NEOPROBE CORP
10KSB/A, 1997-04-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                               ------------------

                                FORM 10-KSB/A1


For the fiscal year ended: December 31, 1996    Commission file number: 0-26520

                              NEOPROBE CORPORATION
- -------------------------------------------------------------------------------
                 (Name of Small Business Issuer in Its Charter)


               DELAWARE                                     31-1080091
   ----------------------------------              -----------------------
    (State or Other Jurisdiction of                     (I.R.S. Employer 
    Incorporation or Organization)                      Identification No.)

 425 Metro Place North, Suite 400, Dublin, Ohio             43017-1367
- ------------------------------------------------   -----------------------
  (Address of Principal Executive Offices)                 (Zip Code)

Issuer's Telephone Number, Including Area Code: (614) 793-7500

Securities registered under Section 12(b) of the Exchange Act: None

Securities registered under Section 12(g) of the Exchange Act:

                     Common Stock, par value $.001 per share
- -------------------------------------------------------------------------------
                                (Title of Class)

        Rights to Purchase Series A Junior Participating Preferred Stock
- -------------------------------------------------------------------------------
                                (Title of Class)

This Amendment Number 1 is being filed by the Registrant in order to refile its
financial statements with changes in the texts of Notes 7a, 9 and the last
paragraph of 11b.

The financial statements attached hereto supersede the financial statements for
the same fiscal periods attached to the Registrant's Form 10-KSB Annual Report
for the fiscal year ended December 31, 1996 filed on March 31, 1997 and 
Form 8-K Current Report filed on March 14, 1997.

<PAGE>   2


                                     PART IV

ITEM 13. EXHIBITS AND REPORTS ON FORM 8-K.

         (A) LIST OF EXHIBITS AND FINANCIAL STATEMENTS INCORPORATED BY REFERENCE

           (3)        ARTICLES OF INCORPORATION AND BY-LAWS

           3.1.       Complete Restated Certificate of Incorporation of Neoprobe
                      Corporation, as corrected February 18, 1994 and as amended
                      June 27, 1994, July 25, 1995 and June 3, 1996
                      (incorporated by reference to Exhibit 99.2 to the
                      Registrant's Current Report on Form 8-K dated June 20,
                      1996 (the "June 1996 Form 8-K"); Commission File No.
                      0-26520).

           3.2.       Amended and Restated By-Laws, dated July 21, 1993, as
                      amended July 18, 1995 and May 30, 1996 (incorporated by
                      reference to Exhibit 99.4 to the June 1996 Form 8-K).

           (4)        INSTRUMENTS DEFINING THE RIGHTS OF HOLDERS, INCLUDING
                      INDENTURES

           4.1.       See Articles FOUR, FIVE, SIX and SEVEN of the Restated
                      Certificate of Incorporation of the Registrant (see
                      Exhibit 3.1).

           4.2.       See Articles II and VI and Section 2 of Article III and
                      Section 4 of Article VII of the Amended and Restated
                      By-Laws of the Registrant (see Exhibit 3.2).

           4.3.       Rights Agreement dated as of July 18, 1995 between the
                      Registrant and Continental Stock Transfer & Trust Company
                      (incorporated by reference to Exhibit 1 to the
                      registration statement on Form 8-A, Commission File No.
                      0-26520).

           (10)       MATERIAL CONTRACTS (*indicates management contract or
                      compensatory plan or arrangement).

           10.1. 1.--10.1.18. Reserved

           10.1.19.   Form of Brokers' Warrants for the purchase of shares of
                      Common Stock dated February 17, 1995 issued to officers of
                      Sunrise Financial Corporation (incorporated by reference
                      to Exhibit 10.1.19 to the Registrant's Annual Report on
                      Form 10-KSB for the year ending December 31, 1994;
                      Commission File No. 0-26520 (the "1994 Form 10-KSB")).
                      This exhibit is one of six substantially identical
                      instruments and is accompanied by a schedule identifying
                      the other documents omitted and setting forth the material
                      details in which such documents differ from the one that
                      is filed therewith.

           10.1.20.   Reserved.

           10.1.21.   Participating Broker Agreement dated February 17, 1995
                      between Sunrise Securities Corp. and Registrant
                      (incorporated by reference to Exhibit 10.1.21 to the 1994
                      Form 10-KSB).

           10.1.22.   Reserved.

           10.1.23.   Brokers' Warrants for the purchase of shares of Common
                      Stock dated June 30, 1995 issued to officers of Sunrise
                      Financial Corporation (incorporated by reference to
                      Exhibit 10.1.23 to Registrant's Quarterly Report on Form
                      10-QSB for the quarter ending June 30, 1995; Commission
                      No. 0-26520 (the "2nd Quarter 1995 Form 10-QSB")). This
                      exhibit is one of six substantially identical instruments
                      and is accompanied by a schedule identifying the other
                      documents omitted and setting forth the material details
                      in which such documents differ from the one that is filed
                      therewith.

                                      -36-
<PAGE>   3

           10.1.24.   Participating Broker Agreement dated June 23, 1995 between
                      Sunrise Securities Corp. and Registrant (incorporated by
                      reference to Exhibit 10.1.24 to the 2nd Quarter 1995 Form
                      10-QSB).

           10.1.25.   Rights Agreement between the Registrant and Continental
                      Stock Transfer & Trust Company dated as of July 18, 1995
                      (see Exhibit 4.3).

           10.1.26.   Participating Broker Agreement dated September 8, 1995
                      between Registrant and Sunrise Securities Corp.
                      (incorporated by reference to Exhibit No. 1.3 to Amendment
                      No. 1 to registration statement on Form S-3; No.
                      33-96440).

           10.1.27.   Convertible Debenture issued by Neoprobe (Israel) Ltd. on
                      August 10, 1995 (incorporated by reference to Exhibit
                      10.1.27 to Registrant's Quarterly Report on Form 10-QSB
                      for the quarter ending September 30, 1995; Commission File
                      No. 0-26520 (the "3rd Quarter 1995 Form 10-QSB")). This
                      exhibit is one of three substantially identical
                      instruments and is accompanied by a schedule identifying
                      the other documents omitted and setting forth the material
                      details in which such documents differ from the one that
                      is filed therewith.

           10.1.28.   Letter agreement dated May 31, 1995 among Registrant, GKN
                      Securities Corp., David Nussbaum, Roger Gladstone, Robert
                      Gladstone and Ira Scott Greenspan (incorporated by
                      reference to Exhibit 99.1 to Registrant's Current Report
                      on Form 8-K dated May 31, 1995; Commission File No.
                      0-26520 (the "May 1995 Form 8-K")).

           10.1.29.   Form of Limited Recourse Promissory Note dated May 31,
                      1995 issued to Registrant (incorporated by reference to
                      Exhibit 99.2 to the May 1995 Form 8-K). This exhibit is
                      one of five substantially identical instruments and is
                      accompanied by a schedule identifying the other documents
                      omitted and setting forth the material details in which
                      such documents differ from the one that is filed
                      therewith.

           10.1.30.   Letter agreements dated March 13, 1995 and May 25, 1995
                      between Registrant and David Blech and D. Blech & Company
                      Incorporated (incorporated by reference to Exhibit 99.3 to
                      the May 1995 Form 8-K).

           10.2.1.--  10.2.14. Reserved.

           10.2.15.   Option Agreements between the Registrant and David C. Bupp
                      (incorporated by reference to Exhibit 10.7 to the
                      Registrant's registration statement on Form S-1; No.
                      33-51446 (the "Form S-1")).*

           10.2.16.-- 10.2.17. Reserved.

           10.2.18.   Non-Qualified Stock Option Agreement dated May 3, 1993
                      between the Registrant and David C. Bupp (incorporated by
                      reference to Exhibit 10.50 to the Registrant's Quarterly
                      Report on Form 10--QSB for the quarterly period ended June
                      30, 1993; Commission File No. 0-26520 (the "2nd Quarter
                      1993 Form 10-QSB")).*

           10.2.19.-- 10.20. Reserved.

           10.2.21.   Non-Qualified Stock Option Agreement dated May 3, 1993
                      between the Registrant and John L. Ridihalgh (incorporated
                      by reference to Exhibit 10.53 to the 2nd Quarter 1993 Form
                      10-QSB).*

           10.2.22.   Reserved.

                                      -37-
<PAGE>   4

           10.2.23.   Non-Qualified Stock Option Agreement dated February 28,
                      1992 and amended and restated June 3, 1993 between the
                      Registrant and David C. Bupp (incorporated by reference to
                      Exhibit 99.5 to Registrant's report on Form 8-K dated
                      January 21, 1994; Commission File No. 0-26520 (the
                      "January 1994 Form 8-K")).*

           10.2.24.   Non-Qualified Stock Option Agreement dated July 1, 1990
                      and amended and restated June 3, 1993 between the
                      Registrant and David C. Bupp (incorporated by reference to
                      Exhibit 99.6 to the January 1994 Form 8-K).*

           10.2.25.   Non-Qualified Stock Option Agreement dated June 1, 1992
                      and amended and restated June 3, 1993 between the
                      Registrant and John L. Ridihalgh (incorporated by
                      reference to Exhibit 99.7 to the January 1994 Form 8-K).*

           10.2.26.   Amended and Restated Stock Option and Restricted Stock
                      Purchase Plan dated March 3, 1994 (incorporated by
                      reference to Exhibit 10.2.26 to Registrant's annual report
                      on Form 10-KSB for the year ending December 31, 1993;
                      Commission File No. 0-26520 (the "1993 Form 10-KSB")).*

           10.2.27.   Letter agreement dated February 16, 1995 from the
                      Registrant to John L. Ridihalgh amending Employment
                      Agreement between them dated July 1, 1993 (incorporated by
                      reference to Exhibit 10.2.27 to the 1994 Form 10-KSB).*

           10.2.28.   Letter agreement dated February 16, 1995 from the
                      Registrant to David C. Bupp amending Employment Agreement
                      between them dated July 1, 1993 (incorporated by reference
                      to Exhibit 10.2.28 to the 1994 Form 10-KSB).*

           10.2.29.   Non-Qualified Stock Option Agreement dated February 16,
                      1995 between the Registrant and John L. Ridihalgh
                      (incorporated by reference to Exhibit 10.2.29 to the 1994
                      Form 10-KSB).*

           10.2.30.   Non-Qualified Stock Option Agreement dated February 16,
                      1995 between the Registrant and David C. Bupp
                      (incorporated by reference to Exhibit 10.2.30 to the 1994
                      Form 10-KSB).*

           10.2.31.   Employment Agreement dated as of January 1, 1996 between
                      the Registrant and John L. Ridihalgh (incorporated by
                      reference to Exhibit 10.2.31 to the Registrant's Quarterly
                      Report on Form 10-QSB for the quarterly period ended June
                      30, 1996; Commission File No. 0-26520 (the "2nd Quarter
                      1996 Form 10-QSB")).*

           10.2.32.   Employment Agreement dated as of January 1, 1996 between
                      the Registrant and David C. Bupp (incorporated by
                      reference to Exhibit 10.2.32 to the 2nd Quarter 1996 Form
                      10-QSB).*

           10.2.33    1996 Stock Incentive Plan (incorporated by reference to
                      Exhibit 10.2.33 to the 2nd Quarter 1996 Form 10-QSB).*

           10.2.34.   Restricted Stock Purchase Agreement dated June 5, 1996
                      between the Registrant and John L. Ridihalgh.* Previously 
                      Filed

           10.2.35.   Restricted Stock Purchase Agreement dated June 5, 1996
                      between the Registrant and David C. Bupp.*  Previously
                      Filed

           10.2.36.   Restricted Stock Purchase Agreement dated November 25,
                      1996 between the Registrant and Joseph R. Bianchine, as
                      amended January 2, 1997.*  Previously Filed

           10.3.1.    Technology Transfer Agreement dated July 29, 1992 between
                      the Registrant and The Dow Chemical Corporation
                      (incorporated by reference to Exhibit 10.10 to the Form
                      S-1, confidential 



                                      -38-
<PAGE>   5

                      portions of which were omitted and filed separately with
                      the Commission subject to an order granting confidential
                      treatment).

