NEOPROBE CORP
DEF 14A, 1997-04-23
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1

                              NEOPROBE CORPORATION

                         ------------------------------

                       1997 ANNUAL MEETING OF STOCKHOLDERS


                            SCHEDULE 14A INFORMATION

                Proxy Statement Pursuant to Section 14(a) of the
                         Securities Exchange Act of 1934

Filed by the registrant |X| 
Filed by a party other than the registrant |_|
Check the appropriate box: 
|_| Preliminary proxy statement 
|X| Definitive proxy statement 
|_| Definitive additional materials 
|_| Soliciting material pursuant to Section 240.14a-11(c) or Section 240.14a-12

                              Neoprobe Corporation
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)

                                   Registrant
- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of filing fee (Check the appropriate box):
|X|   No Fee Required
|_|   Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.
      (1) Title of each class of securities to which transaction applies:

________________________________________________________________________________

      (2) Aggregate number of securities to which transaction applies:

________________________________________________________________________________

      (3) Per unit price or other underlying value of transaction computed
pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee
is calculated and state how it was determined):

________________________________________________________________________________

      (4) Proposed maximum aggregate value of transaction:

________________________________________________________________________________

      (5) Total fee paid:

________________________________________________________________________________

      |_| Fee paid previously with preliminary materials.

      |_| Check box if any part of the fee is offset as provided by Exchange Act
Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid
previously. Identify the previous filing by registration statement number, or
the Form or Schedule and the date of its filing.
- --------------------------------------------------------------------------------
      (1) Amount previously paid:
- --------------------------------------------------------------------------------
      (2) Form, schedule or registration statement no.:
- --------------------------------------------------------------------------------
      (3) Filing party:
- --------------------------------------------------------------------------------
      (4) Date filed:
- --------------------------------------------------------------------------------
<PAGE>   2

[LOGO] neoprobe
                       1997 ANNUAL MEETING OF STOCKHOLDERS

                                                                  April 23, 1997

Dear Stockholder:

      You are cordially invited to attend the 1997 Annual Meeting of
Stockholders of Neoprobe Corporation which will be held at 11:00 a.m., Eastern
Daylight Time, on May 29, 1997 at The Hyatt on Capitol Square, 75 East State
Street, Columbus, Ohio. The matters on the meeting agenda are described in the
Notice of 1997 Annual Meeting of Stockholders and Proxy Statement which
accompany this letter.

      We hope you will be able to attend the meeting, but whatever your plans,
we ask that you please complete, execute, and date the enclosed proxy card and
return it in the envelope provided so that your shares will be represented at
the meeting.

                                         Very truly yours,


                                         John L. Ridihalgh
                                         Chairman of the Board and
                                           Chief Executive Officer
<PAGE>   3

                              NEOPROBE CORPORATION

                  NOTICE OF 1997 ANNUAL MEETING OF STOCKHOLDERS

                             TO BE HELD MAY 29, 1997

To the Stockholders of
NEOPROBE CORPORATION:

      The Annual Meeting of the Stockholders of Neoprobe Corporation, a Delaware
corporation (the "Company"), will be held at The Hyatt on Capitol Square, 75
East State Street, Columbus, Ohio, on May 29, 1997 at 11:00 a.m., Eastern
Daylight Time, for the following purposes:

      1.    To elect three directors, each to serve for a term of three years or
            until their successors are duly elected and qualified;

      2.    To consider and vote upon a proposal to amend the 1996 Stock
            Incentive Plan; and

      3.    To transact such other business as may properly come before the
            meeting or any adjournment thereof.

      The Board of Directors has fixed the close of business on April 4, 1997 as
the record date for the determination of stockholders entitled to notice of and
to vote at the Annual Meeting and any adjournment thereof. A list of
stockholders will be available for examination by any stockholder at the Annual
Meeting and for a period of 10 days before the Annual Meeting at the executive
offices of the Company.

      Whether or not you plan to attend the Annual Meeting, please sign, date,
and return the enclosed proxy card in the envelope provided.

                                          By Order of the Board of Directors


                                          John L. Ridihalgh
                                          Chairman of the Board and
                                            Chief Executive Officer


Columbus, Ohio
April 23, 1997
<PAGE>   4

                              NEOPROBE CORPORATION

                       ----------------------------------

                       1997 ANNUAL MEETING OF STOCKHOLDERS

                                  May 29, 1997
                       ----------------------------------

                                 PROXY STATEMENT

                              Dated April 23, 1997
                       ----------------------------------

                               GENERAL INFORMATION

      Solicitation. This Proxy Statement is furnished to the stockholders of
Neoprobe Corporation, a Delaware corporation (the "Company"), in connection with
the solicitation by the Board of Directors of the Company (the "Board of
Directors") of proxies to be voted at the 1997 Annual Meeting of Stockholders of
the Company (the "Annual Meeting") to be held on May 29, 1997 and any
adjournment thereof. This Proxy Statement and the accompanying proxy card are
first being mailed to stockholders on or about April 23, 1997.

      Voting Rights. Stockholders of record at the close of business on April 4,
1997 are entitled to notice of and to vote at the Annual Meeting. As of that
date, there were 22,712,436 shares of Common Stock of the Company, par value
$.001 per share ("Common Stock"), outstanding. Each stockholder of record on
April 4, 1997 is entitled to one vote per share held with respect to all matters
which may be brought before the Annual Meeting.

      Authorization. All shares represented by properly executed proxies
received by the Company pursuant to this solicitation will be voted in
accordance with the stockholder's directions specified on the proxy card. If no
directions have been specified by marking the appropriate squares on the
accompanying proxy card, the shares represented by such proxy will be voted in
accordance with the recommendations of the Board of Directors, which are (1) FOR
the election of Melvin D. Booth, John S. Christie and J. Frank Whitley, Jr. as
directors, each to serve for a term of three years; AND (2) FOR the approval of
the proposal to amend the 1996 Stock Incentive Plan. The proxy will also be
voted at the discretion of the persons acting under the proxy to transact such
other business as may properly come before the Annual Meeting and any
adjournment thereof.

      Revocation. Any stockholder returning the accompanying proxy has the power
to revoke it at any time before its exercise by giving notice of revocation to
the Company, by duly executing and delivering to the Company a proxy card
bearing a later date, or by voting in person at the Annual Meeting.

      Tabulation. Under Section 216 of the General Corporation Law of the State
of Delaware ("GCL") and the By-laws of the Company, a quorum must be present at
the Annual Meeting in order for any valid action, including the election of
directors, the amendment of the 1996 Stock Incentive Plan (the "Original Plan")
and voting on the other matters presented to the meeting, other than
adjournment, to be taken thereat. Section 216 of the GCL and the By-laws of the
Company provide that a quorum consists of a majority of the shares entitled to
vote at the Annual Meeting present in person or represented by proxy. Shares
represented by signed proxies that are returned to the Company will be counted
toward the quorum in all matters even though they are marked as "Abstain,"
"Against" or "Withhold Authority" on one or more or all matters or they are not
marked at all (see "Authorization"). Broker/dealers, who hold their customers'
shares in street name, may, under the applicable rules of the exchanges and
other self-regulatory organizations of which such broker/dealers are members,
sign and submit proxies for such shares and may vote such shares on routine
matters,
<PAGE>   5

which, under such rules, typically include the election of directors, but
broker/dealers may not vote such shares on other matters without specific
instructions from the customer who owns such shares. Proxies signed and
submitted by broker/dealers which have not been voted on certain matters as
described in the previous sentence are referred to as broker non-votes. Such
proxies count toward the establishment of a quorum.

      Under Section 216 of the GCL and the By-laws of the Company, directors are
elected by a plurality of the votes for the respective nominees. Therefore,
proxies that are marked "Withhold Authority" and broker non-votes, if any, will
not affect the election of directors.

      Under Section 9.12 of the Original Plan, an amendment to the Original Plan
must be approved by the affirmative vote of the holders of a majority of the
shares of Common Stock present in person, or represented by proxy, and entitled
to vote at the Annual Meeting at which a quorum is present. A proxy marked
"Abstain" has the same effect as a vote against approval but a broker non-vote
is disregarded in determining the number of shares voted for approval and in
determining the total number of shares as to which the majority is determined in
such matter.

                              ELECTION OF DIRECTORS

Nominees for Election as Directors

      The Company presently has nine directors on its Board of Directors,
comprised of three directors in each of three classes, with terms expiring at
the Annual Meeting in 1997, 1998 and 1999, respectively. At the Annual Meeting,
the three nominees to the Board of Directors receiving the highest number of
votes will be elected as directors to a term of three years expiring in 2000.
Melvin D. Booth, John S. Christie and J. Frank Whitley, Jr. have been nominated
as directors to serve for a term of three years.

      The Company has no reason to believe that any of the nominees will not
stand for election or serve as a director. In the event any person nominated
fails to stand for election, the proxies will be voted for the election of such
other person as shall be designated by the persons named in the proxy. See
"General Information -- Tabulation."

      The Board of Directors has nominated the following persons to serve as
directors of the Company until the 2000 Annual Meeting:

      Melvin D. Booth, age 52, has been President, Chief Operating Officer and a
director of Human Genome Sciences, Inc. since July 1995. Mr. Booth was with
Syntex Corporation and its subsidiaries from 1975 to 1995. Mr. Booth was the
President of Syntex Laboratories, Inc. from 1993 to 1995 and served as a Vice
President of Syntex Corporation from 1992 to 1995. From 1992 to 1993 he served
as the President of Syntex Pharmaceuticals Pacific. From 1991 to 1992 he served
as an area Vice President of Syntex, Inc. From 1986 to 1991 he served as the
President of Syntex, Inc., Canada. He has been active in U.S. pharmaceutical
industry organizations and is also a past Chairman of the Pharmaceutical
Manufacturers Association of Canada. Mr. Booth has a B.S. degree from Northwest
Missouri State University and holds a Certified Public Accountant certificate.

      John S. Christie, age 47, has been President of JMAC, Inc., an investment
holding company, since September 1995. From August 1988 until September 1995, he
was a Senior Vice President of Battelle Memorial Institute. Mr. Christie also
serves as a director of Karrington Health, Inc. Mr. Christie has a B.S. degree
in Business Administration from Miami University and an MBA from Emory
University.

      J. Frank Whitley, Jr., age 54, has served as a director of the Company
since May 1994. Mr. Whitley has been Director of Mergers, Acquisitions and
Licensing at The Dow Chemical Company ("Dow"), a multinational chemical company,
since June 1993. Since joining Dow in 1965, Mr. Whitley has served in a variety
of marketing, financial, and business management functions. Mr. Whitley has a
B.S. degree in Mathematics from Lamar State University.


                                        2
<PAGE>   6

Directors Whose Terms Continue Until the 1998 Annual Meeting:

      David C. Bupp, age 47, has served as President, Chief Operating Officer
and a director of the Company since August 1992. From August 1992 to May 1993,
Mr. Bupp served as Treasurer of the Company. In addition to the foregoing
positions, from December 1991 to August 1992, he was Acting President, Executive
Vice President, Chief Operating Officer and Treasurer, and from December 1989 to
December 1991, he was Vice President--Finance and Chief Financial Officer. From
1982 to December 1989, Mr. Bupp was Senior Vice President, Regional Manager for
AmeriTrust Company National Association, a nationally chartered bank holding
company, where he was in charge of commercial banking operations throughout
Central Ohio. Mr. Bupp has a B.A. degree in Economics from Ohio Wesleyan
University. Mr. Bupp completed a course of study at Stonier Graduate School of
Banking.

      Julius R. Krevans, M.D., age 72, has served as a director of the Company
since May 1994. Dr. Krevans served as Chancellor of the University of
California, San Francisco from July 1982 until May 1993, and now serves on the
faculty of that institution's School of Medicine. Prior to his appointment as
Chancellor, Dr. Krevans served as a Professor of Medicine and Dean of the School
of Medicine at the University of California, San Francisco from 1971 to 1982.
Dr. Krevans is a member of the Institute of Medicine, National Academy of
Sciences, and led its committee for the National Research Agenda on Aging until
1991. He is Chairman of the Bay Area Economic Forum, a member of the Medical
Panel of A.P. Giannini Foundation, and a member of the Board of Directors of the
Bay Area BioScience Center. Dr. Krevans has a B.S. degree and an M.D. degree,
both from New York University.

      James F. Zid, age 63, has served as a director of the Company since
November 1993. Mr. Zid also serves as a director for the Net Med Corporation.
Now retired, Mr. Zid was a partner from September 1981 until September 1993 (and
served as managing partner of the Columbus, Ohio office from September 1981 to
September 1992) of Ernst & Young and its predecessors. Mr. Zid has a B.S. degree
in Accounting from St. Joseph's College.

Directors Whose Terms Continue Until the 1999 Annual Meeting:

      C. Michael Hazard, age 65, has served as a director of the Company since
May 1995. Mr. Hazard has been Chairman, Chief Executive Officer and a director
of Westfield Capital Management Company, an investment management firm, since
1989. Prior to founding Westfield Capital Management Company, he was Vice
Chairman and a director of Essex Investment Management Co., Inc. in Boston,
Massachusetts from 1977 to 1989. Mr. Hazard has a B.A. degree from Yale
University and is a graduate of the Wharton School Institute of Investment
Banking, University of Pennsylvania.

      Michael P. Moore, M.D., Ph.D., age 46, has served as a director of the
Company since May 1994. Dr. Moore has been Attending Physician, Breast Surgery,
Columbia Presbyterian Medical Center since June 1986. Dr. Moore has a B.S.
degree from Boston College, a Ph.D. degree from Loyola University of Chicago,
and an M.D. degree from The Loyola Stritch School of Medicine.

      John L. Ridihalgh, Ph.D., age 55, has served as a director of the Company
and Chairman of the Board since 1988. He was President of the Company from 1984
to November 1991. Dr. Ridihalgh served as Chief Executive Officer of the Company
from 1984 to November 1991 and resumed the position in June 1992. From November
1991 to June 1992, Dr. Ridihalgh served as a consultant to the Company. From
1968 to 1974, Dr. Ridihalgh was a research scientist at Battelle Memorial
Institute. He founded a consulting firm to the nuclear industry in 1974 and a
manufacturer of long-distance telephone network access devices in 1981. He is
also the founder of a medical instrument development company and an animal
vaccine company which has licensed a number of vaccines for veterinary use. Dr.
Ridihalgh has a B.S. degree in Mathematics and a Ph.D. degree in Nuclear
Engineering, both from Iowa State University.


                                        3
<PAGE>   7

Board of Directors Meetings

      The Board of Directors held six meetings in fiscal 1996 and each of the
directors attended at least 75 percent of the aggregate number of meetings of
the Board of Directors and committees (if any) on which he served.

Committees

      The Company has a standing Audit Committee and a standing Compensation
Committee. The Company does not have a committee whose functions include
nominating directors.

      The Audit Committee (comprised of James F. Zid (Chairman), J. Frank
Whitley, Jr. and C. Michael Hazard) recommends the firm to be employed by the
Company as its independent auditors; consults with the firm so chosen to be the
independent auditors with regard to the plan of audit; reviews, in consultation
with the independent auditors, their report of audit, or proposed report of
audit and the accompanying management letter, if any; and consults with the
independent auditors with regard to the adequacy of the internal accounting
controls. The Audit Committee held two meetings in fiscal 1996.

      The Compensation Committee (comprised of J. Frank Whitley, Jr. (Chairman),
Julius R. Krevans and James F. Zid) establishes the compensation of all
employees and consultants of the Company, administers and interprets the
Company's Amended and Restated Stock Option and Restricted Stock Purchase Plan
and the 1996 Stock Incentive Plan and takes any action that is permitted to be
taken by a committee of the Board of Directors under the terms of such plan,
including the granting of options. The Compensation Committee held two meetings
in fiscal 1996.

                   AMENDMENT TO THE 1996 STOCK INCENTIVE PLAN

Proposal

      The Original Plan was adopted by the Board of Directors on January 18,
1996 and approved by the Company's stockholders at the 1996 Annual Meeting of
Stockholders. The 1997 amendment to the 1996 Stock Incentive Plan (the "Amended
Plan") was adopted by the Board of Directors on March 13, 1997 and amends and
restates the Original Plan. The Board has proposed that the Company's
stockholders approve the Amended Plan. The material changes in the Original Plan
instituted by the Amended Plan are a provision allowing grants of limited
amounts of unrestricted stock to employees and consultants of the Company;
changing the number of shares subject to non-employee director annual stock
option awards ("Directors' Options") from 3,600 shares to 5,000 shares and
adding an attendance requirement to Board of Directors meetings as a
precondition to these grants; giving the Board of Directors power to increase or
decrease the number of shares covered by each Directors' Option; and removing
the limitation on the frequency with which the provisions concerning Director's
Options may be amended.

      The following is a description of the material features of the Amended
Plan. Material differences between the Amended Plan and the Original Plan are
specifically noted.

