BIOJECT MEDICAL TECHNOLOGIES INC
8-K, 1997-10-31
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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                       SECURITIES AND EXCHANGE COMMISSION

                            WASHINGTON, D.C.  20549


                                ---------------


                                    FORM 8-K

                                 CURRENT REPORT




                     Pursuant to Section 13 or 15(d) of the
                        Securities Exchange Act of 1934



Date of Report (Date of earliest event reported) October 15, 1997
                                                 -----------------

                       BIOJECT MEDICAL TECHNOLOGIES INC.
               --------------------------------------------------
               (Exact Name of Registrant as Specified in Charter)


                                     Oregon
                 ----------------------------------------------
                 (State or Other Jurisdiction of Incorporation)



          0-15360                              93-1099680
   ------------------------         ------------------------------
  (Commission File Number)         (IRS Employer Identification No.)


      7620 SW Bridgeport Road 
         Portland, Oregon                          97224               
- ---------------------------------------          ---------
(Address of Principal Executive Offices)         (Zip Code)


Registrant's telephone number, including area code  (503) 639-7221
                                                    --------------


                                     N/A
         -------------------------------------------------------------
         (Former Name or Former Address, if Changed Since Last Report)



Item 7.  Exhibits

10.41   Securities Purchase Agreement between Elan 
        International Services, Ltd. and Bioject Medical Technologies 
        Inc. dated October 15, 1997. 

10.42   Bioject Medical Technologies Inc. Registration Rights 
        Agreement between Elan International Services, Ltd. and 
        Bioject Medical Technologies Inc. dated October 15, 1997.  

10.43   Series K Warrant to Purchase Shares of Common Stock 
        dated October 15, 1997.  



                               SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf 
by the undersigned hereunto duly authorized.



                                  BIOJECT MEDICAL TECHNOLOGIES INC.
                                          
                                          
                                          
Date:    October 31, 1997          By /s/ Peggy J. Miller
                                   ----------------------------------
                                    Peggy J. Miller
                                    Vice President, Chief Financial
                                    Officer, Secretary/Treasurer
                                          
EXHIBIT INDEX

The following exhibits are attached to this form 8-K 

10.41   Securities Purchase Agreement between Elan International
        Services, Ltd. and Bioject Medical Technologies Inc.
        dated October 15, 1997.

10.42  Bioject Medical Technologies Inc. Registration Rights 
       Agreement between Elan International Services, Ltd. and
       Bioject Medical Technologies Inc. dated October 15, 1997.

10.43  Series K Warrant to Purchase Shares of Common Stock
       dated October 15, 1997.


                                                             EXHIBIT 10.41
                                                                          
                     SECURITIES PURCHASE AGREEMENT

SECURITIES PURCHASE AGREEMENT dated as of October 15, 1997, between Bioject 
Medical Technologies Inc., an Oregon corporation (the "Company"), and Elan 
International Services, Ltd., a Bermuda corporation ("EIS).


R E C I T A L S:

A.  The Company desires to issue and sell to EIS and EIS desires to purchase 
from the Company, on the Closing Date (as defined below), as provided herein, 
a promissory  note in the original principal amount of $12,015,000, in the 
form attached hereto as Exhibit A (the "Promissory Note"), for aggregate 
consideration of $12,015,000 to be paid in cash by EIS to the Company on the 
Closing Date.

B.  The Company desires to issue and sell to EIS, and EIS desires to purchase 
from the Company, (i) 2,727,273 shares of the Company's common stock, without 
par value (the "Common Stock"), and (ii) a warrant to acquire 1,750,000 shares 
(subject to adjustment) of Common Stock, in the form attached hereto as 
Exhibit B (the "Warrant"), for aggregate consideration of $3,000,000  to be 
paid in cash by EIS to the Company on the Closing Date.

C.  In the event that Stockholder Approval (as defined herein) is obtained, 
the Promissory Note shall be exchanged by EIS for certain shares of Series A 
Convertible Preferred Stock (the "Series A Preferred Stock") and Series B 
Convertible Preferred Stock (the "Series B Preferred Stock"; together with the 
Series A Preferred Stock and the Series C Preferred Stock (as defined below), 
the "Preferred Stock"; together with the Common Stock and the Warrant, the 
"Securities"), as provided herein, which shall be issued to EIS pursuant to 
the Certificate of Designations in the form attached hereto as Exhibit C (the 
"Certificate of Designations").

D.  In the event that the Stockholder Approval is obtained, EIS has agreed 
that for a period of 30 months thereafter EIS may, at the Company's option 
(but subject to the conditions contained herein), be required to fund up to  
$4,000,000 to the Company to purchase  additional shares of preferred stock 
(the "Series C Preferred Stock").

E.  The Company has previously caused to be formed Bioject JV Subsidiary Inc., 
an Oregon corporation ("Newco"), for the purpose of developing and 
commercializing certain technologies relating to glucose monitoring.  The 
initial stockholders in Newco shall be the Company and EIS.  The parties 
intend, as provided herein, that the proceeds of the issuance of Promissory 
Note shall be applied by the Company solely to fund the Company's initial  
investment in Newco, as provided herein.

F.  The Company and EIS are executing and delivering on the date hereof a 
Registration Rights Agreement in the form attached hereto as Exhibit D (the 
"Registration Rights Agreement"; together with this Agreement, the Securities, 
and each other document or instrument executed and delivered in connection 
with the transactions contemplated hereby, the "Transaction Documents") in 
respect of the initial purchase of Common Stock and the Common Stock 
underlying the Securities and any other Common Stock that may at any time be 
acquired or owned by EIS or its affiliates.


A G R E E M E N T:

The parties agree as follows:

SECTION 1.  Closings.  (a)  Time and Place.  The closing of the transactions 
contemplated hereby (the "Closing") shall occur on the date hereof (the 
"Closing Date"), at the offices of counsel to EIS or such other place as the 
parties may agree.

(b)  Issuance of Securities.  At the Closing, (x) the Company shall issue and 
sell to EIS, and EIS shall purchase from the Company the Promissory Note, upon 
the terms and subject to the conditions set forth herein, for an aggregate 
purchase price of $12,015,000, and (y) the Company shall issue and sell to 
EIS, and EIS shall purchase from the Company (i) 2,727,273 shares of Common 
Stock (the "Initial Common Stock") and the Warrant, for an aggregate purchase 
price of $3,000,000  (the "Closing Consideration").  Of such Closing 
Consideration, $.001 per share of Common Stock issueable upon exercise of the 
Warrant shall be deemed allocated toward the purchase price of the Warrant.

(c)    Delivery.  At the Closing, EIS shall pay the purchase price for the  
Promissory Note, Initial Common Stock and the Warrant in cash by wire transfer 
to an account or accounts designated by the Company and the parties hereto 
shall execute and deliver to each other, as applicable:  (i) the Promissory 
Note; (ii) a certificate or certificates for the shares of the Initial Common 
Stock; (iii) the Warrant; and (iv) certificates as to the incumbency of the 
officers executing this Agreement and each of the other documents or 
instruments executed in connection herewith.   In addition, at the Closing, 
the Company shall cause to be delivered to EIS an opinion of counsel in form 
attached hereto as Exhibit E.

(d)   Additional Closings. (i) In the event that Stockholder Approval shall 
have been obtained on or prior to February 1, 1998, for a period of 30 months 
after the date thereof, upon at least 30 days notice, the Company shall be 
entitled from time to time, subject to the conditions herein, to require EIS 
to purchase all or part of the Series C Preferred Stock.  The Series C 
Preferred Stock shall be redeemable and convertible in the same manner and 
subject to the same other conditions as the Series B Preferred Stock; provided 
that the issuance and conversion prices of each share of  Series C Preferred 
Stock shall be equal to ten times the average of the last traded price for the 
shares of Common Stock as reported by the Nasdaq Stock Market for 10 
consecutive trading days ending on the day that is two business days prior to 
the date of such issuance .  In the event that Stockholder Approval has not 
been obtained on or prior to February 1, 1998, EIS, in its sole discretion, 
shall be entitled to deem such lack of approval as a rejection of the Proposal 
(as defined in Section 4(f)) by the Company's stockholders.

(ii)  It shall be a condition to EIS's obligation to purchase any Series C 
Preferred Stock that (A) each of the representations and warranties set forth 
in Section 2(a), (b)(iii), (c), (d) and (l) shall be true and correct in all 
material respects as if the date hereof were the proposed funding date 
thereof; provided, that any reference to the Quarterly Report shall refer to 
the most recent quarterly report on Form 10-Q and/or any report filed pursuant 
to Section 13 of the Securities Exchange Act of 1934 (the "Exchange Act"), 
required to be filed by the Company under applicable law immediately prior to 
such funding date and SEC Filings shall refer to all filings required to be 
made by the Company under applicable law on or prior to such date, (B) there 
shall be no default or breach in any material respect by the Company of a 
material obligation under any of the Transaction Documents  or any other 
agreement between the Company or any of its affiliates, on the one hand, and 
EIS or any of their affiliates, on the other hand, and (C) the Company shall 
have executed and delivered to EIS each document or instrument  that shall be 
customary and appropriate for such transaction, including duly executed and 
delivered counterparts of certificates for the Series C Preferred Stock.

(e)   Exemption from Registration.  The Securities will be issued under an 
exemption or exemptions from registration under the Securities Act of 1933, as 
amended; accordingly, the certificates evidencing the Securities shall, upon 
issuance, contain the following legend:

THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE 
SECURITIES ACT OF 1933 AND MAY NOT UNDER ANY CIRCUMSTANCES BE  TRANSFERRED 
WITHOUT AN EFFECTIVE REGISTRATION STATEMENT FOR SUCH SECURITIES UNDER THE 
SECURITIES ACT OF 1933 AND ANY APPLICABLE STATE SECURITIES LAWS OR AN OPINION 
OF COUNSEL SATISFACTORY TO THE CORPORATION THAT REGISTRATION IS NOT REQUIRED 
UNDER SUCH ACT OR APPLICABLE STATE SECURITIES LAWS.

(f)   Registration Rights Agreement.  On the date hereof, the Company, and EIS 
are each executing and delivering the Registration Rights Agreement, covering 
the shares of Common Stock issuable hereunder or upon conversion, exercise or 
exchange of any of the Securities or any other shares of Common Stock 
hereafter acquired by EIS or its affiliates from the Company.

SECTION 2.  Representations and Warranties of the Company.  (a)  Organization.  
The Company is duly organized, validly existing and in good standing under the 
laws of the State of Oregon and has all requisite corporate power and 
authority to own and lease its properties, to carry on its business as 
presently conducted and as proposed to be conducted and to consummate the 
transactions contemplated hereby.  The Company is qualified and in good 
standing to do business in jurisdictions set forth on Schedule 2(a), which 
constitute all of the jurisdictions in which the nature of the business 
conducted or the property owned by it requires such qualification, except 
where the failure to so qualify would not have a material adverse effect on 
the business, prospects, properties or condition (financial or otherwise) of 
the Company (a "Material Adverse Effect").

(b)  Capitalization.  (i) The authorized and number of outstanding shares of 
capital stock of the Company as of September 30, 1997 is 22,475,688.

(ii)  Except as set forth in Schedule 2(b) and in the Company's quarterly 
report on Form 10-Q filed with the Securities and exchange Commission on 
August 14, 1997 (the "Quarterly Report"), as of the Closing there are no 
options, warrants or other rights outstanding to purchase or otherwise 
acquire, or any securities convertible into, any of the Company's authorized 
capital stock.  Other than as set forth in this Agreement and as described in 
Schedule 2(b), there are no agreements, arrangements or understandings 
concerning the voting, acquisition or disposition of any of the Company's 
outstanding securities to which the Company is a party or of which it is 
otherwise aware, and, other than as set forth in Schedule 2(b) or in the 
Registration Rights Agreement, there are no agreements to register any of the 
Company's outstanding securities under the U.S. federal securities acts.

(iii)  All of the outstanding shares of capital stock of the Company have been 
issued in accordance with applicable state and federal laws and regulations 
governing the sale and purchase of securities, all of such shares of have duly 
and validly issued and are fully paid and non-assessable, and none of such 
shares carries preemptive or similar rights.  