           10.3.2.--10.3.3. Reserved.

           10.3.4.    License Agreement dated August 15, 1992 between the
                      Registrant and Enzon, Inc. and Amendment thereto dated
                      August 19, 1992 (incorporated by reference to Exhibit
                      10.13 to the Form S--1).

           10.3.5.--10.3.6. Reserved.

           10.3.7.    Research and Development Agreement dated July 23, 1985,
                      among the Registrant, the Ohio State University and the
                      Director of Development of the State of Ohio, acting on
                      behalf of the State of Ohio (incorporated by reference to
                      Exhibit 10.16 to the Form S-1, confidential portions of
                      which were omitted and filed separately with the
                      Commission subject to an order granting confidential
                      treatment).

           10.3.8.    Supplemental Agreement dated July 19, 1985 between the
                      Registrant and The Ohio State University, acting on behalf
                      of the State of Ohio (incorporated by reference to Exhibit
                      10.17 to the Form S-1, confidential portions of which were
                      omitted and filed separately with the Commission subject
                      to an order granting confidential treatment).

           10.3.9.    Task Order Agreement for Sponsored Clinical Research dated
                      May 15, 1992, between the Registrant and The Ohio State
                      University Research Foundation (incorporated by reference
                      to Exhibit 10.18 to the Form S-1, confidential portions of
                      which were omitted and filed separately with the
                      Commission subject to an order granting confidential
                      treatment).

           10.3.10.   License Agreement dated July 23, 1992 between the
                      Registrant and The Ohio State University Research
                      Foundation (incorporated by reference to Exhibit 10.19 to
                      the Form S-1, confidential portions of which were omitted
                      and filed separately with the Commission subject to an
                      order granting confidential treatment).

           10.3.11.   License Agreement dated July 23, 1992 between the
                      Registrant and The Ohio State University Research
                      Foundation (incorporated by reference to Exhibit 10.20 to
                      the Form S-1, confidential portions of which were omitted
                      and filed separately with the Commission subject to an
                      order granting confidential treatment).

           10.3.12.--10.3.14. Reserved.

           10.3.15.   Option to License dated June 23, 1993 between the
                      Registrant, Biomeasure, Incorporated and Kinerton Limited
                      (incorporated by reference to Exhibit 10.54 to the 2nd
                      Quarter 1993 Form 10-QSB).

           10.3.16.   Drug Manufacture Agreement dated April 6, 1993 between the
                      Registrant and Nordion International Inc. (incorporated by
                      reference to Exhibit 10.55 to the 2nd Quarter 1993 Form
                      10-QSB, confidential portions of which were omitted and
                      filed separately with the Commission subject to an order
                      granting confidential treatment).

           10.3.17.   Sublicense Option Agreement dated May 15, 1993 between the
                      Registrant and NeoRx Corporation (incorporated by
                      reference to Exhibit 10.56 to the 2nd Quarter 1993 Form
                      10-QSB, confidential portions of which were omitted and
                      filed separately with the Commission subject to an order
                      granting confidential treatment).



                                      -39-
<PAGE>   6

           10.3.18.   Amendment I to License Agreement dated October 18, 1993
                      between the Registrant and Enzon, Inc. (incorporated by
                      reference to Exhibit 10.3.18 to Post-Effective Amendment
                      No. 2 to the Form S-1).

           10.3.19.--10.3.23. Reserved.

           10.3.24.   Amendment II to License Agreement dated March 11, 1994
                      between the Registrant and Enzon, Inc. (incorporated by
                      reference to Exhibit 10.3.24 to Registrant's Quarterly
                      Report on Form 10-QSB for the quarter ending March 31,
                      1994; Commission File No. 0-26520 (the "1st Quarter 1994
                      Form 10-QSB")).

           10.3.25.   License Agreement (Imaging Products License) dated August
                      1, 1994 between the Registrant and Biomeasure,
                      Incorporated (incorporated by reference to Exhibit 10.3.25
                      to registration statement on Form SB-2, No. 33-82278 (the
                      "Form SB-2"), confidential portions of which were omitted
                      and filed separately with the Commission subject to an
                      order granting confidential treatment).

           10.3.26.   License Agreement (Surgery Products License) dated August
                      1, 1994 between the Registrant and Biomeasure,
                      Incorporated (incorporated by reference to Exhibit 10.3.26
                      to the Form SB-2, confidential portions of which were
                      omitted and filed separately with the Commission subject
                      to an order granting confidential treatment).

           10.3.27.   Supply Agreement dated August 1, 1994 between Registrant
                      and Kinerton Limited (incorporated by reference to Exhibit
                      10.3.27 to the Form SB-2, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.3.28.   Reserved.

           10.3.29.   Manufacturing and Supply Agreement dated February 20, 1995
                      between the Registrant and Bio-Intermediair, B.V.
                      (incorporated by reference to Exhibit 10.3.29 to the 1994
                      Form 10-KSB).

           10.3.30.   Facility Agreement dated July 17, 1995 among Registrant,
                      Neoprobe (Israel) Ltd., and Rotem Industries, Ltd.
                      (incorporated by reference to Exhibit 10.3.30 to the 3rd
                      Quarter 1995 Form 10-QSB, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.3.31.   Cooperative Research and Development Agreement between
                      Registrant and National Cancer Institute (incorporated by
                      reference to Exhibit 10.3.31 to the 3rd Quarter 1995 Form
                      10-QSB).

           10.3.32.   First Amendment to Facility Agreement dated July 17, 1995
                      among Registrant, Neoprobe (Israel), Ltd. and Rotem
                      Industries, Ltd (incorporated by reference to Exhibit
                      10.3.32 to the Registrant's Annual Report on Form 10-KSB
                      for the year ending December 31, 1995; Commission File No.
                      0-26520 (the "1995 Form 10-KSB")).

           10.3.33.   Investment Agreement dated January 31, 1996 between the
                      Registrant and XTL Biopharmaceuticals, Ltd. (incorporated
                      by reference to Exhibit 10.3.33 to the Registrant's
                      Quarterly Report on Form 10-QSB for the quarterly period
                      ended March 31, 1996; Commission File No. 0-26520 (the
                      "1st Quarter 1996 Form 10-QSB")).

           10.3.34    $1,500,000 5% Convertible Subordinated Debenture Due
                      February 13, 1998 of XTL Biopharmaceuticals, Ltd. issued
                      to Registrant on February 13, 1996 (incorporated by
                      reference to Exhibit 10.3.34 to the 1st Quarter 1996 Form
                      10-QSB).

                                      -40-
<PAGE>   7

           10.3.35    Investors' Rights Agreement dated February 5, 1996 between
                      Registrant and XTL Biopharmaceuticals, Ltd. (incorporated
                      by reference to Exhibit 10.3.35 to the 1st Quarter 1996
                      Form 10-QSB).

           10.3.36    Warrant to purchase Class A Common Shares of XTL
                      Biopharmaceuticals, Ltd. issued to Registrant on February
                      13, 1996 (incorporated by reference to Exhibit 10.3.36 to
                      the 1st Quarter 1996 Form 10-QSB).

           10.3.37    Research and Development Agreement dated February 13, 1996
                      between Registrant and XTL Biopharmaceuticals, Ltd.
                      (incorporated by reference to Exhibit 10.3.37 to the 1st
                      Quarter 1996 Form 10-QSB, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.3.38    Sublicense Agreement dated February 13, 1996 between
                      Registrant and XTL Biopharmaceuticals, Ltd. (incorporated
                      by reference to Exhibit 10.3.38 to the 1st Quarter 1996
                      Form 10-QSB, confidential portions of which were omitted
                      and filed separately with the Commission subject to an
                      order granting confidential treatment).

           10.3.39    Limited Liability Company Agreement dated February 22,
                      1996 between Registrant and Peptor Corp. (incorporated by
                      reference to Exhibit 10.3.39 to the 1st Quarter 1996 Form
                      10-QSB).

           10.3.40    Subscription and Option Agreement dated March 14, 1996
                      between Registrant and Cira Technologies Inc.
                      (incorporated by reference to Exhibit 10.3.40 to the 1st
                      Quarter 1996 Form 10-QSB)

           10.3.41.   Reserved.

           10.3.42    Supply Agreement dated April 1, 1996 between
                      Neoprobe-Peptor JV L.L.C. and Peptor Ltd. (incorporated by
                      reference to Exhibit 10.3.42 to the 2nd Quarter 1996 Form
                      10-QSB, confidential portions of which were omitted and
                      filed separately with the Commission subject to an order
                      granting confidential treatment).

           10.3.43    Supply Agreement dated April 1, 1996 between
                      Neoprobe-Peptor JV L.L.C. and Neoprobe (Israel) Ltd.
                      (incorporated by reference to Exhibit 10.3.43 to the 2nd
                      Quarter 1996 Form 10-QSB, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.3.44    Technology Option Agreement dated as of March 14, 1996
                      between Cira Technologies, Inc. and Registrant
                      (incorporated by reference to Exhibit 10.3.44 to the 2nd
                      Quarter 1996 Form 10-QSB, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.3.45    License dated May 1, 1996 between Registrant and The Dow
                      Chemical Company (incorporated by reference to Exhibit
                      10.3.45 to the 2nd Quarter 1996 Form 10-QSB).

           10.3.46    License Agreement dated May 1, 1996 between Registrant and
                      The Dow Chemical Company (incorporated by reference to
                      Exhibit 10.3.46 to the 2nd Quarter 1996 Form 10-QSB,
                      confidential portions of which were omitted and filed
                      separately with the Commission subject to an order
                      granting confidential treatment).

           10.4.1.--10.4.15. Reserved.

