses of the Company estimated in good faith and based on
          reasonable assumptions as of the Closing Date.

               "Exchange Act" means the Securities Exchange Act of 1934, as
          amended, and the rules and regulations promulgated thereunder.

               "External Analgesic Product" means a product using the Company's
          proprietary mucocutaneous absorption gel drug delivery technology
          using the currently monographed OTC external analgesics as set forth
          in 21 CFR section 348 for the topical treatment of arthritis pain,
          bursitis, tendonitis, backaches, muscle stains and sprains and muscle
          cramps.

               "GAAP" means United States generally accepted accounting
          principles, consistently applied on a basis consistent throughout the
          periods indicated and consistent with each other.

               "GulfStar Warrant" means that certain warrant to purchase up to
          52,936 shares of Company Common Stock held by the GulfStar Group.

               "Hazardous Substances" means any toxic, radioactive, corrosive or
          otherwise hazardous substance, including petroleum, its derivatives,
          by-products and other hydrocarbons, or any substance having any
          constituent elements displaying any of the foregoing characteristics,
          including, without limitation, any substance regulated under
          Environmental Laws.



                                       4
<PAGE>   9

               "Immediate Family Member" means, with respect to any Person, such
          Person's spouse, parents, children and siblings.

               "Investment Letter" means the investment letter in the form
          attached hereto as Exhibit B.

               "Lien" means, with respect to any property or asset, any
          mortgage, lien, pledge, charge, security interest, encumbrance or
          other adverse claim of any kind in respect of such property or asset.
          For the purposes of this Agreement, a Person shall be deemed to own
          subject to a Lien any property or asset which it has acquired or holds
          subject to the interest of a vendor or lessor under any conditional
          sale agreement, capital lease or other title retention agreement
          relating to such property or asset.

               "Material Adverse Effect" means, with respect to any Person, any
          material adverse change in, or material adverse effect on, the
          business, assets, results of operations, value or financial or other
          condition of the Person, or any event or circumstance that would
          likely prevent, hinder or materially delay the consummation of any of
          the transactions contemplated by this Agreement and the Related
          Agreements.

               "Minority Stockholder(s)" means those Stockholders of the Company
          that individually own 1% or less of the Total Outstanding Shares.

               "Parent Common Stock" shall mean unregistered shares of the
          common stock, $.001 par value, of Parent.

               "Parent Option" shall mean any option to purchase shares of
          Parent Common Stock issued pursuant to Section 2.04(c) in connection
          with the substitution of an Assumed Option, without any material
          changes to the Assumed Option within the meaning of Section 422 of the
          Code.

               "Parent Warrant" shall mean a warrant to purchase shares of
          Parent Common Stock issued pursuant to Section 2.04(f) in connection
          with the substitution of the GulfStar Warrant in substantially the
          form attached hereto as Exhibit S.

               "Person" means an individual, corporation, partnership,
          association, trust or other entity or organization, including a
          government or political subdivision or an agency or instrumentality
          thereof.

               "Personal Services Agreement" means the employment agreement in
          the form attached hereto as Exhibit A.



                                       5
<PAGE>   10

               "Preferred Stock" shall mean shares of Series A, Series B, Series
          C, Series D, Series E and Series F Convertible Preferred Stock of the
          Company, each with a par value of $.001 per share.

               "Principal Stockholder(s)" means those Stockholders of the
          Company that individually own more than 1% of the Total Outstanding
          Shares.

               "Pro Rata Portion" shall mean with respect to each Stockholder an
          amount determined at the Effective Time equal to the quotient obtained
          by dividing (x) the number of shares of Company Common Stock owned by
          such Stockholder immediately prior to the Effective Time, by (y) the
          Total Outstanding Shares immediately prior to the Effective Time.

               "Related Agreements" shall mean all ancillary agreements required
          in this Agreement to be executed and delivered in connection with the
          transactions contemplated hereby, including the Escrow Agreement, the
          Non-Competition Agreements and the Employment Agreements.

               "SEC" means the United States Securities and Exchange Commission.

               "Securities Act" means the Securities Act of 1933, as amended,
          and the rules and regulations promulgated thereunder.

               "Stockholder(s)" means the record owner of shares of Company
          Capital Stock.

               "Stockholders' Representatives" shall mean William T. Mullaney
          and Anthony A. Brown appointed pursuant to the terms and provisions
          contained in the Transmittal Letter.

               "Subsidiary" means any entity of which securities or other
          ownership interests having ordinary voting power to elect a majority
          of the board of directors or other persons performing similar
          functions are at the time directly or indirectly owned by the Company.

               "Topical Antibiotic Product" means a product using the Company's
          proprietary topical antibiotic gel technology for currently
          monographed OTC topical antibiotic drug ingredients as set forth in 21
          CFR section 333.110 and section 333.120 for the topical treatment of
          minor cuts, scrapes and burns.

               "Total Outstanding Shares" shall be the aggregate number of
          shares of Company Common Stock (including any Company Capital Stock
          and Company Options) outstanding immediately prior to the Effective
          Time.

               "Transmittal Letter" means the transmittal letter in the form
          attached hereto as Exhibit C.



                                       6
<PAGE>   11

               "Wart Removal Product" means a product using the Company's
          proprietary topical wart removal technology for currently monographed
          OTC topical wart removal ingredients.

               "Wound Wash Product" means a product using the Company's
          proprietary topical antiseptic technology for currently monographed
          OTC topical antiseptic drug ingredients as set forth in 21 CFR section
          333.10 and section 333.20 for the topical treatment of minor cuts,
          scrapes and burns.

         (b) Each of the following terms is defined in the Section set forth
opposite such term below:

<TABLE>
<S>                                                                                          <C>    
         Aggregate Initial Payment..................................................................Section 2.05(a)
         Cash Payment Amount........................................................................Section 2.05(a)
         Certificate of Merger.........................................................................Section 2.02
         Closing.......................................................................................Section 2.02
         Closing Date..................................................................................Section 2.02
         Closing Exchange Ratio..................................................................Section 2.05(c)(i)
         Company Intellectual Property..........................................................Section 3.16(a)(ii)
         Company Payment Amount........................................................................Section 5.01
         Company Stock Certificates....................................................................Section 2.05
         Conflict......................................................................................Section 3.05
         Consent of Conversion of Preferred Stock...................................................Section 3.03(b)
         Contingent Escrow Agent................................................................Section 2.06(b)(ii)
         Contingent Escrow Agreement............................................................Section 2.06(b)(ii)
         Contingent Exchange Ratio.............................................................Section 2.05(c)(iii)
         Contract...................................................................................Section 3.17(b)
         Customer Information.......................................................................Section 3.15(d)
         Delaware Law..................................................................................Section 2.01
         Development Obligations....................................................................Section 2.05(e)
         Dissenting Shares.............................................................................Section 2.08
         Earn-Out Event.............................................................................Section 2.05(b)
         Effective Time................................................................................Section 2.02
         Escrow........................................................................................Section 2.07
         Escrow Agent..................................................................................Section 2.07
         Escrow Amount.................................................................................Section 2.07
         Escrow Shares..........................................................................Section 2.06(b)(ii)
         Exchange Agent................................................................................Section 2.05
         Exchange Ratio.........................................................................Section 2.05(c)(ii)
         Governmental Entity...........................................................................Section 3.06
         Indemnity and Escrow Agreement................................................................Section 2.07
         Intellectual Property...................................................................Section 3.16(a)(i)
         Interim Financials............................................................................Section 3.07
         Merger Consideration..........................................................................Section 2.05
         Option Exchange Ratio......................................................................Section 2.04(b)
</TABLE>



                                       7

<PAGE>   12
<TABLE>
<S>                                                                                          <C>    
         Option Exercise Notice.....................................................................Section 3.03(b)
         Option Price...............................................................................Section 2.04(e)
         Permitted Assignee....................................................................Section 2.06(b)(iii)
         Plan.......................................................................................Section 3.03(b)
         Registered Intellectual Property......................................................Section 3.16(a)(iii)
         Registered Shares..........................................................................Section 5.04(a)
         Registration Statement.....................................................................Section 5.04(a)
         Returns................................................................................Section 3.13(a)(ii)
         Surviving Corporation.........................................................................Section 2.01
         Taxes...................................................................................Section 3.13(a)(i)
         Third Party Expenses..........................................................................Section 5.01
         Year-End Financials...........................................................................Section 3.07
</TABLE>

                                   ARTICLE II

                                   THE MERGER

Section 2.01.     THE MERGER.

         At the Effective Time and subject to and upon the terms and conditions
of this Agreement and the applicable provisions of the Delaware Business
Corporation Act ("Delaware Law"), Merger Sub shall be merged with and into the
Company, the separate corporate existence of Merger Sub shall cease and the
Company shall continue as the surviving corporation and as a wholly-owned
subsidiary of Parent. The surviving corporation after the Merger is hereinafter
sometimes referred to as the "Surviving Corporation."

Section 2.02.     EFFECTIVE TIME.

         The closing of the Merger (the "Closing") will take place concurrently
with the execution of this Agreement at the offices of Morrison & Foerster, LLP,
5200 Republic Place, 370 17th Street, Denver, Colorado, unless another place or
time is agreed to in writing by Parent and the Company. The date upon which the
Closing actually occurs is herein referred to as the "Closing Date" and shall be
no later than December 1, 1998. In addition to the deliveries required by the
parties hereto under Section 2.13 of this Agreement, on the Closing Date, the
parties hereto shall cause the Merger to be consummated by filing a Certificate
of Merger (or like instrument) in the form attached hereto as Exhibit D with the
Secretary of State of the State of Delaware (the "Certificate of Merger"), in
accordance with the applicable provisions of Delaware Law (the time of
acceptance by the Secretary of State of the State of Delaware of such filing
being referred to herein as the "Effective Time").

Section 2.03.     EFFECT OF THE MERGER.

               (a) General. At the Effective Time, the effect of the Merger
          shall be as provided in the applicable provisions of Delaware Law. The
          Surviving Corporation may, at any time after the Effective Time, take
          any action (including executing and delivering any document) in the
          name and on behalf of either the Company or Merger Sub in order to
          carry out and effectuate the transactions contemplated by this
          Agreement.



                                       8
<PAGE>   13

               (b) Certificate of Incorporation. The Certificate of
          Incorporation of the Surviving Corporation shall be amended and
          restated at and as of the Effective Time to read as did the
          Certificate of Incorporation of Merger Sub immediately prior to the
          Effective Time (except that the name of the Surviving Corporation
          shall remain unchanged).

               (c) Bylaws. The Bylaws of the Surviving Corporation shall be
          amended and restated at and as of the Effective Time to read as did
          the Bylaws of Merger Sub immediately prior to the Effective Time
          (except that the name of the Surviving Corporation shall remain
          unchanged).

               (d) Officers and Directors. The directors and officers of Merger
          Sub shall become the directors and officers of the Surviving
          Corporation at and as of the Effective Time (retaining their
          respective positions and terms of office).

Section 2.04.     EFFECT OF MERGER ON THE CAPITAL STOCK OF THE CONSTITUENT 
                  CORPORATIONS.

               (a) Effect on Capital Stock. At the Effective Time, by virtue of
          the Merger and without any action on the part of the parties hereto,
          each share of the Company Common Stock issued and outstanding
          immediately prior to the Effective Time (other than any Dissenting
          Shares) will be canceled and extinguished and be converted
          automatically into the right to receive, without interest, such Merger
          Consideration as is payable under Section 2.05, upon the terms and
          subject to conditions set forth below and throughout this Agreement.

               (b) Assumption of Assumed Options. Upon the Closing, each Assumed
          Option will be, in connection with the Merger, replaced by Parent with
          a Parent Option. Each Parent Option shall continue to have, and be
          subject to, the same terms and conditions as the Assumed Option which
          it replaces, except that (i) vesting shall accelerate immediately
          prior to the Closing so that the Assumed Options and the Parent
          Options which replace them are one hundred percent (100%) vested, (ii)
          the per share exercise price under each Parent Option shall be equal
          to the number obtained by dividing (A) the exercise price for a share
          of Company Common Stock subject to the Assumed Option, by (B) the
          Company Common Stock Value (as defined below), (C) multiplied by the
          Parent Common Stock Value (as defined below) (rounded up to the
          nearest whole cent), and (iii) the Parent Option will be exercisable
          for that number of whole shares of Parent Common Stock equal to the
          number obtained by multiplying (A) the number of shares of Company
          Common Stock subject to the Assumed Option, by (B) the Company Common
          Stock Value, divided by (C) the Parent Common Stock Value (rounded
          down to the nearest whole share). The "Company Common Stock Value"
          shall be determined by dividing (A)(1) the Aggregate Initial Payment,
          less (2) Estimated Third Party Expenses in excess of the Company
          Payment Amount, plus (3) $1,342,975 by (B) the Total Outstanding
          Shares. The "Parent Common Stock Value" shall be equal to the average
          closing sale price of a share of Parent Common Stock as reported on



                                       9

<PAGE>   14

          the Nasdaq National Market for the twenty (20) consecutive trading
          days ending three (3) business days prior to the Closing Date.
          Notwithstanding the foregoing, the parties intend that to the extent
          that the Assumed Options are incentive stock options, as that term is
          defined under Section 422 of the Code, at the time of Closing, that
          the Parent Options replacing such Assumed Options also will be
          incentive stock options to the same extent.

               (c) Assumption Agreement. Promptly following the Closing, Parent
          will issue to each holder of an Assumed Option a substitute option
          agreement in the form of Exhibit R and each former holder of an
          Assumed Option shall acknowledge the receipt of same in exchange for
          such holder's Assumed Option.

               (d) Option Status. It is the intention of the parties that Parent
          Options issued by Parent following the Closing will, to the extent
          permitted by applicable law, continue to qualify as incentive stock
          options as defined in Section 422 of the Code to the extent the
          Assumed Options qualified as incentive stock options immediately prior
          to the Closing.

               (e) Termination of Cash-Out Options. Parent shall assume and
          amend the Cash-Out Options as follows: each Cash-Out Option will
          continue to have, and be subject to, the same terms and conditions
          including vesting, as provided in the respective option agreements
          immediately prior to the Effective Time, except that (A) the Cash-Out
          Options will expire on December 8, 1998, unless exercised and (B), at
          the option of the holder, the Cash-Out Options will be exercisable for
          (1) cash in an amount equal to $1.12 per share of Company Common Stock
          underlying the Cash-Out Option immediately prior to the Effective Time
          less, the exercise price per share as set forth in the respective
          option agreement immediately prior to the Effective Time, or (2) each
          option will be exercisable for that number of whole shares of Parent
          Common Stock equal to the product obtained by multiplying the Cash-Out
          Option Exchange Ratio by the number of shares of Company Common Stock
          subject to such Cash-Out Option (rounded to the nearest whole number
          of shares of Parent Common Stock), and the per share exercise price
          shall be equal to the quotient obtained by dividing the exercise price
          for the Cash-Out Option by the Cash-Out Option Exchange Ratio (rounded
          to the nearest whole cent). The Cash-Out Option Exchange Ratio shall
          mean a number equal to the quotient obtained by dividing (x) the
          Aggregate Initial Payment by (y) the average closing sale price of
          Atrix Common Stock as reported on the Nasdaq National Market for
          twenty (20) consecutive trading days ending three (3) business days
          prior to the Closing Date, and dividing such quotient by (z) the Total
          Outstanding Shares. In addition, each holder of a Cash-Out Option who
          exercises the option shall be entitled to participate in such holder's
          pro rata share of the Earn-Out Event payments, if any, under Section
          2.05(b) hereof, as if such holder were a Minority Stockholder or
          Principal Stockholder, as appropriate, as of the Effective Time, and
          shall be treated as a part of the definitions of Principal Stockholder
          and Minority Stockholder for purposes of Section 2.06(b) and 2.06(c),
          respectively.

               (f) Assumption of GulfStar Warrant. Upon the Closing, the
          GulfStar Warrant will be, in connection with the Merger, replaced by
          Parent with a Parent Warrant in the form of Exhibit S.



                                       10

<PAGE>   15

               (g) Capital Stock of Merger Sub. Each share of common stock of
          Merger Sub, $.001 par value per share, issued and outstanding
          immediately prior to the Effective Time shall be converted into and
          exchanged for one validly issued, fully paid and nonassessable share
          of common stock of the Surviving Corporation. Each stock certificate
          of Merger Sub evidencing ownership of any such shares shall continue
          to evidence ownership of such shares of capital stock of the Surviving
          Corporation.

Section 2.05.     MERGER CONSIDERATION.

         As set forth in the Contingent Escrow Agreement, immediately after the
Effective Time, Parent shall deposit with Bank One, Colorado, N.A. (the
"Exchange Agent") (i) the Cash Payment less the Escrow Amount, (ii) certificates
representing $500,000 in value of Parent Common Stock to be issued to the
Principal Stockholders, less cash payments for fractional shares, and (iii) cash
sufficient to make payments in lieu of fractional shares in accordance with
Section 2.11. All of the cash and shares of Parent Common Stock so deposited
with the Exchange Agent, together with any dividends or distributions received
by the Exchange Agent with respect to the shares so deposited, are referred to
collectively as the Exchange Fund. As soon as practicable after the Effective
Time, the Exchange Agent will mail to the registered holders of Company Stock
Certificates (i) a Transmittal Letter, (ii) and instructions for use in
effecting the surrender of Company Stock Certificates in exchange for any cash
payments and, if applicable, certificates representing shares of Parent Common
Stock all in accordance with this Section 2.05. Upon surrender of a Company
Stock Certificate to the Exchange Agent, together with a duly executed Letter of
Transmittal, and such other documents as may reasonably be required by the
Exchange Agent or Parent, (A) the holder of such Company Stock Certificate shall
be entitled to receive in exchange therefor cash and, if applicable, a
certificate representing the number of shares of Parent Common Stock, that such
holder has the right to receive pursuant to this Section 2.05, and (B) the
Company Stock Certificate so surrendered shall be marked "canceled." Until so
surrendered, each outstanding Company Stock Certificate will be deemed for all
corporate purposes, to evidence only the right to receive payment pursuant to
this Article II. In exchange for the Company Stock Certificates, the
Stockholders, excluding holders of Dissenting Shares, shall be entitled to
receive the following consideration (collectively, the "Merger Consideration"):

               (a) Initial Payment. $8,000,000, of which $7,500,000, less
          Estimated Third Party Expenses in excess of the Company Payment
          Amount, shall be payable in cash (the "Cash Payment Amount") and
          $500,000 shall be payable in Parent Common Stock (collectively, the
          "Aggregate Initial Payment").