 (c)  Authorization of Transaction Documents.  The Company has full corporate 
power and authority to execute and deliver this Agreement and each of the 
other Transaction Documents, and to perform its obligations hereunder and 
thereunder.  Except for Stockholder Approval the execution, delivery and 
performance by the Company of the Transaction Documents (including the 
issuance and sale of the Securities) have been authorized by all requisite 
corporate actions by the Company; and the Transaction Documents (including the 
issuance and sale of the Securities) have been duly executed and delivered by 
the Company are the valid and binding obligations of the Company, enforceable 
against each in accordance with their respective terms.

(d)  No Violation.  The execution, delivery and performance by the Company of 
the Transaction Documents (including the issuance and sale of the Securities), 
and compliance with the provisions thereof by the Company, will not (i) 
violate any provision of applicable law, statute, rule or regulation 
applicable to the Company or any ruling, writ, injunction, order, judgment or 
decree of any court, arbitrator, administrative agency or other governmental 
body applicable to the Company or any of their respective properties or assets 
or (ii) conflict with or result in a breach of any of the terms, conditions or 
provisions of, or constitute (with notice or lapse of time or both) a default 
(or give rise to any right of termination, cancellation or acceleration) 
under, or result in the creation of, any Encumbrance (as defined below) upon 
any of the properties or assets of the Company under its Articles of 
Incorporation, as amended, its Certificate of Designations (in the form to be 
filed as provided herein) or By-laws, or any material contract to which the 
Company is a party, except where such violation, conflict or breach would not, 
individually or in the aggregate, have a Material Adverse Effect on the 
Company (as used in connection to either of them, a "Material Adverse 
Effect").  As used herein, "Encumbrance" shall mean any liens, charges, 
encumbrances, equities, claims, options, proxies, pledges, security interests, 
or other similar rights of any nature, except for such conflicts, breaches or 
defaults which would not, individually or in the aggregate, have a Material 
Adverse Effect.

(e)  Approvals.  Except as set forth on Schedule 2(e), no material permit, 
authorization, consent or approval of or by, or any notification of or filing 
with, any person or entity (governmental or otherwise) is required in 
connection with the execution, delivery or performance of the Transaction 
Documents (including the issuance and sale of the Securities) by the Company 
or Newco. Except for the Stockholder Approval, there is no approval of the 
Company's stockholders required under applicable laws in connection with the 
execution and delivery the Transaction Documents or the consummation of the 
transactions contemplated thereby, including the filing of the Certificate of 
Designations and the issuance of the Securities.

(f)  Filings, Taxes and Financial Statements.  (i)  The Company has filed its 
annual report on Form 10-K for the year ended March 31, 1997, its related 
proxy materials and its quarterly reports on Form 10-Q for the quarter ended 
June 30, 1997 and the Quarterly Report (collectively, including all exhibits 
and schedules required to be filed in connection therewith, the "SEC Filings") 
with the Securities and Exchange Commission, the Nasdaq Stock Market and any 
other required person or entity (governmental or otherwise) in a timely manner 
and as otherwise required by applicable laws and regulations, including the 
federal securities acts. The audited financial statements of the Company for 
the fiscal year ended March 31, 1997 included in the SEC Filings (the "Audited 
Financial Statements"), and the Company's unaudited balance sheet for the 
period ending June 30, 1997, together with the accompanying statements of 
operations and cash flows including the notes thereto (the "June Financial 
Statements"; collectively, with the Audited Financial Statements, the 
"Financial Statements") are accurate and complete in all material respects and 
fairly present the financial condition of the Company as at the dates thereof 
and have been prepared in accordance with generally accepted accounting 
principles applied on a consistent basis throughout the periods indicated 
(except as may be otherwise indicated in such financial statements or the 
notes thereto), subject, in the case of the June Financial Statements, to 
normal year-end audit adjustments (which shall not be material in the 
aggregate) and the absence of footnote disclosures.

(ii) The Company has filed in a timely manner all material federal, state, 
local and foreign tax returns, reports and filings (collectively, "Returns"), 
including income, franchise, property and other taxes, and has paid or accrued 
the appropriate amounts reflected on such Returns.  None of the Returns have 
been audited or challenged, nor has the Company received any notice of 
challenge nor have any of the amounts or other data included in the Returns 
been challenged or reviewed by any governmental authority.

(iii) Except as listed in Schedule 2(f), which sets forth a true and accurate 
list and description of any such plans maintained or sponsored by the Company 
or to which the Company is required to make contributions, the Company does 
not maintain, sponsor, is not required to make contributions to or otherwise 
have any liability with respect to any pension, profit sharing, thrift or 
other retirement plan, employee stock ownership plan, deferred compensation, 
stock ownership, stock purchase, performance share, bonus or other incentive 
plan, severance plan, health or group insurance plan, welfare plan, or other 
similar plan, agreement, policy or understanding (whether written or oral), 
whether or not such plan is intended to be qualified under Section 401(a) of 
the Code, within the meaning of Section 3(3) of the Employee Retirement Income 
Security Act of 1974, as amended, which plan covers any employee or former 
employee of the Company.

(g)  Absence of Changes.  Except as set forth on Schedule 2(g), since June 30, 
1997, there has not been (a) any material adverse change in the business, 
properties, condition (financial or otherwise), operations or prospects of the 
Company; (b) any damage, destruction or loss, whether or not covered by 
insurance, materially and adversely affecting the business, properties, 
condition (financial or otherwise), operations or prospects of the Company; 
(c) any declaration, setting aside or payment of any dividend or other 
distribution or payment (whether in cash, stock or property) in respect of the 
capital stock of the Company, or any redemption or other acquisition of such 
stock by the Company; (d) any disposal or lapse of any trade secret, 
invention, patent, trademark, trademark registration, service mark, service 
mark registration, copyright, copyright registration, or any application 
therefor or filing in respect thereof; (e) loss of the services of any of the 
key officers or key employees of the Company; (f) any incurrence of or entry 
into any liability, mortgage, lien, commitment or transaction, including 
without limitation, any borrowing (or assumption or guarantee thereof) or 
guarantee of a third party's obligations, or capital expenditure (or lease in 
the nature of a conditional purchase of capital equipment) in excess of 
$50,000; or (g) any material change by the Company in accounting methods or 
principles or (h) any change in the assets, liabilities, condition (financial 
or otherwise), results or operations or prospects of the Company from those 
reflected on the Quarterly Report, except changes in the ordinary course of 
business that have not, individually or in the aggregate, had a Material 
Adverse Effect.

(h)  No Liabilities.  Except as set forth in the Quarterly Report or Schedule 
2(h) attached hereto, neither the Company nor Newco nor any of their 
respective subsidiaries has incurred or suffered any liability or obligation, 
matured or unmatured, contingent or otherwise, except in the ordinary course 
of business that have not, individually or in the aggregate, had a Material 
Adverse Effect.

(i)  Properties and Assets; Etc.  (i)  The Company owns all of its properties 
and assets, including patents, patent applications, continuations, 
continuations-in-part, extensions, trademarks and trademark applications, 
know-how and other intellectual property, as reflected in the Financial 
Statements, subject in each case, to no Encumbrances required to be disclosed 
in the Financial Statements except as set forth therein. Except as set forth 
on Schedule 2(i), (i) all of the Company's patents, trademarks, service marks, 
trade names, and copyrights are owned by the Company free and clear of all 
liens, claims and encumbrances and are valid and duly issued or existing; none 
of the Company's rights in or use of such patents, trademarks, service marks, 
trade names or copyrights has been or is currently being threatened to be, 
challenged; to the best of the Company's knowledge, without making any inquiry 
other than those, if any, routinely conducted by the Company in the ordinary 
course of business, no  current or currently planned product based upon the 
Company's intellectual property would infringe any patent, trademark, service 
mark, trade name or copyright of any other person or entity issued or pending 
on the Closing Date if the Company were to distribute, sell or manufacture 
such products; and the Company is not aware, after due inquiry, of any actual 
or threatened claim by any person or entity alleging any infringement by the 
Company of a patent, trademark, service mark, trade name or copyright 
possessed by such Person; (ii) all of such patents, trademark registrations, 
service mark registrations, trade name registrations and copyrights and 
copyright registrations, whether foreign or domestic, have been duly issued 
and have not been canceled, abandoned, or otherwise terminated; and (iii) all 
of the Company's patent applications, trademark applications, service mark 
applications, trade name applications and copyright applications have been 
duly filed.

(ii) Each of the Contracts listed as an exhibit to the Company's Annual Report 
on Form 10-K for the year ended March 31, 1997 is a legal and valid agreement 
binding upon each of the parties thereto and is in full force and effect and, 
to the best knowledge of the Company, there is no breach or default by any 
party thereunder.  Such Contracts constitute all material agreements, 
arrangements or understandings required to be included in such annual Report 
under Securities and Exchange Commission regulations promulgated in connection 
therewith.

(iii)  The Company has and maintains adequate and sufficient insurance, 
including liability, casualty and products liability insurance, covering risks 
associated with its business, properties and assets, including insurance that 
is customary for companies similarly situated.

(iv)   To the best of its knowledge, the Company, its business and properties 
and assets are in compliance, in all material respects, with all applicable 
laws and regulations, including without limitation, those relating to (a) 
health, safety and employee relations, (ii) environmental matters, including 
the discharge of any hazardous or potentially hazardous materials into the 
environment, and (iii) the development, commercialization and sale of 
pharmaceutical and biotechnology products, including all applicable 
regulations of the U.S. Food and Drug Administration and comparable foreign 
regulatory authorities.

(j)   Legal Proceedings, etc. There is no legal, administrative, arbitration 
or other action or proceeding or governmental investigation pending or , to 
the best of the Company's knowledge threatened against the Company, or any 
director, officer or employee of the Company, which is required to be 
described in the Company's Quarterly Report on Form 10-Q and is not so 
described.  The Company is not in violation of or default under, any material 
laws,  judgments, injunctions, orders or decrees of any court, governmental 
department, commission, agency, instrumentality or arbitrator applicable to 
its business. 

(k)  Disclosure.  The Company's Annual Report on Form 10-K for the year ended 
March 31, 1997 and periodic reports subsequently filed under Section 13 of the 
Exchange Act, and the representations and warranties set forth herein and the  
Transaction Documents, when viewed collectively, do not contain any untrue 
statement of a material fact or omit to state any material fact necessary to 
make the statements contained herein and therein not misleading.	

(l) Brokers or Finders.  Other than as set forth on Schedule 2(l), the Company 
has not retained any investment banker, broker or finder in connection with 
the transactions contemplated by the Transaction Documents; and the Company 
agrees to indemnify and hold EIS harmless against any liability, settlement or 
expense arising out of, or in connection with, any claim related thereto.

SECTION 3.  Representation and Warranties of EIS.  EIS hereby represents and 
warrants to the Company as follows:

(a)  Organization.  EIS is a corporation duly organized, validly existing and 
in good standing under the laws of Bermuda and has all requisite corporate 
power and authority to own and lease its properties, to carry on its business 
as presently conducted and as proposed to be conducted and to consummate the 
transactions contemplated hereby.  EIS  is qualified and in good standing to 
do business in each jurisdiction in which the nature of the business conducted 
or the property owned by it requires such qualification, except where the 
failure to so qualify would not reasonably be expected to have a material 
adverse effect on the business or condition (financial or otherwise) of EIS.

(b)  Authorization of Agreement.  EIS has full legal right, power and 
authority to enter into this Agreement and purchase and accept the Note, and 
perform its obligations hereunder, which have been duly authorized by all 
requisite corporate action.  This Agreement and the  purchase of the Note are 
the valid and binding obligations of EIS, enforceable against them in 
accordance with their terms.

(c)  No Conflicts.  The execution, delivery and performance by EIS of this 
Agreement, the purchase and acceptance of the Note and compliance with 
provisions hereof by EIS, will not (i) violate any provisions of applicable 
law, statute, rule or regulation applicable to EIS or any ruling, written, 
injunction, order, judgment or decree of any court, arbitration, 
administrative agency of other governmental body applicable to EIS of any of 
its properties or assets or (ii) conflict with or result in any breach of any 
of the terms, conditions or provisions of, or constitute (with notice or lapse 
of time to both) a default (or give rise to any right of termination, 
cancellation or acceleration) under, or result in the creation of any 
Encumbrance upon any of the properties or assets of EIS under the Certificate 
of Incorporation or By-laws of EIS or any material contract to which EIS is 
party, except where such violation conflict or breach would not, individually 
or in the aggregate, have a material adverse effect on EIS.