                                      -41-
<PAGE>   8

           10.4.16.   Project Management Agreement dated May 17, 1995 between
                      Neoprobe (Israel) Ltd. and BARAN Project Construction Ltd.
                      (incorporated by reference to Exhibit 10.4.16 to the 2nd
                      Quarter 1995 Form 10-QSB).

           10.4.17.   Strategic Marketing Agreement dated August 30, 1995
                      between Registrant and Damon Pharm Ltd. (incorporated by
                      reference to Exhibit 10.4.17 to the 3rd Quarter 1995 Form
                      10-QSB, confidential portions of which were omitted and
                      filed separately with the Commission subject to an order
                      granting confidential treatment).

           10.4.18.   Exclusive Distribution Agreement dated September 25, 1995
                      between Registrant and Syncor International Corporation
                      (incorporated by reference to Exhibit 10.4.18 to the 3rd
                      Quarter 1995 Form 10-QSB, confidential portions of which
                      were omitted and filed separately with the Commission
                      subject to an order granting confidential treatment).

           10.4.19.   Exclusive Distribution Service Agreement dated November
                      30, 1995 between Registrant and Nordion Europe S.A.
                      (incorporated by reference to Exhibit 10.4.19 to the 1995
                      Form 10-KSB, confidential portions of which were omitted
                      and filed separately with the Commission subject to an
                      order granting confidential treatment).

           10.4.20.   License and Distribution Agreement dated September 18,
                      1996 between Registrant and United States Surgical
                      Corporation (incorporated by reference to Exhibit 10.4.20
                      to the Registrant's Quarterly Report on Form 10-QSB, as
                      amended by amendment no. 1 on Form 10-QSB/A, for the
                      quarter ended September 30, 1996; Commission File No.
                      0-26520, which was filed pursuant to Rule 24b-2 under
                      which the Registrant has requested confidential treatment
                      of certain portions of this Exhibit).

           (11)       STATEMENT REGARDING COMPUTATION OF PER SHARE EARNINGS.

           11.1.      Computation of Net Loss Per Share.  Previously Filed

           (21)       SUBSIDIARIES OF THE REGISTRANT.

           21.1.      Subsidiaries of the Registrant.  Previously Filed

           (23)       CONSENT OF EXPERTS AND COUNSEL.

           23.1       Consent of Coopers & Lybrand L.L.P.

           (24)       POWERS OF ATTORNEY.

           24.1.      Powers of Attorney. Previously Filed

           24.2.      Certified resolution of the Registrant's Board of
                      Directors authorizing officers and directors signing on
                      behalf of the Company to sign pursuant to a power of
                      attorney.  Previously Filed

     (B) REPORTS ON FORM 8-K.

         No current report on Form 8-K was filed by the Registrant during the
fourth quarter of fiscal 1995.



                                      -42-
<PAGE>   9


                                   SIGNATURES

     In accordance with Section 13 or 15(d) of the Securities Exchange Act of
1934, the Registrant has duly caused this amendment to be signed on its behalf 
by the undersigned, thereunto duly authorized.

Dated: April 11, 1997
                                                  NEOPROBE CORPORATION
                                                  (the "Registrant")


                                                  By: David C. Bupp
                                                  ---------------------------
                                                   David C. Bupp, President

     In accordance with the Exchange Act, this report has been signed below by
the following persons on behalf of the Registrant and in the capacities and on
the dates indicated.

<TABLE>
<CAPTION>

     SIGNATURE                                               TITLE                                      DATE

<S>                                                <C>                                             <C> 
John L. Ridihalgh*                                 Director, Chairman of the Board,                April 11, 1997
- -------------------------------------              Chief Executive Officer        
         John L. Ridihalgh                         (principal executive officer)  
                                                   

David C. Bupp                                      Director, President, Chief                      April 11, 1997
- -------------------------------------              Operating Officer and Treasurer     
           David C. Bupp                           (principal financial officer)       
                                                                                       
                                                   
John Schroepfer*                                   Vice President, Finance and                     April 11, 1997
- -------------------------------------
          John Schroepfer                          Administration

Jerry K. Mueller, Jr.*                             Director                                        April 11, 1997
- -------------------------------------
       Jerry K. Mueller, Jr.

James F. Zid*                                      Director                                        April 11, 1997
- -------------------------------------
            James F. Zid

Zwi Vromen*                                        Director                                        April 11, 1997
- -------------------------------------
             Zwi Vromen

Julius R. Krevans*                                 Director                                        April 11, 1997
- -------------------------------------
         Julius R. Krevans

Michael P. Moore*                                  Director                                        April 11, 1997
- -------------------------------------
          Michael P. Moore

J. Frank Whitley, Jr.*                             Director                                        April 11, 1997
- -------------------------------------
       J. Frank Whitley, Jr.

C. Michael Hazard*                                 Director                                        April 11, 1997
- -------------------------------------
         C. Michael Hazard

             *By:       David C. Bupp 
                   -------------------------------------------
                        David C. Bupp, Attorney-in-fact
</TABLE>


<PAGE>   10




- -------------------------------------------------------------------------------




                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549


                             -----------------------



                              NEOPROBE CORPORATION


                             -----------------------



                            FORM 10-KSB ANNUAL REPORT


                           FOR THE FISCAL YEAR ENDED:

                                DECEMBER 31, 1996



                             -----------------------

                               FINANCIAL STATEMENTS

                             -----------------------










===============================================================================


<PAGE>   11


REPORT OF INDEPENDENT ACCOUNTANTS

To the Directors and Stockholders of
Neoprobe Corporation

We have audited the accompanying consolidated balance sheets of Neoprobe
Corporation and Subsidiaries (A Development Stage Company) as of December 31,
1995 and 1996, and the related consolidated statements of operations,
stockholders' equity, and cash flows for the years ended December 31, 1994,
1995, and 1996, and for the period from November 16, 1983 (date of inception)
to December 31, 1996. These financial statements are the responsibility of the
Company's management. Our responsibility is to express an opinion on these
financial statements based on our audits.

We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of
material misstatement. An audit includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial statements. An audit
also includes assessing the accounting principles used and significant
estimates made by management, as well as evaluating the overall financial
statement presentation.  We believe that our audits provide a reasonable basis
for our opinion.

In our opinion, the financial statements referred to above present fairly, in
all material respects, the consolidated financial position of Neoprobe
Corporation and Subsidiaries (A Development Stage Company) as of December 31,
1995 and 1996, and the consolidated results of their operations and their cash
flows for the years ended December 31, 1994, 1995, and 1996, and for the period
from November 16, 1983 (date of inception) to December 31, 1996, in conformity
with generally accepted accounting principles.

                                                 Coopers & Lybrand L.L.P.

Columbus, Ohio
February 12, 1997


                                      F-1
<PAGE>   12


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED BALANCE SHEETS

December 31, 1995 and 1996

<TABLE>
<CAPTION>
                              ASSETS                                           1995                   1996
                                                                               ----                   ----
<S>                                                                        <C>                     <C>
Current assets:
     Cash and cash equivalents                                              $10,032,973            $30,168,412
     Available-for-sale securities                                            7,279,659             19,748,819
     Stock subscriptions receivable                                           1,262,513
     Accounts receivable                                                        184,330              1,240,474
     Inventory                                                                  473,004                216,272
     Prepaid expenses                                                           442,429              1,605,897
     Other current assets                                                       341,587                683,649
                                                                           ------------            -----------           
              Total current assets                                           20,016,495             53,663,523
                                                                           ------------            -----------           

Note receivable                                                                                      1,500,000
Property and equipment at cost:
     Equipment                                                                4,570,185              7,053,392
     Construction in progress                                                   262,026              1,226,966
                                                                           ------------            -----------           
                                                                              4,832,211              8,280,358

                  Less accumulated depreciation and amortization             (1,266,939)            (1,831,997)
                                                                           ------------            -----------           

                                                                              3,565,272              6,448,361
                                                                           ------------            -----------           
Intangible assets, net of accumulated amortization of $65,626 and
     $84,750, respectively                                                      523,249              2,130,335
Other assets                                                                     40,314                130,949
                                                                           ------------            -----------           
                  Total assets                                             $ 24,145,330            $63,873,168
                                                                           ============            ===========
</TABLE>


               The accompanying notes are an integral part of the
                       consolidated financial statements.

                                      F-2

<PAGE>   13


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED BALANCE SHEETS

<TABLE>
<CAPTION>
               LIABILITIES AND STOCKHOLDERS' EQUITY                                1995               1996
                                                                                   ----               ----
<S>                                                                           <C>                 <C>
Current liabilities:
     Accounts payable:
          Trade                                                                  $ 1,558,916       $ 2,368,357
          Related parties                                                             25,838            36,298
     Accrued expenses                                                                957,049         2,951,430
     Deferred revenue                                                                                2,000,000
     Notes payable to finance company                                                128,487           155,091
     Capital lease obligation, current                                               244,348            76,161
                                                                                 -----------      ------------

                  Total current liabilities                                        2,914,638         7,587,337
                                                                                 -----------      ------------

     Long-term debt                                                                1,100,000         1,000,687
     Capital lease obligation                                                         82,043             8,096
                                                                                 -----------      ------------
                  Total liabilities                                                4,096,681         8,596,120
                                                                                 -----------      ------------
Commitments and contingencies

Stockholders' equity:
     Preferred stock; $.001 par value; 5,000,000 shares authorized at December
         31, 1995 and 1996; none outstanding (500,000 shares designated as
         Series A, $.001 par value, at December 31, 1996; none outstanding)
     Common stock; $.001 par value; 50,000,000 shares authorized; 17,534,800
         shares issued and 17,334,800 shares outstanding at December 31, 1995;
         22,586,527 shares issued and outstanding at December 31, 1996                17,335            22,587
         Additional paid-in capital                                               62,964,787       119,293,862
         Deficit accumulated during development stage                            (43,146,860)      (64,116,003)
         Unrealized gain on available-for-sale securities                             46,480           (29,859)
         Cumulative foreign currency translation adjustment                          166,907           106,461
                                                                                 -----------      ------------
                  Total stockholders' equity                                      20,048,649        55,277,048
                                                                                 -----------      ------------

                  Total liabilities and stockholders' equity                     $24,145,330      $ 63,873,168
                                                                                 ===========      ============
</TABLE>


               The accompanying notes are an integral part of the
                       consolidated financial statements.