               (b) Contingent Consideration. In addition, the Stockholders
          (which shall include for purposes of this subsection 2.05(b), holders
          of Assumed Options, excluding holders of Dissenting Shares, shall be
          entitled to receive the following consideration upon satisfaction of
          the conditions set forth below (each a "Earn-Out Event"):

                    (i) $1,000,000 payable in shares of Parent Common Stock or
               cash, in the case of the Minority Stockholders, if the Company


                                       11
<PAGE>   16

               has entered into a valid and binding definitive agreement to
               license or sell its Acne Product prior to December 31, 1999,
               which agreement shall contain customary provisions relating to
               milestone payments, payment of research and development expenses,
               and licensing and royalty fees. Thereafter, this amount shall
               decrease $41,650 on the first day of each month after December
               31, 1999 that the Company has not entered into a valid and
               binding definitive agreement to license or sell its Acne Product;
               provided, however, that no payment shall be due if such agreement
               is not entered into by December 31, 2000.

                    (ii) $250,000 payable in shares of Parent Common Stock or
               cash, in the case of the Minority Stockholders, if the Company
               has Commercialized its External Analgesic Product prior to
               December 31, 1999. Thereafter, this amount shall decrease $10,000
               on the first day of each month after December 31, 1999 that the
               Company has not Commercialized its External Analgesic Product;
               provided, however, that no payment shall be due if the External
               Analgesic Product is not Commercialized by December 31, 2000.

                    (iii) $250,000 payable in shares of Parent Common Stock or
               cash, in the case of the Minority Stockholders, if the Company
               has Commercialized its Benzocaine Canker Sore Product prior to
               December 31, 1999. Thereafter, this amount shall decrease by
               $10,000 on the first day of each month after December 31, 1999
               that the Company has not Commercialized its Benzocaine Canker
               Sore Product; provided, however, that no payment shall be due if
               the Benzocaine Canker Sore Product is not Commercialized by
               December 31, 2000.

                    (iv) $250,000 payable in shares of Parent Common Stock or
               cash, in the case of the Minority Stockholders, if, and only if,
               the Company has Commercialized its Topical Antibiotic Product
               prior to December 31, 2000.

                    (v) $250,000 payable in shares of Parent Common Stock or
               cash, in the case of the Minority Stockholders, if, and only if,
               the Company has Commercialized its Wound Wash Product prior to
               December 31, 2000.

                    (vi) the following consideration payable in shares of Parent
               Common Stock or cash, in the case of the Minority Stockholders:

                         (A) $600,000 if the Company receives or has recognized,
                    in accordance with GAAP, an aggregate of $1,500,000 in any
                    payments (other than payments for reimbursed research and
                    development expenses or royalty fees) with respect to any
                    products relating to or based upon Company Intellectual
                    Property (collectively, "Product Revenue") after the Closing
                    Date and on or prior to December 31, 1999 ; and

                         (B) an additional $200,000 if the Company receives or
                    has recognized in accordance with GAAP an aggregate of
                    $2,000,000 in Product Revenue after the Closing Date and on
                    or prior to December 31, 1999; and


                                       12

<PAGE>   17

                                    (C) an additional $200,000 if the Company
                           receives or has recognized in accordance with GAAP an
                           aggregate of $2,500,000 in Product Revenue after the
                           Closing Date and on or prior to December 31, 1999.

                    In addition, as of December 31, 1999, or as soon as
               practicable thereafter, Parent shall determine all Product
               Revenue received or recognized by the Company, in accordance with
               GAAP, on any products relating to or based upon Company
               Intellectual Property as of such date and Parent shall pay to the
               Stockholders additional consideration payable in Parent Common
               Stock equal to the Product Revenue in excess of $1,500,000 or
               $2,000,000, as the case may be, multiplied by 40%.
               Notwithstanding the above, if the Company subsequently does not
               receive any previously recognized Product Revenue then the future
               payments related to Product Revenue to be made to the
               Stockholders, if any, will be reduced by an amount equal to the
               amount paid to the Stockholders for such Product Revenue not
               actually received by the Company and, provided, further, that if
               no future payments are payable to the Stockholders under this
               Section 2.05(b), the Stockholders shall promptly reimburse Parent
               upon notice for their pro rata portion of such excess payments
               previously paid to the Stockholders.

               (c) Parent Common Stock Payable to Each Principal Stockholder.
          The number of shares of Parent Common Stock each Principal Stockholder
          shall be entitled to receive shall be determined as follows:

                    (i) For the Parent Common Stock issuable under subsection
               2.05(a), each Principal Stockholder shall receive shares of
               Parent Common Stock equal to the product of (x) the Closing
               Exchange Ratio times (y) the number of shares of Company Common
               Stock held of record by such Principal Stockholder immediately
               prior to the Effective Time. For purposes of this subsection
               (c)(i), the "Closing Exchange Ratio" shall mean a number equal to
               the quotient obtained by dividing (x) $500,000, by (y) the
               average closing sale price of Parent Common Stock as reported on
               the Nasdaq National Market for the twenty (20) consecutive
               trading days ending three (3) business days prior to the Closing
               Date, and dividing such quotient by (z) the Total Outstanding
               Shares (Schedule 2.05(c)(i) sets forth (A) the Closing Exchange
               Ratio and the Exchange Ratio, (B) the average closing sale price
               of Parent Common Stock as reported on the Nasdaq National Market
               for the twenty (20) consecutive trading days ending three (3)
               business days prior to the Closing Date, and (C) the Total
               Outstanding Shares);

                    (ii) For the Parent Common Stock issuable upon satisfaction
               of the conditions set forth in subsections 2.05(b)(iv) and
               2.05(b)(v), each Principal Stockholder shall receive shares of
               Parent Common Stock equal to the product of (x) the



                                       13
<PAGE>   18

               Exchange Ratio times (y) the number of shares of Company Common
               Stock held of record by such Principal Stockholder plus the
               number of shares of Company Common Stock underlying an Assumed
               Option held by such Principal Stockholder, immediately prior to
               the Effective Time. For purposes of this subsection (c)(ii), the
               "Exchange Ratio" shall mean, with respect to each Earn-Out Event
               referenced in this subsection (c)(ii), a number equal to the
               quotient obtained by dividing (x) the dollar amount payable in
               Parent Common Stock under such Earn-Out Event, by (y) the average
               closing sale price of Parent Common Stock as reported on the
               Nasdaq National Market for the twenty (20) consecutive trading
               days ending three (3) business days prior to the Closing Date,
               and dividing such quotient by (z) the Total Outstanding Shares;
               and (iii) For the shares of Parent Common Stock issuable pursuant
               to subsections 2.05(b)(i), 2.05(b)(ii), 2.05(b)

                    (iii) and 2.05(b)(vi), each Principal Stockholder shall
               receive shares of Parent Common Stock equal to the product of (x)
               the Contingent Exchange Ratio times (y) the number of shares of
               Company Common Stock held of record by such Principal Stockholder
               plus the number of shares of Company Common Stock underlying an
               Assumed Option held by such Principal Stockholder, immediately
               prior to the Effective Time. For purposes of this subsection
               (c)(iii), the "Contingent Exchange Ratio" shall mean, with
               respect to each Earn-Out Event referenced in this subsection
               (c)(iii), a number equal to the quotient obtained by dividing (x)
               the dollar amount payable in Parent Common Stock under such
               Earn-Out Event by (y) the average closing sale price of Parent
               Common Stock as reported on the Nasdaq National Market for the
               twenty (20) consecutive trading days ending on the last trading
               day of the month in which the conditions to such Earn-Out Event
               is satisfied, and dividing such quotient by (z) the Total
               Outstanding Shares.

               (d) Cash Payable to Stockholder(s).

                    (i) Minority Stockholders.

                         (A) In lieu of receiving shares of Parent Common Stock
                    under subsections 2.05(a) and 2.05(b)(i), 2.05(b)(ii),
                    2.05(b)(iii) and 2.05(b)(vi), each Minority Stockholder
                    shall receive cash in an amount equal to its Pro Rata
                    Portion of the portion of the Merger Consideration to be
                    paid pursuant to each such section less the aggregate option
                    exercise price, if applicable; provided, however, that a
                    Minority Stockholder's Pro Rata Portion shall include shares
                    of Company Common Stock underlying Assumed Options held by
                    such Minority Stockholder, with respect to Earn-Out Event
                    payments, but not otherwise.

                         (B) In lieu of receiving shares of Parent Common Stock
                    under subsections 2.05(b)(iv) and 2.05(b)(v), each Minority
                    Stockholder shall receive cash in an amount equal to (x) its
                    Pro Rata Portion of the portion of the Merger Consideration



                                       14
<PAGE>   19

                    to be paid pursuant to each such section, divided by (y) the
                    average closing sale price of Parent Common Stock as
                    reported on the Nasdaq National Market for the twenty (20)
                    consecutive trading days ending three (3) business days
                    prior to the Closing Date, multiplied by (z) the average
                    closing sale price of Parent Common Stock as reported on the
                    Nasdaq National Market for the twenty (20) consecutive
                    trading days ending on the last trading day of the month in
                    which the conditions to such Earn-Out Event is satisfied;
                    provided, however, that a Minority Stockholder's Pro Rata
                    Portion shall include shares of Company Common Stock
                    underlying Assumed Options held by such Minority
                    Stockholder, with respect to Earn-Out Event payments, but
                    not otherwise.

                         (ii) Principal Stockholders. Each Principal Stockholder
                    shall receive cash in an amount equal to the product of such
                    Principal Stockholder's Pro Rata Portion multiplied by the
                    sum of (x) the Cash Payment Amount less (y) the aggregate
                    exercise price of each Cash-Out Option held by Principal
                    Stockholder, if applicable. Notwithstanding the foregoing,
                    the Cash Payment Amount otherwise payable to the Principal
                    Stockholders shall be reduced by the Escrow Amount in the
                    manner set forth in Section 2.07 herein.

                    (e) Development Obligations. Parent shall use and shall
               cause the Company to use commercially reasonable and diligent
               efforts to (i) license or sell the Acne Product by December 31,
               1999, (ii) develop and commercialize (either directly or
               indirectly) each of the External Analgesic Product and the
               Benzocaine Canker Sore Product prior to December 31, 1999 and
               (iii) develop and commercialize each of the Topical Antibiotic
               Product and the Wound Wash Product by December 31, 2000. Any
               license, sale or development or commercialization agreements
               entered into by Parent or the Company with respect to the
               foregoing shall be done on commercially reasonable terms. As used
               herein, the term "commercially reasonable and diligent efforts"
               will mean, unless the Stockholders' Representatives and the
               Company otherwise agree in writing following the Closing, those
               efforts consistent with the exercise of prudent scientific and
               business judgment, as applied to other products of similar
               potential and market size. Without limiting the generality of the
               foregoing, "commercially reasonable and diligent efforts" shall
               include the dedication of adequate business development resources
               to licensing or selling the Acne Product and adequate
               development, regulatory, sales and marketing and other resources
               for commercializing new products. If Parent decides to abandon
               efforts to license or sell the Acne Product for any reason other
               than unanticipated changes in regulatory affairs, product failure
               or changes in market conditions that make licensing or sale
               infeasible or impractical or if Parent directly or through an
               Affiliate elects to pursue commercialization of the Acne Product,
               then the Earn-Out Event in subsection 2.05(b)(i) shall be deemed
               to have occurred and, for purposes of Section 2.05(b)(vi), the
               Company shall be deemed to have received $1,000,000 for purposes
               of calculating Product Revenue. The Stockholders'


                                       15
<PAGE>   20

               Representatives, or their representatives including an
               independent accounting firm, shall be entitled to request,
               inspect and copy no more than once in any three month period
               (provided, however, that such three month limitation shall not
               apply if the Stockholders' Representatives have reasonable cause
               to believe that Parent or the Company have failed to comply with
               terms and provisions applicable to an Earn-Out Event) and subject
               to reasonable notice and at reasonable times, Parent's or the
               Company's records relating to their efforts to cause the Earn-Out
               Events to occur and the amounts due to the Stockholders under
               Section 2.05(b). All such inspections shall be conducted at the
               Stockholders' expense and are subject to compliance by the
               Stockholders' Representatives, and their representatives, with
               the confidentiality provisions set forth in the Investment
               Letter. In the event that it was determined that the amounts owed
               to the Stockholders under Section 2.05(b) is greater than 5% of
               the amounts actually paid to the Stockholders under Section
               2.05(b), Parent shall pay the reasonable fees, costs and expenses
               of such inspections. Any dispute with respect to the amount of
               the payments to be made to the Stockholders under Section 2.05(b)
               will be submitted to arbitration in accordance with Section 7.10.

Section 2.06.     PAYMENT OF MERGER CONSIDERATION.

          The Merger Consideration shall be due and payable as follows:

               (a) Initial Payment. The Aggregate Initial Payment shall be due
          and payable on the Closing Date in the manner set forth in Section
          2.05. The Cash Payment Amount shall be paid by certified or official
          bank check in immediately available funds to the order of the
          applicable Stockholder or at the option of the Stockholder by wire
          transfer of immediately available funds to an account or accounts to
          be designated by such Stockholder to the Exchange Agent.

               (b) Principal Stockholders' Contingent Consideration.

                    (i) Upon the satisfaction of an Earn-Out Event contained in
               subsections 2.05(b)(i), (ii), (iii) or (vi), the Company shall
               issue or cause to be issued to each Principal Stockholder a
               certificate for the number of shares of Parent Common Stock to
               which such Principal Stockholder is entitled under this Agreement
               within five business days after the last day of the month in
               which the condition for such Earn-Out Event is satisfied.

                    (ii) On the Closing Date, Parent shall deliver the Parent
               Common Stock payable upon satisfaction of the Earn-Out Events
               contained in subsections 2.05(b)(iv) or 2.05(b)(v) (the "Escrow
               Shares") (using the same price per share used to calculate the
               Exchange Ratio in subsection 2.05(c)(ii)) to an escrow agent
               ("Contingent Escrow Agent") to be held in escrow in accordance
               with the terms hereof and the terms of the escrow agreements
               attached hereto as Exhibit E (the "Contingent Escrow Agreement").
               Upon the satisfaction of an Earn-Out Event contained in
               subsections 2.05(b)(iv) or (v), the Company shall cause the
               Contingent Escrow Agent to issue to each Principal Stockholder a
               certificate for the number of shares of Parent Common Stock to
               which such Principal Stockholder is entitled under this
               Agreement, within five business days after the last day of the
               month in which the condition for such Earn-Out Event is
               satisfied.


                                       16
<PAGE>   21
                    (iii) A Principal Stockholder may assign its right to
               receive shares of Parent Common Stock under this subsection
               2.06(b) to another Person or Persons provided the Principal
               Stockholder and such Person or Persons (a "Permitted Assignee")
               have executed an assignment and transfer agreement in the form
               attached hereto as Exhibit P (the "Assignment and Transfer
               Agreement"). 

               (c) Minority Stockholders' Contingent Consideration. Upon the
          satisfaction of an Earn-Out Event contained in subsection 2.05(b) the
          Company shall pay to each Minority Stockholder the cash consideration
          to which each such Minority Stockholder is entitled under this
          Agreement by certified or official bank check in immediately available
          funds to the order of the applicable Minority Stockholder or at the
          option of the Minority Stockholder by wire transfer of immediately
          available funds to an account or accounts designated by such Minority
          Stockholder to Parent at the Closing, payable at the time the shares
          of Parent Common Stock are payable to the Principle Stockholders under
          such Earn-Out Event.

Section 2.07.     ESCROW DEPOSIT.

         Notwithstanding anything to the contrary contained in this Agreement,
Parent shall withhold an aggregate of ten percent (10%) of the Aggregate Initial
Payment from the Cash Payment Amount otherwise payable to the Principal
Stockholders (the "Escrow Amount") pursuant to Article II hereof, and deposit
the Escrow Amount into an interest bearing account (the "Escrow"), to be
governed by the terms hereof and the terms of the indemnity and escrow agreement
attached hereto as Exhibit F (the "Indemnity and Escrow Agreement") and the
escrow agent designated therein (the "Escrow Agent"). The indemnification
obligations of Parent and the Principal Stockholders for a breach of the
representations, warranties and covenants of the respective parties under this
Agreement and any Related Agreements are contained in the Indemnity and Escrow
Agreement.

Section 2.08.     DISSENTING SHARES.

               (a) Notwithstanding any provision of this Agreement to the
          contrary, any shares of Company Capital Stock held by a holder who has
          exercised and perfected appraisal rights to such shares in accordance
          with Delaware Law and who, as of the Effective Time, has not
          effectively withdrawn or lost such appraisal rights ("Dissenting
          Shares"), shall not be converted into or represent a right to receive
          the consideration for Company Capital Stock pursuant to Section 2.05,
          but the holder thereof shall only be entitled to such rights as are
          granted by Delaware Law.

               (b) Notwithstanding the provisions of subsection (a), if any
          holder of Dissenting Shares shall effectively withdraw or lose
          (through failure to perfect or otherwise) his or her appraisal rights,
          then, as of the later of the Effective Time or the occurrence of such
          event, such holder's shares shall automatically be converted into and
          represent only the right to receive the consideration for Company
          Capital Stock as provided in Section 2.05, without interest thereupon,
          upon surrender of the certificate representing such shares.