(d)  Approvals.  No permit, authorization, consents or approval of or by, or 
any notification of or filing with, any person or entity (governmental or 
otherwise) is required in connection with the execution, delivery or 
performance of this Agreement or the Note (including the funding and 
acceptance thereof) by EIS.

(e)  Investment Representations.  (i)  EIS is sophisticated in transactions of 
this type and capable of evaluating the merits and risks of the transactions 
described herein and in the other Transaction Documents, and have the capacity 
to protect their own interests.  EIS has not been formed solely for the 
purpose of entering into the transactions described herein and therein and is 
acquiring the Securities for investment for its own account, not as a nominee 
or agent, and not with the view to, or for sale in connection with, any 
distribution of any part thereof; provided, that EIS shall be permitted to 
convert or exchange such Securities and/or transfer them as permitted herein 
and under applicable law.  EIS has been afforded the opportunity to ask 
questions of and information about the Company and its business and prospects, 
from management and representatives of the Company, and have relied on its own 
independent judgment in making a judgment about an investment in the 
Securities. 

(ii)  Nothing contained in this Section 3(e) shall limit any of the Company's 
representations or warranties or limit EIS's recourse in respect thereof.

(iii) Other than as set forth on Schedule 3(e)(iii), EIS have not retained any 
investment banker, broker or finder in connection with the transactions 
contemplated by the Transaction Documents; and EIS agree to indemnify and hold 
the Company harmless against any liability, settlement or expense arising out 
of, or in connection with, any claim related thereto.

SECTION 4.  Covenants of the Company.  (a) Non-disclosure.  From and after the 
date hereof, the Company shall not disclose to any person or entity (other 
than its directors, officers and agents who need to know such information in 
connection with the transactions described herein and the other Transaction 
Documents (each of whom shall be informed of this confidentiality provision 
and in respect of whose breaches the Company shall be responsible)) the 
content of this Agreement or any of the other Transaction Documents or the 
substance of the transactions described herein, without the prior written 
consent of EIS (which consent shall not be unreasonably withheld or delayed), 
except to the extent required by applicable laws or administrative or judicial 
processor in respect of press releases and periodic reports prepared in good 
faith by the Company; provided, that the Company shall provide EIS with a 
reasonable opportunity to review and approve such releases or reports.  This 
Section 4 shall not be construed to prohibit disclosure of any information 
which has not been previously determined to be confidential by EIS, or which 
shall have become publicly disclosed (other than by breach of the Company's 
obligations hereunder).

(b)   Board of Directors.  Coincident with Closing, the Company's board of 
directors shall be expanded by one member, from seven to eight members, and EIS 
shall be entitled to appoint a director to fill the vacancy so created (the 
"EIS Director"), who shall be a duly elected director.  From and after the 
date hereof and for so long as EIS and/or their respective affiliates own 
Securities that represent ownership of at least 5% (and 10% from and after 
October 15, 2004) of the Common Stock, on a  fully diluted basis the Company 
shall use its best efforts to cause the EIS Director to be elected to the 
Company's board of directors, by including the EIS Director in the management 
slate of directors at each meeting of stockholders at which an election of 
directors occurs.  Appointment of the EIS Director shall be subject to the 
consent of the Company, which shall not be unreasonably withheld or delayed, 
and which shall be based upon regulatory and fitness of character 
considerations.

(c)  Fully-diluted Stock Ownership.  Notwithstanding any other provision of 
this Agreement, in the event that EIS shall have determined that at any time 
it (together with its Affiliates, if applicable) holds or has the right to 
receive Common Stock (or securities or rights, options or warrants 
exercisable, exchangeable or convertible for or into Common Stock) 
representing in the aggregate in excess of 19.9% of the Company's outstanding 
Common Stock (assuming any such exercise, exchange or conversion, but not the 
exercise, exchange or conversion of any other similar securities), EIS shall 
have the right, in its sole discretion, rather than acquiring such securities 
from the Company, to exchange such number of securities, as are necessary to 
bring its holdings to below 19.9% of the voting securities of the Company, for 
non-voting, liquidation preference equity securities of the Company (which 
shall be reasonably satisfactory to the Company and EIS), which equity 
securities shall be entitled to all of the other rights and benefits of the 
Common Stock.  In the event that EIS shall undertake to exercise such right, 
EIS shall retain the additional right to exchange such new class of equity 
security for Common Stock, in its discretion.

(d)   Certain Prohibited Activities.  (i) For such time that the Promissory 
Note remains outstanding, the Company shall not, without EIS's written consent 
(which consent will not be unreasonably withheld or delayed): (a) acquire or 
dispose of  any material asset or business, other than in the ordinary course 
of business; (b) merge or consolidate with any other corporation or acquire 
control of any other corporation or business entity; or (c) incur any 
indebtedness or liens outside the ordinary course of business, which  ordinary 
course shall include equipment leases and working capital lines up to a 
maximum of the lesser of $5 million and 50% of  the Company's aggregate 
consolidated accounts receiveable and inventory;

(ii) In the event that Stockholder Approval is obtained, and after the 
redemption of the Promissory Note and issuance and sale of the Preferred Stock 
has occurred, the restrictions referred to in item (a) of Section 4(d) above 
shall continue, and the restrictions referred to in items (b) and  (c) above 
shall be of no further force or effect; provided that, they shall be replaced 
by the following restriction: without the written consent of EIS (which 
consent will not be unreasonably withheld or delayed) the Company shall not 
incur any indebtedness in excess of $10 million aggregate principal amount 
unless the Company can reasonably establish (based on prudent and customary 
commercial practices and standards in the capital markets) that the Company 
may incur such indebtedness from an institutional lender, venture capital firm 
or reputable so-called "hedge" fund, on a prudent and reasonable basis, based 
on the Company's then credit-worthiness, prospects, solvency and business 
(each of item (a) and (b) of Section 5(e)(i) and this Section 5(e)(ii), as 
applicable, a "Restricted Transaction").  Notwithstanding the foregoing, the 
Company may incur working capital lines and equipment leases from unaffiliated 
third parties in bona fide financing transactions in principal amounts up to 
the lesser of $5 million and 50% of the Company's aggregate consolidated 
accounts receivable and inventory.

(e) Stockholder Approval.  The Company shall prepare a Proxy Statement, call a 
Special Meeting of Stockholders to be held prior to February 1, 1998, and use 
its best efforts (including, without limitation, subject to their fiduciary 
duties as directors, the board of director affirmative recommendation that the 
stockholders of the Company vote to approve issuance and sale of the Series A 
and Series B Preferred Stock in exchange for the Promissory Note), all to the 
fullest extent permitted and as required under applicable law, to obtain 
thereat the approval (the "Stockholder Approval") of the proposal to issue and 
sell the Series A and Series B Preferred Stock and to authorize the issuance 
of the Series C Preferred Stock and amend the Company's Articles of 
Incorporation in connection therewith in  exchange for the Promissory Note 
(the "Proposal").  In the event that the Stockholders' Approval shall not have 
been obtained on or prior to February 1, 1998, EIS shall be entitled, in their 
sole discretion and upon at least 30-days notice to the Company, to consider 
such lack of approval as a rejection of the Proposal.  The Company shall 
provide a draft copy of such Proxy Statement to EIS at least five business 
days prior to the anticipated date of filing with the SEC, and the filing of 
the Proxy Statement shall be subject to EIS's approval thereof, which shall 
not be unreasonably withheld or delayed.

(f) Use of Proceeds.  The Company shall use the proceeds of the sale of  the 
Series C Preferred Stock, if any, solely for the purpose of meeting its 
capitalization and funding requirements to Newco, described as Additional 
Funding in the Bioject JV Subsidiary Inc. Subscription and Stockholder 
Agreement dated as of the date hereof.

SECTION 5.  Mutual Covenants of the Parties.  (a) Exchange.  In the event that 
Stockholder Approval is obtained, EIS shall tender the Promissory Note to the 
Company in exchange for the issuance to EIS of (i) that number of shares of 
the Series A Preferred Stock equal to (a) $10 million plus accrued and unpaid 
interest divided by (b) $15, and (ii) 134,333 shares of the Series B Preferred 
Stock such tender and exchange to be completed within 10 business days of the 
date of Stockholder Approval.

(b) Further Assurances.  From and after the date hereof, each of the parties 
hereto agree to do or cause to be done such further acts and things and 
deliver or cause to be delivered to each other such additional assignments, 
agreements, powers and instruments, as each may reasonably require or deem 
advisable to carry into effect the purposes of the Transaction Documents or to 
better to assure and confirm unto each other their respective rights, powers 
and remedies hereunder and thereunder.

(c) Preferred Stock Early Redemption.  In the event that the Company desires 
to engage in a Restricted Transaction to which EIS has reasonably withheld its 
consent (s provided herein), the Company shall have the right to redeem the 
remaining outstanding Preferred Stock, by paying to EIS the amount of unpaid 
dividends then accrued and unpaid, and issuing to EIS  a warrant (the 
"Contingent Warrant") in customary form and otherwise reasonably satisfactory 
to EIS which shall entitle EIS to purchase that number of shares of Common 
Stock (or securities or other property of its successor or acquirer, if any, 
in accordance with the Anti-Dilution Adjustments) into which the Preferred 
Stock would have been convertible had it not been redeemed under this 
provision, at an aggregate price equal to the sum of the entire amount of the 
Preferred Stock and an interest component on such sum of 9% per annum from 
redemption until the date of exercise.   The Contingent Warrant shall be 
transferable in accordance with Section 16 hereof.

(d) Technology Collaboration.  (i) Each of the parties hereto agree that 
commencing with the first quarter of 1998, upon written request from the 
Company, EIS shall cause to be invested up to $500,000 in the form of grants 
to the Company in support of the development of the Company's existing needle-
free injection technologies (the "Technology Collaboration") in four equal, 
quarterly (in arrears) payments of $125,000 each.

(ii) The first such technology referred to in Section 5(e)(i) shall be one or 
more pre-filled ampule projects mutually acceptable to EIS and the Company; 
and that other projects may be substituted on a mutually satisfactory basis if 
it is determined by the Company that the initial projects have no practical 
commercial potential.

(iii) All intellectual property and results of projects shall belong to the 
Company; provided, that EIS shall have a right of first refusal, on then-
current market terms, to conduct further development or commercialization of 
such intellectual property or results in conjunction with the Company, for the 
period of one year following completion of work directly funded by the grants 
contemplated herein.  During such one-year period, the Company shall not take 
any actions, including in concert with any third party, which would negatively 
effect EIS's right.

(e) Standstill.  EIS agrees that, for a period of three years from the date 
hereof, unless (i) a party shall have been specifically invited in writing by 
the Company or (ii) a party unaffiliated with EIS, without participation or 
encouragement of EIS or any of its affiliates (as such term is defined under 
the Securities Exchange Act of 1934 (the "1934 Act")), shall announce a tender 
offer or solicit proxies with respect to an acquisition proposal which has not 
been solicited by the Company's board of directors or attempts to control the 
management or business or affairs of the Company or otherwise acquire more 
than 10% of the Company's voting securities (outright or on an as converted 
basis; without approval from the Company's Board of Directors), neither EIS 
nor its affiliates shall in any manner, directly or indirectly, (a) effect or 
seek, offer or propose to effect or participate in (publicly or otherwise) (i) 
any acquisition of securities (or beneficial ownership thereof) or assets of 
the Company or its subsidiaries, (ii) any tender or exchange offer, merger or 
other business combination involving the Company or any of its subsidiaries, 
(iii) any recapitalization, restructuring, liquidation, dissolution or other 
extraordinary transaction with respect to the Company or its subsidiaries, or 
(iv) any solicitation of proxies (as such terms are defined under the 
regulations of the Securities and Exchange Commission) or consents to vote any 
voting securities of the Company; (b) form, join or participate in a group (as 
defined under the 1934 Act); (c) otherwise act to seek control or influence 
the management, board of directors or policies of the Company, or (d) take any 
action which may force the Company to make a public announcement regarding any 
matters enumerated in (a) above.