                                      F-3


<PAGE>   14


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED STATEMENTS OF OPERATIONS

<TABLE>
<CAPTION>
                                                                                                            November 16,
                                                                                                           1983 (Date of
                                                           Years Ended December 31,                        Inception) to
                                          -----------------------------------------------------------       December 31,
                                                1994                  1995                 1996                 1996        
                                          ------------------    -----------------     ---------------    -------------------
<S>                                       <C>                   <C>                    <C>                <C>
Net sales                                 $     933,056         $     959,984          $  1,171,186       $  4,058,997
Cost of goods sold                              587,972               505,998               676,773          2,128,297
                                            -----------           -----------          ------------       ------------

    Gross profit                                345,084               453,986               494,413          1,930,700
                                            -----------           -----------          ------------       ------------

Operating expenses:
  Research and development expenses:
    Wages and benefits                        2,444,922             3,152,741             5,694,484         14,865,442
    Contracted services                         348,544             1,646,309             4,709,492          9,246,939
    Clinical trials                           3,448,335             2,350,814             4,747,008         17,580,200
    Other                                       519,627               679,612               931,777          3,206,753
                                            -----------           -----------          ------------       ------------

    Total research and development            6,761,428             7,829,476            16,082,761         44,899,334
                                            -----------           -----------          ------------       ------------

  General and administrative expenses:
    Wages and benefits                          778,138             1,086,622             2,990,665          8,229,860
    Contracted services                         544,296               431,220               639,183          2,791,170
    Professional services                       896,961               455,234               616,441          3,329,532
    Depreciation and amortization               488,959               545,337               649,381          2,189,983
    Other                                     1,605,008             1,629,428             2,857,900          9,217,376
                                            -----------           -----------          ------------       ------------

    Total general and administrative          4,313,362             4,147,841             7,753,570         25,757,921
                                            -----------           -----------          ------------       ------------

Loss from operations                        (10,729,706)          (11,523,331)          (23,341,918)       (68,726,555)
                                            -----------           -----------          ------------       ------------

Other income (expense):
  Interest income                               180,771               603,275             2,179,345          3,765,385
  Interest expense                              (73,003)             (121,463)              (83,436)          (506,040)
  Gain (loss) on foreign currency
     transactions                                15,910                18,195               (43,459)           (44,663)
  Other                                         (15,318)              263,949               320,325          1,316,517
  Minority interest                              66,600                                                         79,353
                                            -----------           -----------          ------------       ------------


    Total other income                         174,960               763,956              2,372,775          4,610,552
                                            -----------           -----------          ------------       ------------

    Net loss                              $(10,554,746)         $(10,759,375)          $(20,969,143)      $(64,116,003)
                                          ============          ============           ============       ============

Loss per share data:
   Net loss per share of common stock     $      (1.18)                 (.73)                 (1.06)
                                          ============           ===========           ============

   Weighted-average number of shares
      outstanding during the year            8,926,196            14,725,687             19,743,649
                                          ============           ===========           ============
</TABLE>


               The accompanying notes are an integral part of the
                       consolidated financial statements.

                                      F-4


<PAGE>   15


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED STATEMENTS OF CASH FLOWS

<TABLE>
<CAPTION>
                                                                                                           November 16,
                                                                                                          1983 (Date of
                                                              Years Ended December 31,                    Inception) to
                                                 ----------------------------------------------------      December 31, 
                                                       1994               1995              1996               1996        
                                                 ---------------    ---------------    --------------    ---------------
<S>                                                <C>               <C>               <C>                <C>
Cash flows from operating activities:
  Net loss                                         $(10,554,746)      $(10,759,375)     $(20,969,143)      $(64,116,003)
  Adjustments to reconcile net loss to net
    cash used in operating activities:
    Depreciation and amortization                       495,838            551,992           652,623          2,208,318
    Loss on disposal of assets                           15,536              9,099            10,199             59,058
    Reissuance of treasury stock to 401(k) plan           2,034                                                  20,450
    Amortization of bond premium                         18,021                                                  18,021
    Minority interest                                   (66,600)                                                (79,353)
    Non-cash expenditures for research and
      development                                                                            500,000            500,000
    Compensation expense under restricted
      stock and stock option plans                                                         1,683,750          1,683,750
    Change in operating assets and liabilities:
      Accounts receivable                              (554,935)           396,725        (1,002,799)        (1,163,216)
      Inventory                                         202,578             64,757           248,734            211,705
      Prepaid expenses and other                         21,955           (252,076)         (566,291)        (1,235,679)
      Accounts payable                                  175,335             19,981           905,883          2,309,625
      Accrued expenses                                   81,825            740,579         1,996,641          2,922,209
      Deferred revenue                                                                     2,000,000          2,000,000      
                                                 ---------------    ---------------    --------------    ---------------

    Net cash used in operating activities           (10,163,159)        (9,228,318)      (14,540,403)       (54,661,115)
                                                 ---------------    ---------------    --------------    ---------------

Cash flows from investing activities:
  Purchases of available-for-sale securities         (4,030,743)       (16,564,908)      (50,061,144)       (94,673,416)
  Proceeds from sales of
    available-for-sale securities                     2,605,405          1,243,431        27,607,495         45,989,652
  Maturities of available-for-sale securities         2,965,000         10,763,965         9,982,000         28,964,742
  Purchases of property and equipment                  (525,519)        (1,434,524)       (3,616,297)        (6,518,917)
  Patents and organization costs                       (217,993)          (132,416)         (126,209)          (790,179)
  Other                                                                                          (78)           (48,980)
                                                 ---------------    ---------------    --------------    ---------------
    Net cash provided by (used in)
      investing activities                              796,150         (6,124,452)      (16,214,233)       (27,077,098)
                                                 ---------------    ---------------    --------------    ---------------

Cash flows from financing activities:
  Proceeds from notes payable                           169,761          1,243,696           180,242          3,271,822
  Proceeds from issuance of common stock, net         8,379,147         23,995,737        50,117,201        101,818,921
  Payment of notes payable                             (161,132)          (137,109)         (153,638)        (2,829,128)
  Proceeds under capital leases                         392,138                                                 481,545
  Payments under capital leases                        (171,721)          (212,199)         (241,390)          (646,149)
  Proceeds from issuance of preferred stock                                                                   8,845,879
  Treasury stock purchases                                                                                      (25,000)
  Proceeds from bank loan                                                                  1,000,687          1,000,687      
                                                 ---------------    ---------------    --------------    ---------------

    Net cash provided by financing                    8,608,193         24,890,125        50,903,102        111,918,577
      activities                                 ---------------    ---------------    --------------    ---------------

Effect of exchange rate changes on cash                   6,219             (5,157)          (13,027)           (11,952)
                                                 ---------------    ---------------    --------------    ---------------

    Net (decrease) increase in cash and
      cash equivalents                                 (752,597)         9,532,198        20,135,439         30,168,412

  Cash and cash equivalents, beginning of
    period                                            1,253,372            500,775        10,032,973                        
                                                 ---------------    ---------------    --------------    ---------------

   Cash and cash equivalents, end of period        $    500,775      $  10,032,973     $  30,168,412       $ 30,168,412
                                                 ===============    ===============    ==============    ===============
</TABLE>

               The accompanying notes are an integral part of the
                       consolidated financial statements.

                                      F-5


<PAGE>   16
NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY

<TABLE>
<CAPTION>
                                                                                                                            
                                                                                                               
                                                                                                                       Deficit
                                                                                                                     Accumulated    
                                              Common Stock                Preferred Stock            Additional      During the    
                                       --------------------------    ---------------------------      Paid-in        Development    
                                         Shares         Amount         Shares          Amount         Capital           Stage      
                                       -----------    -----------    -----------    ------------    ------------    ------------   
<S>                                    <C>            <C>            <C>            <C>            <C>              <C>            
Balance, November 16, 1983
  (inception):
  Sale of common stock
    ($.002-$7.84 per share),                            
    net of cost                         3,647,174      $   3,647                                   $  8,658,415
  Payment for stock purchase                                                                      
    option                                                                                               65,000 
  Issued at $6 per share for
    converting debt to equity              76,817             77                                        460,913                   
  Conversion of common stock
    to preferred stock                   (270,896)          (271)      541,792      $  2,123,824     (2,123,553)
  Sale of preferred stock at                                                                                             
    $4.12 per share                                                    484,849         2,000,002
  Repurchased shares at 
    $6 per share                           (4,166) 
  Reissued to 401(k) plan at                                                                   
    $6 per share                            3,830                                                        (4,550) 
  Conversion of preferred
    stock to common stock               1,715,205          1,715    (1,026,641)       (4,123,826)    10,967,988                   
  Issued to an employee for                         
    services                                1,750              2                                          6,998  
  Sale of common stock and
    warrants in connection
    with IPO (1,725,000            
    units at $6 per unit),
    net of costs                        1,725,000          1,725                                      8,177,959                   
  Issued to employees at par
    value                                  80,000             80                                                                  
  Exercise of employee stock
    options at $2 per share                 9,200              9                                         18,391                   
  Sale of common stock and
    warrants (550,000 units
    at $12 per unit), net of
    costs                               1,100,000          1,100                                      5,828,636
  Issued in connection with
    acquisition                           128,096            128                                        688,389                   
  Foreign currency                                                                                                          
    translation adjustment
  Net loss since inception
    to December 31, 1993                                                                                            $(21,832,739)  
                                       -----------    -----------    -----------    ------------    ------------    ------------   
</TABLE>

<TABLE>
<CAPTION>
                                                                            
                                                                          Unrealized
                                    Cumulative                            Gain (Loss)     
                                     Foreign                                  on              
                                    Currency                              Available-
                                    Translation         Treasury           for-Sale                                           
                                    Adjustment            Stock           Securities            Total    
                                   ------------        -----------        -----------        -------------   
<S>                                <C>                 <C>                <C>                <C>
Balance, November 16, 1983
  (inception):
  Sale of common stock
    ($.002-$7.84 per share),                                                                 
    net of cost                                                                              $   8,662,062
  Payment for stock purchase                                                                      
    option                                                                                          65,000    
  Issued at $6 per share for
    converting debt to equity                                                                      460,990
  Conversion of common stock
    to preferred stock             
  Sale of preferred stock at                                                                     2,000,002
    $4.12 per share
  Repurchased shares at 
    $6 per share                                       $  (25,000)                                 (25,000)
  Reissued to 401(k) plan at                             
    $6 per share                                           22,966                                   18,416
  Conversion of preferred
    stock to common stock                                                                        6,845,877
  Issued to an employee for                                                                          
    services                                                                                         7,000
  Sale of common stock and
    warrants in connection
    with IPO (1,725,000                                                                      
    units at $6 per unit),
    net of costs                                                                                 8,179,684
  Issued to employees at par                                                                          
    value                                                                                               80
  Exercise of employee stock
    options at $2 per share                                                                         18,400
  Sale of common stock and
    warrants (550,000 units
    at $12 per unit), net of                                                                   
    costs                                                                                        5,829,736
  Issued in connection with                                                                       
    acquisition                                                                                    688,517
  Foreign currency                              
    translation adjustment         $      5,790                                                      5,790
  Net loss since inception
    to December 31, 1993                                                                       (21,832,739)
                                   ------------        -----------        ----------            ----------- 
</TABLE>

CONTINUED


   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                      F-6
<PAGE>   17