Purpose, Duration, Amendment and Termination

      The Amended Plan is designed to attract and retain capable directors,
employees and consultants and to provide them with long term incentives to
continue their services to the Company, to maximize the value of the Company to
its stockholders and to acquire a continuing ownership interest in the Company.
No award of unrestricted stock (an "Unrestricted Stock Award"), no award of a
stock option (an "Option") or award of a right to purchase restricted stock (a
"Restricted Stock Award") (collectively all Unrestricted Stock Awards, all
Options, and all Restricted Stock Awards are referred to as an "Award") may be
granted under the Amended Plan more than 10 years after January 18, 1996. The
Board of Directors may at any time terminate the Amended Plan, or make such
amendment to the Amended Plan as it may deem advisable. However, no amendment
will be effective without the approval of the stockholders of the


                                        4
<PAGE>   8

Company if it would materially increase the benefits accruing to participants
under the Amended Plan, materially increase the number of shares of Common Stock
which may be issued under the Amended Plan or materially modify the requirements
as to eligibility for participation in the Amended Plan. No amendment or
termination of the Amended Plan may alter or impair the rights of a person to
whom an Award was granted (a "Grantee") under any Award made before the adoption
of such amendment or termination by the Board of Directors, without the written
consent of such Grantee.

      The provisions of the Original Plan which provided that the formulae for
determining the exercise price of Directors' Options, the number of shares of
Common Stock as to which they are exercisable, the times when they are granted
and the persons who are participants could not be amended more than once every
six months, other than to comport with changes in the Internal Revenue Code of
1986 (the "Code") and the Employee Retirement Income Security Act of 1974, or
rules thereunder, are eliminated in the Amended Plan. These provisions in the
Original Plan were intended to comply with Securities and Exchange Commission
regulations which were rescinded in 1996.

Administration

      The Amended Plan will be administered by a committee of the Board of
Directors consisting of two or more directors, each of whom is a "non-employee
director" as defined in Rule 16b - 3(b)(3)(i) under the Securities Exchange Act
of 1934 and is an "outside director" as described in Section 162(m) of the Code
and the regulations thereunder (the "Committee"). Unless the Board of Directors
designates another of its committees to administer the Amended Plan, the Amended
Plan will be administered by a committee consisting of those members of the
Compensation Committee who are qualified, but, if the Compensation Committee is
abolished or its membership does not contain two persons who are qualified, the
Board of Directors will either reconstitute the Compensation Committee or create
another committee that complies with these requirements to administer the
Amended Plan. See "Election of Directors -- Committees." Subject to the express
provisions of the Amended Plan and in addition to the powers granted by other
sections of the Amended Plan, the Committee has the authority, in its
discretion, to determine the participants, grant Awards and determine their
timing, pricing and amount; define, prescribe, amend and rescind rules,
regulations, procedures, terms and conditions relating to the Amended Plan; make
all other determinations necessary or advisable for administering the Amended
Plan, including, but not limited to, interpreting the Amended Plan, correcting
defects, reconciling inconsistencies and resolving ambiguities; and review and
resolve all claims.

      The Original Plan required that the committee consist of two or more
directors, each of whom was a "disinterested person" as described in Rule 16b-3.
The term "disinterested person" was eliminated from Rule 16b-3 in 1996 and
replaced with the term "non-employee director" referenced above. The terminology
was changed in the Amended Plan to conform to the new terminology used in the
Rule.

Common Stock

      The aggregate number of shares of Common Stock in respect of which Awards
may be granted under the Amended Plan may not exceed 1,500,000. The Amended Plan
does not change this number. As of April 11, 1997, Awards had been granted with
respect to approximately 490,000 of these shares leaving approximately 1,010,000
shares in respect of which Awards may be granted under the Amended Plan. The
number of shares in respect of which Awards may be granted and the terms of any
Award will be adjusted proportionately if the shares of Common Stock are split,
combined or altered by a stock dividend or a merger or other corporate event. If
any Award granted under the Amended Plan is canceled, terminates or expires for
any reason without having been exercised in full, the shares of Common Stock
related to the unexercised portion of the Award may be used again. If any shares
of Common Stock purchased under the Amended Plan are forfeited for any reason,
the shares shall be available again for purposes of the Amended Plan. Except as
otherwise determined by the Board of Directors, the shares of Common Stock
issued under the Amended Plan will be authorized but unissued shares. However,
shares which are to be delivered under the Amended Plan may be obtained by the
Company from its treasury, by purchases on the open market or from private
sources. The proceeds of the exercise of any Award will be general corporate
funds of the Company.


                                        5
<PAGE>   9

Employees' and Consultants' Stock Options

      Only employees and consultants who are not members of the Committee
("Eligible Employees") are eligible to receive Options under this provision. On
December 31, 1996, the Company had 89 full-time employees and 16 consultants.
The Committee will determine which Eligible Employees will be granted Options,
the number of shares of Common Stock for which the Options may be exercised, the
times when they will receive them and the terms and conditions of individual
Option grants (which need not be identical); provided, however, that the maximum
number of shares of Common Stock with respect to which Options may be granted
during any fiscal year to any Eligible Employee will be 500,000. The Committee
will determine the exercise price of each Option at the time that it is granted,
but in no event will the exercise price of an Option be less than the fair
market value of a share of Common Stock on the date of grant, which is the
average closing price of the Common Stock on all securities exchanges on which
it is listed. On April 11, 1997, the closing price of a share of Common Stock on
the Nasdaq National Market was $14.25. The Committee has the authority, in its
discretion, to delegate to the officers of the Company the authority to select
Grantees (who are not officers) and grant Awards of Options to Eligible
Employees under this provision to such Grantees having terms and in aggregate
amounts determined by the Committee.

      The Committee will determine the term during which an Option is
exercisable at the time that it is granted, but no Option will be exercisable
after 10 years from the date of grant. Generally, each Option will vest and
first become exercisable as to one-third of the shares of Common Stock
originally subject to the Option on each anniversary of the date of grant
provided the Grantee thereof has been an employee or a consultant, as the case
may be, continuously during the time beginning on the date of grant and ending
on the date when such portion of the Option first becomes exercisable.
Generally, each Option will lapse and cease to be exercisable upon the earliest
of the expiration of 10 years from the date of grant, nine months after the
Grantee ceases to be an employee or consultant because of his death or
disability (six months for incentive stock options, see below), 90 days after
the Grantee's employment with or services to the Company are terminated by the
Company without cause, or immediately upon termination of the Grantee's
employment with or services to the Company for cause or by the Grantee's
resignation. The Committee may, in its sole discretion, accelerate the time at
which any Options become exercisable or waive any provisions of the Amended Plan
relating to the manner of payment or procedures for the exercise of any Option.
Any such acceleration may be made effective with respect to one or more or all
Grantees, with respect to some or all of the shares subject to an Option of any
Grantee or for a period of time ending at or before the expiration date of any
Option.

      The Committee will determine whether an Option is an incentive stock
option or a non-qualified option (as such terms are defined in the Code, see
"Taxation") at the time that it is granted, and if no express determination is
made by the Committee, all Options granted to employees who are not 10 percent
stockholders of the Company are incentive stock options and all Options granted
to consultants or 10 percent stockholders are non-qualified options. The
aggregate fair market value of the shares of Common Stock, determined as of the
time the Option is granted, which first become exercisable under all incentive
stock options granted to the Eligible Employee may not exceed $100,000 during
any calendar year and if that limit would be exceeded by the terms of any
incentive stock option, the exerciseability of a portion of such Option will be
deferred, but the Committee may, in its sole discretion, waive such deferral. No
10 percent stockholder will be granted an incentive stock option, unless the
exercise price thereof is at least 110 percent of the fair market value and the
Option is not exercisable after five years.

Directors' Stock Options

      Only a director who is not an employee of the Company and who has attended
at least 75 percent of the total number of meetings of the Board of Directors
(and committees thereof of which he is a member) during the most recently ended
fiscal year of the Company ("Eligible Director") is eligible to receive
Directors' Options under this provision. On the date the Amended Plan was
approved, each Eligible Director received a Directors' Option on 5,000 shares of
Common Stock. On the date of the first meeting of the Board of Directors in each
fiscal year of the Company ("First Meeting Date"), beginning in 1998, a
Directors' Option on 5,000 shares of Common Stock will be granted automatically
to each Eligible Director. The Board of Directors may, by a resolution adopted
on or before a First Meeting Date uniformly applying to all Eligible Directors,
increase or decrease the number of shares of Common Stock


                                        6
<PAGE>   10

subject to the Directors' Options granted on the First Meeting Date on which
such resolution is adopted and thereafter. The exercise price of such Directors'
Options will be the fair market value of a share of Common Stock on the date of
grant (see "Employees' and Consultants' Stock Options"). Under the Original
Plan, a director who was not an employee of the Company did not have to meet an
attendance requirement in order to be an Eligible Director, an Eligible Director
received an option for 3,600 shares of Common Stock each year and the Board of
Directors had no authority to increase or decrease the number of shares subject
to such options.

      Each Directors' Option shall vest and first become exercisable as to
one-third of the shares of Common Stock originally subject to the Directors'
Option on each First Meeting Date which occurs more than six months after the
date of grant if the Grantee is a director at the time of the adjournment of the
meeting of the Board of Directors held on such First Meeting Date. Each
Directors' Option shall lapse and cease to be exercisable upon the earlier of
the expiration of 10 years from the date of grant, nine months after the Grantee
ceases to be a director because of his death or disability, immediately upon
resignation by the director as a director, or 30 days after the director ceases
to be a director for any reason other than his death, disability or resignation.

      Directors' Options are non-qualified options (as such term is defined in
the Code), see "Taxation."

Restricted Stock Awards

      Only officers of the Company who are not members of the Committee
("Eligible Officers") are eligible to purchase Restricted Stock under the
Amended Plan. The Company had eleven Eligible Officers on April 4, 1997. The
Committee determines which Eligible Officers may purchase Restricted Stock, the
number of shares of Restricted Stock each Grantee may purchase, the times when
they may purchase Restricted Stock and the performance goals (see "Performance
Goals"), and the vesting and forfeiture provisions in the Restricted Stock
Purchase Agreement.

      Each Grantee must enter into a Restricted Stock Purchase Agreement under
which the Grantee purchases a number of shares of Restricted Stock for a
purchase price, which may be less than the market value of a share of Common
Stock but not less than the par value thereof ($.001 per share). A Holder may
not transfer or sell any shares of the Restricted Stock unless and until they
vest. Generally, the Holder will forfeit any portion of the Restricted Stock
that has not vested (and the Company will refund the purchase price paid) on the
earliest of nine months after the termination of employment by reason of death
or disability, 90 days after the termination of employment without cause,
immediately upon termination of employment for cause or if the Grantee resigns,
or on the expiration of the term of the Restricted Stock Purchase Agreement,
which may not be more than 10 years after the date of the Restricted Stock
Purchase Agreement. A portion of the Restricted Stock that has not previously
been forfeited shall vest and become transferable if and when the vesting
conditions established in the Restricted Stock Purchase Agreement are met. Such
conditions shall include a preestablished performance goal that satisfies the
requirements of Section 162(m) of the Code and the regulations thereunder. See
"Performance Goals." Except for these restrictions on transfer and possibilities
of forfeiture, the Holder has all other rights with respect to the Restricted
Stock, including the right to vote such shares or receive cash dividends.

Performance Goals

      The Committee will establish performance goals as preconditions to the
vesting of Restricted Stock Awards. Performance goals may be based on one or
more business criteria that apply to the individual Grantee, a business unit or
the Company as a whole. Such business criteria may include one or a combination
of stock price, total stockholder return, earnings per share or return on
equity. Other business criteria may be statistics relating to economic
performance including revenue, operating expenses, or earnings before interest,
taxes, depreciation and amortization; or the business criteria may be the
achievement of a non-statistical goal such as the introduction, testing or
licensing of a new product, licensing or acquiring assets or rights, entering
into a joint venture or strategic alliance, or a change in control of the
Company or another merger or acquisition.


                                        7
<PAGE>   11

Unrestricted Stock Awards

      An Unrestricted Stock Award is a grant of shares of Common Stock without
any precondition, restriction on transfer or risk of forfeiture. Only Eligible
Employees may receive Unrestricted Stock Awards under this provision. Under the
Amended Plan, the Committee may grant an Unrestricted Stock Award to an Eligible
Employee in consideration for services rendered by the Eligible Employee if such
services are deemed by the Committee to have a value to the Company in excess of
the par value of the shares so awarded. The Committee shall determine which
Eligible Employees will receive Unrestricted Stock, the number of shares of
Unrestricted Stock each grantee will receive, the times when each Grantee shall
receive Unrestricted Stock, and the terms and conditions of individual
Unrestricted Stock Awards (which need not be identical). The Committee may also
grant an Unrestricted Stock Award to a person to whom the Company is offering
employment, but any such grant shall lapse if the person does not subsequently
become an employee pursuant to such offer. The maximum number of shares of
Unrestricted Stock which may be granted during any fiscal year of the Company to
any one person shall be 25,000 shares. Promptly after the grant of an
Unrestricted Stock Award, the Company shall issue to the Grantee a certificate
representing the shares received thereunder. The Original Plan did not provide
for Unrestricted Stock Awards.

Provisions Applicable to all Types of Awards

      The Committee may, in its sole discretion, and upon such terms and
conditions as it shall determine at or after the date of grant, permit the
exercise price of an Award to be paid in cash, by the tender to the Company of
shares of Common Stock owned by the Grantee or by a combination thereof. If the
Committee does not make such determination, the exercise price must be paid in
cash, by certified or cashier's check, wire transfer or reduction of a debt of
the Company to the Grantee. Shares of Common Stock may not be delivered to the
Company as payment for the exercise of an Award, if such shares have been owned
by the Grantee (together with his decedent or testator) for less than six months
or if such shares were acquired upon the exercise of an incentive stock option
and their disposition would be taxable.

      The Committee may permit the voluntary surrender of all or a portion of
any Award to be conditioned upon the granting to the participant of a new Award
for the same or a different number of shares as the Award surrendered, or may
require such voluntary surrender as a condition precedent to a grant of a new
Award to such participant. Subject to the other provisions of the Amended Plan,
such new Award shall be exercisable at the price, during the period and on such
other terms and conditions as are specified by the Committee at the time the new
Award is granted. The Committee may grant Awards having terms and conditions
which vary from those specified in the Amended Plan if such Awards are granted
in substitution for, or in connection with the assumption of, existing awards
granted by another business entity and assumed or otherwise agreed to be
provided for by the Company pursuant to a transaction involving a merger or
consolidation of or acquisition of substantially all of the assets or stock of
another business entity that is not a subsidiary of the Company prior to such
acquisition. The Committee, subject to the written consent of the Grantee where
the action impairs or adversely alters the rights of the Grantee, has the right
at any time after the date of grant of any Award to modify its terms.

      Notwithstanding the terms of any Award, all Awards that have not
previously been exercised nor lapsed and ceased to be exercisable, will vest and
become exercisable upon the occurrence of any change in control of the Company
if the Grantee is then an employee, consultant or director, as the case may be.
A change in control includes (a) the acquisition, directly or indirectly, by a
person (other than the Company or an employee benefit plan established by the
Board of Directors) of beneficial ownership of 15 percent or more of the
Company's securities with voting power in the next meeting to elect the
directors; (b) the election of a majority of the directors elected at any
meeting of the holders of the Company's voting securities who are persons who
were not nominated by the Company's then current Board of Directors or
authorized committee thereof; or (c) the approval by the stockholders of the
Company of a merger or consolidation with another person, other than a merger or
consolidation in which the holders of the Company's voting securities continue
to hold voting securities in the surviving corporation (in the same relative
proportions as existed


                                        8
<PAGE>   12

before the event) comprising 80% percent or more of the voting power of the
surviving corporation; or (d) the approval by the stockholders of the Company of
a transfer of substantially all of the assets of the Company to another person
other than a transfer to a transferee, 80% percent or more of the voting power
of which is owned by the Company or by the holders of the Company's voting
securities in the same relative proportions to each other as existed before the
event.

Disability

      If a Grantee who is an employee with or consultant to the Company is
absent from work with the Company because of a physical or mental disability,
such Grantee will not be considered to have ended his employment with the
Company for purposes of the Amended Plan, while he has that disability, unless
he resigns or the Committee decides otherwise. If a Grantee who is a director is
absent from meetings of the Board of Directors because of a physical or mental
disability, such Grantee will not be considered to have ended his service with
the Board of Directors for purposes of the Amended Plan while the Grantee has
that disability, unless the Grantee resigns or is not re-elected by the
stockholders.

Transfer Restrictions

      No Award under the Amended Plan may be sold, pledged or otherwise
transferred other than by will or the laws of descent and distribution; and no
Award may be exercised during the life of the participant to whom it was granted
except by such participant.

Taxation

        GRANTEES SHOULD CONSULT WITH THEIR INDIVIDUAL TAX ADVISERS BEFORE
                EXERCISING ANY OPTION OR DISPOSING OF ANY SHARES
                      ACQUIRED ON THE EXERCISE OF AN AWARD

      Grantees are not taxed on the grant or exercise of an incentive stock
option. The difference between the exercise price of an incentive stock option
and the fair market value of a share of Common Stock received upon the exercise
of an incentive stock option may be subject to the federal alternative minimum
tax. If a Grantee exercises an incentive stock option and disposes of any of the
shares of Common Stock received by such Grantee as a result of such exercise
within two years from the date of grant or within one year after the transfer of
such shares to such Grantee, the Company will receive a tax deduction and the
Grantee will be taxed, as ordinary income, on the lesser of the gain on sale or
the difference between the exercise price and the fair market value of a share
at the time of exercise; and the Grantee must pay or provide for the withholding
taxes on such ordinary income. The Grantee will also have a capital gain to the
extent that the sale price exceeds the fair market value on the date of
exercise. If the shares are not sold by the Grantee before the end of those
periods, the Grantee will have a capital gain or capital loss upon sale of the
shares to the extent that the sale price differs from the exercise price. No tax
effect will result to the Company by reason of the grant or exercise of
incentive stock options, or upon the disposition of shares after expiration of
two years from the date of grant or one year from the date of exercise.