SECTION 6.  Entire Agreement.  This Agreement and the other Transaction 
Documents contain the entire understanding of the parties with respect to the 
subject matter hereof and supersede all prior agreements and understandings 
among the parties with respect thereto.

SECTION 7.  Survival and Indemnification.  (a) Survival Period.  The 
representations and warranties of the Company contained herein shall survive 
for a period of one year after the date hereof.  

(b)  Indemnification.  In addition to all rights and remedies available to the 
parties hereunder at law or in equity, the Company (in such capacity, an 
"Indemnifying Party") shall indemnify EIS, and its respective affiliates, and 
EIS' and its respective affiliates' stockholders, officers, directors, 
employees, agents, representatives, successors and assigns (collectively, the 
"Indemnified Person"), and save and hold EIS harmless from and against and pay 
on behalf of or reimburse each such Indemnified Person, as and when incurred, 
for any and all loss, liability, demand, claim, action, cause of action, cost, 
damage, deficiency, tax, penalty, fine or expense, whether or not arising out 
of any claims by or on behalf of such Indemnified Person or any third party, 
including interest, penalties, reasonable attorneys' fees and expenses and all 
amounts paid in investigation, defense or settlement of any of the foregoing 
(collectively, "Losses"), that any such Indemnified Person may suffer, sustain 
incur or become subject to, as a result of, in connection with, relating or 
incidental to or by virtue of:

(i) any misrepresentation or breach of warranty on the part of the 
Indemnifying Party under Section 2 of this Agreement; or

(ii) any nonfulfillment, default or breach of any covenant or agreement on the 
part of the Indemnifying Party under Section 4 of this Agreement. 


(c)   Maximum Recovery.  The maximum recovery of EIS under this Section 7 
shall not exceed $15 million.  No Indemnified Party shall assert any such 
claim unless Losses in respect thereof incurred by any Indemnified Party, when 
aggregated with all previous Losses hereunder, equal or exceed $250,000, and 
the obligation of the Indemnifying Party to indemnify shall not apply to the 
first $250,000 of losses to the Indemnified Person.

(d)   Exception.  Notwithstanding the foregoing, and subject to the following 
sentence, upon judicial determination that is final and no longer appealable, 
that the act or omission giving rise to the indemnification set forth above 
resulted primarily out of or was based primarily upon the Indemnified Person's 
negligence(unless such Indemnified Person's negligence was based upon the 
Indemnified Persons reliance in good faith upon any of the representations, 
warranties, covenants or promises made by the Indemnifying Party herein) the 
Indemnifying Party shall not be responsible for any Losses sought to be 
indemnified in connection therewith, and the Indemnifying Party shall be 
entitled to recover from the Indemnified Persons all amounts previously paid 
in full or partial satisfaction of such indemnity, together with all costs and 
expenses (including reasonable attorneys fees) of the Indemnifying Party 
reasonably incurred in connection with the Indemnified Party's claim for 
indemnity, together with interest at the rate per annum publicly announced by 
Morgan Guaranty Trust Company as its prime rate from the time of  payment of 
such amounts to the Indemnified Person until repayment to the Indemnifying 
Party.

(e)  Investigation.  All indemnification rights hereunder shall survive the 
execution and delivery of this Agreement and the consummation of the 
transactions contemplated hereby to the extent provided in Section 7(b) above, 
irrespective of any investigation, inquiry or examination made for or on 
behalf of, or any knowledge of the Indemnified Persons or the acceptance of 
any certificate or opinion. 

(f)   Contribution.  If the indemnity provided for the this Section 7 shall 
be, in whole or in part, unavailable to any Indemnified Person, due to Section 
7(b) being declared unenforceable by a court of competent jurisdiction based 
upon reasons of public policy, so that Section 7(b) shall be insufficient to 
hold each such Indemnified Person harmless from Losses which would otherwise 
be indemnified hereunder, then the Indemnifying Party and the Indemnified 
Person shall each contribute to the amount paid or payable for such Loss in 
such proportion as is appropriate to reflect not only the relative benefits 
received by the Indemnifying Party on the one hand and the Indemnified Person 
on the other, but also the relative fault of the Indemnifying Party and be in 
addition to any liability that the Indemnifying Party may otherwise have.  
Subject to Section 7(h) hereunder, the indemnity, contribution and expense 
reimbursement obligations that the Indemnifying Party has under this Section 7 
shall survive the expiration of the Transaction Documents.  The parties hereto 
further agree that the indemnification and reimbursement commitments set forth 
in this Agreement shall apply whether or not the Indemnified Person is a 
formal part to any such lawsuit, claims or other proceedings.

(g)  Limitation.  No claim shall be brought by an Indemnified Person in 
respect of any misrepresentation or breach of warranty under this Agreement 
after one year from and after the date hereof; and any claim for 
nonfulfillment, default or breach of any covenant shall be brought within one 
year of the date of that such Indemnified Person became aware or should have 
become aware of the nonfulfillment, default or breach.  Except as set forth in 
the previous sentence and in Section 7(c) above, this Section 7 is not 
intended to limit the rights or remedies otherwise available to any party 
hereto with respect to this Agreement or the Transaction Documents.

SECTION 8.  Notices.  All notices, demands and requests of any kind to be 
delivered to any party in connection with this Agreement shall be in writing 
and shall be deemed to have been duly given if personally delivered or if sent 
by nationally-recognized overnight courier or by registered or certified 
airmail, return receipt requested and postage prepaid, or by facsimile 
transmission, addressed as follows:

(i) if to the Company, to:

Bioject Medical Technologies, Inc.
7620 S.W. Bridgeport Road
Portland, Oregon
Facsimile: 503-620-6431
Attention: James C. O'Shea

with a copy to:

Bogle and Gates P.L.LC.
Two Union Square
601 Union St.
Seattle, WA 98101
Facsimile: (206) 621-2660
Attn: Christopher Barry

(ii) if to EIS, to:
Elan International Services, Ltd.

Flatts Smiths SL04
Bermuda
Facsimile: (441) 292-2224
Attention: President

with a copy to:
Brock Fensterstock Silverstein McAuliffe & Wade LLC
153 East 53rd Street 
New York, New York 10022
Facsimile: (212) 371-5500
Attention: David Robbins

or to such other address as the party to whom notice is to be given may have 
furnished to the other party hereto in writing in accordance with provisions 
of this Section 8.  Any such notice or communication shall be deemed to have 
been received (i) in the case of personal delivery or facsimile transmission, 
on the date of such delivery, (ii) in the case of nationally-recognized 
overnight courier, on the second business day after the date when sent and 
(iii) in the case of mailing, on the fifth business day following that day on 
which the piece of mail containing such communication is posted.  Notice 
hereunder may be given on behalf of the parties by their respective attorneys.

SECTION 9.  Withholding Taxes.  Amounts of income or other taxes 
which the Company is required by law to pay or withhold with respect to 
payments or distributions made by it to EIS pursuant to the terms of this 
Agreement and the Securities (the "Tax Amount") shall be deducted from such 
payment or distribution.  In the event that such a distribution made in 
property other than cash would require the Company by law to pay or withhold 
income taxes, prior to such distribution the Company shall advise EIS of the 
Tax Amount, and EIS shall promptly remit such Tax Amount to the Company in 
cash and the Company shall make such distribution of property to EIS, and in 
such event, the Company will (i) promptly pay the Tax Amount to the relevant 
taxing authority and (ii) provide to EIS such documentation necessary to 
permit EIS to reclaim the Tax Amount as a Foreign Tax Credit.  Notwithstanding 
the foregoing, the Company shall not withhold, and EIS shall not be required 
to pay, the Tax Amount if (i) EIS shall determine in good faith that on the 
basis of a written opinion of an independent tax advisor that there is 
substantial authority to determine that the Company is not required to 
withhold the Tax Amount and (ii) EIS shall agree in writing to indemnify the 
Company from and against all liability arising from a failure to pay or 
withhold the Tax Amount, including without limitation the Tax Amount, and any 
interest or penalty assessed thereon by such taxing authority.  It shall be a 
condition to any assignment of any Security that the assignee thereof be bound 
by this Section 9.

SECTION 10.  Amendments.  This Agreement may not be modified or 
amended, or any of the provisions hereof waived, except by written agreement 
of the Company and EIS.

SECTION 11.  Counterparts and Facsimile.      The Transaction 
Documents may be executed in any number of counterparts, and each such 
counterpart hereof shall be deemed to be an original instrument, but all such 
counterparts together shall constitute one agreement.  Each of the Transaction 
Documents may be signed and delivered to the other party by facsimile 
transmission; such transmission shall be deemed a valid signature.

SECTION 12.  Headings.  The section and paragraph headings 
contained in this Agreement are for reference purposes only and shall not 
affect in any way the meaning or interpretation of the Agreement.

SECTION 13.  Governing Law.  This Agreement shall be governed by 
and construed in accordance with the laws of the State of Oregon, without 
giving effect to principles of conflicts of laws.

SECTION 14.  Expenses.  Each of the parties shall be responsible 
for its own costs and expenses incurred in connection with the transactions 
contemplated hereby and by the other Transaction Documents.

SECTION 15.  Public Releases; Etc.  The parties shall reasonably 
agree upon the contents of any press release or releases and other public 
disclosure in respect of the transactions contemplated hereby, and except as 
may otherwise be required by applicable law or judicial or administrative 
process or which the Company concludes in good faith is required by applicable 
securities laws and regulations.

SECTION 16.  Schedules, etc.  All statements contained in any 
exhibit or schedule delivered by or on behalf of the parties hereto, or in 
connection with the transactions contemplated hereby, are an integral part of 
this Agreement and shall be deemed representations and warranties hereunder.


SECTION 17.  Assignments.  This Agreement and all of the 
provisions hereof shall be binding upon and inure to the benefit of the 
parties hereto and their respective successors and permitted assigns.  This 
Agreement, the other Transaction Documents, and the Securities may be 
transferred by EIS to affiliates and subsidiaries without restriction, and in 
addition,  to five non-affiliated institutions, who are accredited investors 
(as that term is defined under Regulation D of the Securities Act of 1933).


[Signature page follows]




IN WITNESS WHEREOF, each of the undersigned has duly executed this 
Securities Purchase Agreement as of the date first written above.


Bioject Medical Technologies Inc.


By:/s/ James C. O'Shea                        
Name:  James C. O'Shea
Title: President

Elan International Services, Ltd.


By:/s/ Kevin Insley                         
Name:  Kevin Insley
Title: President and Chief Financial Officer






                                                               EXHIBIT 10.42

                     BIOJECT MEDICAL TECHNOLOGIES, INC.
                       REGISTRATION RIGHTS AGREEMENT

THIS REGISTRATION RIGHTS AGREEMENT is made as of October 15, 1997, by and 
among Bioject Medical Technologies Inc., an Oregon corporation (the 
"Company"), and Elan International Services, Ltd., a Bermuda corporation 
("EIS").



R E C I T A L S:

A. Pursuant to a Securities Purchase Agreement dated as of the date hereof 
(the "Purchase Agreement"),  EIS has acquired (x) certain shares of common 
stock without par value (the "Common Stock") of the Company and a warrant to 
purchase up to 1,750,000 shares (subject to adjustment) of Common Stock (the 
"Warrant"), and (y) a promissory note (the Promissory Note"), which under 
certain circumstances  shall be exchanged by EIS for shares of two series of 
preferred stock (the "Preferred Stock"), which Preferred Stock may be 
convertible into shares of Common Stock. 

B. The closing under the Purchase Agreement has occurred on the date hereof; 
it being a condition to such closing that the parties execute and deliver this 
Agreement.

C. The parties desire to set forth herein their agreement related to the 
granting of certain registration rights to the Holders (as defined below) of 
any Common Stock or securities convertible into Common Stock.