                                       17
<PAGE>   22

               (c) The Company shall give Parent (i) prompt notice of any
          written demand for appraisal received by the Company pursuant to the
          applicable provisions of Delaware Law, and (ii) the opportunity to
          participate in all negotiations and proceedings with respect to such
          demands. The Company shall not, except with the prior written consent
          of Parent, make any payment with respect to any such demands or offer
          to settle or settle any such demands. To the extent that Parent or the
          Company makes any payment or payments in respect of any Dissenting
          Shares, Parent shall be entitled to recover under the terms of Article
          IX hereof the aggregate amount by which such payment or payments
          exceed the aggregate consideration that otherwise would have been
          payable in respect of such shares.

Section 2.09.     NO FURTHER OWNERSHIP RIGHTS IN COMPANY CAPITAL STOCK.

         The Merger Consideration payable under Section 2.05 for the surrender
for exchange of the Company Capital Stock in accordance with the terms hereof,
shall be deemed to be full satisfaction of all rights pertaining to such shares
of Company Capital Stock other than the right to participate in the Earn-Out
payments, if any, and there shall be no further registration of transfers on the
records of the Surviving Corporation of shares of Company Capital Stock which
were outstanding immediately prior to the Effective Time. If, after the
Effective Time, Company Stock Certificates are presented to the Surviving
Corporation for any reason, they shall be canceled and exchanged as provided in
this Article II.

Section 2.10.     LOST, STOLEN OR DESTROYED CERTIFICATES.

         In the event any certificates evidencing shares of Company Capital
Stock shall have been lost, stolen or destroyed, Parent shall issue in exchange
for such lost, stolen or destroyed certificates, upon the making of an affidavit
of that fact by the holder thereof, the Merger Consideration, if any, as may be
required pursuant to Section 2.05 herein; provided, however, that Parent may, in
its discretion and as a condition precedent to the issuance thereof, require the
Stockholder who is the owner of such lost, stolen or destroyed certificates to
deliver a bond in such sum, not to exceed such Stockholder's Pro Rata Portion of
the Merger Consideration, as it may reasonably direct against any claim that may
be made against Parent with respect to the certificates alleged to have been
lost, stolen or destroyed.

Section 2.11.     FRACTIONAL SHARES.

         Parent shall not be required to issue any fractional shares. In lieu of
issuing such fractional shares, Parent shall pay to each Stockholder to which
such fractional shares would otherwise be issuable, an amount in cash equal to
the product of the fractional share otherwise issuable multiplied by the average
sale price per share of Parent Common Stock as determined under Section 2.05(c)
herein.

Section 2.12.     NO LIABILITY.

         Notwithstanding anything to the contrary in this Article II, none of
the Parent, the Surviving Corporation or any party hereto shall be liable to a
holder of shares of Company Capital Stock for any amount properly paid to a
public official pursuant to any applicable abandoned property, escheat or
similar law.


                                       18
<PAGE>   23

Section 2.13.     CLOSING DELIVERIES.

         At the Closing the parties to this Agreement shall deliver or cause to
be delivered the following documents and agreements:

               (a) The Company shall deliver to Parent:

                    (i) a copy of this Agreement, duly and validly executed by
               an executive officer of the Company;

                    (ii) a copy of the Indemnity and Escrow Agreement, duly and
               validly executed by the Principal Stockholders;

                    (iii) a copy of the Contingent Escrow Agreement duly and
               validly executed by the Principal Stockholders;

                    (iv) all consents, waivers, approvals and assignments listed
               on Schedule 3.06 of the Disclosure Schedule;

                    (v) a legal opinion from Cooley Godward LLP, dated as of the
               Closing Date, in the form of Exhibit H hereto;

                    (vi) Non-Competition Agreements in the form attached hereto
               as Exhibit J executed by the persons listed on Exhibit I hereto;

                    (vii) Personal Service Agreements executed by each of the
               persons listed on Exhibit K and as set forth therein;

                    (viii) Consent to Conversion of Preferred Stock executed by
               all holders of Preferred Stock;

                    (ix) a certificate, dated as of the Closing Date, executed
               on behalf of the Company by its Chief Executive Officer in the
               form of Exhibit L attached hereto;

                    (x) Certificate of Merger duly and validly executed by an
               executive officer of the Company; and

                    (xi) an Investment Letter executed by each of the Principal
               Stockholders.

               (b) Parent shall deliver to the Company and for the Stockholders
          as appropriate:

                    (i) a copy of this Agreement, duly and validly executed by
               an executive officer of the Company;


                                       19
<PAGE>   24


                    (ii) a certificate, dated as of the Closing Date, executed
               on behalf of Parent by its Chief Executive Officer or Chief
               Financial Officer in substantially the form attached hereto as
               Exhibit N;

                    (iii) a legal opinion from Morrison & Foerster LLP, legal
               counsel to Parent, dated as of the Closing Date substantially in
               the form of Exhibit O hereto;

                    (iv) a copy of the Indemnity and Escrow Agreement, duly and
               validly executed by an executive officer of Parent; and

                    (v) a copy of the Contingent Escrow Agreement, duly and
               validly executed by an executive officer of Parent.

               (c) Parent shall deliver to the Exchange Agent or Escrow Agent,
          as appropriate, cash and shares of Parent Common Stock in accordance
          with the terms and provisions contained in this Article II.

Section 2.14.     TAKING OF NECESSARY ACTION; FURTHER ACTION.

         If at any time after the Effective Time, any further action is
necessary or desirable to carry out the purposes of this Agreement and to vest
the Surviving Corporation with full right, title and possession to all assets,
property, rights, privileges, powers and franchises of the Company, Parent,
Merger Sub and the officers and directors of the Company, Parent and Merger Sub
are fully authorized in the name of their respective corporations or otherwise
to take, and will take, all such lawful and necessary action.

                                  ARTICLE III

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

         The Company hereby represents and warrants to Parent and Merger Sub,
subject to such exceptions as are specifically disclosed in the disclosure
schedule supplied by the Company and the Principal Stockholders to Parent and
Merger Sub (the "Disclosure Schedule") and dated as of the date hereof, that on
the date hereof and as of the Effective Time as though made at the Effective
Time as follows:

Section 3.01.     ORGANIZATION OF THE COMPANY.

         The Company is a corporation duly organized, validly existing and in
good standing under the laws of the State of Delaware. The Company has the
corporate power to own its properties and to carry on its business as now being
conducted. The Company is duly qualified or licensed to do business and in good
standing as a foreign corporation in the State of Texas and each other
jurisdiction in which it conducts business, except where the failure to so
qualify will not cause a Material Adverse Effect on the Company. The Company has
delivered a true and correct copy of its Certificate of Incorporation and
Bylaws, as amended to date, to Parent. Section 3.01 of the Disclosure Schedule
lists the directors and officers of the Company. The operations now being
conducted by the Company have not been conducted under any other names other
than ViroTex Corporation or Viro-Tex Corporation.


                                       20
<PAGE>   25

Section 3.02.     SUBSIDIARIES.

         The Company does not have, and has never had, any subsidiaries and does
not otherwise own, and has not otherwise owned, any shares in the capital of or
any interest in, or control, directly or indirectly, of any corporation,
partnership, association, joint venture or other business entity.

Section 3.03.     COMPANY CAPITAL STRUCTURE.

               (a) As of October 31, 1998, the authorized capital stock of the
          Company consisted of 15,000,000 shares of authorized Company Common
          Stock of which 667,997 shares were issued and outstanding and
          10,000,000 shares of authorized preferred stock consisting of 350,000
          shares of Series A Convertible Preferred Stock all of which are issued
          and outstanding; 384,616 shares of Series B Convertible Preferred
          Stock all of which were issued and outstanding; 340,000 shares of
          Series C Convertible Preferred Stock all of which were issued and
          outstanding; 1,000,000 shares of Series D Convertible Preferred Stock
          all of which were issued and outstanding; 1,566,668 shares of Series E
          Convertible Preferred Stock all of which were issued and outstanding;
          and 3,900,000 shares of Series F Convertible Preferred Stock of which
          1,100,000 shares were issued and outstanding; and 2,458,716 shares of
          undesignated preferred stock none of which was issued and outstanding.
          All outstanding shares of Company Capital Stock as of October 31, 1998
          were duly authorized, validly issued, fully paid and nonassessable and
          not subject to preemptive rights created by statute, the Certificate
          of Incorporation or Bylaws of the Company or any agreement to which
          the Company was a party or by which it was bound and were issued in
          compliance with federal and state securities laws. The Company has no
          other Company Capital Stock authorized, issued or outstanding.

               (b) As of the date hereof, there are 5,958,242 shares of Company
          Common Stock outstanding. The Company Common Stock is held by the
          persons with the domicile addresses and in the amounts set forth in
          Section 3.03(b) of the Disclosure Schedule. All unexercised Cash-Out
          Options that were outstanding as of October 31, 1998 have been
          exercised or, to the extent not exercised, will be assumed by Parent
          at Closing, and if exercised the holders of the Cash-Out Options have
          executed the form of option exercise ("Option Exercise Notice")
          attached hereto as Exhibit T. As of the date hereof, each of the
          holders of Preferred Stock have executed a "Consent to Conversion of
          Preferred Stock" in the form of Exhibit Q, each of which consents are
          in full force and effect and have not been revoked. All outstanding
          shares of Company Common Stock are duly authorized, validly issued,
          fully paid and nonassessable and not subject to preemptive rights
          created by statute, the Certificate of Incorporation or Bylaws of the
          Company or any agreement to which the Company is a party or by which
          it is bound and have been issued in compliance with federal and state
          securities laws. There are no declared or accrued unpaid dividends
          with respect to any shares of Company Capital Stock. The Company has
          no other Company Capital Stock authorized, issued or outstanding.


                                       21
<PAGE>   26

               (c) Except for the Company's 1991 Stock Option Plan, as amended
          (the "Plan"), the Company has never adopted or maintained any stock
          option plan or other plan providing for equity compensation of any
          person. The Company has reserved 1,575,000 shares of Company Common
          Stock for issuance to directors, employees, consultants and attorneys
          pursuant to the Plan, of which, as of the date hereof, 1,559,781
          shares have been issued and 983,000 shares are subject to outstanding
          Assumed Options. Section 3.03(c) of the Disclosure Schedule sets forth
          for each Assumed Option, the name of the holder of such Assumed
          Option, the domicile address of such holder, the number of shares of
          Company Common Stock subject to such Assumed Option, the exercise
          price of such Assumed Option, the vesting schedule for such Assumed
          Option, including the extent vested to date and whether the vesting of
          such Assumed Option will be accelerated by the transactions
          contemplated by this Agreement, and whether such Assumed Option is
          intended to qualify as an incentive stock option as defined in Section
          422 of the Code. Section 3.03(c) of the Disclosure Schedule also sets
          forth the name of the holder of any Company Capital Stock subject to
          vesting, the number of shares of Company Capital Stock subject to
          vesting and the vesting schedule for such Company Capital Stock,
          including the extent vested to date and whether the vesting of such
          shares of Company Capital Stock will be accelerated by the
          transactions contemplated by this Agreement. Except for the Assumed
          Options and the GulfStar Warrant, there are no options, warrants,
          calls, rights, commitments or agreements of any character, written or
          oral, to which the Company is a party or by which it is bound
          obligating the Company to issue, deliver, sell, repurchase or redeem,
          or cause to be issued, delivered, sold, repurchased or redeemed, any
          shares of Company Capital Stock or obligating the Company to grant,
          extend, accelerate the vesting of, change the price of, otherwise
          amend or enter into any such option, warrant, call, right, commitment
          or agreement. There are no outstanding or authorized stock
          appreciation, phantom stock, profit participation, or other similar
          rights with respect to Company Capital Stock. Other than the
          appointment of the Stockholders' Representatives as contemplated in
          the Indemnity and Escrow Agreement, there are no voting trusts,
          proxies, or other agreements or understandings with respect to the
          voting stock of the Company.

Section 3.04.     AUTHORITY.

         The Company has all requisite power and authority to enter into this
Agreement and any Related Agreements to which it is a party and to consummate
the transactions contemplated hereby and thereby. The execution and delivery of
this Agreement and any Related Agreements to which the Company is a party and
the consummation of the transactions contemplated hereby and thereby have been
duly authorized by all necessary corporate action on the part of the Company,
and no further action is required on the part of the Company to authorize the
Agreement and any Related Agreements to which it is a party and the transactions
contemplated hereby and thereby. Stockholders holding at least ninety-five
percent (95%) of the Company Capital Stock have approved this Agreement, the



                                       22
<PAGE>   27

Merger and the transactions contemplated hereby and thereby. This Agreement and
any Related Agreements to which the Company is a party have been duly executed
and delivered by the Company and, assuming the due authorization, execution and
delivery by the other parties hereto, constitutes the valid and binding
obligation of the Company, enforceable in accordance with its terms, except as
such enforceability may be limited by principles of public policy and subject to
the laws of general application relating to bankruptcy, insolvency and the
relief of debtors and to rules of law governing specific performance, injunctive
relief or other equitable remedies.

Section 3.05.     NO CONFLICT.

         The execution and delivery by the Company of this Agreement and any
Related Agreement to which the Company is a party and the consummation of the
transactions contemplated hereby and thereby will not conflict with or result in
any violation of or default under (with or without notice or lapse of time, or
both) or give rise to a right of termination, cancellation, modification or
acceleration of any obligation or loss of any benefit under (any such event, a
"Conflict") (i) any provision of the Certificate of Incorporation and Bylaws of
the Company, (ii) any mortgage, indenture, lease, contract or other agreement or
instrument, permit, concession, franchise or license to which the Company or any
of its properties or assets is subject, or (iii) any judgment, order, decree,
statute, law, ordinance, rule or regulation applicable to the Company or its
properties or assets.

Section 3.06.     CONSENTS.

         No consent, waiver, approval, order or authorization of, or
registration, declaration or filing with any court, administrative agency or
commission or other federal, state, county, local or other foreign governmental
authority, instrumentality, agency or commission ("Governmental Entity") or any
third party, including a party to any agreement with the Company (so as not to
trigger any Conflict), is required by or with respect to the Company in
connection with the execution and delivery of this Agreement and any Related
Agreement to which the Company is a party or the consummation of the
transactions contemplated hereby and thereby, except for such consents, waivers,
approvals, orders, authorizations, registrations, declarations and filings as
may be required under applicable securities laws hereby and thereby and filing
of the Certificate of Merger. The Company has obtained all consents, waivers and
approvals under any of the Contracts deemed reasonably appropriate or necessary
by Parent in connection with the Merger (all of such consents, waivers and
approvals are set forth in Section 3.06 of the Disclosure Schedule) so as to
preserve all rights of, and benefits to, the Company thereunder.

Section 3.07.     COMPANY FINANCIAL STATEMENTS.

         The Company has delivered to Parent the Company's audited balance
sheets as of December 31, 1997 and 1996, and related audited statements of
income, cash flow and stockholders' equity for the fiscal years then ended (the
"Year-End Financials") and (ii) the Company's unaudited balance sheet as of
September 30, 1998, and related unaudited statements of income, cash flow and
shareholders' equity for the three months and the nine months then ended (the
"Interim Financials"). The Year-End Financials and the Interim Financials are
correct in all material respects and have been prepared in accordance with GAAP



                                       23
<PAGE>   28

(except that the Interim Financials do not contain all footnotes and other
presentation items that may be required by GAAP). The Year-End Financials and
Interim Financials present fairly the financial condition, operating results and
cash flows of the Company as of the dates and during the periods indicated
therein, subject, in the case of the Interim Financials, to normal year-end
adjustments, which will not be material in amount or significance.

Section 3.08.     NO UNDISCLOSED LIABILITIES.

         The Company has no liability, indebtedness, obligation, expense, claim,
deficiency, guaranty or endorsement of any type, whether accrued, absolute,
contingent, matured, unmatured or other (whether or not required to be reflected
in financial statements in accordance with GAAP), which individually or in the
aggregate (i) has not been reflected in or reserved against in the Current
Balance Sheet, or (ii) has not arisen in the ordinary course of business
consistent with past practices prior to or subsequent to September 30, 1998, in
either case which amounts exceed $25,000 in the aggregate; provided, however,
all liabilities for accrued but unpaid vacation or time off for employees or
other benefits or liabilities payable to such employees upon termination of
employment have been accrued and reflected on the Current Balance Sheet and, in
any event, total severance benefits payable to the Company's employees and
former employees shall not exceed $425,000.00 at the Closing Date.

Section 3.09.     PRODUCTS/PRODUCT LIABILITY.

               (a) Each of the products produced, developed or sold by the
          Company (excluding products developed by the Company but produced and
          sold by third parties under license or agreement or by third parties
          to which such products were sold, provided, that the Company has been
          fully indemnified by such third parties for any and all liabilities
          relating thereto, which indemnification rights will continue in full
          force and effect after the Effective Time) (the "Company Products")
          is, and at all times up to and including the sale thereof by the
          Company has been (a) in compliance in all material respects with all
          applicable federal, state, and local laws and regulations, and (b)
          conforms in all material respects to any promises or affirmations of
          fact made on the container or label for such product or in connection
          with its sale.

               (b) To the knowledge of the Company, there is no design defect
          with respect to the Company Products. At the time of sale to the
          public, each Company Product contained adequate warnings, presented in
          a reasonably prominent manner, in accordance with applicable laws,
          rules and regulations and current industry practice with respect to
          its contents and use.