      Non-qualified options are not taxed upon grant. The Grantee is taxed, as
ordinary income, on the exercise of such an Option. The exercise of a
non-qualified option requires the Grantee to realize ordinary income to the
extent that the fair market value on the date of exercise exceeds the exercise
price. The Grantee's basis for determining capital gain or capital loss upon
sale of the shares is the higher of their fair market value on the date of
exercise and the exercise price. The Company is entitled to a deduction equal to
the ordinary income realized by the Grantee upon the exercise of non-qualified
options.

      Shares of Restricted Stock are not taxed upon purchase. The Holder will be
taxed, as having received ordinary compensation income, on the vesting of shares
of Restricted Stock. Such vesting requires the Holder to realize ordinary income
to the extent that the fair market value of the vested shares exceeds the amount
paid for such shares. The Holder's basis for determining capital gain or capital
loss upon the sale or exchange of vested shares of Restricted Stock


                                        9
<PAGE>   13

is the higher of the fair market value of shares on the date of vesting or the
purchase price thereof. The Company will be entitled to a deduction equal to the
ordinary income realized by the Holder upon the vesting of shares of Restricted
Stock.

      Upon the grant of shares of Unrestricted Stock, the Grantee will be taxed
as having received ordinary compensation income to the extent of the fair market
value of the shares of Unrestricted Stock. The Grantee's basis for determining
capital gain or capital loss upon the sale or exchange of shares of Unrestricted
Stock is the fair market value of shares on the date of grant. The Company will
be entitled to a deduction equal to the ordinary income realized by the Grantee
upon the grant of shares of Unrestricted Stock.

      The Amended Plan is intended to be a performance based compensation plan
that will comply with the requirements of Section 162(m) of the Code and the
regulations thereunder. If the Amended Plan complies with such law and
regulations and the Amended Plan continues to be in compliance, amounts
deductible by the Company under the Amended Plan will not be limited by the cap
on the deductibility of compensation paid to certain executive officers of
public corporations which exceeds $1,000,000. Because Section 162(m) is a new
provision of the Code, and compliance may depend upon factors, such as
relationships between the Company and the members of the Compensation Committee
and periodic re-authorization of the Amended Plan by the stockholders, which are
presently unforeseeable, no assurance can be given that the Company will remain
in compliance with these rules or that non-compliance will not cause amounts
payable under the Amended Plan to become non-deductible.


                                       10
<PAGE>   14

New Plan Benefits

      The following table sets forth the number of shares of Common Stock that
will be received under the Amended Plan by (i) each of the Named Executives (see
"Compensation of Management--Summary Compensation Table"), (ii) the current
executive officers of the Company as a group, (iii) the current directors of the
Company who are not executive officers, as a group, and (iv) all employees of
the Company, including all current officers of the Company who are not executive
officers of the Company, as a group, to the extent such Awards are determinable.

                        AMENDED 1996 STOCK INCENTIVE PLAN

<TABLE>
<CAPTION>
                                   Employees' and       Directors'           Stock         Unrestricted
                                Consultants' Number   Options Number       Restricted      Stock Number
Name and Position                    of Shares          of Shares       Number of Shares    of Shares
- -----------------                    ---------          ---------       ----------------    ---------
<S>                                <C>                <C>                <C>              <C>
John L. Ridihalgh,                      (a)           Not applicable          (a)              (a)
Chairman and Chief                                                                           
Executive Officer                                                                            

David C. Bupp, President and            (a)           Not applicable          (a)              (a)
Chief Operating Officer                                                                      

Louis F. Cosentino, Vice                (a)           Not applicable          (a)              (a)
President, Marketing &                                                                       
Corporate Development                                                                        

William A. Eisenhardt, Ph.D.,           (a)           Not applicable          (a)              (a)
Vice President, Research and                                                                 
Development                                                                                  

J. Kenneth Poggenburg, Jr.,             (a)           Not applicable          (a)              (a)
Ph.D., Vice President,                                                                       
Operations                                                                                   

Executive Group                         (a)           Not applicable          (a)              (a)

Non-Executive Director             Not applicable        35,000(b)       Not applicable   Not applicable
Group

Non-Executive Officer                   (a)           Not applicable     Not applicable        (a)
Employee Group
</TABLE>

(a)   Grants of Options, Restricted Stock and Unrestricted Stock to employees
      and consultants are discretionary with the Committee and are, therefore,
      not currently determinable. See "Compensation of Management" for certain
      information as to grants of Options made previous fiscal years.

(b)   Mr. Hazard, Dr. Krevans, Dr. Moore, Mr. Mueller, Mr. Vromen, Mr. Whitley
      and Mr. Zid each received a grant of an Option to purchase 5,000 shares of
      Common Stock with an exercise price of $13.375 per share subject to the
      approval of the Plan.

Vote Required

      The affirmative vote of the holders of a majority of the shares of Common
Stock present, or represented, and entitled to vote at the Annual Meeting will
be required to approve the Amended Plan. See "General Information--Tabulation,"
above.

Board Recommendation

      The Board unanimously recommends a vote FOR the approval of the Amendment
to the 1996 Stock Incentive Plan.


                                       11
<PAGE>   15

                  SECURITY OWNERSHIP OF PRINCIPAL STOCKHOLDERS,
                   DIRECTORS, NOMINEES AND EXECUTIVE OFFICERS

      The following table sets forth, as of March 31, 1997, certain information
with respect to the beneficial ownership of shares of Common Stock by (i) each
person known to the Company to be the beneficial owner of more than 5 percent of
the outstanding shares of Common Stock, (ii) each Director or nominee for
Director of the Company, (iii) each of the Named Executives (see "Compensation
of Management--Summary Compensation Table"), and (iv) the Company's Directors
and executive officers as a group.

                                               Number of
                                                 Shares
                                              Beneficially           Percent
                 Beneficial Owner               Owned(a)            of Class
- --------------------------------------       --------------        ----------- 
Melvin D. Booth                                    -0-                 (r)
David C. Bupp                                  330,552 (b)             1.4%
John S. Christie                                   187                 (r)
Louis F. Cosentino                              20,034 (c)             (r)
William A. Eisenhardt                           57,856 (d)             (r)
C. Michael Hazard                              552,867 (e)             2.4%
Julius R. Krevans                                7,367 (f)             (r)
Michael P. Moore                                11,367 (g)             (r)
Jerry K. Mueller, Jr                            77,356 (h)             (r)
J. Kenneth Poggenburg, Jr                       53,259 (i)             (r)
John L. Ridihalgh                              502,517 (j)             2.2%
Zwi Vromen                                      80,423 (k)             (r)
J. Frank Whitley, Jr                             2,200 (l)             (r)
James F. Zid                                    12,167 (m)             (r)
All directors and officers as a group        1,863,847 (n)             7.9%
(15 persons)
Kenneth R. McGuire (o)                       1,567,100 (o)             6.9%
The Knowlton/Lee Group (p)                   1,401,460 (p)             6.2%
The TCW Group, Inc. (q)                      1,506,600 (q)             6.6%

(a)   Unless otherwise indicated, the beneficial owner has sole voting and
      dispositive power over these shares subject to the spousal rights, if any,
      of the spouses of those beneficial owners who have spouses.

(b)   This amount includes 291,667 shares issuable upon exercise of options
      which are exercisable within 60 days, 1,686 shares in Mr. Bupp's account
      in the Neoprobe Corporation 401(k) Plan (the "401(k) Plan") and 2,200
      shares held by Mr. Bupp's wife and daughters, as to which latter shares he
      disclaims beneficial ownership, but it does not include 138,933 shares
      issuable upon exercise of options which are not exercisable within 60
      days. Mr. Bupp is one of three trustees of the 401(k) Plan and may, as
      such, share dispositive power over Common Stock held in such plan. The
      401(k) Plan holds an aggregate total of 14,116 shares of Common Stock. Mr.
      Bupp disclaims any beneficial ownership of shares held by the 401(k) Plan
      that are not allocated to his personal account.

(c)   This amount consists of 20,000 shares issuable upon exercise of options
      which are exercisable within 60 days and 34 shares in Mr. Cosentino's
      account in the 401(k) Plan, but does not include 20,000 shares issuable
      upon exercise of options which are not exercisable within 60 days.

(d)   This amount includes 57,333 shares issuable upon exercise of options which
      are exercisable within 60 days and 523 shares in Dr. Eisenhardt's account
      in the 401(k) Plan, but it does not include 34,667 shares issuable upon
      exercise of options which are not exercisable within 60 days.

(e)   This amount includes 2,867 shares issuable upon exercise of options which
      are exercisable within 60 days, 225,000 shares held by Westfield
      Performance Fund, Limited Partnership, over which Mr. Hazard has voting
      and dispositive power, and 325,000 shares held in a client's advisory
      account managed by Mr. Hazard's employer, over which Mr. Hazard has voting
      and dispositive power, but does not include 8,233 shares issuable upon
      exercise of options which are not exercisable within 60 days. Mr. Hazard
      disclaims beneficial ownership of the 325,000 shares held in the advisory
      account and the 225,000 shares held by Westfield Performance Fund, Limited
      Partnership, in excess of his ownership interest in the limited
      partnership.


                                       12
<PAGE>   16

(f)   This amount includes 5,367 shares issuable upon exercise of options which
      are exercisable within 60 days, but does not include 8,233 shares issuable
      upon exercise of options which are not exercisable within 60 days.

(g)   This amount includes 5,367 shares exercisable upon exercise of options
      which are exercisable within 60 days, but does not include 8,233 shares
      issuable upon exercise of options which are not exercisable within 60
      days.

(h)   This amount includes 75,781 shares held by an Ohio limited liability
      company, a member of which is a revocable trust in which Mr. Mueller has a
      beneficial interest and of which he is a trustee. Mr. Mueller has shared
      voting and dispositive power over these shares. This amount also includes
      375 shares held by a company in which Mr. Mueller holds a 25 percent
      interest and 1,200 shares issuable upon exercise of options which are
      exercisable within 60 days, but does not include 7,400 shares issuable
      upon exercise of options which are not exercisable within 60 days.

(i)   This amount includes 43,333 shares issuable upon exercise of options which
      are exercisable within 60 days and 426 shares in Dr. Poggenburg's account
      in the 401(k) Plan, but it does not include 26,667 shares issuable upon
      exercise of options which are not exercisable within 60 days.

(j)   This amount includes 361,667 shares issuable upon exercise of options
      which are exercisable within 60 days, 1,660 shares held in Dr. Ridihalgh's
      account in the 401(k) Plan and 14,750 shares held by Dr. Ridihalgh's wife,
      as to which latter shares he disclaims beneficial own ership, but it does
      not include 140,333 shares issuable upon exercise of options which are not
      exercisable within 60 days.

(k)   This amount includes 5,367 shares issuable upon exercise of options which
      are exercisable within 60 days, but does not include 8,233 shares issuable
      upon exercise of options which are not exercisable within 60 days.

(l)   This amount includes 1,200 shares issuable upon exercise of options which
      are exercisable within 60 days, but does not include 7,400 shares issuable
      upon exercise of options which are not exercisable within 60 days, or any
      shares held by Dow. See "Certain Transactions." Mr. Whitley is an employee
      of Dow and he disclaims beneficial ownership of any shares held by Dow.

(m)   This amount includes 7,867 shares issuable upon exercise of options which
      are exercisable within 60 days and 300 shares in Mr. Zid's IRA, but does
      not include 8,233 shares issuable upon exercise of options which are not
      exercisable within 60 days.

(n)   This amount includes 946,465 shares issuable upon exercise of options and
      warrants which are exercisable within 60 days (which includes 263,898
      shares issuable upon exercise by non-director executive officers) and
      6,592 shares held in the Company's 401(k) Plan. Certain executive officers
      of the Company are the trustees of the 401(k) Plan and may, as such, share
      dispositive power over Common Stock held in such plan. Each trustee
      disclaims any beneficial ownership of shares held by the 401(k) Plan that
      are not allocated to his personal account. The 401(k) Plan holds an
      aggregate total of 14,116 shares of Common Stock. This amount also
      includes the 325,000 shares held in a client's advisory account managed by
      Mr. Hazard's employer and the 225,000 shares held by Westfield Performance
      Fund, Limited Partnership, discussed in note (e) above. This amount does
      not include the shares owned by Dow excluded in note (l) above or 591,235
      shares issuable upon the exercise of options or warrants which are not
      exercisable within 60 days (including 256,002 shares issuable upon
      exercise by non-director executive officers).

(o)   Mr. McGuire's address is 3000 North Clybourn, Hangar 34, Burbank,
      California 91505. This amount includes 17,600 shares held by Mr. McGuire
      as custodian under the Uniform Transfer to Minors Act of California for
      his four children.

(p)   This beneficial owner is a "group" within the meaning of Rule 13d-5 under
      the Securities Exchange Act of 1934. The notice address of the group is
      c/o Mr. Stanley Knowlton, Knowlton Brothers, Inc., 530 Fifth Avenue, New
      York, New York 10036. The following are the members of the group: The
      Family Partnership, L.P.; The Frontier Partnership, L.P.; The Darwin
      Partnership, L.P.; Flagship Partners, Ltd.; Darwin Partners, Ltd.; Barker,
      Lee & Co., Limited Partnership; J.M.R. Barker Foundation; Quaker Hill
      Associates, L.P.; Upland Associates, L.P.; Namakagon Associates, L.P.;
      Family Partners & Co.; Frontier Partners & Co.; Knowlton Brothers, Inc.;
      Knowlton Associates, Inc.; Hugh Knowlton Trust For The Benefit of Erica
      Knowlton; Winthrop Knowlton; Stanley Knowlton; Christopher Knowlton;
      Robert R. Barker; and Dwight E. Lee. This amount includes 144,600 shares
      issuable upon exercise of Class E Redeemable Common Stock Purchase
      Warrants ("Class E Warrants"). The Class E Warrants expired on November
      12, 1996. The Company does not know whether The Knowlton/Lee Group
      exercised its Class E Warrants.

(q)   The TCW Group, Inc. ("TCW") is a parent holding company. TCW's address is
      865 South Figueroa Street, Los Angeles, California 90017. TCW does not
      directly own any of these shares. TCW has indirect ownership of these
      shares because of the following TCW subsidiaries' interests in the shares:
      Trust Company of the West, a California corporation and a bank as defined
      in Section 3(a)(6) of the Securities Exchange Act of 1934; TCW Asset
      Management Company, a California corporation and an Investment Adviser
      registered under Section 203 of the Investment Advisers Act of 1940; and
      TCW Funds Management, Inc., also a California corporation and an
      Investment Adviser registered under Section 203 of the Investment Advisers
      Act of 1940. Robert Day is an individual who may be deemed to control The
      TCW Group, Inc. and its subsidiaries listed above.

(r)   Less than 1 percent.


                                       13
<PAGE>   17

                           COMPENSATION OF MANAGEMENT

Summary Compensation Table

      The following table sets forth certain information concerning the annual
and long-term compensation of the chief executive officer of the Company and the
Company's other four most highly compensated executive officers during the last
fiscal year (the "Named Executives") for the Company's last three fiscal years.

<TABLE>
<CAPTION>
                                                                                 Long Term
                                                                               Compensation
                                                                                  Awards
                                                                                Securities
                                                                                Underlying
                                                     Annual Compensation          Options       All Other
             Name and Principal          Year      Salary             Bonus      (shares)     Compensation(*)
             ------------------          ----      ------             -----       ------      ------------   
<S>                                      <C>     <C>                <C>          <C>            <C>    
John L. Ridihalgh, Ph.D.,                1996    $ 250,000          $ 95,000      20,000        $ 1,500
Chairman and Chief Executive Officer     1995      178,338            50,000     150,000          1,694
                                         1994      149,154            20,000       ---            1,470

David C. Bupp,                           1996    $ 236,250          $ 90,000      20,000        $ 1,500
 President and Chief Operating Officer   1995      156,346            60,000     150,000          1,681
                                         1994      134,135            25,000       ---            1,313

Louis F. Cosentino,                      1996    $ 113,705          $ 56,344      40,000        $   613
  Vice President, Marketing and
  Corporate Development (a)

William A. Eisenhardt, Ph.D.,            1996    $ 167,286          $ 59,051      10,000        $ 1,500
  Vice President, Research and           1995      157,635            31,030      42,000          1,547
  Development                            1994      114,327            15,000      40,000           ---

J. Kenneth Poggenburg, Jr., Ph.D.,       1996    $ 126,730          $ 43,750      10,000        $ 1,448
  Vice President, Operations             1995      120,683            18,056      30,000          1,207
                                         1994       96,779            10,000      40,000           ---
</TABLE>

(*)   Amounts of matching contribution under the Company's 401(k) Plan. Eligible
      employees may make voluntary contributions and the Company may, but is not
      obligated to, make matching contributions based on 20 percent of the
      employee's contribution, up to five percent of the employee's salary.
      Contributions by employees are invested by an independent plan
      administrator in mutual funds and contributions, if any, by the Company
      are made in the form of shares of Common Stock. The 401(k) Plan is
      intended to qualify under section 401 of the Code, which provides that
      employee and Company contributions and income earned on contributions are
      not taxable to the employee until withdrawn from the plan, and that
      Company contributions will be deductible by the Company when made.