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
<TABLE>
<CAPTION>
                                                                                                                            
                                                                                                               
                                                                                                                       Deficit
                                                                                                                     Accumulated    
                                              Common Stock                Preferred Stock            Additional      During the    
                                       --------------------------    ---------------------------      Paid-in        Development    
                                         Shares         Amount         Shares          Amount         Capital           Stage      
                                       -----------    -----------    -----------    ------------    ------------    ------------   
<S>                                    <C>            <C>            <C>            <C>             <C>              <C>            

Balance, December 31, 1993               8,212,010     $    8,212              0    $          0    $ 32,744,586    $(21,832,739) 

  Exercise of employee
    stock options at $2 per 
    share                                    2,000              2                                          3,998 
  Exercise of stock
    warrants ($3.75 to
    $4.50 per share)                        12,140             12                                         50,065 
  Issued in connection with
    acquisition                             76,967             77                                        480,967   
  Reissued to 401(k) plan
    at $6 per share                          1,398              1                                          6,575         
  Sale of common stock at
    $2.27 per share, net of
    costs                                2,000,000          2,000                                      4,426,825   
  Exercise of warrants for
    common stock at $.001
    per share in exchange
    for $550 (par value)
    and cancellation of    
    other warrants of
    offsetting value                       550,000            550    
  Foreign currency
    translation adjustment         
  Net loss                                                                                                           (10,554,746)
                                       -----------    -----------    -----------    ------------    ------------    ------------   

Balance, December 31, 1994              10,854,515         10,854              0               0      37,713,016     (32,387,485)

  Issued to 401(k) plan                      3,253              3                                         13,065  
  Exercise of stock
    warrants ($3.75 to   
    $6.00 per share)                       549,712            550                                      2,492,750  
  Exercise of employee
    stock options ($2 to           
    $6 per share)                           97,745             98                                        328,486
  Sale of common stock at
    $2.27 per share, net of       
    costs                                3,000,000          3,000                                      5,914,171 
  Exercise of unit purchase
    option by underwriter
    at $2.22 per share, net
    of costs                               450,000            450                                        994,073  
  Sale of common stock at
    $5.50 per share, net of
    costs                                1,650,000          1,650                                      8,287,902
  Sale of common stock at
    $10.50 per share, net
    of costs                               575,000            575                                      5,696,782 
  Issued in connection with
    investments by
    marketing partner
    ($9.03 to $15.97 per 
    share), net of costs                   154,575            155                                      1,524,542
  Foreign currency
    translation adjustment 
  Unrealized gain on
    available-for-sale 
    securities 
  Net loss                                                                                                           (10,759,375)
                                       -----------    -----------    -----------    ------------    ------------    ------------   

</TABLE>


<TABLE>
<CAPTION>
                                                                            
                                                                          Unrealized
                                    Cumulative                            Gain (Loss)     
                                     Foreign                                  on              
                                    Currency                              Available-
                                    Translation         Treasury           for-Sale                                           
                                    Adjustment            Stock           Securities            Total    
                                   ------------        -----------        -----------        -------------   
<S>                                <C>                 <C>                <C>                <C>
Balance, December 31, 1993         $      5,790        $    (2,034)                          $  10,923,815

  Exercise of employee
    stock options at $2 per         
    share                                                                                            4,000
  Exercise of stock
    warrants ($3.75 to                                                                              
    $4.50 per share)                                                                                50,077  
  Issued in connection with
    acquisition                                                                                    481,044
  Reissued to 401(k) plan
    at $6 per share                                          2,034                                   8,610
  Sale of common stock at
    $2.27 per share, net of                                                                      
    costs                                                                                        4,428,825 
  Exercise of warrants for
    common stock at $.001
    per share in exchange
    for $550 (par value)
    and cancellation of                                                                                
    other warrants of
    offsetting value                                                                                   550   
  Foreign currency
    translation adjustment               88,222                                                     88,222
  Net loss                                                                                     (10,554,746)
                                   ------------        -----------        -----------        -------------  

Balance, December 31, 1994               94,012                  0                               5,430,397

  Issued to 401(k) plan                                                                             13,068
  Exercise of stock
    warrants ($3.75 to                                                                           
    $6.00 per share)                                                                             2,493,300
  Exercise of employee
    stock options ($2 to                                                                           
    $6 per share)                                                                                  328,584  
  Sale of common stock at
    $2.27 per share, net of                                                                     
    costs                                                                                        5,917,171
  Exercise of unit purchase
    option by underwriter
    at $2.22 per share, net           
    of costs                                                                                       994,523   
  Sale of common stock at
    $5.50 per share, net of                                                                      
    costs                                                                                        8,289,552
  Sale of common stock at
    $10.50 per share, net                                                                        
    of costs                                                                                     5,697,357
  Issued in connection with
    investments by
    marketing partner
    ($9.03 to $15.97 per                                                                        
    share), net of costs                                                                         1,524,697
  Foreign currency
    translation adjustment               72,895                                                     72,895
  Unrealized gain on
    available-for-sale                                                                             
    securities                                                            $    46,480               46,480
  Net loss                                                                                     (10,759,375)
                                   ------------        -----------        -----------        -------------   
</TABLE>

CONTINUED

   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                      F-7


<PAGE>   18


NEOPROBE CORPORATION AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY

<TABLE>
<CAPTION>
                                                                                                                            
                                                                                                               
                                                                                                                       Deficit
                                                                                                                     Accumulated    
                                              Common Stock                Preferred Stock            Additional      During the    
                                       --------------------------    ---------------------------      Paid-in        Development    
                                         Shares         Amount         Shares          Amount         Capital           Stage      
                                       -----------    -----------    -----------    ------------    ------------    ------------   
<S>                                    <C>            <C>            <C>            <C>             <C>              <C>            
  Balance, December 31, 1995            17,334,800        $17,335              0    $          0    $ 62,964,787    $(43,146,860) 
  Exercise of employee
    stock options at $2 to                 
    $6 per share                           132,075            132                                        553,139  
  Exercise of stock
    warrants ($3.32 to 
    $12.60 per share)                    2,904,421          2,905                                     18,165,986 
  Issued to 401(k) plan 
    at $3.46                                 5,426              5                                         18,792
  Issued to employee in
    exchange for services                   10,000             10                                        121,240
  Sale of common stock at
    $18.50 per share, net  
    of costs                             1,750,000          1,750                                     30,190,777
  Issued in exchange for
    technology licenses at 
    $16.03 per share                       124,805            125                                      1,999,875
  Issued in exchange for
    note receivable and
    development activities          
    at $20.25 per share                    125,000            125                                      2,531,125
  Issued in conversion of
    debentures at $5.93 
    per share                              200,000            200                                      1,185,641
  Vesting of compensatory
    employee options                                                                                   1,562,500  
  Foreign currency
    translation adjustment        
  Unrealized loss on
    available-for-sale
    securities
  Net loss                                                                                                           (20,969,143)   
                                       -----------    -----------    -----------    ------------    ------------    ------------   

  Balance, December 31, 1996            22,586,527        $22,587              0    $          0    $119,293,862    $(64,116,003)
                                       ===========    ===========    ===========    ============    ============    ============   
</TABLE>

<TABLE>
<CAPTION>
                                                                          Unrealized
                                    Cumulative                            Gain (Loss)     
                                     Foreign                                  on              
                                    Currency                              Available-
                                    Translation         Treasury           for-Sale                                           
                                    Adjustment            Stock           Securities            Total    
                                   ------------        -----------        -----------         ------------   
<S>                                <C>                 <C>                <C>                 <C>
  Balance, December 31, 1995       $    166,907        $         0        $    46,480         $ 20,048,649
  Exercise of employee
    stock options at $2 to
    $6 per share                                                                                   553,271
  Exercise of stock
    warrants ($3.32 to 
    $12.60 per share)                                                                           18,168,891
  Issued to 401(k) plan            
    at $3.46                                                                                        18,797
  Issued to employee in
    exchange for services                                                                          121,250
  Sale of common stock at
    $18.50 per share, net     
    of costs                                                                                    30,192,527
  Issued in exchange for
    technology licenses at          
    $16.03 per share                                                                             2,000,000
  Issued in exchange for
    note receivable and
    development activities
    at $20.25 per share                                                                          2,531,250
  Issued in conversion of
    debentures at $5.93 
    per share                                                                                    1,185,841
  Vesting of compensatory
    employee options                                                                             1,562,500
  Foreign currency
    translation adjustment              (60,446)                                                   (60,446)
  Unrealized loss on
    available-for-sale                                                                             
    securities                                                                (76,339)             (76,339)
  Net loss                                                                                     (20,969,143)
                                   ------------        -----------        -----------         ------------   
  Balance, December 31, 1996       $    106,461        $         0        $   (29,859)        $ 55,277,048
                                   ============        ===========        ===========         ============   
</TABLE>


   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                      F-8


<PAGE>   19


                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

1. ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:

  a.  ORGANIZATION AND NATURE OF OPERATIONS: Neoprobe Corporation ("the
      Company"), a Delaware corporation, is a development stage enterprise
      engaged in the development and commercialization of technologies for the
      diagnosis and treatment of cancers. There can be no assurance that the
      Company will be able to commercialize its proposed products. No
      significant revenues will be derived from the commercial marketing of the
      Company's RIGS(R) products until after the necessary government approvals
      are obtained, the first of which is not expected until 1997 at the
      earliest. Expenses incurred have been primarily for research and
      development activities and administration, resulting in an accumulated
      deficit of approximately $64,000,000. The Company is dependent on the
      proceeds of its securities and other financing vehicles to continue the
      commercial development of its proposed products.

  b.  BASIS OF PRESENTATION: The consolidated financial statements of the
      Company include the accounts of the Company and its majority-owned
      subsidiaries. All significant intercompany accounts and transactions have
      been eliminated in consolidation.

  c.  FOREIGN CURRENCY TRANSLATION: In accordance with Statement of Financial
      Accounting Standards (SFAS) No. 52, Foreign Currency Translation, assets
      and liabilities denominated in foreign currencies are translated at
      current exchange rates in effect at the balance sheet dates, and revenues
      and expenses are translated at the average monthly exchange rate. The
      differences resulting from such translations, as compared to the equity
      of subsidiaries which is translated at historical rates, are included in
      cumulative foreign currency translation adjustments, a separate component
      of stockholders' equity.

  d.  CASH AND CASH EQUIVALENTS: For purposes of the statements of cash flows,
      cash and cash equivalents consist of demand deposits, money market funds,
      highly liquid debt instruments and certificates of deposit with original
      maturities of three months or less.

  e.  AVAILABLE-FOR-SALE SECURITIES: Information related to amortized cost and
      fair value of available-for-sale securities at December 31, 1995 and 1996
      is provided below:

<TABLE>
<CAPTION>
                                                                                 GROSS
                                                          AMORTIZED           UNREALIZED
                           1995                             COST                 GAINS              FAIR  VALUE
                           ----                           ---------           ----------            -----------
          <S>                                            <C>                   <C>                  <C>
          U.S. Treasury and U.S. Government              $1,958,822            $40,501              $1,999,323
          Corporate debt securities                       5,274,357              5,979               5,280,336
                                                         ----------            -------              ----------
                                                         $7,233,179            $46,480              $7,279,659
                                                         ==========            =======              ==========
</TABLE>


<TABLE>
<CAPTION>
                                                                                GROSS
                                                         AMORTIZED           UNREALIZED
                           1996                             COST               LOSSES                FAIR VALUE
                           ----                             ----               ------                ----------
          <S>                                          <C>                    <C>                 <C>
          U.S. Treasury and U.S. Government              $   891,851          $(16,026)             $   875,825
          Corporate debt securities                       18,886,827           (13,833)              18,872,994
                                                         -----------          --------              -----------
                                                         $19,778,678          $(29,859)             $19,748,819
                                                         ===========          ========              ===========
</TABLE>



                                      F-9


<PAGE>   20

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]

      The fair value of debt securities at December 31, 1996, by contractual
      maturity, are shown below. Expected maturities may differ from
      contractual maturities as, under an existing investment agreement, the
      Company has the ability and intent to hold all securities for short-term
      working capital purposes.