               (c) The Company's External Analgesic Product, Benzocaine Canker
          Sore Product, Topical Antibiotic Product, Wound Wash Product, Wart
          Removal Product and BEMA-Dyclonine Canker Sore Disc (if such product
          is launched in the OTC market), as currently formulated, satisfy and
          conform and will satisfy and conform with (i) each OTC drug monograph
          applicable to such products and their intended uses, as promulgated by
          the Food and Drug Administration ("FDA"), (ii) the active ingredients
          allowed by the applicable OTC monographs both as to the specified
          concentration established for each ingredient and as to the specified



                                       24
<PAGE>   29

          dosage form set forth in the applicable OTC monograph or, if no dosage
          or concentration is specified, in amounts and forms that conform to
          current industry standards. Such products, excluding the
          BEMA-Dyclonine Canker Sore Disk if not launched in the OTC market,
          will not require the filing of a new drug application with the FDA
          under current laws and regulations.

               (d) The Company has no knowledge of any liability, or of any
          facts or circumstances reasonably likely to give rise to any
          litigation against the Company, arising out of or relating to any
          injury to individuals or property as a result of the ownership,
          possession, or use of any product developed, manufactured or sold by
          the Company. The Company has provided the Parent with true and correct
          copies of its standard product warranties, and all Contracts to which
          it is a party, performance of which by the Company has not been
          completed, and which include nonstandard product warranties.

Section 3.10.     LOANS, NOTES, CASH, ACCOUNTS RECEIVABLE AND ACCOUNTS PAYABLE.

         The Company has provided Parent with an accurate and complete breakdown
and aging of all accounts receivable, notes receivable and other receivables of
the Company as of the Balance Sheet Date. All receivables (a) have arisen only
from bona fide transactions in the ordinary course of business consistent with
past practice, (b) represent valid obligations, and (c) are current and are
expected to be collectible in the aggregate face amounts thereof without any
counterclaim or set-off when due, except to the extent of the normal allowance
for doubtful accounts with respect to accounts receivable that are computed in a
manner consistent with GAAP and as reflected in the Balance Sheet or with
respect to receivables arising subsequent to the Balance Sheet Date, the books
and records of the Company, and (d) are owned by the Company free of all Liens.
No discount or allowance from any receivable has been made or agreed to (other
than customary payment discounts in the ordinary course of business consistent
with past practice), and none represents billings prior to actual sale of goods
or provision of services. Accounts payable of the Company reflected on the
Balance Sheet and all accounts payable arising after the Balance Sheet Date
arose, and have arisen, from bona fide transactions. The Company has $1,000,000
in cash after deducting the Company Payment Amount. The Company has paid all
costs and obligations customarily paid by the Company through the date hereof in
accordance with past practice.

Section 3.11.     PROJECTIONS.

         The financial projections relating to the Company products identified
in Section 3.16(h) (excluding the Wart Removal Product and BEMA-Dyclonine Canker
Sore Disc) and delivered to Parent as set forth in Exhibit G hereto, were made
in good faith and are based upon assumptions that the Company believes were
reasonable, and the Company is not aware of any fact or set of circumstances
that would lead it to believe that such projections are incorrect or misleading
in any material respect.


                                       25
<PAGE>   30


Section 3.12.     ABSENCE OF CERTAIN CHANGES.

         Since the Balance Sheet Date, the Company has conducted its business in
the ordinary course consistent with past practices and, except pursuant to or as
contemplated under this Agreement or any Related Agreements, there has not been
any Material Adverse Effect and there is no condition or development or
contingency of any kind existing that could reasonably be expected to result in
a Material Adverse Effect on the business of the Company. Without limiting the
foregoing, except as set forth in Section 3.12 of the Disclosure Schedule, since
the Balance Sheet Date, there has not been, occurred or arisen:

               (a) any issuance or sale or authorization of the issuance or sale
          of any shares of Company Capital Stock or other securities of the
          Company or options or warrants relating to shares of Company Capital
          Stock or other securities of the Company;

               (b) any declaration, setting aside or payment of any dividend or
          other distribution with respect to any shares of Company Capital
          Stock, or any direct or indirect repurchase, redemption, retirement,
          purchase or other acquisition by the Company of any outstanding shares
          of capital stock or other securities of, or other ownership interests
          in, the Company;

               (c) any amendment of any material term of any outstanding
          security of the Company;

               (d) any incurrence, assumption or guarantee by the Company of any
          indebtedness for borrowed money, other than in the ordinary course of
          business, exceeding $10,000;

               (e) any creation or assumption by the Company of any Lien on any
          material asset of the Company;

               (f) any making of any loan, advance or capital contributions to
          or investment in any Person;

               (g) any material damage, destruction or other casualty loss
          affecting the business or assets of the Company not covered by
          insurance;

               (h) any transaction or commitment made, or any contract or
          agreement entered into, by the Company relating to its assets or
          business (including the acquisition or disposition of any assets) or
          any relinquishment by the Company of any contract or other right
          (direct or indirect, whether alleged, contingent or otherwise), in
          either case, material to the Company, taken as a whole;

               (i) any sale, assignment, transfer or grant of any license or
          sublicense with respect to any Intellectual Property Right or other
          intangible asset used or useful in the business of the Company;




                                       26

<PAGE>   31

               (j) any incurrence or payment of any material obligation or
          liability (absolute, accrued or contingent) other than current
          liabilities shown on the Balance Sheet and current liabilities
          incurred since the Balance Sheet Date in the ordinary course of
          business consistent with past practice;

               (k) any change in any method of accounting or accounting practice
          by the Company, except for any such change after the date hereof
          required by reason of a concurrent change in GAAP;

               (l) any (i) employment, deferred compensation, severance,
          retirement or other similar agreement entered into with any director,
          officer or employee of the Company (or any amendment to any such
          existing agreement), (ii) grant of any severance or termination pay to
          any director, officer or employee of the Company, or (iii) change in
          compensation or other benefits payable to any director, officer or
          employee of the Company pursuant to any severance or retirement plans
          or policies thereof;

               (m) any labor dispute, other than routine individual grievances,
          or any activity or proceeding by a labor union or representative
          thereof to organize any employees of the Company, which employees were
          not subject to a collective bargaining agreement at the Balance Sheet
          Date, or any lockouts, strikes, slowdowns, work stoppages or threats
          thereof by or with respect to any employees of the Company;

               (n) any tax election by the Company or any settlement or
          compromise of any income tax liability by the Company;

               (o) any other material occurrence, event, incident, action,
          failure to act, or transaction outside the ordinary course of business
          involving the Company; and

               (p) the Company has not committed to any of the foregoing.

Section 3.13.     TAX MATTERS.

               (a) Definitions. For purposes of this Agreement, the following
          definitions shall apply:

                    (i) The term "Taxes" shall mean all taxes, however,
               denominated, including any interest, penalties or other additions
               to tax that may become payable in respect thereof, imposed by any
               federal, territorial, state, local or foreign government or any
               agency or political subdivision of any such government, which
               taxes shall include, without limiting the generality of the
               foregoing, all income or profits (including, but not limited to,
               federal income taxes and state income taxes), payroll and
               employee withholding, social security, sales and use, ad valorem,
               excise, franchise, gross receipts, business license, occupation,
               real and personal property, stamp, environmental, transfer,
               workers' compensation and any other taxes, tariffs or
               governmental charges, and other obligations of the same or of a
               similar nature to any of the foregoing, which the Company is
               required to pay, withhold or collect.


                                       27
<PAGE>   32

                    (ii) The term "Returns" shall mean all reports, estimates,
               declarations of estimated tax, information statements and returns
               relating to, or required to be filed in connection with, any
               Taxes, including information returns or reports with respect to
               backup withholding and other payments to third parties.

               (b) Returns Filed and Taxes Paid. All Returns required to be
          filed by or on behalf of the Company have been duly filed on a timely
          basis, or requests for extensions to file such Returns have been
          timely filed, granted and have not expired, and such Returns are true,
          complete and correct in all material respects. All material Taxes due
          with respect to periods ending on or prior to the Closing Date,
          whether or not required to be shown on a Return to be due, have been
          or will be paid in full on a timely basis. The Company has withheld
          and paid over all Taxes required to have been withheld and paid over,
          and complied with all information reporting and backup withholding
          requirements, including maintenance of required records with respect
          thereto, in connection with amounts paid or owing to any employee,
          creditor, independent contractor, or other third party. There are no
          liens on any of the assets of the Company with respect to Taxes, other
          than liens for Taxes not yet due and payable or for Taxes that the
          Company is contesting in good faith through appropriate proceedings
          and for which appropriate reserves have been established.

               (c) Tax Reserves. The reserves for Taxes reflected on the Current
          Balance Sheet are adequate for the payment of all Taxes payable by the
          Company for all taxable periods and portions thereof accrued through
          the date of the Current Balance Sheet, and such reserves will continue
          to be established in accordance with past practice with respect to
          Taxes payable for any taxable period or portion thereof ending on or
          prior to the Closing Date.

               (d) Returns Furnished. The Company has made available to Parent
          true and complete copies of (i) relevant portions of income tax audit
          reports, statements of deficiencies, closing or other similar
          agreements received by or on behalf of the Company relating to Taxes
          and (ii) all federal and state income or franchise tax returns for the
          Company for all periods ending on or after December 31, 1995. The
          Company has never been a member of an affiliated group filing
          consolidated returns. The Company does not do business in or derive
          income from any state, local, territorial or foreign taxing
          jurisdiction other than those for which all Returns have been
          furnished to Parent.

               (e) Tax Deficiencies; Audits; Statutes of Limitations. The
          Returns of the Company have never been audited by a government or
          taxing authority, nor, to the knowledge of the Company, is any such
          audit in process, pending or threatened. No deficiencies exist or have
          been asserted or, to the Company's knowledge, are expected to be
          asserted with respect to Taxes of the Company, and the Company has not



                                       28
<PAGE>   33

          received and does not expect to receive notice that it has not filed a
          Return or paid Taxes required to be filed or paid by it. There is no
          action or proceeding pending for the assessment or collection of Taxes
          to which the Company is a party, nor has such an action been asserted
          or threatened against the Company or any of its assets. No waiver or
          extension of any statute of limitations is in effect with respect to
          Taxes or Returns of the Company.

               (f) Tax Sharing Agreements. The Company is not and has never been
          a party to any agreement providing for sharing, indemnification or
          allocation of Taxes, whether formal or informal.

               (g) Tax Elections and Special Tax Status. The Company is not a
          party to any safe harbor lease within the meaning of Section 168(f)(8)
          of the Code, as in effect prior to amendment by the Tax Equity and
          Fiscal Responsibility Act of 1982. The Company is not, and has not
          been at any time during the five year period ending on the Closing
          Date, a United States real property holding corporation within the
          meaning of Section 897(c)(2) of the Code. The Company has not given a
          consent under Section 341(f) of the Code. The Company will not be
          required to include in a taxable period ending after the Closing Date
          taxable income attributable to income that economically accrued in a
          taxable period ending on or prior to the Closing Date as a result of
          the installment method of accounting, the completed contract method of
          accounting, the cash method of accounting or otherwise. The Company
          has not agreed, nor is it required, to make any adjustment under Code
          Section 481(a) by reason of a change in accounting method or
          otherwise. The Company has not participated in an international
          boycott as defined in Code Section 999. The Company does not have a
          permanent establishment in any foreign country, as defined in any
          applicable Tax treaty or convention between the United States of
          America and such foreign country, and the Company is not a party to
          any joint venture, partnership or other agreement, contract or
          arrangement (either in writing or verbally, formally or informally)
          which could be treated as a partnership for federal income tax
          purposes.

               (h) Tax Basis and Tax Attributes. The Company Tax Return for the
          1997 fiscal year, contained, to the extent required to be included,
          accurate and complete descriptions of the Company's tax basis in its
          assets, current and accumulated earnings and profits, tax carryovers,
          and tax elections affecting the Company. The Company has no net
          operating losses or other tax attributes presently subject to
          limitation under Code Sections 382, 383, or 384.

               (i) Compensation. The disallowance of a deduction under Section
          162(m) of the Code will not apply to any amount paid or payable by the
          Company under any contract, stock plan, benefit plan, program,
          arrangement or understanding currently in effect. Any amount or other
          entitlement that could be received as a result of any of the
          transactions contemplated by this Agreement by any employee, officer
          or director of the Company under any employment, severance or
          termination agreement, other compensation arrangement or benefit plan
          currently in effect would not be characterized as an "excess parachute
          payment" (as such term is defined in Section 280G(b)(1) of the Code).



                                       29
<PAGE>   34

Section 3.14.     RESTRICTIONS ON BUSINESS ACTIVITIES.

         There is no agreement (non-compete or otherwise), commitment, judgment,
injunction, order or decree to which the Company is a party or otherwise binding
upon the Company which has or may reasonably be expected to have the effect of
prohibiting or impairing any business practice of the Company, any transfer of
property (tangible or intangible) by the Company or the conduct of business by
the Company. Without limiting the foregoing, the Company has not entered into
any agreement under which the Company is restricted from selling, licensing or
otherwise distributing any of its technology or products to or providing
services to, customers or potential customers or any class of customers, in any
geographic area, during any period of time or in any segment of the market.

Section 3.15.     TITLE OF PROPERTIES; ABSENCE OF LIENS AND ENCUMBRANCES; 
                  CONDITION OF EQUIPMENT.

               (a) The Company does not own any real property and has never
          owned any real property. Section 3.15(a) of the Disclosure Schedule
          sets forth a list of all real property currently leased by the
          Company, the name of the lessor, the date of the lease and each
          amendment thereto and, with respect to any current lease, the
          aggregate annual rental and/or other fees payable under any such
          lease. All such current leases are in full force and effect, are valid
          and effective in accordance with their respective terms, and there is
          not, under any of such leases, any existing default or event of
          default (or event which with notice or lapse of time, or both, would
          constitute a default)

               (b) The Company has good and valid title to, or, in the case of
          leased properties and assets, valid leasehold interests in, all of its
          tangible properties and assets, real, personal and mixed, used or held
          for use in its business, free and clear of any Liens, except (i) as
          reflected in the Current Balance Sheet, (ii) Liens for Taxes not yet
          due and payable and (iii) landlord Liens.

               (c) Section 3.15(c) of the Disclosure Schedule lists all items of
          equipment (the "Equipment") owned or leased by the Company and such
          Equipment is (i) adequate for the conduct of the business of the
          Company as currently conducted and (ii) in good operating condition,
          regularly and properly maintained, subject to normal wear and tear.

               (d) The Company has sole and exclusive ownership, free and clear
          of any Liens, of all customer files and other customer information
          relating to the Company's current and former customers (the "Customer
          Information"), except to the extent that such customers have rights of
          access to their own Customer Information. No person other than the
          Company possesses any claims or rights with respect to use of the
          Customer Information.



                                       30

<PAGE>   35

Section 3.16.     INTELLECTUAL PROPERTY.

               (a) For the purposes of this Agreement, the following terms have
          the following definitions:

                    (i) "Intellectual Property" shall mean any or all of the
               following and all rights in, arising out of, or associated
               therewith: (A) all United States and foreign patents and
               applications therefor and all reissues, divisions, renewals,
               extensions, provisionals, continuations and continuations-in-part
               thereof; (B) all inventions (whether patentable or not),
               invention disclosures, improvements, trade secrets, proprietary
               information, know how, technology, technical data and customer
               lists, and all documentation relating to any of the foregoing;
               (C) all copyrights, copyright registrations and applications
               therefor and all other rights corresponding thereto throughout
               the world; (D) all mask works, mask work registrations and
               applications therefor, (E) all industrial designs and any
               registrations and applications therefor throughout the world; (F)
               all trade names, logos, common law trademarks and service marks;
               trademark and service mark registrations and applications
               therefor and all goodwill associated therewith throughout the
               world; (G) all databases and data collections and all rights
               therein throughout the world; (H) all computer software including
               all source code, object code, firmware, development tools, files,
               records and data, all media on which any of the foregoing is
               recorded, all Web addresses, sites and domain names, (I) any
               similar, corresponding or equivalent rights to any of the
               foregoing and (J) all documentation related to any of the
               foregoing.

                    (ii) "Company Intellectual Property" shall mean any
               Intellectual Property that is owned by or exclusively licensed to
               the Company.

                    (iii) "Registered Intellectual Property" shall mean all
               United States, international and foreign: (A) patents, patent
               applications (including provisional applications); (B) registered
               trademarks, applications to register trademarks, intent-to-use
               applications, or other registrations or applications related to
               trademarks; (C) registered copyrights and applications for
               copyright registration; (D) any mask work registrations and
               applications to register mask works; and (E) any other Company
               Intellectual Property that is the subject of an application,
               certificate, filing, registration or other document issued by,
               filed with, or recorded by, any state, government or other public
               legal authority.

               (b) Section 3.16(b) of the Disclosure Schedule lists all
          Registered Intellectual Property owned by, or filed in the name of,
          the Company (the "Company Registered Intellectual Property"), and
          lists any proceedings or actions before any court, tribunal (including
          the United States Patent and Trademark Office (the "PTO") or
          equivalent authority anywhere in the world) related to any of the
          Company Registered Intellectual Property.


                                       31
<PAGE>   36

               (c) Each item of Company Intellectual Property is free and clear
          of any Liens. The Company (i) is the exclusive owner of all trademarks
          and trade names used in connection with the operation or conduct of
          the business of the Company, including the sale of any products or
          technology or the provision of any services by the Company, and (ii)
          owns exclusively, and has good title to, all copyrighted works that
          are Company products or other works of authorship that the Company
          otherwise purports to own.

               (d) To the extent that any Intellectual Property has been
          developed or created by any person other than the Company for which
          the Company has, directly or indirectly, paid, the Company has a
          written agreement with such person with respect thereto and the
          Company thereby has the right to become the owner of or to obtain an
          exclusive license with respect to all such Intellectual Property by
          operation of law or by valid assignment.