(a)   Mr. Cosentino began his employment with the Company in January, 1996.


                                       14
<PAGE>   18

Option Grants in Last Fiscal Year

      The following table presents certain information concerning stock options
granted to the Named Executives during the last fiscal year (1996).

<TABLE>
<CAPTION>
                                                         Individual Grants                            Grant Date Value
                            -----------------------------------------------------------------------   ----------------
                                                   Percent of Total
                            Number of Securities    Options Granted
                             Underlying Options     to Employees in    Exercise Price    Expiration     Grant Date
              Name            Granted (shares)        Fiscal Year         Per Share        Date(a)    Present Value $
              ----            ---------------         -----------         ---------        ----       ---------------
<S>                               <C>                    <C>               <C>            <C>           <C>        
John L. Ridihalgh                 20,000(b)              4.6%              $15.75         1/18/06       $295,000(f)

David C. Bupp                     20,000(b)              4.6%              $15.75         1/18/06       $295,000(f)

Louis F. Cosentino                13,333(c)              3.1%              $15.75         1/18/06       $187,200(g)
                                  13,333(d)              3.1%              $15.75         1/18/06       $170,000(h)
                                  13,333(e)              3.1%              $15.75         1/18/06       $187,200(g)

William A. Eisenhardt             10,000(b)              2.3%              $15.75         1/18/06       $147,500(f)

J. Kenneth Poggenburg, Jr.        10,000(b)              2.3%              $15.75         1/18/06       $147,500(f)
</TABLE>

(a)   The options terminate on the earlier of the Expiration Date, nine months
      after death or disability, 90 days after termination of employment without
      cause or immediately upon termination of employment for cause or by
      resignation.

(b)   Vests as to one-third of these shares on each of the first three
      anniversaries of the date of grant.

(c)   Vests monthly in equal portions over the first 24 months following the
      date of grant.

(d)   Vested upon the completion and implementation of the marketing plan by the
      Company.

(e)   Vests upon the submittal of a Product License Application or European
      Dossier.

(f)   The per share weighted average fair value of these stock options during
      1996 was $14.75 on the date of grant using the Black Scholes option
      pricing model with the following assumptions: an expected life of 4 years,
      an average risk-free interest rate of 5.24%, volatility of 181% and no
      expected dividend rate.

(g)   The per share weighted average fair value of these stock options during
      1996 was $14.04 on the date of grant using the Black Scholes option
      pricing model with the following assumptions: an expected life of 3 years,
      an average risk-free interest rate of 5.24%, volatility of 181% and no
      expected dividend rate.

(h)   The per share weighted average fair value of these stock options during
      1996 was $12.75 on the date of grant using the Black Scholes option
      pricing model with the following assumptions: an expected life of 2 years,
      an average risk-free interest rate of 5.24%, volatility of 181% and no
      expected dividend rate.


                                       15
<PAGE>   19

Fiscal Year End Option Numbers and Values

      The following table sets forth certain information concerning each
exercise of stock options and the number and value of unexercised options held
by the Named Executives at the end of the last fiscal year (December 31, 1996).

<TABLE>
<CAPTION>
                                                           Number of Securities
                                                                Underlying              Value of Unexercised
                                  Shares                    Unexercised Option          In-the-Money Options
                                 Acquired      Value        at Fiscal Year-End:         at Fiscal Year-End:
         Name                  on Exercise   Realized    Exercisable/Unexercisable   Exercisable/Unexercisable
         ----                  -----------   --------    -------------------------   -------------------------
<S>                                <C>       <C>             <C>                      <C>                
 John L. Ridihalgh                  ---        ---           361,667 / 113,333        $3,878,125 / $1,287,500

 David C. Bupp                      ---        ---           291,667 / 113,333        $3,019,875 / $1,287,500

 Louis F. Cosentino                 ---        ---             6,667 / 33,333                --- / ---

 William A. Eisenhardt              ---        ---            56,750 / 35,250           $527,740 / $368,010

 J. Kenneth Poggenburg, Jr.        8,000     $107,250         43,917 / 27,083           $382,510 / $262,865
</TABLE>

Long-Term Incentive Plans - Awards in Last Fiscal Year

The following table presents certain information concerning long-term incentives
awarded to the Named Executives during the last fiscal year (1996).

<TABLE>
<CAPTION>
                                           Number of Shares        Performance or Other Period
         Name                            Units or Other Rights     Until Maturation or Payout
         ----                            ---------------------     --------------------------
<S>                                             <C>                          <C> 
 John L. Ridihalgh (a)                          50,000                       6/5/06
 David C. Bupp (a)                              30,000                       6/5/06
 Louis F. Cosentino                              ---                          ---
 William A. Eisenhardt, Ph.D.                    ---                          ---
 J. Kenneth Poggenburg, Jr., Ph.D.               ---                          ---
</TABLE>

(a)   The terms of the awards which took the form of restricted stock purchase
      agreements are described below under "Employment Agreements."


                                       16
<PAGE>   20

Common Share Performance

      The following graph compares the cumulative total return on the Company's
Common Shares to the cumulative total returns of the Nasdaq Stock Market Index
(U.S.) and the Nasdaq Pharmaceutical Index (an index of pharmaceutical and
bio-technology companies the securities of which are traded on the Nasdaq
National Market) since the Company's initial public offering on November 10,
1992. The graph is based upon an assumed investment of $100.00 in each of the
Company's Common Shares, the Nasdaq Stock Market Index (U.S.) and the Nasdaq
Pharmaceutical Index on November 10, 1992 and dividend reinvestment thereafter.

[The following table was represented as a line chart in the printed material]

- ----------------------------------------------------------
Neoprobe Corporation Common Stock Performance Graph
- ----------------------------------------------------------
- ----------------------------------------------------------
- ----------------------------------------------------------
               Neoprobe     Nasdaq Stock       Nasdaq
Date          Corporation   Market Index   Pharmaceuticals
             Common Stock      (U.S.)          Index
- ----------------------------------------------------------
11-Nov-92      100.0000       100.0000        100.0000
- ----------------------------------------------------------
31-Dec-92      102.1300       107.8700        103.8142
- ----------------------------------------------------------
31-Dec-93      106.3800       123.8200         92.5311
- ----------------------------------------------------------
31-Dec-94       25.5300       121.0300         69.6427
- ----------------------------------------------------------
31-Dec-95      274.4700       171.1700        127.4029
- ----------------------------------------------------------
31-Dec-96      261.7000       210.5500        127.7975
- ----------------------------------------------------------

Compensation Committee Report on Executive Compensation

      Background. The Company is in its early growth phase and it has not yet
begun to mature as a business which can set compensation policies based on
traditional statistical measures of growth and profitability such as sales, net
earnings and return on assets. The management of the Company must identify and
focus on the key initiatives and corporate milestones that will, when achieved,
allow it to attain profitable operations and growth. The purpose of the
Company's compensation philosophy is to attract and provide proper incentives to
high-quality, experienced managers and employees who will establish and attain
these key initiatives and milestones.

      Bio-technology is an industry where growth and success depend upon
attracting highly-trained and qualified personnel. As a group, bio-technology
companies employ higher proportions of personnel with earned doctorate degrees
and other advanced degrees in the sciences, as well as, physicians and surgeons.
In order to attract and hold these employees the Company must provide them with
a sufficient base of cash compensation, as well as opportunities to participate
in the Company's growth. This leads the Company to a compensation philosophy
oriented towards the use of variable compensation and long-term incentives. It
is the Company's philosophy that this program be offered to all employees
commensurate with their responsibilities. To make the high compensation of key
personnel worthwhile to the shareholders, a high proportion of annual
compensation should be at risk against the attaining of key accomplishments and
milestones and a high portion of the total compensation must be at risk against
the return to the long-term shareholders of the Company who have funded its
growth.

      Base Salary. Base pay is only one element of key personnel's compensation
package and it is targeted to be at or below the midpoint of a representative
list of small growing bio-technology companies similar to the Company (the "Peer
Group").


                                       17
<PAGE>   21

      Variable Compensation. Variable compensation has an important role in the
Company's compensation philosophy. It is used to create incentives to attain key
initiatives and milestones in the short to medium term and to place a portion of
compensation at risk against the attaining of those targets. The Committee sets
a total amount of variable compensation based on a percentage of base salary.
The total amount available is targeted above the midpoint of the variable
compensation of the Peer Group but the amount paid is based on the elements of
corporate financial performance and the achievement of specific near-term
objectives judged to be important to the Company and established in advance by
the Compensation Committee. For example, during 1996 those targets included
filing of the Company's biological license applications for its initial products
with the United States Food and Drug Administration and comparable European
authorities and the implementation of the Company's strategic alliance with
United States Surgical Corporation.

      Long-Term Incentive Compensation. Stock options provide the principal
vehicle for long-term incentive compensation. Options are issued under the
Company's 1994 and 1996 Stock Option Plans. The target levels for option grants
are set at or above the midpoint of the Peer Group. By their nature, options
directly compensate employees to the extent that long-term investors achieve
high rates of return. Options are also a key element in being able to obtain and
retain experienced and skilled employees. All options are granted at market.
Many options have significant vesting conditions in addition to longevity such
as the attainment of corporate and individual goals. The options are granted to
all levels of employees in order to provide incentives and to minimize cash
compensation.

      Chief Executive Officer Compensation. Dr. Ridihalgh's 1996 compensation
consisted of base salary, variable compensation and stock options. During 1996,
Dr. Ridihalgh entered into a new Employment Agreement, the terms of which are
described under the heading "Compensation of Management - Employment
Agreements." Dr. Ridihalgh's base salary under the contract was set in line with
the philosophy described above. During 1996, Dr. Ridihalgh realized variable
compensation opportunities based on the achievement of corporate goals including
those described above and was granted options to purchase 20,000 shares of
stock, the terms of which are described above under the heading "Compensation of
Management - Employment Agreements." During 1997, the Committee intends to grant
variable compensation opportunities and stock options to Dr. Ridihalgh in
accordance with the philosophy outlined above.

      Internal Revenue Code Provisions. Under Section 162(m) of the Code,
compensation paid by the Company to a Named Executive which is in excess of
$1,000,000 in a year will be nondeductible by the Company for purposes of
determining its federal taxable income unless such compensation is paid under a
performance-based plan which is approved by the stockholders of the Company.
Under the Internal Revenue Service regulations promulgated under Section 162(m),
the Company's 1994 and 1996 Stock Option Plans should be deemed to be
performance-based compensation plans and amounts realized by the Named
Executives under such plans should continue to be deductible by the Company.
Because of the favorable treatment of the Company's Stock Option Plans and the
remoteness of the possibility that base compensation and cash variable
compensation levels will exceed $1,000,000 during fiscal 1997 and the years
thereafter, the Committee did not consider the impact of Section 162(m) on its
decisions concerning compensation.

      Compensation Committee: J. Frank Whitley, Jr. (Chairman), Julius R.
Krevans and James F. Zid.

Employment Agreements

      John L. Ridihalgh is employed under a three-year employment agreement
effective January 1, 1996. The agreement provides for a base salary of $250,000,
$262,500 and $275,500 for the calendar years 1996, 1997 and 1998, respectively.
Dr. Ridihalgh will be paid a bonus of $12,500 upon the occurrence of any of the
following three events during the term of the employment: entering into a
strategic alliance for the marketing of any RIGScan(R) products in the United
States; obtaining United States Food and Drug Administration ("FDA") approval
for a Product License Application ("PLA") for a RIGScan product; or obtaining
equivalent regulatory approval for a RIGScan product from the European
regulatory authorities. Other bonuses are payable at the discretion of the Board
of Directors based on the performance of the Company and Dr. Ridihalgh. The
employment agreement provides for a two year non-competition agreement after the
end of the term of employment. Dr. Ridihalgh is a shareholder in Cira
Technologies, Inc. ("Cira") which is developing a process for treating chronic
infectious diseases using activated cellular therapy. The Company waived any
claim that the stock ownership of Dr. Ridihalgh in Cira and his participation in
the management thereof are violations of the employment agreement. If a change
in control event occurs with respect to the Company and the employment of Dr.
Ridihalgh is concurrently or subsequently terminated (i) without cause (cause is
defined as any


                                       18
<PAGE>   22

willful breach of a material duty by Dr. Ridihalgh in the course of his
employment or willful and continued neglect of his duty as an employee), (ii)
the term of the agreement expires or (iii) Dr. Ridihalgh resigns because his
authority, responsibilities or compensation have materially diminished, a
material change occurs in his working conditions or the Company breaches the
agreement, Dr. Ridihalgh will be paid a severance payment equal to twice his
annual base salary (less amounts paid as Dr. Ridihalgh's salary and benefits
that continue for the remaining term of the agreement if his employment is
terminated without cause). A change in control includes (a) the acquisition,
directly or indirectly, by a person (other than the Company or an employee
benefit plan established by the Board of Directors) of beneficial ownership of
15 percent or more of the Company's securities with voting power in the next
meeting of holders of voting securities to elect the Directors; (b) a majority
of the Directors elected at any meeting of the holders of the Company's voting
securities are persons who were not nominated by the Company's then current
Board of Directors or an authorized committee thereof; (c) the stockholders of
the Company approve a merger or consolidation of the Company with another
person, other than a merger or consolidation in which the holders of the
Company's voting securities issued and outstanding immediately before such
merger or consolidation continue to hold voting securities in the surviving or
resulting corporation (in the same relative proportions to each other as existed
before such event) comprising eighty percent (80%) or more of the voting power
for all purposes of the surviving or resulting corporation; or (d) the
stockholders of the Company approve a transfer of substantially all of the
assets of the Company to another person other than a transfer to a transferee,
eighty percent (80%) or more of the voting power of which is owned or controlled
by the Company or by the holders of the Company's voting securities issued and
outstanding immediately before such transfer in the same relative proportions to
each other as existed before such event. Dr. Ridihalgh's compensation will
continue for the full term of the agreement if his employment is terminated
without cause.

      In June 1996, the Company and Dr. Ridihalgh also entered into a restricted
stock purchase agreement under which Dr. Ridihalgh purchased 50,000 shares of
Common Stock for a purchase price equal to the par value of $.001 per share. Dr.
Ridihalgh may not transfer or sell any of the restricted shares unless and until
they vest. Dr. Ridihalgh will forfeit any portion of the restricted shares that
has not vested (and the Company will refund the purchase price paid) on the
earliest of the termination of his employment under the employment agreement for
any reason unless the Company is, at the time of termination for death or
disability, actively engaged in negotiations that could reasonably be expected
to lead to a change in control (as defined above) or the tenth anniversary of
the date of the employment agreement. The restricted shares that have not
previously been forfeited will vest if and when there is a change in control of
the Company (as defined above). Except for these restrictions on transfer and
possibilities of forfeiture, Dr. Ridihalgh has all other rights with respect to
the restricted shares, including the right to vote such shares and receive cash
dividends. The Company has not recognized any expense under the employment
agreement due to the contingent nature of the vesting provision and the risk of
forfeiture.

      Upon the extension of the employment agreement in February 1995, Dr.
Ridihalgh was granted options to purchase 150,000 shares of Common Stock at an
exercise price of $2.50 per share (the then current market price). Such options
terminate on the earlier of 10 years after the date of grant, nine months after
death, six months after termination of employment due to disability or two years
after any other termination of employment. The options will vest in three equal
tranches, one of which will vest upon the occurrence of any of the following
three events: entering into a strategic alliance for the marketing of any
RIGScan products in the United States; obtaining FDA approval for a PLA for a
RIGScan product; or obtaining equivalent regulatory approval for a RIGScan
product from the European regulatory authorities. All previously unvested option
shares will vest if there is a change in control (as defined therein) and half
of the previously unvested option shares will vest upon termination of Dr.
Ridihalgh's employment by the Company without cause. In January 1996, Dr.
Ridihalgh was granted options to purchase 20,000 shares of Common Stock at an
exercise price of $15.75 per share. Such options terminate on the earlier of 10
years after the date of grant, nine months after death or disability, 90 days
after termination of employment without cause, or immediately upon termination
of employment by resignation. The options will vest as to one-third of the
shares originally subject to the option on each anniversary of the date of
grant. All previously unvested option shares will vest if there is a change of
control (as defined above).

      David C. Bupp is employed under a three-year employment agreement
effective January 1, 1996. The employment agreement provides for a base salary
of $225,000, $236,300 and $248,000 for the calendar years 1996, 1997 and 1998,
respectively. Other than the compensation provisions, Mr. Bupp's employment
agreement has substantially the same terms as Dr. Ridihalgh's agreement (see
above). In June 1996, the Company and Mr. Bupp entered into a restricted


                                       19
<PAGE>   23

stock purchase agreement under which Mr. Bupp purchased 30,000 shares of Common
Stock for a purchase price equal to the par value of $.001 per share. The
vesting provisions and other terms of the restricted stock purchase agreement
are substantially the same as Dr. Ridihalgh's restricted stock purchase
agreement (see above). Upon the extension of the employment agreement in
February 1995, Mr. Bupp was granted options to purchase 150,000 shares of Common
Stock on the same terms as the options granted to Dr. Ridihalgh in February 1995
(see above). In January 1996, Mr. Bupp was granted options to purchase 20,000
shares of Common Stock on the same terms as the options granted to Dr.
Ridihalgh in January 1996 (see above).

