<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000810271
<NAME> Select Mid Cap Portfolio
<SERIES>
<NUMBER>009
<NAME>Smith Barney Investment Series
<S> <C>
<PERIOD-TYPE> Year
<FISCAL-YEAR-END> Oct-31-2001
<PERIOD-END> Oct-31-2000
<INVESTMENTS-AT-COST> 19,864,632
<INVESTMENTS-AT-VALUE> 21,003,103
<RECEIVABLES> 683,032
<ASSETS-OTHER> 334
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 21,686,469
<PAYABLE-FOR-SECURITIES> 212,561
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 54,748
<TOTAL-LIABILITIES> 267,309
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 20,163,357
<SHARES-COMMON-STOCK> 1,479,418
<SHARES-COMMON-PRIOR> 299,831
<ACCUMULATED-NII-CURRENT> 46,320
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 103,950
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,105,533
<NET-ASSETS> 21,419,160
<DIVIDEND-INCOME> 31,978
<INTEREST-INCOME> 78,528
<OTHER-INCOME> 0
<EXPENSES-NET> 62,757
<NET-INVESTMENT-INCOME> 47,749
<REALIZED-GAINS-CURRENT> 169,676
<APPREC-INCREASE-CURRENT> 1,011,621
<NET-CHANGE-FROM-OPS> 1,229,046
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 5,008
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 1,481,655
<NUMBER-OF-SHARES-REDEEMED> 302,494
<SHARES-REINVESTED> 426
<NET-CHANGE-IN-ASSETS> 18,387,510
<ACCUMULATED-NII-PRIOR> 3,579
<ACCUMULATED-GAINS-PRIOR> (65,726)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 49,370
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 142,546
<AVERAGE-NET-ASSETS> 6,614,539
<PER-SHARE-NAV-BEGIN> 10.110
<PER-SHARE-NII> 0.090
<PER-SHARE-GAIN-APPREC> 4.300
<PER-SHARE-DIVIDEND> 0.020
<PER-SHARE-DISTRIBUTIONS> 0.000
<RETURNS-OF-CAPITAL> 0.000
<PER-SHARE-NAV-END> 14.480
<EXPENSE-RATIO> 0.95
</TABLE>