               (e) To the knowledge of the Company, any non-proprietary software
          used by the Company (other than commercially available off the shelf
          software), is free from significant programming errors and operates in
          substantial conformity with its user documentation and other
          descriptions and standards applicable thereto provided by the Company,
          and such software does not contain any known virus, timer, clock,
          counter or other limiting design, instruction or routine, that would
          erase data, programming or become inoperable or otherwise incapable of
          being used in the full manner for which it was designed and created
          nor has the Company been informed that the non-proprietary software
          has any such problems.

               (f) The licenses, sublicenses, agreements, contracts and
          permissions (as amended to date) listed in Schedule 3.16(f) include
          all licenses, sublicenses, agreements, contracts and permissions with
          respect to any Intellectual Property licensed to or used by the
          Company. With respect to each such license, sublicense, agreement,
          contract or permission:

                    (i) the license, sublicense, agreement, or permission
               covering the item is legal, valid, binding, enforceable, and in
               full force and effect;

                    (ii) the license, sublicense, agreement, or permission will
               continue to be legal, valid, binding, enforceable, and in full
               force and effect on identical terms following the Effective Date;

                    (iii) to the Company's knowledge (other than with respect to
               the Company), no party to the license, sublicense, agreement, or
               permission is in breach or default, and no event has occurred
               which with notice or lapse of time would constitute a breach or
               default or permit termination, modification, or acceleration
               thereunder;

                    (iv) to the Company's knowledge (other than with respect to
               the Company), no party to the license, sublicense, agreement, or
               permission has repudiated any provision thereof;


                                       32

<PAGE>   37

                    (v) to the Company's knowledge (other than with respect to
               Company Intellectual Property), the underlying item of the
               Intellectual Property is not subject to any outstanding judgment,
               order, decree, stipulation, injunction, or charge; and 

                    (vi) to the Company's knowledge (other than with respect to
               Company Intellectual Property), no charge, complaint, action,
               suit, proceeding, hearing, investigation, claim, or demand is
               pending, or to the knowledge of the Company (including, employees
               with responsibility for Intellectual Property matters) is
               threatened, which challenges the legality, validity, or
               enforceability of the underlying item of the Intellectual
               Property.

               (g) Except as set forth in Section 3.16(g), the Company has not
          transferred ownership of or granted any license of or right to use or
          authorized the retention of any rights to use any Intellectual
          Property that is or was Company Intellectual Property, to any other
          person.

               (h) The Company Intellectual Property constitutes all the
          Intellectual Property used in or reasonably necessary to the conduct
          of its business as it currently is conducted, and, to the Company's
          knowledge, as is currently contemplated to be conducted with respect
          to the Acne Product, External Analgesic Product, Benzocaine Canker
          Sore Product, Topical Antibiotic Product, Wound Wash Product, Wart
          Removal Product, BEMA-Dyclonine Canker Sore Disc, BEMA-Dyclonine
          Strips and BEMA-Nicotine, including, without limitation, the design,
          development, manufacture, use, import and sale of such products,
          technology or services.

               (i) Section 3.16(i) of the Disclosure Schedule lists all
          contracts, licenses and agreements between the Company and any other
          person (other than off the shelf software) wherein or whereby the
          Company has agreed to, or assumed, any obligation or duty to warrant,
          indemnify, reimburse, hold harmless, guaranty or otherwise assume or
          incur any obligation or liability or provide a right of rescission
          with respect to the infringement or misappropriation by the Company or
          such other person of the Intellectual Property of any person other
          than the Company.

               (j) To the Company's knowledge, the operation of the business of
          the Company as it currently is conducted or is currently contemplated
          to be conducted with respect to the Acne Product, External Analgesic
          Product, Benzocaine Canker Sore Product, Topical Antibiotic Product,
          Wound Wash Product, Wart Removal Product, BEMA-Dyclonine Canker Sore
          Disc, BEMA-Dyclonine Strips and BEMA-Nicotine, including but not
          limited to the Company's design, development, use, import, manufacture
          and sale of such products, technology or services does not infringe or
          misappropriate the Intellectual Property of any person, violate the
          rights of any person (including rights to privacy or publicity), or
          constitute unfair competition or trade practices under the laws of any
          jurisdiction, and the Company has not received notice from any person
          claiming that such operation or any act, product, technology or



                                       33
<PAGE>   38

          service (including products, technology or services currently under
          development) of the Company infringes or misappropriates the
          Intellectual Property of any person or constitutes unfair competition
          or trade practices under the laws of any jurisdiction (nor is the
          Company aware of any basis therefor).

               (k) All necessary registration, maintenance and renewal fees in
          connection with the Company Registered Intellectual Property have been
          paid and all necessary documents and certificates in connection with
          the Company Registered Intellectual Property have been filed with the
          relevant patent, copyright, trademark or other authorities in the
          United States or foreign jurisdictions, as the case may be, for the
          purposes of maintaining such Registered Intellectual Property. Except
          as set forth in Section 3.16(k)) of the Disclosure Schedule, there are
          no actions that must be taken by the Company within sixty (60) days of
          the Closing Date, including the payment of any registration,
          maintenance or renewal fees or the filing of any documents,
          applications or certificates for the purposes of maintaining,
          perfecting or preserving or renewing any Company Intellectual
          Property. Except as set forth in Section 3.16(k) of the Disclosure
          Schedule, for each product or technology of the Company that
          constitutes or includes a copyrightable work, the Company has
          registered the copyright in the latest version of such work with the
          U.S. Copyright Office. In each case in which the Company has acquired
          any Company Registered Intellectual Property rights from any person,
          the Company has obtained a valid and enforceable assignment sufficient
          to irrevocably transfer all rights in such Company Registered
          Intellectual Property (including the right to seek past and future
          damages with respect to such Intellectual Property) to the Company
          and, to the maximum extent provided for by, and in accordance with,
          applicable laws and regulations, the Company has recorded each such
          assignment with the relevant governmental authorities, including the
          PTO, the U.S. Copyright Office, or their respective equivalents in any
          relevant foreign jurisdiction, as the case may be.

               (l) There are no contracts, licenses or agreements between the
          Company and any other person with respect to Company Intellectual
          Property under which there is any dispute known to the Company
          regarding the scope of such agreement or performance under such
          agreement including with respect to any payments to be made or
          received by the Company thereunder.

               (m) To the knowledge of the Company, no person is infringing or
          misappropriating any Company Intellectual Property. 

               (n) The Company has taken all reasonable steps that are required
          to protect the Company's rights in confidential information and trade
          secrets of the Company or provided by any other person to the Company.
          Without limiting the foregoing, the Company has, and enforces, a
          policy requiring each employee, consultant and contractor to execute
          proprietary information, confidentiality and assignment agreements
          substantially in the Company's standard forms as set forth, in
          Schedule 3.16(n), and all current and former employees, consultants
          and contractors of the Company have executed such an agreement. To the
          Company's knowledge, no employee of the Company is subject to any
          secrecy or noncompetition agreement or any agreement or restriction of



                                       34
<PAGE>   39

          any kind that would impede in any material way the ability of such
          employee to carry out fully all activities of such employee in
          furtherance of the business of the Company as currently operated after
          the Closing Date. To the Company's knowledge, no third party has
          claimed that any person employed by or affiliated with the Company has
          violated or may be violating any of the terms or conditions of his
          past employment, noncompetition or nondisclosure agreement with such
          third party; or disclosed or may be disclosing or utilized or may be
          utilizing any trade secret or proprietary information or documentation
          of such third party or interfered or may be interfering in the
          employment relationship between such third party and any of its
          present or former employees.

               (o) No Company Intellectual Property or product, technology or
          service of the Company is subject to any proceeding or outstanding
          decree, order, judgment, agreement or stipulation that restricts in
          any manner the use, transfer or licensing thereof by the Company or
          may affect the validity, use or enforceability of such Company
          Intellectual Property.

               (p) No (i) product, technology, service or publication of the
          Company (ii) material published or distributed by the Company or (iii)
          conduct or statement of the Company constitutes obscene material, a
          defamatory statement or material, false advertising or otherwise
          violates any law or regulation, except where any such violation will
          not have a Material Adverse Effect on the Company.

               (q) All material software products used by the Company (other
          than off the shelf software) will record, store, process, calculate
          and present calendar dates falling on and after (and if applicable,
          spans of time including) January 1, 2000, and will calculate any
          information dependent on or relating to such dates in the same manner,
          and with the same functionality, data integrity and performance, as
          the products record, store, process, calculate and present calendar
          dates on or before December 31, 1999, or calculate any information
          dependent on or relating to such dates.

Section 3.17.      AGREEMENTS, CONTRACTS AND COMMITMENTS.

               (a) Except as set forth in Section 3.17(a) of the Disclosure
          Schedule, the Company is not a party to nor is it bound by:

                    (i) any employment or consulting agreement, contract or
               commitment with an employee or individual consultant or
               salesperson or consulting or sales agreement, contract or
               commitment with a firm or other organization;

                    (ii) any agreement or plan, including, without limitation,
               any stock option plan, stock appreciation rights plan or stock
               purchase plan, any of the benefits of which will be increased, or
               the vesting of benefits of which will be accelerated, by the
               occurrence of any of the transactions contemplated by this
               Agreement or the value of any of the benefits of which will be
               calculated on the basis of any of the transactions contemplated
               by this Agreement;



                                       35
<PAGE>   40

                    (iii) any fidelity or surety bond or completion bond;

                    (iv) any lease of personal property having a value in excess
               of $10,000 individually or $25,000 in the aggregate;

                    (v) any agreement, contract or commitment containing any
               covenant limiting the freedom of the Company to engage in any
               line of business or to compete with any person,

                    (vi) any agreement, contract or commitment relating to
               capital expenditures and involving future payments in excess of
               $25,000 individually or $50,000 in the aggregate;

                    (vii) any agreement, contract or commitment relating to the
               disposition or sale of assets or any interest in any business
               enterprise outside the ordinary course of the Company's business;

                    (viii) any mortgages, indentures, loans or credit
               agreements, security agreements or other agreements or
               instruments relating to the borrowing of money or extension of
               credit;

                    (ix) any purchase order or contract for the purchase of
               materials involving in excess of $10,000 individually or $50,000
               in the aggregate;

                    (x) any construction contracts;

                    (xi) any dealer, distribution, joint marketing or
               development agreement;

                    (xii) any sales representative, original equipment
               manufacturer, value added, remarketer or other agreement for
               distribution of the Company's products or services;

                    (xiii) any written indemnification agreements between the
               Company and its directors and officers other than indemnification
               obligations set forth in the Company's Certificate of
               Incorporation or Bylaws;

                    (xiv) any agreement granting a third-party a right of first
               offer or right of first refusal for any products of the Company
               or any products developed by the Company in the future; or

                    (xv) any other agreement, contract or commitment that
               involves $25,000 individually or $50,000 in the aggregate or is
               not cancelable without penalty within thirty (30) days.

               (b) The Company is in compliance in all material respects with
          and has not breached, violated or defaulted under, or received notice
          that it has breached, violated or defaulted under, any of the terms or
          conditions of any agreement, contract, covenant, instrument, lease,



                                       36
<PAGE>   41

          license or commitment to which the Company is a party or by which
          either is bound (collectively a "Contract"), nor is the Company aware
          of any event that would constitute such a breach, violation or default
          with the lapse of time, giving of notice or both. Assuming due
          execution by the other parties thereto, each Contract is in full force
          and effect and the Company is not subject to any default thereunder,
          nor to the knowledge of the Company is any party obligated to the
          Company pursuant to such Contract subject to any default thereunder.
          Following the Closing, the Company will be permitted to exercise all
          of the Company's rights under the Contracts without the payment of any
          additional amounts or consideration other than ongoing fees, royalties
          or payments which the Company would otherwise be required to pay had
          the transactions contemplated by this Agreement not occurred. The
          Company has not received notice from CEP Holdings, Inc., or its
          assignees, that it intends to curtail promoting, marketing or selling
          the Viractin(R) product line.

Section 3.18.     INTERESTED PARTY TRANSACTIONS.

         No officer, director or Stockholder of the Company (nor, to the actual
knowledge of the Company, any ancestor, sibling, descendant or spouse of any of
such persons, or any trust, partnership or corporation in which any of such
persons has or has had an interest), has or has had, directly or indirectly, (i)
an interest in any entity that furnished or sold, or furnishes or sells,
services, products or technology that the Company furnishes or sells, or
proposes to furnish or sell, or (ii) any interest in any entity that purchases
from or sells or furnishes to the Company, any goods or services, or (iii) a
beneficial interest in any Contract; provided, that ownership of no more than
one percent (1%) of the outstanding voting stock of a publicly traded
corporation shall not be deemed to be an "interest in any entity" for purposes
of this Section 3.18.

Section 3.19.     GOVERNMENTAL AUTHORIZATION.

         Section 3.19 of the Disclosure Schedule accurately lists each consent,
license, permit, grant or other authorization issued to the Company by a
Governmental Entity (i) pursuant to which the Company currently operates or
holds any interest in any of its properties or (ii) which is required for the
operation of its business as currently conducted or the holding of any such
interest (herein collectively called "Company Authorizations"), except for any
immaterial authorizations. The Company Authorizations are in full force and
effect and constitute all Company Authorizations required to permit the Company
to operate or conduct its business as currently conducted or presently
contemplated or to hold any interest in its properties or assets, except for any
Authorizations that if not obtained would not have a Material Adverse Effect on
the Company.

Section 3.20.     REGULATORY REPORTS.

         The Company, and to the Company's knowledge, all licensees or
co-development partners of the Company, has filed all material reports,
registrations and statements, together with any amendments required to be made
with respect thereto, that they were required to file in respect to any drug
delivery product or other product developed by the Company (other than the
Viractin(R) product line since its sale to CEP Holdings, Inc.) (the "Products")
in the last five (5) year period with any federal, state, local or foreign



                                       37
<PAGE>   42

governmental, quasi-governmental or regulatory department, authority or agency,
including, without limitation, the FDA or the Federal Trade Commission
(collectively, "Regulatory Agencies"), and has paid all fees or assessments due
and payable in connection therewith. No Regulatory Agency has initiated any
proceeding or investigation into the business or operations of the Company or
the Products in the last five (5) year period, nor has the Company or the
Company's licensee or co-development partners initiated any such proceeding.
There is no unresolved violation, criticism or exception by any Regulatory
Agency with respect to any report or statement relating to an examination of the
Products.

Section 3.21.     LITIGATION.

         There is no action, suit or proceeding of any nature pending, or, to
the Company's knowledge, threatened, against the Company its properties or any
of its officers or directors, nor, to the knowledge of the Company, is there any
reasonable basis therefor. There is no investigation pending or, to the
Company's knowledge, threatened, against the Company, its properties or any of
its officers or directors (nor, to the knowledge of the Company, is there any
reasonable basis therefor) by or before any Governmental Entity. No Governmental
Entity has at any time challenged or questioned the legal right of the Company
to conduct its operations as presently or previously conducted.

Section 3.22.     MINUTE BOOKS.

         The minutes of the Company made available to counsel for Parent are the
only minutes of the Company and contain summaries, accurate in all material
respects, of all meetings of the Board of Directors (or committees thereof) of
the Company and its shareholders or actions by written consent since the time of
incorporation of the Company.

Section 3.23.     ENVIRONMENTAL MATTERS.

         The Company is not in material violation of any Environmental Laws
applicable to it or its properties, or any material limitations, restrictions,
conditions, standards, obligations or timetables contained in any Environmental
Laws. No notice or action alleging such violation is pending or, to the
Company's knowledge, threatened, and no past or present condition or practice of
the businesses conducted by the Company would prevent continued compliance with
any Environmental Permits or give rise to any common law or statutory liability
or otherwise from the basis of any claim, action or proceeding with respect to
the Company involving any Hazardous Substances. The Company has no Environmental
Liability.

Section 3.24.     BROKERS' AND FINDERS' FEES AND THIRD PARTY EXPENSES.

         Except for a fee to be paid pursuant to the terms of an agreement dated
November 4, 1997 between the Company and to Volpe Brown Whelan & Company (the
"Volpe Agreement"), which will be paid by the Company at Closing (the "Volpe
Brown Fee"), the Company has not incurred, nor will it incur, directly or
indirectly, any liability for brokerage or finders' fees or agents' commissions
or any similar charges in connection with the Agreement or any transaction
contemplated hereby. The Company has terminated the Volpe Agreement. The Company
has provided Parent with a written statement of the Estimated Third Party
Expenses.


                                       38
<PAGE>   43

Section 3.25.     EMPLOYEE BENEFIT PLANS AND COMPENSATION.

               (a) The following terms shall have the meanings set forth below:

                    (i) "Affiliate" for purposes of this Section 3.25, shall
               mean any other person or entity under common control with the
               Company within the meaning of Section 414(b), (c), (m) or (o) of
               the Code and the regulations issued thereunder;

                    (ii) "Company Employee Plan" shall mean any plan, program,
               policy, practice, contract, agreement or other arrangement
               providing for compensation, severance, termination pay, deferred
               compensation, performance awards, stock or stock-related awards,
               fringe benefits or other employee benefits or remuneration of any
               kind, whether written or unwritten, funded or unfunded, including
               without limitation, each "employee benefit plan," within the
               meaning of Section 3(3) of ERISA which is or has been maintained,
               contributed to, or required to be contributed to, by the Company
               or any Affiliate for the benefit of any Employee, or with respect
               to which the Company or any Affiliate has or may have any
               liability or obligation;

                    (iii) "COBRA" shall mean the Consolidated Omnibus Budget
               Reconciliation Act of 1985, as amended;

                    (iv) "DOL" shall mean the Department of Labor;

                    (v) "Employee" shall mean any current or former employee,
               consultant or director of the Company or any Affiliate;

                    (vi) "Employee Agreement" shall mean each management,
               employment, severance, consulting, relocation or other agreement,
               contract or understanding between the Company or any Affiliate
               and any Employee;

                    (vii) "ERISA" shall mean the Employee Retirement Income
               Security Act of 1974, as amended; and

                    (viii) "FMLA" shall mean the Family Medical Leave Act of
               1993, as amended;

                    (ix) "IRS" shall mean the Internal Revenue Service;

                    (x) "PBGC" shall mean the Pension Benefit Guaranty
               Corporation; and

                    (xi) "Pension Plan" shall mean each Company Employee Plan
               which is an "employee pension benefit plan," within the meaning
               of Section 3(2) of ERISA.