Compensation of Non-Employee Directors

      Non-employee Directors who are neither legal counsel to the Company nor
affiliated with a principal stockholder of the Company receive a quarterly
retainer of $2,500 and a fee of $1,000 for each board meeting attended, as well
as reimbursement for travel expenses incurred in connection with attending
meetings. Each such Director will also be granted an option to purchase 5,000
shares of Common Stock which vest over a three-year period and have an exercise
price equal to no less than the market price at the time of grant. Other
Directors do not receive any compensation for their services as Directors.

      Effective March 1, 1997, members of committees of the Board of Directors
will be paid $500 per committee meeting for committee meetings held in
conjunction with regular board meetings, and $800 per committee meeting for
committee meetings not held in conjunction with regularly scheduled board
meetings.

                              CERTAIN TRANSACTIONS

      In 1991 and 1992, Neoprobe entered into agreements with The Dow Chemical
Company ("Dow"), which at that time was a principal stockholder of the Company,
pursuant to which Dow and Neoprobe agreed to coordinate their research and
development activities relative to the commercialization of RIGS products and
Neoprobe was granted certain rights. Under the agreements, Dow (i) granted to
Neoprobe an exclusive global, commercial sublicense to use CC49 as a RIGS
technology product, (ii) agreed to grant to Neoprobe, upon its request and after
approval by NCI/NIH, a sublicense to any other antibody under Dow's commercial
license agreement with NCI/NIH, (iii) granted to Neoprobe an exclusive global
license to Dow's proprietary iodination technology which may be used by Neoprobe
to radiolabel antibodies for RIGS system products and (iv) licensed or
sublicensed certain other targeting agents for use as RIGS technology products.
The agreements provide that Neoprobe is obligated to pay Dow royalties on
certain RIGS system antibody product revenues, part of which compensates Dow for
royalties payable under Dow's license agreement with NCI/NIH. Additional
royalties may be payable if Dow's technology is used in the commercial
production of RIGS system products. If Neoprobe fails to comply with certain
financial and timing requirements of the sublicense, the rights under such
sublicense may revert back to Dow.

      Neoprobe's sublicense of CC49 from Dow is subject to a commercial license
agreement between Dow and NCI/NIH under which NCI/NIH reserved the right to use
CC49 for government purposes. If the Dow-NCI/NIH commercial license agreement is
terminated for any reason, including a default by Dow, the Dow-NCI/NIH
commercial license agreement allows Neoprobe to apply for a license for
antibodies previously granted by Dow to Neoprobe (subject to approval and
acceptance by NCI/NIH). If the Dow-NCI/NIH commercial license agreement is
terminated, the Dow-Neoprobe agreement allows Neoprobe to either obtain a
license directly from NCI/NIH (subject to approval and acceptance by NCI/NIH) or
to terminate provisions of the Dow-Neoprobe agreement that relate to the
Dow-NCI/NIH commercial license agreement.

      In May 1996, Neoprobe and Dow executed an agreement under which Dow
granted Neoprobe global rights to certain technology related to targeting
agents, radiolabeling and radioimmunotherapy products developed by Dow
researchers. Upon completion, the global licenses will provide Neoprobe with
global access to technology covered by issued patents for use in the development
of RIGS and radioimmunotherapy products. Dow received 124,805 shares of Common
Stock in exchange for the technology rights. Dow currently holds 847,920 shares
of Common Stock.


                                       20
<PAGE>   24

      Mueller and Smith, L.P.A., has performed legal services for the Company
since the inception of the Company and continues to serve as the Company's
patent counsel. Jerry K. Mueller, Jr., a director and officer of the Company, is
a partner of that law firm. Fees related to services performed by that firm were
approximately $140,000 and approximately $61,000 in out-of-pocket costs and
expenses were incurred for fiscal year ended 1996. Mr. Mueller's term as a
Director will expire on the date of the Annual Meeting.

      Dr. Richard Olsen, an emeritus professor of veterinary pathobiology at
OSU, and Dr. John Ridihalgh, Chairman of the Company, invented a process for
treating chronic infectious and/or autoimmune diseases using activated cellular
therapy, conducted tests of their invention on animals and filed an application
for a United States patent thereon. In March 1996, Dr. Ridihalgh and the
Company, represented by a committee of independent directors, agreed that a
newly organized corporation, Cira, would exploit the process. The Company
received 10 percent of the originally issued shares in Cira and the remainder
was divided among Drs. Ridihalgh and Olsen and their colleagues, including Jerry
K. Mueller, Jr. who acted as their patent counsel. The Company and Cira also
executed a Technology Option Agreement, under which Cira granted the Company an
option to acquire exclusive world-wide licenses to Cira's activated cellular
therapy for the treatment of human immunodeficiency virus infected patients and
chronic infectious and/or autoimmune disease in humans and the Company agreed to
support a Phase I clinical trial of this process on up to 40 patients at a cost
not to exceed $500,000. The Company and Cira also cross licensed improvements in
activated cellular therapy. In addition to technology rights, the Company
obtained an option to increase its interest in Cira by 15%. The exercise price
of this option is 15% of the fair market value of Cira's outstanding securities
on the earlier of the third anniversary of a license agreement under the
Technology Option Agreement, or the commencement of a pivotal clinical trial
study, subject to a minimum of $1.95 million and a maximum of $4.5 million.

      Mr. Vromen is a partner in Reico, Ltd. Reico, Ltd. received $48,000 in
fiscal year 1996 as compensation for services which Mr. Vromen rendered to
Neoprobe (Israel), Ltd. Neoprobe (Israel), Ltd. is a subsidiary of the Company.

    FORMS 3, 4 AND 5; SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

      This disclosure relates to events occurring in 1996. An untimely Form 3
was filed with the Securities and Exchange Commission for Joseph Bianchine,
Vice-President - Clinical Research and Medical Director, and four transactions
in Company securities were reported to the Securities and Exchange Commission on
untimely Forms 4 and one transaction was reported to the Securities and Exchange
Commission on an untimely amendment to a Form 5 for Trudie Seeger, Vice
President - Regulatory Affairs.

      The Company does not know of any other failures to make filings required
by Section 16 on a timely basis by any of its directors, executive officers or
beneficial owners of 10% or more of its equity securities.

                             INDEPENDENT ACCOUNTANTS

      Coopers & Lybrand L.L.P. served as the Company's independent accountants
for the fiscal year 1996 which ended December 31, 1996, and has audited the
Company's financial statements for each of the past three fiscal years. At the
suggestion of management, the Audit Committee has recommended the retention of
Coopers & Lybrand L.L.P. as the Company's independent accountants for the 1997
fiscal year.

      A representative of Coopers & Lybrand L.L.P. is expected to be present at
the Annual Meeting. The representative will have an opportunity to make a
statement if he so desires and is expected to be available to respond to
appropriate questions of stockholders.


                                       21
<PAGE>   25

                                 OTHER BUSINESS

      The Board of Directors does not intend to present, and has no knowledge
that others will present, any other business at the meeting. If, however, any
other matters are properly brought before the meeting, it is intended that the
persons named in the enclosed proxy will vote the shares represented thereby in
accordance with their best judgment.

                         COST OF SOLICITATION OF PROXIES

      The cost of this solicitation will be paid by the Company. The Company may
request persons holding shares in their names for others to forward soliciting
materials to their principals to obtain authorization for the execution of
proxies, and the Company will reimburse such persons for their expenses in so
doing.

                              STOCKHOLDER PROPOSALS

      A stockholder proposal intended for inclusion in the proxy statement and
form of proxy for the Annual Meeting of Shareholders of the Company to be held
in 1998 must be received by the Company before December 24, 1997, at its
executive offices, Attention: John Schroepfer.

      A stockholder who wishes to nominate a candidate for election to the Board
of Directors must follow the procedures put forth in Article III, Section 2 of
the Company's By-Laws. A copy of these procedures is available upon request from
the Company at 425 Metro Place North, Suite 400, Dublin, Ohio 43017-1367,
Attention: John Schroepfer. In order for a stockholder to nominate a candidate
for the Board of Directors election at the 1998 Annual Meeting, notice of the
nomination must be delivered to the Company's executive offices, Attention: John
Schroepfer, before December 24, 1997.


                                       22
<PAGE>   26
 
       NEOPROBE CORPORATION    THIS PROXY IS SOLICITED BY THE BOARD OF DIRECTORS
 
           The undersigned hereby appoints John L. Ridihalgh and David C. Bupp,
       and each of them, severally, with full power of substitution, as proxies
       for the undersigned, and hereby authorizes them to represent and to vote,
       as designated below, all of the shares of Common Stock, par value $.001
       per share, of Neoprobe Corporation held of record by the undersigned on
       April 4, 1997, at the Annual Meeting of Stockholders to be held on May
       29, 1997, or any adjournment thereof, with all the power the undersigned
       would possess if present in person.
 
       THE BOARD OF DIRECTORS RECOMMENDS ADOPTION OF THE PROPOSAL AND THE
       ELECTION OF ALL NOMINEES.
 
          1. To elect as directors the nominees named below for a term of one
             year and until their successors are duly elected and qualified.
 
          NOMINEES: MELVIN D. BOOTH, JOHN S. CHRISTIE, AND J. FRANK WHITLEY, JR.
 
          [ ] FOR all nominees listed above (except as marked to the
              contrary) 

          [ ] WITHHOLD AUTHORITY to vote for all nominees listed above
 
             (INSTRUCTIONS: To withhold authority to vote for any individual
             nominee, strike a line through the nominee's name listed above.)
 
          2. Approval of the Amendment to the 1996 Stock Incentive Plan.
 
            [ ] FOR             [ ] AGAINST             [ ] ABSTAIN
 
                 (Continued, to be dated and signed, on the other side.)
 
                          (Continued from the other side)
 
       In their discretion, the proxies are authorized to vote upon such other
    business as may properly come before the Annual Meeting of Stockholders or
    any adjournment thereof.
 
       THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED
    HEREIN BY THE UNDERSIGNED STOCKHOLDER. IF NO DIRECTION IS MADE, THIS PROXY
    WILL BE VOTED IN FAVOR OF THE PROPOSAL AND FOR THE ELECTION OF ALL NOMINEES
    LISTED ABOVE.
 
       The undersigned hereby acknowledges receipt with this Proxy of a copy of
    the Notice of Annual Meeting and Proxy Statement dated April 18, 1997 and a
    copy of the Company's 1996 Annual Report to Stockholders.
 
                                                Date:____________________ , 1997
 
                                                --------------------------------
                                                Signature
 
                                                --------------------------------
                                                Signature (if held jointly)
 
                                                IMPORTANT: Please sign exactly
                                                as name or names appear to the
                                                left. When shares are held by
                                                joint tenants, both should sign.
                                                When signing as attorney,
                                                executor, administrator, trustee
                                                or guardian, please give full
                                                title as such. Corporations
                                                should sign in their full
                                                corporate name by their
                                                president or other authorized
                                                officer. If a partnership,
                                                please sign in partnership name
                                                by an authorized person.
 
    PLEASE MARK, SIGN, DATE AND RETURN THE PROXY CARD PROMPTLY USING THE
    ENCLOSED ENVELOPE.

<PAGE>   1

                                                                 Exhibit 10.2.37

                              NEOPROBE CORPORATION

                            1996 STOCK INCENTIVE PLAN

                             ----------------------

                                January 18, 1996

                             ----------------------

                             Amended March 13, 1997

                             ----------------------

                                P R E A M B L E :

      1. Neoprobe Corporation, a Delaware corporation ("Neoprobe" or the
"Company") by means of this 1996 Stock Incentive Plan (the "Plan"), desires to
attract and retain capable directors, employees and consultants and to provide
them with long term incentives to continue their services to the Company, to
maximize the value of the Company to its stockholders and to acquire a
continuing ownership interest in the Company.

      2. The Company has determined that the foregoing objectives will be
promoted by granting Awards (as hereinafter defined) under this Plan to certain
directors and employees of and consultants to the Company and its subsidiaries,
if any, pursuant to this Plan.

                                   T E R M S :

Article 1. Definitions.

      Section 1.1. General.  Certain words and phrases used in this Plan shall
have the meanings given to them below in this section:

      "Award" means a grant of Options or Unrestricted Stock or the right to
purchase Restricted Stock under the Plan.

      "Board of Directors" means the board of directors of Neoprobe.

      "Change in Control" means (a) the acquisition by any person (defined for
the purposes of this definition to mean any person within the meaning of Section
13(d) of the Exchange Act), other than Neoprobe or an employee benefit plan
created by the Board of Directors for the benefit of its Employees, either
directly or indirectly, of the beneficial ownership (determined under Rule 13d-3
of the Regulations promulgated by the SEC under Section 13(d) of the Exchange
Act) of securities issued by Neoprobe having fifteen percent (15%) or more of
the voting power of all the voting securities issued by Neoprobe in the election
of Directors at the next meeting of the holders of voting securities to be held
for such purpose; (b) the election of a majority of the Directors elected at any
meeting of the holders of voting securities of Neoprobe who are persons who were
not
<PAGE>   2

nominated for such election by the Board of Directors or a duly constituted
committee of the Board of Directors having authority in such matters; (c) the
approval by the stockholders of Neoprobe of a merger or consolidation with
another person, other than a merger or consolidation in which the holders of
Neoprobe's voting securities issued and outstanding immediately before such
merger or consolidation continue to hold voting securities in the surviving or
resulting corporation (in the same relative proportions to each other as existed
before such event) comprising eighty percent (80%) or more of the voting power
for all purposes of the surviving or resulting corporation; or (d) the approval
by the stockholders of Neoprobe of a transfer of substantially all of the assets
of Neoprobe to another person other than a transfer to a transferee, eighty
percent (80%) or more of the voting power of which is owned or controlled by
Neoprobe or by the holders of Neoprobe's voting securities issued and
outstanding immediately before such transfer in the same relative proportions to
each other as existed before such event.

      "Code" means the Internal Revenue Code of 1986 and the regulations
thereunder, as now in effect or hereafter amended.

      "Committee" means the Committee of the Board of Directors that administers
the Plan under Section 2.1 below.

      "Common Stock" means the common stock, par value $.001 per share, of the
Company.

      "Consultant" means any person who provides services to the Company or any
Subsidiary (other than in connection with the offer or sale of securities of the
Company or any Subsidiary in a capital raising transaction), who is neither an
Employee nor a Director and who is a consultant or an adviser to the Company or
any Subsidiary within the meaning of General Instruction A.1. to Form S-8
promulgated by the SEC under the Securities Act of 1933.

      "Date of Grant" means the date an Award is first granted.

      "Director" means a member of the Board of Directors.

      "Effective Date" means the date this Plan is first adopted by the Board of
Directors.

      "Employee" means any common law employee of Neoprobe or any Subsidiary of
Neoprobe.

      "Exchange Act" means the Securities Exchange Act of 1934.

      "Exercise Price" means, with respect to an Option, the amount of
consideration that must be delivered to the Company in order to purchase a
single Share thereunder.

      "Fair Market Value of a Share" means the amount determined to be the fair
market value of a single Share by the Committee based upon the trading price of
the Shares, their offering price in public and private offerings by the Company
and such other factors as it deems relevant. In the absence of such a
determination, the Fair Market Value of a Share shall be deemed to be (a) if the
Shares are listed or admitted to trading on a national securities exchange or
the Nasdaq National Market, the per Share closing price regular way on the
principal national securities exchange or the Nasdaq National Market on which
the Shares are listed or admitted to trading on the day prior to the date of
determination or, if no closing price can be determined for the date of
determination, the most recent date for which such price can reasonably be
ascertained, or (b) if the Shares are not listed or admitted to trading on a
national securities exchange or the Nasdaq National Market, the mean between the
representative bid and asked per Share prices in the over-the-counter market at
the closing of the day prior to the date of determination or the most recent
such bid and asked prices then available, as reported by NASDAQ or if the Shares
are not then quoted by NASDAQ as furnished by any market maker selected from
time to time by Neoprobe for that purpose.

      "Grantee" means any Participant to whom an Award has been granted.

      "Holder" means any Grantee who holds a valid Award and any heir or legal
representative to whom such Grantee's Award has been transferred by will or the
laws of descent and distribution.


                                      -2-
<PAGE>   3

      "Incentive Stock Option" or "ISO" means an Option intended to comply with
the terms and conditions set forth in Section 422 of the Code.

      "Meeting Date" means the date of the first regular  meeting of the Board
of Directors in each fiscal year of the Company. For 1997, the Meeting Date
shall be deemed to be March 13, 1997.

      "Nonqualified Option" means a Stock Option other than an Incentive Stock
Option.

      "Officer" means an officer of the Company as defined in 17 C.F.R. ss.
240.16a-1(f) as now in effect or hereafter amended.

      "Option" or "Stock Option" means a right granted under Article 5 or 6 of
the Plan to a Participant to purchase a stated number of Shares.