<TABLE>
<CAPTION>
                                                         AMORTIZED
                           1995                             COST             FAIR VALUE
                           ----                             ----             ----------
          <S>                                             <C>                <C>
          Due one year or less                            $4,928,134         $ 4,967,125
          Due after one year through five years            2,016,948           2,023,117
          Due after five years through ten years             288,097             289,417
                                                          ----------         -----------                                     
                                                          $7,233,179         $ 7,279,659
                                                          ==========         ===========
</TABLE>

<TABLE>
<CAPTION>
                                                         AMORTIZED
                           1996                             COST             FAIR VALUE
                           ----                             ----             ----------
          <S>                                            <C>                 <C>
          Due one year or less                           $15,483,515         $15,498,661
          Due after one year through five years            4,295,163           4,250,158
                                                         -----------         -----------
                                                         $19,778,678         $19,748,819
                                                         ===========         ===========
</TABLE>

  f.  INVENTORY: The components of inventory at December 31, 1995 and 1996, are
      as follows:

<TABLE>
<CAPTION>
                                                              1995                1996
                                                              ----                ----
          <S>                                              <C>                 <C>
          Materials and component parts                     $101,886            $ 51,264
          Work in process                                    107,786              94,389
          Finished goods                                     263,332              70,619
                                                            --------            --------
                                                            $473,004            $216,272
                                                            ========            ========
</TABLE>

      Materials and component parts are valued at the lower of moving average
      cost or market. Work in process and finished goods are valued at the
      lower of cost (first-in, first-out) or market.

  g.  PROPERTY AND EQUIPMENT: Depreciation is computed using the straight-line
      method over the estimated useful lives of the depreciable assets.
      Maintenance and repairs are charged to expense as incurred, while
      renewals and improvements are capitalized. Equipment includes $770,545
      and $571,563 of equipment under capital leases and accumulated
      amortization of $423,958 and $393,384 at December 31, 1995 and 1996,
      respectively.

  h.  INTANGIBLE ASSETS: Intangible assets consist primarily of the cost of
      patents and acquired technology licenses. Patent costs are amortized on a
      straight-line basis over the remaining lives of the patents. Patent
      application costs are deferred pending the outcome of patent
      applications.  Costs associated with unsuccessful patent applications and
      abandoned intellectual property are expensed when determined to be
      worthless. The Company evaluates the potential alternative uses of
      intangible assets, as well as the recoverability of the carrying values
      of intangible assets on a recurring basis.

  i.  SALES REVENUE: The Company has derived revenues from the sale of blood
      group serology products and from sales of its radiation detection
      instruments. These sale transactions are independent of the clinical
      testing agreements and are not contingent upon the completion or results
      of clinical testing. The Company recognizes sales revenue when the
      product is shipped.

  j.  RESEARCH AND DEVELOPMENT COSTS: All costs related to research and
      development are expensed as incurred.

                                      F-10

<PAGE>   21

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


  k.  INCOME TAXES: The Company accounts for income taxes in accordance with
      SFAS No. 109, Accounting for Income Taxes. Under SFAS No. 109, deferred
      tax assets and liabilities are recognized based on temporary differences
      between the financial statement and tax basis of assets and liabilities
      using current statutory tax rates. SFAS No. 109 also requires a valuation
      allowance against net deferred tax assets if, based on the available
      evidence, it is more likely than not that some or all of the deferred tax
      assets will not be realized.

  l.  USE OF ESTIMATES: The preparation of financial statements in conformity
      with generally accepted accounting principles requires management to make
      estimates and assumptions that affect the reported amounts of assets and
      liabilities and disclosure of contingent assets and liabilities at the
      date of the financial statements and the reported amounts of revenues and
      expenses during the reporting period. Actual results could differ from
      those estimates.

  m.  NET LOSS PER COMMON SHARE: Net loss per common share is based on the
      weighted average number of common shares outstanding during the year. The
      loss per share for all periods presented excludes the number of common
      shares issuable upon the conversion of convertible debentures, and the
      number of shares issuable upon exercise of outstanding stock options and
      warrants into the Company's common stock since such inclusion would be
      antidilutive.

  n.  RECLASSIFICATIONS: Certain amounts have been reclassified to conform
      with the 1996 presentation.

2. ACCOUNTS RECEIVABLE:

   Accounts receivable at December 31, 1995 and 1996 consist of the following:

<TABLE>
<CAPTION>
                                                              1995                1996
                                                              ----                ----
                            <S>                             <C>              <C>
                            Trade                           $176,434          $  856,682
                            Related Parties                    7,896              28,771
                            Other                                                355,021
                                                            --------          ----------
                                                            $184,330          $1,240,474
                                                            ========          ========== 
</TABLE>

3. NOTE RECEIVABLE:

   At December 31, 1996, note receivable represents a convertible debenture
   from XTL Biopharmaceuticals Ltd. held by the Company related to an
   Investment and Research & Development Agreement (Note 11). The debenture is
   due on February 13, 1998, bears interest at 5%, and is payable annually.

4. ACCRUED EXPENSES:

    Accrued expenses at December 31, 1995 and 1996 consist of the following:

<TABLE>
<CAPTION>
                                                              1995                1996
                                                              ----                ----
                           <S>                            <C>                <C>
                           Royalties                      $   27,524         $    46,628
                           Compensation                      440,417           1,223,160
                           Taxes                              64,470              36,712
                           Contracted Services &
                            Other                            424,638           1,644,930
                                                           ---------          ----------
                                                           $ 957,049          $2,951,430
                                                           =========          ==========
</TABLE>

5. LONG-TERM DEBT:

   In 1995, Neoprobe (Israel) Ltd. ("Neoprobe (Israel)"), a subsidiary of the
   Company, and the Company issued convertible debentures in the amount of
   $1,100,000 due February 10, 1997. During 1996, all of the debentures were
   converted into 200,000 shares of the Company's common stock.

                                      F-11

<PAGE>   22

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


   In 1994, Neoprobe (Israel) received notification from the state of Israel's
   Finance Committee that a financial program had been approved for the
   construction and operation of a radiolabeling facility by Neoprobe (Israel)
   near Dimona, Israel. The amount of the approved investment is currently
   approximately $4.8 million. Neoprobe (Israel) has submitted a request to
   increase the approved investment by approximately $3.5 million. Under the
   approved program, Neoprobe (Israel) is entitled to government grants and
   government loan guarantees equal to a percentage of the total loan taken for
   the construction and operation of the facility. Amounts received under the
   agreement are collateralized by certain property obtained through the use of
   proceeds received. As of December 31, 1996, Neoprobe (Israel) has received
   approximately $1 million and $173,000 in the form of loans and grants,
   respectively. Amounts received as loans bear interest at the LIBOR rate plus
   a specified percentage based on the exchange rate differential between the
   Israeli shekel and the U.S. dollar, or approximately 7% at December 31, 1996.
   Principal payments are due at various dates based on the date of each
   respective loan draw. Based on loan draws received to date, principal
   amounts of approximately $13,770, $202,460, $439,636, $236,342 and $108,479
   become due in 1998 through 2002.

6. INCOME TAXES:

   As of December 31, 1996, net deferred tax assets approximated $24.1 million
   related principally to net operating loss carryforwards of approximately
   $55.6 million available to offset future taxable income, if any, through
   2011 and tax credit carryforwards of approximately $1.9 million (principally
   research and development) available to reduce future income tax liability
   after utilization of tax loss carryforwards, if any, through 2011. Due to
   the uncertainty surrounding the realization of these favorable tax
   attributes in future tax returns, all of the net deferred tax assets have
   been fully offset by a valuation allowance.

   Under Section 382 of the Internal Revenue Code of 1986, as amended, the
   utilization of net operating loss carryforwards may be limited under the
   change in stock ownership rules of the Internal Revenue Code. As a result of
   ownership changes which occurred in September 1994 and March 1989, the
   Company's operating tax loss carryforwards and tax credit carryforwards are
   subject to these limitations.

7. EQUITY:

   a. COMMON STOCK:

      The Company's research and development activities and operating costs
      have been funded principally with cash generated from the issuance of
      common stock.  In April 1996, the Company completed the sale of 1,750,000
      shares of common stock at a price of $18.50 per share in a secondary
      offering. Gross proceeds from this offering were $32.4 million, and
      proceeds net of underwriting discounts were $30.5 million.

      In November 1992 and December 1993, the Company issued a total of
      2,330,000 Class E Redeemable Common Stock Purchase Warrants ("Class E
      Warrants"). The Class E Warrants were exercisable over a three-year
      period beginning November 10, 1993 and expiring on November 12, 1996.
      During 1996, the Company received proceeds from the exercise of Class E
      Warrants of approximately $15.0 million.