                                       39
<PAGE>   44

               (b) Schedule. Section 3.25(b) of the Disclosure Schedule contains
          an accurate and complete list of each Company Employee Plan and each
          Employee Agreement under each Company Employee Plan or Employee
          Agreement. The Company does not have any plan or commitment to
          establish any new Company Employee Plan or Employee Agreement, to
          modify any Company Employee Plan or Employee Agreement (except to the
          extent required by law or to conform any such Company Employee Plan or
          Employee Agreement to the requirements of any applicable law, in each
          case as previously disclosed to Parent in writing, or as required by
          this Agreement), or to enter into any Company Employee Plan or
          Employee Agreement.

               (c) Termination of Employee Agreements. The Company has
          terminated each of the Employee Agreements set forth on Schedule
          3.25(c) and has received a release in full of any liability in
          connection with such Employee Agreement, except with respect to the
          payment of the severance obligations required under such Employee
          Agreement, which obligations are set forth in the Disclosure Schedule.
          The provisions of the Employee Agreements relating to confidentiality,
          non-competition and invention assignment will continue in full force
          and effect for the period of time set forth in each Employee
          Agreement.

               (d) Documents. The Company has provided to Parent: (i) correct
          and complete copies of all documents embodying each Company Employee
          Plan and each Employee Agreement including (without limitation) all
          amendments thereto and all related trust documents; (ii) the three (3)
          most recent annual reports (Form Series 5500 and all schedules and
          financial statements attached thereto), if any, required under ERISA
          or the Code in connection with each Company Employee Plan; (iii) if
          the Company Employee Plan is funded, the most recent annual and
          periodic accounting of Company Employee Plan assets; (iv) the most
          recent summary plan description together with the summary(ies) of
          material modifications thereto, if any, required under ERISA with
          respect to each Company Employee Plan; (v) all material written
          agreements and contracts relating to each Company Employee Plan,
          including, but not limited to, administrative service agreements and
          group insurance contracts; (vi) all communications material to any
          Employee or Employees relating to any Company Employee Plan and any
          proposed Company Employee Plans, in each case, relating to any
          amendments, terminations, establishments, increases or decreases in
          benefits, acceleration of payments or vesting schedules or other
          events which would result in any liability to the Company; (vii) all
          correspondence to or from any governmental agency directly relating to
          any Company Employee Plan; (viii) all COBRA forms and related notices
          currently in use by the Company or under which the Company is
          currently obligated; (ix) all policies in force pertaining to
          fiduciary liability insurance covering the fiduciaries for each
          Company Employee Plan; (x) all discrimination tests for each Company
          Employee Plan for the most recent plan year; and (xi) all registration
          statements, annual reports (Form 10-K and all attachments thereto) and
          prospectuses prepared in connection with each Company Employee Plan.


                                       40
<PAGE>   45

               (e) Employee Plan Compliance. (i) The Company has performed in
          all material respects all obligations required to be performed by it
          under, is not in default or violation of, and has no knowledge of any
          default or violation by any other party to each Company Employee Plan,
          and each Company Employee Plan has been established and maintained in
          all material respects in accordance with its terms and in compliance
          with all applicable laws, statutes, orders, rules and regulations,
          including but not limited to ERISA or the Code; (ii) no "prohibited
          transaction," within the meaning of Section 4975 of the Code or
          Sections 406 and 407 of ERISA, and not otherwise exempt under Section
          408 of ERISA, has occurred with respect to any Company Employee Plan;
          (iii) there are no actions, suits or claims pending, or, to the
          knowledge of the Company, threatened or reasonably anticipated (other
          than routine claims for benefits) against any Company Employee Plan or
          against the assets of any Company Employee Plan; (iv) each Company
          Employee Plan can be amended, terminated or otherwise discontinued
          after the Effective Time in accordance with its terms, without
          liability to Parent, the Company or any Affiliate (other than ordinary
          administration expenses); (v) there are no audits, inquiries or
          proceedings pending or, to the knowledge of the Company or any
          Affiliates, threatened by the IRS or DOL with respect to any Company
          Employee Plan; and (vi) neither the Company nor any Affiliate is
          subject to any penalty or tax with respect to any Company Employee
          Plan under Section 502(i) of ERISA or Sections 4975 through 4980 of
          the Code.

               (f) No Pension Plans. Neither the Company nor any Affiliate has
          ever maintained, established, sponsored, participated in, or
          contributed to, any Pension Plan.

               (g) No Post-Employment Obligations. No Company Employee Plan
          provides, or reflects or represents any liability to provide, retiree
          life insurance, retiree health or other retiree employee welfare
          benefits to any person for any reason, except as may be required by
          COBRA or other applicable statute or except for severance or other
          benefits set forth in the Disclosure Schedule, and the Company has
          never represented, promised or contracted (whether in oral or written
          form) to any Employee (either individually or to Employees as a group)
          or any other person that such Employee(s) or other person would be
          provided with retiree life insurance, retiree health or other retiree
          employee welfare benefit, except to the extent required by statute.

               (h) COBRA. Neither the Company nor any Affiliate has, prior to
          the Effective Time, violated any of the health care continuation
          requirements of COBRA, the requirements of FMLA or any similar
          provisions of state law applicable to its Employees.

               (i) Effect of Transaction. The execution of this Agreement and
          the consummation of the transactions contemplated hereby will not
          (either alone or upon the occurrence of any additional or subsequent
          events) constitute an event under any Company Employee Plan, Employee
          Agreement, trust or loan that will or may result in any payment
          (whether of severance pay or otherwise), acceleration, forgiveness of
          indebtedness, vesting, distribution, increase in benefits or
          obligation to fund benefits with respect to any Employee.



                                       41
<PAGE>   46

               (j) Employment Matters. Schedule 3.25(j) sets forth a true and
          complete list of the names, title, annual salaries and other
          compensation of all officers of the Company and all other employees of
          the Company. The Company: (i) is in compliance with all applicable
          foreign, federal, state and local laws, rules and regulations
          respecting employment, employment practices, terms and conditions of
          employment and wages and hours, in each case, with respect to
          Employees, except where such noncompliance would not have a Material
          Adverse Effect on the Company; provided, however, that Schedule
          3.25(j) shall disclose any such laws, rules and regulations which, to
          the Company's actual knowledge, it is not in compliance whether or not
          material; (ii) is not liable for any arrears of wages or any penalty
          for failure to comply with the foregoing; and (iii) is not overdue on
          any payment to any trust or other fund governed by or maintained by or
          on behalf of any governmental authority, with respect to unemployment
          compensation benefits, social security or other benefits or
          obligations for Employees (other than routine payments to be made in
          the normal course of business and consistent with past practice).
          There are no pending or, to the knowledge of the Company, threatened
          or reasonably anticipated claims or actions against the Company under
          any worker's compensation policy or long-term disability policy.

               (k) Labor. No work stoppage or labor strike against the Company
          is pending, or to the knowledge of the Company, threatened or
          reasonably anticipated. The Company does not know of any activities or
          proceedings of any labor union to organize any Employees. There are no
          actions, suits, claims, labor disputes or grievances pending, or, to
          the knowledge of the Company, threatened or reasonably anticipated
          relating to any labor, safety or discrimination matters involving any
          Employee, including, without limitation, charges of unfair labor
          practices or discrimination complaints. Neither the Company nor any of
          its subsidiaries has engaged in any unfair labor practices within the
          meaning of the National Labor Relations Act. The Company is not
          presently, nor has it been in the past, a party to, or bound by, any
          collective bargaining agreement or union contract with respect to
          Employees and no collective bargaining agreement is being negotiated
          by the Company.

Section 3.26.     INSURANCE.

         Section 3.26 of the Disclosure Schedule lists all insurance policies
and fidelity bonds covering the assets, business, equipment, properties,
operations, employees, officers and directors of the Company or any Affiliate.
There is no claim by the Company or any Affiliate pending under any of such
policies or bonds as to which coverage has been questioned, denied or disputed
by the underwriters of such policies or bonds and the Company has made no claims
under such policies within the last five years. All premiums due and payable
under all such policies and bonds have been paid, and the Company and its
Affiliates are otherwise in material compliance with the terms of such policies
and bonds (or other policies and bonds providing substantially similar insurance
coverage). The Company does not have knowledge of any threatened termination of,
or premium increase with respect to, any of such policies.


                                       42
<PAGE>   47

Section 3.27.     COMPLIANCE WITH LAWS.

         The Company has complied with, is not in violation of, and has not
received any notices of violation with respect to, any foreign, federal, state
or local statute, law or regulation, except where the failure to comply will not
have a Material Adverse Effect on the Company.

Section 3.28.     WARRANTIES; INDEMNITIES.

         Except as set forth in Section 3.28 of the Disclosure Schedule and
warranties implied by law, the Company has not given any warranties or
indemnities relating to products or technology developed, sold or services
rendered by the Company.

Section 3.29.     CONFLICTS OF INTEREST.

         None of the Company or any officer, employee, agent or other Person
acting on behalf of the Company has, directly or indirectly, given or agreed to
give any money, gift or similar benefit (other than legal price concessions to
customers in the ordinary course of business) to any customer, supplier,
employee or agent of a customer or supplier, or official or employee of any
Governmental Authority or other Person who was or is in a position to help or
hinder the business of the Company (or assist in connection with any actual or
proposed transaction) that (i) might subject the Company to any damage or
penalty in any proceeding or investigation, (ii) if not given in the past, could
have resulted in a Material Adverse Effect on the Company, or (iii) if not
continued in the future, could result in a Material Adverse Effect on the
Company.

Section 3.30.     COMPLETE COPIES OF MATERIALS.

         The Company has delivered or made available true and complete copies of
each document (or summaries of same) that has been requested specifically in
writing by Parent or its counsel.

Section 3.31.     REPRESENTATIONS COMPLETE.

         No representation or warranty made by the Company, nor any statement
made in the Disclosure Schedule or certificate furnished by the Company pursuant
to this Agreement or any Related Agreements contains or will contain, any untrue
statement of a material fact or omits or will omit to state any material fact
necessary in order to make the statements contained herein or therein not
misleading.


                                       43
<PAGE>   48

                                   ARTICLE IV

             REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB

         Parent and Merger Sub hereby represent and warrant to the Company that
on the date hereof and as of the Effective Time as though made at the Effective
Time as follows:

Section 4.01.     ORGANIZATION, STANDING AND POWER.

         Parent is a corporation duly organized, validly existing and in good
standing under the laws of the State of Delaware. Merger Sub is a corporation
duly organized, validly existing and in good standing under the laws of
Delaware. Each of Parent and Merger Sub has the corporate power to own its
properties and to carry on its business as now being conducted and is duly
qualified or licensed to do business and is in good standing in each
jurisdiction in which the failure to be so qualified or licensed would have a
material adverse effect on the ability of Parent and Merger Sub to consummate
the transactions contemplated hereby.

Section 4.02.     AUTHORITY.

         Each of Parent and Merger Sub has all requisite corporate power and
authority to enter into this Agreement and any Related Agreements to which it is
a party and to consummate the transactions contemplated hereby and thereby. The
execution and delivery of this Agreement and any Related Agreements to which it
is a party and the consummation of the transactions contemplated hereby and
thereby will be duly authorized by all necessary corporate action on the part of
Parent and Merger Sub at and as of the Closing Date. This Agreement and any
Related Agreements to which Parent and Merger Sub are parties have been duly
executed and delivered by Parent and Merger Sub and, assuming the due
authorization, execution and delivery by the other parties hereto, constitute
the valid and binding obligations of Parent and Merger Sub, enforceable in
accordance with their terms, except as such enforceability may be limited by
principles of public policy and subject to the laws of general application
relating to bankruptcy, insolvency and the relief of debtors and rules of law
governing specific performance, injunctive relief or other equitable remedies.

Section 4.03.     BROKERS' AND FINDERS FEES.

         Neither Parent nor Merger Sub has incurred, nor will it incur, directly
or indirectly, any liability for brokerage or finders' fees or agents'
commissions or any similar charges in connection with this Agreement or any
transaction contemplated hereby.

Section 4.04.     NO CONFLICT.

         The execution and delivery of this Agreement and any Related Agreements
to which it is a party and, the consummation of the transactions contemplated
hereby will not Conflict with or give rise to a Conflict under (i) any provision
of the Certificate of Incorporation, as amended, and Bylaws of Parent or Merger
Sub, (ii) any mortgage, indenture, lease, contract or other agreement or
instrument, permit, concession, franchise or license to which Parent or any of
its respective properties or assets are subject and which has been filed as an



                                       44
<PAGE>   49

exhibit to Parent's filings under the Securities Act or the Exchange Act, or
(iii) any judgment, order, decree, statute, law, ordinance, rule or regulation
applicable to Parent or Merger Sub or its properties or assets, except where
such Conflict will not have a Material Adverse Effect on the business, assets
(including intangible assets), financial condition or results of operations of
Parent and Merger Sub taken as a whole.

Section 4.05.     CONSENTS.

         No consent, waiver, approval, order or authorization of, or
registration, declaration or filing with, any Governmental Entity, or any third
party is required by or with respect to Parent or Merger Sub in connection with
the execution and delivery of this Agreement and any Related Agreements to which
Parent or Merger Sub is a party or the consummation of the transactions
contemplated hereby or thereby, except for such consents, waivers, approvals,
orders, authorizations, registrations, declarations and filings as may be
required under applicable securities laws hereby or thereby and such consents,
waivers, approvals, orders, authorizations, registrations, declarations and
filings which, if not obtained or made, would not have a Material Adverse Effect
on the business, assets (including intangible assets), financial condition or
results of operations of Parent and its subsidiaries taken as a whole.

Section 4.06.     COMPLIANCE WITH LAWS.

         Parent has complied with, is not in violation of, and has not received
any notices of violation with respect to, any foreign, federal, state or local
statute, law or regulation, except where the failure to comply will not have a
Material Adverse Effect on Parent.

Section 4.07.     SEC REPORTS.

         The Parent's Annual Report on Form 10-K for the year ended December 31,
1997 and each form, report, schedule, registration statement and definitive
proxy statement filed by Parent with the SEC subsequent thereto (as such
documents have been amended prior to the date hereof, the "Parent SEC Reports"),
as of their respective dates, complied in all material respects with the
applicable requirements of the Securities Act and the Exchange Act and the rules
and regulations thereunder. None of the Parent SEC Reports, as of their
respective dates, contained or contains any untrue statement of material fact or
omits to state a material fact required to be stated therein or necessary to
make the statements therein, in light of the circumstances under which they were
made, not misleading. The financial statements of Parent included in such
reports comply as to form in all material respects with applicable accounting
requirements and with the published rules and regulations of the SEC with
respect thereto, have been prepared in accordance with GAAP (except as may be
indicated in the notes to such financial statements and, in the case of
unaudited statements, as permitted by Form 10-Q of the SEC, and except that
unaudited financial statements may not contain footnotes and are subject to
year-end audit adjustments) and fairly present the financial position of Parent
as and at the date thereof and the results of its operations and cash flows for
the periods then ended. Since December 31, 1997, neither Parent nor any of its
subsidiaries has incurred any liabilities or obligations of any nature (whether
absolute, accrued, fixed, contingent, liquidated or unliquidated, known or



                                       45
<PAGE>   50

unknown) except liabilities, obligations and contingencies (a) which are
reflected in the consolidated balance sheet of Parent at December 31, 1997, or
(b) which (i) were incurred in the ordinary course of business since December
31, 1997 and consistent with past practices, (ii) are disclosed in the Parent
SEC Reports filed since December 31, 1997, or (iii) would not individually or in
the aggregate have a Material Adverse Effect on Parent. Since December 31, 1997,
except as described in any Parent SEC Reports, there has been no change in any
of the significant accounting policies, practices or procedures of Parent except
changes resulting from changes in accounting pronouncements of the Financial
Accounting Standards Boards or changes in applicable laws. Parent has timely
filed all SEC Reports required to be filed by Parent and is eligible to register
shares for resale on Form S-3.

Section 4.08.     FINANCIAL CAPABILITY.

         Parent will have on the Closing Date and immediately prior to the
Effective Time, funds and authorized and unissued shares of Parent Common Stock
sufficient to consummate the Merger, fund the escrow for the earn-out and
otherwise consummate the transactions contemplated hereby.

Section 4.09.     PARENT CAPITAL STRUCTURE.

               (a) As of the date hereof, the authorized capital stock of the
          Parent consists of 25,000,000 shares of authorized Parent Common Stock
          of which 11,322,560 shares are issued and outstanding; and 5,000,000
          shares of authorized preferred stock consisting of 200,000 shares
          designated as Series A Preferred Stock none of which is issued and
          outstanding; and 4,800,000 shares of undesignated preferred stock none
          of which is issued and outstanding. All outstanding shares of Parent
          Common Stock are duly authorized, validly issued, fully paid and
          nonassessable. Parent has reserved 2,631,578 shares of Parent Common
          Stock for issuance upon conversion of Parent's Subordinated
          Convertible Notes due 2004. The Parent has also reserved 300,000
          shares of Parent Common Stock for issuance to employees of Parent
          pursuant to the Parent's 1997 Employee Stock Purchase Plan, of which
          7,708 shares have been issued. The Parent has no other Parent Capital
          Stock authorized, issued or outstanding.