      "Option Agreement" means an agreement evidencing an Option substantially
in the form of Exhibit A or Exhibit B hereto.

      "Parent" means a parent of a given corporation as such term is defined in
Section 424(e) of the Code.

      "Participant" means a person who is eligible to receive and has received
an Award under the Plan.

      "Plan" means this Plan as it may be amended or restated from time to time.

      "Restricted Stock" means Shares purchased under Article 7 of the Plan that
are subject to restrictions on transfer and risks of forfeiture under the Plan.

      "Restricted Stock Purchase Agreement" means a Restricted Stock Purchase
Agreement in the form of Exhibit C attached hereto.

      "Rule 16b-3" means Rule 16b-3 (17 C.F.R. ss. 240.16b-3) promulgated under
Section 16(b) of the Exchange Act as now in effect or hereafter amended.

      "SEC" means the Securities and Exchange Commission.

      "Shares" means shares of Common Stock.

      "Subsidiary" means a subsidiary of a given corporation as such term is
defined in Section 424(f) of the Code.

      "Ten Percent Stockholder" means a person who owns stock possessing more
than ten percent (10%) of the total combined voting power of all classes of
stock of the Company or any Parent or Subsidiary of the Company. Ownership shall
for the purposes of the previous sentence be determined under the rules set
forth in Section 424 of the Code.

      "Termination without cause" means a termination of the employment or
consulting relationship of a Grantee that is not for cause and is not occasioned
by the resignation, death or disability of the Grantee.

      "Unrestricted Stock" means Shares granted to a Grantee under Article 9 of
the Plan.

      Section 1.2. Accounting Terms. All accounting terms not specifically
defined herein shall be construed in accordance with generally accepted
accounting principles.

      Section 1.3. Effect of Definitions. The definitions set forth in Section
1.1 above shall apply equally to the singular, plural, adjectival, adverbial and
other forms of any of the words and phrases defined regardless of whether they
are capitalized.

Article 2. Administration.

    Section 2.1. Committee. The Plan shall be administered by a committee of the
Board of Directors consisting of two or more Directors, each of whom is a
"Non--Employee Director" as described in paragraph (b)(3) of Rule 16b-3 and is
an "outside director" as described in Code Section 162(m) and the regulations
thereunder (the "Committee"). Unless the Board of Directors designates another
of its committees to administer the Plan, the Plan shall be administered by a
committee consisting of those members of the Compensation Committee of the Board
of Directors who are disinterested persons and are outside directors, but, if
the Compensation Committee is abolished or its membership does not contain two
persons who do comply with the requirements of the first sentence of this
Section 2.1, the Board of Directors shall either reconstitute the Compensation


                                      -3-
<PAGE>   4

Committee in compliance with or create another Committee that complies with the
requirements of the first sentence of this Section 2.1 to administer the Plan.
The Committee may be referred to as the Stock Option Committee.

      Section 2.2. Authority. Subject to the express provisions of the Plan and
in addition to the powers granted by other sections of the Plan, the Committee
has the authority, in its discretion, to: (a) determine the Participants, grant
Awards and determine their timing, pricing and amount; (b) define, prescribe,
amend and rescind rules, regulations, procedures, terms and conditions relating
to the Plan; (c) make all other determinations necessary or advisable for
administering the Plan, including, but not limited to, interpreting the Plan,
correcting defects, reconciling inconsistencies and resolving ambiguities; (d)
review and resolve all claims of Employees, Grantees and Participants; and (e)
delegate to the Officers the authority to select Grantees under Article 5 (other
than Officers) and grant Awards to such Grantees having terms and in aggregate
amounts determined by the Committee. The actions and determinations of the
Committee on matters related to the Plan shall be conclusive and binding upon
the Company and all Employees, Grantees and Participants.

Article 3. Shares.

      Section 3.1. Number. The aggregate number of Shares in respect of which
Awards may be granted under the Plan shall not exceed one million five hundred
thousand (1,500,000), which number of Shares is hereby reserved for issuance
under the Plan out of the authorized but unissued Shares.

      Section 3.2. Cancellations. If any Awards granted under the Plan are
canceled, terminate or expire for any reason without having been exercised in
full, the Shares related to the unexercised portion of an Award shall be
available again for the purposes of the Plan. If any Shares purchased under the
Plan are forfeited for any reason, the Shares shall be available again for
purposes of the Plan.

      Section 3.3. Anti-Dilution.

            (a) If the Shares are split or if a dividend of Shares is paid on
the Shares, the number of Shares for which each then outstanding Award is
exercisable or which is then Restricted Stock and the number of Shares as to
which Awards may be granted under this Plan shall be increased automatically by
the ratio between the number of Shares outstanding immediately after such event
and the number of Shares outstanding immediately before such event and the
Exercise Price thereof shall be decreased automatically by the same ratio, and
if the Shares are combined into a lesser number of Shares, the number of Shares
for which each then outstanding Award is exercisable or which is then Restricted
Stock and the number of Shares as to which Awards may be granted under the Plan
shall be decreased automatically by such ratio and the Exercise Price thereof
shall be increased automatically by such ratio.

            (b) In the event of any other change in the Shares, through
recapitalization, merger, consolidation or exchange of shares or otherwise,
there shall automatically be substituted for each Share subject to an
unexercised Award or which is then Restricted Stock and each Share available for
additional grants of Awards, the number and kind of shares or other securities
into which each outstanding Share was changed, and the Exercise Price shall be
increased or decreased proportionally so that the aggregate Exercise Price for
the securities subject to each Award shall remain the same as immediately before
such event; and the Committee may make such further equitable adjustments in the
Plan and the then outstanding Awards and Restricted Stock Purchase Agreements as
it deems necessary and appropriate including, but not limited to, changing the
number of Shares reserved under the Plan or covered by outstanding Awards, the
Exercise Price of outstanding Awards and Restricted Stock Purchase Agreements
and the vesting conditions of outstanding Awards and Restricted Stock Purchase
Agreements.

      Section 3.4. Source. Except as otherwise determined by the Board of
Directors, the Shares issued under the Plan shall be authorized but unissued
Shares. However, Shares which are to be delivered under the Plan may be obtained
by the Company from its treasury, by purchases on the open market or from
private sources, or by issuing authorized but unissued Shares. The proceeds of
the exercise of any Award shall be general corporate funds of the Company. No
Shares may be sold under any Option or


                                      -4-
<PAGE>   5

Restricted Stock Purchase Agreement for less than the par value thereof. No
fractional Shares shall be issued or sold under the Plan nor will any cash
payment be made in lieu of fractional Shares.

      Section 3.5. Rights of a Stockholder. Except as otherwise provided in any
Restricted Stock Purchase Agreement, no Grantee or other person claiming under
or through any Grantee shall have any right, title or interest in or to any
Shares allocated or reserved under the Plan or subject to any Award except as to
such Shares, if any, for which certificates representing such Shares have been
issued to such Grantee.

      Section 3.6. Securities Laws. No Award shall be exercised nor shall any
Shares or other securities be issued or transferred pursuant to an Award unless
and until all applicable requirements imposed by federal and state securities
laws and by any stock exchanges upon which the Shares may be listed, have been
fully complied with. As a condition precedent to the exercise of an Award or the
issuance of Shares pursuant to the grant or exercise of an Award, the Company
may require the Grantee to take any reasonable action to meet such requirements
including providing undertakings as to the investment intent of the Grantee,
accepting transfer restrictions on the Shares issuable thereunder and providing
opinions of counsel, in form and substance acceptable to the Company, as to the
availability of exemptions from such requirements.

Article 4. Eligibility.

      Section 4.1. Article 5. Only Employees and Consultants who are not members
of the Committee, shall be eligible to receive Options under Article 5 below.

      Section 4.2. Article 6. Only Directors who are not Employees, shall be
eligible to receive Options under the provisions of Article 6 below.

      Section 4.3. Article 7. Only Officers shall be eligible to purchase
Restricted Stock under Article 7 below.

      Section 4.4. Article 8. Only Employees and Consultants who are not members
of the Committee shall be eligible to receive Unrestricted Stock under Article 8
below.

Article 5. Stock Options.

      Section 5.1. Determinations. The Committee shall determine which eligible
Employees or Consultants shall be granted Options, the number of Shares for
which the Options may be exercised, the times when they shall receive them and
the terms and conditions of individual Option grants (which need not be
identical); provided, however, that the maximum number of Shares with respect to
which Options may be granted during any fiscal year of the Company to any
Employee shall be five hundred thousand (500,000). The Committee may delegate
the authority granted to it in this Section 5.1 pursuant to clause (e) of
Section 2.2 above.

      Section 5.2. Exercise Price. The Committee shall determine the Exercise
Price of each Option at the time that it is granted, but in no event shall the
Exercise Price of an Option be less than the Fair Market Value of a Share on the
Date of Grant. If no express determination of the Exercise Price of an Option is
made by the Committee, the Exercise Price thereof is equal to the Fair Market
Value of a Share on the Date of Grant.

      Section 5.3. Term. Subject to the rule set forth in the next sentence, the
Committee shall determine the term during which an Option is exercisable at the
time that it is granted. No Option shall be exercisable after the expiration of
ten (10) years from the Date of Grant. If no express determination of the times
when Options are exercisable is made by the Committee:

            (a) each Option shall vest and first become exercisable as to one
third (1/3) of the Shares originally subject to the Option (subject to the rule
set forth in Section 5.4(c) below) on each anniversary of the Date of Grant
provided the Grantee thereof has been an Employee or a Consultant, as the case
may be, continuously during the time beginning on the Date of Grant and ending
on the date when such portion of the Option first becomes exercisable; and

            (b) each Option shall lapse and cease to be exercisable upon the
earliest of (i) the expiration of ten (10) years from the Date of Grant, (ii)
subject to


                                      -5-
<PAGE>   6

the rule set forth in Section 5.4(d) below, nine (9) months after the Grantee
ceases to be an Employee or Consultant because of his death or disability, (iii)
ninety (90) days after the Grantee's employment with or services to the Company
or any Subsidiary are terminated by the Company or such Subsidiary without
cause, or (iv) immediately upon termination of the Grantee's employment with or
services to the Company or any Subsidiary by the Company or any Subsidiary for
cause or by the Grantee's resignation.

      Where both an Incentive and a Nonqualified Option are granted, the number
of Shares which become exercisable under clause (a) of the previous sentence at
any time shall be calculated on the basis of the total of the Shares subject to
both Options and the Options shall become exercisable as to that number of
Shares first under the Incentive Stock Option and then under the Nonqualified
Option, unless the rule set forth in Section 5.4(c) below would defer the
exercisability of such Incentive Stock Option, in which case such Nonqualified
Options shall become exercisable first. Notwithstanding the terms of any Option,
the preceding sentence and Section 5.4, all Options that have not previously
been exercised nor lapsed and ceased to be exercisable shall vest and become
exercisable upon the occurrence of any Change in Control if the Grantee is an
Employee or Consultant at time of the Change in Control.

      Section 5.4. Incentive Stock Options.

            (a) The Committee shall determine whether any Option is an Incentive
Stock Option or a Nonqualified Option at the time that it is granted, and if no
express determination is made by the Committee, all Options granted to
Participants who are Employees and who are not Ten Percent Stockholders are
Incentive Stock Options and all Options granted to Ten Percent Stockholders or
Consultants are Nonqualified Options.

            (b) If the Committee grants Incentive Stock Options, they shall be
on such terms and conditions as may be necessary to render them "incentive stock
options" pursuant to Section 422 of the Code.

            (c) The aggregate Fair Market Value of the Shares, determined as of
the time the Option is granted, which first become exercisable under all
Incentive Stock Options granted under this Plan or any other plan of the Company
or any Parent or Subsidiary of the Company, shall not exceed one hundred
thousand dollars ($100,000) during any calendar year and if the foregoing limit
would be exceeded in any given calendar year by the terms of any Incentive Stock
Option granted hereunder, the exercisability of such portion of such Option as
would exceed such limit shall be deferred to the first day of the next calendar
year and if such excess involves more than one Option, the exercisability of the
most recently granted Option shall be deferred first.

            (d) If the employment of a Participant, who holds an ISO, with the
Company is terminated because of a "disability" (within the meaning of Section
22(e)(3) of the Code), the unexercised portion of his ISO may only be exercised
within six (6) months after the date on which his employment was terminated, and
only to the extent that such Participant could have otherwise exercised such ISO
as of the date of termination. If a Participant, who holds an ISO, dies while he
is employed by the Company (or within six (6) months after termination of his
employment by reason of a disability or within one (1) month after termination
of his employment without cause), the unexercised portion of his ISO at the time
of his death may only be exercised within six (6) months after the date of his
death, and only to the extent that he could have otherwise exercised such ISO at
the time of his death. In such event, such ISO may be exercised by the executor
or administrator of his estate or by any Holder.

            (e) No Ten Percent Stockholder shall be granted an Incentive Stock
Option, unless at the time such Incentive Stock Option is granted, the Exercise
Price thereof is at least one hundred ten percent (110%) of the Fair Market
Value of a Share on the Date of Grant and the Incentive Stock Option by its
terms is not exercisable after the expiration of five (5) years from the Date of
Grant.

            (f) If a Grantee exercises an Incentive Stock Option and disposes of
any of the Shares received by such Grantee as a result of such exercise within
two (2) years from the Date of Grant or within one (1) year after the transfer
of such Shares to such Grantee upon such exercise, such Grantee shall notify the
Company of such disposition and the consideration


                                      -6-
<PAGE>   7

received as a result thereof and pay or provide for the withholding taxes on
such disposition as required by Section 9.4 below.

            (g) An Option that is designated as a Nonqualified Option under this
Plan shall not be treated as an "incentive stock option" as such term is defined
in Section 422(b) of the Code.

      Section 5.5. Exercise. An Option shall be exercised by the delivery of the
Option Agreement therefor with the notice of exercise attached thereto properly
completed and duly executed by the Holder named therein to the Treasurer of the
Company, together with the aggregate Exercise Price for the number of Shares as
to which the Option is being exercised, after the Option has become exercisable
and before it has ceased to be exercisable. An Option may be exercised as to
less than all of the Shares purchasable thereunder, but not for a fractional
share. No Option may be exercised as to less than one hundred (100) Shares
unless it is exercised as to all of the Shares then available thereunder. If an
Option is exercised as to less than all of the Shares purchasable thereunder, a
new duly executed Option Agreement reflecting the decreased number of Shares
exercisable under such Option, but otherwise of the same tenor, shall be
returned to the Holder. The Committee may, in its sole discretion, and upon such
terms and conditions as it shall determine at or after the Date of Grant, permit
the Exercise Price to be paid in cash, by the tender to the Company of Shares
owned by the Holder or by a combination thereof. If the Committee does not make
such determination, the Exercise Price shall be paid in cash. If any portion of
the Exercise Price of an Option is payable in cash, it may be paid by (a)
delivery of a certified or cashier's check payable to the order of the Company
in such amount, (b) wire transfer of immediately available funds to a bank
account designated by the Company, or (c) reduction of a debt of the Company to
the Holder. If any portion of the Exercise Price of an Option is payable in
Shares it may be paid by delivery of certificates representing a number of
Shares having a total Fair Market Value on the date of delivery equal to or
greater than the required amount, duly endorsed for transfer with all signatures
guaranteed by a bank or a member of the National Association of Securities
Dealers with a medallion guarantee. If more Shares than are necessary to pay
such Exercise Price based on their Fair Market Value on the date of first
delivery to the Company are delivered to the Company, it shall return to the
Holder a certificate for the balance of the whole number of Shares and a check
payable to the order of the Holder for any fraction of a Share. Shares may not
be delivered to the Company as payment for the exercise of an Option, if such
Shares have been owned by the Holder (together with his decedent or testator)
for less than six (6) months or if the disposition of such Shares would require
the giving of a notice under Section 5.4(f) above. Promptly after an Option is
properly exercised, the Company shall issue to the Grantee a certificate
representing the Shares purchased thereunder.

      Section 5.6. Option Agreement. Promptly after the Date of Grant, Neoprobe
shall duly execute and deliver to the Grantee an Option Agreement setting forth
the terms of the Option. Option Agreements are not negotiable instruments or
securities (as such term is defined in Article 8 of the Uniform Commercial
Code). Lost and destroyed Option Agreements may be replaced without bond.

      Section 5.7. New Hires. A person to whom the Company is offering
employment may be granted a Nonqualified Option under this Article 5, but any
such grant shall lapse if the person does not subsequently become an Employee
pursuant to such offer.

      Section 5.8. Acceleration. Notwithstanding anything else in the Plan, the
Committee may, in its sole discretion, at any time or from time to time
thereafter, accelerate the time at which any Options become exercisable or waive
any provisions of the Plan relating to the manner of payment or procedures for
the exercise of any Option. Any such acceleration may be made effective (a) with
respect to one or more or all Grantees, (b) with respect to some or all of the
Shares subject to an Option of any Grantee or (c) for a period of time ending at
or before the expiration date of any Option.

Article 6. Directors' Stock Options.