      During 1994, 1995 and 1996 total cash generated from public offerings and
      private placements of common stock is as follows:

<TABLE>
<CAPTION>
                                                                           1994            1995           1996
                                                                      -------------    ------------    ------------
      <S>                                                             <C>              <C>             <C>
      Public offerings, including exercise of warrants..............  $   4,478,902    $ 21,134,865    $ 47,988,930
      Private placements and exercise of options....................      3,900,245       2,860,872       2,128,271
                                                                      -------------    ------------    ------------
                                                                      $   8,379,147    $ 23,995,737    $ 50,117,201
                                                                      =============    ============    ============

</TABLE>


   b. STOCK OPTIONS:

      At December 31, 1996, the Company has two stock-based compensation plans
      which are described below. The Company applies APB Opinion No. 25 and
      related interpretations in accounting for its plans. Accordingly, no
      compensation cost has been recognized related to fixed options granted
      under the plans. The compensation cost that has been charged against
      income related to performance-based plans was $1.7 million for 1996. Had
      compensation cost for the Company's two stock-based compensation plans
      been determined based on the fair value at the grant dates for awards
      under those plans, consistent with FASB Statement No. 123, the Company's
      net loss per share would have been increased to the pro forma amounts
      indicated below:

                                      F-12

<PAGE>   23

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


<TABLE>
<CAPTION>
                                                                   1995               1996
                                                                   ----               ----
                       <S>                    <C>              <C>                <C>
                       Net Loss               As reported      $(10,759,375)      $(20,969,143)
                                              Pro forma        $(11,319,278)      $(22,017,227)

                       Loss per Share         As reported      $      (0.73)      $      (1.06)
                                              Pro Forma        $      (0.77)      $      (1.12)
</TABLE>

      Under the Amended and Restated Stock Option and Restricted Stock Purchase
      Plan (the "Amended Plan"), and under the 1996 Stock Incentive Plan (the
      "1996 Plan"), which was adopted by the Board of Directors on January 18,
      1996, the Company may grant incentive stock options, nonqualified stock
      options, and restricted stock awards to full-time employees, and
      nonqualified stock options and restricted awards may be granted to
      consultants and agents of the Company. Total shares authorized under each
      plan are 2 million shares and 1.5 million shares, respectively. Under
      both plans, the exercise price of each option equals the market price of
      the Company's stock on the date of the grant.

      Options granted under the Amended Plan generally vest on a monthly basis
      over two to four years. Options granted under the 1996 Plan generally
      vest on an annual basis over three years. However, approximately 400,000
      options and 50,000 options have been granted under the Amended Plan and
      the 1996 Plan, respectively, which vest based on the achievement of
      various Company goals such as execution of a strategic worldwide
      marketing agreement and obtaining regulatory approvals related to the
      Company's products. During 1996, the Company recorded approximately $1.6
      million in compensation expenses related to the achievement of these
      goals.

      Outstanding options under the plans, if not exercised, will generally
      expire ten years from their date of grant or on the date of an optionee's
      separation from employment with the Company, except for those options
      granted in conjunction with employment agreements, which will expire ten
      years from their date of grant or two years after cessation of the
      optionee's employment, whichever occurs first.

      The fair value of each option grant was estimated on the date of the
      grant using the Black-Scholes option-pricing model with the following
      assumptions for 1995 and 1996, respectively: average risk-free interest
      rates of 7.4% and 5.7%; expected average lives of three and four years;
      no dividend rate for either year; and volatility of 181% for both years.

      A summary of the status of the Company's stock option plans as of
      December 31, 1994, 1995, and 1996, and changes during the years ended on
      those dates is presented below:

<TABLE>
<CAPTION>
                                           1994                          1995                          1996            
                                 --------------------------    -------------------------     --------------------------
                                                 WEIGHTED                     WEIGHTED                       WEIGHTED
                                                 AVERAGE                      AVERAGE                         AVERAGE
                                                 EXERCISE                     EXERCISE                       EXERCISE
                                  OPTIONS         PRICE         OPTIONS        PRICE          OPTIONS          PRICE   
                                 -----------    -----------    ----------    -----------     -----------     ----------
          <S>                    <C>              <C>          <C>             <C>           <C>               <C>
          Outstanding at
            beginning of year     1,094,560        $2.95        1,211,300       $3.29         1,723,543         $ 2.93
            
          Granted                   142,500        $6.32          680,780       $2.64           457,700         $15.38
          Forfeited                 (23,760)       $6.00          (70,792)      $5.68           (47,030)        $ 6.92
          Exercised                  (2,000)       $2.00          (97,745)      $3.36          (132,075)        $ 4.19
                                  ---------                     ---------                     ---------                
          Outstanding at
            end of year           1,211,300        $3.29        1,723,543       $2.93         2,002,138         $ 5.60
                                  =========                     =========                     =========                
          Options exercisable
             at end of year         655,292                       931,762                     1,265,893
                                
</TABLE>


      Included in outstanding options as of December 31, 1996 are 351,333
      options exercisable at a weighted-average price of $4.53 per share which
      vest on the meeting of certain Company achievements.

                                      F-13

<PAGE>   24

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


      The following table summarizes information about the Company's stock
      options outstanding at December 31, 1996:

<TABLE>
<CAPTION>
                                              OPTIONS OUTSTANDING                          OPTIONS EXERCISABLE       
                                -------------------------------------------------    --------------------------------
                                                      WEIGHTED
                                    NUMBER             AVERAGE        WEIGHTED           NUMBER           WEIGHTED
                                OUTSTANDING AT        REMAINING        AVERAGE       EXERCISABLE AT        AVERAGE
              RANGE OF           DECEMBER 31,        CONTRACTUAL      EXERCISE        DECEMBER 31,        EXERCISE
           EXERCISE PRICES           1996               LIFE            PRICE             1996              PRICE    
          ------------------    ----------------     ------------    ------------    ----------------    ------------
          <S>                       <C>                <C>             <C>              <C>                <C>
          $2.00 to $3.88               772,959         7 Years         $ 2.60              439,081         $ 2.68
          $5.75 to $6.50               785,479         6 Years         $ 6.03              745,479         $ 6.03
          $12.25 to $17.75             443,700         9 Years         $15.47               81,333         $15.47
                                     ---------                                           ---------              

                                     2,002,138                                           1,265,893
                                     =========                                           =========              
</TABLE>

   c. STOCK WARRANTS:

      At December 31, 1996, there are approximately 160,000 warrants
      outstanding to purchase common stock of the Company. The warrants are
      exercisable at prices ranging from $3.00 to $17.92 per share with a
      weighted average exercise price per share of $4.96. The warrants expire
      on various dates from 1997 through 2000.

      During 1995, the Company issued 450,000 shares of common stock related to
      the conversion of a unit purchase option issued during 1992. In exchange,
      the Company received cash and promissory notes totaling $999,500. The
      promissory notes were collected during 1995.

      During 1996, the Company issued warrants to purchase 150,000 shares of
      common stock (which were exercised) related to a 1992 license agreement.

   d. COMMON STOCK RESERVED: Shares of authorized common stock have been
      reserved for the exercise of all options and warrants outstanding.

   e. STOCK SUBSCRIPTIONS RECEIVABLE: During 1996, the Company collected $1.3
      million related to subscriptions for common stock outstanding at December
      31, 1995.

8. SHAREHOLDER RIGHTS PLAN:

   During July 1995, the Company's Board of Directors adopted a Shareholder
   Rights Plan. Under the plan, one "Right" is to be distributed for each share
   of common stock held by shareholders on the close of business on August 28,
   1995. The Rights are exercisable only if a person and its affiliate
   commences a tender offer or exchange offer for 15% or more of the common
   stock, or if there is a public announcement that a person and its affiliate
   has acquired beneficial ownership of 15% or more of the common stock, and if
   the Company does not redeem the Rights during the specified redemption
   period. Initially, each Right, upon becoming exercisable, would entitle the
   holder to purchase from the Company one unit consisting of 1/100th of a
   share of Series A Junior Participating Preferred Stock at an exercise price
   of $35 (which is subject to adjustment). Once the Rights become exercisable,
   if any person, including its affiliate, acquires 15% or more of the common
   stock of the Company, each Right other than the Rights held by the acquiring
   person and its affiliate becomes a right to acquire common stock having a
   value equal to two times the exercise price of the Right. The Company is
   entitled to redeem the Rights for $0.01 per Right at any time prior to the
   expiration of the redemption period.  The Shareholder Rights Plan and the
   Rights will expire on August 28, 2005.

                                      F-14

<PAGE>   25

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


9. INTERNATIONAL OPERATIONS:

   The following information relates to (New)MonoCarb AB (Sweden) and Neoprobe
   (Israel), the Company's international subsidiaries: 

<TABLE>
<CAPTION>
                                                              1994                1995               1996 
                                                              ----                ----               ----
          <S>                                             <C>                 <C>               <C>
          Net sales                                       $  850,000          $  803,000        $   391,000
          Loss from operations                             1,060,000           1,680,000          3,558,000
          Identifiable assets                              1,230,000           3,290,000          5,500,000
</TABLE>

   For the year ended December 31, 1996, approximately $258,000 and $70,000     
   of net sales were concentrated between two customers. For the year ended
   December 31, 1995, approximately $446,000 and $250,000 of net sales were 
   concentrated between two customers. For the year ended December 31, 1994, 
   approximately $750,000 of net sales were concentrated with a single customer.

10. RELATED-PARTY TRANSACTIONS:

   A partner of a law firm which provides various legal services to the
   Company, including patent and trademark filings and prosecuting patent and
   trademark applications, is a director and officer of the Company. Fees
   related to services performed by this firm approximated $346,000, $201,000
   and $201,000 for the years ended December 31, 1994, 1995, and 1996,
   respectively, and $1,513,000 for the period November 16, 1983 (inception)
   through December 31, 1996. The Company owed this law firm approximately
   $13,000 and $12,500 at December 31, 1995 and 1996, respectively. Also see
   Note 11.

11. AGREEMENTS:

   a. RESEARCH AND DEVELOPMENT:

      Under a research and development agreement between the Company, The Ohio
      State University, and the Department of Development of the State of Ohio,
      the Company must pay the State of Ohio periodic royalties calculated as a
      percentage of net sales of products utilizing the results of the
      sponsored research, a sharing of proceeds received from the sale of
      technology, and a portion of the royalties collected from any license the
      Company may grant. The Company has an option to terminate its royalty
      obligation following completion of the research period by making a
      termination payment to the State of Ohio.

   b. LICENSE AND TECHNOLOGY AGREEMENTS:

      In July 1992, the Company entered into a revised agreement with The Dow
      Chemical Company (Dow) for an exclusive global commercial sublicense to a
      specific antibody for use in RIGS system products subject to the approval
      of the National Cancer Institute of the National Institutes of Health
      (NCI/NIH). The NCI/NIH approved the sublicense arrangement in 1993. The
      agreement provides that the Company will pay Dow royalties on RIGS
      surgical system antibody product revenues. In October 1995, the Company
      entered an exclusive worldwide license agreement with Dow for use of its
      iodination technology. Under this agreement, the Company must pay
      royalties to Dow on net sales of radiolabeled targeting agents produced
      with Dow's iodination technology. The license lasts through the life of
      any patent covering this process. An officer of Dow is a director of the
      Company.

      In April 1993, the Company entered into a long-term clinical and
      commercial supply agreement with Nordion International Inc. (Nordion) for
      the radiolabeling of the Company's monoclonal antibody for clinical
      trials and commercial sale after regulatory approval to market has been
      granted.  The agreement will remain in force for a minimum of three years
      after the Company is granted approval to market in the U.S. or Europe.
      The Company agreed to purchase certain quantities of the radiolabeled
      antibody throughout the term of the agreement at prices already set or to
      be determined based on current information at the time of commercial
      approval. The Company incurred costs of approximately $560,000, $350,000,
      and $1.3 million for the years ended December 31, 1994, 1995, and 1996,
      respectively, and $2.5 million since execution of the agreement
      through December 31, 1996. 