               (b) The Parent has reserved 2,500,000 shares of Parent Common
          Stock for issuance to officers, directors and key employees, employees
          of Parent and subsidiaries of Parent pursuant to Parent's Amended and
          Restated Performance Stock Option Plan, of which, as of the date
          hereof, 731,965 shares have been issued, and 1,136,904 shares are
          subject to outstanding, unexercised options. The Parent has reserved
          150,000 shares of Parent Common Stock for issuance to non-employees of
          Parent pursuant to the Parent's Nonqualified Stock Option Plan, of
          which, as of the date hereof, 43,500 shares have been issued and
          34,480 shares are subject to outstanding, exercised options.



                                       46
<PAGE>   51

                                    ARTICLE V

                              ADDITIONAL AGREEMENTS

Section 5.01.     EXPENSES.

         Whether or not the Merger is consummated, all fees and expenses
incurred in connection with the Merger including, without limitation, all legal,
accounting, financial advisory, consulting and all other fees and expenses of
third parties ("Third Party Expenses") incurred by a party in connection with
the negotiation and effectuation of the terms and conditions of this Agreement
and the transactions contemplated hereby or thereby, shall be the obligation of
the respective party incurring such fees and expenses; provided, that, if the
Merger is consummated, Parent and the Company agree that the Company will pay
the Volpe Brown Fee, all accounting fees incurred by the Company and up to
$50,000 of additional Third Party Expenses incurred by the Company (the "Company
Payment Amount"), and the Stockholders shall pay all Third Party Expenses in
excess of the Company Payment Amount through a reduction of the cash paid at
Closing.

Section 5.02.     PUBLIC DISCLOSURE.

         Unless otherwise required by law, no disclosure (whether or not in
response to an inquiry) of the subject matter of this Agreement shall be made by
any party hereto unless approved by the other parties hereto prior to release.

Section 5.03.     S-8 REGISTRATION.

         In the event Parent's current Registration Statement on Form S-8 does
not contain a sufficient number of shares to cover the shares of the Parent
Common Stock issuable upon exercise of the Assumed Options, promptly after the
Closing Date, Parent shall prepare and file with the Securities and Exchange
Commission an amendment to Parent's Registration Statement on Form S-8 (or
another appropriate form) to register the necessary number of shares of Parent
Common Stock subject to Assumed Options.

Section 5.04.     REGISTRATION STATEMENT.

               (a) Within ten (10) business days after the Closing Date, Parent
          shall file a registration statement on Form S-3 (the "Registration
          Statement") to cover the resale of the shares of Parent Common Stock
          issued or to be issued to the Stockholders pursuant to the terms of
          this Agreement, including, without limitation, all shares of Parent
          Common Stock issuable upon the occurrence of an Earn-Out Event, the
          Parent Warrant and shares of Parent Common Stock issuable upon
          exercise of the Parent Warrant (the "Registered Shares"). Parent shall
          use its best efforts to cause such Registration Statement to be
          declared effective within sixty (60) days after the filing date.
          Parent shall use its best efforts to keep such Registration Statement
          continuously effective, supplemented and amended for a period of two
          years after the Closing Date. For purposes of this Section 5.04 and
          Section 5.05 the term "Stockholders" shall include Permitted
          Assignees.


                                       47
<PAGE>   52

               (b) Parent will bear the costs of all Registration Expenses. For
          the purposes hereof, "Registration Expenses" shall mean all expenses
          incident to Parent's preparation and filing of the Registration
          Statement, including, without limitation, all registration and filing
          fees, fees and expenses of compliance with federal securities laws or
          state blue sky laws, printing expenses, messenger and delivery
          expenses, fees and disbursements of custodians and fees and
          disbursements of counsel for Parent and all independent certified
          public accountants, and other persons retained by Parent (but not of
          Stockholder's counsel).

Section 5.05. REGISTRATION PROCEDURES.

         In connection with the registration and sale of the Registered Shares
the Company will:

               (a) prepare and file with the Commission the Registration
          Statement as set forth above;

               (b) provide to each Stockholder a copy of the Registration
          Statement and related Prospectus, including each preliminary
          Prospectus, if any, and each amendment and supplement thereto;

               (c) use its best efforts to register or qualify the Registered
          Shares under such other securities or blue sky laws of such
          jurisdictions as each Stockholder may reasonably request and do any
          and all other acts and things that may be reasonably necessary or
          advisable to enable such Stockholder to consummate the disposition in
          such jurisdictions of the Registered Shares owned by such Stockholder;
          provided, however, that Parent will not be required to (i) qualify
          generally to do business in any jurisdiction where it would not
          otherwise be required to qualify but for this subsection (c), (ii)
          subject itself to taxation in any such jurisdiction, or (iii) consent
          to general service of process in any such jurisdiction;

               (d) Upon the occurrence of any event that would cause the
          Registration Statement (i) to contain any untrue statement of a
          material fact or omit to state a material fact required to be stated
          therein or necessary to make the statements therein not misleading or
          (ii) to be not effective and useable for resale of the Registered
          Shares during the period that such Registration Statement is required
          to be effective and useable, Parent upon knowledge of such an event,
          shall as promptly as practicable file an amendment to the Registration
          Statement, in the case of clause (i), correcting any such misstatement
          or omission, and, in the case of either clause (i) or (ii), use its
          best efforts to cause such amendment to be declared effective and such
          Registration Statement to become useable as soon as practicable
          thereafter;

               (e) Notwithstanding anything to the contrary in this Section
          5.05, Parent may prohibit offers and sales of the Registered Shares
          pursuant to the Registration Statement at any time if (A) (i) it is in
          possession of material non-public information, (ii) the Board of
          Directors of Parent determines based on advice of counsel (which
          counsel shall be experienced in securities laws matters) that such
          prohibition is necessary in order to avoid a requirement to disclose



                                       48
<PAGE>   53

          such material non-public information, and (iii) the Board of Directors
          of Parent determines in good faith that disclosure of such material
          non-public information would not be in the best interests of Parent
          and its stockholders, or (B) (i) Parent has made a public announcement
          relating to an acquisition or business combination transaction
          including Parent and/or one or more of its subsidiaries that is
          material to Parent and its subsidiaries taken as a whole, and (ii) the
          Board of Directors of Parent determines in good faith that offers and
          sales of the Registered Shares pursuant to the Registration Statement
          prior to the consummation of such transaction (or such earlier date as
          the Board of Directors shall determine) is not in the best interests
          of Parent and its stockholders (the period during which any such
          prohibition of offers and sales of Registered Shares pursuant to the
          Registration Statement is in effect pursuant to clause (A) or (B) of
          this subsection 5.05(e) is referred to herein as a "Suspension
          Period"); provided, however, that the Suspension Period may not occur
          any more frequently than once in any twelve month period. A Suspension
          Period shall commence on and include the date on which Parent provides
          written notice to Stockholders covered by the Registration Statement
          that offers and sales of Registered Shares cannot be made thereunder
          in accordance with this Section 5.05 and shall end three Business Days
          after the earlier to occur of (x) the date on which such material
          information is disclosed to the public or ceases to be material or
          Parent is able to so comply with its disclosure obligations and
          Commission requirements, or (y) 45 days after written notice is
          provided by Parent to the Stockholders of such Suspension Period. Each
          notice shall state to the extent, if any, as is practicable, an
          estimate of the expected duration of the Suspension Period;

               (f) Parent shall provide to each Stockholder a copy of the
          proposed plan of distribution to be included in the Registration
          Statement and each Stockholder shall furnish to Parent such
          information regarding the distribution of its Registered Shares as is
          required by law to be disclosed in the Registration Statement (the
          "Requisite Information") prior to effecting any sale pursuant to such
          Registration Statement. Each Stockholder as to which any Registration
          Statement is being effected agrees prior to effecting any sale of the
          Registered Shares thereunder to furnish promptly to Parent all
          information required to be disclosed in order to make any Requisite
          Information previously furnished to Parent by such Stockholder not
          materially misleading or necessary to cause such Registration
          Statement not to omit a material fact with respect to such Stockholder
          necessary in order to make the statements therein not misleading;

               (g) Each Stockholder agrees by acquisition of such Registered
          Shares that, upon receipt of any notice from Parent of the existence
          of any fact of the kind described in subsections 5.05(d) and (e)
          hereof (an "Amendment Notice"), such Stockholder will forthwith
          discontinue disposition of Registered Shares until such Stockholder's
          receipt of (i) copies of the supplemented or amended Prospectus
          contemplated by subsection 5.05(d) hereof, or until counsel for Parent
          shall have determined that such disclosure is not required due to
          subsequent events, (ii) notice in writing from Parent that the use of
          the Prospectus may be resumed, (iii) copies of any additional or
          supplemental filings with respect to the Prospectus, or (iv) the
          expiration of the Suspension Period. In the event Parent shall give



                                       49
<PAGE>   54

          any such notice, the time period regarding the filing of the
          Registration Statement set forth in subsection 5.04(a) hereof shall be
          extended by the number of days during the period from and including
          the date of the giving of such notice pursuant to subsection 5.05(e)
          hereof to and including the date when each Stockholder covered by such
          Registration Statement shall have received the copies of the
          supplemented or amended Prospectus contemplated by this subsection
          (g); and

               (h) Parent agrees to use its best efforts to cause the Registered
          Shares covered by the Registration Statement to be registered with or
          approved by such other governmental agencies or authorities as may be
          necessary to enable the Stockholders thereof to consummate the
          disposition of such Registered Shares, subject to the proviso
          contained in subsection (c) above, and cause all Registered Shares to
          be listed on each securities exchange or national quotation system on
          which Parent's Common Stock is then listed by no later than the date
          on which the Registration Statement is declared effective.

Section 5.06.     INDEMNIFICATION.

         With respect to the Registration Statement, the Stockholders and Parent
shall be bound by the indemnification obligations set forth in the Investment
Letter.

Section 5.07.     EXCULPATION FOR DIRECTOR LIABILITY.

         Parent shall, and Parent shall cause the Company to, keep in effect
provisions of the Certificate of Incorporation and Bylaws of the Company
providing for exculpation of director liability and indemnification of
directors, officers and agents of the Company to the fullest extent permitted
under the Delaware Code, which provisions shall not be amended except as
required by applicable law. Parent shall, and Parent shall cause the Company to,
keep in effect and cause compliance with the terms and conditions of the
indemnification agreements, if any between the Company and each of its directors
and officers in effect as of the date of this Agreement.

Section 5.08.     LEASE TERMINATION.

               (a) The Company shall no later than May 31, 1999 have either (i)
          terminated its leases of the buildings located at 4200 Research Forest
          Drive, The Woodlands, Texas and 8701 New Trails, Suite A, The
          Woodlands, Texas (collectively, the "Property Leases"), or (ii)
          subleased each of the Property Leases for at least that rental rate
          that will fully discharge the obligations and liabilities of the
          Company under the Property Leases; provided, however, that such
          sublease(s) shall terminate no later than November 19, 1999.
          Notwithstanding the foregoing, the parties agree and acknowledge that
          it is the intent of the Company to relocate the Company's operations
          to Fort Collins, Colorado and in connection therewith, commencing on
          the Closing Date, the Company intends to begin the process of moving
          all or part of the laboratory equipment, furniture, office equipment,
          supplies and other personal property from the Company's offices to the
          Parent's offices in Fort Collins, Colorado.


                                       50
<PAGE>   55

               (b) The Principal Stockholders agree that the Principal
          Stockholders shall be liable for all lease payments and obligations
          arising out of the Property Leases for the period after May 31, 1999
          and further agree that if the actions of the Company in the relocation
          of all or part of the laboratory equipment, furniture, office
          equipment, supplies and other personal property from the Company's
          offices to the Parent's offices in Fort Collins, Colorado and the
          winding down of the Company's operations in The Woodlands, Texas shall
          cause or be deemed to cause a default or breach under the Property
          Leases, then the liability (other than liability by reason of damage
          caused to the facilities during the moving process) associated with
          such default or breach shall be the liability of the Principal
          Stockholders and be subject to the indemnification obligations of the
          Principal Stockholders as set forth in the Indemnity and Escrow
          Agreement. Any liability of the Principal Stockholders arising under
          this Section 5.08(b) shall not be subject to the Floor (as defined in
          the Indemnity and Escrow Agreement).

               (c) Prior to or concurrent with the Closing, the Company shall
          have obtained a waiver from the landlord under the Property Leases to
          the effect that the landlord acknowledges that the Company is moving
          its operations to the Parent's office in Fort Collins, Colorado and
          waiving any default arising from the removal and relocation of any
          personal property of the Company located at the Property Lease
          locations.

Section 5.09.     PRODUCTS LIABILITY INSURANCE.

         Parent hereby covenants and agrees that it will use its best efforts to
maintain, or cause the Company to maintain, tail products liability insurance
coverage in amounts no less than currently maintained by Company (and with a
deductible no greater than the Company's deductible) to cover products liability
claims with respect to Company Products sold prior to the Closing until the
expiration of the representation and warranty in Section 3.09 of the Agreement.
If solely through the fault of Parent or Company, but not otherwise, such
product liability insurance is not maintained, then the representation and
warranty in Section 3.09 shall expire automatically as of the last day of such
insurance coverage.

                                   ARTICLE VI

                            SURVIVAL, INDEMNIFICATION

         The covenants, agreements, representations and warranties of the
parties hereto contained in this Agreement or in any certificate or other
writing delivered pursuant hereto or in connection herewith shall survive the
Closing and shall expire and be of no further force or effect at 12:00 a.m. on
November 24, 1999. Notwithstanding the previous sentence, (i) the covenants and
warranties contained in Section 3.25(c) shall survive for the period of time
specified therein; (ii) the covenant contained in Section 5.08 shall continue
until the termination of the leases referred to therein; and (iii) the
covenants, agreements, representations and warranties contained in Sections
3.09, 3.13, 3.23, 5.07 and 5.09 shall survive until expiration of the statute of
limitations applicable to the matters covered thereby (giving effect to any
waiver, mitigation or extension thereof). Notwithstanding the preceding
sentence, any covenant, agreement, representation or warranty in respect of



                                       51
<PAGE>   56

which indemnity may be sought under this Agreement shall survive the time at
which it would otherwise terminate pursuant to the preceding sentence, if
written notice of the inaccuracy or breach thereof giving rise to such right of
indemnity shall have been given to the party against whom such indemnity may be
sought prior to such time.

                                  ARTICLE VII

                               GENERAL PROVISIONS

Section 7.01.     NOTICES.

         All notices, requests and other communications to any party hereunder
shall be in writing (including facsimile transmissions) and shall be deemed to
have been given if delivered personally or by commercial messenger or courier
service, or mailed by registered or certified mail (return receipt requested) or
sent via facsimile (with acknowledgment of complete transmission) to the parties
at the following addresses (or at such other address for a party as shall be
specified by like notice):

               (a) if to Parent, to:

                    Atrix Laboratories, Inc.
                    2975 Midpoint Drive
                    Fort Collins, Colorado 80252
                    Attention: Dr. Charles P. Cox
                    Vice President, New Business Development
                    Telephone: (970) 482-5868
                    Facsimile: (970) 482-9765

                    with a copy to:

                    Morrison & Foerster LLP
                    5200 Republic Plaza
                    370 17th Street
                    Denver, Colorado  80202
                    Attention:  Warren L. Troupe
                    Telephone:  (303) 592-1500
                    Facsimile:  (303) 592-1510

               (b) if to the Company or the Principal Stockholders, to:

                    ViroTex Corporation
                    4200 Research Forest Drive, Suite 350
                    The Woodlands, Texas  77381
                    Attention:  Jeffrey M. Soinski
                    President and CEO
                    Telephone:  (281) 292-7671
                    Facsimile:  (281) 292-6697



                                       52
<PAGE>   57



                     with a copy to:

                     Cooley Godward LLP
                     4365 Executive Drive
                     Suite 1100
                     San Diego, CA 92121
                     Attention:  Frederick T. Muto
                                 Barbara L. Borden
                     Telephone:  (619) 550-6000
                     Facsimile:  (619) 453-3555

               (c) If to the Stockholders' Representatives, to:

                     Anthony A. Brown
                     114 Golden Shadow Circle
                     The Woodlands, Texas  77381
                     Telephone:  (281) 367-9718
                     Facsimile:  (281) 298-9798

                     William T. Mullaney
                     Chairman
                     Ventures Medical, L.P.
                     16945 Northchase Drive, Suite 2150
                     Houston, Texas  77060
                     Telephone:  (281) 873-5748 x12
                     Facsimile:  (281) 873-5950

         Notice so given shall be deemed given and received (i) if by mail on
the fourth calendar day after posting; (ii) by facsimile or personal delivery on
the date of actual transmission or personal delivery, as the case may be; and
(iii) if by overnight courier, on the next business day following the day such
notice is delivered to the courier service.

Section 7.02.     DISCLOSURE SCHEDULE.

         The Disclosure Schedule shall be arranged in separate parts
corresponding to the numbered and lettered sections contained in Articles III
and IV, as the case may be. The information disclosed in any numbered or
lettered part shall be deemed to be disclosed and incorporated in any other
numbered or lettered part where the relevance of such disclosure to another
numbered or lettered part would be reasonably apparent from such disclosure.

Section 7.03.     INTERPRETATION.

         The words "include," "includes" and "including" when used herein shall
be deemed in each case to be followed by the words "without limitation." The
table of contents and headings contained in this Agreement are for reference
purposes only and shall not affect in any way the meaning or interpretation of
this Agreement.


                                       53
<PAGE>   58

Section 7.04.     COUNTERPARTS.

         This Agreement may be executed in one or more counterparts, all of
which shall be considered one and the same agreement and shall become effective
when one or more counterparts have been signed by each of the parties and
delivered to the other party, it being understood that all parties need not sign
the same counterpart.

Section 7.05.     ENTIRE AGREEMENT; ASSIGNMENT.