      Section 6.1. Grant. On each Meeting Date (beginning with the Meeting Date
in 1997), an Option to purchase five thousand (5,000) Shares or such lesser
number as remain available for granting under Article 3 above shall be
automatically granted to each


                                      -7-
<PAGE>   8

Director who is eligible to receive Options under Section 4.2 above and who
attended at least seventy five per cent (75%) of the total number of meetings of
the Board of Directors (and committees thereof of which he is a member) during
the most recently ended fiscal year of the Company. The Board of Directors may,
by a resolution adopted on or before a Meeting Date uniformly applying to all
eligible Directors, increase or decrease the number of Shares subject to the
Option granted under this Section 6.1 on the Meeting Date on which such
resolution is adopted and thereafter.

      Section 6.2.  Exercise  Price.  The Exercise Price of an Option shall be
equal to the Fair Market Value of a Share on the Date of Grant.

      Section 6.3. Term. (a) Each Option shall vest and first become exercisable
as to thirty-three and one-third percent (33-1/3%) of the Shares originally
subject to the Option on each Meeting Date which is held more than six (6)
months after the Date of Grant if the Grantee is a Director at the time of the
adjournment of the meeting of the Board of Directors held on such Meeting Date;
and (b) each Option shall lapse and cease to be exercisable upon the earliest of
(i) the expiration of ten (10) years from the Date of Grant, (ii) nine (9)
months after the Grantee ceases to be a Director because of his death or
disability, (iii) immediately upon resignation by the Grantee as a Director, or
(iv) thirty (30) days after the Grantee ceases to be a Director for any reason
other than his death, disability or resignation. Notwithstanding the foregoing,
all Options that have not previously been exercised nor lapsed and ceased to be
exercisable shall vest and become exercisable upon the occurrence of any Change
in Control if the Grantee is a Director at time of the Change in Control.

      Section 6.4. Not Incentive  Stock Options.  An Option under this Article
6 shall not be treated as an Incentive Stock Option.

      Section 6.5. Exercise. An Option shall be exercised by the delivery of the
Option Agreement therefor with the notice of exercise attached thereto properly
completed and duly executed by the Grantee named therein to the Treasurer of the
Company, together with the aggregate Exercise Price for the number of Shares as
to which the Option is being exercised, after the Option has become exercisable
and before it has ceased to be exercisable. An Option may be exercised as to
less than all of the Shares purchasable thereunder but not for a fractional
Share. No Option may be exercised as to less than one hundred (100) Shares
unless it is exercised as to all of the Shares then available thereunder. If an
Option is exercised as to less than all of the Shares purchasable thereunder, a
new duly executed Option Agreement reflecting the decreased number of Shares
exercisable under such Option, but otherwise of the same tenor, shall be
returned to the Grantee. The Exercise Price shall be paid in cash by (a)
delivery of a certified or cashier's check payable to the order of the Company
in such amount, (b) wire transfer of immediately available funds to a bank
account designated by the Company, or (c) reduction of a debt of the Company to
the Grantee. Promptly after an Option is properly exercised, the Company shall
issue to the Grantee a certificate representing the Shares purchased thereunder.

      Section 6.6. Option Agreement. Promptly after the Date of Grant, Neoprobe
shall duly execute and deliver to the Grantee an Option Agreement setting forth
the terms of the Option. Option Agreements are neither negotiable instruments
nor securities (as such term is defined in Article 8 of the Uniform Commercial
Code). Lost and destroyed Option Agreements may be replaced without bond.

Article 7. Restricted Stock.

      Section 7.1. Determinations. The Committee shall determine which
Participants may purchase Restricted Stock, the number of shares of Restricted
Stock each Grantee may purchase, the times when they may purchase Restricted
Stock, the vesting and forfeiture provisions of the Restricted Stock and the
purchase price of the Restricted Stock; provided, however, that the maximum
number of shares of Restricted Stock which may be sold during any fiscal year of
the Company to any Employee shall be one hundred thousand (100,000), and that
the vesting parameters so prescribed shall include (a) the attainment of a
preestablished performance goal that satisfies the requirements of Section
162(m) of the Code and the regulations thereunder and (b) the Committee's
certification in writing of such attainment, whether incorporated in the minutes
of the Committee


                                      -8-
<PAGE>   9

or otherwise. Notwithstanding the terms of any Award granted under this
Section 7, all shares of Restricted Stock that have not previously been
forfeited shall vest fully and become transferable upon the occurrence of any
Change in Control.

      Section 7.2. Agreements. Once the Committee has made the determinations
required by Section 7.1 above with respect to any Grantee, the appropriate
officers of the Company shall enter into a Restricted Stock Purchase Agreement
with the Grantee setting forth the terms determined by the Committee. No Holder
shall have any right to purchase Restricted Stock, hold Restricted Stock, or
exercise any rights as a stockholder of the Company unless and until such Holder
has executed and delivered an appropriately completed form of Restricted Stock
Purchase Agreement to the Company and the Company has delivered a counterpart
thereof, executed by an appropriate officer of the Company, to the Holder.
Restricted Stock Purchase Agreements are neither negotiable instruments nor
securities (as such term is defined in Article 8 of the Uniform Commercial
Code). Lost and destroyed Restricted Stock Purchase Agreements may be replaced
without bond.

Article 8. Unrestricted Stock.

      The Committee may grant Awards of Unrestricted Stock in consideration for
services rendered by a Participant if such services are deemed by the Committee
to have a value to the Company in excess of the par value of the Shares so
awarded; provided, however, that the maximum number of shares of Unrestricted
Stock which may be granted during any fiscal year of the Company to any
Participant shall be twenty five thousand (25,000). The Committee shall
determine which Participants will receive Unrestricted Stock, the number of
shares of Unrestricted Stock each Grantee will receive, the times when each
Grantee shall receive Unrestricted Stock, and the terms and conditions of
individual Unrestricted Stock Awards (which need not be identical). Promptly
after the grant of an Award of Unrestricted Stock, the Company shall issue to
the Grantee a certificate representing the Shares received thereunder. A person
to whom the Company is offering employment may be granted Unrestricted Stock
under this Article 8, but any such grant shall lapse if the person does not
subsequently become an Employee pursuant to such offer.

Article 9. Provisions Applicable to all Types of Awards.

      Section 9.1. Surrender and Exchange. The Committee may permit the
voluntary surrender of all or a portion of any Award to be conditioned upon the
granting to the Participant of a new Award for the same or a different number of
Shares as the Award surrendered, or may require such voluntary surrender as a
condition precedent to a grant of a new Award to such Participant. Subject to
the provisions of the Plan, such new Award shall be exercisable at the price,
during the period and on such other terms and conditions as are specified by the
Committee at the time the new Award is granted. Upon surrender, the Award
surrendered shall be canceled and the Shares previously subject to it shall be
available for the grant of other Awards.

      Section 9.2. Corporate Mergers and Acquisitions. The Committee may grant
Awards having terms and conditions which vary from those specified in the Plan
if such Awards are granted in substitution for, or in connection with the
assumption of, existing awards granted by another business entity and assumed or
otherwise agreed to be provided for by Neoprobe pursuant to or by reason of a
transaction involving a merger or consolidation of or acquisition of
substantially all of the assets or stock of another business entity that is not
a Subsidiary of Neoprobe prior to such acquisition, with or by Neoprobe or its
Subsidiaries.

      Section 9.3. Actions by Committee After Grant. The Committee shall,
subject to the written consent of the Grantee where the action impairs or
adversely alters the rights of the Grantee, have the right at any time and from
time to time after the Date of Grant of any Award to modify the terms of any
Award.

      Section 9.4. Withholding. The Company shall have the right to withhold
from any payments due under any Award or due to any Grantee from the Company as
compensation or otherwise the amounts of any federal, state or local withholding
taxes not paid by the Grantee at the time of the exercise or vesting of any
Award or upon a disposition of Shares


                                      -9-
<PAGE>   10

received upon the exercise of an Incentive Stock Option. If cash payments
sufficient to allow for withholding of taxes are not made at the time of
exercise or vesting of an Award, the Grantee exercising such Award shall pay to
Neoprobe an amount equal to the withholding required to be made less the
withholding otherwise made in cash or, if allowed by the Committee in its
discretion and pursuant to rules adopted by the Committee consistent with
Section 5.5 above, Shares previously owned by the Grantee. The Company may make
such other provisions as it deems appropriate to withhold any taxes the Company
determines are required to be withheld in connection with the exercise of any
Award or upon a disqualifying disposition of Shares received upon the exercise
of an Incentive Stock Option, including, but not limited to, the withholding of
Shares from an Award upon such terms and conditions as the Committee may
provide. The Company may require the Participant to satisfy any relevant
withholding requirements before issuing Shares or delivering any Award to the
Participant.

      Section 9.5. Disability. If a Grantee who is an Employee with or
Consultant to the Company is absent from work with the Company because of a
physical or mental disability, for purposes of the Plan, such Grantee will not
be considered to have ended his employment with the Company while he has that
disability, unless he resigns or the Committee decides otherwise. If a Grantee
who is a Director is absent from meetings of the Board of Directors because of a
physical or mental disability, for purposes of the Plan, such Grantee will not
be considered to have ended his service with the Board of Directors while he has
that disability, unless he resigns or is not re-elected by the stockholders.

Article 9. General Provisions.

      Section 9.1. No Right to Employment. Nothing in the Plan or any Award or
any instrument executed pursuant to the Plan will confer upon any Participant
any right to continue to be employed by or provide services to the Company or
affect the right of the Company to terminate the employment of any Participant
or its other relationship with any Participant. Nothing in the Plan or any Award
or any instrument executed pursuant to Article 6 of the Plan will confer upon
any Participant any right to continue to be a Director of the Company or affect
the right of the stockholders to terminate the directorship of any Participant.

      Section 9.2. Limited Liability. The liability of the Company under this
Plan or in connection with any exercise of any Award is limited to the
obligations expressly set forth in the Plan and in the grant of any Award, and
no term or provision of this Plan nor of any Award shall be construed to impose
any duty, obligation or liability on the Company not expressly set forth in the
Plan or any grant of any Award.

      Section 9.3. Assumption of Awards. Upon the dissolution or liquidation of
the Company, or upon a reorganization, merger or consolidation of the Company
with one or more corporations as a result of which the Company is not the
surviving corporation, or upon a sale of substantially all the assets of the
Company to another corporation, any Awards outstanding theretofore granted or
sold hereunder must be assumed by the surviving or purchasing corporation, with
appropriate adjustments as to the number and kind of shares and price.

      Section 9.4. No Transfer. No Award or other benefit under the Plan may be
sold, pledged or otherwise transferred other than by will or the laws of descent
and distribution; and no Award may be exercised during the life of the
Participant to whom it was granted except by such Participant.

      Section 9.5. Expenses. All costs and expenses incurred in connection with
the administration of the Plan including any excise tax imposed upon the
transfer of Shares pursuant to the exercise of an Award shall be borne by the
Company.

      Section 9.6. Notices. Notices and other communications required or
permitted to be made under the Plan shall be in writing and shall be deemed to
have been duly given if personally delivered or if sent by first class mail
addressed (a) if to a Grantee, at his residence address set forth in the records
of the Company or (b) if to the Company, to its President at its principal
executive office.

      Section 9.7. Third Parties. Nothing herein expressed or implied is
intended or shall be construed


                                      -10-
<PAGE>   11

to give any person other than the Grantees any rights or remedies under this
Plan.

      Section 9.8. Saturdays, Sundays and Holidays. Where this Plan authorizes
or requires a payment or performance on a Saturday, Sunday or public holiday,
such payment or performance shall be deemed to be timely if made on the next
succeeding business day; provided, however, that this Section 9.8 shall not be
construed to extend the ten (10) year period referred to in Section 5.3 or the
five (5) year period referred to in Section 5.4(e) above.

      Section 9.9. Rules of Construction. The captions and section numbers
appearing in this Plan are inserted only as a matter of convenience. They do not
define, limit or describe the scope or intent of the provisions of this Plan. In
this Plan words in the singular number include the plural, and in the plural
include the singular; and words of the masculine gender include the feminine and
the neuter, and when the sense so indicates words of the neuter gender may refer
to any gender.

      Section 9.10. Governing Law. The validity, terms, performance and
enforcement of this Plan shall be governed by laws of the State of Delaware that
are applicable to agreements negotiated, executed, delivered and performed
solely in the State of Delaware.

      Section 9.11. Effective Date of the Plan. The Plan shall become effective
upon its approval by the affirmative vote of the holders of a majority of the
outstanding Shares present, or represented, and entitled to vote at a meeting of
the stockholders of Neoprobe. Awards may be granted by the Committee before such
approval, but all Awards so granted shall be conditioned on such approval and
shall be void if such approval is not given within twelve (12) months after the
Effective Date. All Options granted under paragraph (a) of Section 6.1 above
shall be conditioned on such approval and shall be void if such approval is not
given within twelve (12) months after the Effective Date.

      Section 9.12. Amendment and Termination. No Award shall be granted under
the Plan more than ten (10) years after the Effective Date. The Board of
Directors may at any time terminate the Plan, or make such amendment of the Plan
as it may deem advisable; provided, however, that no amendment shall be
effective without the approval of the stockholders of the Company by the
affirmative vote of the holders of a majority of the outstanding Shares present,
or represented, and entitled to vote at a meeting of stockholders duly held, if
it would

            (a) materially increase the benefits accruing to Participants under
the Plan;

            (b) materially increase the number of Shares which may be issued
under the Plan; or

            (c) materially modify the requirements as to eligibility for
participation in the Plan;

and, further, provided, however, that no amendment or termination of the Plan
shall be effective to alter or impair the rights of a Grantee under any Award
made before the adoption of such amendment or termination by the Board of
Directors, without the written consent of such Grantee. No termination or
amendment of this Plan or any Award nor waiver of any right or requirement under
this Plan or any Award shall be binding on the Company unless it is in a writing
duly entered into its records and executed by a duly authorized Officer.


                                      -11-
<PAGE>   12

                                                                       Exhibit A
                              NEOPROBE CORPORATION
                                    Suite 400
                              425 Metro Place North
                             Dublin, Ohio 43017-1367

                                <<Date of Grant>>

<<Name of Grantee>>
<<Street>>
<<City, State, Zip>>

      Congratulations. You have been granted a Stock Option under Neoprobe's
1996 Stock Incentive Plan (the "Plan") on the following terms:

      1. Number of Shares. The number of Shares of Common Stock of Neoprobe
      Corporation that you may purchase under this Option is:<<Number>>

      2. Exercise Price. The exercise price to purchase Shares under this Option
      is: $<<Price>> per Share.

      3. Vesting. One third (1/3) of the Shares originally subject to this
      Option will vest and become exercisable on each anniversary of the <<Date
      of Grant>> if you have been an [Employee][Consultant] of the Company
      continuously from the date of this Agreement shown above through the date
      when such portion of the Option vests[ subject to the special rule
      referred to in paragraph 5 below].

      4. Lapse. This Option will lapse and cease to be exercisable upon the
      earliest of:

            (i)   the expiration of 10 years from the date of this Agreement
                  shown above,

            (ii)  [9][6] months after you cease to be an [Employee][Consultant]
                  because of your death or disability,

            (iii) 90 days after your [employment with][services to] Neoprobe or
                  any Subsidiary [is][are] terminated by Neoprobe or such
                  Subsidiary without cause, or

            (iv)  immediately upon termination of your [employment
                  with][services to] Neoprobe or any Subsidiary by Neoprobe or
                  any Subsidiary for cause or by your resignation.

      5. Taxation. This Option is [an Incentive Stock Option][a Nonqualified
      Option].[ Because this Option is an Incentive Stock Option vesting of a
      portion of this Option or of other Incentive Stock Options held by you may
      be deferred under a special rule set forth in Section 5.4 (c) of the Plan.
      If you exercise this Option and dispose of any of the Shares received by
      you as a result of such exercise within two years from the date above or
      within one year after the transfer of such Shares to you upon such
      exercise, you must notify Neoprobe of such disposition and the amount
      received as a result thereof and pay or provide for the withholding taxes
      on such disposition.] [You will have taxable income upon the exercise of
      this Option. At that time, you must pay to Neoprobe an amount equal to the
      required federal, state, and local tax withholding less any withholding
      otherwise made from your salary or bonus. You must satisfy any relevant
      withholding requirements before Neoprobe issues Shares to you.]

      6. Exercise. This Option may be exercised by the delivery of this
      Agreement with the notice of exercise attached hereto properly completed
      and signed by you to the Treasurer of the Company, together with the
      aggregate Exercise Price for the number of Shares as to which the Option
      is being exercised, after the Option has become exercisable and before it
      has ceased to be exercisable. The Exercise Price must be paid in cash by


                                      -1-
<PAGE>   13

      (a) delivery of a certified or cashier's check payable to the order of
      Neoprobe in such amount, (b) wire transfer of immediately available funds
      to a bank account designated by Neoprobe, or (c) reduction of a debt of
      Neoprobe to you. This Option may be exercised as to less than all of the
      Shares purchasable hereunder, but not for a fractional share, nor may it
      be exercised as to less than one hundred (100) Shares unless it is
      exercised as to all of the Shares then available hereunder. If this Option
      is exercised as to less than all of the Shares purchasable hereunder, a
      new duly executed Option Agreement reflecting the decreased number of
      Shares exercisable under such Option, but otherwise of the same tenor,
      will be returned to you.

      7. No Transfer. This Option may not be sold, pledged nor otherwise
      transferred other than by will or the laws of descent and distribution;
      and it may only be exercised during your lifetime by you. This Agreement
      is neither a negotiable instrument nor a security (as such term is defined
      in Article 8 of the Uniform Commercial Code).