                                      F-15

<PAGE>   26

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


      In February 1995, the Company signed a manufacturing and supply agreement
      with Bio-Intermediair B.V. (Bio-Intermediair) for the manufacture of the
      CC49 monoclonal antibody. The agreement is for a minimum of three years
      after the Company is granted regulatory approval to market with automatic
      one-year extensions thereafter. The Company has incurred costs of
      approximately $510,000 and $700,000 for the years ended December 31, 1995
      and 1996, respectively, under this agreement.

      In July 1995, the Company entered into an agreement with Neoprobe
      (Israel) and Rotem Industries Ltd. (Rotem) which amended and superseded a
      similar agreement dated April 1994 for Rotem's assistance in the
      construction and operation of a radiolabeling facility for the Company's
      targeting agents.  In consideration for their assistance, Rotem received
      a 5% equity interest in Neoprobe (Israel) and a monthly retainer until
      the facility is complete. Once the radiolabeling facility is complete,
      Rotem will be paid a management fee based on the volume of production.
      Rotem has the option to acquire an additional 5% equity interest in
      Neoprobe (Israel) during the period from July 1, 1996 to June 30, 1998 at
      a purchase price to be determined later. If certain sales levels have not
      been met by the end of 1999, Rotem has the right to receive an additional
      4% equity interest.  Rotem is guaranteed a 5% equity interest in Neoprobe
      (Israel) until such time as the contributed equity investment by the
      Company exceeds $2 million and the expenditures on the facility exceed
      $8,000,000 or the annual units shipped exceed 50,000.

      In August 1995, the Company signed a Cooperative Research and Development
      Agreement (CRADA) with the National Cancer Institute to develop and use
      specific monoclonal antibodies in RIGS surgeries. The agreement calls for
      the Company to contribute $750,000 for expenditures over the five-year
      term of the CRADA. The Company incurred costs of $31,000 and $85,000 for
      the years ended December 31, 1995 and 1996, respectively, under this
      program.

      In February 1996, the Company and XTL Biopharmaceuticals Ltd. ("XTL")
      executed a series of agreements, including an Investment Agreement and a
      Research and Development Agreement whereby XTL will perform specific
      research activities using XTL's proprietary technology for the
      development of future products for the Company. The Company purchased
      $1.5 million of convertible debentures of XTL, convertible into
      approximately a 15% equity interest in XTL as of the date of purchase.
      The Company also acquired a warrant affording Neoprobe the option to
      purchase an additional 10% equity interest in XTL. Neoprobe issued
      125,000 shares of common stock to XTL in exchange for the convertible
      debentures, a three year warrant, and future (approximately $1 million) 
      product development activities.

      In March 1996, the Company executed a Subscription and Option Agreement
      with Cira Technologies, Inc.("Cira"), under which the Company received a
      10% equity interest in Cira and an option to increase its interest in
      Cira by 15%. The exercise price for the option shall be 15% of the fair
      market value of Cira's outstanding securities on the earlier of (a) the
      third anniversary date of the license agreement, or (b) the commencement
      of a pivotal clinical trial study. The option price is subject to a
      minimum of $1.95 million and a maximum of $4.5 million. The Company's
      Chairman is a director and shareholder of Cira. Additionally, a partner
      of a law firm, who is a director of the Company which provides various
      legal services to the Company, is a principal shareholder of Cira. The
      Company and Cira also entered into an agreement under which it will
      provide financial, clinical, and technical support to Cira for Cira to
      conduct a clinical study using Cira's technology, and the Company will
      have an option to acquire an exclusive global license for Cira's
      technology. The Company's financial commitment for this clinical study
      will not exceed $500,000, and the Company has the right to terminate the
      agreement upon review of interim results of the clinical study. The
      Company has incurred expenses of approximately $125,000 for the year
      ended December 31, 1996 under this agreement.

      In May 1996, the Company executed two license agreements with Dow,
      whereby the Company was granted an exclusive license to technology
      covered by patents held by Dow. In exchange, the Company issued Dow
      124,805 shares of common stock valued at $2 million. Dow would also
      receive a specified percentage of any sublicense revenue received related
      to licensed technology. In addition, the Company agreed to make lump sum
      payments to Dow following marketing approval of certain initial products
      and on the achievement of certain sales milestones by the Company. Dow
      would also be paid royalties based on future net sales by the Company.
      Approximately $1.5 million of the cost of the license agreements was
      recorded as an intangible asset representing assets with alternative
      future uses. Management believes that no significant impairment of the
      intangible assets associated with the license agreement has occurred.

                                      F-16

<PAGE>   27

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


      In September 1996, the Company executed a marketing license agreement
      (the "Agreement") with United States Surgical Corporation ("USSC") giving
      USSC exclusive sales and marketing rights (excluding Korea, Thailand,
      Taiwan, Malaysia, and Singapore) for the Company's RIGS surgical cancer
      detection products. USSC will also provide surgeon training and
      professional education worldwide for RIGS products. The initial term of
      the Agreement is for five years from the later date on which the Company
      receives U.S. or European regulatory approval, and is renewable for
      successive five-year periods. Upon execution of the Agreement, the
      Company received a $2 million payment which has been recorded as deferred
      revenue. If the Company does not receive FDA or European regulatory       
      approvals for the RIGS system within 24 months from the execution date,
      and if USSC terminates the Agreement during this period, the Company must
      refund the payment to USSC. In addition, USSC agreed to pay the Company
      an additional $3.5 million upon receiving notification of marketing
      approval in the U.S. and Europe. Under the Agreement, the Company will
      pay USSC a commission on all RIGS-related product sales. USSC will make
      payments to the Company based on commissions collected from RIGS product
      sales to fund research and development on future RIGS products. In
      addition, USSC will pay royalties to the Company for all sales of RIGS
      disposable cancer detection products.

   c. EMPLOYMENT:

      The Company has employment agreements through December 31, 1998 with two
      of its executive officers which provide for restricted stock purchase
      agreements. The agreements provide that the officers can purchase up to
      an aggregate of 80,000 shares of the Company's common stock at par value
      subject to vesting provisions. Vesting of the shares does not commence
      unless there is a change in control of the Company. The unvested portion
      of the restricted shares will be forfeited no later than June 4, 2006.
      The Company has not recognized any expense under the agreement due to the
      contingent nature of the vesting provision and the risk of forfeiture.

12. LEASES:

    The Company leases certain office and manufacturing equipment under capital
    leases which expire on various dates through 2000. In December 1996, the
    Company entered into a seventy-seven month lease agreement for office space,
    commencing January 1, 1997. In June 1996, the Company entered into a lease
    agreement for MonoCarb's manufacturing facility, which will terminate in
    May, 2004.

    The future minimum lease payments for the years ending December 31 are as
    follows:

<TABLE>
<CAPTION>
                                                                         CAPITAL          OPERATING
                                                                         LEASES            LEASES
                                                                         ------            ------
                            <S>                                         <C>             <C>
                            1997                                        $86,183           $689,138
                            1998                                          6,336            663,712
                            1999                                                           676,206
                            2000                                                           679,257
                            2001                                                           681,108
                                                                        -------         ----------
                                                                        $92,519         $3,389,421
                            Less amount representing interest             8,262
                                                                        -------
                            Present value of net minimum
                             lease payments                             $84,257
                                                                        =======
</TABLE>


                                      F-17

<PAGE>   28

          NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS - [CONTINUED]


    Total rental expense under operating leases was approximately $529,000,
    $492,000, and $621,000 for the years ended December 31, 1994, 1995, and
    1996, respectively, and $2,188,000 for the period November 16, 1983
    (inception) to December 31, 1996.

13. EMPLOYEE BENEFIT PLAN:

    The Company maintains an employee benefit plan under Section 401(k) of the
    Internal Revenue Code. The plan allows employees to make contributions and
    the Company may, but is not obligated to, match a portion of the employee's
    contribution with the Company's common stock, up to a defined maximum. The
    Company recorded expenses of $13,000, $18,700, and $19,500 related to common
    stock to be contributed to the plan in 1994, 1995, and 1996, respectively,
    and $71,400 for the period November 16, 1983 (inception) through December
    31, 1996.

14. SUPPLEMENTAL DISCLOSURE FOR STATEMENTS OF CASH FLOWS:

    The Company paid interest, net of amounts capitalized, aggregating $70,972,
    $37,182, and $35,917 for the years ended December 31, 1994, 1995, and 1996,
    respectively, and $367,403 for the period November 16, 1983 (inception)
    through December 31, 1996.

    During 1995, the Company completed a strategic marketing agreement related
    to certain Asian markets for an additional investment of $700,000, of which
    $200,013 was included in subscriptions receivable as of December 31, 1995.
    The Company also received subscription agreements with other parties for the
    exercise of 200,000 warrants for which $1,062,500 is recorded as
    subscriptions receivable at December 31, 1995.

    During 1996, the Company issued common stock valued at a total of $5.7
    million in exchange for license rights, convertible debentures, warrants,
    and product development activities. The Company also incurred capital lease
    obligations of approximately $146,000, and $29,000 in 1994 and 1995,
    respectively, to finance equipment.

15. CONTINGENCIES:

    The Company is subject to legal proceedings and claims which arise in the
    ordinary course of its business. In the opinion of management, the amount of
    ultimate liability with respect to these actions will not materially affect
    the financial position of the Company.

                                      F-18

<PAGE>   29




- -------------------------------------------------------------------------------




                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549


                             -----------------------



                              NEOPROBE CORPORATION


                             -----------------------



                            FORM 10-KSB ANNUAL REPORT


                           FOR THE FISCAL YEAR ENDED:

                                DECEMBER 31, 1996



                             -----------------------


                                    EXHIBITS

                             -----------------------










===============================================================================



<PAGE>   1

                                                              Exhibit 23.1


                       CONSENT OF INDEPENDENT ACCOUNTANTS


We consent to the incorporation by reference in the Registration Statements of 
Neoprobe Corporation and Subsidiaries (A Development Stage Company) as listed 
below of our report dated February 12, 1997, on our audits of the consolidated 
balance sheets of Neoprobe Corporation and Subsidiaries (A Development Stage 
Company) as of December 31, 1995 and 1996, and the related consolidated 
statements of operations, stockholders' equity, and cash flows for the years 
ended December 31, 1994, 1995 and 1996, and for the period from November 16, 
1983 (date of inception) to December 31, 1996, which report is included in this 
Annual Report on Form 10-KSB.


           Form S-3           File No. 33-72700  
           Form S-3           File No. 33-73622  
           Form SB-2          File No. 33-86000  
           Form S-3           File No. 33-93438
           Form S-3           File No. 33-93858
           Form S-3           File No. 333-15989  
           Form S-8           File No. 33-70074  
           Form S-8           File No. 33-81410  
           Form S-8           File No. 333-05143  


                                                COOPERS & LYBRAND L.L.P.

Columbus, Ohio
April 11, 1997


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