         This Agreement, the Exhibits hereto, the Disclosure Schedule, and the
Related Agreements (including the Indemnity and Escrow Agreement, the
Transmittal Letter and the Investment Letter) (i) constitute the entire
agreement among the parties with respect to the subject matter hereof and
supersede all prior agreements and understandings both written and oral, among
the parties with respect to the subject matter hereof, (ii) except as set forth
in Section 8.05 below, are not intended to confer upon any other person any
rights or remedies hereunder; and (iii) shall not be assigned by operation of
law or otherwise.

Section 7.06.     THIRD PARTY BENEFICIARIES.

         It is the intention of the parties that the Stockholders be considered
third party beneficiaries of the terms and provisions contained in this
Agreement, including but not limited to the rights, obligations and agreements
contained in Article II herein. Further, such Stockholders shall have a vested
right to enforce the provisions of Article II hereof upon compliance with the
terms and provisions contained in this Agreement.

Section 7.07.     SEVERABILITY.

         In the event that any provision of this Agreement or the application
thereof becomes or is declared by a court of competent jurisdiction to be
illegal, void or unenforceable, the remainder of this Agreement will continue in
full force and effect and the application of such provision to other persons or
circumstances will be interpreted so as reasonably to effect the intent of the
parties hereto. The parties further agree to replace such void or unenforceable
provision of this Agreement with a valid and enforceable provision that will
achieve, to the extent possible, the economic, business and other purposes of
such void or unenforceable provision.

Section 7.08.     OTHER REMEDIES.

         Except as otherwise provided herein, any and all remedies herein
expressly conferred upon a party will be deemed cumulative with and not
exclusive of any other remedy conferred hereby, or by law or equity upon such
party, and the exercise by a party of any one remedy will not preclude the
exercise of any other remedy.


                                       54
<PAGE>   59

Section 7.09.     GOVERNING LAW.

         This Agreement shall be governed by and construed in accordance with
the laws of the State of Colorado, regardless of the laws that might otherwise
govern under applicable principles of conflicts of laws thereof. Each of the
parties hereto irrevocably consents to the exclusive jurisdiction and venue of
any court within the City and County of Denver, State of Colorado, in connection
with any matter based upon or arising out of this Agreement or the matters
contemplated herein, which matters are not subject to arbitration under Section
9.04, and agrees that process may be served upon them in any manner authorized
by the laws of the State of Colorado for such persons and waives and covenants
not to assert or plead any objection which they might otherwise have to such
jurisdiction, venue and such process.

Section 7.10.     ARBITRATION.

         All disputes and all other controversies or claims arising out of or
relating to this Agreement or any Related Agreements, or the breach thereof,
other than a claim for equitable relief, shall be settled by arbitration in
accordance with the Commercial Arbitration Rules of the American Arbitration
Association in Denver, Colorado. One arbitrator shall be selected by the
indemnifying party or parties, one arbitrator shall be selected by the
indemnified party, and the third arbitrator shall be chosen by the first two
arbitrators chosen. The cost and expense of arbitration shall be shared equally
by the parties to the arbitration, regardless of which party or parties prevail.
The arbitration shall be conducted in accordance with the following time
schedule unless otherwise mutually agreed to in writing by the parties: (i)
parties to the arbitration proceeding shall each appoint their respective
arbitrator within fifteen (15) business days after the end of the Notice Period;
(ii) within five (5) business days thereafter, such arbitrators shall appoint
the third arbitrator; (iii) promptly after appointment of the third arbitrator,
the arbitrators shall authorize the parties to conduct reasonable discovery,
including document productions and depositions, as specified by the arbitrators,
which discovery shall end no later than thirty days after the appointment of the
third arbitrator unless the arbitrators, with the consent of all parties, agree
to extend such period; (iv) the arbitrators shall schedule a hearing on the
dispute within 30 days after the date on which the discovery is scheduled to
end; and (v) within fifteen (15) business days after the date of the hearing
referenced in clause (iv) the arbitrators shall render their decision. The
decision or award of the arbitrators shall be final and binding upon the parties
hereto to the same extent and to the same degree as if the matter had been
adjudicated by a court of competent jurisdiction and shall be enforceable under
the Federal Arbitration Act.

Section 7.11.     AMENDMENT.

         This Agreement may be amended by the parties hereto at any time by
execution of an instrument in writing signed on behalf of each of the parties
hereto and the Stockholders' Representatives.


                                       55
<PAGE>   60

Section 7.12.     EXTENSION: WAIVER.

         Parent, on the one hand, and the Company, on the other hand, may, to
the extent legally allowed, (i) extend the time for the performance of any of
the obligations of the other party hereto, (ii) waive any inaccuracies in the
representations and warranties made to such party contained herein or in any
document delivered pursuant hereto, and (iii) waive compliance with any of the
agreements or conditions for the benefit of such party contained herein,
provided such waiver or extension shall not adversely effect the Stockholders.
Any agreement on the part of a party hereto to any such extension or waiver
shall be valid only if set forth in an instrument in writing signed on behalf of
such party.

Section 7.13.     RULES OF CONSTRUCTION.

         The parties hereto agree that they have been represented by counsel
during the negotiation and execution of this Agreement and, therefor, waive the
application of any law, regulation, holding or rule of construction providing
that ambiguities in an agreement or other document will be construed against the
party drafting such agreement or document.

Section 7.14.     KNOWLEDGE.

         Whenever the term to the "knowledge of the Company," or similar phrase,
is used in this Agreement, such phrase shall mean the actual knowledge of the
Company's directors and executive officers and knowledge that could have been
obtained by the Company's executive officers with respect to those matters that
would cause a reasonable person, in a similar position, to investigate the
matter further and that could have been obtained from such investigation without
undue effort.


                                       56
<PAGE>   61


         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed by their respective authorized officer or person as of the day and
year first above written.


                                 ATRIX LABORATORIES, INC.


                                 By:  /s/ JOHN E. URHEIM
                                      ------------------------------------------
                                      John E. Urheim, Vice Chairman and Chief
                                      Executive Officer


                                 ATRIX ACQUISITION CORPORATION


                                 By:  /s/ JOHN E. URHEIM
                                      ------------------------------------------
                                      John E. Urheim, President



                                 VIROTEX CORPORATION


                                 By:  /s/ JEFFREY M. SOINSKI
                                      ------------------------------------------
                                      Jeffrey M. Soinski, President and
                                      Chief Executive Officer



                                       57


<PAGE>   1
                                                                    EXHIBIT 10.2



                              CERTIFICATE OF MERGER

                                       OF

                          ATRIX ACQUISITION CORPORATION

                                      INTO

                               VIROTEX CORPORATION


     The undersigned corporation organized and existing under and by virtue of
the General Corporation Law of the State of Delaware (the "DGCL"),

     DOES HEREBY CERTIFY:

     FIRST: That the name and state of incorporation of each of the constituent
corporations of the merger are as follows:

         Name                                 State of Incorporation
         ----                                 ----------------------

         Atrix Acquisition Corporation        Delaware

         ViroTex Corporation                  Delaware

     SECOND: That an Agreement and Plan of Reorganization between Atrix
Laboratories, Inc., a Delaware corporation, Atrix Acquisition Corporation,
ViroTex Corporation and certain shareholders of ViroTex Corporation as named
therein (collectively, the "Parties") has been approved, adopted, certified,
executed and acknowledged by Atrix Acquisition Corporation and ViroTex
Corporation in accordance with the requirements of Section 251 of the DGCL.

     THIRD: That the name of the surviving corporation of the merger is ViroTex
Corporation.

     FOURTH: That the Certificate of Incorporation of ViroTex Corporation shall
be amended and restated in the form attached hereto as Exhibit A.

     FIFTH: That the executed Agreement and Plan of Reorganization is on file at
the principal place of business of the surviving corporation, a copy of which
will be furnished, on request and without charge, to any Stockholder of any
constituent corporation. The address of the principal place of business of the
surviving corporation is 2579 Midpoint Drive, Fort Collins, Colorado 80525.


<PAGE>   2



     IN WITNESS WHEREOF, the undersigned has caused this agreement to be duly
executed by its authorized officer as of this 24th day of November, 1998.


                              VIROTEX CORPORATION



                              By  /s/ JEFFREY M. SOINSKI
                                  ---------------------------------------------
                                  Jeffrey M. Soinski, President and Chief
                                  Executive Officer







                                       2
<PAGE>   3



                                    EXHIBIT A

                              AMENDED AND RESTATED
                          CERTIFICATE OF INCORPORATION

                                       OF

                               VIROTEX CORPORATION


   IT IS HEREBY CERTIFIED THAT,

     A. The present name of the corporation (hereinafter called the
"Corporation") is ViroTex Corporation. The name under which the Corporation was
originally incorporated is Viro-Tex Corporation, and the date of filing the
original certificate of incorporation of the Corporation with the Delaware
Secretary of State is May 4, 1988.

     B. The certificate of incorporation of the Corporation, as amended, is
hereby amended in its entirety by deleting all of the original Articles and
substituting in lieu thereof the new Articles set forth in the Amended and
Restated Certificate of Incorporation hereinafter provided for.

     C. The provisions of the certificate of incorporation of the Corporation as
heretofore amended, and as herein amended, are hereby restated and integrated
into the single instrument which is hereinafter set forth, and which is entitled
Amended and Restated Certificate of Incorporation of ViroTex Corporation,
without any further amendments other than the amendments herein certified.

     D. The amendments and the restatement of the certificate of incorporation
herein certified have been duly adopted by the stockholders in accordance with
the provisions of Sections 228, 242 and 245 of the General Corporation Law of
the State of Delaware.

     E. The certificate of incorporation of the Corporation, as amended and
restated herein, shall at the effective time of this amended and restated
certificate of incorporation, read as follows:



                                       3
<PAGE>   4



                              AMENDED AND RESTATED
                          CERTIFICATE OF INCORPORATION

                                       OF

                               VIROTEX CORPORATION

     1. The name of the Corporation is ViroTex Corporation.

     2. The address of its registered office in the State of Delaware is 1013
Centre Road, Wilmington, 19805, County of New Castle. The name of its registered
agent at such address is Corporation Service Company.

     3. The nature of the business of the Corporation and the objects or
purposes to be transacted, promoted or carried on by it are as follows: To
engage in any lawful act or activity for which corporations may be organized
under the General Corporation Law of the State of Delaware.

     4. The total number of shares of all classes of stock that the Corporation
is authorized to issue is One Thousand (1,000) shares of Common Stock with a par
value of $.001 per share.

     5. The board of directors is expressly authorized to make, alter, or repeal
the bylaws of the Corporation.

     6. Elections of directors need not be by written ballot unless the bylaws
of the Corporation shall so provide.

     7. Whenever a compromise or arrangement is proposed between this
Corporation and its creditors or any class of them and/or between this
Corporation and its stockholders or any class of them, any court of equitable
jurisdiction within the State of Delaware may, on the application in a summary
way of this Corporation or of any creditor or stockholder thereof, or on the
application of any receiver or receivers appointed for this Corporation under
the provisions of Section 291 of Title 8 of the Delaware Code or on the
application of trustees in dissolution or of any receiver or receivers appointed
for this Corporation under the provisions of Section 279 of Title 8 of the
Delaware Code order a meeting of the creditors or class of creditors, and/or of
the stockholders or class of stockholders of this Corporation, as the case may
be, to be summoned in such manner as the said court directs. If a majority in
number representing three-fourths in value of the creditors or class of
creditors, and/or of the stockholders or class of stockholders of this
Corporation, as the case may be, agree to any compromise or arrangement and to
any reorganization of this Corporation as a consequence of such compromise or
arrangement, the said compromise or arrangement and the said reorganization
shall, if sanctioned by the court to which the said application has been made,
be binding on all the creditors or class of creditors, and/or on all the
stockholders or class of stockholders, of this Corporation, as the case may be,
and also on this Corporation.



                                       4
<PAGE>   5

     8. The Corporation reserves the right to amend, alter, change or repeal any
provision contained in this Certificate of Incorporation, in the manner now or
hereafter prescribed by statute, and all rights conferred upon stockholders
herein are granted subject to this reservation.

     9. To the fullest extent permitted by Delaware statutory or decisional law,
as amended or interpreted, no director of this Corporation shall be personally
liable to the Corporation or its stockholders for monetary damages for breach of
fiduciary duty as a director. This Article 9 does not affect the availability of
equitable remedies for breach of fiduciary duties.

     IN WITNESS WHEREOF, the undersigned has caused this document to be duly
executed by its authorized officer as of this 24th day of November, 1998.

                              VIROTEX CORPORATION



                              By  /s/ JEFFREY M. SOINSKI
                                  ---------------------------------------------
                                  Jeffrey M. Soinski, President and Chief
                                  Executive Officer



                                       5

<PAGE>   1
                                  EXHIBIT 99.1

          ATRIX LABORATORIES ACQUIRES VIROTEX; GAINS FOUR SHORT-ACTING
                           DRUG DELIVERY TECHNOLOGIES

         FORT COLLINS, Colo. (November 30, 1998) * Atrix Laboratories, Inc.
(NASDAQ NM: ATRX) today announced that it has acquired ViroTex Corporation, a
privately owned drug delivery company. The acquisition expands the company's
drug delivery technology base and is expected to accelerate and diversify future
revenue growth.

         "The addition of ViroTex will allow us to build on the success of our
core ATRIGEL(R) drug delivery platform with important complementary technologies
that we expect will significantly enhance shareholder value," said John Urheim,
vice chairman and chief executive officer of Atrix. "The acquisition includes a
current revenue stream of royalties from Viractin(R) (tetracaine 2%), an
over-the-counter (OTC) product for cold sores and fever blisters marketed by
J.B. Williams Company, and a product pipeline of four near-term OTC products for
oral care and skin care, as well as two prescription products ready to enter
Phase I clinical trials for oral care and severe acne."

         Under the terms of the acquisition agreement, which has been approved
by each company's board of directors, Atrix has acquired ViroTex for $7.5
million in cash and $500,000 in Atrix common stock. Also, ViroTex shareholders
may earn up to an additional $3 million in Atrix common stock based on the
success of ViroTex's products and technologies in the marketplace.

         Atrix expects this acquisition to contribute approximately $2 to $3
million to the company's 1999 revenues and to favorably impact 1999 earnings.
The transaction will be accounted for as a purchase, and approximately $3.5
million of the purchase price is expected to be charged to in-process research
and development and will be reflected in Atrix Laboratories' financial results
for the fourth quarter ended December 31, 1998.

         Founded in 1988 and headquartered in The Woodlands, Texas, ViroTex
develops OTC and prescription products based on proprietary drug delivery
systems that provide topical and transmucosal delivery of medications requiring
fast onset of action. The ViroTex immediate-release systems complement Atrix's
ATRIGEL(R) drug delivery technology, which releases drugs for extended periods
of time ranging from days to months. Both ATRIGEL and the ViroTex systems can be
engineered for either local or systemic delivery of a variety of small
molecules, peptides, proteins and vaccines.

         "Adding the ViroTex technologies significantly strengthens our research
and development base, and creates both immediate and longer-term opportunities
to provide enabling biodegradable drug delivery systems for a variety of
medical, dental and veterinary applications," said Dr. Richard L. Jackson,
Atrix's senior vice president of research and development. "In addition to
existing ViroTex products, we are acquiring four polymer- and solvent-based drug
delivery technologies that will allow Atrix to offer pharmaceutical and
biotechnology companies an array of immediate and sustained-release
biodegradable drug delivery systems to meet their product development needs."



<PAGE>   2

         Jeffrey Soinski, president and chief executive officer of ViroTex,
commented: "Although ViroTex has been successful in developing OTC products such
as Viractin on our own, we realize that the great potential represented by our
technologies can best be achieved by combining with another drug delivery
company. We are very excited about joining forces with Atrix and working
together to get our products into the marketplace."

         "The acquisition of ViroTex is an excellent first step in expanding our
drug delivery business beyond the ATRIGEL technology," Urheim said. "Because
development times for OTC products oftentimes are far shorter than for
prescription products, we believe that the ViroTex acquisition can contribute to
the company's near-term growth. When combined with sales of our ATRIDOX product,
this will help us expand revenues more quickly as we complete, and in some cases
accelerate, the development of long-term prescription drug projects. In
addition, several of these products can be manufactured in our state-of-the-art
facility for company-wide operating efficiencies."

         In September 1998 Atrix received U.S. Food and Drug Administration
approval for ATRIDOX(R) (doxycycline hyclate 10.0% in the ATRIGEL delivery
system), a new prescription antibiotic therapy that kills the bacteria
associated with periodontal disease. The ATRIGEL technology is now being used to
develop additional products for dentistry, oncology and orthopedics.

         The ViroTex drug delivery technologies include Bioerodible Mucoadhesive
(BEMA*) film, which adheres to the mucosal tissue of the mouth or vagina and
allows the rapid or controlled delivery of medication through the tissue as the
film dissolves away; the Mucocutaneous Adsorption (MCA) system, a moisture
resistant, film-forming gel or aerosol that binds drugs to skin or mucosal
tissue for more efficient drug delivery; the Biocompatible Polymer (BCP) system,
which delivers drug to a wound and dries to a protective film to create a moist
environment for healing; and the Solvent/Microparticulate (SMP) system, which
combines dissolved drug compounds with a microparticulate suspension of the drug
in a single formulation, allowing the medication to be delivered in two stages
to improve the absorption of relatively insoluble active compounds.

         Atrix Laboratories, Inc. develops, manufactures and markets dental,
medical and veterinary products based on its proprietary ATRIGEL(R)
biodegradable polymeric technology, which can be used for a broad range of drug
delivery and biomaterial applications. Additional information is available on
the Atrix Laboratories, Inc. Web site at http://www.atrixlabs.com.

         Forward-looking statements in this release involve a number of risks
and uncertainties including, but not limited to regulatory reviews, product
demand, pricing, market acceptance, changing economic conditions, risks in
product and technology development, the effect of the company's accounting
policies and other risk factors detailed in the company's SEC filings.

                                      # # #

                                       2


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