       A G R E E M E N T:

The parties hereto agree as follows:

1. Certain Definitions.  As used in this Agreement, the following terms shall 
have the following respective meanings:

"Affiliate" of any Person shall mean any other Person controlling, 
controlled by or under common control with such particular Person.  In the 
case of a natural Person, his Affiliates include members of such Person's 
immediate family, natural lineal descendants of such Person or a trust for the 
exclusive benefit of such Person and his immediate family and natural lineal 
descendants.

"Commission" shall mean the Securities and Exchange Commission or any other 
federal agency at the time administering the Securities Act.

"Holders", "holders" or "Holders of Registrable Securities" shall mean 
EIS and any Person who shall have acquired Registrable Securities from EIS as 
permitted herein pursuant to Section 9 hereof, either individually or jointly 
as the case may be.

"Person" shall mean an individual, a partnership, a company, an association, 
a joint stock company, a trust, a joint venture, an unincorporated 
organization and a governmental quasi-governmental entity or any department, 
agency or political subdivision thereof.

"Registrable Securities" means (i) any Common Stock issued or issuable under 
the Purchase Agreement and the Warrant, (ii) any Common Stock issued or 
issuable upon conversion of or in connection with the holding of the Preferred 
Stock , (iii) any Common Stock issued or issuable in respect of the securities 
referred to in clauses (i) or (ii) above upon any stock split, stock dividend, 
recapitalization or similar event, and (iv) any other stock acquired by EIS or 
its affiliates from the Company; excluding in all cases, however, any 
Registrable Securities sold by a Person in a transaction (including a  
transaction pursuant to a registration statement under this Agreement and 
transaction pursuant to Rule 144 promulgated under the Securities Act) in 
which registration rights are not transferred pursuant to Section 9 hereof.

The terms "register," "registered" and "registration" refer to a 
registration effected by preparing and filing a registration statement in 
compliance with the Securities Act, and the declaration or ordering of the 
effectiveness of such registration statement.

"Registration Expenses" shall mean all expenses, other than Selling 
Expenses, incurred by the Company in complying with Sections 2 or 3 hereof, 
including without limitation, all registration, qualification and filing fees, 
exchange listing fees, printing expenses, escrow fees, fees and disbursements 
of counsel for the Company, blue sky fees and expenses, the expense of any 
special audits incident to or required by any such registration and the 
reasonable fees and disbursements, not to exceed $10,000 in the aggregate, of 
one counsel for the Holders, such counsel to be selected by Holders holding a 
majority of the Registrable Securities held by the Holders and included in 
such registration.

"Securities Act" shall mean the Securities Act of 1933, as amended, or any 
similar federal statute and the rules and regulations of the Commission 
thereunder, all as the same shall be in effect at the time.

"Selling Expenses" shall mean all underwriting discounts, selling 
commissions and stock transfer taxes applicable to the securities registered 
by the Holders and the costs of any accountants, counsel or other experts 
retained by the Holders.

"1934 Act" shall mean the Securities Exchange Act of 1934, as amended, or 
any similar federal statute and the rules and regulations of the Commission 
thereunder, all as the same shall be in effect at the time.

 2. Demand Registrations.  (a) Requests for Registration.  Any Holder which 
holds Registrable Securities representing at least the majority of the 
Registered Securities then outstanding has the right at any time from time to 
time, to request registration under the Securities Act of all or part of their 
Registrable Securities on Form S-1, S-2 or S-3 (if available) or any similar 
registration (each, a "Demand Registration"), such form to be selected by 
the Company, it being understood that the Company is not required to file a 
registration statement with respect to common stock not deemed outstanding 
within the meaning of General Instruction I.B.3. of Form S-3.  Each written 
request for a Demand Registration (as defined below) shall specify the 
approximate number of Registrable Securities requested to be registered.  
Within 10 days after receipt of any such request, the Company will give 
written notice of such requested registration to all other Holders of 
Registrable Securities and, if they request to be included in such 
registration, the Company shall include such Holders' Registrable Securities 
in such offering if they have responded affirmatively within 10 days after the 
receipt of the Company's notice. The Holders in aggregate will be entitled to 
request two Demand Registrations.  A registration will not count as one of the 
permitted Demand Registrations until it has become effective (unless such 
Demand Registration has not become effective due solely to the fault of the 
Holders requesting  such registration, including a request by such Holders 
that such registration be withdrawn).  In the event that a the Holders shall 
exercise their right to Demand Registration under this section, and such 
Demand Registration shall be underwritten, the Company and the Holders 
exercising such right shall bear the costs associated with the underwritten 
registration on an equal basis.  The Company shall be liable for payment of 
all expenses associated with any Demand Registrations which are not 
underwritten in accordance with the terms hereof.

(b) Priority on Demand Registrations.  If a Demand Registration is an 
underwritten offering and the managing underwriters advise the Company in 
writing that in their opinion the number of Registrable Securities and, if 
permitted hereunder, other securities requested to be included in such 
offering, exceeds the number of Registrable Securities and other securities, 
if any, which can be sold in such offering without adversely affecting the 
marketability of the offering, the Company will include in such registration:

(i) first, the Registrable Securities requested to be included in such 
registration by the Holders (or, if necessary, such Registrable Securities pro 
rata among the Holders thereof based upon the number of Registrable Securities 
owned by each such Holder) together with any securities held by third parties 
holding a similar, previously granted right to be included in such 
registration; and 

(ii) thereafter, other securities requested to be included in such 
registration.

(c) Restrictions on Demand Registrations.  The Company may postpone for up to 
six months in any 12-month period, the filing or the effectiveness of a 
registration statement for a Demand Registration if the Company determines in 
good faith that such Demand Registration would reasonably be expected to have 
a material adverse effect on any proposal or plan by the Company to engage in 
any financing, acquisition or disposition of assets (other than in the 
ordinary course of business) or any merger, consolidation, tender offer or 
similar transaction or would require disclosure of any information that the 
board of directors of the Company determines in good faith the disclosure of 
which would be detrimental to the Company; provided, that in such event, the 
Holders initially requesting such Demand Registration will be entitled to 
withdraw such request and, if such request is withdrawn, such Demand 
Registration will not count as one of the permitted Demand Registrations 
hereunder and the Company will pay any Registration Expenses in connection 
with such withdrawn registration.

(d) Selection of Underwriters.  The Holders will have the right to select the 
investment banker(s) and manager(s) to administer an offering pursuant to a 
Demand Registration, subject to the Company's approval, which will not be 
unreasonably withheld.

(e) Other Registration Rights.  Except as provided in this Agreement, so long 
as any Holder owns any Registrable Securities, the Company will not grant to 
any Persons the right to request the Company to register any equity securities 
of the Company, or any securities convertible or exchangeable into or 
exercisable for such securities, which is in conflict with the rights granted 
to the Holders hereunder, without the prior written consent of the Holders of 
at least 50% of the Registrable Securities held by the Holders; it being 
understood that the Company may grant rights to other Persons to (i) 
participate in Piggyback Registrations so long as such rights are subordinate 
or pari passu to the rights of the holders of Registrable Securities with 
respect to such Piggyback Registrations and (ii) request registrations so long 
as the Holders of Registrable Securities are entitled to participate in any 
such registrations with such Persons pro rata on the basis of the number of 
shares owned by each such Holder. 

3. Piggyback Registrations.  (a) Right to Piggyback.  At any time the Company 
shall propose to register Common Stock under the Securities Act (other than in 
a registration on Form S-3 relating to sales of securities to participants in 
a Company dividend reinvestment plan, S-4 or S-8 or any successor form or in 
connection with an acquisition or exchange offer or an offering of securities 
solely to the existing stockholders or employees of the Company) (each, a 
"Piggyback Registration"), the Company will give prompt written notice to 
all Holders of Registrable Securities of its intention to effect such a 
registration and, subject to Section 3(b) and the other terms of this 
Agreement, will include in such registration all Registrable Securities which 
are permitted under applicable securities laws to be included in the Form of 
registration statement selected by the Company and with respect to which the 
Company has received written requests for inclusion therein within 15 days 
after the receipt of the Company's notice.

(b) Priority on Piggyback Registrations.  If a Piggyback Registration is an 
underwritten registration of Common Stock, and the managing underwriters 
advise the Company in writing that in their opinion the number of securities 
requested to be included in such registration exceeds the number which can be 
sold in such offering without adversely affecting the marketability of the 
offering, the Company will include in such registration:

(i) the securities the Company proposes to sell;

(ii) any securities having the right to be included in such registration prior 
to the securities of the Holders, provided that such registration right shall 
have existed prior to the date hereof; 

(iii) the Registrable Securities requested to be included in such registration 
by the Holders and such other Persons and any securities requested to be 
included in such registration by any other Person, pro rata among the Holders 
of such Registrable Securities and such other Persons, on the basis of the 
number of shares owned by each of such Holders subject to the rights of such 
other Persons under agreements existing as of the date hereof; and

(iv) thereafter, other securities requested to be included in such 
registration.

The Holders of any Registrable Securities included in such a registration must 
execute an underwriting agreement in form and substance satisfactory to the 
managing underwriters.

(c) Right to Terminate Registration.  If, at any time after giving written 
notice of its intention to register any of its securities as set forth in 
Section 3(a) and prior to the effective date of the registration statement 
filed in connection with such registration, the Company shall determine for 
any reason not to register such securities, the Company may, at its election, 
give written notice of such determination to each Holder of Registrable 
Securities and thereupon be relieved of its obligation to register any 
Registrable Securities in connection with such registration (provided that the 
Company shall pay the Registration Expenses in connection therewith).

(d) Selection of Underwriters.  The Company will have the right to select the 
investment banker(s) and manager(s) to administer an offering pursuant to a 
Piggyback Registration.

4. Expenses of Registration.  Subject to the final sentence of Section 2(a), 
Registration Expenses incurred in connection with all registrations pursuant 
to Section 2 shall be borne by the Company.  All Selling Expenses relating to 
securities registered on behalf of the Holders of Registrable Securities shall 
be borne by such holders.  Registration expenses incurred in connection with 
registration pursuant to Section 3 shall be borne by the Company and the 
Holders on a pro rata basis in accordance with the number of Shares sold by 
each. 

5. Holdback Agreements.   (a) The Company agrees (i) not to effect any public 
offering, sale or distribution of its equity securities, or any securities 
convertible into or exchangeable or exercisable for such securities, during 
the seven days prior to and during the 90-day period beginning on the 
effective date of any underwritten Demand Registration or any underwritten 
Piggyback Registration (except as part of such underwritten registration or 
pursuant to registrations on Form S-8 or any successor form), unless the 
underwriters managing the registered public offering otherwise agree, and (ii) 
to use reasonable efforts to cause each holder of at least 5% (on a fully-
diluted basis) of its Common Stock, or any securities convertible into or 
exchangeable or exercisable for Common Stock, purchased from the Company at 
any time after the date of this Agreement (other than in a registered public 
offering) to agree not to effect any public sale or distribution (including 
sales pursuant to Rule 144) of any such securities during such periods (except 
as part of such underwritten registration, if otherwise permitted), unless the 
underwriters managing the registered public offering otherwise agree.

 (b) Each holder of Registrable Securities agrees, if requested by the 
managing underwriter or underwriters in an underwritten offering of securities 
of the Company, not to effect any offer, sale, distribution or transfer (or 
offer or agree to do so) of Registrable Securities, including a sale pursuant 
to Rule 144 (or any similar provision then effect) under the Securities Act 
(except as part of such underwritten registration), during the seven-day 
period prior to, and during the 90-day period or such shorter period as may be 
agreed to by the parties hereto) following the effective date of such 
Registration Statement to the extent timely notified in writing by the Company 
or the managing underwriter or underwriters.