      8. Not An Employment Agreement. This Agreement is not an employment
      agreement and nothing contained herein gives you any right to continue to
      be employed by or provide services to Neoprobe or affects the right of
      Neoprobe to terminate your employment or other relationship with you.

      9. Plan Controls. This Agreement is an Option Agreement (as such term is
      defined in the Plan) under Article 5 of the Plan. The terms of this
      Agreement are subject to, and controlled by, the terms of the Plan, as it
      is now in effect or may be amended from time to time hereafter, which are
      incorporated herein as if they were set forth in full. Any words or
      phrases defined in the Plan have the same meanings in this Agreement.
      Neoprobe will provide you with a copy of the Plan promptly upon your
      written or oral request made to its Vice President--Finance and
      Administration.

      10. Miscellaneous. This Agreement sets forth the entire agreement of the
      parties with respect to the subject matter hereof and it supersedes and
      discharges all prior agreements (written or oral) and negotiations and all
      contemporaneous oral agreements concerning such subject matter. This
      Agreement may not be amended or terminated except by a writing signed by
      the party against whom any such amendment or termination is sought. If any
      one or more provisions of this Agreement shall be found to be illegal or
      unenforceable in any respect, the validity and enforceability of the
      remaining provisions hereof shall not in any way be affected or impaired
      thereby. This Agreement shall be governed by the laws of the State of
      Delaware.

      Please acknowledge your acceptance of this Agreement by signing the
enclosed copy in the space provided below and returning it promptly to Neoprobe.

                                        NEOPROBE CORPORATION


                                        By:
                                           -----------------------------------
                                             <<Name of Officer>>, <<Title>>

Accepted and Agreed to as of 
the date first set forth above:


- --------------------------------------
        <<Name of Grantee>>


                                      -2-
<PAGE>   14

                              OPTION EXERCISE FORM

      The undersigned hereby exercises the right to purchase
_____________________________________ shares of Common Stock of Neoprobe
Corporation pursuant to the Option Agreement dated <<Date of Grant>> under the
Neoprobe Corporation 1996 Stock Incentive Plan.


Date:
     ----------------------------------

                                            ------------------------------------
                                                    <<Name of Grantee>>


- ---------------------------------------


Sign and complete this Option Exercise Form and deliver it to:

                              Neoprobe Corporation
                                Att'n: Treasurer
                              425 Metro Place North
                                    Suite 400
                             Dublin, Ohio 43017-1367

together with the option price in cash by (a) delivery of a certified or
cashier's check payable to the order of Neoprobe in such amount, (b) wire
transfer of immediately available funds to a bank account designated by
Neoprobe, or (c) reduction of a debt of Neoprobe to you.


                                      -3-
<PAGE>   15

                                                                       Exhibit B
                              NEOPROBE CORPORATION
                                    Suite 400
                              425 Metro Place North
                             Dublin, Ohio 43017-1367

                                <<Date of Grant>>

<<Name of Grantee>>
<<Street>>
<<City, State, Zip>>

      Congratulations. You have been granted a Stock Option under Neoprobe's
Stock Option and Restricted Stock Purchase Plan (the "Plan") on the following
terms:

      1. Number of Shares. The number of Shares of Common Stock of Neoprobe
      Corporation that you may purchase under this Option is five thousand
      (5,000).

      2. Exercise Price. The exercise price to purchase Shares under this Option
      is: $<<Price>> per Share.

      3. Vesting. Thirty-three and one-third percent (33-1/3%) of the Shares
      originally subject to this Option will vest and become exercisable on each
      Meeting Date which is held more than six months after the date of this
      Agreement shown above if you are a Director at the time of the adjournment
      of the meeting of stockholders held on such Meeting Date.

      4. Lapse. This Option will lapse and cease to be exercisable upon the
      earliest of:

            (i)   the expiration of 10 years from the date of this Agreement
                  shown above,

            (ii)  9 months after you cease to be a Director because of your
                  death or disability,

            (iii) immediately upon your resignation as a Director, or

            (iv)  30 days after you cease to be a Director for any reason other
                  than your death, disability or resignation.

      5. Taxation. This Option is a Nonqualified Option. You will have taxable
      income upon the exercise of this Option.

      6. Exercise. This Option may be exercised by the delivery of this
      Agreement with the notice of exercise attached hereto properly completed
      and signed by you to the Treasurer of the Company, together with the
      aggregate Exercise Price for the number of Shares as to which the Option
      is being exercised, after the Option has become exercisable and before it
      has ceased to be exercisable. The Exercise Price must be paid in cash by
      (a) delivery of a certified or cashier's check payable to the order of
      Neoprobe in such amount, (b) wire transfer of immediately available funds
      to a bank account designated by Neoprobe, or (c) reduction of a debt of
      Neoprobe to you. This Option may be exercised as to less than all of the
      Shares purchasable hereunder, but not for a fractional share, nor may it
      be exercised as to less than one hundred (100) Shares unless it is
      exercised as to all of the Shares then available hereunder. If this Option
      is exercised as to less than all of the Shares purchasable hereunder, a
      new duly executed Option Agreement reflecting the decreased number of
      Shares exercisable under such Option, but otherwise of the same tenor,
      will be returned to you.

      7. No Transfer. This Option may not be sold, pledged nor otherwise
      transferred other than by will or the laws of descent and distribution;
      and it may only be exercised during your lifetime by you. This Agreement
      is


                                      -4-
<PAGE>   16

      neither a negotiable instrument nor a security (as such term is defined in
      Article 8 of the Uniform Commercial Code).

      8. Not An Employment Agreement. This Agreement is not an employment
      agreement and nothing contained herein gives you any right to continue to
      be a Director of the Company or affect the right of the stockholders to
      terminate your directorship.

      9. Plan Controls. This Agreement is an Option Agreement (as such term is
      defined in the Plan) under Article 6 of the Plan. The terms of this
      Agreement are subject to, and controlled by, the terms of the Plan, as it
      is now in effect or may be amended from time to time hereafter, which are
      incorporated herein as if they were set forth in full. Any words or
      phrases defined in the Plan have the same meanings in this Agreement.
      Neoprobe will provide you with a copy of the Plan promptly upon your
      written or oral request made to its Vice President--Finance and
      Administration.

      10. Miscellaneous. This Agreement sets forth the entire agreement of the
      parties with respect to the subject matter hereof and it supersedes and
      discharges all prior agreements (written or oral) and negotiations and all
      contemporaneous oral agreements concerning such subject matter. This
      Agreement may not be amended or terminated except by a writing signed by
      the party against whom any such amendment or termination is sought. If any
      one or more provisions of this Agreement shall be found to be illegal or
      unenforceable in any respect, the validity and enforceability of the
      remaining provisions hereof shall not in any way be affected or impaired
      thereby. This Agreement shall be governed by the laws of the State of
      Delaware.

      Please acknowledge your acceptance of this Agreement by signing the
enclosed copy in the space provided below and returning it promptly to Neoprobe.

                                        NEOPROBE CORPORATION


                                        By:
                                           -------------------------------------
                                               <<Name of Officer>>, <<Title>>

Accepted and Agreed to as of 
the date first set forth above:


- -----------------------------------
       <<Name of Grantee>>


                                      -5-
<PAGE>   17

                              OPTION EXERCISE FORM

      The undersigned hereby exercises the right to purchase
_____________________________________ shares of Common Stock of Neoprobe
Corporation pursuant to the Option Agreement dated <<Date of Grant>> under the
Neoprobe Corporation Stock Option and Restricted Stock Purchase Plan.


Date:
     ----------------------------------

                                            ------------------------------------
                                                    <<Name of Grantee>>


- ---------------------------------------


Sign and complete this Option Exercise Form and deliver it to:

                              Neoprobe Corporation
                                Att'n: Treasurer
                              425 Metro Place North
                                    Suite 400
                             Dublin, Ohio 43017-1367

together with the option price in cash by (a) delivery of a certified or
cashier's check payable to the order of Neoprobe in such amount, (b) wire
transfer of immediately available funds to a bank account designated by
Neoprobe, or (c) reduction of a debt of Neoprobe to you.


                                      -6-
<PAGE>   18

                                                                       Exhibit C
                                             Restricted Stock Purchase Agreement

                              Neoprobe Corporation
                                    Suite 400
                              425 Metro Place North
                             Dublin, Ohio 43017-1367

                                <<Date of Grant>>

<<Name of Grantee>>
<<Street>>
<<City, State, Zip>>

      Congratulations. You (the "Executive") have been granted a right to
purchase Restricted Stock under the Company's 1996 Stock Incentive Plan (the
"Plan") on the following terms:

      1. Purchase and Sale.

            (a) On the terms and subject to the conditions set forth in this
Agreement, the Executive hereby subscribes for and agrees to purchase __________
shares of Common Stock (the "Restricted Stock") for and in consideration of a
payment to the Company by the Executive of ________________ per share.
Concurrently with the execution of this Agreement, the Executive has delivered
to the Company his check drawn on sufficient funds and payable to the order of
the Company in the amount of $__________ , receipt of which is acknowledged by
the Company. The Executive agrees to deliver to the Secretary of the Company the
certificates representing the Restricted Stock together with stock powers duly
endorsed in blank promptly upon receipt thereof from the transfer agent of the
Company.

            (b) The fair market value of Common Stock is demonstrated by the
closing price on the _____________________ of such securities on the business
day before the date first set forth above which was $________. The Executive and
the Company intend that the transactions provided for in this Agreement will be
governed by the provisions of Section 83(a) of the Internal Revenue Code of
1986.

      2. Transfer Restrictions.

            (a) In consideration of the difference between the purchase price of
the Restricted Stock set forth in Section 1 above and its fair market value
without the restrictions and risk of forfeiture set forth herein, the Executive
agrees that, unless and until any of the Restricted Stock vests and becomes
transferable as provided in Section 4 below, the Executive may neither transfer,
sell, assign nor pledge any of the Restricted Stock.

            (b) This paragraph may be deleted if Shares issuable under the Plan
are registered. The Executive understands the Restricted Stock has neither been
registered under the Securities Act of 1933 nor under any applicable state
securities law on the ground that the sale provided for in this Agreement and
the issuance of securities hereunder are exempt from registration under the
Securities Act of 1933 pursuant to Section 4(2) thereof, but the Company's
reliance on such exemption is predicated on the Executive's representations set
forth herein and that in order to obtain such exemption, the transfer of such
securities is restricted by this paragraph and the legend set forth below. The
Executive represents and warrants to the Company that he or she is purchasing
the Restricted Stock for his or her own account and not for other persons and
for investment and not with a view to the distribution of any of the Restricted
Stock. The Executive will not offer for sale, sell or otherwise transfer any
Restricted Stock, even after it


                                      -7-
<PAGE>   19

has vested and has become transferable under Section 4 below, unless such
securities have been registered under the Securities Act of 1933 and under
applicable state securities laws or such securities or their offer, sale or
transfer are exempt from such registration and the Company has received an
opinion of counsel, in form and substance reasonably satisfactory to the
Company, to that effect.

            (c) Any certificate representing any Restricted Stock issued
hereunder shall bear the following legend:

             THE TRANSFER OF THESE SECURITIES IS RESTRICTED BY, AND SUCH
            SECURITIES ARE SUBJECT TO A RISK OF FORFEITURE, UNDER A RESTRICTED
            STOCK PURCHASE AGREEMENT BETWEEN THE REGISTERED OWNER HEREOF AND THE
            ISSUER DATED __________, 199_. The remainder of this paragraph may
            be deleted if Shares issuable under the Plan are registered. THESE
            SECURITIES HAVE NEITHER BEEN REGISTERED UNDER THE SECURITIES ACT OF
            1933 NOR UNDER ANY APPLICABLE STATE SECURITIES LAW. THESE SECURITIES
            MAY NOT BE OFFERED FOR SALE, SOLD OR OTHERWISE TRANSFERRED UNLESS
            THEY ARE REGISTERED UNDER THE SECURITIES ACT OF 1933 AND UNDER
            APPLICABLE STATE SECURITIES LAWS OR THEY OR SUCH OFFER, SALE OR
            TRANSFER ARE EXEMPT FROM SUCH REGISTRATION AND THE COMPANY HAS
            RECEIVED AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE
            COMPANY IN FORM AND SUBSTANCE, TO THAT EFFECT.

      3. Forfeiture. The Executive will forfeit any portion of the Restricted
Stock purchased under this Agreement that has not vested and become transferable
on the earliest of:

            (a)   the expiration of 10 years from the date of this Agreement,

            (b)   nine months after Executive ceases to be an Employee because
                  of Executive's death or disability,

            (c)   90 days after the termination without cause of Executive's
                  employment with the Employer, or

            (d)   immediately upon termination of Executive's employment with
                  the Employer by the Employer for cause or by Executive's
                  resignation.

Upon the occurrence of such forfeiture all of the right, title and interest in
and to any shares of Restricted Stock which has been forfeited shall be
terminated and the Company shall cause the certificates representing the
forfeited shares to be canceled or transferred free and clear of all
restrictions to its treasury and the Company shall pay to the Executive
____________ per share for each share so forfeited.

      4. Vesting Provisions.

            (a) A portion of the Restricted Stock that has not previously been
forfeited under Section 3 above shall vest and become transferable if and when
the Company attains (and the Committee certifies in its minutes or another
writing the attainment of) a preestablished performance goal that satisfies the
requirements of Section 162(m) of the Code and the regulations thereunder as
follows: [* Insert vesting formula based on one or more business criteria that
apply to the individual Executive, a business unit or the Company as a whole.
Such business criteria may include one or a combination of stock price, total
stockholder return, earnings per share or return on equity. Other business
criteria may be statistics relating to economic performance including revenue,
operating expenses, or earnings before interest, taxes, depreciation and
amortization; or the business criteria may be the achievement of a
non-statistical goal such as the introduction, testing or licensing of a new
product, licensing or acquiring assets or rights, entering into a joint venture
or strategic alliance, or a change in control of the Company or another merger
or acquisition. *].


                                      -8-
<PAGE>   20

            (b) When any portion of the Restricted Stock vests and becomes
transferable, the Company shall promptly deliver a certificate (free of all
adverse claims and transfer restrictions other than the restriction imposed by
paragraph (b) of Section 2 above) representing the number of shares constituting
the vested and transferable portion of the Restricted Stock to the Executive at
his or her address given above and such shares shall no longer be deemed to be
Restricted Stock subject to the terms and conditions of this Agreement other
than paragraph (b) of Section 2 above.

      5. Rights; Stock Dividends. Except for the restrictions on transfer set
forth in Section 2 and the possibility of forfeiture set forth in Section 3,
upon the issuance of a certificate representing shares of Restricted Stock, the
Executive will have all other rights in such shares, including the right to vote
such shares and receive dividends other than dividends on or distributions of
shares of any class of stock issued by the Company which dividends or
distributions shall be delivered to the Company under the same restrictions on
transfer and possibility of forfeitures as the shares of Restricted Stock from
which they derive. Upon the occurrence of such a dividend or distribution the
dollar amounts set forth in Paragraph (a) of Section 4 shall be appropriately
adjusted by the Committee.

      6. Taxation. Both you and we intend that the transactions provided for in
this Agreement will be governed by the provisions of Section 83(a) of the
Internal Revenue Code of 1986. You will have taxable income upon the vesting of
Restricted Stock. At that time, you must pay to the Company an amount equal to
the required federal, state, and local tax withholding less any withholding
otherwise made from your salary or bonus. You must satisfy any relevant
withholding requirements before the Company issues Shares to you.

      7. Not An Employment Agreement. This Agreement is not an employment
agreement and nothing contained herein gives you any right to continue to be
employed by or provide services to the Company or affects the right of the
Company to terminate your employment or other relationship with you.

      8. Plan Controls. This Agreement is a Restricted Stock Purchase Agreement
(as such term is defined in the Plan) under Article 7 of the Plan. The terms of
this Agreement are subject to, and controlled by, the terms of the Plan, as it
is now in effect or may be amended from time to time hereafter, which are
incorporated herein as if they were set forth in full. Any words or phrases
defined in the Plan have the same meanings in this Agreement. The Company will
provide you with a copy of the Plan promptly upon your written or oral request
made to its Treasurer.

      9. Miscellaneous. This Agreement sets forth the entire agreement of the
parties with respect to the subject matter hereof and it supersedes and
discharges all prior agreements (written or oral) and negotiations and all
contemporaneous oral agreements concerning such subject matter. This Agreement
may not be amended or terminated except by a writing signed by the party against
whom any such amendment or termination is sought. If any one or more provisions
of this Agreement shall be found to be illegal or unenforceable in any respect,
the validity and enforceability of the remaining provisions hereof shall not in
any way be affected or impaired thereby. This Agreement shall be governed by the
laws of the State of Delaware.


                                      -9-
<PAGE>   21

      Please acknowledge your acceptance of this Agreement by signing the
enclosed copy in the space provided below and returning it promptly to the
Company.

                                        NEOPROBE CORPORATION


                                       By:
                                          --------------------------------------
                                             <<Name of Officer>>, <<Title>>

Accepted and Agreed to as of 
the date first set forth above:


- ------------------------------------
        <<Name of Grantee>>


                                      -10-


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