6.  Registration Procedures.  Whenever the Holders of Registrable Securities 
have requested that any Registrable Securities be registered pursuant to this 
Agreement, the Company will use its best efforts to effect the registration 
and the sale of such Registrable Securities in accordance with the intended 
method of distribution thereof, and pursuant thereto the Company will as 
expeditiously as possible:

(a) subject to Section 2(c) hereof, prepare and file with the Commission a 
registration statement on any form for which the Company qualifies with 
respect to such Registrable Securities and use its best efforts to cause such 
registration statement to become effective (provided that before filing a 
registration statement or prospectus or any amendments or supplements thereto, 
the Company will (i) furnish to the counsel selected by the Holders copies of 
all such documents proposed to be filed, which documents will be subject to 
the review of such counsel, and (ii) notify each holder of Registrable 
Securities covered by such registration of any stop order issued or threatened 
by the Commission);

(b) subject to Section 2(c) hereof, prepare and file with the Commission such 
amendments and supplements to such registration statement and the prospectus 
used in connection therewith as may be necessary to keep such registration 
statement effective for a period of not less than nine months and comply with 
the provisions of the Securities Act with respect to the disposition of all 
securities covered by such registration statement during such period in 
accordance with the intended methods of disposition by the sellers thereof set 
forth in such registration statement;

(c) furnish to each seller of Registrable Securities such number of copies of 
such registration statement, each amendment and supplement thereto, the 
prospectus included in such registration statement (including each preliminary 
prospectus) and such other documents as such seller may reasonably request in 
order to facilitate the disposition of the Registrable Securities owned by 
such seller;

(d) use its best efforts to register or qualify such Registrable Securities 
under such other securities or blue sky laws of such jurisdiction  as any 
seller reasonably requests and do any and all other acts and things which may 
be reasonably necessary or advisable to enable  such seller to consummate the 
disposition in such jurisdictions of the Registrable Securities owned by such 
seller (provided that the Company will not be required to (i) qualify 
generally to do business in any jurisdiction where it would not otherwise be 
required to qualify but for this Section 6(d), (ii) subject itself to taxation 
in any jurisdiction or (iii) consent to general service of process in any such 
jurisdiction);

(e) notify each seller of such Registrable Securities, at any time when a 
prospectus relating thereto is required to be delivered under the Securities 
Act, of the happening of any event as a result of which the prospectus 
included in such registration statement contains an untrue statement of a 
material fact or omits any fact necessary to make the statements therein not 
misleading, and, at the request of any such seller, the Company will prepare a 
supplement of amendment to such prospectus so that, as thereafter delivered to 
the purchasers of such Registrable Securities, such prospectus will not 
contain an untrue statement of a material fact or omit to state any fact 
necessary to make the statements therein not misleading; provided that the 
Company shall not be required to amend the registration statement or 
supplement the Prospectus for a period of up to six months if the board of 
director determines in good faith that to do so would reasonably be expected 
to have a material adverse effect on any proposal or plan by the Company to 
engage in any financing, acquisition or disposition of assets (other than in 
the ordinary course of business) or any merger, consolidation, tender offer or 
similar transaction or would require the disclosure of any information that 
the board of directors determines in good faith the disclosure of which would 
be detrimental to the Company, it being understood that the period for which 
the Company is obligated to keep the Registration Statement effective shall be 
extended for a number of days equal to the number of days the Company delays 
amendments or supplements pursuant to this provision.  Upon receipt of any 
notice pursuant to this section 6(e) Holders shall suspend all offers and 
sales of securities of the Company and all use of any prospectus until advised 
by the Company that offers and sales may resume, and shall keep confidential 
the fact and content of any notice given by the Company pursuant to this 
section 6(e)   

(f) cause all such Registrable Securities to be listed on each securities 
exchange on which similar securities issued by the Company are then listed 
and, if not so listed, to be listed on the NASD automated quotation system 
and, if listed on the NASD automated quotation system, use its best efforts to 
secure designation of all such Registrable Securities covered by such 
registration statement as a NASDAQ National market system security within the 
meaning of Rule 11Aa2-1 of the Commission or, failing that, to secure NASDAQ 
authorization for such Registrable Securities and, without limiting the 
generality of the foregoing, to arrange for at least two market makers to 
register as such with respect to such Registrable Securities with the NASD;

(g) provide a transfer agent and registrar for all such Registrable Securities 
not later than the effective date of such registration statement;

(h) enter into such customary agreements (including underwriting agreements in 
customary form) and take all such other actions as the holders of a majority 
of the Registrable  Securities being sold or the underwriters, if any, 
reasonably request in order to expedite or facilitate the disposition of such 
Registrable Securities (including without limitation, effecting a stock split 
or a combination of shares);

(i) make available for inspection by a representative of the Holders of 
Registrable Securities included in the registration statement, any underwriter 
participating in any disposition pursuant to such registration statement and 
any attorney, accountant or other agent retained by any such seller or 
underwriter all pertinent financial and other records, pertinent corporate 
documents and properties of the Company, and cause the Company's officers, 
directors, employees and independent accountants to supply all information 
reasonable requested by any such seller, underwriter, attorney, accountant or 
agent in connection with such registration statement;

(j) otherwise use its reasonable efforts to comply with all applicable rules 
and regulations of the Commission, and make available to its security holders, 
as soon as reasonably practicable, an earnings statement covering the period 
of at least 12 months beginning with the first day of the Company's first full 
calendar quarter after the effective date of the registration statement, which 
earnings statement shall satisfy the provisions of Section 11(a) of the 
Securities Act and Rule 158 thereunder;

(k) in the event of the issuance of any stop order suspending the 
effectiveness of a registration statement, or of any order suspending or 
preventing the use of any related prospectus or suspending the qualification 
of any common stock included in such registration statement for sale in any 
jurisdiction, the Company will use its reasonable best efforts promptly to 
obtain the withdrawal of such order; and

(l) obtain a so-called "cold comfort" letter from the Company's independent 
public accountants in customary form and covering such matters of the type 
customarily covered by cold comfort letters.

7. Indemnification.  (a) The Company agrees to indemnify, to the fullest 
extent permitted by applicable law, each Holder of Registrable Securities, its 
officers and directors and each Person who controls such Holder (within the 
meaning of the Securities Act) against all losses, claims, damages, 
liabilities, expenses or any amounts paid in settlement of any litigation, 
investigation or proceeding commenced or threatened (collectively, "Claims") 
to which each such indemnified party may become subject under the Securities 
Act insofar as such Claim arose out of (i) any untrue or alleged untrue 
statement of material fact contained, on the effective date thereof, in any 
registration statement, prospectus or preliminary prospectus or any amendment 
thereof or supplement thereto or (ii) any omission or alleged omission to 
state therein a material fact required to be stated therein or necessary to 
make the statements therein not misleading, except insofar as the same are 
caused by or contained in any information furnished in writing to the Company 
by such holder expressly for use therein or by such holder's failure to 
deliver a copy of the registration statement or prospectus or any amendments 
or supplements thereto after the Company has furnished such holder with a 
sufficient number of copies of the same.  In connection with an underwritten 
offering, the Company will indemnify  such underwriters, their officers and 
directors and each Person who controls such underwriters (within the meaning 
of the Securities Act) to the same extent as provided above with respect to 
the indemnification of the holders of Registrable Securities.

(b) In connection with any registration statements in which a holder of 
Registrable Securities is participating, each such Holder will furnish to the 
Company in writing such customary information and affidavits as the Company 
reasonably requests for use in connection with any such registration statement 
or prospectus (the "Seller's Information") and, to the fullest extent 
permitted by applicable law will indemnify the Company, its directors and  
officers and each Person who controls the Company (within the meaning of the 
Securities Act) against any and all Claims to which each such indemnified 
party may become subject under the Securities Act insofar as such Claim arose 
out of (i) any untrue or alleged untrue statement of material fact contained, 
on the effective date thereof, in any  registration statement, prospectus or 
preliminary prospectus or any amendment thereof or supplement thereto, (ii) 
any omission or alleged omission to state therein a material fact required to 
be stated therein or necessary to make the statements therein not misleading 
or (iii) any violations by such Person of any federal, state or common law 
rule or regulation applicable to such Person and relating to action required  
of or inaction by such Person in connection with any such registration; 
provided that with respect to a Claim arising pursuant to clause (i) or (ii) 
above, the material misstatement or omission is contained in such Seller's 
Information; provided, further, that the obligation to indemnify will be 
individual to each Holder and will be limited to the net amount of proceeds 
received by such Holder from the sale of Registrable Securities pursuant to 
such registration statement.

(c) Any Person entitled to indemnification hereunder will (i) give prompt 
written notice to the indemnifying party of any claim with respect to which it 
seeks indemnification (but the failure to provide such notice shall not 
release the indemnifying party of its obligation under paragraphs (a) and (b), 
unless and then only to the extent that, the indemnifying party has been 
prejudiced by such failure to provide such notice) and (ii) unless in such 
indemnified party's reasonable judgment a conflict of interest between such 
indemnified  and indemnifying parties may exist with respect to such claim, 
permit such indemnifying party  to assume the defense of such claim with 
counsel reasonably satisfactory to the indemnified party.  An indemnifying 
party who is not entitled to, or elects not to, assume the defense of a claim 
will not be obligated to pay the fees and expenses of more than one counsel 
for all parties indemnified by such indemnifying party with respect to such 
claim, unless in the reasonable judgment of any indemnified party a conflict 
of interest may exist between such indemnified party and any other of such 
indemnified parties with respect to such claim.

(d) The indemnifying party shall not be liable to indemnify an indemnified 
party for any settlement, or consent to judgment of any such action effected 
without the indemnifying party's consent (but such consent will not be 
unreasonably withheld).  Furthermore,  the indemnifying party shall not, 
except with the approval of each indemnified party, consent to entry of any 
judgment or enter into any settlement which does not include as an 
unconditional term thereof the giving by the claimant or plaintiff to each 
indemnified party of a release from all liability in respect to such claim or 
litigation without any payment or consideration provided by each such 
indemnified party.

(e) If the indemnification provided for in this Section 7 is unavailable to an 
indemnified party under clauses (a) and (b) above in respect of any losses, 
claims, damages or liabilities referred to therein, then each indemnifying 
party, in lieu of indemnifying such indemnified party, shall contribute to the 
amount  paid or payable by such indemnified party as a result of such losses, 
claims, damages or liabilities in such proportion as is appropriate to reflect 
not only the relative benefits received by the Company, the underwriters, the 
sellers of Registrable Securities and any other sellers participating in the 
registration statement from the sale of shares pursuant to the registered 
offering of securities to which indemnity is sought but also the relative 
fault of the Company, the underwriters the sellers of Registrable Securities 
and any other sellers participating in the registration statement in 
connection with the statement or omissions which resulted in such losses, 
claims, damages or liabilities, as well as any other relevant equitable 
considerations.  The relative benefits received by the Company, the 
underwriters, the sellers of Registrable Securities and any other sellers 
participating in the registration statement shall be deemed to be based on the 
relative relationship of the total net proceeds from the offering (before 
deducting expenses) to the Company, the total underwriting  commissions and 
fees from the offering (before deducting expenses) to the underwriters and the 
total net proceeds from the offering (before deducting expenses) to the 
sellers of Registrable  Securities and any other sellers participating in the 
registration statement.  The relative fault of the Company, the underwriters, 
the sellers of Registrable Securities and any other sellers participating in 
the registration statement shall be determined by reference to, among other 
things, whether the untrue or alleged untrue statement of a material fact or 
the omission or alleged omission to state a material fact relates to 
information supplied by the Company or by registration statement and the 
parties' relative intent, knowledge, access to information and opportunity to 
correct or prevent such statement or omission.

(f) The indemnification provided for under this Agreement will remain in full 
force and effect regardless of any investigation made by or on behalf of the 
indemnified party or any officer, director or controlling person of such 
indemnified party and will survive the transfer of securities.

8. Participation in Underwritten Registrations.  No Person may participate in 
any registration hereunder which is underwritten unless such Person (a) agrees 
to sell such Person's securities on the basis provided in any underwriting 
arrangements approved by the Person or Persons entitled hereunder to approve 
such arrangements, (b) as expeditiously as possible notifies the Company of 
the occurrence of any event as a result of which such prospectus contains an 
untrue statement of material fact or omits to state a material fact required 
to be stated therein or necessary to make the statements therein not 
misleading and (c) completes and executes all questionnaires, powers of 
attorney, indemnities, underwriting agreements and other documents reasonably 
required under the terms  of such underwriting arrangements.

9. Transfer of Registration Rights.  The rights granted to any Person under 
this Agreement may be assigned to a transferee or assignee in connection with 
any transfer or assignment of Registrable Securities by a Holder; provided, 
that: (a)  such transfer may otherwise be effected in accordance with 
applicable securities laws, (b) if not already a party hereto, the assignee or 
transferee agrees in writing prior to such transfer to be bound by the 
provisions of this Agreement applicable to the transferor, (c) such transferee 
shall own Registrable Securities representing at least 1,000,000 shares of 
Common Stock, subject to the Anti-dilution Adjustments, and (d) EIS shall act 
as agent and representative for such Holder for the giving and receiving of 
notices hereunder.

10.  Information by Holder.  Each Holder shall furnish the Company such 
written information regarding such Holder and any distribution proposed by 
such Holder as the Company may reasonably request in writing and as shall be 
reasonably required in connection with any registration qualification or 
compliance referred to in this Agreement.

11.  Exchange Act Compliance.  After the IPO, the Company shall comply with 
all of the reporting requirements of the Securities Exchange Act of 1934 
applicable to it and shall comply with all other public information reporting 
requirements of the Commission which are conditions to the availability of 
Rule 144 for the sale of the Registrable Securities.  The Company shall 
cooperate with each Purchaser in supplying such information as may be 
necessary for such Purchaser to complete and file any information reporting 
forms presently or hereafter required by the Commission as a condition to the 
availability of Rule 144.

12.  Limitation on Registration.  The Company shall not be obligated to effect 
a registration of any Holder's Registrable Securities pursuant to Sections 2 
or 3 hereof if all of the Registrable Securities have  been sold under Rule 
144, Regulation S or similar provision under the Securities Act so that there 
is no further restriction on the transfer by the transferee.  The Company 
shall not be required to include any Registerable Securities of a Holder in a 
registration if all of such Holder's Registerable Securities could be sold 
within a three month period pursuant to Rule 144 or other similar rule or 
regulation.

13.  Miscellaneous.  (a) No Inconsistent Agreements.  The Company will not 
hereafter enter into any agreement with respect to its securities which is 
inconsistent with or violates the rights granted to the Holders of Registrable 
Securities in this Agreement.

(b) Remedies.  Any Person having rights under any provision of this Agreement  
will be entitled to enforce such rights specifically to recover damages caused 
by reason of any breach of any provision of this Agreement and to exercise all 
other rights granted by law.  The parties hereto agree and acknowledge that 
money damages may not be an adequate remedy for any breach of the provisions 
of this Agreement and that any party may in its sole discretion apply to any 
court of law or equity of competent jurisdiction (without posting any bond or 
other security) for specific performance and for other injunctive relief in 
order to enforce or prevent violation of the provisions of this Agreement; 
provided that in no event shall any Holder have the right to enjoin or 
interfere with any offering of securities by the Company.

(c) Amendments and Waivers.  Except as otherwise provided herein, the 
provisions of this Agreement may be amended or waived only upon the prior 
written consent of the Company and Holders of at least 50% of the Registrable 
Securities; provided, that without the prior written consent of all the 
Holders, no such amendment or waiver shall reduce the foregoing percentage.

(d) Successors and Assigns.  Subject to Section 9 hereof, all covenants and 
agreements in this Agreement by or on behalf of any of the parties hereto will 
bind and inure to the benefit of the respective  successors and assigns of the 
parties hereto whether so expressed or not.  In particular, no Holder of 
Registrable Securities shall transfer registered securities (or securities 
convertible into, exerciseable or exchangeable for Registrable Securities) 
other than pursuant to Rule 144 or sale pursuant to an effective registration 
statement, whether or not the transferee shall have rights under this 
Agreement, without obtaining an agreement from the transferee to be bound by 
the terms of this Agreement; and in addition, whether or not any express 
assignment has been made, the provisions of this Agreement which are for the 
benefit of Holders of Registrable Securities are also for the benefit of, and 
enforceable by, any subsequent holder of Registrable Securities.

(e) Severability.  Whenever possible, each provision of this Agreement will be 
interpreted in such manner as to be effective and valid under applicable law, 
but if any provision of this Agreement is held to be prohibited by or invalid 
under applicable law, such provision will be ineffective only to the extent of 
such prohibition or invalidity, without invalidating the remainder of this 
Agreement.

(f) Counterparts.  This Agreement may be executed simultaneously in two or 
more counterparts, any one of which need not contain the signatures of more 
than one party, but all such counterparts taken together will constitute one 
and the same Agreement.

(g) Descriptive Headings.  The descriptive headings of this Agreement are 
inserted for convenience only and do not constitute a part of this Agreement.

(h) Governing Law.  All questions concerning the construction, validity and 
interpretation of this Agreement and the exhibits and schedules hereto will be 
governed by the internal law, and not the law of conflicts, of New York.

(i) Notices.  All notices, demands or other communications to be given or 
delivered under or by reason of the provisions of this Agreement shall be in 
writing and shall be deemed to have been given when delivered personally to 
the recipient or by telecopy, one day after being sent to the recipient by 
reputable overnight courier service (charges prepaid) or three days after 
being mailed to the recipient by certified or registered mail, return receipt 
requested and postage prepaid.  Such notices, demands and other communications 
will be sent to the parties hereto at the addresses indicated on the signature 
page hereto and to the Company at the address indicated below:

Bioject Medical Technologies Inc.
7620 S.W. Bridgeport Road
Portland, Oregon 97224
Telecopier: 503-620-6431
Attention:  President

(j) Termination.  This Agreement shall terminate on the date as of which each 
Holder has sold all remaining Registrable Securities in a transaction or 
transactions of the type described in Section 12 hereof.


IN WITNESS WHEREOF, the parties have executed this Agreement as of the date 
first  written above.

Bioject Medical Technologies Inc.

By:/s/ James C. O'Shea
Name:  James C. O'Shea
Title: President

Elan International Services, Ltd.
By:/s/ Kevin Insley
Name:  Kevin Insley
Title: President and Chief Financial Officer



                                                               EXHIBIT 10.43

NEITHER THIS WARRANT NOR THE SHARES OF COMMON STOCK ISSUABLE UPON EXERCISE 
HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR 
ANY APPLICABLE STATE SECURITIES LAWS.  NO SALE OR DISPOSITION OF THIS WARRANT 
OR OF ANY SHARES OF COMMON STOCK ISSUED PURSUANT HERETO MAY BE EFFECTED 
WITHOUT (i) AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO, OR (ii) AN 
OPINION OF COUNSEL FOR THE HOLDER, REASONABLY SATISFACTORY IN FORM AND CONTENT 
TO THE COMPANY, THAT SUCH REGISTRATION IS NOT REQUIRED. 


                   BIOJECT MEDICAL TECHNOLOGIES INC.

                 SERIES "K" WARRANT TO PURCHASE SHARES
                            OF COMMON STOCK

THIS CERTIFIES THAT, for value received, Elan International Services, Ltd., a 
Bermuda corporation, or its affiliates or assigns or any other holder of this 
Warrant, as permitted herein (each, a "Holder"), is entitled to subscribe 
for and purchase up to 1,750,000 shares as adjusted pursuant to Section 4 
hereof(as so adjusted,  the "Shares") of the fully paid and nonassessable 
common stock without par value (the "Common Stock"), of Bioject Medical 
Technologies Inc., an Oregon corporation (the "Company"), at the price of 
$2.50 per share (such price, and such other price as shall result, from time 
to time, from the adjustments specified in Section 4 below, the "Warrant 
Price"), subject to the provisions and upon the terms and conditions 
hereinafter set forth.

1. Term.  The purchase right represented by this Warrant is exercisable, in 
whole or in part, at any time, and from time to time, from and after the date 
hereof and until 5:00 p.m. New York City Time October 15, 2002.  To the extent 
not exercised at 5:00 p.m. New York City Time on October 15, 2002, this 
Warrant shall completely and automatically terminate and expire, and 
thereafter it shall be of no force or effect whatsoever. 

2. Method of Exercise; Payment; Issuance of New Warrant. (a) The purchase 
right represented by this Warrant may be exercised by the Holder(s), in whole 
or in part and from time to time, by the surrender of this Warrant (with the 
notice of exercise form attached hereto as Annex A duly executed) at the 
principal office of the Company and by the payment to the Company of an 
amount, in cash or other immediately available funds, equal to the then 
applicable Warrant Price per Share multiplied by the number of Shares then 
being purchased.

(b)  The person or persons in whose name(s) any certificate(s) representing 
shares of Common Stock shall be issuable upon exercise of this Warrant shall 
be deemed to have become the holder(s) of record of, and shall be treated for 
all purposes as the record holder(s) of, the Shares represented thereby (and 
such Shares shall be deemed to have been issued) immediately prior to the 
close of business on the date or dates upon which this Warrant is exercised.  
Upon any exercise of the rights represented by this Warrant, certificates for 
the Shares purchased shall be delivered to the Holder(s) hereof as soon as 
possible and in any event within 10 business days of receipt of such notice 
and payment, and unless this Warrant has been fully exercised or expired, a 
new Warrant representing the portion of Shares, if any, with respect to which 
this Warrant shall not then have been exercised, shall also be issued to the 
holder hereof as soon as possible and in any event within such 30-day period.

3.  Stock Fully Paid, Reservation of Shares.  All Shares that may be issued 
upon the exercise of the rights represented by this Warrant will, upon 
issuance, be duly authorized, fully paid and nonassessable, and will be free 
from all taxes, liens and charges with respect to the issue thereof.  During 
the period within which the rights represented by this Warrant may be 
exercised, the Company will at all times have authorized, and reserved for the 
purpose of the issue upon the exercise of the purchase rights evidenced by 
this Warrant, a sufficient number of shares of its Common Stock to provide for 
the exercise of the rights represented by this Warrant.

4.  Adjustment of Warrant Price and Number of Shares.  The number and kind of 
securities purchasable upon the exercise of this Warrant and the Warrant Price 
shall be subject to the adjustment from time to time upon the occurrence of 
certain events, as follows:

(a)   Reclassification, Merger, Etc.  In case of (i) any reclassification, 
reorganization, change or conversion of securities of the class issuable upon 
exercise of this Warrant (other than a change in par value, or from par value 
to no par value), or (ii) any consolidation of  the Company with or into 
another corporation (other than a merger or consolidation with another 
corporation in which the Company is the acquiring and the surviving 
corporation and which does not result in any reclassification or change of 
outstanding securities issuable upon exercise of this Warrant), or (iii) any 
sale of all or substantially all of the assets of the Company, then the 
Company, or such successor or purchasing corporation, as the case may be, 
shall duly execute and deliver to the holder of this Warrant a new Warrant or 
a supplement hereto (in form and substance reasonably satisfactory to the 
holder of this Warrant), so that the holder of this Warrant shall have the 
right to receive, at a total purchase price not to exceed that payable upon 
the exercise of the unexercised portion of this Warrant, and in lieu of the 
shares of Common Stock theretofore issuable upon the exercise of this Warrant, 
the kind and amount of shares of stock, other securities, money and property 
receivable upon such reclassification, reorganization, change, conversion, 
merger or consolidation by a holder of the number of shares of Common Stock 
then purchasable under this Warrant.  Such new Warrant shall provide for 
adjustments that shall be as nearly equivalent as may be practicable to the 
adjustments provided for in this Section 4.  The provisions of this Section 
4(a) shall similarly attach to successive reclassifications, reorganizations, 
changes, mergers, consolidations and transfers.

(b)   Subdivision or Combination of Shares.  If the Company at any time during 
which this Warrant remains outstanding and unexpired shall subdivide or 
combine its Common Stock, (i) in the case of a subdivision, the Warrant Price 
shall be proportionately decreased and the number of Shares purchasable 
hereunder shall be proportionately increased, and (ii) in the case of a 
combination, the Warrant Price shall be proportionately increased and the 
number of Shares purchasable hereunder shall be proportionately decreased.

(c)   Stock Dividends; Etc.  If the Company at any time while this Warrant is 
outstanding and unexpired shall (i) pay a dividend with respect to Common 
Stock payable in Common Stock (or rights, options or warrants in respect 
thereof (collectively, "Options")), or (ii) issue any warrants, other than 
those currently outstanding or which the Company, prior to the date hereof has 
obligated itself to issue, or Options, other than up to 3,650,000 shares of 
Common Stock pursuant to a duly authorized and constituted stock option plan, 
to officers, directors, employees or consultants to the Company, having an 
exercise price (on a per-share basis) below the fair market value of a share 
of Common Stock on the date of authorization or grant of such Options, or 
(iii) make any other distribution with respect to Common Stock (except any 
distribution specifically provided for in Sections 4(a) and (b) above), the 
price at which the holder of this Warrant shall be able to purchase Shares 
shall be adjusted by multiplying the Warrant Price in effect immediately prior 
to such date of determination of the holders of securities entitled to receive 
such distribution, by a fraction (A) the numerator of which shall be the total 
number of shares of Common Stock outstanding immediately prior to such 
dividend or distribution, and (B) the denominator of which shall be the total 
number of shares of Common Stock outstanding immediately after such dividend 
or distribution, as if all of such Options had been exercised and the Company 
received the consideration payable in respect thereof.  Upon each adjustment 
in the Warrant Price pursuant to this Section  4(c), the number of Shares of 
Common Stock purchasable hereunder shall be adjusted, to the nearest whole 
share, to the product obtained by multiplying the number of Shares purchasable 
immediately prior to such adjustment in the Warrant Price by a fraction, the 
numerator of which shall be the Warrant Price immediately prior to such 
adjustment and the denominator of which shall be the Warrant Price immediately 
thereafter.

(d)   Repurchases or Redemptions of Common Stock or Options.  If the Company 
at any time while this Warrant is outstanding and unexpired shall repurchase 
or redeem any outstanding shares of Common Stock or any Options, other than 
its shares of Series C Preferred Stock, at a price which is greater than the 
then-current Market Price (for purposes hereof, Market Price shall be defined 
as the average closing price of the Common Stock for the 10 trading days 
ending on the day that is two business days prior to the date upon which the 
Company shall purchase or redeem any outstanding shares of Common Stock), the 
Warrant Price shall thereupon be adjusted by multiplying the Warrant Price in 
effect at the time of such repurchase by a fraction (i) the numerator of which 
shall be Warrant Price in effect immediately prior to such repurchase or 
redemption and (ii) the denominator of which shall be the fair market value of 
the consideration paid for the shares of Common Stock and/or Options at the 
time of purchase.  Upon each adjustment in the Warrant Price pursuant to this 
Section 4(d), the number of Shares of Common Stock purchasable hereunder shall 
be adjusted, to the nearest whole share, to the product obtained by 
multiplying the number of Shares purchasable immediately prior to such 
adjustment in the Warrant Price by a fraction, the numerator of which shall be 
the Warrant Price immediately prior to such adjustment and the denominator of 
which shall be the Warrant Price immediately thereafter.

(e)    No Impairment.  The Company will not, by amendment of its charter or 
bylaws or through any reorganization, recapitalization, transfer of assets, 
consolidation, merger, dissolution, issue or sale of securities or any other 
voluntary action, avoid or seek to avoid the observance or performance of any 
of the terms to be observed or performed hereunder by the Company, but will at 
all times in good faith assist in the carrying out of all the provisions of 
this Section 4 and in the taking of all such action as may be necessary or 
appropriate in order to protect the rights of the holder of this Warrant 
against impairment.

(f)    Notice of Adjustments.  Whenever the Warrant Price or the number of 
Shares purchasable hereunder shall be adjusted pursuant to this Section 4, the 
Company shall prepare a certificate setting forth, in reasonable detail, the 
event requiring the adjustment, the amount of the adjustment, the method by 
which such adjustment was calculated.  Such certificate shall be signed by its 
chief financial officer and shall be delivered to the holder of this Warrant.

(g)   Fractional Shares.  No fractional shares of Common Stock will be issued 
in connection with any exercise hereunder, but in lieu of such fractional 
shares the Company shall make a cash payment therefor based on the fair market 
value of the Common Stock on the date of exercise as reasonably determined in 
good faith by the Company's Board of Directors.

(h) Registration Requirement.  This Warrant may not be exercised by or for the 
account or benefit of any person other than Elan International Services, Ltd., 
or a transferee permitted hereunder, unless (i) the exercise transaction is 
covered by an effective registration statement under the Securities Act of 
1933, as amended (the "Act") and any applicable state securities laws; or 
(ii) registration under the Act, or any applicable state securities laws is 
not required, and the Company has received an opinion of counsel to such 
effect, in form and content satisfactory to the Company.

(i) Transferrability.   This Warrant shall be non-transferrable prior to 
February 1, 1998 and thereafter shall be transferrable only to (i) affiliates 
of the Holder or (ii) five non-affiliates thereof who are accredited 
institutions (as defined under Regulation D of the Securities Exchange Act of 
1934, as amended).

5.  Compliance with Securities Act; Disposition of Warrant or Shares of Common 
Stock.(a)  The holder of this Warrant, by acceptance hereof, agrees that this 
Warrant and the Shares to be issued upon exercise hereof are being acquired 
for investment and that such holder will not offer, sell or otherwise dispose 
of this Warrant or any Shares to be issued upon exercise hereof except under 
circumstances which will not result in a violation of applicable securities 
laws.  This Warrant and all Shares issued upon exercise of this Warrant 
(unless registered under the Act) shall be stamped or imprinted with a legend 
in substantially the following form:

"THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS 
AMENDED, OR ANY APPLICABLE STATE SECURITIES LAWS.  NO SALE OR DISPOSITION MAY 
BE EFFECTED WITHOUT (i) AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT AND 
APPLICABLE STATE SECURITIES LAWS RELATED THERETO OR (ii) AN OPINION OF COUNSEL 
FOR THE HOLDER, IN FORM AND CONTENT SATISFACTORY TO THE COMPANY, THAT SUCH 
REGISTRATION IS NOT REQUIRED. 

(b) With respect to any offer, sale or other disposition of this Warrant or 
any Shares acquired pursuant to the exercise of this Warrant prior to 
registration of such Shares, the holder hereof and each subsequent holder of 
this Warrant agrees to give written notice to the Company prior thereto, 
describing briefly the manner thereof, together with a written opinion of such 
holder's counsel in form and content satisfactory to the Company, if requested 
by the Company, to the effect that such offer, sale or other disposition may 
be effected without registration or qualification (under the Act as then in 
effect or any federal or state law then in effect) of this Warrant or such 
Shares and indicating whether or not under the Act certificates for this 
Warrant or such Shares to be sold or otherwise disposed of require any 
restrictive legend as to applicable restrictions on transferability in order 
to ensure compliance with the Act.  Promptly upon receiving such written 
notice and satisfactory opinion, if so requested, the Company, as promptly as 
practicable, shall notify such holder that such holder may sell or otherwise 
dispose of this Warrant or such Shares, all in accordance with the terms of 
the notice delivered to the Company.  Notwithstanding the foregoing, this 
Warrant or such Shares may be offered, sold or otherwise disposed of in 
accordance with Rule 144 as promulgated under the Act ("Rule 144"), provided 
that the Company shall have been furnished with such information as the 
Company may reasonably request to provide a reasonable assurance that the 
provisions of Rule 144 have been satisfied.  Each certificate representing 
this Warrant or the Shares thus transferred (except a transfer pursuant to 
Rule 144) shall bear a legend as to the applicable restrictions on 
transferability in order to insure compliance with the Act, unless in the  
aforesaid opinion of counsel for the holder, such legend is not required in 
order to insure compliance with the Act.  The Company may issue stop transfer 
instructions to its transfer agent in connection with such restrictions.

The shares issuable upon exercise of this Warrant are entitled to the benefit 
of certain registration rights as set forth in a Registration Rights Agreement 
dated as of the date hereof between the Company and the initial Holder named 
herein.

6.  Rights as Shareholders.  No holder of this Warrant, as such, shall be 
entitled to vote or receive dividends or be deemed the holder of Shares or any 
other securities of the Company which may at any time be issuable on the 
exercise hereof for any purpose, nor shall anything contained herein be 
construed to confer upon the holder of this Warrant, as such, any right to 
vote for the election of directors or upon any matter submitted to 
shareholders at any meeting thereof, or to receive notice of meetings, or to 
receive dividends or subscription rights or otherwise until this Warrant shall 
have been exercised and the Shares purchasable upon the exercise hereof shall 
have become deliverable, as provided herein.

7.  Representations and Warranties.  The Company represents and warrants to 
the holder of this Warrant as follows:

(a)  This Warrant has been duly authorized and executed by the Company and is 
a valid and binding obligation of the Company enforceable in accordance with 
its terms;

(b)  The Shares have been duly authorized and reserved for issuance by the 
Company and, when issued in accordance with the terms hereof, will be validly 
issued, fully paid and nonassessable; and

(c)  The execution and delivery of this Warrant are not, and the issuance of 
the Shares upon exercise of this Warrant in accordance with the terms hereof 
will not be, inconsistent with the Company's charter or bylaws, as amended, or 
by-laws, and do not and will not constitute a default under, any indenture, 
mortgage, contract or other instrument of which the Company is a party or by 
which it is bound.

8.  Miscellaneous.  (a) This Warrant and any provision hereof may be changed, 
waived, discharged or terminated only by an instrument in writing signed by 
both the Company and the holders of warrants that are outstanding at the time 
to purchase a majority of the shares of Common Stock issuable upon exercise of 
this Warrant remaining on the date of the action taken.

(b)  Any notice, request or other document required or permitted to be given 
or delivered to the holder hereof or the Company shall (i) be in writing, (ii) 
be delivered personally or sent by mail or overnight courier to the intended 
recipient to each such holder at its address as shown on the books of the 
Company or to the Company at the address indicated therefor on the signature 
page of this Warrant, unless the recipient has given notice of another 
address, and (iii) be effective on receipt if delivered personally, tw 
business days after dispatch if mailed, and one business day after dispatch if 
sent by overnight courier service.

(c)   Subject to the satisfaction of all of the provisions of this Warrant, 
the holder hereof may transfer all or any portion of this Warrant at any time 
to (i) an affiliate of the Holder initially namd herein and (ii) an aggregate 
of five non-affiliated institutions or investment vehicles, who are accredited 
investors (as that term is defined under Regulation D of the Securities Act of 
1933).

(d)  The Company covenants to the holder hereof that upon receipt of evidence 
reasonably satisfactory to the Company of the loss, theft, destruction, or 
mutilation of this Warrant and, in the case of any such loss, theft or 
destruction, upon receipt of a bond or indemnity reasonably satisfactory to 
the Company, or in the case of any such mutilation upon surrender and 
cancellation of such Warrant, the Company will make and deliver a new Warrant, 
of like tenor, in lieu of the lost, stolen, destroyed or mutilated Warrant.

(e)  The descriptive headings of the several sections and paragraphs of this 
Warrant are inserted for convenience only and do not constitute a part of this 
Warrant.

(f)  This Warrant shall be construed and enforced in accordance with, and the 
rights of the parties shall be governed by, the laws of the State of New York.


[Signature page follows]

IN WITNESS WHEREOF, Bioject Medical Technologies Inc. has executed this 
Warrant as of the date set forth below.

Bioject Medical Technologies Inc.


By:/s/ James C. O'Shea
Name:  James C. O'Shea
Title: President

Dated: October 15, 1997

 
                                                                  Annex A

NOTICE OF EXERCISE


To:  Bioject Medical Technologies Inc.


1.The undersigned hereby elects to purchase ____________ shares of Common 
Stock of Bioject Medical Technologies Inc. pursuant to the terms of the 
attached Warrant, and tenders herewith full payment of the purchase price of 
such shares, in cash or other immediately available funds.

2.Please issue a certificate or certificates representing said shares in the 
name of the undersigned or in such other name or names as are specified below:


                                                              
_____________________________________(Name)
                                                              

 (Address)                                           

3.The undersigned represents that the aforesaid shares are being acquired for 
the account of the undersigned for investment and not with a view to, or for 
resale in connection with, the distribution thereof and that the undersigned 
has no present intention of distributing or reselling such shares.

Signature:__________________________

Name:_____________________________

Address:___________________________

        ___________________________

        ___________________________

Social Security or taxpayer identification number:________________________




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